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Conserved domains on  [gi|1370462245|ref|XP_024304803|]
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coiled-coil domain-containing protein 91 isoform X2 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 94-369 1.46e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  94 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISfQDRYKELQEKHKQELEDMRKAGHEALSI 173
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL-LAELARLEQDIARLEERRRELEERLEEL 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 174 IVDEYKALLQ-SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRL-LEMLDTEKELLKEKIKEALIQQSQEQKEILEK 251
Cdd:COG1196   322 EEELAELEEElEELEEELEELEEELEEAEEELEEAEAELAEAEEALLeAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 252 CLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAhAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETV 331
Cdd:COG1196   402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1370462245 332 KAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQ 369
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 94-369 1.46e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  94 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISfQDRYKELQEKHKQELEDMRKAGHEALSI 173
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL-LAELARLEQDIARLEERRRELEERLEEL 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 174 IVDEYKALLQ-SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRL-LEMLDTEKELLKEKIKEALIQQSQEQKEILEK 251
Cdd:COG1196   322 EEELAELEEElEELEEELEELEEELEEAEEELEEAEAELAEAEEALLeAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 252 CLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAhAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETV 331
Cdd:COG1196   402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1370462245 332 KAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQ 369
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
PTZ00121 PTZ00121
MAEBL; Provisional
 96-389 3.73e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 3.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245   96 QQKISSLEIKLKVSEEEK-QRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAgHEALSII 174
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA-DEAKKKA 1453

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  175 VDEYKAllQSSVKQQVEAIEKQYISAIEKQAHKCEELlNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLE 254
Cdd:PTZ00121  1454 EEAKKA--EEAKKKAEEAKKADEAKKKAEEAKKADEA-KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  255 EERQRNKEALVSAAKLEKEAVKDAV-LKVVEEERKNLEKAHAEERELWKTEHA----KDQEKVSQEIQKAIQEQRKISQE 329
Cdd:PTZ00121  1531 EEAKKADEAKKAEEKKKADELKKAEeLKKAEEKKKAEEAKKAEEDKNMALRKAeeakKAEEARIEEVMKLYEEEKKMKAE 1610

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  330 TVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQ 389
Cdd:PTZ00121  1611 EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 110-402 6.60e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 6.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 110 EEEKQRIKQ-DVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGhealsiIVDEYKALLQSSVKQ 188
Cdd:pfam17380 347 ERELERIRQeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVK------ILEEERQRKIQQQKV 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 189 QVEAIEKQYISAIEKQAHKCEELLNAQHQRLlemldTEKELLKEKIKEALIQQSQEQKeilEKCLEEERQRNKEALVSaa 268
Cdd:pfam17380 421 EMEQIRAEQEEARQREVRRLEEERAREMERV-----RLEEQERQQQVERLRQQEEERK---RKKLELEKEKRDRKRAE-- 490

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 269 klekeavkdavlkvvEEERKNLEKAHAEERELWKTEHAKDQ--EKVSQEIQKAIQEQRkisqetvKAAIIEEQKRSEKAV 346
Cdd:pfam17380 491 ---------------EQRRKILEKELEERKQAMIEEERKRKllEKEMEERQKAIYEEE-------RRREAEEERRKQQEM 548

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370462245 347 EEAvKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQLSAliATEPVDIE 402
Cdd:pfam17380 549 EER-RRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEA--TTPITTIK 601
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 126-373 7.82e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 7.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  126 KHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEalsiivdeyKALLQSSVKQQVEAIEKQYISAIEKQA 205
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE---------LSRQISALRKDLARLEAEVEQLEERIA 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  206 HKCEELLNAQHQRllEMLDTEKELLKEKIKEALIQQSQEQKEILEkcLEEERQRNKEALvSAAKLEKEAVKDAVLKVVEE 285
Cdd:TIGR02168  751 QLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELEAQIEQ--LKEELKALREAL-DELRAELTLLNEEAANLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  286 ERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKaVEEAVKRTRDELIEYIKEQK 365
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS-LEEALALLRSELEELSEELR 904


                   ....*...
gi 1370462245  366 RLDQVIRQ 373
Cdd:TIGR02168  905 ELESKRSE 912
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 94-369 1.46e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  94 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISfQDRYKELQEKHKQELEDMRKAGHEALSI 173
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL-LAELARLEQDIARLEERRRELEERLEEL 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 174 IVDEYKALLQ-SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRL-LEMLDTEKELLKEKIKEALIQQSQEQKEILEK 251
Cdd:COG1196   322 EEELAELEEElEELEEELEELEEELEEAEEELEEAEAELAEAEEALLeAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 252 CLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAhAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETV 331
Cdd:COG1196   402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1370462245 332 KAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQ 369
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 93-349 1.68e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 1.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  93 IQLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGfLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALS 172
Cdd:COG1196   298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 173 IIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAhkceellnAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEkc 252
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEAE--------EALLERLERLEEELEELEEALAELEEEEEEEEEALEE-- 446

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 253 LEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVK 332
Cdd:COG1196   447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                         250
                  ....*....|....*..
gi 1370462245 333 AAIIEEQKRSEKAVEEA 349
Cdd:COG1196   527 AVLIGVEAAYEAALEAA 543
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 135-400 1.53e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 135 LKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNA 214
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 215 QHQRLLEMLDTEKELLKEkikealIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDavlkvvEEERKNLEKAH 294
Cdd:COG1196   314 LEERLEELEEELAELEEE------LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA------EAELAEAEEEL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 295 AEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQR 374
Cdd:COG1196   382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         250       260
                  ....*....|....*....|....*.
gi 1370462245 375 SLSSLELFLSCAQKQLSALIATEPVD 400
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELA 487
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 105-373 1.76e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 105 KLKVSEEEKQRIKQDVESLMEKHNVLEKGfLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSIIVD-EYKALLQ 183
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAE-LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiARLEERR 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 184 SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQrlLEMLDTEKELLKEKIKEALIQQSQEQKEILEKclEEERQRNKEA 263
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEE--LEEAEEELEEAEAELAEAEEALLEAEAELAEA--EEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 264 LVSAAKLEKEAVKD-AVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRS 342
Cdd:COG1196   388 LLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1370462245 343 EKAVEEAVKRTRDELIEYIKEQKRLDQVIRQ 373
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLE 498
PTZ00121 PTZ00121
MAEBL; Provisional
 96-389 3.73e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 3.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245   96 QQKISSLEIKLKVSEEEK-QRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAgHEALSII 174
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA-DEAKKKA 1453

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  175 VDEYKAllQSSVKQQVEAIEKQYISAIEKQAHKCEELlNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLE 254
Cdd:PTZ00121  1454 EEAKKA--EEAKKKAEEAKKADEAKKKAEEAKKADEA-KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  255 EERQRNKEALVSAAKLEKEAVKDAV-LKVVEEERKNLEKAHAEERELWKTEHA----KDQEKVSQEIQKAIQEQRKISQE 329
Cdd:PTZ00121  1531 EEAKKADEAKKAEEKKKADELKKAEeLKKAEEKKKAEEAKKAEEDKNMALRKAeeakKAEEARIEEVMKLYEEEKKMKAE 1610

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  330 TVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQ 389
Cdd:PTZ00121  1611 EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 110-402 6.60e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 6.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 110 EEEKQRIKQ-DVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGhealsiIVDEYKALLQSSVKQ 188
Cdd:pfam17380 347 ERELERIRQeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVK------ILEEERQRKIQQQKV 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 189 QVEAIEKQYISAIEKQAHKCEELLNAQHQRLlemldTEKELLKEKIKEALIQQSQEQKeilEKCLEEERQRNKEALVSaa 268
Cdd:pfam17380 421 EMEQIRAEQEEARQREVRRLEEERAREMERV-----RLEEQERQQQVERLRQQEEERK---RKKLELEKEKRDRKRAE-- 490

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 269 klekeavkdavlkvvEEERKNLEKAHAEERELWKTEHAKDQ--EKVSQEIQKAIQEQRkisqetvKAAIIEEQKRSEKAV 346
Cdd:pfam17380 491 ---------------EQRRKILEKELEERKQAMIEEERKRKllEKEMEERQKAIYEEE-------RRREAEEERRKQQEM 548

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370462245 347 EEAvKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQLSAliATEPVDIE 402
Cdd:pfam17380 549 EER-RRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEA--TTPITTIK 601
PTZ00121 PTZ00121
MAEBL; Provisional
 107-365 1.72e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  107 KVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQEL---EDMRKAgHEALSIIVDEYKALLQ 183
Cdd:PTZ00121  1504 KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELkkaEEKKKA-EEAKKAEEDKNMALRK 1582

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  184 SSVKQQVEA--IEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNK 261
Cdd:PTZ00121  1583 AEEAKKAEEarIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  262 EALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQE----KVSQEIQKAiQEQRKISQETVKAAIIE 337
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEaeekKKAEELKKA-EEENKIKAEEAKKEAEE 1741

                          250       260
                   ....*....|....*....|....*...
gi 1370462245  338 EQKRSEKAVEEAVKRTRDELIEYIKEQK 365
Cdd:PTZ00121  1742 DKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
PTZ00121 PTZ00121
MAEBL; Provisional
 103-368 1.93e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  103 EIKLKVSEEEKQRIKQDVESLmEKHNVLEKGFLKEKEQEAISFQDRyKELQEKHKQELEDMRKAGHEALSIIVDEYKALL 182
Cdd:PTZ00121  1531 EEAKKADEAKKAEEKKKADEL-KKAEELKKAEEKKKAEEAKKAEED-KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  183 QSSVKQQVEA-IEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQ--KEILEKCLEEERQR 259
Cdd:PTZ00121  1609 AEEAKKAEEAkIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkKKAEEAKKAEEDEK 1688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  260 NKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQE----KVSQEIQKAIQEQRKISQETVKAAI 335
Cdd:PTZ00121  1689 KAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAeedkKKAEEAKKDEEEKKKIAHLKKEEEK 1768

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1370462245  336 IEEQKRSEK--AVEEAVKRtRDELIEYIKEQKRLD 368
Cdd:PTZ00121  1769 KAEEIRKEKeaVIEEELDE-EDEKRRMEVDKKIKD 1802
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 151-373 7.73e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 7.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 151 ELQEKHKQELEDMRKAGHEALSIIVDEYKAllQSSVKQQVEAIEKQyISAIEKQAHKCEELLNAQHQRLlemldTEKELL 230
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKE--EKALLKQLAALERR-IAALARRIRALEQELAALEAEL-----AELEKE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 231 KEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEER-ELWKTEHAKDQ 309
Cdd:COG4942    92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLaELAALRAELEA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370462245 310 EKVSQEIQKAIQEQRKISQETVKAaiieEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQ 373
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 126-373 7.82e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 7.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  126 KHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEalsiivdeyKALLQSSVKQQVEAIEKQYISAIEKQA 205
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE---------LSRQISALRKDLARLEAEVEQLEERIA 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  206 HKCEELLNAQHQRllEMLDTEKELLKEKIKEALIQQSQEQKEILEkcLEEERQRNKEALvSAAKLEKEAVKDAVLKVVEE 285
Cdd:TIGR02168  751 QLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELEAQIEQ--LKEELKALREAL-DELRAELTLLNEEAANLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  286 ERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKaVEEAVKRTRDELIEYIKEQK 365
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS-LEEALALLRSELEELSEELR 904


                   ....*...
gi 1370462245  366 RLDQVIRQ 373
Cdd:TIGR02168  905 ELESKRSE 912
PTZ00121 PTZ00121
MAEBL; Provisional
 105-366 3.69e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 3.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  105 KLKVSEEEKQRIKQDVESLMEKHNVLEKgflkekEQEAISFQDRYKELQEKHKQELEDMRKAghEALSIIVDEYKALLQS 184
Cdd:PTZ00121  1358 EAEAAEEKAEAAEKKKEEAKKKADAAKK------KAEEKKKADEAKKKAEEDKKKADELKKA--AAAKKKADEAKKKAEE 1429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  185 SVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEAL 264
Cdd:PTZ00121  1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK 1509

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  265 VSAAKLEK--EAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRS 342
Cdd:PTZ00121  1510 KKADEAKKaeEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589

                          250       260
                   ....*....|....*....|....
gi 1370462245  343 EKAVEEAVKRTRDELIEYIKEQKR 366
Cdd:PTZ00121  1590 EEARIEEVMKLYEEEKKMKAEEAK 1613
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 94-368 3.74e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 3.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245   94 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGF------LKEKEQEAISFQDRYkELQEKHKQELEDMRKAG 167
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIsalrkdLARLEAEVEQLEERI-AQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  168 HEALSIIVDEYKALLQ--SSVKQQVEAIEKQyISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKI-KEALIQQSQE 244
Cdd:TIGR02168  767 EERLEEAEEELAEAEAeiEELEAQIEQLKEE-LKALREALDELRAELTLLNEEAANLRERLESLERRIAaTERRLEDLEE 845

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  245 QKEILEKCLEEERQRNKEALVSAAKLEKEavkdavLKVVEEERKNLEKAHAEERElwktehakDQEKVSQEIQKAIQEQR 324
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESE------LEALLNERASLEEALALLRS--------ELEELSEELRELESKRS 911

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1370462245  325 KISQETVKAaiiEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLD 368
Cdd:TIGR02168  912 ELRRELEEL---REKLAQLELRLEGLEVRIDNLQERLSEEYSLT 952
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
106-292 5.96e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 5.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  106 LKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMR--KAGHEALSIIVDEYKALLQ 183
Cdd:COG4913    254 LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELErlEARLDALREELDELEAQIR 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  184 SSVKQQVEAIEKQyISAIEKQAHKCEELLNAQHQRL----LEMLDTEKELlkekikEALIQQSQEQKEILEKCLEEERQR 259
Cdd:COG4913    334 GNGGDRLEQLERE-IERLERELEERERRRARLEALLaalgLPLPASAEEF------AALRAEAAALLEALEEELEALEEA 406

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1370462245  260 NKEALVSAAKLEKEavkdavLKVVEEERKNLEK 292
Cdd:COG4913    407 LAEAEAALRDLRRE------LRELEAEIASLER 433
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 94-365 7.09e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 7.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245   94 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGF-------------LKEKEQEAISFQDRYKELQEKHKQEL 160
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIeelqkelyalaneISRLEQQKQILRERLANLERQLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  161 EDMRKAGHEAlsiivDEYKALLQsSVKQQVEAIEKQYISAIEKQAHKCEELLNAqhQRLLEMLDTEKELLKEKIKEALIQ 240
Cdd:TIGR02168  323 AQLEELESKL-----DELAEELA-ELEEKLEELKEELESLEAELEELEAELEEL--ESRLEELEEQLETLRSKVAQLELQ 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  241 QSQEQKEILE-----KCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEhakdqEKVSQE 315
Cdd:TIGR02168  395 IASLNNEIERlearlERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEAL-----EELREE 469

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1370462245  316 IQKAIQEQRKISQEtvkaaiiEEQKRSEKAVEEAVKRTRDELIEYIKEQK 365
Cdd:TIGR02168  470 LEEAEQALDAAERE-------LAQLQARLDSLERLQENLEGFSEGVKALL 512
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 148-374 7.86e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 7.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  148 RYKELQEKhKQELEdmrkagheaLSIIVDEYKALLQssvkqQVEAIEKQyISAIEKQAHKCEELLNAQHQRLLEMLDTEK 227
Cdd:TIGR02169  212 RYQALLKE-KREYE---------GYELLKEKEALER-----QKEAIERQ-LASLEEELEKLTEEISELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  228 ELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEAlvsAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELwkTEHAK 307
Cdd:TIGR02169  276 ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIA---EKERELEDAEERLAKLEAEIDKLLAEIEELEREI--EEERK 350

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370462245  308 DQEKVSQEIQKAIQEQRKISQEtvkaaiIEEqkrsekaVEEAVKRTRDELIEYikeQKRLDQVIRQR 374
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAE------LEE-------VDKEFAETRDELKDY---REKLEKLKREI 401
PTZ00121 PTZ00121
MAEBL; Provisional
 150-373 1.37e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  150 KELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKEL 229
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADE 1319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  230 LKEKIKEALiQQSQEQKEILEKCLEEERQRNKEALVSAAKLEK-EAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAK- 307
Cdd:PTZ00121  1320 AKKKAEEAK-KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAaEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKk 1398

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  308 ---DQEKVSQEIQKAIQEQRKISQETVKAaiiEEQKRSEKAVEEAV-KRTRDELIEYIKEQKRLDQVIRQ 373
Cdd:PTZ00121  1399 kaeEDKKKADELKKAAAAKKKADEAKKKA---EEKKKADEAKKKAEeAKKADEAKKKAEEAKKAEEAKKK 1465
PTZ00121 PTZ00121
MAEBL; Provisional
 126-370 1.52e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  126 KHNVLEKGFLKEKEQEAISFQDRYKelQEKHKQELEDMRKAghEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQA 205
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAKKAEEKKK--ADEAKKKAEEAKKA--DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  206 HKcEELLNAQHQRLLEMLDTEKEllkEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVveE 285
Cdd:PTZ00121  1355 AA-DEAEAAEEKAEAAEKKKEEA---KKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKA--E 1428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  286 ERKNLEKAHAEERELWKTEHAK---DQEKVSQEIQKAIQEQRKISQETVKAaiiEEQKRSEKAVEEA--VKRTRDELIEY 360
Cdd:PTZ00121  1429 EKKKADEAKKKAEEAKKADEAKkkaEEAKKAEEAKKKAEEAKKADEAKKKA---EEAKKADEAKKKAeeAKKKADEAKKA 1505

                          250
                   ....*....|
gi 1370462245  361 IKEQKRLDQV 370
Cdd:PTZ00121  1506 AEAKKKADEA 1515
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 94-302 2.14e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245   94 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKhnvlekgfLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSI 173
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAE--------LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  174 ivdeykALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEaliqqsQEQKEILEKCL 253
Cdd:TIGR02168  399 ------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE------LERLEEALEEL 466

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1370462245  254 EEERQRNKEALVSAAklEKEAVKDAVLKVVEEERKNLEKAHAEERELWK 302
Cdd:TIGR02168  467 REELEEAEQALDAAE--RELAQLQARLDSLERLQENLEGFSEGVKALLK 513
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 94-358 2.40e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.75  E-value: 2.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  94 QLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKgFLKEKEQEAISFQDRYKELQEKHKQeledmrkaghealsi 173
Cdd:COG4942    31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-RIRALEQELAALEAELAELEKEIAE--------------- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 174 ivdeykalLQSSVKQQVEAIEKQYISAIEKQAHKCEELL-----NAQHQRLLEMLDTEKELLKEKIKEalIQQSQEQKEI 248
Cdd:COG4942    95 --------LRAELEAQKEELAELLRALYRLGRQPPLALLlspedFLDAVRRLQYLKYLAPARREQAEE--LRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 249 LEKCLEEERQRnkealvsaaklekeavKDAVLKVVEEERKNLEKAHAEERELwKTEHAKDQEKVSQEIQKAIQEQRKIsQ 328
Cdd:COG4942   165 LRAELEAERAE----------------LEALLAELEEERAALEALKAERQKL-LARLEKELAELAAELAELQQEAEEL-E 226

                         250       260       270
                  ....*....|....*....|....*....|
gi 1370462245 329 ETVKAAIIEEQKRSEKAVEEAVKRTRDELI 358
Cdd:COG4942   227 ALIARLEAEAAAAAERTPAAGFAALKGKLP 256
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 157-279 6.06e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 38.65  E-value: 6.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 157 KQELEDMrKAGHEALSIIVDEYKALLQSsVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKE 236
Cdd:PRK00409  515 KEKLNEL-IASLEELERELEQKAEEAEA-LLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKE 592

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1370462245 237 ALIQQSQEQKEILEKCLEEERQRNKEAL--VSAAKLEKEAVKDAV 279
Cdd:PRK00409  593 LRQLQKGGYASVKAHELIEARKRLNKANekKEKKKKKQKEKQEEL 637
PTZ00121 PTZ00121
MAEBL; Provisional
 161-369 6.89e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 6.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  161 EDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQyisaieKQAHKCEELLNAQHQRLLEMLDTEKELLKekiKEALIQ 240
Cdd:PTZ00121  1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKA------EEERKAEEARKAEDAKKAEAVKKAEEAKK---DAEEAK 1243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  241 QSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERElwKTEHAK---DQEKVSQEIQ 317
Cdd:PTZ00121  1244 KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK--KADEAKkkaEEAKKADEAK 1321

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370462245  318 KAIQEQRKISQETVKAAiiEEQKRSEKAVEEAVKRTRDELiEYIKEQKRLDQ 369
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKA--EEAKKAAEAAKAEAEAAADEA-EAAEEKAEAAE 1370
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 105-321 9.14e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 38.18  E-value: 9.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 105 KLKVSEEEKQRIKQDVESLMEKhnvlekgfLKEKEQEAisFQDRYKELQEKHKQELEDMRKaghealsiivDEYKALLQS 184
Cdd:pfam17380 403 KVKILEEERQRKIQQQKVEMEQ--------IRAEQEEA--RQREVRRLEEERAREMERVRL----------EEQERQQQV 462

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 185 SVKQQVEAIEKQYISAIEKQAHKcEELLNAQHQRLLE--MLDTEKELLKEKIKEALIQQSQE--QKEILEkclEEERQRN 260
Cdd:pfam17380 463 ERLRQQEEERKRKKLELEKEKRD-RKRAEEQRRKILEkeLEERKQAMIEEERKRKLLEKEMEerQKAIYE---EERRREA 538

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370462245 261 KEALVSAAKLEKEAVKDAVLKVVEEERKNLEkahAEERELWKTEHAKDQEKVSQEIQKAIQ 321
Cdd:pfam17380 539 EEERRKQQEMEERRRIQEQMRKATEERSRLE---AMEREREMMRQIVESEKARAEYEATTP 596
Mitofilin pfam09731
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...
 83-295 9.79e-03

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.


Pssm-ID: 430783 [Multi-domain]  Cd Length: 618  Bit Score: 38.20  E-value: 9.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245  83 SEDPGANVSNIQLQQKISSLEIKLKV-SEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELE 161
Cdd:pfam09731 225 PEHLDNVEEKVEKAQSLAKLVDQYKElVASERIVFQQELVSIFPDIIPVLKEDNLLSNDDLNSLIAHAHREIDQLSKKLA 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462245 162 DMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEK----QAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEA 237
Cdd:pfam09731 305 ELKKREEKHIERALEKQKEELDKLAEELSARLEEVRAADEAQlrleFEREREEIRESYEEKLRTELERQAEAHEEHLKDV 384

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370462245 238 LIQQSQE----QKEILEKCLEEERQRNKEALvSAAKLEKEAVKDAVLKVVEEERKNLeKAHA 295
Cdd:pfam09731 385 LVEQEIElqreFLQDIKEKVEEERAGRLLKL-NELLANLKGLEKATSSHSEVEDENR-KAQQ 444
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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