|
Name |
Accession |
Description |
Interval |
E-value |
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
2804-3004 |
2.00e-109 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 347.05 E-value: 2.00e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2804 FQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA 2883
Cdd:pfam05010 1 YSQKDMDAALEKARNEIEEKELEINELKAKYEELRRENLEMRKIVAEFEKTIAQMIEEKQKQKELEHAEIQKVLEEKDQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2884 LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQ 2963
Cdd:pfam05010 81 LADLNSVEKSFSDLFKRYEKQKEVISGYKKNEESLKKCAQDYLARIKKEEQRYQALKAHAEEKLDQANEEIAQVRSKAKA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456153 2964 EQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 3004
Cdd:pfam05010 161 ETAALQASLRKEQMKVQSLERQLEQKTKENEELTKICDELI 201
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
23-487 |
2.01e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.72 E-value: 2.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 23 PPNPEPTQRTLSAQTPRSA-QPPGNSQNIKRKQQDTPGSPdhrdASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRK 101
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPApRPSEPAVTSRARRPDAPPQS----ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP 2631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 102 DPQGARGPEGSLLPSPPPSQEREHPSssmpfaecPPEGCLASPAAAPEDGPQTQSPRREPAPnapgdiaaafPAERDSST 181
Cdd:PHA03247 2632 SPAANEPDPHPPPTVPPPERPRDDPA--------PGRVSRPRRARRLGRAAQASSPPQRPRR----------RAARPTVG 2693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 182 PYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEA------------ 249
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPttagppapappa 2773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 250 --AGGFPPAESRQGVASVQVT------PEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTD 321
Cdd:PHA03247 2774 apAAGPPRRLTRPAVASLSESreslpsPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 322 -------DLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGH 394
Cdd:PHA03247 2854 gsvapggDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 395 PQTGMRGTKPNQVVCVAAGGQPEGGLPvSPEPSLLTPTEEAHPaSSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSAD 474
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAVP-QPWLGALVPGRVAVP-RFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSL 3011
|
490
....*....|...
gi 1370456153 475 AAKEVVDAGLVGL 487
Cdd:PHA03247 3012 ALHEETDPPPVSL 3024
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2737-3002 |
6.04e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 6.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2737 AQKLQEElefaIMRIEALKLA---RQIALASRSHQDAKREAAHPTD----VSISKTALYSRigTAEVEKPAGLLFQQPDL 2809
Cdd:PTZ00121 1120 AKKKAED----ARKAEEARKAedaRKAEEARKAEDAKRVEIARKAEdarkAEEARKAEDAK--KAEAARKAEEVRKAEEL 1193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2810 DSALQIARAEIITK---EREVSEWKdKYEESRR-----EVMEMRKIVAEYEKTIAQMIEDEQR---EKSVSHQTVQQLVL 2878
Cdd:PTZ00121 1194 RKAEDARKAEAARKaeeERKAEEAR-KAEDAKKaeavkKAEEAKKDAEEAKKAEEERNNEEIRkfeEARMAHFARRQAAI 1272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2879 EKEQAL-AD--LNSVEKSLADLFRRYEKMKEVLEGFRKNEEvlKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2955
Cdd:PTZ00121 1273 KAEEARkADelKKAEEKKKADEAKKAEEKKKADEAKKKAEE--AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA 1350
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1370456153 2956 QVRGKaqqeqaahQASLRKEQLRVDALERTLEQKNKEIEELTKICDE 3002
Cdd:PTZ00121 1351 EAEAA--------ADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEE 1389
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2802-3008 |
8.80e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.15 E-value: 8.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2802 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQM-IEDEQREKSVshQTVQQLV 2877
Cdd:PRK03918 184 FIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeIEELeKELESLEGSK--RKLEEKI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2878 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANA----- 2952
Cdd:PRK03918 262 RELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDE-LREIEKRLSRLEEEINGIEERIKELEEkeerl 340
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370456153 2953 ------------EIAQVRGKAQQEQAAHQASLRKEQLR-------VDALERTLEQKNKEIEELTKICDELIAKMG 3008
Cdd:PRK03918 341 eelkkklkelekRLEELEERHELYEEAKAKKEELERLKkrltgltPEKLEKELEELEKAKEEIEEEISKITARIG 415
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2809-3002 |
1.55e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2809 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQMIEDEQREKsvshqtvQQLVLEKEQALA 2885
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKElyaLANEISRLEQQK-------QILRERLANLER 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2886 DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH---AEEKLDRANAEIAQVRGKAQ 2962
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIA 396
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1370456153 2963 qeqaahqaSLRKEQLRVDA----LERTLEQKNKEIEELTKICDE 3002
Cdd:TIGR02168 397 --------SLNNEIERLEArlerLEDRRERLQQEIEELLKKLEE 432
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2729-3005 |
3.67e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.10 E-value: 3.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2729 AEKnpplfAQKLQEELEfaimRIEALKLARQIALASRSHQDAKREAAhptdvsisktalysrigtaevekpagllfqqpD 2808
Cdd:COG1196 212 AER-----YRELKEELK----ELEAELLLLKLRELEAELEELEAELE--------------------------------E 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2809 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKsvshQTVQQLVLEKEQALADLN 2888
Cdd:COG1196 251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEELA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2889 SVEKSLADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAH 2968
Cdd:COG1196 327 ELEEELEEL---EEELEELEEELEEAEEELEEAEAE-LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270
....*....|....*....|....*....|....*..
gi 1370456153 2969 QASLRKEQLRVDALERTLEQKNKEIEELTKICDELIA 3005
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2809-3007 |
4.36e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 4.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2809 LDSALQIARAEIITKE-REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQmiedeqreksvshqtvqqlVLEKEQALADL 2887
Cdd:COG4717 47 LLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEKEEEYAELQEE-------------------LEELEEELEEL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2888 NSVEKSLADLFRRYEKMKEVLEGFRKNEEvLKRCAQEYLSRVKKEEQRYQALKvHAEEKLDRANAEIAQVRGKAQQEQAA 2967
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEA-LEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQ 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1370456153 2968 HQASLRKE-----------QLRVDALERTLEQKNKEIEELTKICDELIAKM 3007
Cdd:COG4717 186 LSLATEEElqdlaeeleelQQRLAELEEELEEAQEELEELEEELEQLENEL 236
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2737-3006 |
7.95e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 7.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2737 AQKLQEELEFAIMRIEALKLARQI---ALASRSHQDAKREAAHPTDVSISKTALYSRigTAEVEKPAGLLFQQPDLDSAL 2813
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAkkkADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAKKADEAKKAEEKKKAD 1549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2814 QIARAEIITKEREVSewkdKYEESRREvmEMRKIVAEYEKTIAQMIEdEQREKSVSHQTVQQLVLEKEQALADlnSVEKS 2893
Cdd:PTZ00121 1550 ELKKAEELKKAEEKK----KAEEAKKA--EEDKNMALRKAEEAKKAE-EARIEEVMKLYEEEKKMKAEEAKKA--EEAKI 1620
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2894 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYqalKVHAEEKLDRANAEiaqvRGKAQQEQAAHQASLR 2973
Cdd:PTZ00121 1621 KAEELKKAEEEKKKVEQLKKKEAEEKKKAEE----LKKAEEEN---KIKAAEEAKKAEED----KKKAEEAKKAEEDEKK 1689
|
250 260 270
....*....|....*....|....*....|...
gi 1370456153 2974 KEQlrvdALERTLEQKNKeIEELTKICDELIAK 3006
Cdd:PTZ00121 1690 AAE----ALKKEAEEAKK-AEELKKKEAEEKKK 1717
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2748-2998 |
2.20e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.99 E-value: 2.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2748 IMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIgtAEVEKpaglLFQQPDLDSALQIARAEiitKEREV 2827
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI--EEVMK----LYEEEKKMKAEEAKKAE---EAKIK 1621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2828 SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA--LADLNSVEKSLADLFRRYEKMK 2905
Cdd:PTZ00121 1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeAKKAEEDEKKAAEALKKEAEEA 1701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2906 EVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAEEKLDRANAEIAQVR-------GKAQQEQAAHQASLRKEQLR 2978
Cdd:PTZ00121 1702 KKAEELKKKEAEEKKKAEEL--KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDeeekkkiAHLKKEEEKKAEEIRKEKEA 1779
|
250 260
....*....|....*....|..
gi 1370456153 2979 V--DALERTLEQKNKEIEELTK 2998
Cdd:PTZ00121 1780 VieEELDEEDEKRRMEVDKKIK 1801
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2817-2996 |
2.75e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 2.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2817 RAEIITKEREVseWKDKYEESRREVMEMRKIVAEYEktiaQMIEDEQREKSVSHQTVQQLVL---EKEQALADLNSVEKS 2893
Cdd:TIGR02168 219 KAELRELELAL--LVLRLEELREELEELQEELKEAE----EELEELTAELQELEEKLEELRLevsELEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2894 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKaqqeqaahqasLR 2973
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE-----------LE 361
|
170 180
....*....|....*....|...
gi 1370456153 2974 KEQLRVDALERTLEQKNKEIEEL 2996
Cdd:TIGR02168 362 ELEAELEELESRLEELEEQLETL 384
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2738-3006 |
3.08e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 3.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2738 QKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAhptdvsisKTALYSRigTAEVEkpagllfqqpDLDSALQIAR 2817
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEEL--------RLELEEL--ELELE----------EAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2818 AEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKsvshQTVQQLVLEKEQALADLNSVEKSLADL 2897
Cdd:COG1196 295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE----EELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2898 FRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG--KAQQEQAAHQASLRKE 2975
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEleEEEEEEEEALEEAAEE 450
|
250 260 270
....*....|....*....|....*....|.
gi 1370456153 2976 QLRVDALERTLEQKNKEIEELTKICDELIAK 3006
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAE 481
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2817-3006 |
3.28e-06 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 51.84 E-value: 3.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2817 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMiEDEQreksvshQTvQQLVLEKEQALadlnsVEKsLAD 2896
Cdd:COG1340 80 RDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERL-EWRQ-------QT-EVLSPEEEKEL-----VEK-IKE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2897 LFRRYEKMKEVLEGFRKNEEVLKRCAQEylsRVKKEEQRyQALKVHAEEkLDRANAEIAQVRGKAQqeqaahqaSLRKE- 2975
Cdd:COG1340 145 LEKELEKAKKALEKNEKLKELRAELKEL---RKEAEEIH-KKIKELAEE-AQELHEEMIELYKEAD--------ELRKEa 211
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456153 2976 ----------QLRVDALERTLEQKNKEIEELTKICDELIAK 3006
Cdd:COG1340 212 delhkeiveaQEKADELHEEIIELQKELRELRKELKKLRKK 252
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2737-2989 |
3.85e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.75 E-value: 3.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2737 AQKLQE--------ELEFAIMRIEALK-----LARQIALASRSHQDAKREAAHpTDVSISKT------------------ 2785
Cdd:TIGR02168 212 AERYKElkaelrelELALLVLRLEELReeleeLQEELKEAEEELEELTAELQE-LEEKLEELrlevseleeeieelqkel 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2786 -ALYSRIGTAEV------EKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM 2858
Cdd:TIGR02168 291 yALANEISRLEQqkqilrERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2859 iEDEQREKSVSHQTVQQLVLEKEQALADLNS----VEKSLADLFRRYEKMKEVLEGFRKN-EEVLKRCAQEYLSRVKKEE 2933
Cdd:TIGR02168 371 -ESRLEELEEQLETLRSKVAQLELQIASLNNeierLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEEL 449
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456153 2934 QRYQALKVHAEEKLDRANAEIAQVRgkaqQEQAAHQASLRKEQLRVDALERTLEQK 2989
Cdd:TIGR02168 450 EELQEELERLEEALEELREELEEAE----QALDAAERELAQLQARLDSLERLQENL 501
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2740-2958 |
5.81e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 5.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2740 LQEELEFAIMRIEALKlaRQIALASRSHQDAKREAAHpTDVSISKT-----ALYSRIGTAEVEKPAgllfqqpdLDSALQ 2814
Cdd:TIGR02169 292 VKEKIGELEAEIASLE--RSIAEKERELEDAEERLAK-LEAEIDKLlaeieELEREIEEERKRRDK--------LTEEYA 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2815 IARAEIITKEREVSEWKDKYEESRREVMEMRKivaEYEKTIAQMiEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSL 2894
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYRE---KLEKLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKI 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456153 2895 ADLfrrYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYQALKvhaeEKLDRANAEIAQVR 2958
Cdd:TIGR02169 437 NEL---EEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLK----EEYDRVEKELSKLQ 489
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2817-2998 |
6.12e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 6.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2817 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM---IEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKS 2893
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2894 LADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLR 2973
Cdd:TIGR02168 756 LTEL---EAEIEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180
....*....|....*....|....*...
gi 1370456153 2974 K---EQLRVDALERTLEQKNKEIEELTK 2998
Cdd:TIGR02168 832 RiaaTERRLEDLEEQIEELSEDIESLAA 859
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2816-3005 |
7.35e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.99 E-value: 7.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2816 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED-----EQREKSVSHQTVQQ---------LVLEKE 2881
Cdd:TIGR02169 154 ERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQlerlrREREKAERYQALLKekreyegyeLLKEKE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2882 QALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKE-EQRYQALKvhaeEKLDRANAEIAQVRGK 2960
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVK----EKIGELEAEIASLERS 309
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1370456153 2961 AQQEQAAHQAS---LRKEQLRVDALERTLEQKNKEIEELTKICDELIA 3005
Cdd:TIGR02169 310 IAEKERELEDAeerLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2802-3004 |
9.95e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 9.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2802 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQ-------REKSVSHQTVQ 2874
Cdd:TIGR02169 228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlrvkekiGELEAEIASLE 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2875 QLVLEKEQALADLnsvEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEkLDRANAEi 2954
Cdd:TIGR02169 308 RSIAEKERELEDA---EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE-VDKEFAE- 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2955 aqvrgkaqqeqaahqasLRKEQlrvDALERTLEQKNKEIEELTKICDELI 3004
Cdd:TIGR02169 383 -----------------TRDEL---KDYREKLEKLKREINELKRELDRLQ 412
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
2805-3006 |
1.16e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2805 QQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIaqmiedEQREKSVSHQTVQQLVLEKEQAL 2884
Cdd:COG4942 49 EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL------EAQKEELAELLRALYRLGRQPPL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2885 ADLNSVEkSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQE 2964
Cdd:COG4942 123 ALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRA-DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKL 200
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1370456153 2965 qaahqasLRKEQLRVDALERTLEQKNKEIEELTKICDELIAK 3006
Cdd:COG4942 201 -------LARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2795-3003 |
1.31e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.22 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2795 EVEKPAGLLFQQPdldSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQ 2874
Cdd:PRK03918 311 EIEKRLSRLEEEI---NGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2875 QLVLE-------KEQALADLNSVEKSLADLFRRYEKMKEVLEGFRK------------NEEVLKRCAQEYLSRVKKEEQR 2935
Cdd:PRK03918 388 KLEKEleelekaKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370456153 2936 YQALKvHAEEKLDRANAEIAQVRGKAQQ--EQAAHQASLR--KEQLRVDALERtLEQKNKEIEELTKICDEL 3003
Cdd:PRK03918 468 LKEIE-EKERKLRKELRELEKVLKKESEliKLKELAEQLKelEEKLKKYNLEE-LEKKAEEYEKLKEKLIKL 537
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2817-3005 |
2.47e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 2.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2817 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAE------YEKTIAQMIEDEQREKSVSHQTV----------------- 2873
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKeselikLKELAEQLKELEEKLKKYNLEELekkaeeyeklkeklikl 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2874 --QQLVLEKEqaLADLNSVEKSLADLFRRYEKMKEVL---------EGFRKNEEV------LKRCAQEYL------SRVK 2930
Cdd:PRK03918 538 kgEIKSLKKE--LEKLEELKKKLAELEKKLDELEEELaellkeleeLGFESVEELeerlkeLEPFYNEYLelkdaeKELE 615
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2931 KEEQRYQALK---VHAEEKLDRANAEIAQVRGK----AQQEQAAHQASLRKEQLRvdaLERTLEQKNKEIEELTKICDEL 3003
Cdd:PRK03918 616 REEKELKKLEeelDKAFEELAETEKRLEELRKEleelEKKYSEEEYEELREEYLE---LSRELAGLRAELEELEKRREEI 692
|
..
gi 1370456153 3004 IA 3005
Cdd:PRK03918 693 KK 694
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
2184-2571 |
2.95e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 50.07 E-value: 2.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2184 SGENLASETKTESAKTEGPSpalleETPLEPAVGPKAacPLDSESAEGVVPPASGggrvQNSPPVGRKtlPLTTapEAGE 2263
Cdd:PTZ00449 492 SKKKLAPIEEEDSDKHDEPP-----EGPEASGLPPKA--PGDKEGEEGEHEDSKE----SDEPKEGGK--PGET--KEGE 556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2264 VTPSDSGGQEDSPAK--GLSVRLEFDySEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPeKLDNTPASP--PR 2339
Cdd:PTZ00449 557 VGKKPGPAKEHKPSKipTLSKKPEFP-KDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIP-KSPKRPESPksPK 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2340 SPAEPNDiPIAKgtytfdidkwDDPNFNPFSSTSKMQESPKLPqqsynFDPDTCDESVDPFktssktpsspskspasfei 2419
Cdd:PTZ00449 635 RPPPPQR-PSSP----------ERPEGPKIIKSPKPPKSPKPP-----FDPKFKEKFYDDY------------------- 679
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2420 pasameangvdgdgLNKPAKKKKTPLKTMVEDVMSVCSLFDTFRVKKSPKRSPLSDPPSQdPTPAATPETPPvisavvHA 2499
Cdd:PTZ00449 680 --------------LDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKL-PRDEEFPFEPI------GD 738
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370456153 2500 TDEEKlavtnqkwtcmtvdlEADKQDYPQPSDLSTFVNETKFSSPTEGKQLCSQLDPHSASENPAPREPKAR 2571
Cdd:PTZ00449 739 PDAEQ---------------PDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEAMKR 795
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
106-687 |
3.14e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.94 E-value: 3.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 106 ARGPEGSLLPSPPPSQerehPSSSMPFAEC---PPEGCLASPAAAPEDGPQTQSPRrepapnAPGDIAAAFPAerdsstP 182
Cdd:PHA03247 2548 AGDPPPPLPPAAPPAA----PDRSVPPPRPaprPSEPAVTSRARRPDAPPQSARPR------APVDDRGDPRG------P 2611
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 183 YQEIAAVPSAGRERQPKEEGQKSSFSFSSGidqSPGMSPVPLRePMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGV 262
Cdd:PHA03247 2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPH---PPPTVPPPER-PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRA 2687
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 263 ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAP-RASDRERGQGEAPPqyltddleflrachlPRSNSGAAPE 341
Cdd:PHA03247 2688 ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAaRQASPALPAAPAPP---------------AVPAGPATPG 2752
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 342 AEVNAASQESCQQPVGAYLPHAelPWGLPSPALVPEAGGSGKEALDTIDVQGHPqtgmrgTKPNQVVCVAAGGQPEGGLP 421
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAA--PAAGPPRRLTRPAVASLSESRESLPSPWDP------ADPPAAVLAPAAALPPAASP 2824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 422 VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDaglvglerqvsdlgskgehp 501
Cdd:PHA03247 2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVR-------------------- 2884
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 502 egdpgEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSP 581
Cdd:PHA03247 2885 -----RLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 582 AVAKEGSRSPGD---------SPGGKEEAPEPP-----DGGDPGNLQGEDSQAFSSKRDP-EVGKDELSKPSSDAESRDH 646
Cdd:PHA03247 2960 PQPWLGALVPGRvavprfrvpQPAPSREAPASStppltGHSLSRVSSWASSLALHEETDPpPVSLKQTLWPPDDTEDSDA 3039
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1370456153 647 PSSHSAQPPRKGGAG---HTDGPHSQTAEADASGLPHKLGEEDP 687
Cdd:PHA03247 3040 DSLFDSDSERSDLEAldpLPPEPHDPFAHEPDPATPEAGARESP 3083
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2813-2954 |
3.91e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.68 E-value: 3.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2813 LQIARAEIITKEREVSEWKDKYEESRREVMEMRKI--VAEYEKtiaqmIEDEQREKSVSHQTVQQlvlEKEQALADLNSV 2890
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKysEEEYEE-----LREEYLELSRELAGLRA---ELEELEKRREEI 692
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370456153 2891 EKSLADLFRRYEKMKEVlegfRKNEEVLKRcAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEI 2954
Cdd:PRK03918 693 KKTLEKLKEELEEREKA----KKELEKLEK-ALERVEELREKVKKYKALlKERALSKVGEIASEI 752
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2835-2998 |
4.20e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 48.75 E-value: 4.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2835 EESRREVMEMRKIVAEYEKTIAQmIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKN 2914
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREE-LEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2915 EEVLkrcaQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQvrgkaqqeqaahqaslRKEQLRvdALERTLEQKNKEIE 2994
Cdd:COG4372 110 AEEL----QEELEELQKERQDLEQQRKQLEAQIAELQSEIAE----------------REEELK--ELEEQLESLQEELA 167
|
....
gi 1370456153 2995 ELTK 2998
Cdd:COG4372 168 ALEQ 171
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2727-2930 |
4.21e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 4.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2727 DLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDvsiSKTALYSRIGTAEvEKPAGLLFQQ 2806
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE---ELQRLSEELADLN-AAIAGIEAKI 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2807 PDLDSALQIARAEIITKEREVSEWKDKYEESRRevmEMRKIVAEYEKtiaqmIEDEQREKS-----------VSHQTV-- 2873
Cdd:TIGR02169 437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ---ELYDLKEEYDR-----VEKELSKLQrelaeaeaqarASEERVrg 508
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370456153 2874 ---QQLVLEkeqalADLNSVEKSLADLFR---RYEKMKEVLEGFR------KNEEVLKRCAqEYLSRVK 2930
Cdd:TIGR02169 509 graVEEVLK-----ASIQGVHGTVAQLGSvgeRYATAIEVAAGNRlnnvvvEDDAVAKEAI-ELLKRRK 571
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2817-3009 |
4.87e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.98 E-value: 4.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2817 RAEIITkerEVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE------DEQREKSVSHQTVQQLVLEKEQALADLNSV 2890
Cdd:COG1340 31 RDELNE---ELKELAEKRDELNAQVKELREEAQELREKRDELNEkvkelkEERDELNEKLNELREELDELRKELAELNKA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2891 EKSLADLFRRYEKMK-----EVLeGFRKNEEVLKRCAQ--EYLSRVKKEEQ----------RYQALKVHAE--------- 2944
Cdd:COG1340 108 GGSIDKLRKEIERLEwrqqtEVL-SPEEEKELVEKIKEleKELEKAKKALEkneklkelraELKELRKEAEeihkkikel 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456153 2945 -EKLDRANAEIAQVRGKaqqeqaahQASLRKEqlrVDALERTLEQKNKEIEELTKICDELIAKMGK 3009
Cdd:COG1340 187 aEEAQELHEEMIELYKE--------ADELRKE---ADELHKEIVEAQEKADELHEEIIELQKELRE 241
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
2738-2998 |
5.30e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 48.80 E-value: 5.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2738 QKLQEELEFAIMRIEALKLARQIALA--SRSHQDAKREaahpTDVSIsktalysRIGTAEVEKpagllfQQPDLDSALQI 2815
Cdd:COG5185 296 EKIAEYTKSIDIKKATESLEEQLAAAeaEQELEESKRE----TETGI-------QNLTAEIEQ------GQESLTENLEA 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2816 ARAEII---------TKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED---EQREKSVSHQT-VQQLVLEKEQ 2882
Cdd:COG5185 359 IKEEIEnivgevelsKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDtlkAADRQIEELQRqIEQATSSNEE 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2883 ALADLNSVEKSLADLFRR---------YEKMKEVLEGFRKNEEVLKRcaqeylsRVKKEEQRYQALKVHAEEKLDRANAE 2953
Cdd:COG5185 439 VSKLLNELISELNKVMREadeesqsrlEEAYDEINRSVRSKKEDLNE-------ELTQIESRVSTLKATLEKLRAKLERQ 511
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1370456153 2954 IAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2998
Cdd:COG5185 512 LEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNA 556
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2803-2995 |
7.58e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.97 E-value: 7.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2803 LFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektIAQMIEDEQREKSVSHQTVQQLVLEKEQ 2882
Cdd:COG4372 37 LFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEE----LNEQLQAAQAELAQAQEELESLQEEAEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2883 ALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEIAQV---- 2957
Cdd:COG4372 113 LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALeQELQALSEAEAEQALDELlkea 192
|
170 180 190
....*....|....*....|....*....|....*....
gi 1370456153 2958 -RGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2995
Cdd:COG4372 193 nRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKL 231
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2812-2996 |
8.97e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 8.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2812 ALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI----------------VAEYEKTIAQmIEDEQREKSVSHQTVQQ 2875
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERrealqrlaeyswdeidVASAEREIAE-LEAELERLDASSDDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2876 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2955
Cdd:COG4913 690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD-RLEAAEDLARLELRALLEERFAAALGDAVERELR 768
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456153 2956 QvrgkaqqeqaahqaSLRKeqlRVDALERTLEQKNKEIEEL 2996
Cdd:COG4913 769 E--------------NLEE---RIDALRARLNRAEEELERA 792
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2750-3006 |
1.49e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2750 RIEALKLARQialASRSHQDAKR--------EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEII 2821
Cdd:PTZ00121 1225 KAEAVKKAEE---AKKDAEEAKKaeeernneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2822 TKEREV---SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALAD--LNSVEKSLAD 2896
Cdd:PTZ00121 1302 KKADEAkkkAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAekKKEEAKKKAD 1381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2897 LFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEE--KLDRANAEIAQVRgKAQQEQAAHQASLRK 2974
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKKKAEEDKKKADE-LKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEAK-KADEAKKKAEEAKKA 1459
|
250 260 270
....*....|....*....|....*....|...
gi 1370456153 2975 EQLRVDALE-RTLEQKNKEIEELTKiCDELIAK 3006
Cdd:PTZ00121 1460 EEAKKKAEEaKKADEAKKKAEEAKK-ADEAKKK 1491
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
92-494 |
1.70e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 92 VSPEVTEPRKDPQGARGPEGSLLPSP----PPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPG 167
Cdd:PRK07764 387 VAGGAGAPAAAAPSAAAAAPAAAPAPaaaaPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 168 DIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQS--PGMSPVPLREPMKAPLCGEGDQPGGFESQ 245
Cdd:PRK07764 467 APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERwpEILAAVPKRSRKTWAILLPEATVLGVRGD 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 246 E---KEAAGGFPPAESRQGVASV-----------QVTPEA-----PAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASD 306
Cdd:PRK07764 547 TlvlGFSTGGLARRFASPGNAEVlvtalaeelggDWQVEAvvgpaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAA 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 307 RERGQGEAPPQYLTDDleflRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEAL 386
Cdd:PRK07764 627 PAPAGAAAAPAEASAA----PAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA 702
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 387 DTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSllTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSK 466
Cdd:PRK07764 703 PAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP--EPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
|
410 420
....*....|....*....|....*...
gi 1370456153 467 AGMPVSADAAKEVVDAGLVGLERQVSDL 494
Cdd:PRK07764 781 EEEEMAEDDAPSMDDEDRRDAEEVAMEL 808
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2814-2988 |
1.90e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 1.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2814 QIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQ-TVQQLVLEKEQALADLNSVEK 2892
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlQLLPLYQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2893 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQE--------------YLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVR 2958
Cdd:COG4717 147 RLEELEERLEELRELEEELEELEAELAELQEEleelleqlslateeELQDLAEELEELQQRLAELEEELEEAQEELEELE 226
|
170 180 190
....*....|....*....|....*....|
gi 1370456153 2959 GKAQQEqaahqaslrKEQLRVDALERTLEQ 2988
Cdd:COG4717 227 EELEQL---------ENELEAAALEERLKE 247
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2814-3006 |
3.51e-04 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 45.68 E-value: 3.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2814 QIARAEIITKEREvsewkdkyEESRREVMEMRKivaEYEKTIAQMIEDEQREKSVSHQTVQQLV-----------LEKEQ 2882
Cdd:pfam13868 27 QIAEKKRIKAEEK--------EEERRLDEMMEE---ERERALEEEEEKEEERKEERKRYRQELEeqieereqkrqEEYEE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2883 ALADLNSV--------EKSLADLFRRYEKMKEVLEGFRK-NEEVLKRCAQEYLsRVKKEEQRYQAlkvHAEEKLDRANAE 2953
Cdd:pfam13868 96 KLQEREQMdeiveriqEEDQAEAEEKLEKQRQLREEIDEfNEEQAEWKELEKE-EEREEDERILE---YLKEKAEREEER 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456153 2954 IAQVRGKAqqeqaahqaslRKEQLRVDALERTLEQKNKEIEELtkicDELIAK 3006
Cdd:pfam13868 172 EAEREEIE-----------EEKEREIARLRAQQEKAQDEKAER----DELRAK 209
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
257-621 |
4.78e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 4.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 257 ESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNS 336
Cdd:PRK07764 382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 337 GAAPEAEVNAASQESCQQPVGAYLPHAElPWGLPSPALVPEAGGSGKEAlDTID-------------------------- 390
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAAPA-PAAAPAAPAAPAAPAGADDA-ATLRerwpeilaavpkrsrktwaillpeat 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 391 ---------VQGHPQTGMRG--TKPN-----------------QVVCVAAGGQPEGGLPVSPEP-SLLTPTEEAHPASSL 441
Cdd:PRK07764 540 vlgvrgdtlVLGFSTGGLARrfASPGnaevlvtalaeelggdwQVEAVVGPAPGAAGGEGPPAPaSSGPPEEAARPAAPA 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 442 ASF--PAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGeh 519
Cdd:PRK07764 620 APAapAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAA-- 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 520 lnteQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARG---------PPGPTDGAKVHEDSTSPAVAKEGSRS 590
Cdd:PRK07764 698 ----PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPvplppepddPPDPAGAPAQPPPPPAPAPAAAPAAA 773
|
410 420 430
....*....|....*....|....*....|.
gi 1370456153 591 PGDSPGGKEEAPEPPDGGDPGNLQGEDSQAF 621
Cdd:PRK07764 774 PPPSPPSEEEEMAEDDAPSMDDEDRRDAEEV 804
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1542-2006 |
7.80e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.31 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1542 PTLREDERPEGPGAAWPGLE----GQAYSQLERSRQELASGLPS-PAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSG 1616
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAqASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEP 2710
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1617 KQHQETSACDSPHGEDGPGDFAH----TGVPGHVPRSTCAPS----PQREVLTVPEANSEPWTLDTLGGERR--PGVTAG 1686
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPalpaAPAPPAVPAGPATPGgparPARPPTTAGPPAPAPPAAPAAGPPRRltRPAVAS 2790
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1687 ILEMRNALGNQSTPAPPTGEV-ADTPLEPGKVAGAAGEAEGDITLSTAEtqACASGDLPEAGTTRTFSVVAGDLVLPGSC 1765
Cdd:PHA03247 2791 LSESRESLPSPWDPADPPAAVlAPAAALPPAASPAGPLPPPTSAQPTAP--PPPPGPPPPSLPLGGSVAPGGDVRRRPPS 2868
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1766 QDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPagdgkvcvSSPPEPDETHDPKLQHLAPEELHTDRESPRPG 1845
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP--------PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1846 PSMLPSVPKKDAPRVMDKVtSDETRGAEGTESSPVADDIIQPAAPAdLESPTLAASSYHGDVVGQVSTdlIAQSISPAAA 1925
Cdd:PHA03247 2941 PPLAPTTDPAGAGEPSGAV-PQPWLGALVPGRVAVPRFRVPQPAPS-REAPASSTPPLTGHSLSRVSS--WASSLALHEE 3016
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1926 HAGLPPSAAEHIVSPSAPAGDRVEASTPScpDPAKDLSRSSDSEeafeTPESTTPVKAPPAPPPPPPEVIPEPEVSTQPP 2005
Cdd:PHA03247 3017 TDPPPVSLKQTLWPPDDTEDSDADSLFDS--DSERSDLEALDPL----PPEPHDPFAHEPDPATPEAGARESPSSQFGPP 3090
|
.
gi 1370456153 2006 P 2006
Cdd:PHA03247 3091 P 3091
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2816-2949 |
8.64e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.13 E-value: 8.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2816 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTI----AQMIE-----DEQREKSVS-HQTVQqlvlEKEQALA 2885
Cdd:COG1340 151 KAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAqelhEEMIElykeaDELRKEADElHKEIV----EAQEKAD 226
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456153 2886 DLNsveKSLADLFRRYEKMKEVLEGFRKNEEVLKRcaqeylsrvKKEEQRYQALKVHAEEKLDR 2949
Cdd:COG1340 227 ELH---EEIIELQKELRELRKELKKLRKKQRALKR---------EKEKEELEEKAEEIFEKLKK 278
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
23-318 |
9.69e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 9.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 23 PPNPEPTQRTLSAQTPRSAQPPGNSQNIKrkqqdTPGSPDHRDASSIGSVGLGGFCTASESSASLDP----CLVSPEVTE 98
Cdd:PHA03307 67 PPTGPPPGPGTEAPANESRSTPTWSLSTL-----APASPAREGSPTPPGPSSPDPPPPTPPPASPPPspapDLSEMLRPV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 99 PRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERD 178
Cdd:PHA03307 142 GSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 179 SSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAES 258
Cdd:PHA03307 222 PAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPS 301
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456153 259 RQGV--------ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPI--------PQDPAPRASDRERGQGEAPPQY 318
Cdd:PHA03307 302 SPGSgpapssprASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPsrspspsrPPPPADPSSPRKRPRPSRAPSS 377
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1767-2054 |
9.94e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 9.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1767 DPACSDKAPGMEGTAAlhgDSPARPQQaKEQPGPERPIPAGDGKVcVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGP 1846
Cdd:PHA03307 46 DSAELAAVTVVAGAAA---CDRFEPPT-GPPPGPGTEAPANESRS-TPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPT 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1847 SMLPSVPKKDAPRVmdkvtSDETRGAEGTESSPVADDIIQPAAPADLESPTlaASSYHGDVVGQVSTDLIAQSISPAAAh 1926
Cdd:PHA03307 121 PPPASPPPSPAPDL-----SEMLRPVGSPGPPPAASPPAAGASPAAVASDA--ASSRQAALPLSSPEETARAPSSPPAE- 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1927 agLPPSAAEHIVSPSAPAGDRVEASTPSCPDP------AKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEV 2000
Cdd:PHA03307 193 --PPPSTPPAAASPRPPRRSSPISASASSPAPapgrsaADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1370456153 2001 STQPP-PEEPGCGSE----TVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 2054
Cdd:PHA03307 271 EASGWnGPSSRPGPAssssSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST 329
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
240-714 |
1.03e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 240 GGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAqqgtesSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPP--- 316
Cdd:PHA03307 17 GGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAA------VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTptw 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 317 QYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGkealdtidvqghpq 396
Cdd:PHA03307 91 SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAG-------------- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 397 tgmrgtkpnqvvcvAAGGQPEGGLPVSPEPSLLTPTEEAH---PASSLASFPAAQIPIAVEEPGSS-SRESVSKAGMPVS 472
Cdd:PHA03307 157 --------------ASPAAVASDAASSRQAALPLSSPEETaraPSSPPAEPPPSTPPAAASPRPPRrSSPISASASSPAP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 473 ADAAKEVVDAG-----LVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQShevqpgvpppplpkEQSHEVQP 547
Cdd:PHA03307 223 APGRSAADDAGasssdSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSS--------------RPGPASSS 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 548 GAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDP 627
Cdd:PHA03307 289 SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 628 EvgkdelskPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIW 707
Cdd:PHA03307 369 P--------RPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSGEPW 440
|
....*..
gi 1370456153 708 EGSGLQP 714
Cdd:PHA03307 441 PGSPPPP 447
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2816-2995 |
1.73e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 43.37 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2816 ARAEIITKEREVSEWKDKYEEsrREVMEMRKIvAEYEKTIAQ---MIEDEQREKSVSHQTVQQLVL-----------EKE 2881
Cdd:pfam13868 128 LREEIDEFNEEQAEWKELEKE--EEREEDERI-LEYLKEKAEreeEREAEREEIEEEKEREIARLRaqqekaqdekaERD 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2882 QALADLNSVE-------KSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAE-EKLDRANAE 2953
Cdd:pfam13868 205 ELRAKLYQEEqerkerqKEREEAEKKARQRQELQQAREEQIELKERRLAEE--AEREEEEFERMLRKQAEdEEIEQEEAE 282
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1370456153 2954 iaQVRGKAQQEQAAHQASLR-KEQLRVDALERTLEQKNKEIEE 2995
Cdd:pfam13868 283 --KRRMKRLEHRRELEKQIEeREEQRAAEREEELEEGERLREE 323
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2731-2923 |
2.05e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2731 KNPPLFAQKLqEELEfaimriEALKLARQIALASRSHQDAKREA-AHPTDVSISKTALYSRIGTAEVEKPAGLLFQQpdl 2809
Cdd:COG4717 64 RKPELNLKEL-KELE------EELKEAEEKEEEYAELQEELEELeEELEELEAELEELREELEKLEKLLQLLPLYQE--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2810 dsaLQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNS 2889
Cdd:COG4717 134 ---LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAE 210
|
170 180 190
....*....|....*....|....*....|....
gi 1370456153 2890 VEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQ 2923
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2833-3009 |
2.13e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.35 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2833 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEgfR 2912
Cdd:COG4372 7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELE--E 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2913 KNEEVLKrcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRgkaqqeqaahqasLRKEQL--RVDALERTLEQKN 2990
Cdd:COG4372 85 LNEQLQA--AQAELAQAQEELESLQEEAEELQEELEELQKERQDLE-------------QQRKQLeaQIAELQSEIAERE 149
|
170
....*....|....*....
gi 1370456153 2991 KEIEELTKICDELIAKMGK 3009
Cdd:COG4372 150 EELKELEEQLESLQEELAA 168
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
2614-2995 |
2.46e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2614 DTSQESPVKSSPVRM-SESPTPCS-GSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQvpeKSSQKELEAMGLGTPSEA 2691
Cdd:pfam17380 181 RRRGNHSAFTRPGRPrTTTPMPVThATRFVPGIQMSTVAPKEVQGMPHTLAPYEKMERR---KESFNLAEDVTTMTPEYT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2692 IEITapeGSFASADALLSRLAHPVSLCGALDylEPDLAEKNPPLFAQKLQEELEFAIMRIEAlklARQIALASRSHQDA- 2770
Cdd:pfam17380 258 VRYN---GQTMTENEFLNQLLHIVQHQKAVS--ERQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEAEKARQAEm 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2771 KREA---AHPTDVSISKTALYSRIGTAEVEKPAGLLFQQpdlDSALQIARAEIItkEREVSEWKDKYEESRREVMEMRKi 2847
Cdd:pfam17380 330 DRQAaiyAEQERMAMERERELERIRQEERKRELERIRQE---EIAMEISRMREL--ERLQMERQQKNERVRQELEAARK- 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2848 vaeyektiaQMIEDEQREKSVSHQTVQQLVLEKEQaladlnsvEKSLADLFRRYEKMKEvLEGFRKNEEVLKRCAQEYLS 2927
Cdd:pfam17380 404 ---------VKILEEERQRKIQQQKVEMEQIRAEQ--------EEARQREVRRLEEERA-REMERVRLEEQERQQQVERL 465
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370456153 2928 RVKKEEQRYQALKVHAEEKlDRANAEiAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2995
Cdd:pfam17380 466 RQQEEERKRKKLELEKEKR-DRKRAE-EQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
2811-2998 |
2.46e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2811 SALQIARAEIITKE--REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM-------------IEDEQREKsvsHQTVQQ 2875
Cdd:TIGR04523 298 SDLNNQKEQDWNKElkSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLkkeltnsesenseKQRELEEK---QNEIEK 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2876 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKrcaQEYLSrVKKEEQRYQALKVHAEEKLDRANAEIA 2955
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ---QEKEL-LEKEIERLKETIIKNNSEIKDLTNQDS 450
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456153 2956 ----------QVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2998
Cdd:TIGR04523 451 vkeliiknldNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNE 503
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2817-3002 |
3.17e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.42 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2817 RAEIITKEREVsewkdkyEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTV--QQLVLEKEQALADLNSVEKSL 2894
Cdd:pfam02463 185 LAELIIDLEEL-------KLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLneERIDLLQELLRDEQEEIESSK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2895 ADLFRRYEKMKEVLEGFRKNEEVLK-----------RCAQEYLSRVKKEEQRYQALK--VHAEEKLDRANAEIAQVRGKA 2961
Cdd:pfam02463 258 QEIEKEEEKLAQVLKENKEEEKEKKlqeeelkllakEEEELKSELLKLERRKVDDEEklKESEKEKKKAEKELKKEKEEI 337
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1370456153 2962 QQEQAAHQASLRKEQL----RVDALERTLEQKNKEIEELTKICDE 3002
Cdd:pfam02463 338 EELEKELKELEIKREAeeeeEEELEKLQEKLEQLEEELLAKKKLE 382
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
88-305 |
3.45e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 88 DPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAA-PEDGPQTQSPRREPAPNAP 166
Cdd:PHA03307 52 AVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPsSPDPPPPTPPPASPPPSPA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 167 GDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLRE--PMKAPLCGEGDQPGGFES 244
Cdd:PHA03307 132 PDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAepPPSTPPAAASPRPPRRSS 211
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370456153 245 QEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRAS 305
Cdd:PHA03307 212 PISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEA 272
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1646-2036 |
4.17e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.00 E-value: 4.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1646 VPRSTCAPSPQREVLTV----PEANSEPWTLDTLGGERRPgvtagilemrNALGNQSTPAPPTGEVADTPlePGKVAGAA 1721
Cdd:PHA03247 2568 VPPPRPAPRPSEPAVTSrarrPDAPPQSARPRAPVDDRGD----------PRGPAPPSPLPPDTHAPDPP--PPSPSPAA 2635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1722 GEAEGDITLSTAETQ----ACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHgDSPARPQQAKEQ 1797
Cdd:PHA03247 2636 NEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPP-PPPPTPEPAPHA 2714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1798 PGPERPIPAGDGKVCVSSPPEPDETHDPKlqhlAPEELHTDRESPRPGPSMLPSVPKKDAPrvmdkvtsdetrgAEGTES 1877
Cdd:PHA03247 2715 LVSATPLPPGPAAARQASPALPAAPAPPA----VPAGPATPGGPARPARPPTTAGPPAPAP-------------PAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1878 SPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAhAGLPPSAAEHIVSPSAPAGDrVEASTPSCPD 1957
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-GPLPPPTSAQPTAPPPPPGP-PPPSLPLGGS 2855
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 1958 --PAKDLSRSSDSEEAFETPESTTPV-----KAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGS 2030
Cdd:PHA03247 2856 vaPGGDVRRRPPSRSPAAKPAAPARPpvrrlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935
|
....*.
gi 1370456153 2031 PFRPPS 2036
Cdd:PHA03247 2936 PPRPQP 2941
|
|
| YqiK |
COG2268 |
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]; |
2789-2960 |
4.74e-03 |
|
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 42.17 E-value: 4.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2789 SRIGTAEVEKpagllfqqpdlDSALQIARAEiitKEREVSEwkdkyEESRREVMEMRkiVAEYEKTIAQMIEDEQREKsv 2868
Cdd:COG2268 201 ARIAEAEAER-----------ETEIAIAQAN---REAEEAE-----LEQEREIETAR--IAEAEAELAKKKAEERREA-- 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2869 shqtvqqlvlEKEQALADLnSVEKsladlfRRYEKMKEV---LEGFRKNEEVLkrcAQEylSRVKKEEQRYQA---LKVH 2942
Cdd:COG2268 258 ----------ETARAEAEA-AYEI------AEANAEREVqrqLEIAEREREIE---LQE--KEAEREEAELEAdvrKPAE 315
|
170 180
....*....|....*....|..
gi 1370456153 2943 AE----EKLDRANAEIAQVRGK 2960
Cdd:COG2268 316 AEkqaaEAEAEAEAEAIRAKGL 337
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
2808-3007 |
5.14e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 5.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2808 DLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektiaqmIEDEQREKSVSHQTVQQLVLEKEQALA-- 2885
Cdd:COG1579 14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELED--------LEKEIKRLELEIEEVEARIKKYEEQLGnv 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2886 ----DLNSVEKSLADLfrryEKMKEVLEgfrknEEVLkrcaqeylsrvkkeeqryqalkvHAEEKLDRANAEIAQVRGKA 2961
Cdd:COG1579 86 rnnkEYEALQKEIESL----KRRISDLE-----DEIL-----------------------ELMERIEELEEELAELEAEL 133
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1370456153 2962 QQeqaahqaslRKEQLR--VDALERTLEQKNKEIEELTKICDELIAKM 3007
Cdd:COG1579 134 AE---------LEAELEekKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2873-2997 |
5.26e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 5.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2873 VQQLVLEKEQALADLNsvekSLADLFRRYEKMKEVLEGFRKNEEVLKRC---AQEYLS-RVKKEEQRYQALKVH---AEE 2945
Cdd:COG4913 213 VREYMLEEPDTFEAAD----ALVEHFDDLERAHEALEDAREQIELLEPIrelAERYAAaRERLAELEYLRAALRlwfAQR 288
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1370456153 2946 KLDRANAEIAQVRgkaqqeqaahqASLRKEQLRVDALERTLEQKNKEIEELT 2997
Cdd:COG4913 289 RLELLEAELEELR-----------AELARLEAELERLEARLDALREELDELE 329
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
2809-3003 |
5.94e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 5.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2809 LDSALQIARAEIitkeREVSEW-KDKYEESRREVMEMRKIVAEYEKtiAQMIEDEQREKSVSHQTVQQLVLEKEQALADL 2887
Cdd:COG3206 162 LEQNLELRREEA----RKALEFlEEQLPELRKELEEAEAALEEFRQ--KNGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2888 NSVEKSLADLFRRYEKMKEVLEGFRKNEEVlkrcaQEYLSRVKKEEQRYQALKVHAEEK---LDRANAEIAQVRGKAQQE 2964
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPELLQSPVI-----QQLRAQLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQE 310
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1370456153 2965 QAAHQASLRKE----QLRVDALERTLEQKNKEIEELTKICDEL 3003
Cdd:COG3206 311 AQRILASLEAElealQAREASLQAQLAQLEARLAELPELEAEL 353
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
2795-3004 |
7.63e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.75 E-value: 7.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2795 EVEKpagllfQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR--EKSVSHQT 2872
Cdd:PRK04778 307 YVEK------NSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERiaEQEIAYSE 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2873 VQqlvlekeqalADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLS-------RVKKEE-----QRYQALK 2940
Cdd:PRK04778 381 LQ----------EELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNklheikrYLEKSNlpglpEDYLEMF 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456153 2941 VHAEEKLDRANAEIAQVRgkaqqeqaahqaslrkeqLRVDALERTLEQKNKEIEELTKICDELI 3004
Cdd:PRK04778 451 FEVSDEIEALAEELEEKP------------------INMEAVNRLLEEATEDVETLEEETEELV 496
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2821-3009 |
7.88e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 7.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2821 ITKEREVSEWKDKYE----ESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQT-VQQLVLEKEQALADLNSVEKSLA 2895
Cdd:TIGR00618 245 LTQKREAQEEQLKKQqllkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKaVTQIEQQAQRIHTELQSKMRSRA 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2896 DLFRRY----------EKMKEVLEGFRKNEEVLKRCAQ------EYLSRVKKEEQRYQAL---KVHAEEKLDRANAEIAQ 2956
Cdd:TIGR00618 325 KLLMKRaahvkqqssiEEQRRLLQTLHSQEIHIRDAHEvatsirEISCQQHTLTQHIHTLqqqKTTLTQKLQSLCKELDI 404
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1370456153 2957 VRgKAQQEQAAHQASLRKEQLRVDALERT--LEQKNKEIEELTKICDELIAKMGK 3009
Cdd:TIGR00618 405 LQ-REQATIDTRTSAFRDLQGQLAHAKKQqeLQQRYAELCAAAITCTAQCEKLEK 458
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
2805-3008 |
8.00e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.95 E-value: 8.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2805 QQPDLDSalQIARAEIITK-EREVSEWKDKYEESRREVMEMRKIVAEYEKTI------AQMIEDEQREKSVSHQTVQQLV 2877
Cdd:PRK02224 490 EVEEVEE--RLERAEDLVEaEDRIERLEERREDLEELIAERRETIEEKRERAeelrerAAELEAEAEEKREAAAEAEEEA 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456153 2878 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKvhaeEKLDRanaeIAQV 2957
Cdd:PRK02224 568 EEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA----EKRER----KREL 639
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456153 2958 RGKAQQEqaahqaslRKEQLRVDA--LERTLEQKNKEIEELTKICDELIAKMG 3008
Cdd:PRK02224 640 EAEFDEA--------RIEEAREDKerAEEYLEQVEEKLDELREERDDLQAEIG 684
|
|
| |
