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Conserved domains on  [gi|1349665228|gb|AVH63026|]
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transmembrane protein of unknown function DUF6 [Nostoc sp. 'Peltigera membranacea cyanobiont' N6]

Protein Classification

DMT family transporter( domain architecture ID 11430850)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others

Gene Ontology:  GO:0016020|GO:0055085|GO:0022857
PubMed:  11432728
TCDB:  2.A.7

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 340-630 3.43e-33

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


:

Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 128.81  E-value: 3.43e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 340 FLGTASLLFALIPISLAPSLTKLCQQEIGANAVVFHRSWIATIVFALWNGLEafgsqqsdnePIEKKPFTSQEVWLLLAM 419
Cdd:COG0697     2 LRGILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLR----------GRRLPPLSRRDWLLLLLR 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 420 GTSAGT-YLLLWAWSLSQTSVANVALLSNLNSLFVALAGYLLFGRRFDNRFVIGLVIALGGAIAFELNKVQFATAQILGD 498
Cdd:COG0697    72 GLLGLAlAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLGD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 499 ALALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLvAFLEDRLLPYSWMGWFFIIFQALFCQVLGQGLLAY 578
Cdd:COG0697   152 LLALLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPL-ALLTGLPLPLSAAAWLALLYLGLFGTALAYLLWFR 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1349665228 579 SLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYLAQ 630
Cdd:COG0697   231 ALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 10-298 3.31e-30

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


:

Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 120.33  E-value: 3.31e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  10 ALAALFVGVGAISFGSIFVKLSETQLSPNATVFNRLWLASVFFLLWNGYKAIRQRLSSDKPVeeqcytsqdLWLLGSAGI 89
Cdd:COG0697     4 GILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDW---------LLLLLRGLL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  90 FWAGTLVFLAWSLTETSVAISSVLHNLAPIFTSLGVWLLYRKAFESQFLIGMVIALGGAIAIEFEELQIATDEVQGGFAA 169
Cdd:COG0697    75 GLALAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLGDLLA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 170 IVSAIFLSGYLLLVEKLRTKFTPTTIQLWICTISALVIFPILLFTqDPLFPSTVSGWLWVISLALICQVLGHGLLTYSLA 249
Cdd:COG0697   155 LLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLT-GLPLPLSAAAWLALLYLGLFGTALAYLLWFRALR 233

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1349665228 250 KFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYLAV 298
Cdd:COG0697   234 RLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 340-630 3.43e-33

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 128.81  E-value: 3.43e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 340 FLGTASLLFALIPISLAPSLTKLCQQEIGANAVVFHRSWIATIVFALWNGLEafgsqqsdnePIEKKPFTSQEVWLLLAM 419
Cdd:COG0697     2 LRGILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLR----------GRRLPPLSRRDWLLLLLR 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 420 GTSAGT-YLLLWAWSLSQTSVANVALLSNLNSLFVALAGYLLFGRRFDNRFVIGLVIALGGAIAFELNKVQFATAQILGD 498
Cdd:COG0697    72 GLLGLAlAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLGD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 499 ALALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLvAFLEDRLLPYSWMGWFFIIFQALFCQVLGQGLLAY 578
Cdd:COG0697   152 LLALLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPL-ALLTGLPLPLSAAAWLALLYLGLFGTALAYLLWFR 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1349665228 579 SLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYLAQ 630
Cdd:COG0697   231 ALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 10-298 3.31e-30

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 120.33  E-value: 3.31e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  10 ALAALFVGVGAISFGSIFVKLSETQLSPNATVFNRLWLASVFFLLWNGYKAIRQRLSSDKPVeeqcytsqdLWLLGSAGI 89
Cdd:COG0697     4 GILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDW---------LLLLLRGLL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  90 FWAGTLVFLAWSLTETSVAISSVLHNLAPIFTSLGVWLLYRKAFESQFLIGMVIALGGAIAIEFEELQIATDEVQGGFAA 169
Cdd:COG0697    75 GLALAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLGDLLA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 170 IVSAIFLSGYLLLVEKLRTKFTPTTIQLWICTISALVIFPILLFTqDPLFPSTVSGWLWVISLALICQVLGHGLLTYSLA 249
Cdd:COG0697   155 LLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLT-GLPLPLSAAAWLALLYLGLFGTALAYLLWFRALR 233

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1349665228 250 KFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYLAV 298
Cdd:COG0697   234 RLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 495-628 4.50e-13

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 66.45  E-value: 4.50e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 495 ILGDALALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLvAFLEDRLLPYSWMGWFFIIFQALFCQVLGQG 574
Cdd:pfam00892   1 LKGILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIAGILLLPF-ALFTGGKLVIPLKSWLALLYLGVLGTFLGFL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1349665228 575 LLAYSLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYL 628
Cdd:pfam00892  80 LYFYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLL 133
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 165-299 4.04e-11

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 61.06  E-value: 4.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 165 GGFAAIVSAIFLSGYLLLVEKLRTKFTPTTIQLWICTISALVIFPILLFTQDPLFPStVSGWLWVISLALICQVLGHGLL 244
Cdd:pfam00892   3 GILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIAGILLLPFALFTGGKLVIP-LKSWLALLYLGVLGTFLGFLLY 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1349665228 245 TYSLAKFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYLAVS 299
Cdd:pfam00892  82 FYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLILL 136
2A78 TIGR00950
Carboxylate/Amino Acid/Amine Transporter; [Transport and binding proteins, Amino acids, ...
 81-294 5.91e-11

Carboxylate/Amino Acid/Amine Transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273359 [Multi-domain]  Cd Length: 260  Bit Score: 63.48  E-value: 5.91e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  81 LWLLGSAGIFWAGTLVFLAwsLTETSVAISSVLHNLAPIFTSLGVWLLYRKAFESQFLIGMVIALGGAIAIEFeeLQIAT 160
Cdd:TIGR00950  49 LLLLGALQIGVFYVLYFVA--VKRLPVGEAALLLYLAPLYVTLLSDLMGKERPRKLVLLAAVLGLAGAVLLLS--DGNLS 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 161 DEVQGGFAAIVSAIFLSGYLLLVEKLRTKFTPTTIQL--WICTISALVIFPILLFtQDPLFPSTVSGWLWVISLALICQV 238
Cdd:TIGR00950 125 INPAGLLLGLGSGISFALGTVLYKRLVKKEGPELLQFtgWVLLLGALLLLPFAWF-LGPNPQALSLQWGALLYLGLIGTA 203

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1349665228 239 LGHGLLTYSLAKFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGL 294
Cdd:TIGR00950 204 LAYFLWNKGLTLVDPSAASILALAEPLVALLLGLLILGETLSLPQLIGGALIIAAV 259
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 340-630 3.43e-33

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 128.81  E-value: 3.43e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 340 FLGTASLLFALIPISLAPSLTKLCQQEIGANAVVFHRSWIATIVFALWNGLEafgsqqsdnePIEKKPFTSQEVWLLLAM 419
Cdd:COG0697     2 LRGILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLR----------GRRLPPLSRRDWLLLLLR 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 420 GTSAGT-YLLLWAWSLSQTSVANVALLSNLNSLFVALAGYLLFGRRFDNRFVIGLVIALGGAIAFELNKVQFATAQILGD 498
Cdd:COG0697    72 GLLGLAlAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLGD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 499 ALALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLvAFLEDRLLPYSWMGWFFIIFQALFCQVLGQGLLAY 578
Cdd:COG0697   152 LLALLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPL-ALLTGLPLPLSAAAWLALLYLGLFGTALAYLLWFR 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1349665228 579 SLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYLAQ 630
Cdd:COG0697   231 ALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 10-298 3.31e-30

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 120.33  E-value: 3.31e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  10 ALAALFVGVGAISFGSIFVKLSETQLSPNATVFNRLWLASVFFLLWNGYKAIRQRLSSDKPVeeqcytsqdLWLLGSAGI 89
Cdd:COG0697     4 GILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDW---------LLLLLRGLL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  90 FWAGTLVFLAWSLTETSVAISSVLHNLAPIFTSLGVWLLYRKAFESQFLIGMVIALGGAIAIEFEELQIATDEVQGGFAA 169
Cdd:COG0697    75 GLALAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLGDLLA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 170 IVSAIFLSGYLLLVEKLRTKFTPTTIQLWICTISALVIFPILLFTqDPLFPSTVSGWLWVISLALICQVLGHGLLTYSLA 249
Cdd:COG0697   155 LLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLT-GLPLPLSAAAWLALLYLGLFGTALAYLLWFRALR 233

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1349665228 250 KFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYLAV 298
Cdd:COG0697   234 RLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282
RhtA COG5006
Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];
1-300 3.90e-20

Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];


Pssm-ID: 444030 [Multi-domain]  Cd Length: 290  Bit Score: 91.04  E-value: 3.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228   1 MNVSNQKKIALAALFVGVGAISFGSIFVKLSETQLSPNATVFNRLWLASVFFLLWngykaIRQRLSSdkpveeqcYTSQD 80
Cdd:COG5006     1 MSASSSRLPGVLLVLLSALSVQLGAALAKLLFPGVGPLGVTALRLAFAALILLLI-----FRPWRRR--------LTRRD 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  81 LWLLGSAGIFWAGTLVFLAWSLTETSVAISSVLHNLAPIFTSLgvwLLYRKAFEsqfLIGMVIALGGAIAIEFEELQIAT 160
Cdd:COG5006    68 WLALLLYGVALAGMNLLFYLAIARIPLGIAVALEFLGPLAVAL---LGSRRRRD---LLWVALALAGVVLLLPVGLSGGS 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 161 DEVQGGFAAIVSAIFLSGYLLLVEKLRTKFTPTTIQLWICTISALVIFPILLFTQDPLFPStVSGWLWVISLALICQVLG 240
Cdd:COG5006   142 LDPVGVLFALGAAACWALYILLGRRVGARLPGLTGLALGMLVAALVLLPFGLPTAGPALLD-PPVLLLGLGVAVLSSVLP 220

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 241 HGLLTYSLAKFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYLAVSS 300
Cdd:COG5006   221 YSLEMVALRRLPARTFGILMSLEPAVAALAGWLVLGEVLTPLQWLGIALVVAASAGATLT 280
RhtA COG5006
Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];
335-635 8.99e-19

Threonine/homoserine efflux transporter RhtA [Amino acid transport and metabolism];


Pssm-ID: 444030 [Multi-domain]  Cd Length: 290  Bit Score: 87.18  E-value: 8.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 335 SETPAFLGTASLLFALIPISLAPSLTKLCQQEIGANAVVFHRSWIATIVFALWNgleafgsqqsdnEPiEKKPFTSQEVW 414
Cdd:COG5006     3 ASSSRLPGVLLVLLSALSVQLGAALAKLLFPGVGPLGVTALRLAFAALILLLIF------------RP-WRRRLTRRDWL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 415 LLLAMGTSAGTYLLLWAWSLSQTSVANVALLSNLNSLFVALAGYLlfgRRFDnrfVIGLVIALGGAIAFELNKVQFATAQ 494
Cdd:COG5006    70 ALLLYGVALAGMNLLFYLAIARIPLGIAVALEFLGPLAVALLGSR---RRRD---LLWVALALAGVVLLLPVGLSGGSLD 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 495 ILGDALALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLVAFLEDRLLPySWMGWFFIIFQALFCQVLGQG 574
Cdd:COG5006   144 PVGVLFALGAAACWALYILLGRRVGARLPGLTGLALGMLVAALVLLPFGLPTAGPALL-DPPVLLLGLGVAVLSSVLPYS 222

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1349665228 575 LLAYSLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYLAQSSQST 635
Cdd:COG5006   223 LEMVALRRLPARTFGILMSLEPAVAALAGWLVLGEVLTPLQWLGIALVVAASAGATLTARR 283
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 167-487 1.12e-14

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 74.88  E-value: 1.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 167 FAAIVSAIFLSGYLLLVEKLRTKFTPTTIQLWICTISALVIFPILLFTQDPLFPSTVSGWLWVISLALICQVLGHGLLTY 246
Cdd:COG0697     6 LLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGLLGLALAFLLFFL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 247 SLAKFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYLAVSSQPAVNFPFqesvttivntfvksmtsk 326
Cdd:COG0697    86 ALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGS------------------ 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 327 lsllkqqfsetpaFLGTASLLFALIPISLAPSLTKLCQQEIGANAVVFHRSWIATIVFALWNGLEAFGSqqsdnepiekk 406
Cdd:COG0697   148 -------------LLGDLLALLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTGLPL----------- 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 407 PFTSQEVWLLLAMGT-SAGTYLLLWAWSLSQTSVANVALLSNLNSLFVALAGYLLFGRRFDNRFVIGLVIALGGAIAFEL 485
Cdd:COG0697   204 PLSAAAWLALLYLGLfGTALAYLLWFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAAL 283


                  ..
gi 1349665228 486 NK 487
Cdd:COG0697   284 RE 285
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 495-628 4.50e-13

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 66.45  E-value: 4.50e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 495 ILGDALALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLvAFLEDRLLPYSWMGWFFIIFQALFCQVLGQG 574
Cdd:pfam00892   1 LKGILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIAGILLLPF-ALFTGGKLVIPLKSWLALLYLGVLGTFLGFL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1349665228 575 LLAYSLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYL 628
Cdd:pfam00892  80 LYFYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLL 133
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 494-628 1.52e-11

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 65.63  E-value: 1.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 494 QILGDALALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLVAFLEDRLLPYSWMGWFFIIFQALFCQVLGQ 573
Cdd:COG0697     1 RLRGILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGLLGLALAF 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1349665228 574 GLLAYSLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYL 628
Cdd:COG0697    81 LLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLL 135
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 165-299 4.04e-11

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 61.06  E-value: 4.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 165 GGFAAIVSAIFLSGYLLLVEKLRTKFTPTTIQLWICTISALVIFPILLFTQDPLFPStVSGWLWVISLALICQVLGHGLL 244
Cdd:pfam00892   3 GILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIAGILLLPFALFTGGKLVIP-LKSWLALLYLGVLGTFLGFLLY 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1349665228 245 TYSLAKFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYLAVS 299
Cdd:pfam00892  82 FYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLILL 136
2A78 TIGR00950
Carboxylate/Amino Acid/Amine Transporter; [Transport and binding proteins, Amino acids, ...
 81-294 5.91e-11

Carboxylate/Amino Acid/Amine Transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273359 [Multi-domain]  Cd Length: 260  Bit Score: 63.48  E-value: 5.91e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  81 LWLLGSAGIFWAGTLVFLAwsLTETSVAISSVLHNLAPIFTSLGVWLLYRKAFESQFLIGMVIALGGAIAIEFeeLQIAT 160
Cdd:TIGR00950  49 LLLLGALQIGVFYVLYFVA--VKRLPVGEAALLLYLAPLYVTLLSDLMGKERPRKLVLLAAVLGLAGAVLLLS--DGNLS 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 161 DEVQGGFAAIVSAIFLSGYLLLVEKLRTKFTPTTIQL--WICTISALVIFPILLFtQDPLFPSTVSGWLWVISLALICQV 238
Cdd:TIGR00950 125 INPAGLLLGLGSGISFALGTVLYKRLVKKEGPELLQFtgWVLLLGALLLLPFAWF-LGPNPQALSLQWGALLYLGLIGTA 203

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1349665228 239 LGHGLLTYSLAKFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGL 294
Cdd:TIGR00950 204 LAYFLWNKGLTLVDPSAASILALAEPLVALLLGLLILGETLSLPQLIGGALIIAAV 259
RibN COG2510
Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];
500-628 3.97e-05

Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];


Pssm-ID: 442000  Cd Length: 138  Bit Score: 43.63  E-value: 3.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 500 LALLTAVFMATCMLLIERLRTRFSTATIMLWRCGVTTMFLLPLVAFLED--RLLPYSWMGWFFIIFQALFcQVLGQGLLA 577
Cdd:COG2510     5 LALLSAFFAGLTAIFAKIGLKGIDPNLATFIRTLVALIFLLLILLVTGKlgELPELSPKSWLFLLLSGLA-TGLSWLFYF 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1349665228 578 YSLSRISSSVVAVTLLLEPVLASIFAWFIFSEQVGLFDWATFAVVLVGIYL 628
Cdd:COG2510    84 RALKLGPASIVAPIDKLSPVFTVLLSVLFLGERLTLKQIIGILLIVAGVIL 134
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 11-151 7.66e-04

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 40.26  E-value: 7.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228  11 LAALFVGVGAISFGSIFV--KLSETQLSPNATVFNRLWLASVFFLLWNGYKAIRQRLSsdkpveeqcyTSQDLWLLGSAG 88
Cdd:pfam00892   2 KGILLALLAALIWAIYFVfsKILLRRISPLTLTFWRFLIAGILLLPFALFTGGKLVIP----------LKSWLALLYLGV 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1349665228  89 IFWAGTLVFLAWSLTETSVAISSVLHNLAPIFTSLGVWLLYRKAFESQFLIGMVIALGGAIAI 151
Cdd:pfam00892  72 LGTFLGFLLYFYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLI 134
RibN COG2510
Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];
167-296 1.00e-03

Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];


Pssm-ID: 442000  Cd Length: 138  Bit Score: 39.78  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 167 FAAIVSAIFLSGYLLLvEKLRTKFTPTTIQLWICTISALVIFPILLFTQDPLFPSTVSGWLWVISLAL--ICQVLGHGLL 244
Cdd:COG2510     4 LLALLSAFFAGLTAIF-AKIGLKGIDPNLATFIRTLVALIFLLLILLVTGKLGELPELSPKSWLFLLLsgLATGLSWLFY 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1349665228 245 TYSLAKFSSVVVSLVHLLEPVFSGIFAPIVFSEKLTFSNWAGFAVVLMGLYL 296
Cdd:COG2510    83 FRALKLGPASIVAPIDKLSPVFTVLLSVLFLGERLTLKQIIGILLIVAGVIL 134
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 354-481 1.07e-03

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 39.49  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1349665228 354 SLAPSLTKLCQQEIGANAVVFHRSWIATIVFALWNGLEafgsqqsdnepIEKKPFTSQEVWLLLAMGTSAGT-YLLLWAW 432
Cdd:pfam00892  15 AIYFVFSKILLRRISPLTLTFWRFLIAGILLLPFALFT-----------GGKLVIPLKSWLALLYLGVLGTFlGFLLYFY 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1349665228 433 SLSQTSVANVALLSNLNSLFVALAGYLLFGRRFDNRFVIGLVIALGGAI 481
Cdd:pfam00892  84 GLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVL 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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