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MULTISPECIES: Na+/H+ antiporter NhaA [unclassified Rathayibacter]
Protein Classification
Na+/H+ antiporter NhaA ( domain architecture ID 10006841 )
Na+/H+ antiporter NhaA extrudes sodium in exchange for external protons
List of domain hits
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
19-417
1.54e-132
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 385.98
E-value: 1.54e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 19 LR QT L QKDTV GG AF LL T A TL LALI V ANSP ASAL Y S A VRDFRF G PE -- A LHL E LS VGS W AA DGL L AIFFF V VGLE L K E E FV 96
Cdd:COG3004 1 LR RF L RSEAA GG IL LL L A AV LALI W ANSP LAES Y E A LLHTPL G LG ig S LHL D LS LLH W IN DGL M AIFFF L VGLE I K R E LL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 97 A G K L RD P KT A LV PI V AA V GG VA VPALI FT A V N LP r GGA A LD GWAIP A ATDIAFA VA V I A VV G RFL P PA LR T FLL T LA V VD 176
Cdd:COG3004 81 V G E L SS P RK A AL PI I AA L GG MV VPALI YL A F N AG - TPE A AR GWAIP M ATDIAFA LG V L A LL G SRV P AS LR V FLL A LA I VD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 177 DL I AI TI IA V FYT A G IDV L M LLLA LVP LA VF A VCVQ RGVR AW W VLIP LGV AT W AL V HA SG I HAT V AGVLL GF T V P VVATK 256
Cdd:COG3004 160 DL G AI LV IA L FYT S G LSL L A LLLA AAA LA LL A LLNR RGVR SL W PYLL LGV VL W YA V LK SG V HAT L AGVLL AL T I P ARPRV 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 257 RARVQVG S daegrpvydg LAAHFADRWSVLSTAVAV P V FAF FS AGV TVG G VAG lv DSFQDSIAV GI IA GLVLGKPLGI A G 336
Cdd:COG3004 240 GGEEEAE S ---------- PLERLEHALHPWVAFLIL P L FAF AN AGV SLS G LSL -- AALTSPVTL GI AL GLVLGKPLGI F G 307
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 337 STF L LTRFRGIG L DPSLR W VDVI G MAFV AGIGFT V SL LVG EL S F G a GS E SD D HV K V G V L A GS F LAAV I G GAI L SV R N R HY 416
Cdd:COG3004 308 FSW L AVKLGLAR L PAGVS W RQLY G VGLL AGIGFT M SL FIA EL A F P - DP E LL D AA K L G I L L GS L LAAV L G YLL L RL R L R RK 386
.
gi 1345817988 417 R 417
Cdd:COG3004 387 R 387
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
19-417
1.54e-132
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 385.98
E-value: 1.54e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 19 LR QT L QKDTV GG AF LL T A TL LALI V ANSP ASAL Y S A VRDFRF G PE -- A LHL E LS VGS W AA DGL L AIFFF V VGLE L K E E FV 96
Cdd:COG3004 1 LR RF L RSEAA GG IL LL L A AV LALI W ANSP LAES Y E A LLHTPL G LG ig S LHL D LS LLH W IN DGL M AIFFF L VGLE I K R E LL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 97 A G K L RD P KT A LV PI V AA V GG VA VPALI FT A V N LP r GGA A LD GWAIP A ATDIAFA VA V I A VV G RFL P PA LR T FLL T LA V VD 176
Cdd:COG3004 81 V G E L SS P RK A AL PI I AA L GG MV VPALI YL A F N AG - TPE A AR GWAIP M ATDIAFA LG V L A LL G SRV P AS LR V FLL A LA I VD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 177 DL I AI TI IA V FYT A G IDV L M LLLA LVP LA VF A VCVQ RGVR AW W VLIP LGV AT W AL V HA SG I HAT V AGVLL GF T V P VVATK 256
Cdd:COG3004 160 DL G AI LV IA L FYT S G LSL L A LLLA AAA LA LL A LLNR RGVR SL W PYLL LGV VL W YA V LK SG V HAT L AGVLL AL T I P ARPRV 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 257 RARVQVG S daegrpvydg LAAHFADRWSVLSTAVAV P V FAF FS AGV TVG G VAG lv DSFQDSIAV GI IA GLVLGKPLGI A G 336
Cdd:COG3004 240 GGEEEAE S ---------- PLERLEHALHPWVAFLIL P L FAF AN AGV SLS G LSL -- AALTSPVTL GI AL GLVLGKPLGI F G 307
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 337 STF L LTRFRGIG L DPSLR W VDVI G MAFV AGIGFT V SL LVG EL S F G a GS E SD D HV K V G V L A GS F LAAV I G GAI L SV R N R HY 416
Cdd:COG3004 308 FSW L AVKLGLAR L PAGVS W RQLY G VGLL AGIGFT M SL FIA EL A F P - DP E LL D AA K L G I L L GS L LAAV L G YLL L RL R L R RK 386
.
gi 1345817988 417 R 417
Cdd:COG3004 387 R 387
Na_H_antiport_1
pfam06965 Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. ...
20-408
1.03e-128
Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.
Pssm-ID: 429217
Cd Length: 378
Bit Score: 375.97
E-value: 1.03e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 20 R QT L QKDTV GG AF LL T A TL LALI V ANSP ASAL Y S A VRDFRF G PEALH L E -- LS VGS W AA DGL L AIFFFVVGLE L K E E FVA 97
Cdd:pfam06965 1 R RF L RSEAA GG IL LL A A AV LALI W ANSP LADS Y E A LWHTPL G VGFGG L S ls LS LHH W IN DGL M AIFFFVVGLE I K R E LLV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 98 G K L RD P KT A LV P IV AA V GG VA VPALI FT A V N L pr GG AALD GWAIP A ATDIAFA VA V I A VV G RFL P PA LR T FLL T LA V VDD 177
Cdd:pfam06965 81 G E L SS P RK A AL P VI AA L GG MV VPALI YL A F N A -- GG PGAR GWAIP M ATDIAFA LG V L A LL G KRV P AS LR V FLL A LA I VDD 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 178 L I AI TI IA V FYT A G IDV L M LL L A LVP LAV FAVCVQR GVR AW W VLIP LGV AT W AL V HA SG I HAT V AGVLL GFTV P VVATK R 257
Cdd:pfam06965 159 L G AI LV IA L FYT S G LSL L A LL A A AAI LAV LLLLNRL GVR RL W PYLL LGV VL W VA V LK SG V HAT I AGVLL ALLI P ARPPA R 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 258 ARVQVG S DA E grpvydglaa HFADRWSVLSTAVAV P V FA FFS AGV TVG G V a GL VDSFQDSIAV GI IA GLVLGKPLGI A G S 337
Cdd:pfam06965 239 ESREAI S PL E ---------- RLEHALHPWVAFLIL P L FA LAN AGV SLS G S - GL GALLTSPVTL GI AL GLVLGKPLGI F G F 307
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1345817988 338 TF L LTRFRGIG L DPSLR W VDVI G MAFV AGIGFT V SL LVG EL S F GAGS E SD D HV K V G V L A GS F LAAV I G GAI 408
Cdd:pfam06965 308 SW L AVKLGLAR L PEGVT W RQLL G VGLL AGIGFT M SL FIA EL A F DDEL E LL D EA K L G I L L GS L LAAV L G YLV 378
nhaA
PRK09560 pH-dependent sodium/proton antiporter; Reviewed
19-415
2.65e-81
pH-dependent sodium/proton antiporter; Reviewed
Pssm-ID: 236568
Cd Length: 389
Bit Score: 255.20
E-value: 2.65e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 19 L R QT L QKDTV GG AF L LT A TL LA L IVANSP A S AL Y SAVRD -- FRFGPE A LHLEL S VGS W AA DGL L A I FF FV VGLE L K E E FV 96
Cdd:PRK09560 5 I R RF L KSEAA GG IL L MA A AA LA M IVANSP L S EG Y FSFLH tp VAIQIG A FSIGK S LLH W IN DGL M A V FF LL VGLE I K R E LL 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 97 A G K L RDPKTALV P IV AAVGG VA VPALI FT A V N L p RGGAA L D GWAIPAATDIAFA VA V I A VV G RFL P PA L RT FLL T LA VV D 176
Cdd:PRK09560 85 E G Q L SSWQQRIL P AI AAVGG MV VPALI YA A F N Y - NNPET L R GWAIPAATDIAFA LG V L A LL G KRV P VS L KV FLL A LA II D 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 177 DL I AI T IIA V FYT AGIDVLM L L LA LVPL AV FAVCVQR GV RAWWVLIPL G VAT W AL V HA SG I HAT V AGV L L G F TV P VVAT K 256
Cdd:PRK09560 164 DL G AI V IIA L FYT SDLSLPA L A LA AIAI AV LFLLNRL GV TKLTPYLIV G AIL W FA V LK SG V HAT L AGV V L A F CI P LKGK K 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 257 rarvqvgs DA E GR P VYD gl AA H FADR W SVL sta VAV P V FAF FS AGV TVG G VA gl VD S FQDSIAV GI IA GL V LGK PL G IA G 336
Cdd:PRK09560 244 -------- GD E ES P LHH -- LE H ALHP W VAF --- AIL P L FAF AN AGV SLA G IS -- LS S LTSPVPL GI AL GL F LGK QV G VF G 308
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1345817988 337 STF L LTRFRGIG L DPSLR W VDVI G MAFVA GIGFT V SL LV G E L S FGA GS E SDDHVKV G V L A GS F L A A VI G GAI L SVRN R H 415
Cdd:PRK09560 309 FSW L AVKLGLAK L PEGAN W KQIY G VSVLC GIGFT M SL FI G S L A FGA SE E LLTEARL G I L L GS L L S A IL G YLL L RLTL R K 387
NhaA
TIGR00773 Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family ...
26-409
3.46e-65
Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273264
Cd Length: 373
Bit Score: 213.10
E-value: 3.46e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 26 DTV GG AF L LT A TL LA LIV ANS PA S AL Y SAVRDFRFGPEALHLEL -- S VGS W AA DGL L A I FF FVV GLE L K E E FVA G K L RDP 103
Cdd:TIGR00773 5 ESA GG IL L VI A AA LA MVM ANS AL S EW Y HDFLHTPVQLQIGSFVI gk S LLH W IN DGL M A V FF LLI GLE V K R E LLE G A L SSL 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 104 KT A LV P IV AA V GG VAV PALI FT A V N L p RGGAALD GWAIPAATDIAFA VA V I A VV G RFL P P AL RT FLL T LA VV DDL I AI T I 183
Cdd:TIGR00773 85 RQ A IF P VI AA I GG MIA PALI YL A F N A - NDPITRE GWAIPAATDIAFA LG V M A LL G KRV P L AL KI FLL A LA II DDL G AI V I 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 184 IA V FYT AGIDVLM LL L A L V PL AV F AV CVQR GVR AWWVLIPL GV AT W AL V HA SG I HAT V AGV LL GF TV P VVAT K rarvqvg 263
Cdd:TIGR00773 164 IA L FYT NDLSMAA LL V A A V AI AV L AV LNRC GVR RLGPYMLV GV IL W FA V LK SG V HAT L AGV II GF FI P LKGK K ------- 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 264 sdae G RPVYDG L a A H FADR W SVL sta VAV P V FAF FS AGV TVG GV A gl VDSFQDSIAV GII A GL VL GKPLGI AGSTFLLTR 343
Cdd:TIGR00773 237 ---- G ESPLKR L - E H VLHP W VAY --- LIL P L FAF AN AGV SLQ GV S -- LNGLTSMLPL GII L GL LI GKPLGI FLFSWIAVK 306
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1345817988 344 FRGIG L DPSLRWVDVIGMAFVA GIGFT V S LLVGE L S FG - AGS E SDDHV K V G V L A GS FLA AV I G GAI L 409
Cdd:TIGR00773 307 LKLAK L PEGINFKQIFAVGVLC GIGFT M S IFIAS L A FG s VDP E LITWA K L G I L L GS TTS AV L G YSW L 373
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
19-417
1.54e-132
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 385.98
E-value: 1.54e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 19 LR QT L QKDTV GG AF LL T A TL LALI V ANSP ASAL Y S A VRDFRF G PE -- A LHL E LS VGS W AA DGL L AIFFF V VGLE L K E E FV 96
Cdd:COG3004 1 LR RF L RSEAA GG IL LL L A AV LALI W ANSP LAES Y E A LLHTPL G LG ig S LHL D LS LLH W IN DGL M AIFFF L VGLE I K R E LL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 97 A G K L RD P KT A LV PI V AA V GG VA VPALI FT A V N LP r GGA A LD GWAIP A ATDIAFA VA V I A VV G RFL P PA LR T FLL T LA V VD 176
Cdd:COG3004 81 V G E L SS P RK A AL PI I AA L GG MV VPALI YL A F N AG - TPE A AR GWAIP M ATDIAFA LG V L A LL G SRV P AS LR V FLL A LA I VD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 177 DL I AI TI IA V FYT A G IDV L M LLLA LVP LA VF A VCVQ RGVR AW W VLIP LGV AT W AL V HA SG I HAT V AGVLL GF T V P VVATK 256
Cdd:COG3004 160 DL G AI LV IA L FYT S G LSL L A LLLA AAA LA LL A LLNR RGVR SL W PYLL LGV VL W YA V LK SG V HAT L AGVLL AL T I P ARPRV 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 257 RARVQVG S daegrpvydg LAAHFADRWSVLSTAVAV P V FAF FS AGV TVG G VAG lv DSFQDSIAV GI IA GLVLGKPLGI A G 336
Cdd:COG3004 240 GGEEEAE S ---------- PLERLEHALHPWVAFLIL P L FAF AN AGV SLS G LSL -- AALTSPVTL GI AL GLVLGKPLGI F G 307
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 337 STF L LTRFRGIG L DPSLR W VDVI G MAFV AGIGFT V SL LVG EL S F G a GS E SD D HV K V G V L A GS F LAAV I G GAI L SV R N R HY 416
Cdd:COG3004 308 FSW L AVKLGLAR L PAGVS W RQLY G VGLL AGIGFT M SL FIA EL A F P - DP E LL D AA K L G I L L GS L LAAV L G YLL L RL R L R RK 386
.
gi 1345817988 417 R 417
Cdd:COG3004 387 R 387
Na_H_antiport_1
pfam06965 Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. ...
20-408
1.03e-128
Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.
Pssm-ID: 429217
Cd Length: 378
Bit Score: 375.97
E-value: 1.03e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 20 R QT L QKDTV GG AF LL T A TL LALI V ANSP ASAL Y S A VRDFRF G PEALH L E -- LS VGS W AA DGL L AIFFFVVGLE L K E E FVA 97
Cdd:pfam06965 1 R RF L RSEAA GG IL LL A A AV LALI W ANSP LADS Y E A LWHTPL G VGFGG L S ls LS LHH W IN DGL M AIFFFVVGLE I K R E LLV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 98 G K L RD P KT A LV P IV AA V GG VA VPALI FT A V N L pr GG AALD GWAIP A ATDIAFA VA V I A VV G RFL P PA LR T FLL T LA V VDD 177
Cdd:pfam06965 81 G E L SS P RK A AL P VI AA L GG MV VPALI YL A F N A -- GG PGAR GWAIP M ATDIAFA LG V L A LL G KRV P AS LR V FLL A LA I VDD 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 178 L I AI TI IA V FYT A G IDV L M LL L A LVP LAV FAVCVQR GVR AW W VLIP LGV AT W AL V HA SG I HAT V AGVLL GFTV P VVATK R 257
Cdd:pfam06965 159 L G AI LV IA L FYT S G LSL L A LL A A AAI LAV LLLLNRL GVR RL W PYLL LGV VL W VA V LK SG V HAT I AGVLL ALLI P ARPPA R 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 258 ARVQVG S DA E grpvydglaa HFADRWSVLSTAVAV P V FA FFS AGV TVG G V a GL VDSFQDSIAV GI IA GLVLGKPLGI A G S 337
Cdd:pfam06965 239 ESREAI S PL E ---------- RLEHALHPWVAFLIL P L FA LAN AGV SLS G S - GL GALLTSPVTL GI AL GLVLGKPLGI F G F 307
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1345817988 338 TF L LTRFRGIG L DPSLR W VDVI G MAFV AGIGFT V SL LVG EL S F GAGS E SD D HV K V G V L A GS F LAAV I G GAI 408
Cdd:pfam06965 308 SW L AVKLGLAR L PEGVT W RQLL G VGLL AGIGFT M SL FIA EL A F DDEL E LL D EA K L G I L L GS L LAAV L G YLV 378
nhaA
PRK09560 pH-dependent sodium/proton antiporter; Reviewed
19-415
2.65e-81
pH-dependent sodium/proton antiporter; Reviewed
Pssm-ID: 236568
Cd Length: 389
Bit Score: 255.20
E-value: 2.65e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 19 L R QT L QKDTV GG AF L LT A TL LA L IVANSP A S AL Y SAVRD -- FRFGPE A LHLEL S VGS W AA DGL L A I FF FV VGLE L K E E FV 96
Cdd:PRK09560 5 I R RF L KSEAA GG IL L MA A AA LA M IVANSP L S EG Y FSFLH tp VAIQIG A FSIGK S LLH W IN DGL M A V FF LL VGLE I K R E LL 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 97 A G K L RDPKTALV P IV AAVGG VA VPALI FT A V N L p RGGAA L D GWAIPAATDIAFA VA V I A VV G RFL P PA L RT FLL T LA VV D 176
Cdd:PRK09560 85 E G Q L SSWQQRIL P AI AAVGG MV VPALI YA A F N Y - NNPET L R GWAIPAATDIAFA LG V L A LL G KRV P VS L KV FLL A LA II D 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 177 DL I AI T IIA V FYT AGIDVLM L L LA LVPL AV FAVCVQR GV RAWWVLIPL G VAT W AL V HA SG I HAT V AGV L L G F TV P VVAT K 256
Cdd:PRK09560 164 DL G AI V IIA L FYT SDLSLPA L A LA AIAI AV LFLLNRL GV TKLTPYLIV G AIL W FA V LK SG V HAT L AGV V L A F CI P LKGK K 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 257 rarvqvgs DA E GR P VYD gl AA H FADR W SVL sta VAV P V FAF FS AGV TVG G VA gl VD S FQDSIAV GI IA GL V LGK PL G IA G 336
Cdd:PRK09560 244 -------- GD E ES P LHH -- LE H ALHP W VAF --- AIL P L FAF AN AGV SLA G IS -- LS S LTSPVPL GI AL GL F LGK QV G VF G 308
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1345817988 337 STF L LTRFRGIG L DPSLR W VDVI G MAFVA GIGFT V SL LV G E L S FGA GS E SDDHVKV G V L A GS F L A A VI G GAI L SVRN R H 415
Cdd:PRK09560 309 FSW L AVKLGLAK L PEGAN W KQIY G VSVLC GIGFT M SL FI G S L A FGA SE E LLTEARL G I L L GS L L S A IL G YLL L RLTL R K 387
nhaA
PRK09561 sodium/proton antiporter NhaA;
17-412
6.62e-69
sodium/proton antiporter NhaA;
Pssm-ID: 181955
Cd Length: 388
Bit Score: 223.22
E-value: 6.62e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 17 RGL R QT L QKDTV GG AF L LT A TL LA LIV ANSP A S AL Y SAVRD ---- F R F G pe AL HLELSVGS W AA DGL L A I FF FVV GLE L K 92
Cdd:PRK09561 3 KHI R RF L SSEAS GG IL L II A AA LA MLM ANSP T S GW Y QDFLE tpvq L R V G -- AL EINKPLLL W IN DGL M A V FF LLI GLE V K 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 93 E E FVA G K L RDPKT A LV P IV AA V GG VA VPALI FTAV N L p RGGAALD GWAIPAATDIAFA VA V I A VV G RFL P P AL RT FLL T L 172
Cdd:PRK09561 81 R E LLE G S L ASRRQ A AL P VI AA I GG ML VPALI YLLF N Y - ADPVTRE GWAIPAATDIAFA LG V L A LL G SRV P V AL KI FLL A L 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 173 A VV DDL I AI T IIA V FYT AGIDVLM L LL A L V PL AV F AV CVQR GVR AWW V L I PL GV AT W AL V HA SG I HAT V AGV LL GF TV P V 252
Cdd:PRK09561 160 A II DDL G AI V IIA L FYT SDLSMVS L GV A A V AI AV L AV LNLC GVR RTS V Y I LV GV VL W VA V LK SG V HAT L AGV IV GF FI P L 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 253 vatkra RVQV G S d AEGRPVYD GL aa H FADRWSV L stavav P V FAF FS AGV TVG GV A gl V D SFQDSIAV GI IA GL VL GKPL 332
Cdd:PRK09561 240 ------ KEKH G R - SPAERLEH GL -- H PWVAFLI L ------ P L FAF AN AGV SLQ GV T -- L D GLTSPLPL GI AL GL FI GKPL 302
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 333 GI AGSTF L LTRFRGIG L DPSLRWVDVIGMAFVA GIGFT V S LLVGE L S F - G AGS E SDDHV K V G V L A GS F L A AVIG GAI L SV 411
Cdd:PRK09561 303 GI FLFSW L AVKLKLAK L PEGTTFKQIYAVGVLC GIGFT M S IFIAS L A F g G VDP E LINYA K L G I L I GS L L S AVIG YSW L RK 382
.
gi 1345817988 412 R 412
Cdd:PRK09561 383 V 383
NhaA
TIGR00773 Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family ...
26-409
3.46e-65
Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273264
Cd Length: 373
Bit Score: 213.10
E-value: 3.46e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 26 DTV GG AF L LT A TL LA LIV ANS PA S AL Y SAVRDFRFGPEALHLEL -- S VGS W AA DGL L A I FF FVV GLE L K E E FVA G K L RDP 103
Cdd:TIGR00773 5 ESA GG IL L VI A AA LA MVM ANS AL S EW Y HDFLHTPVQLQIGSFVI gk S LLH W IN DGL M A V FF LLI GLE V K R E LLE G A L SSL 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 104 KT A LV P IV AA V GG VAV PALI FT A V N L p RGGAALD GWAIPAATDIAFA VA V I A VV G RFL P P AL RT FLL T LA VV DDL I AI T I 183
Cdd:TIGR00773 85 RQ A IF P VI AA I GG MIA PALI YL A F N A - NDPITRE GWAIPAATDIAFA LG V M A LL G KRV P L AL KI FLL A LA II DDL G AI V I 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 184 IA V FYT AGIDVLM LL L A L V PL AV F AV CVQR GVR AWWVLIPL GV AT W AL V HA SG I HAT V AGV LL GF TV P VVAT K rarvqvg 263
Cdd:TIGR00773 164 IA L FYT NDLSMAA LL V A A V AI AV L AV LNRC GVR RLGPYMLV GV IL W FA V LK SG V HAT L AGV II GF FI P LKGK K ------- 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 264 sdae G RPVYDG L a A H FADR W SVL sta VAV P V FAF FS AGV TVG GV A gl VDSFQDSIAV GII A GL VL GKPLGI AGSTFLLTR 343
Cdd:TIGR00773 237 ---- G ESPLKR L - E H VLHP W VAY --- LIL P L FAF AN AGV SLQ GV S -- LNGLTSMLPL GII L GL LI GKPLGI FLFSWIAVK 306
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1345817988 344 FRGIG L DPSLRWVDVIGMAFVA GIGFT V S LLVGE L S FG - AGS E SDDHV K V G V L A GS FLA AV I G GAI L 409
Cdd:TIGR00773 307 LKLAK L PEGINFKQIFAVGVLC GIGFT M S IFIAS L A FG s VDP E LITWA K L G I L L GS TTS AV L G YSW L 373
nhaA
PRK14856 sodium/proton antiporter NhaA;
15-414
8.44e-62
sodium/proton antiporter NhaA;
Pssm-ID: 184858
Cd Length: 438
Bit Score: 206.19
E-value: 8.44e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 15 IWRG L RQTLQKDTV GG A FL LTATL LA LI VANS PASAL Y S A V -- RD F R F GPEALHLEL S VGS W AA D G L L A I FF FVV GLE L K 92
Cdd:PRK14856 10 LSLT L KNFIKSESF GG I FL FLNAV LA MV VANS FLKES Y F A L wh TP F G F QIGDFFIGF S LHN W ID D V L M A L FF LMI GLE I K 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 93 E E FVA G K L RDP K T A LV P IV AA V GG VAV P A LI FTAV N L pr GGAALD G WA IP A ATDIAFA VA VI AVV G RFL P P AL RT FL L TL 172
Cdd:PRK14856 90 R E LLF G E L SSF K K A SF P VI AA L GG MIA P G LI YFFL N A -- DTPSQH G FG IP M ATDIAFA LG VI MLL G KRV P T AL KV FL I TL 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 173 AV V DDL I AI TI IA V FYT AGIDVLM LL L AL VPLA V F AV CVQRG VR AWWVLIP LGV AT W AL VH A SGIHAT V A G V L L G F TV PV 252
Cdd:PRK14856 168 AV A DDL G AI VV IA L FYT TNLKFAW LL G AL GVVL V L AV LNRLN VR SLIPYLL LGV LL W FC VH Q SGIHAT I A A V V L A F MI PV 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 253 VAT K RA --------------- RVQVGSDA E GRPVYDGLAAHFADRW S V L ---------- S TAVAV P V FAF FS AGV T vgg V 307
Cdd:PRK14856 248 KIP K DS knvellelgkryaet SSGALLTK E QQEILHSIEEKASALQ S P L erlehflapi S GYFIM P L FAF AN AGV S --- V 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 308 AGLVDSFQ D SIAV G I I A GL V LGKPLGI AGS TF LLTRF r G I GLD P S - LR W VDVI G MAFV AGIGFT V S LLVGE L S F GAGS - E 385
Cdd:PRK14856 325 DSSINLEV D KVLL G V I L GL C LGKPLGI FLI TF ISEKL - K I TAR P K g IS W WHIL G AGLL AGIGFT M S MFISN L A F TSEH k D 403
410 420
....*....|....*....|....*....
gi 1345817988 386 SDDHV K VGV L A GS FLAAV IG GAI L SVRNR 414
Cdd:PRK14856 404 AMEVA K IAI L L GS LISGI IG ALY L FALDK 432
nhaA
PRK14855 pH-dependent sodium/proton antiporter; Provisional
42-414
1.27e-60
pH-dependent sodium/proton antiporter; Provisional
Pssm-ID: 237836
Cd Length: 423
Bit Score: 202.41
E-value: 1.27e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 42 I V ANSP ASAL Y SAVRDFRFGPEA -- LH L E LS VGS W AA DGL L A I FF FV VGLE L K E E FVA G K L RD P KT A LVPI VAA V GG VA V 119
Cdd:PRK14855 32 I W ANSP WREG Y FTLQHTHLALSL gg WS L D LS LEH W VN DGL M A V FF LL VGLE I K R E LLI G E L SS P RQ A ALAV VAA L GG ML V 111
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 120 PA LIF TA V N L pr GG AALD GW AI P A ATDIAFA VA V I A VV G RFL P PA L RT FL LT LA V VDDL I A ITI IA V FYT A G IDV L M LLL 199
Cdd:PRK14855 112 PA ALY TA L N A -- GG PGAS GW GV P M ATDIAFA LG V L A LL G SRV P LG L KV FL TA LA I VDDL G A VLV IA L FYT S G LNL L A LLL 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 200 A LVPL A VFAVCVQR GV RAWWVLIP LG VAT W AL V HA SG I H A TVAGVLL GFT VP V --- VATKRARVQVGSD A E GRP VYD G LA 276
Cdd:PRK14855 190 A ALTW A LALLAGRL GV TSLKIYAV LG ALL W FF V LK SG L H P TVAGVLL ALA VP I rrr DPLPYLASLLDAA A P GRP EVV G AR 269
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 277 AHFADRWSV --------------- L ST AVAV PVFA F F S AGV T V G G v A GL vdsfq DSIAV G IIA GL V LGKPLG IA G STF L L 341
Cdd:PRK14855 270 LRDLEDLLE raqsplhrlehalhp W ST FLIL PVFA L F N AGV S V S G - G GL ----- GTVSL G VFL GL L LGKPLG VV G GAW L A 343
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1345817988 342 T R FRGIG L DPSLR W VDVI G MAFV AGIGFT V SL LVGE L S F GAGSES d DHV K V GVLA G S F LAA VI G GAI L SVRN R 414
Cdd:PRK14855 344 V R LGLAS L PRRVN W LHML G AGLL AGIGFT M SL FISN L A F ADAALL - TQA K L GVLA A S V LAA LL G AGW L WWAV R 415
nhaA
PRK14854 pH-dependent sodium/proton antiporter; Provisional
26-415
6.97e-49
pH-dependent sodium/proton antiporter; Provisional
Pssm-ID: 184856
Cd Length: 383
Bit Score: 170.41
E-value: 6.97e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 26 DTV GG AF L LT A T LLA LI V A NSP ASAL Y SAVR -- DFRF G P E A L HLELSVGS W AA DGL L AI F F FVV GLE L K E E FVA G K L RD P 103
Cdd:PRK14854 9 ELI GG LI L FS A A LLA IV V N NSP LASY Y AMLE ti NVKL G I E N L VIDKNLMH W IN DGL M AI Y F LYI GLE I K R E IIV G T L SK P 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 104 KTALV P IV AA VG G V A V P A LI FTAV N lp RGGAALD GWAIP A ATDIAF AVAVI A VV G RFL P PA L RTFLL T L A VV DD LI AI T I 183
Cdd:PRK14854 89 SNIIT P AI AA FA G L A M P S LI YLSI N -- HDIKVIN GWAIP S ATDIAF TLGIL A LL G TRV P AK L KLLVI T I A IF DD IA AI A I 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 184 IA V FYT AGIDV L M L L L ALVPLAVFAV C VQR - GVRAWW V LIP LG VAT W ALVHA SG I HAT V AG VLLGFTV P VVAT krarvqv 262
Cdd:PRK14854 167 IA I FYT KSLSL L S L S L GTLFILAMII C NRI f KINRSS V YVV LG FFA W FCTIK SG V HAT L AG FTTALCI P FREN ------- 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1345817988 263 GS D AEGRPVY D G L aahfa DR W SVL sta VAV PVFAF FS AG VTVG G VA gl VDSFQDS I AV GII A GL VL GK P LGI AGSTFLLT 342
Cdd:PRK14854 240 DK D SPANFME D S L ----- HP W IIY --- FIL PVFAF AN AG ISFS G IS -- FSILFEP I TL GII L GL FV GK Q LGI FSILAVFK 309
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1345817988 343 RFRGIG L DP S LRWVDVI G MAFVA GIGFT V SL LV G E L S F gagse S D D H ---- V K V GV LA GS F L AAVI G GAI L -- S V R N RH 415
Cdd:PRK14854 310 KLKWFK L GE S FSNLQLY G ISLLC GIGFT M SL FI G V L A F ----- N D T H llna I K I GV VV GS V L SGFF G YIV L rf I V T N PS 383
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
