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Conserved domains on  [gi|1339542544|gb|AUZ17088|]
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tandem affinity purification tag protein, partial [Cloning vector pCA-DEST1103]

Protein Classification

immunoglobulin G-binding protein A( domain architecture ID 10491241)

immunoglobulin G-binding protein A is a cell-wall-bound pathogenicity factor that avidly binds the Fc region of immunoglobulins from most mammalian species in a non-specific aggregation reaction that can lead to host tissue damage

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 59-109 3.20e-18

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


:

Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 74.12  E-value: 3.20e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1339542544  59 KFNKEQQNAFYEILHLPNLSEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 109
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 117-167 7.01e-18

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


:

Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 73.35  E-value: 7.01e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1339542544 117 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNGA 167
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
 
Name Accession Description Interval E-value
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 59-109 3.20e-18

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 74.12  E-value: 3.20e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1339542544  59 KFNKEQQNAFYEILHLPNLSEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 109
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 117-167 7.01e-18

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 73.35  E-value: 7.01e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1339542544 117 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNGA 167
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
 
Name Accession Description Interval E-value
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 59-109 3.20e-18

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 74.12  E-value: 3.20e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1339542544  59 KFNKEQQNAFYEILHLPNLSEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 109
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 117-167 7.01e-18

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 73.35  E-value: 7.01e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1339542544 117 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNGA 167
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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