NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1333114720|ref|XP_023531542|]
View 

transcription factor MYB101-like isoform X1 [Cucurbita pepo subsp. pepo]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 999994)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PLN03091 super family cl33633
hypothetical protein; Provisional
 26-131 3.98e-45

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PLN03091:

Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 164.38  E-value: 3.98e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333114720  26 LKKGPWTTAEDGILIEYVQKHGEGNWNAVQKHTGLARCGKSCRLRWANHLRPNLKKGSFSQEEERLIIELHAKLGNKWAR 105
Cdd:PLN03091   12 LRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQ 91

                          90       100
                  ....*....|....*....|....*...
gi 1333114720 106 MAAQLPGRTDNEIKNYWNTRMKR--RQR 131
Cdd:PLN03091   92 IAAQLPGRTDNEIKNLWNSCLKKklRQR 119
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 26-131 3.98e-45

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 164.38  E-value: 3.98e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333114720  26 LKKGPWTTAEDGILIEYVQKHGEGNWNAVQKHTGLARCGKSCRLRWANHLRPNLKKGSFSQEEERLIIELHAKLGNKWAR 105
Cdd:PLN03091   12 LRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQ 91

                          90       100
                  ....*....|....*....|....*...
gi 1333114720 106 MAAQLPGRTDNEIKNYWNTRMKR--RQR 131
Cdd:PLN03091   92 IAAQLPGRTDNEIKNLWNSCLKKklRQR 119
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 26-129 5.25e-18

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 86.77  E-value: 5.25e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333114720  26 LKKGPWTTAEDGILIEYVQKHGEGNWNAVQKHTGLaRCGKSCRLRWANHLRPNLKKGSFSQEEERLIIELHAKLGNKWAR 105
Cdd:COG5147    18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLIS-STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWST 96

                          90       100
                  ....*....|....*....|....
gi 1333114720 106 MAAQLPGRTDNEIKNYWNTRMKRR 129
Cdd:COG5147    97 IADYKDRRTAQQCVERYVNTLEDL 120
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 81-124 2.04e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 72.92  E-value: 2.04e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1333114720  81 KGSFSQEEERLIIELHAKLGNKWARMAAQLPGRTDNEIKNYWNT 124
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
81-128 5.97e-13

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 63.01  E-value: 5.97e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1333114720   81 KGSFSQEEERLIIELHAKLG-NKWARMAAQLPGRTDNEIKNYWNTRMKR 128
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 83-124 1.38e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 59.13  E-value: 1.38e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1333114720  83 SFSQEEERLIIELHAKLG-NKWARMAAQLPGRTDNEIKNYWNT 124
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRN 43
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 26-131 3.98e-45

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 164.38  E-value: 3.98e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333114720  26 LKKGPWTTAEDGILIEYVQKHGEGNWNAVQKHTGLARCGKSCRLRWANHLRPNLKKGSFSQEEERLIIELHAKLGNKWAR 105
Cdd:PLN03091   12 LRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQ 91

                          90       100
                  ....*....|....*....|....*...
gi 1333114720 106 MAAQLPGRTDNEIKNYWNTRMKR--RQR 131
Cdd:PLN03091   92 IAAQLPGRTDNEIKNLWNSCLKKklRQR 119
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 25-129 4.23e-41

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 147.92  E-value: 4.23e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333114720  25 ALKKGPWTTAEDGILIEYVQKHGEGNWNAVQKHTGLARCGKSCRLRWANHLRPNLKKGSFSQEEERLIIELHAKLGNKWA 104
Cdd:PLN03212   22 GMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWS 101

                          90       100
                  ....*....|....*....|....*
gi 1333114720 105 RMAAQLPGRTDNEIKNYWNTRMKRR 129
Cdd:PLN03212  102 LIAGRIPGRTDNEIKNYWNTHLRKK 126
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 26-129 5.25e-18

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 86.77  E-value: 5.25e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333114720  26 LKKGPWTTAEDGILIEYVQKHGEGNWNAVQKHTGLaRCGKSCRLRWANHLRPNLKKGSFSQEEERLIIELHAKLGNKWAR 105
Cdd:COG5147    18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLIS-STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWST 96

                          90       100
                  ....*....|....*....|....
gi 1333114720 106 MAAQLPGRTDNEIKNYWNTRMKRR 129
Cdd:COG5147    97 IADYKDRRTAQQCVERYVNTLEDL 120
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 81-124 2.04e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 72.92  E-value: 2.04e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1333114720  81 KGSFSQEEERLIIELHAKLGNKWARMAAQLPGRTDNEIKNYWNT 124
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
81-128 5.97e-13

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 63.01  E-value: 5.97e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1333114720   81 KGSFSQEEERLIIELHAKLG-NKWARMAAQLPGRTDNEIKNYWNTRMKR 128
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 31-90 7.45e-13

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 63.10  E-value: 7.45e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1333114720  31 WTTAEDGILIEYVQKHGeGNWNAVQKHTGlARCGKSCRLRWANHLRPNLKKGSFSQEEER 90
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPKISRGPWSKEEDQ 58
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 28-75 1.09e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 1.09e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1333114720  28 KGPWTTAEDGILIEYVQKHGeGNWNAVQKHTGLaRCGKSCRLRWANHL 75
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLPG-RTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
28-77 6.61e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 60.32  E-value: 6.61e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1333114720   28 KGPWTTAEDGILIEYVQKHGEGNWNAVQKHTGLaRCGKSCRLRWANHLRP 77
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPG-RTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 83-124 1.38e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 59.13  E-value: 1.38e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1333114720  83 SFSQEEERLIIELHAKLG-NKWARMAAQLPGRTDNEIKNYWNT 124
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRN 43
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 30-75 6.32e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 57.20  E-value: 6.32e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1333114720  30 PWTTAEDGILIEYVQKHGEGNWNAVQKHTGLaRCGKSCRLRWANHL 75
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPG-RTPKQCRERWRNLL 45
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 30-57 2.67e-06

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 44.48  E-value: 2.67e-06
                          10        20
                  ....*....|....*....|....*...
gi 1333114720  30 PWTTAEDGILIEYVQKHGEGNWNAVQKH 57
Cdd:cd11660     2 KWTDEEDEALVEGVEKYGVGNWAKILKD 29
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 84-127 2.07e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 42.30  E-value: 2.07e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1333114720  84 FSQEEERLIIELHAKLGNKWARMAAQLPGRTDNEIKNYWNTRMK 127
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLN 44
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
 77-116 7.66e-03

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 34.59  E-value: 7.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1333114720  77 PNLKKGSFSQEEERLIIELHAKLGNKWaRMAAQLPGRTDN 116
Cdd:cd11659     1 PSIKKTEWTREEDEKLLHLAKLLPTQW-RTIAPIVGRTAQ 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH