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Conserved domains on  [gi|1332396|gb|AAB00807|]
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ZZ:beta-Gal' IgG-binding fusion protein, partial [Cloning vector pKP497]

Protein Classification

immunoglobulin G-binding protein A( domain architecture ID 10491241)

immunoglobulin G-binding protein A is a cell-wall-bound pathogenicity factor that avidly binds the Fc region of immunoglobulins from most mammalian species in a non-specific aggregation reaction that can lead to host tissue damage

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bgal_small_N super family cl46900
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 133-186 3.24e-27

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


The actual alignment was detected with superfamily member PRK09525:

Pssm-ID: 481240 [Multi-domain]  Cd Length: 1027  Bit Score: 108.48  E-value: 3.24e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1332396    133 SLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWR 186
Cdd:PRK09525    7 SLAQILARRDWENPGVTQLNRLPAHPPFASWRNSEAARDDRPSQQRQSLNGEWR 60
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 10-60 1.90e-20

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


:

Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 80.67  E-value: 1.90e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1332396     10 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 60
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 68-118 1.90e-20

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


:

Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 80.67  E-value: 1.90e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1332396     68 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 118
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
133-186 3.24e-27

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 108.48  E-value: 3.24e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1332396    133 SLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWR 186
Cdd:PRK09525    7 SLAQILARRDWENPGVTQLNRLPAHPPFASWRNSEAARDDRPSQQRQSLNGEWR 60
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 10-60 1.90e-20

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 80.67  E-value: 1.90e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1332396     10 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 60
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 68-118 1.90e-20

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 80.67  E-value: 1.90e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1332396     68 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 118
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
133-186 3.24e-27

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 108.48  E-value: 3.24e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1332396    133 SLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWR 186
Cdd:PRK09525    7 SLAQILARRDWENPGVTQLNRLPAHPPFASWRNSEAARDDRPSQQRQSLNGEWR 60
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 10-60 1.90e-20

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 80.67  E-value: 1.90e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1332396     10 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 60
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
B pfam02216
B domain; This family contains the B domain of Staphylococcal protein A, which specifically ...
 68-118 1.90e-20

B domain; This family contains the B domain of Staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.


Pssm-ID: 396685 [Multi-domain]  Cd Length: 51  Bit Score: 80.67  E-value: 1.90e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1332396     68 KFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDA 118
Cdd:pfam02216   1 DYNKAQQNAFYQVLHLPNLNEEQRNGFIQSLKDDPSQSQNVLGEAKKLNDS 51
ebgA PRK10340
cryptic beta-D-galactosidase subunit alpha; Reviewed
 143-191 1.79e-03

cryptic beta-D-galactosidase subunit alpha; Reviewed


Pssm-ID: 236673 [Multi-domain]  Cd Length: 1021  Bit Score: 38.89  E-value: 1.79e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1332396    143 WENPGVTQLNRLAAHPPFASWRNSEEARTDRP--SQQLRSLNGEWRLmRYF 191
Cdd:PRK10340    4 WENIQLTHENRLAPRAYFFSYDSVAQARTFARetSSLFLLLSGQWNF-HFF 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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