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Conserved domains on  [gi|13279155|gb|AAH04296|]
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BICD2 protein, partial [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BicD super family cl25513
Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled ...
 1-563 0e+00

Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled domains and are involved in dynein-mediated minus end-directed transport from the Golgi apparatus to the endoplasmic reticulum (ER). For full functioning they bind with GSK-3beta pfam05350 to maintain the anchoring of microtubules to the centromere. It appears that amino-acid residues 437-617 of BicD and the kinase activity of GSK-3 are necessary for the formation of a complex between BicD and GSK-3beta in intact cells.


The actual alignment was detected with superfamily member pfam09730:

Pssm-ID: 462863 [Multi-domain]  Cd Length: 717  Bit Score: 824.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155     1 QLEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDD---AAEPNNDAEALvNGFEHG--GLAKLPL 75
Cdd:pfam09730 157 QLDEALETLKTEREQKNSLRKELSHYMTLNDFDYVSHLSISLDGLKFSEDegaGTEPNNDGEAM-DGGENGggGLKNSGL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    76 DNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTEN 155
Cdd:pfam09730 236 DNRTSTPRKSEVFPPAPSLVSDLLSELNISEIQKLKQQLIQVEREKVSLLSTLQESQKQLEQAKGALSEQQEKVNRLTEN 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   156 LSALRRLQASKERQTALDNEKDRDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGR 235
Cdd:pfam09730 316 LEAMRGLQASKERQDALDSEKDRDSHEDGDYYEVDINGPEILECKYRVAVEEAGELREELKALKARYNTLEERYKEEKTR 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   236 YEAEGQALTEKVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVM 315
Cdd:pfam09730 396 WEAEAQDLAEKIRQLEKASHQDQERIAHLEKELGKTRKVAGESEGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVM 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   316 LDYYREGQGGAGRtspggRTSPEARGRRSPILLPKGLLAPEAGRADGGtGDSSPSPGSSLPSPLSDPRREPMNIYNLIAI 395
Cdd:pfam09730 476 LDYYREGAGARAR-----KSHQEPRGLRSPRLLTRGLFMGEVGTADTT-SNSPSPCSSCPGSPTSDFRREPMNIYNLVAI 549

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   396 IRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKS 475
Cdd:pfam09730 550 IRDQIKHLQVAVDRTTELSRQRGAALELSTESDKDKEALMEEILKLKSLLSTKREQIATLRTVLKANKQTAEVALANLKS 629

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   476 KYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALT 555
Cdd:pfam09730 630 KYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALT 709


                  ....*...
gi 13279155   556 QRLELLEL 563
Cdd:pfam09730 710 QRLEDLEF 717
 
Name Accession Description Interval E-value
BicD pfam09730
Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled ...
 1-563 0e+00

Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled domains and are involved in dynein-mediated minus end-directed transport from the Golgi apparatus to the endoplasmic reticulum (ER). For full functioning they bind with GSK-3beta pfam05350 to maintain the anchoring of microtubules to the centromere. It appears that amino-acid residues 437-617 of BicD and the kinase activity of GSK-3 are necessary for the formation of a complex between BicD and GSK-3beta in intact cells.


Pssm-ID: 462863 [Multi-domain]  Cd Length: 717  Bit Score: 824.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155     1 QLEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDD---AAEPNNDAEALvNGFEHG--GLAKLPL 75
Cdd:pfam09730 157 QLDEALETLKTEREQKNSLRKELSHYMTLNDFDYVSHLSISLDGLKFSEDegaGTEPNNDGEAM-DGGENGggGLKNSGL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    76 DNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTEN 155
Cdd:pfam09730 236 DNRTSTPRKSEVFPPAPSLVSDLLSELNISEIQKLKQQLIQVEREKVSLLSTLQESQKQLEQAKGALSEQQEKVNRLTEN 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   156 LSALRRLQASKERQTALDNEKDRDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGR 235
Cdd:pfam09730 316 LEAMRGLQASKERQDALDSEKDRDSHEDGDYYEVDINGPEILECKYRVAVEEAGELREELKALKARYNTLEERYKEEKTR 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   236 YEAEGQALTEKVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVM 315
Cdd:pfam09730 396 WEAEAQDLAEKIRQLEKASHQDQERIAHLEKELGKTRKVAGESEGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVM 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   316 LDYYREGQGGAGRtspggRTSPEARGRRSPILLPKGLLAPEAGRADGGtGDSSPSPGSSLPSPLSDPRREPMNIYNLIAI 395
Cdd:pfam09730 476 LDYYREGAGARAR-----KSHQEPRGLRSPRLLTRGLFMGEVGTADTT-SNSPSPCSSCPGSPTSDFRREPMNIYNLVAI 549

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   396 IRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKS 475
Cdd:pfam09730 550 IRDQIKHLQVAVDRTTELSRQRGAALELSTESDKDKEALMEEILKLKSLLSTKREQIATLRTVLKANKQTAEVALANLKS 629

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   476 KYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALT 555
Cdd:pfam09730 630 KYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALT 709


                  ....*...
gi 13279155   556 QRLELLEL 563
Cdd:pfam09730 710 QRLEDLEF 717
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 106-282 7.26e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 7.26e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 106 EIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDGD 185
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 186 YYEVDIngpEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLE 265
Cdd:COG1196 320 ELEEEL---AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396

                       170
                ....*....|....*..
gi 13279155 266 KELKKVSDVAGETQGSL 282
Cdd:COG1196 397 ELAAQLEELEEAEEALL 413
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 106-270 1.24e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.60  E-value: 1.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    106 EIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDGD 185
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    186 YYEVDIngpEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEkgryEAEGQALTEKVSLLEKASRQDRELLARLE 265
Cdd:TIGR02168  320 ELEAQL---EELESKLDELAEELAELEEKLEELKEELESLEAELEEL----EAELEELESRLEELEEQLETLRSKVAQLE 392


                   ....*
gi 13279155    266 KELKK 270
Cdd:TIGR02168  393 LQIAS 397
PRK09039 PRK09039
peptidoglycan -binding protein;
99-252 6.26e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 39.18  E-value: 6.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   99 LSELNiSEIQKLKQQLMQMEREKAGL---LATLQDTQKQLEHTR-----------GSLSEQQEKVTRLTENLSALRRLQA 164
Cdd:PRK09039  55 LDRLN-SQIAELADLLSLERQGNQDLqdsVANLRASLSAAEAERsrlqallaelaGAGAAAEGRAGELAQELDSEKQVSA 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155  165 SKERQTALDNEKdrdshedgdyyevdingpeilackyhvaVAEageLREQLKALRSTHEAREAQHAEEKGRYEAEGQ--- 241
Cdd:PRK09039 134 RALAQVELLNQQ----------------------------IAA---LRRQLAALEAALDASEKRDRESQAKIADLGRrln 182

                        170
                 ....*....|..
gi 13279155  242 -ALTEKVSLLEK 252
Cdd:PRK09039 183 vALAQRVQELNR 194
 
Name Accession Description Interval E-value
BicD pfam09730
Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled ...
 1-563 0e+00

Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled domains and are involved in dynein-mediated minus end-directed transport from the Golgi apparatus to the endoplasmic reticulum (ER). For full functioning they bind with GSK-3beta pfam05350 to maintain the anchoring of microtubules to the centromere. It appears that amino-acid residues 437-617 of BicD and the kinase activity of GSK-3 are necessary for the formation of a complex between BicD and GSK-3beta in intact cells.


Pssm-ID: 462863 [Multi-domain]  Cd Length: 717  Bit Score: 824.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155     1 QLEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDD---AAEPNNDAEALvNGFEHG--GLAKLPL 75
Cdd:pfam09730 157 QLDEALETLKTEREQKNSLRKELSHYMTLNDFDYVSHLSISLDGLKFSEDegaGTEPNNDGEAM-DGGENGggGLKNSGL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    76 DNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTEN 155
Cdd:pfam09730 236 DNRTSTPRKSEVFPPAPSLVSDLLSELNISEIQKLKQQLIQVEREKVSLLSTLQESQKQLEQAKGALSEQQEKVNRLTEN 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   156 LSALRRLQASKERQTALDNEKDRDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGR 235
Cdd:pfam09730 316 LEAMRGLQASKERQDALDSEKDRDSHEDGDYYEVDINGPEILECKYRVAVEEAGELREELKALKARYNTLEERYKEEKTR 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   236 YEAEGQALTEKVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVM 315
Cdd:pfam09730 396 WEAEAQDLAEKIRQLEKASHQDQERIAHLEKELGKTRKVAGESEGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVM 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   316 LDYYREGQGGAGRtspggRTSPEARGRRSPILLPKGLLAPEAGRADGGtGDSSPSPGSSLPSPLSDPRREPMNIYNLIAI 395
Cdd:pfam09730 476 LDYYREGAGARAR-----KSHQEPRGLRSPRLLTRGLFMGEVGTADTT-SNSPSPCSSCPGSPTSDFRREPMNIYNLVAI 549

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   396 IRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKS 475
Cdd:pfam09730 550 IRDQIKHLQVAVDRTTELSRQRGAALELSTESDKDKEALMEEILKLKSLLSTKREQIATLRTVLKANKQTAEVALANLKS 629

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   476 KYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALT 555
Cdd:pfam09730 630 KYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALT 709


                  ....*...
gi 13279155   556 QRLELLEL 563
Cdd:pfam09730 710 QRLEDLEF 717
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 106-282 7.26e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 7.26e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 106 EIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDGD 185
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 186 YYEVDIngpEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLE 265
Cdd:COG1196 320 ELEEEL---AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396

                       170
                ....*....|....*..
gi 13279155 266 KELKKVSDVAGETQGSL 282
Cdd:COG1196 397 ELAAQLEELEEAEEALL 413
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 106-270 1.24e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.60  E-value: 1.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    106 EIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDGD 185
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    186 YYEVDIngpEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEkgryEAEGQALTEKVSLLEKASRQDRELLARLE 265
Cdd:TIGR02168  320 ELEAQL---EELESKLDELAEELAELEEKLEELKEELESLEAELEEL----EAELEELESRLEELEEQLETLRSKVAQLE 392


                   ....*
gi 13279155    266 KELKK 270
Cdd:TIGR02168  393 LQIAS 397
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 105-299 1.54e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.48  E-value: 1.54e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 105 SEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDG 184
Cdd:COG1196 267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 185 dyyevdingpEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARL 264
Cdd:COG1196 347 ----------EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                       170       180       190
                ....*....|....*....|....*....|....*
gi 13279155 265 EKELKKVSDVAGETQGSLSVAQDELVTFSEELANL 299
Cdd:COG1196 417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 105-270 3.35e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 48.38  E-value: 3.35e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 105 SEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALR-RLQASKERQTALDNEKDRDSHED 183
Cdd:COG1579  17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEaRIKKYEEQLGNVRNNKEYEALQK 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 184 gdyyEVDINGPEILACKYHV--AVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASrqdRELL 261
Cdd:COG1579  97 ----EIESLKRRISDLEDEIleLMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAER---EELA 169


                ....*....
gi 13279155 262 ARLEKELKK 270
Cdd:COG1579 170 AKIPPELLA 178
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 106-273 2.56e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.56e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 106 EIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRR----LQASKERQTA---------- 171
Cdd:COG4942  35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKeiaeLRAELEAQKEelaellraly 114

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 172 -----------LDNEKDRDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEG 240
Cdd:COG4942 115 rlgrqpplallLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALK 194

                       170       180       190
                ....*....|....*....|....*....|...
gi 13279155 241 QALTEKVSLLEKASRQDRELLARLEKELKKVSD 273
Cdd:COG4942 195 AERQKLLARLEKELAELAAELAELQQEAEELEA 227
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 105-299 2.86e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.86e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 105 SEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSAL--------RRLQASKERQTALDNEK 176
Cdd:COG4942  20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALeqelaaleAELAELEKEIAELRAEL 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 177 DRDSHEDGD-----YYEVDINGPEILackyhVAVAEAGELREQLKALRSTHEAREAQHAEekgrYEAEGQALTEKVSLLE 251
Cdd:COG4942 100 EAQKEELAEllralYRLGRQPPLALL-----LSPEDFLDAVRRLQYLKYLAPARREQAEE----LRADLAELAALRAELE 170

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 13279155 252 KASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANL 299
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 105-299 3.12e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 3.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    105 SEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDG 184
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    185 DYYEVDINGpeiLACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTE-KVSLLEKASRQDRELLAR 263
Cdd:TIGR02168  375 EELEEQLET---LRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEE 451

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 13279155    264 LEKELKKVSDVAGETQGSLSVAQDELVTFSEELANL 299
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQL 487
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 396-575 6.96e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 6.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    396 IRDQIKHLQAA--VDRTTELSRQRIASQElgpavdkDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANL 473
Cdd:TIGR02168  218 LKAELRELELAllVLRLEELREELEELQE-------ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    474 KSKYeNEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLA 553
Cdd:TIGR02168  291 YALA-NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369

                          170       180
                   ....*....|....*....|..
gi 13279155    554 LTQRLELLELDHEQTRRGRAKA 575
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQL 391
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 95-300 1.37e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 1.37e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155  95 VSDLLSELNiSEIQKLKQQ---------LMQMEREKAGLLATLQDTQKQLEHTRgSLSEQQEKVTRLTENLSALRRLQAS 165
Cdd:COG1196 191 LEDILGELE-RQLEPLERQaekaeryreLKEELKELEAELLLLKLRELEAELEE-LEAELEELEAELEELEAELAELEAE 268

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 166 KERQTALDNEKDRDSHEDGDyyevdingpeilacKYHVAVAEAGELREQLKALrsthEAREAQHAEEKGRYEAEGQALTE 245
Cdd:COG1196 269 LEELRLELEELELELEEAQA--------------EEYELLAELARLEQDIARL----EERRRELEERLEELEEELAELEE 330

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 13279155 246 KVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLY 300
Cdd:COG1196 331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
112-299 1.51e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 1.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155  112 QQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTEnLSALRRLQASKERQTALDNEKDRdsHEDgdyyEVDI 191
Cdd:COG4913  241 HEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRL-WFAQRRLELLEAELEELRAELAR--LEA----ELER 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155  192 NGPEILACKYHVAVAEA------GELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSL----LEKASRQDRELL 261
Cdd:COG4913  314 LEARLDALREELDELEAqirgngGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPAsaeeFAALRAEAAALL 393

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 13279155  262 ARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANL 299
Cdd:COG4913  394 EALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 105-296 1.83e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.58  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    105 SEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALR-RLQASKERQTALDNEKDRDSHED 183
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    184 GDYyEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAR----EAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRE 259
Cdd:TIGR02168  757 TEL-EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkalREALDELRAELTLLNEEAANLRERLESLERRIAA 835

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 13279155    260 LLARLEkELKKVSDVAGETQGSLSVAQDELVTFSEEL 296
Cdd:TIGR02168  836 TERRLE-DLEEQIEELSEDIESLAAEIEELEELIEEL 871
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
107-566 2.19e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 2.19e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 107 IQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALR-RLQASKERQTALDNEKDRDSHEDGD 185
Cdd:COG4717  48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEeELEELEAELEELREELEKLEKLLQL 127

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 186 YYevdingpeiLACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLE 265
Cdd:COG4717 128 LP---------LYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLA 198

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 266 KELKKVSDVAGETQGSLSVAQDELVTFSEELANLyhhvcmcNNETPNRVMLDYYREGQGGAGRTSPGGRTSPEARGRRSP 345
Cdd:COG4717 199 EELEELQQRLAELEEELEEAQEELEELEEELEQL-------ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSL 271

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 346 ILLPKGLLAPEAGRADGGtgdssPSPGSSLPSPLSDPRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIasqelgp 425
Cdd:COG4717 272 ILTIAGVLFLVLGLLALL-----FLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEEL------- 339

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 426 avdkdkEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYE-NEKAMVTETMMKLRNELKALKE--DA 502
Cdd:COG4717 340 ------LELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElRAALEQAEEYQELKEELEELEEqlEE 413

                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13279155 503 ATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLnsllrmaIQQKLALTQRLELLELDHE 566
Cdd:COG4717 414 LLGELEELLEALDEEELEEELEELEEELEELEEELEEL-------REELAELEAELEQLEEDGE 470
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 106-299 2.44e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.09  E-value: 2.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155  106 EIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRgslsEQQEKVTRLTENLSAL-------RRLQASKERQTALDNEKDR 178
Cdd:COG3096  837 ELAALRQRRSELERELAQHRAQEQQLRQQLDQLK----EQLQLLNKLLPQANLLadetladRLEELREELDAAQEAQAFI 912

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155  179 DSHEDG--------DYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKV-SL 249
Cdd:COG3096  913 QQHGKAlaqleplvAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLNEKLrAR 992

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 13279155  250 LEKASRQDRELLARLEKELKKVSD---VAGETQGSLSVAQDELVTFSEELANL 299
Cdd:COG3096  993 LEQAEEARREAREQLRQAQAQYSQynqVLASLKSSRDAKQQTLQELEQELEEL 1045
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 105-289 3.91e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 39.81  E-value: 3.91e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 105 SEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSA-LRRLQASKERQTALDNEKDRDSHED 183
Cdd:COG3883  37 AELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErARALYRSGGSVSYLDVLLGSESFSD 116

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155 184 gdyyevDINGPEILAckyhVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLAR 263
Cdd:COG3883 117 ------FLDRLSALS----KIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQ 186

                       170       180
                ....*....|....*....|....*.
gi 13279155 264 LEKELKKVSDVAGETQGSLSVAQDEL 289
Cdd:COG3883 187 LSAEEAAAEAQLAELEAELAAAEAAA 212
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 99-274 4.75e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 4.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155     99 LSELNiSEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQ-TALDNEKD 177
Cdd:TIGR02168  805 LDELR-AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESElEALLNERA 883

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    178 ---RDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGR----YEAEGQALTEKVSLL 250
Cdd:TIGR02168  884 sleEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlseeYSLTLEEAEALENKI 963

                          170       180
                   ....*....|....*....|....
gi 13279155    251 EKASRQDRELLARLEKELKKVSDV 274
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKIKELGPV 987
PRK09039 PRK09039
peptidoglycan -binding protein;
99-252 6.26e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 39.18  E-value: 6.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155   99 LSELNiSEIQKLKQQLMQMEREKAGL---LATLQDTQKQLEHTR-----------GSLSEQQEKVTRLTENLSALRRLQA 164
Cdd:PRK09039  55 LDRLN-SQIAELADLLSLERQGNQDLqdsVANLRASLSAAEAERsrlqallaelaGAGAAAEGRAGELAQELDSEKQVSA 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155  165 SKERQTALDNEKdrdshedgdyyevdingpeilackyhvaVAEageLREQLKALRSTHEAREAQHAEEKGRYEAEGQ--- 241
Cdd:PRK09039 134 RALAQVELLNQQ----------------------------IAA---LRRQLAALEAALDASEKRDRESQAKIADLGRrln 182

                        170
                 ....*....|..
gi 13279155  242 -ALTEKVSLLEK 252
Cdd:PRK09039 183 vALAQRVQELNR 194
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 388-576 7.34e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 7.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    388 NIYNLIAIIRDQIKHLQAAVDR-----------TTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQittlR 456
Cdd:TIGR02168  292 ALANEISRLEQQKQILRERLANlerqleeleaqLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----L 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13279155    457 TVLKANKQTAEVALANLKSKY---ENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEyiTQLDEMQRQLAAA 533
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVaqlELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEEL 445

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 13279155    534 EDEKKTLNSLLRMAIQQKLALTQRLELLELDHEQTRRGRAKAA 576
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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