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Conserved domains on  [gi|13278075|gb|AAH03890|]
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Mrps17 protein [Mus musculus]

Protein Classification

uS17 family ribosomal protein( domain architecture ID 18906663)

uS17 family ribosomal protein such as human small ribosomal subunit protein uS17m, a component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins

CATH:  2.40.50.140
Gene Ontology:  GO:0015935|GO:0005840|GO:0019843|GO:0003735|GO:0006412
PubMed:  24524803|20534711|19616559|11909526
SCOP:  3000135

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_uS17 cd00364
Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins ...
 11-84 6.25e-21

Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins (S4, S17 and S20) that stabilize the entire 5' rRNA domain and increase the global stability of the rRNA structure. uS17 is highly conserved in all three major phylogenetic divisions. In eukaryotes, the S17 ortholog of the cytoplasmic ribosome is called S11 as are those of the mitochondrial and chloroplast ribosomes. uS17 plays a critical role in both subunit assembly and translational fidelity.


:

Pssm-ID: 466775  Cd Length: 73  Bit Score: 79.39  E-value: 6.25e-21
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13278075  11 KWVVGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAEI 84
Cdd:cd00364   1 KILIGVVVSDKMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDEPNECKVGDIVRIGECR-PLSKTKRWVVVEI 73
 
Name Accession Description Interval E-value
Ribosomal_uS17 cd00364
Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins ...
 11-84 6.25e-21

Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins (S4, S17 and S20) that stabilize the entire 5' rRNA domain and increase the global stability of the rRNA structure. uS17 is highly conserved in all three major phylogenetic divisions. In eukaryotes, the S17 ortholog of the cytoplasmic ribosome is called S11 as are those of the mitochondrial and chloroplast ribosomes. uS17 plays a critical role in both subunit assembly and translational fidelity.


Pssm-ID: 466775  Cd Length: 73  Bit Score: 79.39  E-value: 6.25e-21
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13278075  11 KWVVGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAEI 84
Cdd:cd00364   1 KILIGVVVSDKMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDEPNECKVGDIVRIGECR-PLSKTKRWVVVEI 73
Ribosomal_S17 pfam00366
Ribosomal protein S17;
15-83 5.50e-16

Ribosomal protein S17;


Pssm-ID: 459784  Cd Length: 68  Bit Score: 66.64  E-value: 5.50e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13278075    15 GKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAE 83
Cdd:pfam00366   1 GVVVSDKMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDENNECKVGDVVRIGECR-PLSKTKRWVVVE 68
RpsQ COG0186
Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 ...
 7-85 2.72e-10

Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 439956  Cd Length: 87  Bit Score: 52.81  E-value: 2.72e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13278075   7 SVHAKWVVGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLL---RalpvPRSKHVKHELAE 83
Cdd:COG0186   5 RVRRKTLTGVVVSDKMDKTVVVEVERRVKHPLYGKYVRRSKKYHAHDENNECKVGDTVRImetR----PLSKTKRWRVVE 80


                ..
gi 13278075  84 II 85
Cdd:COG0186  81 IV 82
rpsQ PRK05610
30S ribosomal protein S17; Reviewed
 14-85 8.71e-10

30S ribosomal protein S17; Reviewed


Pssm-ID: 235532  Cd Length: 84  Bit Score: 51.31  E-value: 8.71e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 13278075   14 VGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAEII 85
Cdd:PRK05610  10 QGRVVSDKMDKTIVVLVERRVKHPLYGKIVKRSKKYHAHDENNEAKIGDVVRIMETR-PLSKTKRWRLVEIV 80
 
Name Accession Description Interval E-value
Ribosomal_uS17 cd00364
Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins ...
 11-84 6.25e-21

Ribosomal protein uS17; Ribosomal protein uS17 is one of the three primary assembly proteins (S4, S17 and S20) that stabilize the entire 5' rRNA domain and increase the global stability of the rRNA structure. uS17 is highly conserved in all three major phylogenetic divisions. In eukaryotes, the S17 ortholog of the cytoplasmic ribosome is called S11 as are those of the mitochondrial and chloroplast ribosomes. uS17 plays a critical role in both subunit assembly and translational fidelity.


Pssm-ID: 466775  Cd Length: 73  Bit Score: 79.39  E-value: 6.25e-21
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13278075  11 KWVVGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAEI 84
Cdd:cd00364   1 KILIGVVVSDKMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDEPNECKVGDIVRIGECR-PLSKTKRWVVVEI 73
Ribosomal_S17 pfam00366
Ribosomal protein S17;
15-83 5.50e-16

Ribosomal protein S17;


Pssm-ID: 459784  Cd Length: 68  Bit Score: 66.64  E-value: 5.50e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13278075    15 GKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAE 83
Cdd:pfam00366   1 GVVVSDKMDKTVVVRVERLVYHPKYKKYVKRTKKYHAHDENNECKVGDVVRIGECR-PLSKTKRWVVVE 68
RpsQ COG0186
Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 ...
 7-85 2.72e-10

Ribosomal protein S17 [Translation, ribosomal structure and biogenesis]; Ribosomal protein S17 is part of the Pathway/BioSystem: Ribosome 30S subunit


Pssm-ID: 439956  Cd Length: 87  Bit Score: 52.81  E-value: 2.72e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13278075   7 SVHAKWVVGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLL---RalpvPRSKHVKHELAE 83
Cdd:COG0186   5 RVRRKTLTGVVVSDKMDKTVVVEVERRVKHPLYGKYVRRSKKYHAHDENNECKVGDTVRImetR----PLSKTKRWRVVE 80


                ..
gi 13278075  84 II 85
Cdd:COG0186  81 IV 82
rpsQ PRK05610
30S ribosomal protein S17; Reviewed
 14-85 8.71e-10

30S ribosomal protein S17; Reviewed


Pssm-ID: 235532  Cd Length: 84  Bit Score: 51.31  E-value: 8.71e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 13278075   14 VGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAEII 85
Cdd:PRK05610  10 QGRVVSDKMDKTIVVLVERRVKHPLYGKIVKRSKKYHAHDENNEAKIGDVVRIMETR-PLSKTKRWRLVEIV 80
rps17 CHL00142
ribosomal protein S17; Validated
 10-87 5.96e-06

ribosomal protein S17; Validated


Pssm-ID: 177064  Cd Length: 84  Bit Score: 41.18  E-value: 5.96e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 13278075   10 AKWVVGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPvPRSKHVKHELAEIIFK 87
Cdd:CHL00142   3 VKEKIGIVVSNKMNKTIVVAVENRYKHPIYGKIITKTKKYLVHDEENECNIGDQVLIEETR-PLSKTKRWILKEILSK 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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