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Conserved domains on  [gi|1327556140|gb|PMP93411|]
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MAG: protein translocase subunit SecF [Hydrogenobaculum sp.]

Protein Classification

protein translocase subunit SecF( domain architecture ID 11417410)

protein translocase subunit SecF is part of the Sec protein translocase complex; SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA

Gene Ontology:  GO:0015450|GO:0043952
TCDB:  2.A.6.4

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 6-275 2.18e-111

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 323.54  E-value: 2.18e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   6 IHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKDAVVQRTNTGDIiVK 85
Cdd:COG0341     9 IDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFGSDND-VL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  86 IRVGEKPSL-------VEKALNS-IGSFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALA 157
Cdd:COG0341    88 IRTPPLDGEsaeevekVRAALKEaFGDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRFAVGAVVALL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 158 HDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLS 237
Cdd:COG0341   168 HDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQTLSRTINTSLTTLLV 247

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1327556140 238 SLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASALV 275
Cdd:COG0341   248 VLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLL 285
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 6-275 2.18e-111

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 323.54  E-value: 2.18e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   6 IHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKDAVVQRTNTGDIiVK 85
Cdd:COG0341     9 IDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFGSDND-VL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  86 IRVGEKPSL-------VEKALNS-IGSFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALA 157
Cdd:COG0341    88 IRTPPLDGEsaeevekVRAALKEaFGDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRFAVGAVVALL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 158 HDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLS 237
Cdd:COG0341   168 HDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQTLSRTINTSLTTLLV 247

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1327556140 238 SLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASALV 275
Cdd:COG0341   248 VLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLL 285
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 6-275 2.90e-89

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 280.96  E-value: 2.90e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   6 IHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKDAVVQRTNTGDIIVK 85
Cdd:PRK13024  449 IDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSDNNQVL 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  86 IRVGEKPS-----------LVEKALNSIGSFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGIL 154
Cdd:PRK13024  529 VRTYGILSddeeadteivaKLKNALKNDKGGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTFSLGAIL 608

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 155 ALAHDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTV 234
Cdd:PRK13024  609 ALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSINQTLSRTINTSLTT 688

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1327556140 235 FLSSLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASALV 275
Cdd:PRK13024  689 LLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLW 729
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 34-271 4.63e-75

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 229.85  E-value: 4.63e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  34 GLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKDAVVQRT-NTGDIIVKIRV---GEKPSLVEKALNSIG----SF 105
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFgSSHTIMIRIPTldtEQSEELREALEEALKnvdpDA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 106 QLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALAHDVFIVVGAYSWTYKEVSLDVLASILVV 185
Cdd:TIGR00966  81 EIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 186 AGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSDISFAFLIGVVVGTL 265
Cdd:TIGR00966 161 IGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVGTY 240


                  ....*.
gi 1327556140 266 SSIFVA 271
Cdd:TIGR00966 241 SSIFIA 246
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 95-275 3.10e-58

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 184.73  E-value: 3.10e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  95 VEKALNSIG-SFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALAHDVFIVVGAYSWTYKE 173
Cdd:pfam02355   2 VEALLKNVGpDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 174 VSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSDIS 253
Cdd:pfam02355  82 VDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFS 161

                         170       180
                  ....*....|....*....|..
gi 1327556140 254 FAFLIGVVVGTLSSIFVASALV 275
Cdd:pfam02355 162 LALLVGVIVGTYSSIFIASPIL 183
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 6-275 2.18e-111

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 323.54  E-value: 2.18e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   6 IHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKDAVVQRTNTGDIiVK 85
Cdd:COG0341     9 IDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFGSDND-VL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  86 IRVGEKPSL-------VEKALNS-IGSFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALA 157
Cdd:COG0341    88 IRTPPLDGEsaeevekVRAALKEaFGDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEWRFAVGAVVALL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 158 HDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLS 237
Cdd:COG0341   168 HDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQTLSRTINTSLTTLLV 247

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1327556140 238 SLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASALV 275
Cdd:COG0341   248 VLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLL 285
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 6-275 2.90e-89

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 280.96  E-value: 2.90e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   6 IHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKDAVVQRTNTGDIIVK 85
Cdd:PRK13024  449 IDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSDNNQVL 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  86 IRVGEKPS-----------LVEKALNSIGSFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGIL 154
Cdd:PRK13024  529 VRTYGILSddeeadteivaKLKNALKNDKGGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTFSLGAIL 608

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 155 ALAHDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTV 234
Cdd:PRK13024  609 ALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSINQTLSRTINTSLTT 688

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1327556140 235 FLSSLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASALV 275
Cdd:PRK13024  689 LLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLW 729
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 34-271 4.63e-75

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 229.85  E-value: 4.63e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  34 GLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKDAVVQRT-NTGDIIVKIRV---GEKPSLVEKALNSIG----SF 105
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFgSSHTIMIRIPTldtEQSEELREALEEALKnvdpDA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 106 QLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALAHDVFIVVGAYSWTYKEVSLDVLASILVV 185
Cdd:TIGR00966  81 EIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 186 AGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSDISFAFLIGVVVGTL 265
Cdd:TIGR00966 161 IGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVGTY 240


                  ....*.
gi 1327556140 266 SSIFVA 271
Cdd:TIGR00966 241 SSIFIA 246
PRK14726 PRK14726
protein translocase subunit SecDF;
6-274 1.41e-62

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 211.50  E-value: 1.41e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   6 IHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQTPVS-VKQVDDALYKVNIKDAVVQRTNT-GDII 83
Cdd:PRK14726  547 IRFMGIRRYVFTLSAALSLASLVLFATVGLNLGIDFTGGSLIEVRAKQGNAdIADIRARLNELNLGEVQVERFGSpRDAL 626

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  84 VKIRV---GEKP-----SLVEKALNSIGSFQllQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILA 155
Cdd:PRK14726  627 IRIASqdgGENAeqsavTLVRGELEDDYDFR--RVEVVGPAVSGELTMAATLGVLAALAAILIYIWIRFEWQFAVGAIIA 704

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 156 LAHDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVF 235
Cdd:PRK14726  705 TLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKMPLPILIDASINQTLSRTVLTSATTL 784

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1327556140 236 LSSLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASAL 274
Cdd:PRK14726  785 LALLALYLFGGEVIRSFTFAMLFGVAVGTFSSIYIAAPV 823
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 95-275 3.10e-58

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 184.73  E-value: 3.10e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  95 VEKALNSIG-SFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALAHDVFIVVGAYSWTYKE 173
Cdd:pfam02355   2 VEALLKNVGpDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 174 VSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSDIS 253
Cdd:pfam02355  82 VDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFS 161

                         170       180
                  ....*....|....*....|..
gi 1327556140 254 FAFLIGVVVGTLSSIFVASALV 275
Cdd:pfam02355 162 LALLVGVIVGTYSSIFIASPIL 183
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 3-274 6.09e-50

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 166.95  E-value: 6.09e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   3 IKYIHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQTPVSVKQVDDALYKVNIKD-AVVQRTNTGD 81
Cdd:PRK13021    1 MKNINLTKWRYISSAISIVLMLLSLTIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPLLNAAYQQEvSVISASEPGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  82 IIVKIRV----GEKPSLVEKALNSIGSFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALA 157
Cdd:PRK13021   81 WVLRYAPadtaQSNVDIQQALAPLGTEVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFALV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 158 HDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLS 237
Cdd:PRK13021  161 HDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIVATFSRTMVTSGTTLMT 240

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1327556140 238 SLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASAL 274
Cdd:PRK13021  241 VGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSL 277
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
 113-268 3.32e-43

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 146.25  E-value: 3.32e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 113 IGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALAHDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITD 192
Cdd:TIGR00916  37 VGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILILGVLSLFGATLTLPGIAGLLTIIGYSVDD 116

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1327556140 193 TVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSDISFAFLIGVVVGTLSSI 268
Cdd:TIGR00916 117 TVVIFDRIREELRKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
PRK13023 PRK13023
protein translocase subunit SecDF;
3-275 9.53e-37

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 138.60  E-value: 9.53e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140   3 IKYIHFIKYRYYSYVISIILILLSAFSLYTRGLNLGLDFTGGTMLEVRFQT-PVSVKQVDDALYKVNIKDA-VVQRTNTG 80
Cdd:PRK13023  450 VTHIPFMRLQFVTLGISVLACAIVVALFVNIGFNYGIDFRGGSMVELQARNgDANLEDINERLAELNIDSArVLPAKSPR 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  81 DIIVKIRVGEKPSLVEK--ALNSIGSFQ---LLQREDI-GSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGIL 154
Cdd:PRK13023  530 SALVIIGSQEVGDDAEQtvAVKLRGEFEqdySFQRVDVvGPTVSEQLSRAGVLAVILSLIGIFIYVWFRFRWQLALGAVL 609

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 155 ALAHDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTV 234
Cdd:PRK13023  610 STLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSAPLPAIIDASINQTLSRTLLTSFVT 689

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1327556140 235 FLSSLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASALV 275
Cdd:PRK13023  690 FLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLL 730
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 113-275 1.49e-23

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 100.70  E-value: 1.49e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  113 IGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGILALAHDVF----IVVGAYSWTYK-EVSLDVLASILVVAG 187
Cdd:PRK12911  1224 VSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALIHDLLatcaVLVALHFFLQKiQIDLQAIGALMTVLG 1303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  188 YSITDTVVVFDRIRENLKLRKGMDLSEIINLSVNQNIVRTIMTSSTVfLSSLGLYLF-GGNVLSDISFAFLIGVVVGTLS 266
Cdd:PRK12911  1304 YSLNNTLIIFDRIREDRQEKLFTPMPILINDALQKTLGRTVMTTATT-LSVLLILLFvGGGSIFNFAFIMTIGILLGTLS 1382


                   ....*....
gi 1327556140  267 SIFVASALV 275
Cdd:PRK12911  1383 SLYIAPPLL 1391
PRK08578 PRK08578
preprotein translocase subunit SecF; Reviewed
 21-259 9.81e-12

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 236302 [Multi-domain]  Cd Length: 292  Bit Score: 64.18  E-value: 9.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  21 ILILLSAFSLYTRGLNLGLDFTGGTMLEVrFQTPVSVKQVDDALYKVNIKDAVVQRTNTGDIIVKIRVGEKPSLVEKAL- 99
Cdd:PRK08578   28 LLLLGGTFATTGSPVKLGIDFTGGTEITI-QTNDASPDELESALSGEPGVDVRKGSGNGYIITFGSGDDTDVDKLADAVk 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 100 -----NSIGSFQLLQREdIGSVVSGELRKKAVWAIITALVG--ILIYLSFRyEFLFALGGILALAHDVFIVVGAYSWTYK 172
Cdd:PRK08578  107 effnvDSISELNYSEKQ-IGPTFGSQFQEQALKAVGFAFIGmaVVVFLIFR-TPVPSLAVILSAFSDIIIALALMNLFGI 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 173 EVSLDVLASILVVAGYSITDTVVVFDRIrenlkLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSDI 252
Cdd:PRK08578  185 ELSLATVAALLMLIGYSVDSDILLTTRV-----LKRRGTFDESIKRAMRTGITMTLTTIAAMAVLYIVSTIPQAEVLANI 259


                  ....*..
gi 1327556140 253 SFAFLIG 259
Cdd:PRK08578  260 AAVLIFG 266
Sec_GG pfam07549
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export ...
 29-55 5.19e-09

SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins.


Pssm-ID: 462205 [Multi-domain]  Cd Length: 27  Bit Score: 50.75  E-value: 5.19e-09
                          10        20
                  ....*....|....*....|....*..
gi 1327556140  29 SLYTRGLNLGLDFTGGTMLEVRFQTPV 55
Cdd:pfam07549   1 SLFTRGLNLGLDFTGGTVIELQFDQPV 27
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 104-275 1.18e-07

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 52.29  E-value: 1.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 104 SFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEfLFALGGILALAHDVFIVVGAYSWTYKEVSLDVLASIL 183
Cdd:TIGR01129 229 PLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYR-LFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLI 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 184 VVAGYSITDTVVVFDRIREnlKLRKGMDLSEIINLSvNQNIVRTIMTSS-TVFLSSLGLYLFGGNVLSDISFAFLIGVVV 262
Cdd:TIGR01129 308 LTIGMAVDANVLIYERIKE--ELRLGKSVRQAIEAG-FERAFSTIFDANiTTLIAALILYVFGTGPVKGFAVTLAIGIIA 384

                         170
                  ....*....|...
gi 1327556140 263 GTLSSIFVASALV 275
Cdd:TIGR01129 385 SLFTALVFTRLLL 397
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 123-275 3.88e-05

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 44.72  E-value: 3.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 123 KKAVWAIITALVGILIYLSFRYEfLFALGGILALAHDVFIVVGAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIRE 202
Cdd:COG0342   271 EKGLIAGLIGLLLVALFMLLYYR-LPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIRE 349

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1327556140 203 nlKLRKGMDLSEIINLSvNQNIVRTIMTS-STVFLSSLGLYLFGgnvLSDI-SFAF--LIGVVVGTLSSIFVASALV 275
Cdd:COG0342   350 --ELRAGRSLRAAIEAG-FKRAFSTILDAnVTTLIAAVVLFVLG---TGPVkGFAVtlILGILISMFTAVPVTRPLL 420
secD PRK08343
preprotein translocase subunit SecD; Reviewed
 17-116 1.78e-04

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 236245 [Multi-domain]  Cd Length: 417  Bit Score: 42.55  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  17 VISIILILLSAFSLY--------TRGLNLGLDFTGGTMLEVRFQTPVS------VKQV-DDALYKVNIKDAVVQRTNTGD 81
Cdd:PRK08343   14 LLLIVLVLASIVAIFppgggpggFTNLQYGLDLSGGSWIQLKLEGPVTqetmdlVVEIlESRLNALGLKDIKVYPVGDQY 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1327556140  82 IIVKIrVGEKPSLVEKALNSIGSFQ------------LLQREDIGSV 116
Cdd:PRK08343   94 IVVEV-PGVDADTAKEIIEKQGVFEariqtpgnnnetVLTGDDIESV 139
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 104-271 3.75e-04

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 41.76  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 104 SFQLLQREDIGSVVSGELRKKAVWAIITALVGILIYLSFRYEFLFALGGIlALAHDVFIVVGAYSWTYKEVSLDVLASIL 183
Cdd:PRK13024  247 PLKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYGLPGLIANI-ALLLYIFLTLGALSSLGAVLTLPGIAGLV 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 184 VVAGYSITDTVVVFDRIRENLKLRKGMDLSeiINLSvNQNIVRTIMTSS-TVFLSSLGLYLFG-GNVLsdiSFAF--LIG 259
Cdd:PRK13024  326 LGIGMAVDANVLIFERIKEELRKGKSLKKA--FKKG-FKNAFSTILDSNiTTLIAAAILFFFGtGPVK---GFATtlIIG 399

                         170
                  ....*....|..
gi 1327556140 260 VVVGTLSSIFVA 271
Cdd:PRK13024  400 ILASLFTAVFLT 411
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 123-271 5.94e-04

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 40.98  E-value: 5.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 123 KKAVWAIITALVGILIYLSFRYEfLFALGGILALAHDVFIVVGAYSWTykEVSLDvLASI--LVVA-GYSITDTVVVFDR 199
Cdd:PRK05812  297 RAGLIAGLIGLALVLLFMILYYR-LFGLIANIALVANLVLILAVLSLL--GATLT-LPGIagIVLTiGMAVDANVLIFER 372

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 200 IREnlKLRKGMdlseiinlSVNQNIV-------RTIMTSS-TVFLSSLGLYLFG-GNVLsdiSFAFLIGvvVGTLSSIFV 270
Cdd:PRK05812  373 IRE--ELREGR--------SLRSAIEagfkrafSTILDSNiTTLIAAIILYALGtGPVK---GFAVTLG--IGILTSMFT 437


                  .
gi 1327556140 271 A 271
Cdd:PRK05812  438 A 438
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 116-271 1.66e-03

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 39.84  E-value: 1.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  116 VVSGELRKKA-VWAIITALVGI---LIYLSFRYEFlfalGGILA---LAHDVFIVVGAYSWTYKEVSLDVLASILVVAGY 188
Cdd:PRK12911   898 VISPELGKSQrTQGIISVCLGLavlIVLMSVYYRF----GGVIAsgaVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGM 973

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140  189 SITDTVVVFDRIRENLKLRKgmDLSEIINLSVNQNIvRTIMTS--STVFLSSLGLYLFGGNVLsdisfAFLIGVVVGTLS 266
Cdd:PRK12911   974 AVDANVLVFERIREEYLLSR--SLSESVEAGYKKAF-SAIFDSnlTTILASALLLMLDTGPIK-----GFALTLIIGIFS 1045


                   ....*
gi 1327556140  267 SIFVA 271
Cdd:PRK12911  1046 SMFTA 1050
PRK13023 PRK13023
protein translocase subunit SecDF;
107-264 2.09e-03

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 39.60  E-value: 2.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 107 LLQREDIGSVVSGELRKKAVWAIITA--LVGILIYLSFRYEFLFALggiLALAHDVFIVVGAYSWTYKEVSLDVLASILV 184
Cdd:PRK13023  262 VLEERTIASALGEDYASAAVLAALLAalVVGLFMVLSYGILGVIAL---VALVVNIIILTAVLSLIGASISLASIAGLVL 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 185 VAGYSITDTVVVFDRIRENlkLRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSdiSFAFLIGVVVGT 264
Cdd:PRK13023  339 TIGLAVDAHILIYERVRED--RRKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVH--GFALTVAIGIGT 414
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 129-274 2.54e-03

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 39.44  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327556140 129 IITALVGILIYLSFRYEFLFALGGILALAHDVFIVV---GAYSWTYKEVSLDVLASILVVAGYSITDTVVVFDRIREnlK 205
Cdd:TIGR00921 197 TTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAwvlGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEE--E 274

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1327556140 206 LRKGMDLSEIINLSVNQNIVRTIMTSSTVFLSSLGLYLFGGNVLSDISFAFLIGVVVGTLSSIFVASAL 274
Cdd:TIGR00921 275 RDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPAL 343
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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