|
Name |
Accession |
Description |
Interval |
E-value |
| IolD |
COG3962 |
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism ... |
1-637 |
0e+00 |
|
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism [Carbohydrate transport and metabolism];
Pssm-ID: 443162 [Multi-domain] Cd Length: 622 Bit Score: 1102.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 1 MGKKIRLTTAQALIKFLNQQYIHVDGKEEPFVEGIFTIFGHGNVLGIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKQM 80
Cdd:COG3962 1 MMKTIRLTVAQALVRFLANQYVERDGEEQPLFAGVFGIFGHGNVAGLGQALEQDPDELPTYQGRNEQGMAHAAIAYAKQK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 81 LRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLIPADTFATRQPDPVLQQMEQEYSAAITTNDALKPVSRYWDRITRP 160
Cdd:COG3962 81 NRRRIMACTSSIGPGATNMVTAAALATANRLPVLLLPGDTFATRQPDPVLQQLEHFHDPTISVNDAFRPVSRYWDRITRP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 161 EQLMSSLLRAFEVMTDPAKAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGG 240
Cdd:COG3962 161 EQLMSALPRAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPPPDPAELARAVELIRAAKRPLIIAGGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 241 TKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDF 320
Cdd:COG3962 241 VRYSEATEALRAFAEATGIPVAETQAGKGALPWDHPLNLGGIGVTGTLAANALAAEADLVIGVGTRLQDFTTGSKTLFAN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 321 DKAKFLNINVSRMQAYKLDAFQVVADAKVTLGKLHGLLEG--YESEFGTTIRELKDEWLAERERLskvtfkreafdpeik 398
Cdd:COG3962 321 PDVRFVNINVARFDAYKHDALPVVADAREGLEALTEALAGwrYPAAWTDEAAELKAEWDAEVDRL--------------- 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 399 nhfsqevlneYADALNTELPQTTALLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGL 478
Cdd:COG3962 386 ----------YAPTNGGLPTQAQVIGAVNEAAGPDDIVVCAAGSLPGDLHKLWRTRDPGTYHVEYGYSCMGYEIAGGLGV 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 479 KLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRT-------DDNQILN 551
Cdd:COG3962 456 KLAEPDREVYVMVGDGSYLMLNSELVTSVQEGKKIIVVLLDNHGFGCINRLQMSTGSQSFGTELRDrdtetgrLDGGLLP 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 552 VDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLPKTMTDGYDSWWHVGVAEVSEQESVQKAYEAKEKKL 631
Cdd:COG3962 536 VDFAANAASLGAKAYRVTTIAELRAALERAKAADRTTVIVIKTDPKTMTPGGGSWWDVGVAEVSERESVRAARAEYEEAR 615
|
....*.
gi 1324265562 632 ESAKQY 637
Cdd:COG3962 616 AKQRRY 621
|
|
| myo_inos_iolD |
TIGR04377 |
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5 ... |
6-635 |
0e+00 |
|
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase (iolD), represent one of eight enzymes in a pathway converting myo-inositol to acetyl-CoA. IolD hydrolyzes the cyclic molecule 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione to yield 5-deoxy-D-glucuronic acid. TPP is a cofactor. [Energy metabolism, Sugars]
Pssm-ID: 275170 [Multi-domain] Cd Length: 615 Bit Score: 1007.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 6 RLTTAQALIKFLNQQYIHVDGKEEPFVEGIFTIFGHGNVLGIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKI 85
Cdd:TIGR04377 1 RLTMAQALVRFLAAQYVERDGEEVPFFAGVFAIFGHGNVAGLGEALEEDPDDLPTYRGRNEQGMAHAAIAYAKQKNRRRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 86 YAVSTSVGPGAANLVAAAGTALANNIPVLLIPADTFATRQPDPVLQQMEQEYSAAITTNDALKPVSRYWDRITRPEQLMS 165
Cdd:TIGR04377 81 MACTSSIGPGATNMVTAAALATVNRLPVLLLPGDTFATRQPDPVLQQLEDFSDLTVSVNDAFRPVSRYFDRITRPEQLMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 166 SLLRAFEVMTDPAKAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSG 245
Cdd:TIGR04377 161 ALPNAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPEPDPAELERAVAAIRAAKKPLIVAGGGVHYSE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 246 ARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFDKAKF 325
Cdd:TIGR04377 241 AGEALAAFAEKHGIPVAETQAGKGALPWDHPLNLGAIGVTGTLAANALAAEADLVIAVGTRLQDFTTASKTLFQNPDVRF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 326 LNINVSRMQAYKLDAFQVVADAKVTLGKLHGLLEGYE--SEFGTTIRELKDEWLAERERLSKVTFKreafdpeiknhfsq 403
Cdd:TIGR04377 321 VNINVARFDAYKHDALPLVADARAGLEALSEALGGYRadSAWAAEAAAAKAAWDAEVDRLYAAEYT-------------- 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 404 evlneyadalNTELP-QTTALLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAH 482
Cdd:TIGR04377 387 ----------AGGLPtQAEVIGAVNRAAGPDDVVVCAAGSLPGDLHKLWRTRDPGGYHMEYGYSCMGYEIAGGLGVKLAE 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 483 PDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRTDDNQ-----ILNVDYAKV 557
Cdd:TIGR04377 457 PDREVYVMVGDGSYLMLNSELATSVQEGKKIIVVLLDNRGFGCINNLQMSTGGASFNTELRYEDTGrldggLLPVDFAAH 536
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1324265562 558 AEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLPKTMTDGYDSWWHVGVAEVSEQESVQKAYEAKEKKLESAK 635
Cdd:TIGR04377 537 AAALGAKTYKVTTIAELEAALARAKAADRTTLIVIDTDPKTMTEGYGSWWDVGVAEVSERESVRKAREEYEEAKKAQR 614
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
419-616 |
1.34e-119 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 353.92 E-value: 1.34e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 419 QTTALLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLM 498
Cdd:cd02003 1 QTEVLGALNEAIGDDDVVINAAGSLPGDLHKLWRARTPGGYHLEYGYSCMGYEIAAGLGAKLAKPDREVYVLVGDGSYLM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 499 LHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRTDDN-------QILNVDYAKVAEGYGAKTYRANTV 571
Cdd:cd02003 81 LHSEIVTAVQEGLKIIIVLFDNHGFGCINNLQESTGSGSFGTEFRDRDQesgqldgALLPVDFAANARSLGARVEKVKTI 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1324265562 572 EELKAALEDAKKQDVSTLIEMKVLPKTMTDGYDSWWHVGVAEVSE 616
Cdd:cd02003 161 EELKAALAKAKASDRTTVIVIKTDPKSMTPGYGSWWDVGVAEVSE 205
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
6-596 |
5.73e-113 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 349.46 E-value: 5.73e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 6 RLTTAQALIKFLNQqyihvdgkeepfvEGIFTIFGH--GNVLGIGQALEQDAGhLKVYQGKNEQGMAHAAMAYSKqmLRR 83
Cdd:COG0028 2 KMTGADALVEALEA-------------EGVETVFGVpgGAILPLYDALRRQSG-IRHILVRHEQGAAFMADGYAR--ATG 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 84 KIYAVSTSVGPGAANLVAAAGTALANNIPVLLI----PADTFATRQpdpvLQQMEQeysAAITtndalKPVSRYWDRITR 159
Cdd:COG0028 66 KPGVCLVTSGPGATNLVTGLADAYMDSVPVLAItgqvPTSLIGRGA----FQEVDQ---VGLF-----RPITKWSYLVTD 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 160 PEQLMSSLLRAFEVMTDPaKAGPATICISQDVEGEAYDFdESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGG 239
Cdd:COG0028 134 PEDLPEVLRRAFRIATSG-RPGPVVLDIPKDVQAAEAEE-EPAPPELRGYRPRPAPDPEAIEEAAELLAAAKRPVILAGG 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 240 GTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFD 319
Cdd:COG0028 212 GARRAGAAEELRALAERLGAPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALAEADLVLAVGARFDDRVTGNWDEFA 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 320 fDKAKFLNINVSRMQ---AYKLDAFqVVADAKVTLGKLHGLLEGYE---SEFGTTIRELKDEWLAERERlskvtfKREAF 393
Cdd:COG0028 292 -PDAKIIHIDIDPAEigkNYPVDLP-IVGDAKAVLAALLEALEPRAddrAAWLARIAAWRAEYLAAYAA------DDGPI 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 394 DPeiknhfsQEVLNEyadalntelpqttalltINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVS 473
Cdd:COG0028 364 KP-------QRVIAA-----------------LREALPDDAIVVTDVGQHQMWAARYLRFRRPRRFLTSGGLGTMGYGLP 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 474 GTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYY-CEFRtddnqilNV 552
Cdd:COG0028 420 AAIGAKLARPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNNGGLGMVRQWQELFYGGRYSgTDLP-------NP 492
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1324265562 553 DYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLP 596
Cdd:COG0028 493 DFAKLAEAFGAKGERVETPEELEAALEEALASDGPALIDVRVDP 536
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
2-594 |
3.48e-56 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 199.62 E-value: 3.48e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 2 GKKIRLTTAQALIKFLNQqyihvdgkeepfvEGIFTIFGH--GNVLGIGQAL-EQDAGHLKVyqgKNEQGMAHAAMAYSK 78
Cdd:PRK06048 3 GSTEKMTGARAIIKCLEK-------------EGVEVIFGYpgGAIIPVYDELyDSDLRHILV---RHEQAAAHAADGYAR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 79 QMLRRKIyAVSTSvGPGAANLVAAAGTALANNIPVL---------LIPADTFatrqpdpvlqqmeQEysAAITtnDALKP 149
Cdd:PRK06048 67 ATGKVGV-CVATS-GPGATNLVTGIATAYMDSVPIValtgqvprsMIGNDAF-------------QE--ADIT--GITMP 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 150 VSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKS 229
Cdd:PRK06048 128 ITKHNYLVQDAKDLPRIIKEAFHIAST-GRPGPVLIDLPKDVTTAEIDFDYPDKVELRGYKPTYKGNPQQIKRAAELIMK 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 230 SKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTD 309
Cdd:PRK06048 207 AERPIIYAGGGVISSNASEELVELAETIPAPVTTTLMGIGAIPTEHPLSLGMLGMHGTKYANYAIQESDLIIAVGARFDD 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 310 FATSSKTAFDfDKAKFLNINVSRMQAYKLDAFQV--VADAKVTLGKLHGLLEgyesefgttiRELKDEWlaererLSKVt 387
Cdd:PRK06048 287 RVTGKLASFA-PNAKIIHIDIDPAEISKNVKVDVpiVGDAKQVLKSLIKYVQ----------YCDRKEW------LDKI- 348
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 388 fkreafdpeikNHFSQEVLNEYADALNTELPQTTaLLTINETIPeDSVIICSAGSlpgdlQRLWHSNV-----PNTYHLE 462
Cdd:PRK06048 349 -----------NQWKKEYPLKYKEREDVIKPQYV-IEQIYELCP-DAIIVTEVGQ-----HQMWAAQYfkykyPRTFITS 410
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 463 YGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEF 542
Cdd:PRK06048 411 GGLGTMGYGFPAAIGAKVGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNGYLGMVRQWQELFYDKRYSHTC 490
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 1324265562 543 RTDdnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK06048 491 IKG-----SVDFVKLAEAYGALGLRVEKPSEVRPAIEEAVASDRPVVIDFIV 537
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
33-601 |
4.92e-56 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 198.70 E-value: 4.92e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFG--HGNVLGIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIYAVSTsvGPGAANLVAAAGTALANN 110
Cdd:PRK08266 17 HGVDTVFGlpGAQLYWLFDALYKAGDRIRVIHTRHEQAAGYMAFGYARSTGRPGVCSVVP--GPGVLNAGAALLTAYGCN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 111 IPVLL----IPADTFAtrQPDPVLQQMEQEYSAaittndaLKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATIC 186
Cdd:PRK08266 95 SPVLCltgqIPSALIG--KGRGHLHEMPDQLAT-------LRSFTKWAERIEHPSEAPALVAEAFQQMLS-GRPRPVALE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 187 ISQDVEGEAYDFDEsffVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTkySGARDELVAISEAYNIPLVETQA 266
Cdd:PRK08266 165 MPWDVFGQRAPVAA---APPLRPAPPPAPDPDAIAAAAALIAAAKNPMIFVGGGA--AGAGEEIRELAEMLQAPVVAFRS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 267 GKSTVEADFANNLGgmgitgTLAANKAARQADLIIGIGTRYTDfaTSSKTAFDFDKAKFLNINV--SRMQAYKLDAfQVV 344
Cdd:PRK08266 240 GRGIVSDRHPLGLN------FAAAYELWPQTDVVIGIGSRLEL--PTFRWPWRPDGLKVIRIDIdpTEMRRLKPDV-AIV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 345 ADAKvtlgklHGLlegyesefgttiRELKDewlAERERLSKVTFKREAFdpeiknhfsqEVLNEYADALNTEL-PQTTAL 423
Cdd:PRK08266 311 ADAK------AGT------------AALLD---ALSKAGSKRPSRRAEL----------RELKAAARQRIQAVqPQASYL 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 424 LTINETIPEDSVI---ICSAGslpgdlqrlWHSNV------PNTYhLEYGYS-CMGYEVSGTLGLKLAHPDREVYSIVGD 493
Cdd:PRK08266 360 RAIREALPDDGIFvdeLSQVG---------FASWFafpvyaPRTF-VTCGYQgTLGYGFPTALGAKVANPDRPVVSITGD 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 494 GSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYyceFRTDdnqILNVDYAKVAEGYGAKTYRANTVEE 573
Cdd:PRK08266 430 GGFMFGVQELATAVQHNIGVVTVVFNNNAYGNVRRDQKRRFGGRV---VASD---LVNPDFVKLAESFGVAAFRVDSPEE 503
|
570 580
....*....|....*....|....*...
gi 1324265562 574 LKAALEDAKKQDVSTLIEMKVLPKTMTD 601
Cdd:PRK08266 504 LRAALEAALAHGGPVLIEVPVPRGSEAS 531
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
33-594 |
7.96e-56 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 198.78 E-value: 7.96e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGI-GQALEQDagHLKVYQGKNEQGMAHAAMAYSKQMLRRKIyAVSTSvGPGAANLVAAAGTALAN 109
Cdd:PRK08527 16 EGVKVVFGYpgGAILNIyDEIYKQN--YFKHILTRHEQAAVHAADGYARASGKVGV-AIVTS-GPGFTNAVTGLATAYMD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 110 NIPVLLIPAdtfatrqpdpvlqqmeQEYSAAITTnDALKPVSRYwdRITRP-----------EQLMSSLLRAFEVMTDpA 178
Cdd:PRK08527 92 SIPLVLISG----------------QVPNSLIGT-DAFQEIDAV--GISRPcvkhnylvksiEELPRILKEAFYIARS-G 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 179 KAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYN 258
Cdd:PRK08527 152 RPGPVHIDIPKDVTATLGEFEYPKEISLKTYKPTYKGNSRQIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 259 IPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDfDKAKFLNINVSRMQAYKL 338
Cdd:PRK08527 232 IPAVETLMARGVLRSDDPLLLGMLGMHGSYAANMAMSECDLLISLGARFDDRVTGKLSEFA-KHAKIIHVDIDPSSISKI 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 339 DA--FQVVADAKVTLGKLHGLLEGYESEFGTTIRELkdewLAERERLSKVTFKReafdpeiknhfSQEVLNeyadalnte 416
Cdd:PRK08527 311 VNadYPIVGDLKNVLKEMLEELKEENPTTYKEWREI----LKRYNELHPLSYED-----------SDEVLK--------- 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 417 lPQtTALLTINETIPEDSVIICSAGSlpgdlQRLWHS-----NVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIV 491
Cdd:PRK08527 367 -PQ-WVIERVGELLGDDAIISTDVGQ-----HQMWVAqfypfNYPRQLATSGGLGTMGYGLPAALGAKLAVPDKVVINFT 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 492 GDGSFLMLHSELITAIQYNKK-INVLLfDNSGFGCINNLQMdhgsgSYYCEFRTDDNQILNVDYAKVAEGYGAKTYRANT 570
Cdd:PRK08527 440 GDGSILMNIQELMTAVEYKIPvINIIL-NNNFLGMVRQWQT-----FFYEERYSETDLSTQPDFVKLAESFGGIGFRVTT 513
|
570 580
....*....|....*....|....
gi 1324265562 571 VEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK08527 514 KEEFDKALKEALESDKVALIDVKI 537
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
7-596 |
1.31e-55 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 198.82 E-value: 1.31e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 7 LTTAQALIKFLNQqyihvdgkeepfvEGIFTIFGH--GNVLGIGQAL-EQDAGHLKVyqgKNEQGMAHAAMAYSKQMLRR 83
Cdd:PRK06276 1 MKGAEAIIKALEA-------------EGVKIIFGYpgGALLPFYDALyDSDLIHILT---RHEQAAAHAADGYARASGKV 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 84 KIyAVSTSvGPGAANLVAAAGTALANNIPVL---------LIPADTFatrqpdpvlqqmeQEYSA-AITTndalkPVSRY 153
Cdd:PRK06276 65 GV-CVATS-GPGATNLVTGIATAYADSSPVIaltgqvptkLIGNDAF-------------QEIDAlGIFM-----PITKH 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 154 WDRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVEGEAYDFDESFFVKRVH---YIDRMQPSERELQGAAELIKSS 230
Cdd:PRK06276 125 NFQIKKPEEIPEIFRAAFEIAKT-GRPGPVHIDLPKDVQEGELDLEKYPIPAKIDlpgYKPTTFGHPLQIKKAAELIAEA 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 231 KKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDF 310
Cdd:PRK06276 204 ERPVILAGGGVIISGASEELIELSELVKIPVCTTLMGKGAFPEDHPLALGMVGMHGTKAANYSVTESDVLIAIGCRFSDR 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 311 ATSSKTAFDFDkAKFLNINVSRMQAYKLDAFQV--VADAKVTLGKLHGLLEGYESefgttirELKDEWLAERERLSKVTF 388
Cdd:PRK06276 284 TTGDISSFAPN-AKIIHIDIDPAEIGKNVRVDVpiVGDAKNVLRDLLAELMKKEI-------KNKSEWLERVKKLKKESI 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 389 KREAFDPE-IKnhfSQEVLNEYADALNTELPQTtalltinetipeDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSC 467
Cdd:PRK06276 356 PRMDFDDKpIK---PQRVIKELMEVLREIDPSK------------NTIITTDVGQNQMWMAHFFKTSAPRSFISSGGLGT 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 468 MGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHgSGSYYCEFRTDDN 547
Cdd:PRK06276 421 MGFGFPAAIGAKVAKPDANVIAITGDGGFLMNSQELATIAEYDIPVVICIFDNRTLGMVYQWQNLY-YGKRQSEVHLGET 499
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1324265562 548 QilnvDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLP 596
Cdd:PRK06276 500 P----DFVKLAESYGVKADRVEKPDEIKEALKEAIKSGEPYLLDIIIDP 544
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
22-594 |
8.40e-54 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 193.52 E-value: 8.40e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 22 IHVDGKEEPFVEGIFTIFGHGNvLGIGQALEQD--AGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIyaVSTSVGPGAANL 99
Cdd:PRK06456 7 ILVDSLKREGVKVIFGIPGLSN-MQIYDAFVEDlaNGELRHVLMRHEQAAAHAADGYARASGVPGV--CTATSGPGTTNL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 100 VAAAGTALANNIPVLLIPADTfatrqPDPVLQQMEQEYSAAITTndaLKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAK 179
Cdd:PRK06456 84 VTGLITAYWDSSPVIAITGQV-----PRSVMGKMAFQEADAMGV---FENVTKYVIGIKRIDEIPQWIKNAFYIATT-GR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 180 AGPATICISQDVEGEAYD---FDESFFVKRVH----YIDRMqpserELQGAAELIKSSKKPVILVGGGTKYSGARDELVA 252
Cdd:PRK06456 155 PGPVVIDIPRDIFYEKMEeikWPEKPLVKGYRdfptRIDRL-----ALKKAAEILINAERPIILVGTGVVWSNATPEVLE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 253 ISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFDKAKFLNINVSR 332
Cdd:PRK06456 230 LAELLHIPIVSTFPGKTAIPHDHPLYFGPMGYYGRAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDP 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 333 ---MQAYKLDAfQVVADAKVTLgklhgllegyeSEFGTTIREL-----KDEWLaererlskvtfKREAfdpEIKNHFSQE 404
Cdd:PRK06456 310 tdgEKAIKVDV-GIYGNAKIIL-----------RELIKAITELgqkrdRSAWL-----------KRVK---EYKEYYSQF 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 405 vlneYADALNTELPQTTALLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPD 484
Cdd:PRK06456 364 ----YYTEENGKLKPWKIMKTIRQALPRDAIVTTGVGQHQMWAEVFWEVLEPRTFLTSSGMGTMGFGLPAAMGAKLARPD 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 485 REVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQmDHGSGsyycefrtddNQILNVDYA------KVA 558
Cdd:PRK06456 440 KVVVDLDGDGSFLMTGTNLATAVDEHIPVISVIFDNRTLGLVRQVQ-DLFFG----------KRIVGVDYGpspdfvKLA 508
|
570 580 590
....*....|....*....|....*....|....*.
gi 1324265562 559 EGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK06456 509 EAFGALGFNVTTYEDIEKSLKSAIKEDIPAVIRVPV 544
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
52-596 |
8.20e-53 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 190.60 E-value: 8.20e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 52 EQDAghLKVYQGKNEQGMAHAAMAYSKqmLRRKIyAVSTSV-GPGAANLVAAAGTALANNIPVLLIPADTFATrqpdpvl 130
Cdd:PRK08611 40 EQDK--IKFIQVRHEEVAALAAAAYAK--LTGKI-GVCLSIgGPGAIHLLNGLYDAKMDHVPVLALAGQVTSD------- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 131 qQMEQEYSAAITTNDALKPVSRYWDRITRPEQLMSSLLRAfeVMTDPAKAGPATICISQDV----EGEAYDFDESFFVKR 206
Cdd:PRK08611 108 -LLGTDFFQEVNLEKMFEDVAVYNHQIMSAENLPEIVNQA--IRTAYEKKGVAVLTIPDDLpaqkIKDTTNKTVDTFRPT 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 207 VhyidrMQPSERELQGAAELIKSSKKPVILVGGGTKysGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITG 286
Cdd:PRK08611 185 V-----PSPKPKDIKKAAKLINKAKKPVILAGLGAK--HAKEELLAFAEKAKIPIIHTLPAKGIIPDDHPYSLGNLGKIG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 287 TLAANKAARQADLIIGIGTR--YTDFATssktafdfDKAKFLNINVSRMQA---YKLDAfQVVADAKVTlgkLHGLLEgy 361
Cdd:PRK08611 258 TKPAYEAMQEADLLIMVGTNypYVDYLP--------KKAKAIQIDTDPANIgkrYPVNV-GLVGDAKKA---LHQLTE-- 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 362 esefgttirelKDEWLAERERLSKVTFKREAFDPEIKNhfsqevlneyaDALNTELP----QTTAllTINETIPEDSVII 437
Cdd:PRK08611 324 -----------NIKHVEDRRFLEACQENMAKWWKWMEE-----------DENNASTPikpeRVMA--AIQKIADDDAVLS 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 438 CSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLL 517
Cdd:PRK08611 380 VDVGTVTVWSARYLNLGTNQKFIISSWLGTMGCGLPGAIAAKIAFPDRQAIAICGDGGFSMVMQDFVTAVKYKLPIVVVV 459
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1324265562 518 FDNSGFGCINNLQMDHGSGSYYCEFRtddnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLP 596
Cdd:PRK08611 460 LNNQQLAFIKYEQQAAGELEYAIDLS-------DMDYAKFAEACGGKGYRVEKAEELDPAFEEALAQDKPVIIDVYVDP 531
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
66-594 |
1.12e-52 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 189.65 E-value: 1.12e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 66 EQGMAHAAMAYSKqmLRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLIpadtfaTRQ-PdpvLQQMEQEYSAAITTN 144
Cdd:PRK08322 47 EQGAAFMAATYGR--LTGKAGVCLSTLGPGATNLVTGVAYAQLGGMPMVAI------TGQkP---IKRSKQGSFQIVDVV 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 145 DALKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVEGEAYDFDesffVKRVHYIDRMQPSERELQGAA 224
Cdd:PRK08322 116 AMMAPLTKWTRQIVSPDNIPEVVREAFRLAEE-ERPGAVHLELPEDIAAEETDGK----PLPRSYSRRPYASPKAIERAA 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 225 ELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIG 304
Cdd:PRK08322 191 EAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIPFFTTQMGKGVIPETHPLSLGTAGLSQGDYVHCAIEHADLIINVG 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 305 TRYTDFAtssktafdfdkAKFLN-------INVSRMQA-----YKLDAfQVVADakvtlgklhgllegyeseFGTTIREL 372
Cdd:PRK08322 271 HDVIEKP-----------PFFMNpngdkkvIHINFLPAevdpvYFPQV-EVVGD------------------IANSLWQL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 373 KdewlaerERLSKVTFKREAFDPEIKNHFSQEvLNEYADAlnTELPQTTALL--TINETIPEDSVIICSAGSLPGDLQRL 450
Cdd:PRK08322 321 K-------ERLADQPHWDFPRFLKIREAIEAH-LEEGADD--DRFPMKPQRIvaDLRKVMPDDDIVILDNGAYKIWFARN 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 451 WHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQ 530
Cdd:PRK08322 391 YRAYEPNTCLLDNALATMGAGLPSAIAAKLVHPDRKVLAVCGDGGFMMNSQELETAVRLGLPLVVLILNDNAYGMIRWKQ 470
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1324265562 531 MDHGSGSYYCEFRtddnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK08322 471 ENMGFEDFGLDFG-------NPDFVKYAESYGAKGYRVESADDLLPTLEEALAQPGVHVIDCPV 527
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
440-591 |
9.77e-51 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 172.38 E-value: 9.77e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 440 AGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFD 519
Cdd:pfam02775 2 IGCHQMWAAQYYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVLN 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1324265562 520 NSGFGCINNLQMDHGSGSYYCefrTDDNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIE 591
Cdd:pfam02775 82 NGGYGMTRGQQTPFGGGRYSG---PSGKILPPVDFAKLAEAYGAKGARVESPEELEEALKEALEHDGPALID 150
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
34-594 |
6.30e-49 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 179.63 E-value: 6.30e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 34 GIFTIFGH--GNVLGIGQALEQDAGhLKVYQGKNEQGMAHAAMAYSKQMLRRKIyAVSTSvGPGAANLVAAAGTALANNI 111
Cdd:PRK07282 24 GVDTIFGYpgGAVLPLYDAIYNFEG-IRHILARHEQGALHEAEGYAKSTGKLGV-AVVTS-GPGATNAITGIADAMSDSV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 112 PVLL---------IPADTFatRQPDPVlqqmeqeysaAITTndalkPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGP 182
Cdd:PRK07282 101 PLLVftgqvaragIGKDAF--QEADIV----------GITM-----PITKYNYQIRETADIPRIITEAVHIATT-GRPGP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 183 ATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLV 262
Cdd:PRK07282 163 VVIDLPKDVSALETDFIYDPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 263 ETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDfDKAKFLNINVSRMQAYKL--DA 340
Cdd:PRK07282 243 TTLLGQGTIATSHPLFLGMGGMHGSYAANIAMTEADFMINIGSRFDDRLTGNPKTFA-KNAKVAHIDIDPAEIGKIikTD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 341 FQVVADAKVTLGKLHGLlegyesefgTTIRELKDEWLaerERLSKVTFKREAFDPeiKNHFSQevlneyadalntelPQt 420
Cdd:PRK07282 322 IPVVGDAKKALQMLLAE---------PTVHNNTEKWI---EKVTKDKNRVRSYDK--KERVVQ--------------PQ- 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 421 TALLTINETIPEDSVIICSAGSlpgdlQRLWHSNV---PNTYHL--EYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGS 495
Cdd:PRK07282 373 AVIERIGELTNGDAIVVTDVGQ-----HQMWAAQYypyQNERQLvtSGGLGTMGFGIPAAIGAKIANPDKEVILFVGDGG 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 496 FLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMdhgsgSYYCEFRTDDNQILNVDYAKVAEGYGAKTYRANTVEELK 575
Cdd:PRK07282 448 FQMTNQELAILNIYKVPIKVVMLNNHSLGMVRQWQE-----SFYEGRTSESVFDTLPDFQLMAQAYGIKHYKFDNPETLA 522
|
570
....*....|....*....
gi 1324265562 576 AALEdAKKQDVSTLIEMKV 594
Cdd:PRK07282 523 QDLE-VITEDVPMLIEVDI 540
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
33-581 |
1.28e-44 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 167.84 E-value: 1.28e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQALEQDAghLKVYQGKNEQGMAHAAMAYSKqmLRRKIYAVSTSVGPGAANLVAAAGTALANN 110
Cdd:PRK06725 28 LGVTTVFGYpgGAILPVYDALYESG--LKHILTRHEQAAIHAAEGYAR--ASGKVGVVFATSGPGATNLVTGLADAYMDS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 111 IPVLLIPADTFATRQPDPVLQQMEqeySAAITTndalkPVSRYWDRITRPEQLMSSLLRAFEVmTDPAKAGPATICISQD 190
Cdd:PRK06725 104 IPLVVITGQVATPLIGKDGFQEAD---VVGITV-----PVTKHNYQVRDVNQLSRIVQEAFYI-AESGRPGPVLIDIPKD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 191 VEGE--AYDFDESFFVKrvHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGK 268
Cdd:PRK06725 175 VQNEkvTSFYNEVVEIP--GYKPEPRPDSMKLREVAKAISKAKRPLLYIGGGVIHSGGSEELIEFARENRIPVVSTLMGL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 269 STVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFAT---------SSKTAFDFDKAKF-LNINVSrmqaykl 338
Cdd:PRK06725 253 GAYPPGDPLFLGMLGMHGTYAANMAVTECDLLLALGVRFDDRVTgklelfsphSKKVHIDIDPSEFhKNVAVE------- 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 339 daFQVVADAKVTLGK-LHGLLEGYESEFGTTIRELKDEWlaererlsKVTFKREafDPEIKnhfSQEVLNEYADALNTEL 417
Cdd:PRK06725 326 --YPVVGDVKKALHMlLHMSIHTQTDEWLQKVKTWKEEY--------PLSYKQK--ESELK---PQHVINLVSELTNGEA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 418 PQTTALltinetipedsviicsagslpGDLQrLWHSNV-----PNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVG 492
Cdd:PRK06725 391 IVTTEV---------------------GQHQ-MWAAHFykaknPRTFLTSGGLGTMGFGFPAAIGAQLAKEEELVICIAG 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 493 DGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQmdhgsgSYYCEFRTDDNQILNVDYAKVAEGYGAKTYRANTVE 572
Cdd:PRK06725 449 DASFQMNIQELQTIAENNIPVKVFIINNKFLGMVRQWQ------EMFYENRLSESKIGSPDFVKVAEAYGVKGLRATNST 522
|
....*....
gi 1324265562 573 ELKAALEDA 581
Cdd:PRK06725 523 EAKQVMLEA 531
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
64-591 |
3.31e-43 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 163.44 E-value: 3.31e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 64 KNEQGMAHAAMAYSKQMLRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLIPADTfatrqPDPvLQQMEQEYSAAItt 143
Cdd:PRK06154 61 RTERVAVHMADGYARATSGERVGVFAVQYGPGAENAFGGVAQAYGDSVPVLFLPTGY-----PRG-STDVAPNFESLR-- 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 144 ndALKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVEGEayDFDESFFVKRVHYIDRMQPSERELQGA 223
Cdd:PRK06154 133 --NYRHITKWCEQVTLPDEVPELMRRAFTRLRN-GRPGPVVLELPVDVLAE--ELDELPLDHRPSRRSRPGADPVEVVEA 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 224 AELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLG--GMGITGTLAanKAARQADLII 301
Cdd:PRK06154 208 AALLLAAERPVIYAGQGVLYAQATPELKELAELLEIPVMTTLNGKSAFPEDHPLALGsgGRARPATVA--HFLREADVLF 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 302 GIGTRYTDFA-----TSSKTAFD--FDKAKfLNINVSRMQAykldafqVVADAKVTLGKL-------HGLLEGYESEFGT 367
Cdd:PRK06154 286 GIGCSLTRSYyglpmPEGKTIIHstLDDAD-LNKDYPIDHG-------LVGDAALVLKQMieelrrrVGPDRGRAQQVAA 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 368 TIRELKDEWLAERErlSKVTfkreafdpeiknhfSQEV-LNEYAdaLNTELPQTTAlltinetiPEDSVIICSAGSLPGD 446
Cdd:PRK06154 358 EIEAVRAAWLAKWM--PKLT--------------SDSTpINPYR--VVWELQHAVD--------IKTVIITHDAGSPRDQ 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 447 LQRLWHSNVPNTYhLEYGYSC-MGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGc 525
Cdd:PRK06154 412 LSPFYVASRPGSY-LGWGKTTqLGYGLGLAMGAKLARPDALVINLWGDAAFGMTGMDFETAVRERIPILTILLNNFSMG- 489
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1324265562 526 INNLQMDHGSGSYycefRTDDnqiLNVDYAKVAEGYGAKTYRANTVEELKAALE---DAKKQDVSTLIE 591
Cdd:PRK06154 490 GYDKVMPVSTTKY----RATD---ISGDYAAIARALGGYGERVEDPEMLVPALLralRKVKEGTPALLE 551
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
33-581 |
3.08e-42 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 160.76 E-value: 3.08e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQALEQDAG--HLKVyqgKNEQGMAHAAMAYSKQMlrRKIYAVSTSVGPGAANLVAAAGTALA 108
Cdd:PRK08979 17 EGVKHIFGYpgGSVLDIYDALHEKSGieHILV---RHEQAAVHMADGYARAT--GKVGVVLVTSGPGATNTITGIATAYM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 109 NNIPVLLIPADTfatrqpdpvlqqmeqeySAAITTNDAL---------KPVSRYWDRITRPEQLMSSLLRAFEVMTDpAK 179
Cdd:PRK08979 92 DSIPMVVLSGQV-----------------PSNLIGNDAFqecdmigisRPVVKHSFLVKDAEDIPEIIKKAFYIAST-GR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 180 AGPATICISQDVEGEA----YDFDESffVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISE 255
Cdd:PRK08979 154 PGPVVIDLPKDCLNPAilhpYEYPES--IKMRSYNPTTSGHKGQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 256 AYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDfatssKTAFDFDK----AKFLNINV- 330
Cdd:PRK08979 232 KLNLPVVSTLMGLGAFPGTHKNSLGMLGMHGRYEANMAMHNADLIFGIGVRFDD-----RTTNNLEKycpnATILHIDId 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 331 --SRMQAYKLDaFQVVADAKVTLGKLHGLLEGYEsefGTTIRELKDEWLAE----RERlskvtfKREAFDPEIKNHFSQE 404
Cdd:PRK08979 307 psSISKTVRVD-IPIVGSADKVLDSMLALLDESG---ETNDEAAIASWWNEievwRSR------NCLAYDKSSERIKPQQ 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 405 VLneyadalntelpQTTALLTINETIPEDSV---IICSAGSLPGDLQRLWHSNvpntyhleYGYSCMGYEVSGTLGLKLA 481
Cdd:PRK08979 377 VI------------ETLYKLTNGDAYVASDVgqhQMFAALYYPFDKPRRWINS--------GGLGTMGFGLPAAMGVKFA 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 482 HPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGsyycefRTDDNQILNV-DYAKVAEG 560
Cdd:PRK08979 437 MPDETVVCVTGDGSIQMNIQELSTALQYDIPVKIINLNNRFLGMVKQWQDMIYQG------RHSHSYMDSVpDFAKIAEA 510
|
570 580
....*....|....*....|.
gi 1324265562 561 YGAKTYRANTVEELKAALEDA 581
Cdd:PRK08979 511 YGHVGIRISDPDELESGLEKA 531
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
6-594 |
5.67e-42 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 160.99 E-value: 5.67e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 6 RLTTAQALIKFLNQQyihvdgkeepfveGIFTIFGH--GNVLGIGQAL---EQDaGHLKVYQGKNEQGMAHAAMAYSKQM 80
Cdd:PRK07418 18 RATGAYALMDSLKRH-------------GVKHIFGYpgGAILPIYDELykaEAE-GWLKHILVRHEQGAAHAADGYARAT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 81 LRRKIyAVSTSvGPGAANLVAAAGTALANNIPVLLIpadtfaTRQ-PDPvlqqmeqeysaAITTnDALK---------PV 150
Cdd:PRK07418 84 GKVGV-CFGTS-GPGATNLVTGIATAQMDSVPMVVI------TGQvPRP-----------AIGT-DAFQetdifgitlPI 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 151 SRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVEGEAYDFD--ESFFVKRVHYIDRMQPSERELQGAAELIK 228
Cdd:PRK07418 144 VKHSYVVRDPSDMARIVAEAFHIASS-GRPGPVLIDIPKDVGQEEFDYVpvEPGSVKPPGYRPTVKGNPRQINAALKLIE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 229 SSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYT 308
Cdd:PRK07418 223 EAERPLLYVGGGAISAGAHAELKELAERFQIPVTTTLMGKGAFDEHHPLSVGMLGMHGTAYANFAVTECDLLIAVGARFD 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 309 D--------FATSSKTA-FDFDKAKflnINVSRmqaykLDAFQVVADAKVTLGKLHGLLEGYESEFGTTirelkdEWLAE 379
Cdd:PRK07418 303 DrvtgkldeFASRAKVIhIDIDPAE---VGKNR-----RPDVPIVGDVRKVLVKLLERSLEPTTPPRTQ------AWLER 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 380 RERLskvtfkreafdpeiKNHFSQEVlNEYADALNtelPQTTaLLTINETIPeDSVIICSAGSlpgdlQRLWHS----NV 455
Cdd:PRK07418 369 INRW--------------KQDYPLVV-PPYEGEIY---PQEV-LLAVRDLAP-DAYYTTDVGQ-----HQMWAAqflrNG 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 456 PNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMdhgs 535
Cdd:PRK07418 424 PRRWISSAGLGTMGFGMPAAMGVKVALPDEEVICIAGDASFLMNIQELGTLAQYGINVKTVIINNGWQGMVRQWQE---- 499
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1324265562 536 gSYYCEfRTDDNQILN--VDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK07418 500 -SFYGE-RYSASNMEPgmPDFVKLAEAFGVKGMVISERDQLKDAIAEALAHDGPVLIDVHV 558
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
220-354 |
5.10e-41 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 145.78 E-value: 5.10e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 220 LQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADL 299
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALEEADL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1324265562 300 IIGIGTRYTDFATSSKTAFDFDKAKFLNINVSRMQAYKLDA--FQVVADAKVTLGKL 354
Cdd:pfam00205 81 VLAVGARFDDIRTTGKLPEFAPDAKIIHIDIDPAEIGKNYPvdVPIVGDAKETLEAL 137
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
6-581 |
2.26e-40 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 156.29 E-value: 2.26e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 6 RLTTAQALIKFLnqqyihvdgkEEPFVEGIFTIFGhGNVLGIGQALEQDAG--HLKVyqgKNEQGMAHAAMAYSkQMLRR 83
Cdd:PRK07789 30 RMTGAQAVVRSL----------EELGVDVVFGIPG-GAILPVYDPLFDSTKvrHVLV---RHEQGAGHAAEGYA-QATGR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 84 KIYAVSTSvGPGAANLVAAAGTALANNIPVLLIPAdtfatrqpdpvlqqmeQEYSAAITTnDALK---------PVSRYW 154
Cdd:PRK07789 95 VGVCMATS-GPGATNLVTPIADANMDSVPVVAITG----------------QVGRGLIGT-DAFQeadivgitmPITKHN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 155 DRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPV 234
Cdd:PRK07789 157 FLVTDADDIPRVIAEAFHIAST-GRPGPVLVDIPKDALQAQTTFSWPPRMDLPGYRPVTKPHGKQIREAAKLIAAARRPV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 235 ILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSS 314
Cdd:PRK07789 236 LYVGGGVIRAEASAELRELAELTGIPVVTTLMARGAFPDSHPQHLGMPGMHGTVAAVAALQRSDLLIALGARFDDRVTGK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 315 KTAFDFDkAKFLNINVSRMQAYKLDAFQV--VADAKVTLGKlhgLLEGYESEFGTTIRELKDEWLAERERLSKvTFKReA 392
Cdd:PRK07789 316 LDSFAPD-AKVIHADIDPAEIGKNRHADVpiVGDVKEVIAE---LIAALRAEHAAGGKPDLTAWWAYLDGWRE-TYPL-G 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 393 FDPEIKNHFS-QEVLNeyadalntelpqttallTINETIPEDSVIICSAGSlpgdlQRLWHSNV-----PNTYHLEYGYS 466
Cdd:PRK07789 390 YDEPSDGSLApQYVIE-----------------RLGEIAGPDAIYVAGVGQ-----HQMWAAQFidyekPRTWLNSGGLG 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 467 CMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSY-YCEFRTD 545
Cdd:PRK07789 448 TMGYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQELATCAIEGIPIKVALINNGNLGMVRQWQTLFYEERYsNTDLHTH 527
|
570 580 590
....*....|....*....|....*....|....*.
gi 1324265562 546 DNQIlnVDYAKVAEGYGAKTYRANTVEELKAALEDA 581
Cdd:PRK07789 528 SHRI--PDFVKLAEAYGCVGLRCEREEDVDAVIEKA 561
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
425-594 |
2.26e-40 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 145.09 E-value: 2.26e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 425 TINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELI 504
Cdd:cd00568 5 ALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRPVVCIAGDGGFMMTGQELA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 505 TAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCefrtddNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQ 584
Cdd:cd00568 85 TAVRYGLPVIVVVFNNGGYGTIRMHQEAFYGGRVSG------TDLSNPDFAALAEAYGAKGVRVEDPEDLEAALAEALAA 158
|
170
....*....|
gi 1324265562 585 DVSTLIEMKV 594
Cdd:cd00568 159 GGPALIEVKT 168
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
34-596 |
5.06e-40 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 154.86 E-value: 5.06e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 34 GIFTIFGH--GNVLGIGQALE--QDAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKI-YAVStsvGPGAANLVAAAGTALA 108
Cdd:CHL00099 24 GVKHIFGYpgGAILPIYDELYawEKKGLIKHILVRHEQGAAHAADGYARSTGKVGVcFATS---GPGATNLVTGIATAQM 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 109 NNIPVLLIPAdtfatrqpdpvlqqmeQEYSAAITTnDALKPVSRYwdRITRP----------EQLMSSLLRAFEVMTDPA 178
Cdd:CHL00099 101 DSVPLLVITG----------------QVGRAFIGT-DAFQEVDIF--GITLPivkhsyvvrdARDISRIVAEAFYIAKHG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 179 KAGPATICISQDVEGEAYDFDESFFVKRVHYI----DRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAIS 254
Cdd:CHL00099 162 RPGPVLIDIPKDVGLEKFDYYPPEPGNTIIKIlgcrPIYKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 255 EAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFdKAKFLNINVSRMQ 334
Cdd:CHL00099 242 ELYKIPVTTTLMGKGIFDEDHPLCLGMLGMHGTAYANFAVSECDLLIALGARFDDRVTGKLDEFAC-NAQVIHIDIDPAE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 335 AYKLDAFQV--VADAKVTLGKLHGLLEGYESEFGttirelKDEWLAERERLSKVtfkREAFD---PEIKNHFS-QEVLNE 408
Cdd:CHL00099 321 IGKNRIPQVaiVGDVKKVLQELLELLKNSPNLLE------SEQTQAWRERINRW---RKEYPlliPKPSTSLSpQEVINE 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 409 yadaLNTELPQttALLTIN---ETIPEDSVIICSagslpgdlQRLWHSNVpntyhleyGYSCMGYEVSGTLGLKLAHPDR 485
Cdd:CHL00099 392 ----ISQLAPD--AYFTTDvgqHQMWAAQFLKCK--------PRKWLSSA--------GLGTMGYGLPAAIGAQIAHPNE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 486 EVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMdhgsgSYYCEFRTDDNQILNV-DYAKVAEGYGAK 564
Cdd:CHL00099 450 LVICISGDASFQMNLQELGTIAQYNLPIKIIIINNKWQGMVRQWQQ-----AFYGERYSHSNMEEGApDFVKLAEAYGIK 524
|
570 580 590
....*....|....*....|....*....|..
gi 1324265562 565 TYRANTVEELKAALEDAKKQDVSTLIEMKVLP 596
Cdd:CHL00099 525 GLRIKSRKDLKSSLKEALDYDGPVLIDCQVIE 556
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
10-579 |
6.80e-39 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 150.80 E-value: 6.80e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 10 AQALIKFLNQQyihvdgkeepfveGIFTIFGH--GNVLGIGQALeQDAG--HLKVyqgKNEQGMAHAAMAYSKQMLRRKI 85
Cdd:PRK08978 4 AQWVVHALRAQ-------------GVDTVFGYpgGAIMPVYDAL-YDGGveHLLC---RHEQGAAMAAIGYARATGKVGV 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 86 yAVSTSvGPGAANLVAAAGTALANNIPVL---------LIPADTFatrqpdpvlqqmeQE-----YSAAITTNDALkpvs 151
Cdd:PRK08978 67 -CIATS-GPGATNLITGLADALLDSVPVVaitgqvsspLIGTDAF-------------QEidvlgLSLACTKHSFL---- 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 152 rywdrITRPEQLMSSLLRAFEVmtdpAKA---GPATICISQDVEGEAYDFDESFFVKrvhyIDRMQPSERELQGAAELIK 228
Cdd:PRK08978 128 -----VQSLEELPEIMAEAFEI----ASSgrpGPVLVDIPKDIQLAEGELEPHLTTV----ENEPAFPAAELEQARALLA 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 229 SSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYT 308
Cdd:PRK08978 195 QAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVATLKGLGAVEADHPYYLGMLGMHGTKAANLAVQECDLLIAVGARFD 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 309 DFATSSKTAFDfDKAKFLNINVSRMQAYKLDAfqvvadAKVTL-GKLHGLLEGYESEfgTTIrelkDEWLAERERL-SKV 386
Cdd:PRK08978 275 DRVTGKLNTFA-PHAKVIHLDIDPAEINKLRQ------AHVALqGDLNALLPALQQP--LNI----DAWRQHCAQLrAEH 341
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 387 TFKREAFDPEIknhfsqevlneYADALntelpqttaLLTINETIPEDSVIIC--------SAgslpgdlQRLWHSNVPNt 458
Cdd:PRK08978 342 AWRYDHPGEAI-----------YAPAL---------LKQLSDRKPADTVVTTdvgqhqmwVA-------QHMRFTRPEN- 393
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 459 yHL-EYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGS 537
Cdd:PRK08978 394 -FItSSGLGTMGFGLPAAIGAQVARPDDTVICVSGDGSFMMNVQELGTIKRKQLPVKIVLLDNQRLGMVRQWQQLFFDER 472
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1324265562 538 yYCEFRTDDNQilnvDYAKVAEGYGAKTYRANTVEELKAALE 579
Cdd:PRK08978 473 -YSETDLSDNP----DFVMLASAFGIPGQTITRKDQVEAALD 509
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
54-603 |
6.87e-39 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 151.18 E-value: 6.87e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 54 DAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIYAVSTsvGPGAANLVAAAGTALANNIPVLLI---PADTFATRQpdpVL 130
Cdd:PRK08199 43 DETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFVTR--GPGATNASIGVHTAFQDSTPMILFvgqVARDFRERE---AF 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 131 QqmEQEYSAAITtndalkPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVegeaydFDESFFV--KRVH 208
Cdd:PRK08199 118 Q--EIDYRRMFG------PMAKWVAEIDDAARIPELVSRAFHVATS-GRPGPVVLALPEDV------LSETAEVpdAPPY 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 209 YIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLG--GMGITG 286
Cdd:PRK08199 183 RRVAAAPGAADLARLAELLARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACAFRRQDLFDNRHPNYAGdlGLGINP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 287 TLAAnkAARQADLIIGIGTRYTDFATSSKTAFD--FDKAKFLNIN-----VSRMqaYKLDaFQVVADAKVTLGKLHGLLE 359
Cdd:PRK08199 263 ALAA--RIREADLVLAVGTRLGEVTTQGYTLLDipVPRQTLVHVHpdaeeLGRV--YRPD-LAIVADPAAFAAALAALEP 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 360 GYESEFGTTIRELKDEWLAERERLskvtFKREAFD-PEIKNHfsqevlneyadalntelpqttalltINETIPEDSVIIC 438
Cdd:PRK08199 338 PASPAWAEWTAAAHADYLAWSAPL----PGPGAVQlGEVMAW-------------------------LRERLPADAIITN 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 439 SAGSLPGDLQRLWHSNVPNTYhLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLF 518
Cdd:PRK08199 389 GAGNYATWLHRFFRFRRYRTQ-LAPTSGSMGYGLPAAIAAKLLFPERTVVAFAGDGCFLMNGQELATAVQYGLPIIVIVV 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 519 DNSGFGCINNLQMDHGSGsyycefRTDDNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLPKT 598
Cdd:PRK08199 468 NNGMYGTIRMHQEREYPG------RVSGTDLTNPDFAALARAYGGHGETVERTEDFAPAFERALASGKPALIEIRIDPEA 541
|
....*
gi 1324265562 599 MTDGY 603
Cdd:PRK08199 542 ITPTA 546
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
93-594 |
1.64e-38 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 149.74 E-value: 1.64e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 93 GPGAANLVAAAGTALANNIPVLLIP----ADTFATRQ------PDpvlQQmeqeysaaittnDALKPVSRYWDRITRPEQ 162
Cdd:PRK07524 73 GPGMTNIATAMGQAYADSIPMLVISsvnrRASLGKGRgklhelPD---QR------------AMVAGVAAFSHTLMSAED 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 163 LMSSLLRAFEVMtDPAKAGPATICISQDVEGEAYDFDESFFVKRVhyiDRMQPSERELQGAAELIKSSKKPVILVGGGTK 242
Cdd:PRK07524 138 LPEVLARAFAVF-DSARPRPVHIEIPLDVLAAPADHLLPAPPTRP---ARPGPAPAALAQAAERLAAARRPLILAGGGAL 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 243 ysGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGmgiTGTLAANKA-ARQADLIIGIGTRY--TDFATSSKTAFD 319
Cdd:PRK07524 214 --AAAAALRALAERLDAPVALTINAKGLLPAGHPLLLGA---SQSLPAVRAlIAEADVVLAVGTELgeTDYDVYFDGGFP 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 320 FDkAKFLNINVSRMQAYK--LDAFQVVADAKVTLGKLHGLLEGyesefgttiRELKDEWLAERerlskVTFKREAFDPEI 397
Cdd:PRK07524 289 LP-GELIRIDIDPDQLARnyPPALALVGDARAALEALLARLPG---------QAAAADWGAAR-----VAALRQALRAEW 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 398 knhfsqevlneyaDALntELPQTTALLTINETIPE-----DSVIICSAGSLPGDL--QRLWhsnvpntYHLEYGYSCMGY 470
Cdd:PRK07524 354 -------------DPL--TAAQVALLDTILAALPDaifvgDSTQPVYAGNLYFDAdaPRRW-------FNASTGYGTLGY 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 471 EVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEfrtddnqIL 550
Cdd:PRK07524 412 GLPAAIGAALGAPERPVVCLVGDGGLQFTLPELASAVEADLPLIVLLWNNDGYGEIRRYMVARDIEPVGVD-------PY 484
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1324265562 551 NVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK07524 485 TPDFIALARAFGCAAERVADLEQLQAALRAAFARPGPTLIEVDQ 528
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
33-597 |
1.66e-38 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 150.30 E-value: 1.66e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQALeQDAGHLKVYQgKNEQGMAHAAMAYSKqmLRRKIYAVSTSVGPGAANLVAAAGTALANN 110
Cdd:PRK07710 29 EGVEVIFGYpgGAVLPLYDAL-YDCGIPHILT-RHEQGAIHAAEGYAR--ISGKPGVVIATSGPGATNVVTGLADAMIDS 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 111 IPVL---------LIPADTFatrQPDPVLqqmeqeysaAITTndalkPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAG 181
Cdd:PRK07710 105 LPLVvftgqvatsVIGSDAF---QEADIM---------GITM-----PVTKHNYQVRKASDLPRIIKEAFHIATT-GRPG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 182 PATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPL 261
Cdd:PRK07710 167 PVLIDIPKDMVVEEGEFCYDVQMDLPGYQPNYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQEIPV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 262 VETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDfDKAKFLNINVSRMQAYKL--D 339
Cdd:PRK07710 247 VHTLLGLGGFPADHPLFLGMAGMHGTYTANMALYECDLLINIGARFDDRVTGNLAYFA-KEATVAHIDIDPAEIGKNvpT 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 340 AFQVVADAKVTLGKLHgLLEGYESEfgttirelKDEW---LAERERLSKVTFKREAfdPEIKNHFSQEVLNEYADAlnte 416
Cdd:PRK07710 326 EIPIVADAKQALQVLL-QQEGKKEN--------HHEWlslLKNWKEKYPLSYKRNS--ESIKPQKAIEMLYEITKG---- 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 417 lpqttalltinetipeDSVIICSAGSlpgdlQRLWHS-----NVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIV 491
Cdd:PRK07710 391 ----------------EAIVTTDVGQ-----HQMWAAqyypfKTPDKWVTSGGLGTMGFGLPAAIGAQLAKPDETVVAIV 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 492 GDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQmdhgsgSYYCEFRTDDNQILNV-DYAKVAEGYGAKTYRANT 570
Cdd:PRK07710 450 GDGGFQMTLQELSVIKELSLPVKVVILNNEALGMVRQWQ------EEFYNQRYSHSLLSCQpDFVKLAEAYGIKGVRIDD 523
|
570 580
....*....|....*....|....*..
gi 1324265562 571 VEELKAALEDAKKQDVSTLIEMKVLPK 597
Cdd:PRK07710 524 ELEAKEQLQHAIELQEPVVIDCRVLQS 550
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
4-591 |
4.40e-38 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 148.99 E-value: 4.40e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 4 KIRLTTAQALIKFLNQqyihvdgkeepfvEGIFTIFGHgnvlgIGQA------LEQDAGhLKVYQGKNEQGMAHAAMAYS 77
Cdd:PRK07525 3 KMKMTPSEAFVETLQA-------------HGITHAFGI-----IGSAfmdasdLFPPAG-IRFIDVAHEQNAGHMADGYT 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 78 KqmLRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLI-P-ADTFATRQPDpvLQQMEQEysaaittnDALKPVSRYWD 155
Cdd:PRK07525 64 R--VTGRMGMVIGQNGPGITNFVTAVATAYWAHTPVVLVtPqAGTKTIGQGG--FQEAEQM--------PMFEDMTKYQE 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 156 RITRPEQLMSSLLRAFevmtDPAKA--GPATICISQDVEGEAYDFDesffVKRVHYIDRMQPSERELQGAAELIKSSKKP 233
Cdd:PRK07525 132 EVRDPSRMAEVLNRVF----DKAKResGPAQINIPRDYFYGVIDVE----IPQPVRLERGAGGEQSLAEAAELLSEAKFP 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 234 VILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATS 313
Cdd:PRK07525 204 VILSGAGVVLSDAIEECKALAERLDAPVACGYLHNDAFPGSHPLWVGPLGYNGSKAAMELIAKADVVLALGTRLNPFGTL 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 314 SKTAFDF--DKAKFL--NINVSRMQAYKLDAFQVVADAKVT----LGKLHGLLEGYES--EFGTTIRELKDEWLAErerL 383
Cdd:PRK07525 284 PQYGIDYwpKDAKIIqvDINPDRIGLTKKVSVGICGDAKAVarelLARLAERLAGDAGreERKALIAAEKSAWEQE---L 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 384 SKVTFKREAFDPEiknhfsqevLNEYADALNTEL--PQtTALLTINETIPEDSVI------ICSAGslpgdlqrlwhsnv 455
Cdd:PRK07525 361 SSWDHEDDDPGTD---------WNEEARARKPDYmhPR-QALREIQKALPEDAIVstdignNCSIA-------------- 416
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 456 pNTY--------HLEYGY--SCmGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGC 525
Cdd:PRK07525 417 -NSYlrfekgrkYLAPGSfgNC-GYAFPAIIGAKIACPDRPVVGFAGDGAWGISMNEVMTAVRHNWPVTAVVFRNYQWGA 494
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1324265562 526 INNLQMDhgsgsYYcefrtDDNQI-----LNVDYAKVAEGYGAKTYRANTVEELKAALEDA---KKQDVSTLIE 591
Cdd:PRK07525 495 EKKNQVD-----FY-----NNRFVgteldNNVSYAGIAEAMGAEGVVVDTQEELGPALKRAidaQNEGKTTVIE 558
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
33-581 |
1.78e-37 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 147.37 E-value: 1.78e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQALEQDAG--HLKVyqgKNEQGMAHAAMAYSKQMlrRKIYAVSTSVGPGAANLVAAAGTALA 108
Cdd:PRK06882 17 EGVEYVFGYpgGSVLDIYDAIHTLGGieHVLV---RHEQAAVHMADGYARST--GKVGCVLVTSGPGATNAITGIATAYT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 109 NNIPVLLIPADTFATRQPDPVLQQMEqeySAAITtndalKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICIS 188
Cdd:PRK06882 92 DSVPLVILSGQVPSNLIGTDAFQECD---MLGIS-----RPVVKHSFIVKNAEDIPSTIKKAFYIAST-GRPGPVVIDIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 189 QDVEGEAYDFDESF--FVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQA 266
Cdd:PRK06882 163 KDMVNPANKFTYEYpeEVSLRSYNPTVQGHKGQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQKLNLPVTSSLM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 267 GKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFdFDKAKFLNINVSRMQAYK--LDAFQVV 344
Cdd:PRK06882 243 GLGAYPSTDKQFLGMLGMHGTYEANNAMHESDLILGIGVRFDDRTTNNLAKY-CPNAKVIHIDIDPTSISKnvPAYIPIV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 345 ADAKVTLGKLHGLLEgyESEFGTTIRELKDEWLAERERLSKVTFKREAFDPEIKnhfSQEVLneyadalntelpQTTALL 424
Cdd:PRK06882 322 GSAKNVLEEFLSLLE--EENLAKSQTDLTAWWQQINEWKAKKCLEFDRTSDVIK---PQQVV------------EAIYRL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 425 TINETIPEDSV---IICSAGSLPGDLQRLWHSNvpntyhleYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHS 501
Cdd:PRK06882 385 TNGDAYVASDVgqhQMFAALHYPFDKPRRWINS--------GGAGTMGFGLPAAIGVKFAHPEATVVCVTGDGSIQMNIQ 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 502 ELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRtddNQIlnVDYAKVAEGYGAKTYRANTVEELKAALEDA 581
Cdd:PRK06882 457 ELSTAKQYDIPVVIVSLNNRFLGMVKQWQDLIYSGRHSQVYM---NSL--PDFAKLAEAYGHVGIQIDTPDELEEKLTQA 531
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
33-584 |
5.36e-36 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 142.68 E-value: 5.36e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQALEQDAG--HLKVyqgKNEQGMAHAAMAYSKQMlrRKIYAVSTSVGPGAANLVAAAGTALA 108
Cdd:PRK07979 17 QGVKQVFGYpgGAVLDIYDALHTVGGidHVLV---RHEQAAVHMADGLARAT--GEVGVVLVTSGPGATNAITGIATAYM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 109 NNIPVLLIPAdtfatrqpdpvlqqmeqEYSAAITTNDAL---------KPVSRYWDRITRPEQLMSSLLRAFEVMTDpAK 179
Cdd:PRK07979 92 DSIPLVVLSG-----------------QVATSLIGYDAFqecdmvgisRPVVKHSFLVKQTEDIPQVLKKAFWLAAS-GR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 180 AGPATICISQDVEGEA----YDFDESffVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISE 255
Cdd:PRK07979 154 PGPVVVDLPKDILNPAnklpYVWPES--VSMRSYNPTTQGHKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 256 AYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFdFDKAKFLNINVSRMQA 335
Cdd:PRK07979 232 KLNLPVVSSLMGLGAFPATHRQSLGMLGMHGTYEANMTMHNADVIFAVGVRFDDRTTNNLAKY-CPNATVLHIDIDPTSI 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 336 YKLDA--FQVVADAKVTLGKLHGLLEGYESEfgTTIRELKDEWLAERERLSKVTFKREAFDPEIKNHFSQEVLNeyadal 413
Cdd:PRK07979 311 SKTVTadIPIVGDARQVLEQMLELLSQESAH--QPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLW------ 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 414 ntELPQTTALLTINETIPEdsviICSAGSLPGDLQRLWHSNvpntyhleYGYSCMGYEVSGTLGLKLAHPDREVYSIVGD 493
Cdd:PRK07979 383 --RLTKGDAYVTSDVGQHQ----MFAALYYPFDKPRRWINS--------GGLGTMGFGLPAALGVKMALPEETVVCVTGD 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 494 GSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQ-MDHG---SGSYYCEFRtddnqilnvDYAKVAEGYGAKTYRAN 569
Cdd:PRK07979 449 GSIQMNIQELSTALQYELPVLVLNLNNRYLGMVKQWQdMIYSgrhSQSYMQSLP---------DFVRLAEAYGHVGIQIS 519
|
570
....*....|....*
gi 1324265562 570 TVEELKAALEDAKKQ 584
Cdd:PRK07979 520 HPDELESKLSEALEQ 534
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
58-596 |
1.05e-35 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 141.51 E-value: 1.05e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 58 LKVYQGKNEQGMAHAAMAYSKqmLRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLIPADTfatrQPDPVLQQMEQEY 137
Cdd:PRK06457 40 VKYVQVRHEEGAALAASVEAK--ITGKPSACMGTSGPGSIHLLNGLYDAKMDHAPVIALTGQV----ESDMIGHDYFQEV 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 138 SAAITTNDalkpVSRYWDRITRPEQLMSSLLRAF-EVMTdpaKAGPATICISQDV--EGEAYDFDESFFVKRVHYidrmq 214
Cdd:PRK06457 114 NLTKLFDD----VAVFNQILINPENAEYIIRRAIrEAIS---KRGVAHINLPVDIlrKSSEYKGSKNTEVGKVKY----- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 215 psERELQGAAELIKSSKKPVILVGGGTKysGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAA 294
Cdd:PRK06457 182 --SIDFSRAKELIKESEKPVLLIGGGTR--GLGKEINRFAEKIGAPIIYTLNGKGILPDLDPKVMGGIGLLGTKPSIEAM 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 295 RQADLIIGIGTR--YTDFATSS-------------------KTAFDFDKAKFLNINVSRmqayKLDAFqvvadakvtlgk 353
Cdd:PRK06457 258 DKADLLIMLGTSfpYVNFLNKSakviqvdidnsnigkrldvDLSYPIPVAEFLNIDIEE----KSDKF------------ 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 354 lhgllegYESefgttIRELKDEWLaerERLSKVTFKReafDPEIKnhfsqevlneyadalntelPQTTALLtINETIPED 433
Cdd:PRK06457 322 -------YEE-----LKGKKEDWL---DSISKQENSL---DKPMK-------------------PQRVAYI-VSQKCKKD 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 434 SVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLA-HPDREVYSIVGDGSFLMLHSELITAIQYNKK 512
Cdd:PRK06457 364 AVIVTDTGNVTMWTARHFRASGEQTFIFSAWLGSMGIGVPGSVGASFAvENKRQVISFVGDGGFTMTMMELITAKKYDLP 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 513 INVLLFDNSGFGCINNLQMDHGsgsyYCEFRTDdnqILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEM 592
Cdd:PRK06457 444 VKIIIYNNSKLGMIKFEQEVMG----YPEWGVD---LYNPDFTKIAESIGFKGFRLEEPKEAEEIIEEFLNTKGPAVLDA 516
|
....
gi 1324265562 593 KVLP 596
Cdd:PRK06457 517 IVDP 520
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
34-596 |
6.36e-35 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 139.90 E-value: 6.36e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 34 GIFTIFGHGnvlgIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIYAVSTSVGPGAANLVAAAGTALANNIPV 113
Cdd:PRK06112 28 GVEQIFGQS----LPSALFLAAEAIGIRQIAYRTENAGGAMADGYARVSGKVAVVTAQNGPAATLLVAPLAEALKASVPI 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 114 LLIPADTfATRQPDP-VLQQMEQeysAAIttndaLKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICISQDVE 192
Cdd:PRK06112 104 VALVQDV-NRDQTDRnAFQELDH---IAL-----FQSCTKWVRRVTVAERIDDYVDQAFTAATS-GRPGPVVLLLPADLL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 193 GEAydfDESFFVKRV----HY-IDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAG 267
Cdd:PRK06112 174 TAA---AAAPAAPRSnslgHFpLDRTVPAPQRLAEAASLLAQAQRPVVVAGGGVHISGASAALAALQSLAGLPVATTNMG 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 268 KSTVeaDFANNLGGmGITGTLAANKA--------ARQADLIIGIGTRYTDFATSSKTAFDFDkAKFLNINVSRMQAYK-L 338
Cdd:PRK06112 251 KGAV--DETHPLSL-GVVGSLMGPRSpgrhlrdlVREADVVLLVGTRTNQNGTDSWSLYPEQ-AQYIHIDVDGEEVGRnY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 339 DAFQVVADAKVTLGKLHGLLEGYesefGTTIRELKDEWLAERERLSkvtfkREAFDPEiknhfSQEVLNEYADALNTE-- 416
Cdd:PRK06112 327 EALRLVGDARLTLAALTDALRGR----DLAARAGRRAALEPAIAAG-----REAHRED-----SAPVALSDASPIRPEri 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 417 LPQTTALLTINETIPEDSviicSAGSlpgdlqrLWHSNV-----PNTYHLE-YGYSCMGYEVSGTLGLKLAHPDREVYSI 490
Cdd:PRK06112 393 MAELQAVLTGDTIVVADA----SYSS-------IWVANFltarrAGMRFLTpRGLAGLGWGVPMAIGAKVARPGAPVICL 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 491 VGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGcinnLQMdHGSGSYYCEFrTDDNQILNVDYAKVAEGYGAKTYRANT 570
Cdd:PRK06112 462 VGDGGFAHVWAELETARRMGVPVTIVVLNNGILG----FQK-HAETVKFGTH-TDACHFAAVDHAAIARACGCDGVRVED 535
|
570 580
....*....|....*....|....*.
gi 1324265562 571 VEELKAALEDAKKQDVSTLIEMKVLP 596
Cdd:PRK06112 536 PAELAQALAAAMAAPGPTLIEVITDP 561
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
33-584 |
8.33e-35 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 139.34 E-value: 8.33e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGhgnVLGIG-----QALEQdAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIYAVSTSvGPGAANLVAAAGTAL 107
Cdd:PRK11269 17 EGVTTAFG---VPGAAinpfySAMRK-HGGIRHILARHVEGASHMAEGYTRATAGNIGVCIGTS-GPAGTDMITGLYSAS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 108 ANNIPVLLIpadtfaTRQ-PDPVLQQmeqEYSAAITTNDALKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATIC 186
Cdd:PRK11269 92 ADSIPILCI------TGQaPRARLHK---EDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRS-GRPGPVLID 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 187 ISQDVEGEAYDFDESFFVKRVHYidRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQA 266
Cdd:PRK11269 162 LPFDVQVAEIEFDPDTYEPLPVY--KPAATRAQIEKALEMLNAAERPLIVAGGGVINADASDLLVEFAELTGVPVIPTLM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 267 GKSTVEADFANNLGGMGI-TGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFDKaKFLNINVSRMQAYKLDA--FQV 343
Cdd:PRK11269 240 GWGAIPDDHPLMAGMVGLqTSHRYGNATLLASDFVLGIGNRWANRHTGSVEVYTKGR-KFVHVDIEPTQIGRVFGpdLGI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 344 VADAKVTLGKLHGLLEGYESEfgttiRELKD--EWLAE-RERlsKVTFKReafdpeiKNHFS------QEVLNEyadaln 414
Cdd:PRK11269 319 VSDAKAALELLVEVAREWKAA-----GRLPDrsAWVADcQER--KRTLLR-------KTHFDnvpikpQRVYEE------ 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 415 telpqttalltINETIPEDSVIICSAGslpgdLQRLWHSNVPNTYHLEYGYSC-----MGYEVSGTLGLKLAHPDREVYS 489
Cdd:PRK11269 379 -----------MNKAFGRDTCYVSTIG-----LSQIAAAQFLHVYKPRHWINCgqagpLGWTIPAALGVRAADPDRNVVA 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 490 IVGDGSFLMLHSELITAIQYN-KKINVLLfDNSGFGCINNLQ----MDhgsgsyYC---EFRTDDNQILN---VDYAKVA 558
Cdd:PRK11269 443 LSGDYDFQFLIEELAVGAQFNlPYIHVLV-NNAYLGLIRQAQrafdMD------YCvqlAFENINSPELNgygVDHVKVA 515
|
570 580
....*....|....*....|....*.
gi 1324265562 559 EGYGAKTYRANTVEELKAALEDAKKQ 584
Cdd:PRK11269 516 EGLGCKAIRVFKPEDIAPALEQAKAL 541
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
4-596 |
1.60e-34 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 138.30 E-value: 1.60e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 4 KIRLTTAQALIKFLNQQyihvdgkeepfveGIFTIFG--HGNVLGIGQAL-------------EQDAGHLKvyqgkneQG 68
Cdd:PRK08155 10 RKRFTGAELIVRLLERQ-------------GIRIVTGipGGAILPLYDALsqstqirhilarhEQGAGFIA-------QG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 69 MAHAA------MAYSkqmlrrkiyavstsvGPGAANLVAAAGTALANNIPVLLIPAdtfatrqpdpvlqqmeQEYSAAIT 142
Cdd:PRK08155 70 MARTTgkpavcMACS---------------GPGATNLVTAIADARLDSIPLVCITG----------------QVPASMIG 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 143 TnDALKPVSRYwdRITRP-----------EQLMSSLLRAFEVMTDpAKAGPATICISQDVEGEAYDFDESFFVKRVHYID 211
Cdd:PRK08155 119 T-DAFQEVDTY--GISIPitkhnylvrdiEELPQVISDAFRIAQS-GRPGPVWIDIPKDVQTAVIELEALPAPAEKDAAP 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 212 rmQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAAN 291
Cdd:PRK08155 195 --AFDEESIRDAAAMINAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGARSTN 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 292 KAARQADLIIGIGTRYTDFATsSKTAFDFDKAKFLNINVSRMQAYKLDAFQVV--ADAKVTLGKLHGLLEgyesefgtti 369
Cdd:PRK08155 273 YILQEADLLIVLGARFDDRAI-GKTEQFCPNAKIIHVDIDRAELGKIKQPHVAiqADVDDVLAQLLPLVE---------- 341
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 370 RELKDEWLAERERLskvtfKREaFDPEIKNhfSQEVLNEYAdalnteLPQTTAlltinETIPEDSVIICSAGSlpgdlQR 449
Cdd:PRK08155 342 AQPRAEWHQLVADL-----QRE-FPCPIPK--ADDPLSHYG------LINAVA-----ACVDDNAIITTDVGQ-----HQ 397
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 450 LWHS-----NVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFG 524
Cdd:PRK08155 398 MWTAqayplNRPRQWLTSGGLGTMGFGLPAAIGAALANPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIILMNNEALG 477
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1324265562 525 CINNLQ-MDHGSGSYYCEFRTddnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLI------EMKVLP 596
Cdd:PRK08155 478 LVHQQQsLFYGQRVFAATYPG------KINFMQIAAGFGLETCDLNNEADPQAALQEAINRPGPALIhvridaEEKVYP 550
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
426-596 |
5.47e-34 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 127.65 E-value: 5.47e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 426 INETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELIT 505
Cdd:cd02014 11 LNKRAPDDAIFTIDVGNVTVWAARHLRMNGKQRFILSGLLATMGNGLPGAIAAKLAYPDRQVIALSGDGGFAMLMGDLIT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 506 AIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRtddnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQD 585
Cdd:cd02014 91 AVKYNLPVIVVVFNNSDLGFIKWEQEVMGQPEFGVDLP-------NPDFAKIAEAMGIKGIRVEDPDELEAALDEALAAD 163
|
170
....*....|.
gi 1324265562 586 VSTLIEMKVLP 596
Cdd:cd02014 164 GPVVIDVVTDP 174
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
33-580 |
3.73e-33 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 134.45 E-value: 3.73e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQALEQ--DAGHLKVyqgKNEQGMAHAAMAYSKQMLRRKIYAVsTSvGPGAANLVAAAGTALA 108
Cdd:PRK09107 24 QGVEHIFGYpgGAVLPIYDEIFQqdDIQHILV---RHEQGAGHAAEGYARSTGKPGVVLV-TS-GPGATNAVTPLQDALM 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 109 NNIPVL---------LIPADTFatRQPDPVlqqmeqeysaAITtndalKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAK 179
Cdd:PRK09107 99 DSIPLVcitgqvpthLIGSDAF--QECDTV----------GIT-----RPCTKHNWLVKDVNDLARVIHEAFHVATS-GR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 180 AGPATICISQDVEgeaydFDESFFVK------RVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSG--ARDELV 251
Cdd:PRK09107 161 PGPVVVDIPKDVQ-----FATGTYTPpqkapvHVSYQPKVKGDAEAITEAVELLANAKRPVIYSGGGVINSGpeASRLLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 252 AISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDfDKAKFLNINV- 330
Cdd:PRK09107 236 ELVELTGFPITSTLMGLGAYPASGKNWLGMLGMHGTYEANMAMHDCDVMLCVGARFDDRITGRLDAFS-PNSKKIHIDId 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 331 --SRMQAYKLDaFQVVADAKVTLGKlhgLLEGYESEFGTTIRELKDEWLAERERLSKV-TFKREAFDPEIKNHFSQEVLN 407
Cdd:PRK09107 315 psSINKNVRVD-VPIIGDVGHVLED---MLRLWKARGKKPDKEALADWWGQIARWRARnSLAYTPSDDVIMPQYAIQRLY 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 408 EyadalntelpqttalLTINetipEDSVIICSAGSlpgdlQRLW-----HSNVPNTYHLEYGYSCMGYEVSGTLGLKLAH 482
Cdd:PRK09107 391 E---------------LTKG----RDTYITTEVGQ-----HQMWaaqffGFEEPNRWMTSGGLGTMGYGLPAALGVQIAH 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 483 PDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQ-MDHG---SGSYycefrTDDNQilnvDYAKVA 558
Cdd:PRK09107 447 PDALVIDIAGDASIQMCIQEMSTAVQYNLPVKIFILNNQYMGMVRQWQqLLHGnrlSHSY-----TEAMP----DFVKLA 517
|
570 580
....*....|....*....|..
gi 1324265562 559 EGYGAKTYRANTVEELKAALED 580
Cdd:PRK09107 518 EAYGAVGIRCEKPGDLDDAIQE 539
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
33-581 |
1.87e-32 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 132.18 E-value: 1.87e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQAL--EQDAGHLKVyqgKNEQGMAHAAMAYSKQMLRRKIYAVSTsvGPGAANLVAAAGTALA 108
Cdd:PRK06466 17 EGVEYIYGYpgGAVLHIYDALfkQDKVEHILV---RHEQAATHMADGYARATGKTGVVLVTS--GPGATNAITGIATAYM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 109 NNIPVLLIPADTFATRQPDPVLQQMEQeysAAITtndalKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICIS 188
Cdd:PRK06466 92 DSIPMVVLSGQVPSTLIGEDAFQETDM---VGIS-----RPIVKHSFMVKHASEIPEIIKKAFYIAQS-GRPGPVVVDIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 189 QDVEGEAYDFdESFFVKRVHyIDRMQPSER----ELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVET 264
Cdd:PRK06466 163 KDMTNPAEKF-EYEYPKKVK-LRSYSPAVRghsgQIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTELAHLLNLPVTNT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 265 QAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFdFDKAKFLNINVSRMQAYKldafQVV 344
Cdd:PRK06466 241 LMGLGGFPGTDRQFLGMLGMHGTYEANMAMHHADVILAVGARFDDRVTNGPAKF-CPNAKIIHIDIDPASISK----TIK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 345 ADAKVTlgklhGLLEGYESEFGTTIRELK---------------DEWLAERErlskvTFKREAFDPEIKNhfsqevlney 409
Cdd:PRK06466 316 ADIPIV-----GPVESVLTEMLAILKEIGekpdkealaawwkqiDEWRGRHG-----LFPYDKGDGGIIK---------- 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 410 adalntelPQtTALLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYS 489
Cdd:PRK06466 376 --------PQ-QVVETLYEVTNGDAYVTSDVGQHQMFAAQYYKFNKPNRWINSGGLGTMGFGLPAAMGVKLAFPDQDVAC 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 490 IVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQ-MDHGS--GSYYCEFRTddnqilnvDYAKVAEGYGAKTY 566
Cdd:PRK06466 447 VTGEGSIQMNIQELSTCLQYGLPVKIINLNNGALGMVRQWQdMQYEGrhSHSYMESLP--------DFVKLAEAYGHVGI 518
|
570
....*....|....*
gi 1324265562 567 RANTVEELKAALEDA 581
Cdd:PRK06466 519 RITDLKDLKPKLEEA 533
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
426-594 |
9.51e-32 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 121.24 E-value: 9.51e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 426 INETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELIT 505
Cdd:cd02010 8 LRAVMGDDDIVLLDVGAHKIWMARYYRTYAPNTCLISNGLATMGVALPGAIGAKLVYPDRKVVAVSGDGGFMMNSQELET 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 506 AIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRtddnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQD 585
Cdd:cd02010 88 AVRLKIPLVVLIWNDNGYGLIKWKQEKEYGRDSGVDFG-------NPDFVKYAESFGAKGYRIESADDLLPVLERALAAD 160
|
....*....
gi 1324265562 586 VSTLIEMKV 594
Cdd:cd02010 161 GVHVIDCPV 169
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
223-597 |
9.64e-32 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 129.89 E-value: 9.64e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 223 AAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGG-MGITGTLAANKAARQADLII 301
Cdd:COG3961 202 AAERLAKAKRPVILAGVEVHRFGLQEELLALAEKTGIPVATTLLGKSVLDESHPQFIGTyAGAASSPEVREYVENADCVL 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 302 GIGTRYTDFATSSKTAfDFDKAKFLNINVSRMQ-AYKldAFQVVAdakvtlgkLHGLLEGyesefgttirelkdewlaer 380
Cdd:COG3961 282 CLGVVFTDTNTGGFTA-QLDPERTIDIQPDSVRvGGH--IYPGVS--------LADFLEA-------------------- 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 381 erLSKVTFKREAFDPeiknhFSQEVLNEYADALNTELPQTTALLTINETIPEDSVIICSAGS---------LPGDlqrlw 451
Cdd:COG3961 331 --LAELLKKRSAPLP-----APAPPPPPPPAAPDAPLTQDRLWQRLQAFLDPGDIVVADTGTslfgaadlrLPEG----- 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 452 hsnvpNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGcINnlQM 531
Cdd:COG3961 399 -----ATFIAQPLWGSIGYTLPAALGAALAAPDRRVILLVGDGAFQLTAQELSTMLRYGLKPIIFVLNNDGYT-IE--RA 470
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 532 DHGSGSYYcefrtddNQILNVDYAKVAEGYGAK---TYRANTVEELKAALEDAKK-QDVSTLIEMkVLPK 597
Cdd:COG3961 471 IHGPDGPY-------NDIANWDYAKLPEAFGGGnalGFRVTTEGELEEALAAAEAnTDRLTLIEV-VLDK 532
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
33-579 |
2.12e-31 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 129.09 E-value: 2.12e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQALEQDAGHLKVYQgKNEQGMAHAAMAYSKQMLRRKIyAVSTSvGPGAANLVAAAGTALANN 110
Cdd:PLN02470 26 EGVDTVFAYpgGASMEIHQALTRSNCIRNVLC-RHEQGEVFAAEGYAKASGKVGV-CIATS-GPGATNLVTGLADALLDS 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 111 IPVL---------LIPADTFatrQPDPVLqqmeqEYSAAITTNDALKPVSRYWDRITRpeqlmssllRAFEVMTDpAKAG 181
Cdd:PLN02470 103 VPLVaitgqvprrMIGTDAF---QETPIV-----EVTRSITKHNYLVMDVEDIPRVIR---------EAFFLASS-GRPG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 182 PATICISQDVEGEAYDFDESFFVKRVHYIDRMQ--PSERELQGAAELIKSSKKPVILVGGGTkySGARDELVAISEAYNI 259
Cdd:PLN02470 165 PVLVDIPKDIQQQLAVPNWNQPMKLPGYLSRLPkpPEKSQLEQIVRLISESKRPVVYVGGGC--LNSSEELREFVELTGI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 260 PLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDfDKAKFLNINV--SRMQAYK 337
Cdd:PLN02470 243 PVASTLMGLGAFPASDELSLQMLGMHGTVYANYAVDSADLLLAFGVRFDDRVTGKLEAFA-SRASIVHIDIdpAEIGKNK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 338 LDAFQVVADAKVTLGKLHGLLEgyesEFGTTIRELKdEWLAE-RERLSKVTFKREAFDPEIKNHFSQEVLNEyadalnte 416
Cdd:PLN02470 322 QPHVSVCADVKLALQGLNKLLE----ERKAKRPDFS-AWRAElDEQKEKFPLSYPTFGDAIPPQYAIQVLDE-------- 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 417 lpqttalltinetIPEDSVIICS---------AGSLPGDLQRLWHSNVpntyhleyGYSCMGYEVSGTLGLKLAHPDREV 487
Cdd:PLN02470 389 -------------LTDGNAIISTgvgqhqmwaAQWYKYKEPRRWLTSG--------GLGAMGFGLPAAIGAAAANPDAIV 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 488 YSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQ---MDHGSGSYYCEFRTDDNQILNvDYAKVAEGYGAK 564
Cdd:PLN02470 448 VDIDGDGSFIMNIQELATIHVENLPVKIMVLNNQHLGMVVQWEdrfYKANRAHTYLGDPDAEAEIFP-DFLKFAEGCKIP 526
|
570
....*....|....*
gi 1324265562 565 TYRANTVEELKAALE 579
Cdd:PLN02470 527 AARVTRKSDLREAIQ 541
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
34-595 |
2.30e-31 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 128.57 E-value: 2.30e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 34 GIFTIFG----HGnvLGIGQALEQDaGHLKVYQGKNEQGMAHAAMAYSKQmlRRKIYAVSTSVGPGAANLVAAAGTALAN 109
Cdd:PRK07064 17 GVKTAFGvisiHN--MPILDAIGRR-GKIRFVPARGEAGAVNMADAHARV--SGGLGVALTSTGTGAGNAAGALVEALTA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 110 NIPVLLIPAdtfatrqpdpvlqQMEQEY----SAAI-TTNDA---LKPVSRYWDRITRPEQLMSSLLRAFEV-MTDPAka 180
Cdd:PRK07064 92 GTPLLHITG-------------QIETPYldqdLGYIhEAPDQltmLRAVSKAAFRVRSAETALATIREAVRVaLTAPT-- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 181 GPATICISQDVEGEAYDFDESFFVKRVhyiDRMQPSERELQGAAELIKSSKKPVILVGGGTKysGARDELVAISEAyNIP 260
Cdd:PRK07064 157 GPVSVEIPIDIQAAEIELPDDLAPVHV---AVPEPDAAAVAELAERLAAARRPLLWLGGGAR--HAGAEVKRLVDL-GFG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 261 LVETQAGKSTVEADFANNLGGMGITGtlAANKAARQADLIIGIGTRYTDFATSSKT--------AFDFDKAKflninVSR 332
Cdd:PRK07064 231 VVTSTQGRGVVPEDHPASLGAFNNSA--AVEALYKTCDLLLVVGSRLRGNETLKYSlalprpliRVDADAAA-----DGR 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 333 mqAYKLDAFqVVADAKVTLGKLHGLLEGYES---EFGTTIRELKDEwlAERERlskvtfkREAFDPeiknhfsqevlneY 409
Cdd:PRK07064 304 --GYPNDLF-VHGDAARVLARLADRLEGRLSvdpAFAADLRAAREA--AVADL-------RKGLGP-------------Y 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 410 ADaLNTELPQttalltineTIPEDSVI---ICSAGSLPGDlqRLWHSNVPNT--YHLEYGyscMGYEVSGTLGLKLAHPD 484
Cdd:PRK07064 359 AK-LVDALRA---------ALPRDGNWvrdVTISNSTWGN--RLLPIFEPRAnvHALGGG---IGQGLAMAIGAALAGPG 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 485 REVYSIVGDGSFlMLH-SELITAIQYNKKINVLLFDNSGFGCINNLQmdhgsgSYYCEFRTDDNQILNVDYAKVAEGYGA 563
Cdd:PRK07064 424 RKTVGLVGDGGL-MLNlGELATAVQENANMVIVLMNDGGYGVIRNIQ------DAQYGGRRYYVELHTPDFALLAASLGL 496
|
570 580 590
....*....|....*....|....*....|..
gi 1324265562 564 KTYRANTVEELKAALEDAKKQDVSTLIEMKVL 595
Cdd:PRK07064 497 PHWRVTSADDFEAVLREALAKEGPVLVEVDML 528
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
33-583 |
1.39e-30 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 126.84 E-value: 1.39e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 33 EGIFTIFGH--GNVLGIGQAL-EQDA-GHLKVyqgKNEQGMAHAAMAYSKQMLRRKIyAVSTSvGPGAANLVAAAGTALA 108
Cdd:PRK06965 34 EGVEFIWGYpgGAVLYIYDELyKQDKiQHVLV---RHEQAAVHAADGYARATGKVGV-ALVTS-GPGVTNAVTGIATAYM 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 109 NNIPVLLIPADTfatrqPDPVL-QQMEQEYSAAITTndalKPVSRYWDRITRPEQLMSSLLRAFEVMTDpAKAGPATICI 187
Cdd:PRK06965 109 DSIPMVVISGQV-----PTAAIgQDAFQECDTVGIT----RPIVKHNFLVKDVRDLAETVKKAFYIART-GRPGPVVVDI 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 188 SQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAG 267
Cdd:PRK06965 179 PKDVSKTPCEYEYPKSVEMRSYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGVILANASRELRQLADLLGYPVTNTLMG 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 268 KSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFDKAKFLNINV---SRMQAYKLDaFQVV 344
Cdd:PRK06965 259 LGAYPASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRVIGNPAHFASRPRKIIHIDIdpsSISKRVKVD-IPIV 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 345 ADAKVTLGKLHGLLEgyESEFGTTIRELKDEWLAERERLSKVTFKREAFDPEIKNHFSQEVLNEYADAlntelpqttall 424
Cdd:PRK06965 338 GDVKEVLKELIEQLQ--TAEHGPDADALAQWWKQIEGWRSRDCLKYDRESEIIKPQYVVEKLWELTDG------------ 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 425 tinetipeDSVIICSAGSlpgdlQRLWHS-----NVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLML 499
Cdd:PRK06965 404 --------DAFVCSDVGQ-----HQMWAAqfyrfNEPRRWINSGGLGTMGVGLPYAMGIKMAHPDDDVVCITGEGSIQMC 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 500 HSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRtddnQILNvDYAKVAEGYGAKTYRANTVEELKAALE 579
Cdd:PRK06965 471 IQELSTCLQYDTPVKIISLNNRYLGMVRQWQEIEYSKRYSHSYM----DALP-DFVKLAEAYGHVGMRIEKTSDVEPALR 545
|
....
gi 1324265562 580 DAKK 583
Cdd:PRK06965 546 EALR 549
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
64-592 |
9.06e-30 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 124.33 E-value: 9.06e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 64 KNEQGMAHAAMAYSKqmLRRKIYAVSTSVGPGAANLV---------AAAGTALANNIPVLLIPADTFATRQPDPVLQQme 134
Cdd:PRK06546 48 RHEEAAAFAAAAEAQ--LTGKLAVCAGSCGPGNLHLInglydahrsGAPVLAIASHIPSAQIGSGFFQETHPDRLFVE-- 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 135 qeysaaittndalkpVSRYWDRITRPEQlMSSLLRAfEVMTDPAKAGPATICISQDVEGE--AYDFDESFFVKRVhyiDR 212
Cdd:PRK06546 124 ---------------CSGYCEMVSSAEQ-APRVLHS-AIQHAVAGGGVSVVTLPGDIADEpaPEGFAPSVISPRR---PT 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 213 MQPSERELQGAAELIKSSKKPVILVGGGTKysGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANK 292
Cdd:PRK06546 184 VVPDPAEVRALADAINEAKKVTLFAGAGVR--GAHAEVLALAEKIKAPVGHSLRGKEWIQYDNPFDVGMSGLLGYGAAHE 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 293 AARQADLIIGIGTR--YTDFATSSKTA-FDFDKAkflniNVSRMQayKLDaFQVVADAKVTLGKLHGLLEGyesefgTTI 369
Cdd:PRK06546 262 AMHEADLLILLGTDfpYDQFLPDVRTAqVDIDPE-----HLGRRT--RVD-LAVHGDVAETIRALLPLVKE------KTD 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 370 RELKDEWLAERER-LSKVTfkrEAFDPEIKNHfsQEVLNEYADALntelpqttalltINETIPEDSVIICSAGslpgdLQ 448
Cdd:PRK06546 328 RRFLDRMLKKHARkLEKVV---GAYTRKVEKH--TPIHPEYVASI------------LDELAADDAVFTVDTG-----MC 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 449 RLWHSN--VPNTYHLEYG---YSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGF 523
Cdd:PRK06546 386 NVWAARyiTPNGRRRVIGsfrHGSMANALPHAIGAQLADPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKVVVFNNSTL 465
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1324265562 524 GCInNLQM------DHGsgsyycefrTDDNqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEM 592
Cdd:PRK06546 466 GMV-KLEMlvdglpDFG---------TDHP---PVDYAAIAAALGIHAVRVEDPKDVRGALREAFAHPGPALVDV 527
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
32-189 |
1.10e-27 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 109.16 E-value: 1.10e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 32 VEGIFTIFGHGNvLGIGQALEQDagHLKVYQGKNEQGMAHAAMAYSkqMLRRKIYAVSTSVGPGAANLVAAAGTALANNI 111
Cdd:cd07035 12 VDHVFGVPGGAI-LPLLDALARS--GIRYILVRHEQGAVGMADGYA--RATGKPGVVLVTSGPGLTNAVTGLANAYLDSI 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1324265562 112 PVLLIPADTFATRQPDPVLQQMEQeysaaittNDALKPVSRYWDRITRPEQLMSSLLRAFEVMTDPAKaGPATICISQ 189
Cdd:cd07035 87 PLLVITGQRPTAGEGRGAFQEIDQ--------VALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRP-GPVALDLPK 155
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
421-594 |
1.09e-26 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 106.85 E-value: 1.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 421 TALLTINETIPEDSvIICSAGSLPGDLQRLWHSNV-PNTYhLEYG-YSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLM 498
Cdd:cd02004 3 RVLHELQEALPDDA-IIVSDGGNTMDWARYILRPRkPRHR-LDAGtFGTLGVGLGYAIAAALARPDKRVVLVEGDGAFGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 499 LHSELITAIQYNKKINVLLFDNSGFGCINNLQ--MDHGSGSYYCEFRtddnqilNVDYAKVAEGYGAKTYRANTVEELKA 576
Cdd:cd02004 81 SGMELETAVRYNLPIVVVVGNNGGWYQGLDGQqlSYGLGLPVTTLLP-------DTRYDLVAEAFGGKGELVTTPEELKP 153
|
170
....*....|....*...
gi 1324265562 577 ALEDAKKQDVSTLIEMKV 594
Cdd:cd02004 154 ALKRALASGKPALINVII 171
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
71-581 |
3.41e-26 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 113.17 E-value: 3.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 71 HAAMAYSkqMLRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLIPADTFATRQPD------PVLQQMEQEYSAAITTN 144
Cdd:PRK08327 64 SMAHGYA--LVTGKPQAVMVHVDVGTANALGGVHNAARSRIPVLVFAGRSPYTEEGElgsrntRIHWTQEMRDQGGLVRE 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 145 dALKpvsryWD-RITRPEQLMSSLLRAFEVM-TDPAkaGPATICISQDVEGEAydfdesffVKRVHYIDRMQPSERE--- 219
Cdd:PRK08327 142 -YVK-----WDyEIRRGDQIGEVVARAIQIAmSEPK--GPVYLTLPREVLAEE--------VPEVKADAGRQMAPAPpap 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 220 ----LQGAAELIKSSKKPVILvgggTKYSGAR----DELVAISEAYNIPLVETQAGKSTVEADFANNLGGMgITGTLAan 291
Cdd:PRK08327 206 dpedIARAAEMLAAAERPVII----TWRAGRTaegfASLRRLAEELAIPVVEYAGEVVNYPSDHPLHLGPD-PRADLA-- 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 292 kaarQADLIIGIGTRYTDFATSSKTAFDfdkAKFLNINV----SRMQAYkldAFQV----VADAKVTLGKLHGLLEGYES 363
Cdd:PRK08327 279 ----EADLVLVVDSDVPWIPKKIRPDAD---ARVIQIDVdplkSRIPLW---GFPCdlciQADTSTALDQLEERLKSLAS 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 364 EFGTTIRELKDEWLAERERLSKVtfKREAfdpeiknhfsqevlneyADALNTELPQTTALLT--INETIPEDSVIICSAG 441
Cdd:PRK08327 349 AERRRARRRRAAVRELRIRQEAA--KRAE-----------------IERLKDRGPITPAYLSycLGEVADEYDAIVTEYP 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 442 SLPGDLQRlwhsNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSE--LITAIQYNKKINVLLFD 519
Cdd:PRK08327 410 FVPRQARL----NKPGSYFGDGSAGGLGWALGAALGAKLATPDRLVIATVGDGSFIFGVPEaaHWVAERYGLPVLVVVFN 485
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1324265562 520 NSGFGCI-NNLQMDHGSG-----SYYCEFRTDDnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDA 581
Cdd:PRK08327 486 NGGWLAVkEAVLEVYPEGyaarkGTFPGTDFDP----RPDFAKIAEAFGGYGERVEDPEELKGALRRA 549
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
425-594 |
1.34e-25 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 103.83 E-value: 1.34e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 425 TINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYScMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELI 504
Cdd:cd02002 9 ALAAALPEDAIIVDEAVTNGLPLRDQLPLTRPGSYFTLRGGG-LGWGLPAAVGAALANPDRKVVAIIGDGSFMYTIQALW 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 505 TAIQYNKKINVLLFDNSGFgciNNLQMDhgSGSYYCEFRTDDNQIL------NVDYAKVAEGYGAKTYRANTVEELKAAL 578
Cdd:cd02002 88 TAARYGLPVTVVILNNRGY---GALRSF--LKRVGPEGPGENAPDGldlldpGIDFAAIAKAFGVEAERVETPEELDEAL 162
|
170
....*....|....*.
gi 1324265562 579 EDAKKQDVSTLIEMKV 594
Cdd:cd02002 163 REALAEGGPALIEVVV 178
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
467-599 |
4.36e-24 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 99.88 E-value: 4.36e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 467 CMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQ-MdhgsgsYYCEFRTD 545
Cdd:cd02015 51 TMGFGLPAAIGAKVARPDKTVICIDGDGSFQMNIQELATAAQYNLPVKIVILNNGSLGMVRQWQeL------FYEGRYSH 124
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1324265562 546 DNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLPKTM 599
Cdd:cd02015 125 TTLDSNPDFVKLAEAYGIKGLRVEKPEELEAALKEALASDGPVLLDVLVDPEEN 178
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
212-581 |
6.28e-24 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 106.23 E-value: 6.28e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 212 RMQPSERELQGAAELIKSSKKPVILVGGGTkySGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAAN 291
Cdd:PRK09124 183 VVTPAEEELRKLAALLNGSSNITLLCGSGC--AGAHDELVALAETLKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGY 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 292 KAARQADLIIGIGTrytDFATSsktAFDFDKAKFLNINvsrmqaykLDAFQVVADAKVTLGklhglLEGyesEFGTTIRE 371
Cdd:PRK09124 261 HAMMNCDTLLMLGT---DFPYR---QFYPTDAKIIQID--------INPGSLGRRSPVDLG-----LVG---DVKATLAA 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 372 LkdewlaererLSKVTFKREafdpeikNHFSQEVLNEYA------DALNTELPQTTAL----LT--INETIPEDSVIICS 439
Cdd:PRK09124 319 L----------LPLLEEKTD-------RKFLDKALEHYRkarkglDDLAVPSDGGKPIhpqyLArqISEFAADDAIFTCD 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 440 AGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFD 519
Cdd:PRK09124 382 VGTPTVWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQAAHPGRQVVALSGDGGFSMLMGDFLSLVQLKLPVKIVVFN 461
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1324265562 520 NSGFGCInNLQMDHGSgsyYCEFRTDdnqILNVDYAKVAEGYGAKTYRANTVEELKAALEDA 581
Cdd:PRK09124 462 NSVLGFV-AMEMKAGG---YLTDGTD---LHNPDFAAIAEACGITGIRVEKASELDGALQRA 516
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
87-594 |
4.75e-22 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 100.31 E-value: 4.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 87 AVSTSvGPGAANLVAAAGTALANNIPVLLIpadTFATRQPDpVLQQMEQeysaAITTNDALKPVSRYWDRITRPEQLMSS 166
Cdd:PRK08617 71 VLVTS-GPGVSNLATGLVTATAEGDPVVAI---GGQVKRAD-RLKRTHQ----SMDNVALFRPITKYSAEVQDPDNLSEV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 167 LLRAFEVMTDpAKAGPATICISQDV-----EGEAydfdesffVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGT 241
Cdd:PRK08617 142 LANAFRAAES-GRPGAAFVSLPQDVvdapvTSKA--------IAPLSKPKLGPASPEDINYLAELIKNAKLPVLLLGMRA 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 242 KYSGARDELVAISEAYNIPLVETQAGKSTV----EADFANNLGgmgitgtLAANKAA----RQADLIIGIGtrytdfats 313
Cdd:PRK08617 213 SSPEVTAAIRRLLERTNLPVVETFQAAGVIsrelEDHFFGRVG-------LFRNQPGdellKKADLVITIG--------- 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 314 sktafdFD----KAKFLN-------INVSRMQAYKLDAFQ----VVADAKVTLGKLHGLLEGYesEFGTTIRELKDEWLA 378
Cdd:PRK08617 277 ------YDpieyEPRNWNsegdatiIHIDVLPAEIDNYYQpereLIGDIAATLDLLAEKLDGL--SLSPQSLEILEELRA 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 379 ERERLSKVTFKREAFdpeiKNHFSQEVlneyadalntelpqttalLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNT 458
Cdd:PRK08617 349 QLEELAERPARLEEG----AVHPLRII------------------RALQDIVTDDTTVTVDVGSHYIWMARYFRSYEPRH 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 459 YHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQM---DHGS 535
Cdd:PRK08617 407 LLFSNGMQTLGVALPWAIAAALVRPGKKVVSVSGDGGFLFSAMELETAVRLKLNIVHIIWNDGHYNMVEFQEEmkyGRSS 486
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 1324265562 536 GsyyCEFRtddnqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK08617 487 G---VDFG-------PVDFVKYAESFGAKGLRVTSPDELEPVLREALATDGPVVIDIPV 535
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
34-596 |
1.01e-21 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 99.60 E-value: 1.01e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 34 GIFTIFGH-GN-VLGIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKqMLRRKIYAVSTSvGPGAANLVAAAGTALANNI 111
Cdd:PRK08273 17 GVRRVFGYpGDgINGLLGALGRADDKPEFVQARHEEMAAFMAVAHAK-FTGEVGVCLATS-GPGAIHLLNGLYDAKLDHV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 112 PVLLIpadtfatrqpdpVLQQ----MEQEYSAAITTNDALKPV-SRYWDRITRPEQLMSSLLRAFEVMTdpAKAGPATIC 186
Cdd:PRK08273 95 PVVAI------------VGQQaraaLGGHYQQEVDLQSLFKDVaGAFVQMVTVPEQLRHLVDRAVRTAL--AERTVTAVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 187 ISQDVEGEAYDFDESFFvKRVH-----YIDRMQPSERELQGAAELIKSSKKPVILVGGGTKysGARDELVAISEAYNIPL 261
Cdd:PRK08273 161 LPNDVQELEYEPPPHAH-GTVHsgvgyTRPRVVPYDEDLRRAAEVLNAGRKVAILVGAGAL--GATDEVIAVAERLGAGV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 262 VETQAGKSTVEADFANNLGGMGITGTLAANKAARQAD--LIIGIGTRYTDFATssktafDFDKAKFLNINV-SRMQA--Y 336
Cdd:PRK08273 238 AKALLGKAALPDDLPWVTGSIGLLGTKPSYELMRECDtlLMVGSSFPYSEFLP------KEGQARGVQIDIdGRMLGlrY 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 337 KLDAfQVVADAKVTLGKLHGLLEGYESefgTTIRELKDEWLAERERlskvTFKREAFDPeiknhfsqevlneyADALNte 416
Cdd:PRK08273 312 PMEV-NLVGDAAETLRALLPLLERKKD---RSWRERIEKWVARWWE----TLEARAMVP--------------ADPVN-- 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 417 lPQTTALlTINETIPEDSVIICSAGS----------LPGDLQRlwhsnvpntyHLEYGYSCMGYEVSGTLGLKLAHPDRE 486
Cdd:PRK08273 368 -PQRVFW-ELSPRLPDNAILTADSGScanwyardlrMRRGMMA----------SLSGTLATMGPAVPYAIAAKFAHPDRP 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 487 VYSIVGDGSFLMLH-SELITAIQY-----NKKINVLLFDNsgfgciNNLQM-------DHGSGsyycefRTDDNQIL-NV 552
Cdd:PRK08273 436 VIALVGDGAMQMNGmAELITVAKYwrqwsDPRLIVLVLNN------RDLNQvtweqrvMEGDP------KFEASQDLpDV 503
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1324265562 553 DYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLP 596
Cdd:PRK08273 504 PYARFAELLGLKGIRVDDPEQLGAAWDEALAADRPVVLEVKTDP 547
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
10-191 |
1.28e-21 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 92.30 E-value: 1.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 10 AQALIKFLNQQYihvdgkeepfVEGIFTIFGhGNVLGIGQALEQDAGhLKVYQGKNEQGMAHAAMAYSKqmLRRKIYAVS 89
Cdd:pfam02776 2 AEALADVLKALG----------VDTVFGVPG-GHILPLLDALAKSPG-IRYVLTRHEQGAAFAADGYAR--ATGKPGVVL 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 90 TSVGPGAANLVAAAGTALANNIPVLLIPADTFATRQPDPVLQQMeqeysaaITTNDALKPVSRYWDRITRPEQLMSSLLR 169
Cdd:pfam02776 68 VTSGPGATNALTGLANAYVDSVPLLVISGQRPRSLVGRGALQQE-------LDQLALFRPVTKWAVRVTSADEIPEVLRR 140
|
170 180
....*....|....*....|..
gi 1324265562 170 AFEVMTDPaKAGPATICISQDV 191
Cdd:pfam02776 141 AFRAALSG-RPGPVYLEIPLDV 161
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
425-597 |
2.28e-21 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 91.83 E-value: 2.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 425 TINETIPEDSVIICSAGS---------LPGDL----QRLWHSnvpntyhleygyscMGYEVSGTLGLKLAHPDREVYSIV 491
Cdd:cd02005 10 QVQNFLKPNDILVAETGTswfgaldlkLPKGTrfisQPLWGS--------------IGYSVPAALGAALAAPDRRVILLV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 492 GDGSFLMLHSELITAIQYNKKINVLLFDNSGFGcInnLQMDHGSGSYYcefrtddNQILNVDYAKVAE----GYGAKTYR 567
Cdd:cd02005 76 GDGSFQMTVQELSTMIRYGLNPIIFLINNDGYT-I--ERAIHGPEASY-------NDIANWNYTKLPEvfggGGGGLSFR 145
|
170 180 190
....*....|....*....|....*....|.
gi 1324265562 568 ANTVEELKAALEDAKKQ-DVSTLIEMkVLPK 597
Cdd:cd02005 146 VKTEGELDEALKDALFNrDKLSLIEV-ILPK 175
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
32-496 |
1.01e-16 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 83.62 E-value: 1.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 32 VEGIFTIFGhGNVLGIGQALEQDAghLKVYQGKNEQGMAHAAMAYSKqMLRRKIYAVSTSvGPGAANLVAAAGTALANNI 111
Cdd:PRK05858 20 VDTMFTLSG-GHLFPLYDGAREEG--IRLIDVRHEQTAAFAAEAWAK-LTRVPGVAVLTA-GPGVTNGMSAMAAAQFNQS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 112 PVLLIPADTFATRQPDPVLQQMEQEysaaittnDALKPVSRYWDRITRPEQLMSSLLRAFEVMTDPAKaGPATICISQDV 191
Cdd:PRK05858 95 PLVVLGGRAPALRWGMGSLQEIDHV--------PFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHR-GPVFVDFPMDH 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 192 ---EGEAYDFDESFFVKRVhyidRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGK 268
Cdd:PRK05858 166 afsMADDDGRPGALTELPA----GPTPDPDALARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 269 STVEADFAnnlggmgITGTLAANKAARQADLIIGIGTRyTDFatssKTAF-DF-DKAKFLNINVSRMQaykLDAFQVVAd 346
Cdd:PRK05858 242 GVVPADHP-------LAFSRARGKALGEADVVLVVGVP-MDF----RLGFgVFgGTAQLVHVDDAPPQ---RAHHRPVA- 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 347 akvtlGKLHGLLEGYESEFGTTIRELKD--EWLAERERLSKVTFKREAfdpeiknhfsqEVLNEYADALN-----TELpq 419
Cdd:PRK05858 306 -----AGLYGDLSAILSALAGAGGDRTDhqGWIEELRTAETAARARDA-----------AELADDRDPIHpmrvyGEL-- 367
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1324265562 420 ttalltiNETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYhLEYG-YSCMGYEVSGTLGLKLAHPDREVYSIVGDGSF 496
Cdd:PRK05858 368 -------APLLDRDAIVIGDGGDFVSYAGRYIDPYRPGCW-LDPGpFGCLGTGPGYALAARLARPSRQVVLLQGDGAF 437
|
|
| TPP_PpyrDC |
cd03371 |
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of ... |
422-596 |
2.69e-15 |
|
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. These proteins require TPP and divalent metal cation cofactors.
Pssm-ID: 239468 [Multi-domain] Cd Length: 188 Bit Score: 74.66 E-value: 2.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 422 ALLTINETIPEDSVIICSAGSLPGDLQRLwhSNVPNTYHLE--YGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLML 499
Cdd:cd03371 4 AIEIVLSRAPATAAVVSTTGMTSRELFEL--RDRPGGGHAQdfLTVGSMGHASQIALGIALARPDRKVVCIDGDGAALMH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 500 HSELITAIQYNKK--INVlLFDNsgfGCinnlqmdHGS--GSYYCEFRTDDNQIlnvdyAKvAEGYgAKTYRANTVEELK 575
Cdd:cd03371 82 MGGLATIGGLAPAnlIHI-VLNN---GA-------HDSvgGQPTVSFDVSLPAI-----AK-ACGY-RAVYEVPSLEELV 143
|
170 180
....*....|....*....|.
gi 1324265562 576 AALEDAKKQDVSTLIEMKVLP 596
Cdd:cd03371 144 AALAKALAADGPAFIEVKVRP 164
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
86-595 |
4.61e-15 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 78.46 E-value: 4.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 86 YAVSTSvGPGAANLVAAAG---------TALANNIPvLLIPA--DTFATRQPDPVLqqmeqeysAAITTNDALKPVSRYW 154
Cdd:PRK07092 67 YAQATG-NAAFVNLHSAAGvgnamgnlfTAFKNHTP-LVITAgqQARSILPFEPFL--------AAVQAAELPKPYVKWS 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 155 DRITRPEQLMSSLLRAFEVMTDPAKaGPATICISQDvegeayDFD---ESFFVKRVHYidRMQPSERELQGAAELIKSSK 231
Cdd:PRK07092 137 IEPARAEDVPAAIARAYHIAMQPPR-GPVFVSIPYD------DWDqpaEPLPARTVSS--AVRPDPAALARLGDALDAAR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 232 KPVILVGGGTKYSGARDELVAISEAYNIPL-VETQAGKSTVEAD---FANNLGGM--GITGTLAANkaarqaDLIIGIGT 305
Cdd:PRK07092 208 RPALVVGPAVDRAGAWDDAVRLAERHRAPVwVAPMSGRCSFPEDhplFAGFLPASreKISALLDGH------DLVLVIGA 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 306 ---RYTDFATSSKtafdFDKAKFLninvsrmqaykldaFQVVADAKVT----LGklhgllegyESEFGTTIRELKDewLA 378
Cdd:PRK07092 282 pvfTYHVEGPGPH----LPEGAEL--------------VQLTDDPGEAawapMG---------DAIVGDIRLALRD--LL 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 379 ERERLSKvtfkREAFDPEiknhfsqeVLNEYADALNTELPQTTALLTINETIPEDSVIICSAGSLPGdlqrLWHSNVPNT 458
Cdd:PRK07092 333 ALLPPSA----RPAPPAR--------PMPPPAPAPGEPLSVAFVLQTLAALRPADAIVVEEAPSTRP----AMQEHLPMR 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 459 YHLEYGYSC---MGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINN----LQM 531
Cdd:PRK07092 397 RQGSFYTMAsggLGYGLPAAVGVALAQPGRRVIGLIGDGSAMYSIQALWSAAQLKLPVTFVILNNGRYGALRWfapvFGV 476
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1324265562 532 DHGSGsyycefrTDdnqILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVL 595
Cdd:PRK07092 477 RDVPG-------LD---LPGLDFVALARGYGCEAVRVSDAAELADALARALAADGPVLVEVEVA 530
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
422-596 |
1.57e-13 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 69.46 E-value: 1.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 422 ALLTINETIPEDSVI------ICSAGSlpgdlQRLWHSNvPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGS 495
Cdd:cd02013 9 VLRELEKAMPEDAIVstdignICSVAN-----SYLRFEK-PRSFIAPLSFGNCGYALPAIIGAKAAAPDRPVVAIAGDGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 496 FLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGsyycefRTDDNQILNVDYAKVAEGYGAKTYRANTVEELK 575
Cdd:cd02013 83 WGMSMMEIMTAVRHKLPVTAVVFRNRQWGAEKKNQVDFYNN------RFVGTELESESFAKIAEACGAKGITVDKPEDVG 156
|
170 180
....*....|....*....|....
gi 1324265562 576 AALEDA---KKQDVSTLIEMKVLP 596
Cdd:cd02013 157 PALQKAiamMAEGKTTVIEIVCDQ 180
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
34-591 |
2.14e-12 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 70.01 E-value: 2.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 34 GIFTIFGhgnVLGIGQA----LEQDAGhLKVYQGKNEQGMAHAAmAYSKQMLRRKIYAVSTSvGPGAANLVAAAGTALAN 109
Cdd:PRK09259 24 GIDTIYG---VVGIPITdlarLAQAEG-IRYIGFRHEQSAGNAA-AAAGFLTQKPGVCLTVS-APGFLNGLTALANATTN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 110 NIPVLLIPADTfaTRQ-PDpvLQQ-----MEQeYSAAittndalKPVSRYWDRITRPEQLMSSLLRAFE---------VM 174
Cdd:PRK09259 98 CFPMIMISGSS--EREiVD--LQQgdyeeLDQ-LNAA-------KPFCKAAFRVNRAEDIGIGVARAIRtavsgrpggVY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 175 TD-PAKAgpaticISQDVEGEAydfDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAI 253
Cdd:PRK09259 166 LDlPAKV------LAQTMDADE---ALTSLVKVVDPAPAQLPAPEAVDRALDLLKKAKRPLIILGKGAAYAQADEQIREF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 254 SEAYNIPLVETQAGKSTVEADFANNLGGmgitgtlAANKAARQADLIIGIGTR------YTDFATSSKTafdfdkAKF-- 325
Cdd:PRK09259 237 VEKTGIPFLPMSMAKGLLPDTHPQSAAA-------ARSLALANADVVLLVGARlnwllsHGKGKTWGAD------KKFiq 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 326 LNINVSRMQAYKLDAFQVVADAKVTLGKlhgLLEGYESEFGTTIRELKDEWLAERER-LSKVTfKREAFDPEIKNHFSqe 404
Cdd:PRK09259 304 IDIEPQEIDSNRPIAAPVVGDIGSVMQA---LLAGLKQNTFKAPAEWLDALAERKEKnAAKMA-EKLSTDTQPMNFYN-- 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 405 vlneyadalntelpqttALLTINETIPED-SVIICSAGSLPGDLQRlwhsNVPNTYHLEYGYSC---------MGYEVSG 474
Cdd:PRK09259 378 -----------------ALGAIRDVLKENpDIYLVNEGANTLDLAR----NIIDMYKPRHRLDCgtwgvmgigMGYAIAA 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 475 TLglklaHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFgcinnlqmdhgsgsyyceFRTDDNQILNVD- 553
Cdd:PRK09259 437 AV-----ETGKPVVAIEGDSAFGFSGMEVETICRYNLPVTVVIFNNGGI------------------YRGDDVNLSGAGd 493
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1324265562 554 -----------YAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIE 591
Cdd:PRK09259 494 psptvlvhharYDKMMEAFGGVGYNVTTPDELRHALTEAIASGKPTLIN 542
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
468-583 |
1.30e-11 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 64.22 E-value: 1.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 468 MGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQ----MDHGSGSYYCEFR 543
Cdd:cd02006 59 LGWTVPAALGVAAADPDRQVVALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLGLIRQAQrafdMDYQVNLAFENIN 138
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1324265562 544 TDDNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKK 583
Cdd:cd02006 139 SSELGGYGVDHVKVAEGLGCKAIRVTKPEELAAAFEQAKK 178
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
217-594 |
8.52e-09 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 58.56 E-value: 8.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 217 ERELQGAAELIKSSKKPVILVGGGTKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGM-GITGTLAANKAAR 295
Cdd:PLN02573 211 EAAVEAAAEFLNKAVKPVLVGGPKLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHHPHFIGTYwGAVSTPFCAEIVE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 296 QADLIIGIGTRYTDFATSSKTAFdFDKAKFLNINVSRmqaykldafqvvadakVTLGklHGllegyeSEFGTTIreLKDE 375
Cdd:PLN02573 291 SADAYLFAGPIFNDYSSVGYSLL-LKKEKAIIVQPDR----------------VTIG--NG------PAFGCVL--MKDF 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 376 WLAERERLSKVT-----FKReAFDPEiknhfSQEVLNEYADALNTE---------LPQTTALltINETipEDSVIICSAG 441
Cdd:PLN02573 344 LEALAKRVKKNTtayenYKR-IFVPE-----GEPLKSEPGEPLRVNvlfkhiqkmLSGDTAV--IAET--GDSWFNCQKL 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 442 SLPGDLQrlwhsnvpntYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLfdns 521
Cdd:PLN02573 414 KLPEGCG----------YEFQMQYGSIGWSVGATLGYAQAAPDKRVIACIGDGSFQVTAQDVSTMIRCGQKSIIFL---- 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 522 gfgcINNlqmdhgsGSYYCEFRTDD---NQILNVDYAKVAE----GYG-AKTYRANTVEELKAALEDA--KKQDVSTLIE 591
Cdd:PLN02573 480 ----INN-------GGYTIEVEIHDgpyNVIKNWNYTGLVDaihnGEGkCWTAKVRTEEELIEAIATAtgEKKDCLCFIE 548
|
...
gi 1324265562 592 MKV 594
Cdd:PLN02573 549 VIV 551
|
|
| TPP_ComE |
cd03372 |
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins ... |
432-597 |
1.89e-08 |
|
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins similar to Methanococcus jannaschii sulfopyruvate decarboxylase beta subunit (ComE). M. jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits, which catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. ComDE requires TPP and divalent metal cation cofactors.
Pssm-ID: 239469 [Multi-domain] Cd Length: 179 Bit Score: 54.22 E-value: 1.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 432 EDSVIICSAGSLPGDLQRLWHSNVpNTYHLeygySCMGYEVSGTLGLKLAHPdREVYSIVGDGSFLMLHSELITAIQYN- 510
Cdd:cd03372 13 KDELVVSNIGFPSKELYAAGDRPL-NFYML----GSMGLASSIGLGLALAQP-RKVIVIDGDGSLLMNLGALATIAAEKp 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 511 KKINVLLFDNSGFGCINNlQMDHGSgsyycefrtddnqiLNVDYAKVAEGYG-AKTYRANTVEELKAALEDAKKQdvSTL 589
Cdd:cd03372 87 KNLIIVVLDNGAYGSTGN-QPTHAG--------------KKTDLEAVAKACGlDNVATVASEEAFEKAVEQALDG--PSF 149
|
....*...
gi 1324265562 590 IEMKVLPK 597
Cdd:cd03372 150 IHVKIKPG 157
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
472-594 |
1.17e-07 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 51.83 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 472 VSGTLGLKLAHPDReVYSIVGD-------GSFLMLHselitaiQYNKKINVLLFDNSGFGCINNL-QMDHGSgsyycEFR 543
Cdd:cd02009 57 LSTALGIALATDKP-TVLLTGDlsflhdlNGLLLGK-------QEPLNLTIVVINNNGGGIFSLLpQASFED-----EFE 123
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1324265562 544 TDDNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:cd02009 124 RLFGTPQGLDFEHLAKAYGLEYRRVSSLDELEQALESALAQDGPHVIEVKT 174
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
431-591 |
4.44e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 52.95 E-value: 4.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 431 PEDSVIICSAGSLPGDLQRLWHSNVPNTyHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYN 510
Cdd:PRK12474 355 PDQAIYADEALTSGLFFDMSYDRARPHT-HLPLTGGSIGQGLPLAAGAAVAAPDRKVVCPQGDGGAAYTMQALWTMAREN 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 511 KKINVLLFDNSGFGCIN-NLQMDHGSGSYYCEFRTDDNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTL 589
Cdd:PRK12474 434 LDVTVVIFANRSYAILNgELQRVGAQGAGRNALSMLDLHNPELNWMKIAEGLGVEASRATTAEEFSAQYAAAMAQRGPRL 513
|
..
gi 1324265562 590 IE 591
Cdd:PRK12474 514 IE 515
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
476-594 |
1.03e-06 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 51.77 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 476 LGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCE----FRTDDNQIln 551
Cdd:PRK07586 395 TGAAVACPDRKVLALQGDGSAMYTIQALWTQARENLDVTTVIFANRAYAILRGELARVGAGNPGPRaldmLDLDDPDL-- 472
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1324265562 552 vDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKV 594
Cdd:PRK07586 473 -DWVALAEGMGVPARRVTTAEEFADALAAALAEPGPHLIEAVV 514
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
467-590 |
4.46e-06 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 47.27 E-value: 4.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 467 CMGYEVSGTLGLKLAHPDREVYSIVGDGSFlmLHS---ELITAIqYNK-KINVLLFDNS-----GfgcinnlQMDH-GSG 536
Cdd:cd02008 52 CMGASIGVAIGMAKASEDKKVVAVIGDSTF--FHSgilGLINAV-YNKaNITVVILDNRttamtG-------GQPHpGTG 121
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1324265562 537 SYYCEFRTddnqilNVDYAKVAEGYGAK------TYRAN-TVEELKAALEdakKQDVSTLI 590
Cdd:cd02008 122 KTLTEPTT------VIDIEALVRAIGVKrvvvvdPYDLKaIREELKEALA---VPGVSVII 173
|
|
| TPP_ComE_PpyrDC |
cd02001 |
Thiamine pyrophosphate (TPP) family, ComE and PpyrDC subfamily, TPP-binding module; composed ... |
468-596 |
4.03e-05 |
|
Thiamine pyrophosphate (TPP) family, ComE and PpyrDC subfamily, TPP-binding module; composed of proteins similar to sulfopyruvate decarboxylase beta subunit (ComE) and phosphonopyruvate decarboxylase (Ppyr decarboxylase). Methanococcus jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits which, catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. Ppyr decarboxylase is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. Ppyr decarboxylase and ComDE require TPP and divalent metal cation cofactors.
Pssm-ID: 238959 [Multi-domain] Cd Length: 157 Bit Score: 44.40 E-value: 4.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 468 MGYEVSGTLGLKLAHPdREVYSIVGDGSFLMLHSELITAIQYN-KKINVLLFDNSGFGCINNlQMDHGSgsyycefrtdd 546
Cdd:cd02001 44 MGLAGSIGLGLALGLS-RKVIVVDGDGSLLMNPGVLLTAGEFTpLNLILVVLDNRAYGSTGG-QPTPSS----------- 110
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1324265562 547 nqilNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLP 596
Cdd:cd02001 111 ----NVNLEAWAAACGYLVLSAPLLGGLGSEFAGLLATTGPTLLHAPIAP 156
|
|
| TPP_TK |
cd02012 |
Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK ... |
449-593 |
2.92e-04 |
|
Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.
Pssm-ID: 238970 [Multi-domain] Cd Length: 255 Bit Score: 42.88 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 449 RLWHSNVPNtyHLEYGYScMGYEVS-GTLG------------LKLAHPDREVYSIVGDGSfLMlhsELIT--AIQY--NK 511
Cdd:cd02012 82 RQLGSRLPG--HPEYGLT-PGVEVTtGSLGqglsvavgmalaEKLLGFDYRVYVLLGDGE-LQ---EGSVweAASFagHY 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 512 KIN--VLLFDNsgfgciNNLQMDhgsgsyyceFRTDDnQILNVDYAKVAEGYGAKTYRA--NTVEELKAALEDAKKQ-DV 586
Cdd:cd02012 155 KLDnlIAIVDS------NRIQID---------GPTDD-ILFTEDLAKKFEAFGWNVIEVdgHDVEEILAALEEAKKSkGK 218
|
....*..
gi 1324265562 587 STLIEMK 593
Cdd:cd02012 219 PTLIIAK 225
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
32-185 |
3.20e-03 |
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Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 38.48 E-value: 3.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 32 VEGIFTIFGHGNVLGIGQALEQDagHLKVYQGKNEQGMAHAAMAYSKQMLRRkiyAVSTSVGPGAANLVAAAGTALANNI 111
Cdd:cd06586 12 VRHVFGYPGDEISSLLDALREGD--KRIIDTVIHELGAAGAAAGYARAGGPP---VVIVTSGTGLLNAINGLADAAAEHL 86
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90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1324265562 112 PVLlipadtFATRQPDPVLQ--QMEQEysaaITTNDALKPVSRYWDRITRPEQLMSSLLRAFEvmTDPAKAGPATI 185
Cdd:cd06586 87 PVV------FLIGARGISAQakQTFQS----MFDLGMYRSIPEANISSPSPAELPAGIDHAIR--TAYASQGPVVV 150
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| PRK06163 |
PRK06163 |
hypothetical protein; Provisional |
463-520 |
4.13e-03 |
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hypothetical protein; Provisional
Pssm-ID: 235721 [Multi-domain] Cd Length: 202 Bit Score: 39.04 E-value: 4.13e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1324265562 463 YGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELIT-AIQYNKKINVLLFDN 520
Cdd:PRK06163 54 YMLGSMGLAFPIALGVALAQPKRRVIALEGDGSLLMQLGALGTiAALAPKNLTIIVMDN 112
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| PRK05899 |
PRK05899 |
transketolase; Reviewed |
545-593 |
7.42e-03 |
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transketolase; Reviewed
Pssm-ID: 235639 [Multi-domain] Cd Length: 586 Bit Score: 39.35 E-value: 7.42e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1324265562 545 DDNQI---------LNVDYAKVAEGYGAKTYRA--NTVEELKAALEDAKKQDVSTLIEMK 593
Cdd:PRK05899 187 DDNRIsidgptegwFTEDVKKRFEAYGWHVIEVdgHDVEAIDAAIEEAKASTKPTLIIAK 246
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