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MAG: antitoxin, Phd family protein [Sedimenticola sp.]
type II toxin-antitoxin system Phd/YefM family antitoxin( domain architecture ID 10495655)
type II toxin-antitoxin (TA) system Phd/YefM family antitoxin is the antitoxin component of a TA module that binds to its cognate toxin and neutralizes its mRNA interferase activity and neutralizes its ability to phosphorylate host EF-Tu
List of domain hits
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Name | Accession | Description | Interval | E-value | ||
PhdYeFM_antitox | pfam02604 | Antitoxin Phd_YefM, type II toxin-antitoxin system; Members of this family act as antitoxins ... |
6-70 | 3.55e-11 | ||
Antitoxin Phd_YefM, type II toxin-antitoxin system; Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957. : Pssm-ID: 460615 Cd Length: 67 Bit Score: 53.42 E-value: 3.55e-11
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Name | Accession | Description | Interval | E-value | ||
PhdYeFM_antitox | pfam02604 | Antitoxin Phd_YefM, type II toxin-antitoxin system; Members of this family act as antitoxins ... |
6-70 | 3.55e-11 | ||
Antitoxin Phd_YefM, type II toxin-antitoxin system; Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957. Pssm-ID: 460615 Cd Length: 67 Bit Score: 53.42 E-value: 3.55e-11
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phd_fam | TIGR01552 | prevent-host-death family protein; This model recognizes a region of about 55 amino acids ... |
9-59 | 1.07e-06 | ||
prevent-host-death family protein; This model recognizes a region of about 55 amino acids toward the N-terminal end of bacterial proteins of about 85 amino acids in length. The best-characterized member is prevent-host-death (phd) of bacteriophage P1, the antidote partner of death-on-curing (doc) (TIGR01550) in an addiction module. Addiction modules prevent plasmid curing by killing the host cell as the longer-lived killing protein persists while the gene for the shorter-lived antidote is lost. Note, however, that relatively few members of this family appear to be plasmid or phage-encoded. Also, there is little overlap, except for phage P1 itself, of species with this family and with the doc family. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other] Pssm-ID: 273688 Cd Length: 52 Bit Score: 41.50 E-value: 1.07e-06
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StbD | COG2161 | Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ... |
9-76 | 6.80e-06 | ||
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms]; Pssm-ID: 441764 Cd Length: 83 Bit Score: 40.16 E-value: 6.80e-06
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Name | Accession | Description | Interval | E-value | ||
PhdYeFM_antitox | pfam02604 | Antitoxin Phd_YefM, type II toxin-antitoxin system; Members of this family act as antitoxins ... |
6-70 | 3.55e-11 | ||
Antitoxin Phd_YefM, type II toxin-antitoxin system; Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957. Pssm-ID: 460615 Cd Length: 67 Bit Score: 53.42 E-value: 3.55e-11
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phd_fam | TIGR01552 | prevent-host-death family protein; This model recognizes a region of about 55 amino acids ... |
9-59 | 1.07e-06 | ||
prevent-host-death family protein; This model recognizes a region of about 55 amino acids toward the N-terminal end of bacterial proteins of about 85 amino acids in length. The best-characterized member is prevent-host-death (phd) of bacteriophage P1, the antidote partner of death-on-curing (doc) (TIGR01550) in an addiction module. Addiction modules prevent plasmid curing by killing the host cell as the longer-lived killing protein persists while the gene for the shorter-lived antidote is lost. Note, however, that relatively few members of this family appear to be plasmid or phage-encoded. Also, there is little overlap, except for phage P1 itself, of species with this family and with the doc family. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other] Pssm-ID: 273688 Cd Length: 52 Bit Score: 41.50 E-value: 1.07e-06
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StbD | COG2161 | Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ... |
9-76 | 6.80e-06 | ||
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms]; Pssm-ID: 441764 Cd Length: 83 Bit Score: 40.16 E-value: 6.80e-06
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Blast search parameters | ||||
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