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Conserved domains on  [gi|1318842435|gb|AUJ87381|]
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sugar ABC transporter permease [Enterococcus sp. CR-Ec1]

Protein Classification

ABC transporter permease( domain architecture ID 10008345)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 3-316 1.81e-165

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 462.64  E-value: 1.81e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435   3 TAPIRQTVSVPKTKKQDIKMKIKKNRQLYLFVLPAFLIILIFSYGPMYGIIIAFKDYMPSLGILGSPWVGFKHFQRFFDS 82
Cdd:COG4209     2 STTAAKAKRKKKKRKKSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  83 YYFWELIKNTLGISIYSLVVGFPLPIILALALNEIKDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGIINHLLEF 162
Cdd:COG4209    82 PDFWRVLRNTLLISLLKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 163 LGFERISFMTNPRWFKTIYVLSGVWQGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMS 242
Cdd:COG4209   162 LGGEPINFLTEPKYFRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILN 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1318842435 243 FGSLMSVGFEKIILMQNPLNMQSSNVIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKRLSNSSL 316
Cdd:COG4209   242 IGNILNVGFEQIYLLYNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEESL 315
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 3-316 1.81e-165

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 462.64  E-value: 1.81e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435   3 TAPIRQTVSVPKTKKQDIKMKIKKNRQLYLFVLPAFLIILIFSYGPMYGIIIAFKDYMPSLGILGSPWVGFKHFQRFFDS 82
Cdd:COG4209     2 STTAAKAKRKKKKRKKSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  83 YYFWELIKNTLGISIYSLVVGFPLPIILALALNEIKDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGIINHLLEF 162
Cdd:COG4209    82 PDFWRVLRNTLLISLLKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 163 LGFERISFMTNPRWFKTIYVLSGVWQGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMS 242
Cdd:COG4209   162 LGGEPINFLTEPKYFRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILN 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1318842435 243 FGSLMSVGFEKIILMQNPLNMQSSNVIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKRLSNSSL 316
Cdd:COG4209   242 IGNILNVGFEQIYLLYNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEESL 315
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
32-303 4.05e-12

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 65.62  E-value: 4.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  32 LFVLPAFLIILIFSYGPMYGIIIAFKDYMPSLGiLGSPWVGFKHFQRFF-DSYY---FWELIKNTLGISIYSLVVGFPLP 107
Cdd:PRK10561    1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFG-FSSQFVGLDNFVALFhDSYYldsFWTTIKFSTLVTVSGLLVSLFFA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 108 IILALALNeikdgpFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGIINHLLEFLGFeRISFMTNPRWFKTIYVLSGVW 187
Cdd:PRK10561   80 ALVDYVVR------GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGY-DWNHAQNSGQAMFLVVFASVW 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 188 QGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFGSLMSVGFEKIILMQNPLNMQSSN 267
Cdd:PRK10561  153 KQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATT 232

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1318842435 268 VIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIV 303
Cdd:PRK10561  233 TLIYKIYREGFTGLDLSSSAAQSVVLMFLVIVLTVV 268
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 89-247 1.92e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 47.66  E-value: 1.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  89 IKNTLGISIYSLVVGFPLPIILALALNEiKDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGiinhlleflgferi 168
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILAR-KRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG-------------- 65

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1318842435 169 sFMTNPRWFKTIYVLSGVWQgTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFGSLM 247
Cdd:cd06261    66 -WGILPGLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARAL 142
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 103-312 3.27e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.91  E-value: 3.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 103 GFPLPIILALALNEIKDGPFKKITQTVTYAPNFIAVVVMVGmviaflspstgiinhlleflgferISFMTNPRWFKTIYV 182
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVV------------------------IAILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 183 LSGVWQGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFGSLM--SVGFEkIILMQNP 260
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALggAVLLE-FLGSWPG 135

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1318842435 261 LNMQSSNVIATFVYQQGlldaqYSFAAAVGLFNSLINSVLLIVVNHIAKRLS 312
Cdd:pfam00528 136 LGLLLIEAILGYDYPEI-----QGPVLAAALILLLLNLLVDILQRLLDPRVR 182
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 28-313 1.45e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 46.60  E-value: 1.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  28 RQLYLFVLPAFLIILIFSygPMYGIIIafKDYMPSLGilgsPWVGFKHFQRFFDSYYFWELIKNTLGISIYSLVVGFPLP 107
Cdd:TIGR03262   3 ARLLLAGMILALLLFLLL--PLLALLT--KSVYDSDG----DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 108 IILALALnEIKDGPFKKITQTVTYAPNFiAVVVMVGMVIAFLSPSTGIinhLLEFLGFErisfmtnprwfkTIYvlsGVW 187
Cdd:TIGR03262  75 FAFAYAL-TRSRIPGKGAFRLVALLPLL-APSLLPAISLIYLFGNQGL---LKGLLGGF------------SIY---GFW 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 188 qGTGWGSVIY---------LAALSGVDTQLHEAATIDGASRLQRVWYINIPT----IMPTMVILLIMSFGSLmsvGFEKI 254
Cdd:TIGR03262 135 -GIVIGEVFYtfphalmilVTALSLADGRLYEAARAMGASPWRTFFTVTLPGakygLISAAFVVFTLVITDF---GVPKV 210

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 255 IlmqnplnMQSSNVIATFVYQQGLLDAQYSFAAAVGLFnSLINSVL-LIVVNHIAKRLSN 313
Cdd:TIGR03262 211 I-------GGDYNVLATDIYKQVIGQQNFPMGAVVGVL-LLLPALLaFGIDRAIQRRQRA 262
 
Name Accession Description Interval E-value
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 3-316 1.81e-165

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 462.64  E-value: 1.81e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435   3 TAPIRQTVSVPKTKKQDIKMKIKKNRQLYLFVLPAFLIILIFSYGPMYGIIIAFKDYMPSLGILGSPWVGFKHFQRFFDS 82
Cdd:COG4209     2 STTAAKAKRKKKKRKKSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  83 YYFWELIKNTLGISIYSLVVGFPLPIILALALNEIKDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGIINHLLEF 162
Cdd:COG4209    82 PDFWRVLRNTLLISLLKLVFGFPLPIILALLLNELRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 163 LGFERISFMTNPRWFKTIYVLSGVWQGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMS 242
Cdd:COG4209   162 LGGEPINFLTEPKYFRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILN 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1318842435 243 FGSLMSVGFEKIILMQNPLNMQSSNVIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKRLSNSSL 316
Cdd:COG4209   242 IGNILNVGFEQIYLLYNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVGLFKSVVGLILVLIANKIAKKLGEESL 315
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
23-310 1.69e-59

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 192.27  E-value: 1.69e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  23 KIKKNRQLYLFVLPAFLIILIFSYGPM-YGIIIAFKDYmpSLGILGSPWVGFKHFQRFFDSYYFWELIKNTLGISIYSLV 101
Cdd:COG1175    13 RRRRRLAAYLFLLPALLLLLVFVLYPLlYTLYLSFTDW--NLLGPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVP 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 102 VGFPLPIILALALNeiKDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGIINHLLEFLGFERISFMTNPRWFKTIY 181
Cdd:COG1175    91 LQLVLGLLLALLLN--RKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAV 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 182 VLSGVWQGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSF-GSLMSvgFEKIILMQNP 260
Cdd:COG1175   169 IIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTiGALQV--FDLVYVLTGG 246

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1318842435 261 LNMQSSNVIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKR 310
Cdd:COG1175   247 GPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 21-310 1.05e-20

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 89.82  E-value: 1.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  21 KMKIKKNRQLYLFVLPAFLIILIFSYGPMYGII-IAFKDYMPSLGILGSPwvGFKHFQRFFDSYYFWELIKNTLGISIY- 98
Cdd:COG1176     2 SAALRRRLRPLLLLLPALLWLLLFFVLPLLLLLvYSFTTRDPYGGVVPGF--TLENYARLFTDPLYLKVLLRTLWIALLt 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  99 ---SLVVGFPLPIILALAlneikDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPsTGIINHLLEFLGF--ERISFMTN 173
Cdd:COG1176    80 tliCLLLGYPIAYFLARA-----PPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGR-NGLLNSLLLALGLidEPLRLLYT 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 174 PrwFKTIYVLsgVWqgtgwgsvIYL--------AALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFgs 245
Cdd:COG1176   154 E--FAVVIGL--VY--------VYLpfmvlplyAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVF-- 219

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1318842435 246 LMSVGFEKIILMqnpLNMQSSNVIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKR 310
Cdd:COG1176   220 IPALGAFVTPAL---LGGGKVLMIGNLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRR 281
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
22-316 1.30e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 74.04  E-value: 1.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  22 MKIKKNRQLYLFVLPAFLIILIFSYGPMYGIIIAfkdympslgilgSPWVGFKHFQRFFDSYYFWELIKNTLGISIYSLV 101
Cdd:COG1178     1 MSTRPRRRPRLLLLLLALLLALLVLLPLLALLLR------------AFTDGLANFWALLSDPYLWRALGNTLLLALLVTL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 102 VGFPLPIILALALnEIKDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPStGIINHLL-EFLGFERISfmtnprwfktI 180
Cdd:COG1178    69 LSLLLGVPLAWLL-ARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPN-GLLNTLLrALFGLEPPD----------I 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 181 YVLSGVW--QGTGWGSVIYL---AALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMV-------ILLIMSFGSLMS 248
Cdd:COG1178   137 YGLGGIIlvLVLFNYPYVYLllrAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAagallvfLLCLADFGTPLV 216

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1318842435 249 VGfekiilmqnplnmQSSNVIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKRLSNSSL 316
Cdd:COG1178   217 LG-------------GGYTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRRRYATV 271
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
32-303 4.05e-12

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 65.62  E-value: 4.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  32 LFVLPAFLIILIFSYGPMYGIIIAFKDYMPSLGiLGSPWVGFKHFQRFF-DSYY---FWELIKNTLGISIYSLVVGFPLP 107
Cdd:PRK10561    1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFG-FSSQFVGLDNFVALFhDSYYldsFWTTIKFSTLVTVSGLLVSLFFA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 108 IILALALNeikdgpFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGIINHLLEFLGFeRISFMTNPRWFKTIYVLSGVW 187
Cdd:PRK10561   80 ALVDYVVR------GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGY-DWNHAQNSGQAMFLVVFASVW 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 188 QGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFGSLMSVGFEKIILMQNPLNMQSSN 267
Cdd:PRK10561  153 KQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATT 232

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1318842435 268 VIATFVYQQGLLDAQYSFAAAVGLFNSLINSVLLIV 303
Cdd:PRK10561  233 TLIYKIYREGFTGLDLSSSAAQSVVLMFLVIVLTVV 268
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
23-310 1.44e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 58.63  E-value: 1.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  23 KIKKNRQLYLFVLPAFLIILIFSYGPMYGIIIAfkdympSLGILGSPWVGFKHFQRFFDSYYFWELIKNTLGISIYSLVV 102
Cdd:COG1178   280 RVKLGRWRWLALALCLLLVLLGLLLPLLALLLW------SLTKALDDNLTLDNYRFVLLDPSLLRALLNSLLLALLAALL 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 103 GFPLPIILALALnEIKDGPFKKITQTVTYAPNFI-AVVVMVGMVIAFLSPSTG---------IINHLLEFLGFerisfmt 172
Cdd:COG1178   354 AVLLALLLAYLV-RRRRGRLARLLDRLAMLPYAVpGIVLGLGLLLLFNRPLPLllygtlailVLAYVVRFLPF------- 425

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 173 nprwfktiyvlsgvwqgtgwGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFGSLM---SV 249
Cdd:COG1178   426 --------------------ALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMkelSA 485

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1318842435 250 gfekIILMQNPlnmqSSNVIATFVYQQgLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKR 310
Cdd:COG1178   486 ----TLLLRPP----GFETLAVLIYQL-ASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 26-243 2.54e-09

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 57.04  E-value: 2.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  26 KNRQLYLFVLPAFLIILIFSYGPM-YGIIIAFKDYmpslGILGSPWVGF--KHFQRFFDSYYFWELIKNTLGISIYSLVV 102
Cdd:COG1177     1 SSRLGRLLLRLFLALVLLFLYLPIlVLVLYSFNDS----WFLTFPPEGFtlRWYAELFSDPRLLDALLNSLLIALLSTLL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 103 GFPLPIILALALnEIKDGPFKKITQTVTYAPNFIAVVVM-VGMVIAF------LSPSTGIINHLLeflgferisfmtnpr 175
Cdd:COG1177    77 ATVLGTPAALAL-ARYRFRGRRLLLALLLLPLVVPGIVLgVALLLLFsalglsGGLWGLILAHVV--------------- 140

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1318842435 176 wFKTIYVLsgvwqgtgwgsVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSF 243
Cdd:COG1177   141 -FTLPFVV-----------LVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAF 196
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 89-247 1.92e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 47.66  E-value: 1.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  89 IKNTLGISIYSLVVGFPLPIILALALNEiKDGPFKKITQTVTYAPNFIAVVVMVGMVIAFLSPSTGiinhlleflgferi 168
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILAR-KRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG-------------- 65

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1318842435 169 sFMTNPRWFKTIYVLSGVWQgTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFGSLM 247
Cdd:cd06261    66 -WGILPGLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARAL 142
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 103-312 3.27e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.91  E-value: 3.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 103 GFPLPIILALALNEIKDGPFKKITQTVTYAPNFIAVVVMVGmviaflspstgiinhlleflgferISFMTNPRWFKTIYV 182
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVV------------------------IAILSILGHGILPAI 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 183 LSGVWQGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFGSLM--SVGFEkIILMQNP 260
Cdd:pfam00528  57 ILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALggAVLLE-FLGSWPG 135

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1318842435 261 LNMQSSNVIATFVYQQGlldaqYSFAAAVGLFNSLINSVLLIVVNHIAKRLS 312
Cdd:pfam00528 136 LGLLLIEAILGYDYPEI-----QGPVLAAALILLLLNLLVDILQRLLDPRVR 182
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 34-310 1.34e-05

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 45.90  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  34 VLPAFLIILIFSYGPMYGIIIafkdyMPSLGILGSPW-VGFKHFQRFFDSYYFWELIKNTLGISIYSLVVGFPLPIILAL 112
Cdd:COG0555     5 VLPGFGLTLGLTLLYLSLIVL-----LPLAALVLKAAgLGWAEFWAVLTSPRVLAALKLSLGTALIAALINLVFGLPLAW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 113 ALNEiKDGPFKKITQTVTYAPnfIAVVVMV-GMVIAFLSPSTGIINHLLEFLGFErISFmtnprwfktiyvlsgvwqgTG 191
Cdd:COG0555    80 VLVR-YRFPGKRLVDALVDLP--FALPTAVaGIALLLLFGPNGWLGQLLAPLGIK-VAF-------------------TP 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 192 WGSVIYL-------------AALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSFgsLMSVG-FEKIILM 257
Cdd:COG0555   137 LGIVLAQtfvslpfvvrtvqPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAF--ARALGeFGAVIFI 214

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1318842435 258 QNPLNMQsSNVIATFVYQQgLLDAQYSFAAAVGLFNSLINSVLLIVVNHIAKR 310
Cdd:COG0555   215 AGNLPMK-TEILPLLIYLK-LEEGDYAGATAIALVLLLISFLLLLLINLLQRR 265
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 28-313 1.45e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 46.60  E-value: 1.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  28 RQLYLFVLPAFLIILIFSygPMYGIIIafKDYMPSLGilgsPWVGFKHFQRFFDSYYFWELIKNTLGISIYSLVVGFPLP 107
Cdd:TIGR03262   3 ARLLLAGMILALLLFLLL--PLLALLT--KSVYDSDG----DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 108 IILALALnEIKDGPFKKITQTVTYAPNFiAVVVMVGMVIAFLSPSTGIinhLLEFLGFErisfmtnprwfkTIYvlsGVW 187
Cdd:TIGR03262  75 FAFAYAL-TRSRIPGKGAFRLVALLPLL-APSLLPAISLIYLFGNQGL---LKGLLGGF------------SIY---GFW 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 188 qGTGWGSVIY---------LAALSGVDTQLHEAATIDGASRLQRVWYINIPT----IMPTMVILLIMSFGSLmsvGFEKI 254
Cdd:TIGR03262 135 -GIVIGEVFYtfphalmilVTALSLADGRLYEAARAMGASPWRTFFTVTLPGakygLISAAFVVFTLVITDF---GVPKV 210

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 255 IlmqnplnMQSSNVIATFVYQQGLLDAQYSFAAAVGLFnSLINSVL-LIVVNHIAKRLSN 313
Cdd:TIGR03262 211 I-------GGDYNVLATDIYKQVIGQQNFPMGAVVGVL-LLLPALLaFGIDRAIQRRQRA 262
malF PRK10999
maltose ABC transporter permease MalF;
131-243 1.38e-04

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 43.41  E-value: 1.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 131 YA-PNFIAVVVMVGMviafLSPSTGIINHLLEFLgferisFMTNPRWF------KTIYVLSGVWQGTGWGSVIYLAALSG 203
Cdd:PRK10999  331 YAvPSFISILIFKGL----FNQSFGEINMMLSAL------FGIKPAWFsdptlaKTMILIVNTWLGYPYMMILCMGLLKA 400

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1318842435 204 VDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSF 243
Cdd:PRK10999  401 IPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASF 440
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 30-243 7.44e-04

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 40.46  E-value: 7.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  30 LYLFVLPAFLIILIfsygPMYGIII-AFKD----YMPSLGILGSPWvGFKHFQRFFDSYYFWELIKNTLGISIYSLVVGF 104
Cdd:COG0395    17 LYLLLILLALLFLF----PLYWMVVtSFKPpaeiFSGPPSLLPSEF-TLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435 105 PLPIILALALnEIKDGPFKkitqtvtyapNFIAVVVMVGMVI---AFLSPSTGIINHLleflgferisfmtnpRWFKTI- 180
Cdd:COG0395    92 LLSSLAAYAL-ARFRFRGR----------KLLFLLILATLMIpgqVLLIPLYLLFRQL---------------GLLNTYw 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1318842435 181 -YVLSGVWQGTGWGSVIYLAALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSF 243
Cdd:COG0395   146 gLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTF 209
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 21-243 7.49e-04

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 40.52  E-value: 7.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  21 KMKIKKNRQLYLFVLPAFLIIL-IFSYGPMYGIIIA-FK--DYMPSLGILGSPWvGFKHFQRFFDSYYFWELIKNTLGIS 96
Cdd:COG3833     4 RKSRKRRRRLKLGLRHLVLIILaIIALFPILWVVSAsFNpgGSLYSSSLIPENF-TLENYKKLFTETPFLRWFLNSLIVA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1318842435  97 IYSLVVGFPLPIILALALNEIKdGPFKK-------ITQTVtyaPNFIAVVVMVGMVIAFlspstGIINHLLeflgferis 169
Cdd:COG3833    83 VVTAIISVFLAALAAYAFSRFR-FKGRKagllallLLQMF---PAFLALVALYLLLSAL-----GLLNTLL--------- 144

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1318842435 170 fmtnprwfktiyVLSGVWQGTGWGSVIYLA--ALSGVDTQLHEAATIDGASRLQRVWYINIPTIMPTMVILLIMSF 243
Cdd:COG3833   145 ------------GLILVYLGGAIPFNTWLMkgYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSF 208
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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