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Conserved domains on  [gi|13124752|sp|Q02985|]
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RecName: Full=Complement factor H-related protein 3; Short=FHR-3; AltName: Full=DOWN16; AltName: Full=H factor-like protein 3; Flags: Precursor

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 107-329 2.20e-18

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 83.16  E-value: 2.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  107 GNSTEVACHPGYGLPK-AQTTVTCTEKGWSPTPRCIRVRTCSKSDIEieNGFISESSSIYilNKEIQYKCKPGY------ 179
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRDID--NGQLDIGGVDF--GSSITYSCNSGYqliges 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  180 -ATADGNSSGSITclqngWSAQ-PICinSSEKCGPPPPISNGDTTSFLlKVYVPQSRVEYQCQPYYELQGSNYVTCSNGE 257
Cdd:PHA02927 123 kSYCELGSTGSMV-----WNPEaPIC--ESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE 194

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13124752  258 WSEPP-----RCIHPCIiteenmnkNNIKLKGRSDRKYyaKTGDTIEFMCKLGYNANTSILSFQAVCREGIVEYPRC 329
Cdd:PHA02927 195 WSDPPtcqivKCPHPTI--------SNGYLSSGFKRSY--SYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
PHA02954 super family cl31523
EEV membrane glycoprotein; Provisional
 13-142 7.75e-07

EEV membrane glycoprotein; Provisional


The actual alignment was detected with superfamily member PHA02954:

Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 50.08  E-value: 7.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752   13 VSCANGQVKPCDfpdIKHGGLfhENMRRPYfpvAVGKYYSYYCDEHFETPSGSYwdyIHCTQNGWSPAVPCLRKCYFPYL 92
Cdd:PHA02954 123 VTCPNAECQPLQ---LEHGSC--QPVKEKY---SFGEHITINCDVGYEVIGASY---ISCTANSWNVIPSCQQKCDIPSL 191

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 13124752   93 ENGYNQnyGRKFVQGNSTEVACHPGYGLPKAQTTvTCTEKGWSPT-PRCIR 142
Cdd:PHA02954 192 SNGLIS--GSTFSIGGVIHLSCKSGFTLTGSPSS-TCIDGKWNPVlPICVR 239
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 107-329 2.20e-18

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 83.16  E-value: 2.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  107 GNSTEVACHPGYGLPK-AQTTVTCTEKGWSPTPRCIRVRTCSKSDIEieNGFISESSSIYilNKEIQYKCKPGY------ 179
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRDID--NGQLDIGGVDF--GSSITYSCNSGYqliges 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  180 -ATADGNSSGSITclqngWSAQ-PICinSSEKCGPPPPISNGDTTSFLlKVYVPQSRVEYQCQPYYELQGSNYVTCSNGE 257
Cdd:PHA02927 123 kSYCELGSTGSMV-----WNPEaPIC--ESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE 194

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13124752  258 WSEPP-----RCIHPCIiteenmnkNNIKLKGRSDRKYyaKTGDTIEFMCKLGYNANTSILSFQAVCREGIVEYPRC 329
Cdd:PHA02927 195 WSDPPtcqivKCPHPTI--------SNGYLSSGFKRSY--SYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 210-265 1.08e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.32  E-value: 1.08e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 13124752 210 CGPPPPISNGDTTSFLlKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRCI 265
Cdd:cd00033   1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
210-264 6.39e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 6.39e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 13124752   210 CGPPPPISNGDTTSfLLKVYVPQSRVEYQCQPYYELQGSNYVTCS-NGEWS-EPPRC 264
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 210-264 1.61e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 1.61e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 13124752    210 CGPPPPISNGDTTSFLlKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRC 264
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 13-142 7.75e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 50.08  E-value: 7.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752   13 VSCANGQVKPCDfpdIKHGGLfhENMRRPYfpvAVGKYYSYYCDEHFETPSGSYwdyIHCTQNGWSPAVPCLRKCYFPYL 92
Cdd:PHA02954 123 VTCPNAECQPLQ---LEHGSC--QPVKEKY---SFGEHITINCDVGYEVIGASY---ISCTANSWNVIPSCQQKCDIPSL 191

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 13124752   93 ENGYNQnyGRKFVQGNSTEVACHPGYGLPKAQTTvTCTEKGWSPT-PRCIR 142
Cdd:PHA02954 192 SNGLIS--GSTFSIGGVIHLSCKSGFTLTGSPSS-TCIDGKWNPVlPICVR 239
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 107-329 2.20e-18

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 83.16  E-value: 2.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  107 GNSTEVACHPGYGLPK-AQTTVTCTEKGWSPTPRCIRVRTCSKSDIEieNGFISESSSIYilNKEIQYKCKPGY------ 179
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRDID--NGQLDIGGVDF--GSSITYSCNSGYqliges 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  180 -ATADGNSSGSITclqngWSAQ-PICinSSEKCGPPPPISNGDTTSFLlKVYVPQSRVEYQCQPYYELQGSNYVTCSNGE 257
Cdd:PHA02927 123 kSYCELGSTGSMV-----WNPEaPIC--ESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE 194

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13124752  258 WSEPP-----RCIHPCIiteenmnkNNIKLKGRSDRKYyaKTGDTIEFMCKLGYNANTSILSFQAVCREGIVEYPRC 329
Cdd:PHA02927 195 WSDPPtcqivKCPHPTI--------SNGYLSSGFKRSY--SYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 69-265 1.55e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 69.68  E-value: 1.55e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752   69 YIHCTQNGWSPAVPCL-RKCYFPY-LENGYNQNYGRKFvqGNSTEVACHPGY---GLPKAQTTVTCT-EKGWSP-TPRCI 141
Cdd:PHA02927  67 YAKCTGTGWTLFNQCIkRRCPSPRdIDNGQLDIGGVDF--GSSITYSCNSGYqliGESKSYCELGSTgSMVWNPeAPICE 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  142 RVRtcSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATAdGNSsgSITCLQNGWSAQPICinSSEKCgPPPPISNGDT 221
Cdd:PHA02927 145 SVK--CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI-GNS--GVLCSGGEWSDPPTC--QIVKC-PHPTISNGYL 216

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 13124752  222 TSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSEP--PRCI 265
Cdd:PHA02927 217 SSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 210-265 1.08e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.32  E-value: 1.08e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 13124752 210 CGPPPPISNGDTTSFLlKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRCI 265
Cdd:cd00033   1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
210-264 6.39e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 6.39e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 13124752   210 CGPPPPISNGDTTSfLLKVYVPQSRVEYQCQPYYELQGSNYVTCS-NGEWS-EPPRC 264
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 210-264 1.61e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 1.61e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 13124752    210 CGPPPPISNGDTTSFLlKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRC 264
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 13-142 7.75e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 50.08  E-value: 7.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752   13 VSCANGQVKPCDfpdIKHGGLfhENMRRPYfpvAVGKYYSYYCDEHFETPSGSYwdyIHCTQNGWSPAVPCLRKCYFPYL 92
Cdd:PHA02954 123 VTCPNAECQPLQ---LEHGSC--QPVKEKY---SFGEHITINCDVGYEVIGASY---ISCTANSWNVIPSCQQKCDIPSL 191

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 13124752   93 ENGYNQnyGRKFVQGNSTEVACHPGYGLPKAQTTvTCTEKGWSPT-PRCIR 142
Cdd:PHA02954 192 SNGLIS--GSTFSIGGVIHLSCKSGFTLTGSPSS-TCIDGKWNPVlPICVR 239
PHA02639 PHA02639
EEV host range protein; Provisional
 146-307 1.86e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 48.89  E-value: 1.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  146 CSKSDiEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQ-PICInsSEKCGPPPPISNGDTTS 223
Cdd:PHA02639  22 CDKPD-DISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAiWSNKaPFCM--LKECNDPPSIINGKIYN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  224 fLLKVYVPQSRVEYQCQPY----YELQGSNYVTCS-NGEWS-EPPRC--IHPCIITEENMNKNNIKlkgrSDRKYYAKTg 295
Cdd:PHA02639  99 -KREMYKVGDEIYYVCNEHkgvqYSLVGNEKITCIqDKSWKpDPPICkmINCRFPALQNGYINGIP----SNKKFYYKT- 172

                        170
                 ....*....|..
gi 13124752  296 dTIEFMCKLGYN 307
Cdd:PHA02639 173 -RVGFSCKSGFD 183
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 45-204 1.90e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 48.50  E-value: 1.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752   45 VAVGKYYSYYCDEHFETpSGSYWDYIHCTQNG---WSPAVPCLR--KCYFP-YLENGYNQNYGRKFVQGNSTEVACHPGY 118
Cdd:PHA02927 102 VDFGSSITYSCNSGYQL-IGESKSYCELGSTGsmvWNPEAPICEsvKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGY 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  119 GLpKAQTTVTCTEKGWSPTPRCIRVRTCSKSdieIENGFISES-SSIYILNKEIQYKCKPGYATAdgNSSGSITCLQNGW 197
Cdd:PHA02927 181 SL-IGNSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGfKRSYSYNDNVDFKCKYGYKLS--GSSSSTCSPGNTW 254


                 ....*...
gi 13124752  198 SAQ-PICI 204
Cdd:PHA02927 255 QPElPKCV 262
PHA02831 PHA02831
EEV host range protein; Provisional
 145-327 9.67e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.52  E-value: 9.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  145 TCSKSDIEIENgFISESSSIYILNKEIQYKCKPGYatadgnSSGSITCLQNGWSAQPICINSSeKCGPPPPISNGDTTSF 224
Cdd:PHA02831  21 VFNKNDAKYSN-VDSYENKVYEENENLEYKCNNNF------DKVFVTCNNGSWSTKNMCIGKR-NCKDPVTILNGYIKNK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  225 LLKvYVPQSRVEYQCQ----PYYELQGSNYVTCSNGEW-SEPP-----RCIHPCIiteenmnkNNIKLKGRSDRKYYakt 294
Cdd:PHA02831  93 KDQ-YSFGDSVTYACKvnklEKYSIVGNETVKCINKQWvPKYPvckliRCKYPAL--------QNGFLNVFEKKFYY--- 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 13124752  295 GDTIEFMCKLGYNANTSILSfqaVCREGIVEYP 327
Cdd:PHA02831 161 GDIVNFKCKKGFILLGSSVS---TCDINSIWYP 190
PHA02831 PHA02831
EEV host range protein; Provisional
 127-265 1.10e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 43.06  E-value: 1.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  127 VTCTEKGWSPTPRCIRVRTCsKSDIEIENGFISESSSIYILNKEIQYKCKPG----YATAdGNSsgSITCLQNGWSAQ-P 201
Cdd:PHA02831  59 VTCNNGSWSTKNMCIGKRNC-KDPVTILNGYIKNKKDQYSFGDSVTYACKVNklekYSIV-GNE--TVKCINKQWVPKyP 134

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 13124752  202 ICinSSEKCgPPPPISNGDTTSFLLKVYVPQSrVEYQCQPYYELQGSNYVTCS-NGEW-SEPPRCI 265
Cdd:PHA02831 135 VC--KLIRC-KYPALQNGFLNVFEKKFYYGDI-VNFKCKKGFILLGSSVSTCDiNSIWyPGIPKCV 196
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 152-204 1.22e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.37  E-value: 1.22e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 13124752 152 EIENGFISESSSIYILNKEIQYKCKPGYATadgNSSGSITCLQNG-WS-AQPICI 204
Cdd:cd00033   6 VPENGTVTGSKGSYSYGSTVTYSCNEGYTL---VGSSTITCTENGgWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 152-203 3.24e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.28  E-value: 3.24e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 13124752    152 EIENGFISESSSIYILNKEIQYKCKPGYATadgNSSGSITCLQNG-WS-AQPIC 203
Cdd:smart00032   6 DIENGTVTSSSGTYSYGDTVTYSCDPGYTL---IGSSTITCLENGtWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 20-142 1.64e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 39.65  E-value: 1.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752   20 VKPC-DFPDIKHGGLFheNMRRPYfpvAVGKYYSYYCDEHfetpSGSYW-----DYIHCTQN-GWSPAVPCLR--KCYFP 90
Cdd:PHA02639  82 LKECnDPPSIINGKIY--NKREMY---KVGDEIYYVCNEH----KGVQYslvgnEKITCIQDkSWKPDPPICKmiNCRFP 152

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 13124752   91 YLENGYNQNY--GRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPT-PRCIR 142
Cdd:PHA02639 153 ALQNGYINGIpsNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSiPTCVR 207
PHA02831 PHA02831
EEV host range protein; Provisional
 70-142 2.57e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 38.82  E-value: 2.57e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 13124752   70 IHCTQNGWSPAVPC--LRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPT-PRCIR 142
Cdd:PHA02831 122 VKCINKQWVPKYPVckLIRCKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGiPKCVK 197
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 87-141 3.02e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 35.52  E-value: 3.02e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 13124752  87 CYFPY-LENGYNQNYGRKFVQGNSTEVACHPGYGLpKAQTTVTCTEKG-WSPT-PRCI 141
Cdd:cd00033   1 CPPPPvPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTENGgWSPPpPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 1-162 4.14e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 38.00  E-value: 4.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752    1 MLLLINVILtlwvsCANGQVKPCDFPDIKHGGLFheNMRRPYfpvAVGKYYSYYCDEHFETPSGSYW--DYIHCTQNG-W 77
Cdd:PHA02817   8 LILLCNKVY-----SLCDLNKCCYPPSIKNGYIY--NKKTEY---NIGSNVTFFCGNNTRGVRYTLVgeKNIICEKDGkW 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752   78 SPAVPCLR--KCYFPYLENGYNQNY--GRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPtprciRVRTCSKSDIEI 153
Cdd:PHA02817  78 NKEFPVCKiiRCRFPALQNGFVNGIpdSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIP-----KVPICSRDNITY 152


                 ....*....
gi 13124752  154 ENGFISESS 162
Cdd:PHA02817 153 NKIYINKVN 161
PHA02831 PHA02831
EEV host range protein; Provisional
 223-330 4.18e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 38.43  E-value: 4.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13124752  223 SFLLKVYVPQSRVEYQCQPYYElqgSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNiKLKGRSDRKYYaktGDTIEFMC 302
Cdd:PHA02831  34 SYENKVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIGKRNCKDPVTILNG-YIKNKKDQYSF---GDSVTYAC 106

                         90       100       110
                 ....*....|....*....|....*....|.
gi 13124752  303 KLGYNANTSILSFQAV-CREG--IVEYPRCE 330
Cdd:PHA02831 107 KVNKLEKYSIVGNETVkCINKqwVPKYPVCK 137
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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