ATP synthase subunit C;

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                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1309179976 26 IAAGASMSVSALAAGYAQAKIGSAGAGTLAERPEVATNIIVLQALPEIIALLGFVIAFMI 85
Cdd:pfam00137  1 LGAGLAVGLAALGSGIGQGIAGAAAIEAIARQPKLFGKMLIGAALAEALAIYGLVVALLL 60

Membrane-bound Vo/Ao complexes of V/A-type ATP synthases, subunit c; Vo/Ao-ATP synthase subunit c. The V- and A-type family of ATPases are composed of two linked multi-subunit complexes: the V1 and A1 complexes contain three copies each of the alpha and beta subunits that form the soluble catalytic core, which is involved in ATP synthesis/hydrolysis, and the Vo or Ao complex that forms the membrane-embedded proton pore. The A-ATP synthase (AoA1-ATPases) is exclusively found in archaea and functions like the F-ATP synthase. Structurally, however, the A-ATP synthase is more closely related to the V-ATP synthase (vacuolar VoV1-ATPase), which is a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. The V- and A-type synthases can function in both ATP synthesis and hydrolysis modes. The V1 complex consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The Vo complex consists of five different subunits: a, c, c', c'', and d. The Ao/A1 complexes are composed of nine subunits in a stoichiometry of A(3):B(3):C:D:E:F:H(2):a:c(x). ATP is synthesized on the A3:B3 hexamer and the energy released during that process is transferred to the Ao complex, which consists of the C-terminal segment of subunit a and subunit c.

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                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1309179976 24 KAIAAGASMSVSALAAGYAQAKIGSAGAGTLAERPEVATNIIVLQALPEIIALLGFVIAFMI 85
Cdd:cd18120    1 AYLGAALAVGLSCLGAGIAVGMVGAAAIGAIAEKPELFGKALIFVGLAEGLAIYGLIVAILI 62

V-type sodium ATPase subunit K (NTPK) and similar proteins; NTPK (also called Na(+)-translocating ATPase subunit K, or sodium ATPase proteolipid component) is involved in ATP-driven sodium extrusion.

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                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1309179976 25 AIAAGASMSVSALAAGYAQAKIGSAGAGTLAERPEVATNIIVLQALPEIIALLGFVIAFMI 85
Cdd:cd18180    4 ILGAGLPVGIVGLFSAIYQGKVAAAGIGAVAKRPEEFGKAIILAAMVETYAILGLLISILI 64

ATP synthase, membrane-bound Fo/Vo/Ao complexes, subunit c; Subunit c of the Fo/Vo/Ao complex is the main transmembrane subunit of F-, V- or A-type family of ATP synthases with rotary motors. These ion-transporting rotary ATP synthases are composed of two linked multi-subunit complexes: the F1, V1, and A1 complexes contains three copies each of the alpha and beta subunits that form the soluble catalytic core, which is involved in ATP synthesis/hydrolysis, and the Fo, Vo, or Ao (oligomycin sensitive) complex that forms the membrane-embedded proton pore. The F-ATP synthases (also called FoF1-ATPases) are found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts, or in the plasma membranes of bacteria. F-ATPases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. The A-ATP synthase (AoA1-ATPases) is exclusively found in archaea and function like F-ATP synthase. Structurally, however, the A-ATP synthase is more closely related to the V-ATP synthase (vacuolar VoV1-ATPase), which is a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. Collectively, F-, V-, and A-type synthases can function in both ATP synthesis and hydrolysis modes.

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                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1309179976 25 AIAAGASMSVSALAAGYAQAKIGSAGAGTLAERPEVA----TNIIVLQALPEIIALLGFVIAFMI 85
Cdd:cd00313    1 ALGAGLAIGLAAIGAGIGIGLAGAAALEAIARQPEAAgkifTTMLIGLALIESLAIYGLVIAFLL 65

V-type ATP synthase subunit K; Validated

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                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1309179976  26 IAAGASMSVSALAAGYAQAKIGSAGAGTLAERPEVATNIIVLQALPEIIALLGFVIAFM 84
Cdd:PRK06558   95 FAACLPIAIVGLFSAISQGKVAAAGIQILAKRPEEFTKGIILAAMVETYAILAFVVSFL 153