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Conserved domains on  [gi|1308963981|gb|PKO73953|]
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type IV pilus secretin PilQ, partial [Betaproteobacteria bacterium HGW-Betaproteobacteria-17]

Protein Classification

type IV pilus secretin family protein( domain architecture ID 13775220)

type IV pilus secretin family protein such as PilQ, which is required for type IV pilus biogenesis and competence, and could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 71-665 0e+00

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 735.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981  71 SVEYEAQIDGKTLLVALGDVGVGVGTApvnvSPRFAEAAPgAARHSIRDIDFRRGAAGEARIVTTLSDAQAGINIRQQAG 150
Cdd:COG4796     1 PVPYETRVEGNALLVTLGPAAAAAAAA----AAAFAEAAA-AAANAIRDIDFRRGEDGEGRVVVDLSDPGVGVDIRQQGG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 151 GVVVDFIGTELPKALQRRLDVADFGTPVQIVETYTLGDNTRMVIQPKGGWEYSAYQTDNSFIVEVKQ-SDDGQKKTADGK 229
Cdd:COG4796    76 KLVVDFLNTSLPEELRRRLDVTDFATPVQSIDAFQQGDNVRLVIEPRGDWEYSAYQTDNQFVVEVKPlTEDENKLAQGGK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 230 VKYVGEKLSLNFQNVEVRSVLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKDE 309
Cdd:COG4796   156 KGYTGEKLSLNFQDIPVRSVLQLIADFTGLNLVISDSVTGNITLRLKNVPWDQALDIILKAKGLDKRKNGNVLLVAPAEE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 310 LMAKEKLEYEARSAVADLEPLTTEYIQLNYMRADEAQTMLYGfasgaflasagnnavncsaqaqglgggaaaqasqqgqg 389
Cdd:COG4796   236 LAAREKLELEAKQQIEELEPLRTEYIQLNYAKASDLAKLLKG-------------------------------------- 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 390 eNDQKVLTKRGRATYELKTNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAANSSGSR 469
Cdd:COG4796   278 -QRGSLLSERGSVTVDERTNTLIVRDTPSKLEEIRRLIAKLDIPVRQVLIEARIVEASDSFSRELGVRWGGSGANGTGNN 356

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 470 SISG------GGQALPSVLPNLVMNL-------------LDPANGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVIL 530
Cdd:COG4796   357 RGGIggslngTTAGTPLLPDGLNVNLpaanpagslgltlAKLGGGRLLDLELSALEAEGKGEIISSPRVITADQQEASIE 436

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 531 NGTQIPYITpGTANTPATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAVRFISGISDPAIDTKRIKTQVRVNNGETLV 610
Cdd:COG4796   437 QGTEIPYQE-SSSSGATSVEFKEAVLSLEVTPQITPDGRIILDLDVSKDSPGETVAGGVPAIDTKEIKTQVLVENGETVV 515

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1308963981 611 LGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRILDERLS 665
Cdd:COG4796   516 LGGIYEQTESNSVDKVPFLGDIPLLGWLFKNTTKTDEKRELLIFITPRIVKDALA 570
AMIN pfam11741
AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the ...
 4-87 2.75e-10

AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localizes to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localization of periplasmic protein complexes.


:

Pssm-ID: 463338  Cd Length: 96  Bit Score: 57.31  E-value: 2.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981   4 VRVTLKNALTATPAGFTVGNPPRIALDLPDTGNAMGRNTVEANLGPLSSVNVVQ-AGTRTRLVLNLNKSVEYEAQI--DG 80
Cdd:pfam11741  10 TELELETSGGEKYQVFTLSNPNRLVIDIPGAQLGLPLKRIENPSPGIKSVRVGQfDPNTVRVVVDLDGSVLPQVPVfkSG 89


                  ....*..
gi 1308963981  81 KTLLVAL 87
Cdd:pfam11741  90 EGLVVDL 96
 
Name Accession Description Interval E-value
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 71-665 0e+00

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 735.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981  71 SVEYEAQIDGKTLLVALGDVGVGVGTApvnvSPRFAEAAPgAARHSIRDIDFRRGAAGEARIVTTLSDAQAGINIRQQAG 150
Cdd:COG4796     1 PVPYETRVEGNALLVTLGPAAAAAAAA----AAAFAEAAA-AAANAIRDIDFRRGEDGEGRVVVDLSDPGVGVDIRQQGG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 151 GVVVDFIGTELPKALQRRLDVADFGTPVQIVETYTLGDNTRMVIQPKGGWEYSAYQTDNSFIVEVKQ-SDDGQKKTADGK 229
Cdd:COG4796    76 KLVVDFLNTSLPEELRRRLDVTDFATPVQSIDAFQQGDNVRLVIEPRGDWEYSAYQTDNQFVVEVKPlTEDENKLAQGGK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 230 VKYVGEKLSLNFQNVEVRSVLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKDE 309
Cdd:COG4796   156 KGYTGEKLSLNFQDIPVRSVLQLIADFTGLNLVISDSVTGNITLRLKNVPWDQALDIILKAKGLDKRKNGNVLLVAPAEE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 310 LMAKEKLEYEARSAVADLEPLTTEYIQLNYMRADEAQTMLYGfasgaflasagnnavncsaqaqglgggaaaqasqqgqg 389
Cdd:COG4796   236 LAAREKLELEAKQQIEELEPLRTEYIQLNYAKASDLAKLLKG-------------------------------------- 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 390 eNDQKVLTKRGRATYELKTNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAANSSGSR 469
Cdd:COG4796   278 -QRGSLLSERGSVTVDERTNTLIVRDTPSKLEEIRRLIAKLDIPVRQVLIEARIVEASDSFSRELGVRWGGSGANGTGNN 356

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 470 SISG------GGQALPSVLPNLVMNL-------------LDPANGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVIL 530
Cdd:COG4796   357 RGGIggslngTTAGTPLLPDGLNVNLpaanpagslgltlAKLGGGRLLDLELSALEAEGKGEIISSPRVITADQQEASIE 436

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 531 NGTQIPYITpGTANTPATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAVRFISGISDPAIDTKRIKTQVRVNNGETLV 610
Cdd:COG4796   437 QGTEIPYQE-SSSSGATSVEFKEAVLSLEVTPQITPDGRIILDLDVSKDSPGETVAGGVPAIDTKEIKTQVLVENGETVV 515

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1308963981 611 LGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRILDERLS 665
Cdd:COG4796   516 LGGIYEQTESNSVDKVPFLGDIPLLGWLFKNTTKTDEKRELLIFITPRIVKDALA 570
IV_pilus_PilQ TIGR02515
type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ ...
 234-661 4.00e-156

type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures]


Pssm-ID: 274173 [Multi-domain]  Cd Length: 418  Bit Score: 456.78  E-value: 4.00e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 234 GEKLSLNFQNVEVRSVLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKDELMAK 313
Cdd:TIGR02515   1 GEKISLNFQDIPVRTVLQVIAEFTGLNIVVSDSVQGNITLRLKNVPWDQALDIVLKSKGLDKRRDGNIIYIAPLDELAAQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 314 EKLEYEARSAVADLEPLTTEYIQLNYMRADEAQTMLYGFASGAflasagnnavncsaqaqglgggaaaqasqqgqgendQ 393
Cdd:TIGR02515  81 EKDELEAKKQIENLEPLQTELIQLNYAKASDIAKVLTGVTGGS------------------------------------G 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 394 KVLTKRGRATYELKTNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAA---------- 463
Cdd:TIGR02515 125 GLLSPRGSVTVDPRTNTLIVTDTPENLARIRKLIAELDIPVRQVLIEARIVEATDSFSRELGVRWGITDKngngngtagg 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 464 --NSSGSRSISGGGQALPSVLPNLVMNLLDPA-------------NGSLLNLELRALEADSKGKVISNPRVMTTNQKPAV 528
Cdd:TIGR02515 205 igGNNGTTATGAGGTGNPPFGDNLNVNLATATtaagisfalgkigSGRLLDLELSALESEGKGEIISSPRVLTANNKEAK 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 529 ILNGTQIPYITpGTANTPATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAVRFIS--GISDPAIDTKRIKTQVRVNNG 606
Cdd:TIGR02515 285 IEQGTEIPYQQ-TSSSGATSVEFKEAVLSLEVTPQITPDGRIIMDLLVSKDSPGVVAqaGGGVPAIDKQEINTQVLVKNG 363

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1308963981 607 ETLVLGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRILD 661
Cdd:TIGR02515 364 ETVVIGGIYEQTQTNSEDKVPLLGDIPVLGNLFKKTGKSDEKSELLIFITPRIVN 418
hofQ PRK13568
DNA uptake porin HofQ;
249-660 2.29e-78

DNA uptake porin HofQ;


Pssm-ID: 237430 [Multi-domain]  Cd Length: 381  Bit Score: 254.66  E-value: 2.29e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 249 VLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKDELMAKEKLEYEARSAVADLE 328
Cdd:PRK13568    1 VLQALADYQQLNLVTAPGVGGNLSLRLIEVPWEQALAIILRMGKLSAEREGNVLMVFPEQEIQERQQKTKQQAAPQEQML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 329 PLTTEYIQLNYMRADEAQTMLYgfASGAFLasagnnavncsaqaqglgggaaaqasqqgqgendqkvLTKRGRATYELKT 408
Cdd:PRK13568   81 PLANLTLTLQYADAEEVADSLQ--SQRGGL-------------------------------------LSPRGSVTADKRT 121

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 409 NTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAANSSGsrsisgggQALPSVLPNLVMN 488
Cdd:PRK13568  122 NTLLIRDTPAALAQLKNWLIELDLPLQQVQLAAHIVTISSESLQELGVRWGMGEGKQGN--------TALRINDFNVNLP 193

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 489 LLDPA----------NGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYITPGTANTPATVTFKDAFLCL 558
Cdd:PRK13568  194 LPNPAasagfhlarlGGRLLDLELSALEQENQVDIIASPRLFTSHQQTASIKQGTEIPYTVSSGKSGSTSIEFKEAVLGM 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 559 LVDPQILNNDSVILTVEVQKD----AVRfiSGISDP-AIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGDIP 633
Cdd:PRK13568  274 EVTPKILRNGRITLKLKISQNmpgrTIK--RGEGEMlAIDKQEIQTQVTVKDGETIVLGGIFQQQKRQSVNKVPLLGDIP 351

                         410       420
                  ....*....|....*....|....*..
gi 1308963981 634 GLGHLFKTTIKENSKTELIIFLTPRIL 660
Cdd:PRK13568  352 LLGALFRQDTQQQSRRELVIFITPKLI 378
Secretin pfam00263
Bacterial type II and III secretion system protein;
504-660 3.68e-56

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 187.73  E-value: 3.68e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 504 ALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYITPGTANTP--ATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAV 581
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTttTTVEFKDAGLSLKVTPQVTPDGTITLKINPEVSSP 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1308963981 582 RFISGISDPAIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRIL 660
Cdd:pfam00263  81 DGNGGNGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIFITPRIV 159
AMIN pfam11741
AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the ...
 4-87 2.75e-10

AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localizes to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localization of periplasmic protein complexes.


Pssm-ID: 463338  Cd Length: 96  Bit Score: 57.31  E-value: 2.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981   4 VRVTLKNALTATPAGFTVGNPPRIALDLPDTGNAMGRNTVEANLGPLSSVNVVQ-AGTRTRLVLNLNKSVEYEAQI--DG 80
Cdd:pfam11741  10 TELELETSGGEKYQVFTLSNPNRLVIDIPGAQLGLPLKRIENPSPGIKSVRVGQfDPNTVRVVVDLDGSVLPQVPVfkSG 89


                  ....*..
gi 1308963981  81 KTLLVAL 87
Cdd:pfam11741  90 EGLVVDL 96
STN smart00965
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 259-307 1.09e-05

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 198033 [Multi-domain]  Cd Length: 52  Bit Score: 42.88  E-value: 1.09e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1308963981  259 LNIIASD--TVSGNLTLRLKDVPWDQALDLIMQTKGLD-KRQNGNVIWIAPK 307
Cdd:smart00965   1 LNFVYDPalVAGRRVSLLLGNVTVEQALDRLLAGTGLTyRRIGGNTIVLSPA 52
 
Name Accession Description Interval E-value
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 71-665 0e+00

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 735.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981  71 SVEYEAQIDGKTLLVALGDVGVGVGTApvnvSPRFAEAAPgAARHSIRDIDFRRGAAGEARIVTTLSDAQAGINIRQQAG 150
Cdd:COG4796     1 PVPYETRVEGNALLVTLGPAAAAAAAA----AAAFAEAAA-AAANAIRDIDFRRGEDGEGRVVVDLSDPGVGVDIRQQGG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 151 GVVVDFIGTELPKALQRRLDVADFGTPVQIVETYTLGDNTRMVIQPKGGWEYSAYQTDNSFIVEVKQ-SDDGQKKTADGK 229
Cdd:COG4796    76 KLVVDFLNTSLPEELRRRLDVTDFATPVQSIDAFQQGDNVRLVIEPRGDWEYSAYQTDNQFVVEVKPlTEDENKLAQGGK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 230 VKYVGEKLSLNFQNVEVRSVLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKDE 309
Cdd:COG4796   156 KGYTGEKLSLNFQDIPVRSVLQLIADFTGLNLVISDSVTGNITLRLKNVPWDQALDIILKAKGLDKRKNGNVLLVAPAEE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 310 LMAKEKLEYEARSAVADLEPLTTEYIQLNYMRADEAQTMLYGfasgaflasagnnavncsaqaqglgggaaaqasqqgqg 389
Cdd:COG4796   236 LAAREKLELEAKQQIEELEPLRTEYIQLNYAKASDLAKLLKG-------------------------------------- 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 390 eNDQKVLTKRGRATYELKTNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAANSSGSR 469
Cdd:COG4796   278 -QRGSLLSERGSVTVDERTNTLIVRDTPSKLEEIRRLIAKLDIPVRQVLIEARIVEASDSFSRELGVRWGGSGANGTGNN 356

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 470 SISG------GGQALPSVLPNLVMNL-------------LDPANGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVIL 530
Cdd:COG4796   357 RGGIggslngTTAGTPLLPDGLNVNLpaanpagslgltlAKLGGGRLLDLELSALEAEGKGEIISSPRVITADQQEASIE 436

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 531 NGTQIPYITpGTANTPATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAVRFISGISDPAIDTKRIKTQVRVNNGETLV 610
Cdd:COG4796   437 QGTEIPYQE-SSSSGATSVEFKEAVLSLEVTPQITPDGRIILDLDVSKDSPGETVAGGVPAIDTKEIKTQVLVENGETVV 515

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1308963981 611 LGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRILDERLS 665
Cdd:COG4796   516 LGGIYEQTESNSVDKVPFLGDIPLLGWLFKNTTKTDEKRELLIFITPRIVKDALA 570
IV_pilus_PilQ TIGR02515
type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ ...
 234-661 4.00e-156

type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures]


Pssm-ID: 274173 [Multi-domain]  Cd Length: 418  Bit Score: 456.78  E-value: 4.00e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 234 GEKLSLNFQNVEVRSVLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKDELMAK 313
Cdd:TIGR02515   1 GEKISLNFQDIPVRTVLQVIAEFTGLNIVVSDSVQGNITLRLKNVPWDQALDIVLKSKGLDKRRDGNIIYIAPLDELAAQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 314 EKLEYEARSAVADLEPLTTEYIQLNYMRADEAQTMLYGFASGAflasagnnavncsaqaqglgggaaaqasqqgqgendQ 393
Cdd:TIGR02515  81 EKDELEAKKQIENLEPLQTELIQLNYAKASDIAKVLTGVTGGS------------------------------------G 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 394 KVLTKRGRATYELKTNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAA---------- 463
Cdd:TIGR02515 125 GLLSPRGSVTVDPRTNTLIVTDTPENLARIRKLIAELDIPVRQVLIEARIVEATDSFSRELGVRWGITDKngngngtagg 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 464 --NSSGSRSISGGGQALPSVLPNLVMNLLDPA-------------NGSLLNLELRALEADSKGKVISNPRVMTTNQKPAV 528
Cdd:TIGR02515 205 igGNNGTTATGAGGTGNPPFGDNLNVNLATATtaagisfalgkigSGRLLDLELSALESEGKGEIISSPRVLTANNKEAK 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 529 ILNGTQIPYITpGTANTPATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAVRFIS--GISDPAIDTKRIKTQVRVNNG 606
Cdd:TIGR02515 285 IEQGTEIPYQQ-TSSSGATSVEFKEAVLSLEVTPQITPDGRIIMDLLVSKDSPGVVAqaGGGVPAIDKQEINTQVLVKNG 363

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1308963981 607 ETLVLGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRILD 661
Cdd:TIGR02515 364 ETVVIGGIYEQTQTNSEDKVPLLGDIPVLGNLFKKTGKSDEKSELLIFITPRIVN 418
hofQ PRK13568
DNA uptake porin HofQ;
249-660 2.29e-78

DNA uptake porin HofQ;


Pssm-ID: 237430 [Multi-domain]  Cd Length: 381  Bit Score: 254.66  E-value: 2.29e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 249 VLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKDELMAKEKLEYEARSAVADLE 328
Cdd:PRK13568    1 VLQALADYQQLNLVTAPGVGGNLSLRLIEVPWEQALAIILRMGKLSAEREGNVLMVFPEQEIQERQQKTKQQAAPQEQML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 329 PLTTEYIQLNYMRADEAQTMLYgfASGAFLasagnnavncsaqaqglgggaaaqasqqgqgendqkvLTKRGRATYELKT 408
Cdd:PRK13568   81 PLANLTLTLQYADAEEVADSLQ--SQRGGL-------------------------------------LSPRGSVTADKRT 121

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 409 NTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAANSSGsrsisgggQALPSVLPNLVMN 488
Cdd:PRK13568  122 NTLLIRDTPAALAQLKNWLIELDLPLQQVQLAAHIVTISSESLQELGVRWGMGEGKQGN--------TALRINDFNVNLP 193

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 489 LLDPA----------NGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYITPGTANTPATVTFKDAFLCL 558
Cdd:PRK13568  194 LPNPAasagfhlarlGGRLLDLELSALEQENQVDIIASPRLFTSHQQTASIKQGTEIPYTVSSGKSGSTSIEFKEAVLGM 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 559 LVDPQILNNDSVILTVEVQKD----AVRfiSGISDP-AIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGDIP 633
Cdd:PRK13568  274 EVTPKILRNGRITLKLKISQNmpgrTIK--RGEGEMlAIDKQEIQTQVTVKDGETIVLGGIFQQQKRQSVNKVPLLGDIP 351

                         410       420
                  ....*....|....*....|....*..
gi 1308963981 634 GLGHLFKTTIKENSKTELIIFLTPRIL 660
Cdd:PRK13568  352 LLGALFRQDTQQQSRRELVIFITPKLI 378
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 408-663 1.51e-66

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 221.72  E-value: 1.51e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 408 TNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAANSS----GSRSISGGGQALPSVLP 483
Cdd:COG1450    52 TNSLIVRATPEQLREIEELIEQLDVPRRQVLIEAKIVEVSLSDLRELGIDWSALGGNGGgvnfGGTGSLGSLAAAGSLGG 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 484 NLVMNLLDPANgslLNLELRALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYIT-----PGTANTPATVTFKDAFLCL 558
Cdd:COG1450   132 GLNLGLLGGGN---FGALLNALESNGDANVLSSPSILTLNNQEAVIKVGQTVPYVTgstttSSTGNPTTTIEYVDVGITL 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 559 LVDPQILNNDSVILTVEVQKDAV---RFISGISDPAIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGDIPGL 635
Cdd:COG1450   209 KVTPQINEDGTVTLDINPEVSSVtgsTTGGGNGLPTINKREISTTVRVKDGQTVVLGGLIRDEESESESKVPLLGDIPLL 288

                         250       260
                  ....*....|....*....|....*...
gi 1308963981 636 GHLFKTTIKENSKTELIIFLTPRILDER 663
Cdd:COG1450   289 GRLFRSTSKSKEKTELVIFITPTIIRDG 316
hofQ PRK10560
outer membrane porin HofQ; Provisional
 243-661 1.72e-60

outer membrane porin HofQ; Provisional


Pssm-ID: 182549 [Multi-domain]  Cd Length: 386  Bit Score: 207.36  E-value: 1.72e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 243 NVEVRSVLQVIADFTGLNIIASDTVSGNLTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPKD-ELMAKEKLEYEAR 321
Cdd:PRK10560    4 DVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLILRQEGNILSVHSQAwQNENIARQEAEQA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 322 SAVADLePLTTEYIQLNYMRADEaqtmlygfasgafLASAGnnavncsaqaqglgggaaaqasqqgqgendQKVLTKRGR 401
Cdd:PRK10560   84 RAQANL-PLENRSITLQYADAGE-------------LAKAG------------------------------EKLLSAKGS 119

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 402 ATYELKTNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAANSSGSRSISGGGQALPSV 481
Cdd:PRK10560  120 MTVDKRTNRLLLRDNKTALSALEQWVAQMDLPVGQVELAAHIVTINEKSLRELGVKWTLADAQQAGGVGQVTTLGSDLSV 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 482 ---LPNLVMNLlDPANGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYITPGTANTPATVTFKDAFLCL 558
Cdd:PRK10560  200 ataTTRVGFNI-GRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGM 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 559 LVDPQILNNDSVILTVEVQKDAVRFISGISDP---AIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGDIPGL 635
Cdd:PRK10560  279 EVTPTVLQKGRIRLKLHISQNVPGQVLQQADGevlAIDKQEIETQVEVKSGETLALGGIFSRKNKSGQDSVPLLGDIPWL 358

                         410       420
                  ....*....|....*....|....*.
gi 1308963981 636 GHLFKTTIKENSKTELIIFLTPRILD 661
Cdd:PRK10560  359 GQLFRHDGKEDERRELVVFITPRLVS 384
Secretin pfam00263
Bacterial type II and III secretion system protein;
504-660 3.68e-56

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 187.73  E-value: 3.68e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 504 ALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYITPGTANTP--ATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAV 581
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTttTTVEFKDAGLSLKVTPQVTPDGTITLKINPEVSSP 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1308963981 582 RFISGISDPAIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRIL 660
Cdd:pfam00263  81 DGNGGNGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIFITPRIV 159
IV PHA00019
phage assembly protein
 237-660 1.04e-45

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 168.07  E-value: 1.04e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 237 LSLNFQNVEVRSVLQVIADFTGLNIIASDTVSGNLTLR---LKDVPWDQALDLIMQTKGLDKRQNGN--VIWIAPKDELM 311
Cdd:PHA00019   24 LPVELNNSPIREFVSWYSQQTGKSVVLGPDVKGNVTVYsadVNPANLPQFFDSVLRANGFDLVAGGPavVIKQNPNQEDY 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 312 AKE------KLEYEARSAVADLE---PLTTEYIQLNYMRADEAQTMLYGFASGaflasagNNAVNCSAQAQGlgggaaaq 382
Cdd:PHA00019  104 ADDlrdsrdDVFYDNSVPSGAPEvpnDLIVRTFNINNVRASDLLPLVKIFVKS-------NGAPGGSVTDLP-------- 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 383 asqqgqgendqkvltkrgratyelKTNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLgarlSFAA 462
Cdd:PHA00019  169 ------------------------GTNSLVVSGSASQLPALADFISAIDVPRRQVLIEALIFETSLGDGVDL----SFAA 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 463 A-NSSGSRSISGGGQALPSVLPNLVMNLlDPANGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYITPG 541
Cdd:PHA00019  221 GlASGGKVAGGFNTARLTTVLSSAGGSF-GIFNGNVLGLSVKALENSSNSRVLSRPRILTLSGQSGYISVGQNVPFVTGR 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 542 T------ANTPA-TVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAVRFISGISDPAIDTKRIKTQVRVNNGETLVLGGI 614
Cdd:PHA00019  300 VtgeaanVNNPFqTIERKDVGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTIASDIITNQRSLQTTVQVKDGQTLLLGGL 379

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 1308963981 615 FDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRIL 660
Cdd:PHA00019  380 ISSNNTDGDSSVPFLSKIPLIGWLFRSKSDSNEQRTLYVLLTARVI 425
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 408-667 3.76e-45

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 169.87  E-value: 3.76e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 408 TNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGarLSFAAANSSGSRSISGGGQALPSVLPNLV- 486
Cdd:TIGR02517 303 TNSLIITASPQDYKNIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELG--VQWLIAGTGGGVNFSTGSPNSGSLLGASAs 380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 487 -MNLLDPANGSLLNLE------------------LRALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYIT-------- 539
Cdd:TIGR02517 381 aISLGSAGIGLLVTSSsttsgvggtgggpnlgvlLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTgsyntgtg 460

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 540 PGTANTPATVTFKDAFLCLLVDPQILNNDSVILTVEVQKDAVRFI---SGISDPAIDTKRIKTQVRVNNGETLVLGGIFD 616
Cdd:TIGR02517 461 GTNANPFNTYQRKDVGIKLKVTPQINEGGTVRLEIYQEVSSVAPTtvgSAASGPTFNKREIKTVVLVDNGDTVVLGGLIQ 540

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1308963981 617 GDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRILDERLSLR 667
Cdd:TIGR02517 541 DKTSESVTKVPLLGDIPVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDAR 591
pilus_MshL TIGR02519
pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, ...
 408-660 1.21e-36

pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, that is, outer membrane pore proteins associated with delivery of proteins from periplasm to the outside of the cell. Related families include GspD of type II secretion (TIGR02517), the YscC/HrcC family from type III secretion (TIGR02516), and the PilQ secretin of type IV pilus formation (TIGR02515). Members of this family are found in gene clusters associated with MSHA (mannose-sensitive hemagglutinin) and related pili, and appear to be the secretin of this pilus system. [Cell envelope, Surface structures]


Pssm-ID: 274176 [Multi-domain]  Cd Length: 290  Bit Score: 139.05  E-value: 1.21e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 408 TNTLIITDTARKIQEVRELLARL-DVPARQVMIEARV--VVATDG------WS---RDLGARLSFAAAnssgSRSISGGG 475
Cdd:TIGR02519   7 AGLLTVTATPAQIRRVEEYLESLqERIHRQVLIEAKIleVTLSDNhqqgidWSnfnGSGLARYKALGA----ANSNDSSG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 476 QALPSVLPNL-VMNLLDPAN-GSLLNLELRALEADSKGKVISNPRVMTTNQKPAVILNGTQIPYITP---------GTAN 544
Cdd:TIGR02519  83 NQFSSGLGFLdNIGLPTGVNsGFGFDSIINFLATFGDTKVLSNPKVMALNNQPAVISVGDNIRYVTEesstgttggTTST 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 545 TPATVTFKDAFLCLLVD--PQILNNDSVILTV-----EVQKDAVRFISGISD-----PAIDTKRIKTQVRVNNGETLVLG 612
Cdd:TIGR02519 163 ASSDTRVDSVFSGIVLGvtPQISDDGKVILNVhpsisEVKPQSIDLNPVGNGaevalPEISVKEMSSVLRVKDGDTVVLG 242

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1308963981 613 GIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRIL 660
Cdd:TIGR02519 243 GLIDKKKSNTKTGLPFLGDIPGLGYLFGYKSKSKKKTELVIIIRPSVV 290
CpaC COG4964
Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular ...
 435-659 2.21e-32

Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443990 [Multi-domain]  Cd Length: 456  Bit Score: 130.76  E-value: 2.21e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 435 RQVMIEARVV-VATDGwSRDLGARLSfAAANSSGSRSISGGGQALPSVLPNLVMNLLDP--ANGSLLNLELRALEADSKG 511
Cdd:COG4964   175 QQVMLKVRVAeVSRSV-LKQLGINWS-GLGSSGGFSFGLLTGGLLSGLLGGATAGAFSGfgFGNASISATLDALEQNGLA 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 512 KVISNPRVMTTNQKPAVILNGTQIPYITPGTANTPaTVTFKD-----AFLcllvdPQILNNDSVILTVEVQ------KDA 580
Cdd:COG4964   253 RVLAEPNLTALSGETASFLAGGEFPIPVAQGDGTI-TVEYKEfgvslNFT-----PTVLSNGRISLKVAPEvseldpSNA 326

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1308963981 581 VRfISGISDPAIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGDIPGLGHLFKTTIKENSKTELIIFLTPRI 659
Cdd:COG4964   327 VT-LNGITIPGLTTRRAETTVELRSGQSFAIAGLLSSNTRQNVSKVPGLGDIPILGALFRSRSFQRNETELVIIVTPYL 404
type_III_yscC TIGR02516
type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to ...
 408-662 3.72e-28

type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to the type IV pilus secretin PilQ (TIGR02515) are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). The clade described by this model contains the outer membrane pore proteins of bacterial type III secretion systems, typified by YscC for animal pathogens and HrcC for plant pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274174 [Multi-domain]  Cd Length: 462  Bit Score: 118.25  E-value: 3.72e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 408 TNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSfAAANSSGSRSISGGGQALPSvlpNLVM 487
Cdd:TIGR02516 207 TNAVLIRDRPERMAIYEQLIQQLDVPPRLIEISAWIIDIDASDLSQLGVDWQ-ATLGAGDRQTGFNVSAGAGL---GATG 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 488 NLLDPANGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVI---------LNGTQIPYITPGTANTPATVTfkdaflcl 558
Cdd:TIGR02516 283 SSIVTSDGDYFMARVNALEQTGKAKIVSRPSVLTLENVQAVLdnnrtfyvkVSGERVADLESVTAGTSLRVT-------- 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 559 lvdPQILNNDS----VILTVEVQKDAVRFISGISD---PAIDTKRIKTQVRVNNGETLVLGGIFDGDENSSVNKVPLLGD 631
Cdd:TIGR02516 355 ---PRVIGDEGaqrqIKLNVDIEDGQQKTDGTSTVdalPEIKRTEINTQARVGHGQSLLIGGYYRDESADSVDGIPLLGD 431

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1308963981 632 IPGLGHLFKTTIKENSKTELIIFLTPRILDE 662
Cdd:TIGR02516 432 IPLLGNLFRSTSKEKSRVVRLFLITPKIVRD 462
PRK15346 PRK15346
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
405-645 7.30e-17

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237950 [Multi-domain]  Cd Length: 499  Bit Score: 83.97  E-value: 7.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 405 ELKTNTLIITDTARKIQEVRELLARLDVpaRQVMIEARV----VVATD------GWSRDL---GARLSFAAAnssgsrSI 471
Cdd:PRK15346  241 DPRQNAVIVRDRAANMAIYRSLITQLDQ--RPQMIEISVsiidVDAGDinqlgiDWSASAslgGGKISFNSG------FA 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 472 SGGGQALPSVLpnlvmnlldpANGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVI---------LNGTQIP---YIT 539
Cdd:PRK15346  313 DGNASGFSTVI----------SNTGNFMVRLNALEKNSKAKILSQPSVVTLNNIQAVLdknvtfytkLQGEKVAkleSIT 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 540 PGTantpatvtfkdaflCLLVDPQILN---NDSVILTVEVQKDAVRFISGISD--PAIDTKRIKTQVRVNNGETLVLGGI 614
Cdd:PRK15346  383 TGS--------------LLRVTPRLIDdngTQKVMLNLNIQDGQQSATQSETDplPEVQNSEIATQATLKAGQSLLLGGF 448

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1308963981 615 FDGDENSSVNKVPLLGDIPGLGHLFKTTIKE 645
Cdd:PRK15346  449 IQDKQIESQNKIPLLGDIPLIGGLFRSTDKQ 479
AMIN pfam11741
AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the ...
 4-87 2.75e-10

AMIN domain; This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localizes to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localization of periplasmic protein complexes.


Pssm-ID: 463338  Cd Length: 96  Bit Score: 57.31  E-value: 2.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981   4 VRVTLKNALTATPAGFTVGNPPRIALDLPDTGNAMGRNTVEANLGPLSSVNVVQ-AGTRTRLVLNLNKSVEYEAQI--DG 80
Cdd:pfam11741  10 TELELETSGGEKYQVFTLSNPNRLVIDIPGAQLGLPLKRIENPSPGIKSVRVGQfDPNTVRVVVDLDGSVLPQVPVfkSG 89


                  ....*..
gi 1308963981  81 KTLLVAL 87
Cdd:pfam11741  90 EGLVVDL 96
PRK15339 PRK15339
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
408-664 4.14e-08

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237948 [Multi-domain]  Cd Length: 559  Bit Score: 56.32  E-value: 4.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 408 TNTLIITDTARKIQEVRELLARLDVPARQVMIEARVVVATDGWSRDLGARLSFAAanssgsrsisGGGQALPSVLPNLVM 487
Cdd:PRK15339  274 TNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIIDLDKSDLEQLGVNWSGSI----------TIGDKLGVSLNQSSI 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 488 NLLDpanGSLLNLELRALEADSKGKVISNPRVMTTNQKPAVILNG------------TQIPYITPGTAntpatvtfkdaf 555
Cdd:PRK15339  344 STLD---GSRFIAAVMALEQKKKANVVSRPVVLTQENIPAIFDNNrtfytklvgernVALEHVTYGTM------------ 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308963981 556 lcLLVDPQILNNDSV--ILTVEVQKDAVRFIS---GISD-PAIDTKRIKTQVRVNNGETLVLGGiFDGDENSS-VNKVPL 628
Cdd:PRK15339  409 --ISVLPRFSADGQIemSLDIEDGNEKTPQSDtttSVDAlPEVGRTLISTIARVPQGKSLLIGG-YTRDANTDeVQSIPF 485

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1308963981 629 LGDIPGLGHLFKTTIKENSKTELIIFLTPRILDERL 664
Cdd:PRK15339  486 LGSLPLIGSLFRYSSKNKSNIVRVFLIEPREIVEPL 521
STN smart00965
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 259-307 1.09e-05

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 198033 [Multi-domain]  Cd Length: 52  Bit Score: 42.88  E-value: 1.09e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1308963981  259 LNIIASD--TVSGNLTLRLKDVPWDQALDLIMQTKGLD-KRQNGNVIWIAPK 307
Cdd:smart00965   1 LNFVYDPalVAGRRVSLLLGNVTVEQALDRLLAGTGLTyRRIGGNTIVLSPA 52
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 396-436 7.13e-05

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 41.05  E-value: 7.13e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1308963981 396 LTKRGRATYELKTNTLIITDTARKIQEVRELLARLDVPARQ 436
Cdd:pfam03958  28 LSKRGSVVADPRTNSLIVSGPPEYVELVRQLIKQLDVPRAQ 68
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 261-307 3.29e-04

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 38.65  E-value: 3.29e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1308963981 261 IIASDTVSGN--LTLRLKDVPWDQALDLIMQTKGLDKRQNGNVIWIAPK 307
Cdd:pfam07660   3 LYDSDLVDGKqsVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRPK 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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