|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02102 |
PRK02102 |
ornithine carbamoyltransferase; Validated |
1-310 |
0e+00 |
|
ornithine carbamoyltransferase; Validated
Pssm-ID: 179366 [Multi-domain] Cd Length: 331 Bit Score: 587.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MNLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKND 80
Cdd:PRK02102 3 FNLKGRSFLKLLDFTPEEIEYLIDLSIELKAAKKAGIEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPND 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 81 IQLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAG 160
Cdd:PRK02102 83 SQLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFGPLKGLKLAYVG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DGRNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLA-CVKGADIIYSDVWCSMGEEDKA 239
Cdd:PRK02102 163 DGRNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKETGAKITITEDPEeAVKGADVIYTDVWVSMGEEDEW 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 240 AERVKLLKPYQVNATLMAKTEKDNTIFLHCLPA-----------------VKGNEVTEEVFEKHARIIFDQAENRMHTIK 302
Cdd:PRK02102 243 EERIKLLKPYQVNMDLMKATGNPDVIFMHCLPAfhdtetkvgkeiaekygLKGLEVTDEVFESKYSIVFDEAENRMHTIK 322
|
....*...
gi 1308681316 303 AVMVATAG 310
Cdd:PRK02102 323 AVMVATLG 330
|
|
| ArgF |
COG0078 |
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ... |
1-311 |
0e+00 |
|
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis
Pssm-ID: 439848 [Multi-domain] Cd Length: 310 Bit Score: 534.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MNLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKND 80
Cdd:COG0078 1 TNLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 81 IQLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAG 160
Cdd:COG0078 81 SQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DGrNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLA-CVKGADIIYSDVWCSMGEEDKA 239
Cdd:COG0078 161 DG-NNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAeAVKGADVVYTDVWVSMGQEEEA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1308681316 240 AERVKLLKPYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVATAGK 311
Cdd:COG0078 240 EERIKAFKPYQVNEELMALA-KPDAIFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLLGG 310
|
|
| orni_carb_tr |
TIGR00658 |
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ... |
6-310 |
1.06e-162 |
|
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]
Pssm-ID: 129743 [Multi-domain] Cd Length: 304 Bit Score: 454.89 E-value: 1.06e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 6 RSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDIQLGH 85
Cdd:TIGR00658 1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 86 KESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAGDGrNN 165
Cdd:TIGR00658 81 GESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDG-NN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 166 MANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSED-LACVKGADIIYSDVWCSMGEEDKAAERVK 244
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDpVEAVKGADVIYTDVWVSMGEEDKKEERLK 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1308681316 245 LLKPYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVATAG 310
Cdd:TIGR00658 240 LFRPYQVNEELMELA-KPEVIFMHCLPAHRGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMVALLG 304
|
|
| OTCace_N |
pfam02729 |
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; |
7-146 |
6.99e-74 |
|
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
Pssm-ID: 460665 [Multi-domain] Cd Length: 140 Bit Score: 223.46 E-value: 6.99e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 7 SLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDIQLGHK 86
Cdd:pfam02729 1 HFLSLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 87 ESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKE 146
Cdd:pfam02729 81 ESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02102 |
PRK02102 |
ornithine carbamoyltransferase; Validated |
1-310 |
0e+00 |
|
ornithine carbamoyltransferase; Validated
Pssm-ID: 179366 [Multi-domain] Cd Length: 331 Bit Score: 587.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MNLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKND 80
Cdd:PRK02102 3 FNLKGRSFLKLLDFTPEEIEYLIDLSIELKAAKKAGIEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPND 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 81 IQLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAG 160
Cdd:PRK02102 83 SQLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFGPLKGLKLAYVG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DGRNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLA-CVKGADIIYSDVWCSMGEEDKA 239
Cdd:PRK02102 163 DGRNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKETGAKITITEDPEeAVKGADVIYTDVWVSMGEEDEW 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 240 AERVKLLKPYQVNATLMAKTEKDNTIFLHCLPA-----------------VKGNEVTEEVFEKHARIIFDQAENRMHTIK 302
Cdd:PRK02102 243 EERIKLLKPYQVNMDLMKATGNPDVIFMHCLPAfhdtetkvgkeiaekygLKGLEVTDEVFESKYSIVFDEAENRMHTIK 322
|
....*...
gi 1308681316 303 AVMVATAG 310
Cdd:PRK02102 323 AVMVATLG 330
|
|
| ArgF |
COG0078 |
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ... |
1-311 |
0e+00 |
|
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis
Pssm-ID: 439848 [Multi-domain] Cd Length: 310 Bit Score: 534.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MNLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKND 80
Cdd:COG0078 1 TNLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 81 IQLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAG 160
Cdd:COG0078 81 SQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DGrNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLA-CVKGADIIYSDVWCSMGEEDKA 239
Cdd:COG0078 161 DG-NNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAeAVKGADVVYTDVWVSMGQEEEA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1308681316 240 AERVKLLKPYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVATAGK 311
Cdd:COG0078 240 EERIKAFKPYQVNEELMALA-KPDAIFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLLGG 310
|
|
| PRK04284 |
PRK04284 |
ornithine carbamoyltransferase; Provisional |
2-310 |
1.46e-166 |
|
ornithine carbamoyltransferase; Provisional
Pssm-ID: 235269 [Multi-domain] Cd Length: 332 Bit Score: 465.76 E-value: 1.46e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 2 NLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDI 81
Cdd:PRK04284 3 NLRNRSFLTLLDFTPKEIEYLLDLSEDLKRAKYAGIEVQKLKGKNIALIFEKDSTRTRCAFEVAAYDQGAHVTYLGPTGS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 82 QLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQF-GTLKGLTFVYAG 160
Cdd:PRK04284 83 QMGKKESTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEHLkKPYKDIKFTYVG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DGRNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDL-ACVKGADIIYSDVWCSMGEEDKA 239
Cdd:PRK04284 163 DGRNNVANALMQGAAIMGMDFHLVCPKELNPDDELLNKCKEIAAETGGKITITDDIdEGVKGSDVIYTDVWVSMGEPDEV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 240 -AERVKLLKPYQVNATLMAKTEKDNTIFLHCLPA-----------------VKGNEVTEEVFEKHARIIFDQAENRMHTI 301
Cdd:PRK04284 243 wEERIKLLKPYQVNKEMMKKTGNPNAIFEHCLPSfhdldtkvgkeifekygLKEMEVTDEVFESKASVVFDEAENRMHTI 322
|
....*....
gi 1308681316 302 KAVMVATAG 310
Cdd:PRK04284 323 KAVMVATLG 331
|
|
| orni_carb_tr |
TIGR00658 |
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ... |
6-310 |
1.06e-162 |
|
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]
Pssm-ID: 129743 [Multi-domain] Cd Length: 304 Bit Score: 454.89 E-value: 1.06e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 6 RSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDIQLGH 85
Cdd:TIGR00658 1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 86 KESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAGDGrNN 165
Cdd:TIGR00658 81 GESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDG-NN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 166 MANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSED-LACVKGADIIYSDVWCSMGEEDKAAERVK 244
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDpVEAVKGADVIYTDVWVSMGEEDKKEERLK 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1308681316 245 LLKPYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVATAG 310
Cdd:TIGR00658 240 LFRPYQVNEELMELA-KPEVIFMHCLPAHRGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMVALLG 304
|
|
| PRK00779 |
PRK00779 |
ornithine carbamoyltransferase; Provisional |
2-306 |
5.87e-155 |
|
ornithine carbamoyltransferase; Provisional
Pssm-ID: 234835 [Multi-domain] Cd Length: 304 Bit Score: 435.29 E-value: 5.87e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 2 NLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDI 81
Cdd:PRK00779 1 MLMGRHFLSLDDLSPEELEELLDLAAELKKKRKAGEPHPPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIFLSPRDT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 82 QLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAGD 161
Cdd:PRK00779 81 QLGRGEPIEDTARVLSRYVDAIMIRTFEHETLEELAEYSTVPVINGLTDLSHPCQILADLLTIYEHRGSLKGLKVAWVGD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 162 GrNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMkscKEYAELSGSTITLSED-LACVKGADIIYSDVWCSMGEEDKAA 240
Cdd:PRK00779 161 G-NNVANSLLLAAALLGFDLRVATPKGYEPDPEIV---EKIAKETGASIEVTHDpKEAVKGADVVYTDVWVSMGQEAEAE 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1308681316 241 ERVKLLKPYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMV 306
Cdd:PRK00779 237 ERLKAFAPYQVNEELMALA-KPDAIFMHCLPAHRGEEVTDEVIDGPQSVVWDEAENRLHAQKALLA 301
|
|
| PRK03515 |
PRK03515 |
ornithine carbamoyltransferase subunit I; Provisional |
1-311 |
2.37e-153 |
|
ornithine carbamoyltransferase subunit I; Provisional
Pssm-ID: 179587 [Multi-domain] Cd Length: 336 Bit Score: 432.60 E-value: 2.37e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MN-LKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKN 79
Cdd:PRK03515 1 MNqFYQRHFLRLLDFTPAELNSLLQLAAKLKADKKNGKEEQKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 80 DIQLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQF--GTLKGLTFV 157
Cdd:PRK03515 81 GSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpgKAFNEMTLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 158 YAGDGRNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLAC-VKGADIIYSDVWCSMGE- 235
Cdd:PRK03515 161 YAGDARNNMGNSLLEAAALTGLDLRLVAPKACWPEAALVTECRALAQKNGGNITLTEDIAEgVKGADFIYTDVWVSMGEp 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 236 EDKAAERVKLLKPYQVNATLMAKTEKDNTIFLHCLPAVK------------------GNEVTEEVFEKHARIIFDQAENR 297
Cdd:PRK03515 241 KEVWAERIALLRPYQVNSKMMQLTGNPQVKFLHCLPAFHddqttlgkkmaeeyglhgGMEVTDEVFESAHSIVFDQAENR 320
|
330
....*....|....
gi 1308681316 298 MHTIKAVMVATAGK 311
Cdd:PRK03515 321 LHTIKAVMVATLSK 334
|
|
| PRK12562 |
PRK12562 |
ornithine carbamoyltransferase subunit F; Provisional |
6-311 |
1.43e-132 |
|
ornithine carbamoyltransferase subunit F; Provisional
Pssm-ID: 105755 Cd Length: 334 Bit Score: 379.79 E-value: 1.43e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 6 RSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDIQLGH 85
Cdd:PRK12562 7 KHFLKLLDFTPAELNSLLQLAAKLKADKKNGKEVARLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 86 KESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQF--GTLKGLTFVYAGDGR 163
Cdd:PRK12562 87 KESIKDTARVLGRMYDGIQYRGHGQEVVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpgKAFNEMTLVYAGDAR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 164 NNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLAC-VKGADIIYSDVWCSMGE-EDKAAE 241
Cdd:PRK12562 167 NNMGNSMLEAAALTGLDLRLVAPQACWPEASLVAECSALAQKHGGKITLTEDIAAgVKGADFIYTDVWVSMGEpKEKWAE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 242 RVKLLKPYQVNATLMAKTEKDNTIFLHCLPAVK------------------GNEVTEEVFEKHARIIFDQAENRMHTIKA 303
Cdd:PRK12562 247 RIALLRGYQVNSKMMALTGNPQVKFLHCLPAFHddqttlgkkmakefglhgGMEVTDEVFESPASIVFDQAENRMHTIKA 326
|
....*...
gi 1308681316 304 VMVATAGK 311
Cdd:PRK12562 327 VMVATLAK 334
|
|
| PRK01713 |
PRK01713 |
ornithine carbamoyltransferase; Provisional |
2-308 |
6.54e-130 |
|
ornithine carbamoyltransferase; Provisional
Pssm-ID: 167263 [Multi-domain] Cd Length: 334 Bit Score: 373.17 E-value: 6.54e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 2 NLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDI 81
Cdd:PRK01713 4 NLKNRHLLSLVNHTEREIKYLLDLSRDLKRAKYAGTEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPNSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 82 QLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGT-LKGLTFVYAG 160
Cdd:PRK01713 84 QIGHKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFNGLTDEFHPTQMLADVLTMIENCDKpLSEISYVYIG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DGRNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDL-ACVKGADIIYSDVWCSMGEEDKA 239
Cdd:PRK01713 164 DARNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKESGARITVTDDIdKAVKGVDFVHTDVWVSMGEPLET 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 240 -AERVKLLKPYQVNATLMAKTEKDNTIFLHCLPA-------------------VKGNEVTEEVFEKHARIIFDQAENRMH 299
Cdd:PRK01713 244 wGERIKLLMPYQVTPELMKRTGNPKVKFMHCLPAfhnsetkvgrqiaekypelANGIEVTEDVFESPMNIAFEQAENRMH 323
|
....*....
gi 1308681316 300 TIKAVMVAT 308
Cdd:PRK01713 324 TIKAVMVAS 332
|
|
| PLN02342 |
PLN02342 |
ornithine carbamoyltransferase |
2-311 |
5.50e-106 |
|
ornithine carbamoyltransferase
Pssm-ID: 177976 [Multi-domain] Cd Length: 348 Bit Score: 312.88 E-value: 5.50e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 2 NLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDL-LCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKND 80
Cdd:PLN02342 42 KSKPKHFLHIDDFDKEEILGLLDRAKEVKALLKSGDRSFQpFKGKSMAMIFTKPSMRTRVSFETGFFLLGGHALYLGPDD 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 81 IQLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAG 160
Cdd:PLN02342 122 IQLGKREETRDIARVLSRYNDIIMARVFAHQDVLDLAEYSSVPVINGLTDYNHPCQIMADALTIIEHIGRLEGTKVVYVG 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DGrNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMksckEYAELSG-STITLSEDLA-CVKGADIIYSDVWCSMGEEDK 238
Cdd:PLN02342 202 DG-NNIVHSWLLLAAVLPFHFVCACPKGYEPDAKTV----EKARAAGiSKIEITNDPAeAVKGADVVYTDVWASMGQKEE 276
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1308681316 239 AAERVKLLKPYQVNATLMAKTEKDnTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVATAGK 311
Cdd:PLN02342 277 AEKRKKAFQGFQVNEALMKLAGPQ-AYFMHCLPAERGVEVTDGVMEAPNSIVFPQAENRMHAQNAIMLHQLGK 348
|
|
| PRK14805 |
PRK14805 |
ornithine carbamoyltransferase; Provisional |
8-307 |
4.93e-97 |
|
ornithine carbamoyltransferase; Provisional
Pssm-ID: 237819 [Multi-domain] Cd Length: 302 Bit Score: 288.51 E-value: 4.93e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 8 LLTLKDFSPQEIDYLLELAMDLK---AKKRMGirgdlLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDIQLG 84
Cdd:PRK14805 4 LLSIKELTQQQLLDLLALAKTIKanpAEYRQA-----LAGKSVVMLFEKPSLRTRVSFDIGINKLGGHCLYLDQQNGALG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 85 HKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAGDGrN 164
Cdd:PRK14805 79 KRESVADFAANLSCWADAIVARVFSHSTIEQLAEHGSVPVINALCDLYHPCQALADFLTLAEQFGDVSKVKLAYVGDG-N 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 165 NMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLACVKGADIIYSDVWCSMGEEDKAAERVK 244
Cdd:PRK14805 158 NVTHSLMYGAAILGATMTVICPPGHFPDGQIVAEAQELAAKSGGKLVLTSDIEAIEGHDAIYTDTWISMGDDTPLAEIKA 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1308681316 245 LLKPYQVNATLMAKTEKdnTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVA 307
Cdd:PRK14805 238 KFAPYQVNKALMEKAGA--TFVMHCQPAHRGVEITSEVMDGEGSLILQQAENRMHAQNAVLVT 298
|
|
| OTCace_N |
pfam02729 |
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; |
7-146 |
6.99e-74 |
|
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
Pssm-ID: 460665 [Multi-domain] Cd Length: 140 Bit Score: 223.46 E-value: 6.99e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 7 SLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDIQLGHK 86
Cdd:pfam02729 1 HFLSLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 87 ESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTIKE 146
Cdd:pfam02729 81 ESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
|
|
| OTCace |
pfam00185 |
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; |
155-308 |
1.70e-66 |
|
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
Pssm-ID: 425511 [Multi-domain] Cd Length: 154 Bit Score: 205.15 E-value: 1.70e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 155 TFVYAGDGRNNMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLA-CVKGADIIYSDVWCSM 233
Cdd:pfam00185 1 KIAYVGDGHNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAeAVKGADVVYTDVWQSM 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1308681316 234 GEEDKAAERVKLLKPYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVAT 308
Cdd:pfam00185 81 GQEKEREERLKAFKPYQVNEELMKLA-KKDAIFMHCLPAHRGEEVTDDVFDGPRSVVFDQAENRLHAQKALLALL 154
|
|
| PRK04523 |
PRK04523 |
N-acetylornithine carbamoyltransferase; Reviewed |
6-310 |
1.66e-50 |
|
N-acetylornithine carbamoyltransferase; Reviewed
Pssm-ID: 235304 [Multi-domain] Cd Length: 335 Bit Score: 170.31 E-value: 1.66e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 6 RSLLTLKDFSPQEIDYLLELAMDLKAKKRmgirGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYL--GKNDIQL 83
Cdd:PRK04523 4 KHFLNTQDWSRAELDALLTQAAAFKRNKL----GSALKGKSIALVFFNPSLRTRTSFELGAFQLGGHAVVLqpGKDAWPI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 84 GHKE-SVMD---------TARVLGRLFDGIQFRGFS---------QDTV-EKLAQYSGVPVWNgLTDDYHPTQILADLMT 143
Cdd:PRK04523 80 EFELgAVMDgeteehireVARVLSRYVDLIGVRAFPkfvdwskdrQDQVlNSFAKYSTVPVIN-METITHPCQELAHALA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 144 IKEQFG-TLKGLTFV--YAGDGRN-NMA--NSLMIGCSKMGIHYTLFAPKELWP-KENLMKSCKEYAELSGSTITLSEDL 216
Cdd:PRK04523 159 LQEHFGtTLRGKKYVltWTYHPKPlNTAvaNSALLIATRLGMDVTLLCPTPDYIlDERYMDWAEQNAAESGGSLTVSHDI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 217 -ACVKGADIIYSDVWCSM----GEEDKAAERVKLlKPYQVNATLMAKTekDNTIFLHCLPAVKGNEVTEEVFEKHARIIF 291
Cdd:PRK04523 239 dSAYAGADVVYAKSWGALpffgNWEPEKPIRDQY-QHFIVDERKMALT--NNGVFSHCLPLRRNVKVTDAVMDSPNCIAI 315
|
330
....*....|....*....
gi 1308681316 292 DQAENRMHTIKAVMVATAG 310
Cdd:PRK04523 316 DEAENRLHVQKAIMAALAS 334
|
|
| PRK14804 |
PRK14804 |
ornithine carbamoyltransferase; Provisional |
6-306 |
7.34e-50 |
|
ornithine carbamoyltransferase; Provisional
Pssm-ID: 173265 [Multi-domain] Cd Length: 311 Bit Score: 167.90 E-value: 7.34e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 6 RSLLTLKDFSPQEIDYLLELAMDLKaKKRMGIRGDLlCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLG--KNDIQL 83
Cdd:PRK14804 7 KHLISWEDWSDSEILDLLDFAVHVK-KNRVNYAGHM-SGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLDwmASNFQL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 84 ghkeSVMD-TARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGLTDDYHPTQILADLMTI--KEQFGTLKGLTFVYAG 160
Cdd:PRK14804 85 ----SDIDlEARYLSRNVSVIMARLKKHEDLLVMKNGSQVPVINGCDNMFHPCQSLADIMTIalDSPEIPLNQKQLTYIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 161 DgRNNMANSLMIGCSKMGIHYTLFAPkeLWPKENLMKSCKEYAELSGsTITLSEDL-ACVKGADIIYSDVWCSM------ 233
Cdd:PRK14804 161 V-HNNVVNSLIGITAALGIHLTLVTP--IAAKENIHAQTVERAKKKG-TLSWEMNLhKAVSHADYVYTDTWLDMeffndp 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1308681316 234 GEEDKAAERVKLLKPYQVNATLMaktEKDNTIFLHCLPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMV 306
Cdd:PRK14804 237 SYADKKKQRMELMMPYQINSSLM---EKTNAKVMHDMPIHAGYEITREVVLSDRSIIFQQAENRLDAQKAVIL 306
|
|
| PyrB |
COG0540 |
Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; ... |
1-311 |
1.62e-49 |
|
Aspartate carbamoyltransferase, catalytic subunit [Nucleotide transport and metabolism]; Aspartate carbamoyltransferase, catalytic subunit is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440306 [Multi-domain] Cd Length: 306 Bit Score: 166.77 E-value: 1.62e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MNLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFtvgcvdegghpE----YL 76
Cdd:COG0540 1 MSFKMRHLLSIEDLSREEIEELLDTAEEFKEVLRPIKKVPLLRGKTVANLFFEPSTRTRLSF-----------ElaakRL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 77 GKNDIQLGHK-------ESVMDTARVLGRL-FDGIQFRGFSQDTVEKLAQYSGVPVWNGlTD--DYHPTQILADLMTIKE 146
Cdd:COG0540 70 GADVINFSAStssvskgESLADTIRTLEAYgADAIVIRHPQEGAARLLAEHVDVPVINA-GDgaHEHPTQALLDLYTIRE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 147 QFGTLKGLTFVYAGD---GRnnMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELsgstitlsEDLacVKGAD 223
Cdd:COG0540 149 EFGRLDGLKVAIVGDlkhSR--VARSNIKALSKLGAEVTLVAPPTLLPEEIEELGVEVTTDL--------DEA--LPDAD 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 224 IIYsdvwcsM---------GEEDKAAERVKllKPYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFE-KHARiIFDQ 293
Cdd:COG0540 217 VVY------MlriqkerftDGLFPSYREYK--RSYGLTAERLALA-KPDAIVMHPGPRNRGVEIDSDVDDtPRSV-IFEQ 286
|
330 340
....*....|....*....|..
gi 1308681316 294 AEN----RMhtikAVMVATAGK 311
Cdd:COG0540 287 VTNgvavRM----ALLYLLLGG 304
|
|
| pyrB |
PRK00856 |
aspartate carbamoyltransferase catalytic subunit; |
1-305 |
2.43e-42 |
|
aspartate carbamoyltransferase catalytic subunit;
Pssm-ID: 234849 [Multi-domain] Cd Length: 305 Bit Score: 147.91 E-value: 2.43e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MNLKGRSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRG-DLLCGKNVALIFEKPSTRTRCAFtvgcvdegghpE----Y 75
Cdd:PRK00856 1 NPLKMKHLLSIEDLSREEIELLLDTAEEFKEVLRREVKKvPLLRGKTVANLFFEPSTRTRLSF-----------ElaakR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 76 LGKNDIQLGHK-------ESVMDTARVLGRLF-DGIQFRGFSQDTVEKLAQYSGVPVWNGltDD---YHPTQILADLMTI 144
Cdd:PRK00856 70 LGADVINFSAStssvskgETLADTIRTLSAMGaDAIVIRHPQSGAARLLAESSDVPVINA--GDgshQHPTQALLDLLTI 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 145 KEQFGTLKGLTFVYAGD---GRnnMANSLMIGCSKMGIHYTLFAPKELWPKEnlMKSCKEYAELsgstitlsEDLacVKG 221
Cdd:PRK00856 148 REEFGRLEGLKVAIVGDikhSR--VARSNIQALTRLGAEVRLIAPPTLLPEG--MPEYGVHTDL--------DEV--IED 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 222 ADIIYsdvwcsM---------GEEDKAAERVKLLkpYQVNATLMAKTeKDNTIFLHCLPAVKGNEVTEEVFE-KHARiIF 291
Cdd:PRK00856 214 ADVVM------MlrvqkermdGGLLPSYEEYKRS--YGLTAERLALA-KPDAIVMHPGPVNRGVEIASDVADgPQSV-IF 283
|
330
....*....|....*...
gi 1308681316 292 DQAEN----RMhtikAVM 305
Cdd:PRK00856 284 EQVTNgvavRM----AVL 297
|
|
| asp_carb_tr |
TIGR00670 |
aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB ... |
6-305 |
1.40e-37 |
|
aspartate carbamoyltransferase; Aspartate transcarbamylase (ATCase) is an alternate name.PyrB encodes the catalytic chain of aspartate carbamoyltransferase, an enzyme of pyrimidine biosynthesis, which organizes into trimers. In some species, including E. coli and the Archaea but excluding Bacillus subtilis, a regulatory subunit PyrI is also present in an allosterically regulated hexameric holoenzyme. Several molecular weight classes of ATCase are described in MEDLINE:96303527 and often vary within taxa. PyrB and PyrI are fused in Thermotoga maritima.Ornithine carbamoyltransferases are in the same superfamily and form an outgroup. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis]
Pssm-ID: 273209 [Multi-domain] Cd Length: 301 Bit Score: 135.56 E-value: 1.40e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 6 RSLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGhpEYLGKNDIQ--- 82
Cdd:TIGR00670 1 RHLISISDLSREEIELLLETARELEQVLNGKEPLKLLKGKILANLFFEPSTRTRLSFETAMKRLGG--SVVNFSDSEtss 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 83 LGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWN-GLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAGD 161
Cdd:TIGR00670 79 VAKGETLADTIKTLSGYVDAIVIRHPLEGAARLAAEVSEVPVINaGDGSNQHPTQTLLDLYTIYEEFGRLDGLKIALVGD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 162 ---GRnnMANSLMIGCSKMGIHYTLFAPKELWPKENLMKSCKEYAELSGSTITLSEDLAcvkGADIIYSdvwCSMGEE-- 236
Cdd:TIGR00670 159 lkyGR--TVHSLAEALTRFGVEVYLISPEELRMPKEILEELKAKGIKVRETESLEEVID---EADVLYV---TRIQKErf 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1308681316 237 DKAAERVKLLKPYQVNATLmAKTEKDNTIFLHCLPavKGNEVTEEVFE-KHARiIFDQAEN----RMHTIKAVM 305
Cdd:TIGR00670 231 PDPEEYEKVKGSYGITLER-LEAAKKGVIIMHPLP--RVDEIDPSVDDtPHAK-YFKQAFNgvpvRMALLALLL 300
|
|
| PRK08192 |
PRK08192 |
aspartate carbamoyltransferase; Provisional |
1-298 |
5.06e-24 |
|
aspartate carbamoyltransferase; Provisional
Pssm-ID: 169269 [Multi-domain] Cd Length: 338 Bit Score: 99.80 E-value: 5.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 1 MNLKGRSLLTLKDFSPQEIDYLLELA--MDLKAKKRMgiRGDLLCGKNVALIFEKPSTRTRCAFtvGCVDE--GGH-PEY 75
Cdd:PRK08192 1 MQFQGSHILSVNQLDRDAIQRIFNVAdrMEPYALREK--RTRVLEGAILGNLFFEPSTRTRVSF--GCAFNllGGHvRET 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 76 LGKNDIQLGHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWNGlTD--DYHPTQILADLMTIKEQF----G 149
Cdd:PRK08192 77 TGMASSSLSKGESLYDTARVLSTYSDVIAMRHPDAGSVKEFAEGSRVPVING-GDgsNEHPTQALLDLFTIQKELahagR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 150 TLKGLTFVYAGD---GRNnmANSLM-IGCSKMGIHYTLFAPKELWPKENLMKSCKEYaelsGSTITLSEDLA-CVKGADI 224
Cdd:PRK08192 156 GIDGMHIAMVGDlkfGRT--VHSLSrLLCMYKNVSFTLVSPKELAMPDYVISDIENA----GHKITITDQLEgNLDKADI 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 225 IYS-----DVWCSMGEEDKAAERVKLlkpyqvNATLMAKTEKDNTIFLHCLP---AVKGNEVTEEVFEKHARIIFDQAEN 296
Cdd:PRK08192 230 LYLtriqeERFPSQEEANKYRGKFRL------NQSIYTQHCKSNTVIMHPLPrdsRAQANELDNDLNSHPNLAIFRQADN 303
|
....*.
gi 1308681316 297 ----RM 298
Cdd:PRK08192 304 glliRM 309
|
|
| PRK07200 |
PRK07200 |
aspartate/ornithine carbamoyltransferase family protein; Validated |
6-307 |
5.35e-19 |
|
aspartate/ornithine carbamoyltransferase family protein; Validated
Pssm-ID: 235961 [Multi-domain] Cd Length: 395 Bit Score: 86.33 E-value: 5.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 6 RSLLTLKDF------SPQEIDYLLELAMDLKAKKRMGIRGDLL-CGKNVALiFEKPSTRTRCAFTVGCVDEGGHPEYLGK 78
Cdd:PRK07200 15 TSHMHEKDFlltwekTPDELKAVLDVADALRALREENISTKVFnSGLGISV-FRDNSTRTRFSYASACNLLGLEVQDLDE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 79 NDIQLGHKESVMDTARVLGRLFDGIQFR---------GFSQDTVEKLAQ--YSGV----PVWNGLTDDY-HPTQILADLM 142
Cdd:PRK07200 94 GKSQIAHGETVRETANMISFMADVIGIRddmyigkgnAYMREVGAAVDDgyKQGVlpqrPTLVNLQCDIdHPTQSMADLL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 143 TIKEQFG---TLKG----LTFVYAGD-GRNNMANSLMIGC-SKMGIHYTLFAPK--ELWPKenLMKSCKEYAELSGSTIT 211
Cdd:PRK07200 174 HLIEHFGgleNLKGkkiaMTWAYSPSyGKPLSVPQGIIGLmTRFGMDVTLAHPEgyDLMPE--VVEVAKKNAKASGGSFR 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 212 LSEDLA-CVKGADIIYSDVWCS----------MGEED----KAAERvKLL------KPYQVNATLMAKTEKDNTIFLHCL 270
Cdd:PRK07200 252 QVNSMEeAFKDADIVYPKSWAPykvmeertelYRAGDhegiKALEK-ELLaqnaqhKDWHCTEEMMKLTKDGKALYMHCL 330
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1308681316 271 PA------VKGNEVTEEVFEKHARIIFDQAENRMHTIKAVMVA 307
Cdd:PRK07200 331 PAdisgvsCKEGEVTESVFDRYRIALYKEASWKPYIIAAMIFL 373
|
|
| PLN02527 |
PLN02527 |
aspartate carbamoyltransferase |
7-308 |
4.01e-18 |
|
aspartate carbamoyltransferase
Pssm-ID: 178142 [Multi-domain] Cd Length: 306 Bit Score: 82.87 E-value: 4.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 7 SLLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGG---HPEYLGkNDIQL 83
Cdd:PLN02527 2 DVIEAQQFDREMLELLFEVAREMEKVERGSPGSQMLKGYLMATLFYEPSTRTRLSFESAMKRLGGevlTTENAG-EFSSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 84 GHKESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWN-GLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAGDG 162
Cdd:PLN02527 81 AKGETLEDTIRTVEGYSDIIVLRHFESGAARRAAATAEIPVINaGDGPGQHPTQALLDVYTIQREIGRLDGIKVGLVGDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 163 RNN-MANSL-MIGCSKMGIHYTLFAPKELWPKENLmkscKEYAELSGSTITLSEDLACV-KGADIIYSdvwcSMGEEDKA 239
Cdd:PLN02527 161 ANGrTVRSLaYLLAKYEDVKIYFVAPDVVKMKDDI----KDYLTSKGVEWEESSDLMEVaSKCDVLYQ----TRIQRERF 232
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1308681316 240 AERVKLLKP----YQVNATLMAKTEKDnTIFLHCLPAVkgNEVTEEVFEKHARIIFDQAEN----RMHTIKAVMVAT 308
Cdd:PLN02527 233 GERIDLYEAargkYIVDKKVMDVLPKH-AVVMHPLPRL--DEITTDVDSDPRAAYFRQAKNglfiRMALLKLLLGGW 306
|
|
| PRK11891 |
PRK11891 |
aspartate carbamoyltransferase; Provisional |
8-311 |
1.17e-15 |
|
aspartate carbamoyltransferase; Provisional
Pssm-ID: 183362 [Multi-domain] Cd Length: 429 Bit Score: 76.83 E-value: 1.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 8 LLTLKDFSPQEIDYLLELAMDLKAKKRMGIRGDLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHP-EYLGKNDIQLGHK 86
Cdd:PRK11891 90 LLSVDQFSRDSVEALFRVADVMQPIARRQKISRVLEGAVLGNLFFEASTRTRVSFGAAFCRLGGSVcDTTGFTFSSMAKG 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 87 ESVMDTARVLGRLFDGIQFRGFSQDTVEKLAQYSGVPVWN-GLTDDYHPTQILADLMTIKEQFG----TLKGLTFVYAGD 161
Cdd:PRK11891 170 ESIYDTSRVMSGYVDALVIRHPEQGSVAEFARATNLPVINgGDGPGEHPSQALLDLYTIQREFSrlgkIVDGAHIALVGD 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 162 ---GRNnmANSLMigcsKM-----GIHYTLFAPKELwpkeNLMKSCKEYAELSGSTITLSEDLA-CVKGADIIYSdvwCS 232
Cdd:PRK11891 250 lkyGRT--VHSLV----KLlalyrGLKFTLVSPPTL----EMPAYIVEQISRNGHVIEQTDDLAaGLRGADVVYA---TR 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 233 MGEEDKAAERVKLLKP-YQVNATLMAKTEKDNTIFLHCLPAVK---GNEVTEEVFEKHARIIFDQAEN----RMhTIKAV 304
Cdd:PRK11891 317 IQKERFADESFEGYTPdFQINQALVDAVCKPDTLIMHPLPRDSrpgANDLSTDLNRDPRLAIFRQTDNgipvRM-AIFAV 395
|
....*..
gi 1308681316 305 MVATAGK 311
Cdd:PRK11891 396 LLGVENL 402
|
|
| pyrB |
PRK13814 |
aspartate carbamoyltransferase; |
40-305 |
5.33e-13 |
|
aspartate carbamoyltransferase;
Pssm-ID: 139876 [Multi-domain] Cd Length: 310 Bit Score: 68.21 E-value: 5.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 40 DLLCGKNVALIFEKPSTRTRCAFTVGCVDEGGHPEYLGKNDIQLGHKESVMDTARVLGRLfdGIQF---RGFSQDTVEKL 116
Cdd:PRK13814 41 ETLKGHVVANLFFEPSTRTRNSFEIAAKRLGAMVLNPNLKISAISKGETLFDTIKTLEAM--GVYFfivRHSENETPEQI 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 117 AQY--SGVPVWNGLTDDYHPTQILADLMTIKEQFGTLKGLTFVYAGDGRNN-MANSLMIGCSKMGI-HYTLFAPKELWPK 192
Cdd:PRK13814 119 AKQlsSGVVINAGDGNHQHPSQALIDLMTIKQHKPHWNKLCVTIIGDIRHSrVANSLMDGLVTMGVpEIRLVGPSSLLPD 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308681316 193 ENLMKSCKEYAELSGStitlsedlacvkgadIIYSDVWCSMGEEDKAAERVKLLKPYQVNATLMAK---TEKDNTIFLHC 269
Cdd:PRK13814 199 KVGNDSIKKFTELKPS---------------LLNSDVIVTLRLQKERHDNSVDIDAFRGSFRLTPEklySAKPDAIVMHP 263
|
250 260 270
....*....|....*....|....*....|....*.
gi 1308681316 270 LPAVKGNEVTEEVFEKHARIIFDQAENRMHTIKAVM 305
Cdd:PRK13814 264 GPVNREVEINSDVADNQQSVILQQVRNGVAMRMAVL 299
|
|
| |
