NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1308587778|gb|PKL86977|]
View 

preprotein translocase subunit YajC [Ignavibacteriae bacterium HGW-Ignavibacteriae-1]

Protein Classification

preprotein translocase subunit YajC( domain architecture ID 10004811)

preprotein translocase subunit YajC forms a complex with SecD and SecF and plays a role in stabilizing and regulating secretion through the SecYEG transmembrane complex via SecA

Gene Symbol:  yajC
Gene Ontology:  GO:0015031|GO:0005886
PubMed:  20801097|10066476

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 14-95 6.20e-40

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 441467  Cd Length: 102  Bit Score: 127.60  E-value: 6.20e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778  14 MMSMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIAN 93
Cdd:COG1862    13 GLMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDDTVTLEIADGVKVKVERSAIAR 92


                  ..
gi 1308587778  94 KL 95
Cdd:COG1862    93 VL 94
 
Name Accession Description Interval E-value
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 14-95 6.20e-40

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441467  Cd Length: 102  Bit Score: 127.60  E-value: 6.20e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778  14 MMSMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIAN 93
Cdd:COG1862    13 GLMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDDTVTLEIADGVKVKVERSAIAR 92


                  ..
gi 1308587778  94 KL 95
Cdd:COG1862    93 VL 94
YajC pfam02699
Preprotein translocase subunit; See.
 16-92 2.38e-35

Preprotein translocase subunit; See.


Pssm-ID: 460655  Cd Length: 78  Bit Score: 115.19  E-value: 2.38e-35
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1308587778 16 SMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIA 92
Cdd:pfam02699  1 SSLLPLVLIFVIFYFLMIRPQQKRQKEHQEMLDSLKKGDEVVTIGGIHGKVVKVDDDEVTLEIAAGVKIKVERSAIA 77
yajC PRK05585
preprotein translocase subunit YajC; Validated
 14-95 2.06e-34

preprotein translocase subunit YajC; Validated


Pssm-ID: 235518  Cd Length: 106  Bit Score: 113.45  E-value: 2.06e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778  14 MMSMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIAN 93
Cdd:PRK05585   17 GLSSLLPLVVFFAIFYFLIIRPQQKRQKEHKKMLSSLAKGDEVVTNGGIIGKVTKVSEDFVIIELNDDTEIKIQKSAIAA 96


                  ..
gi 1308587778  94 KL 95
Cdd:PRK05585   97 VL 98
yajC TIGR00739
preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase ...
 15-95 1.92e-27

preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase in Escherichia coli, it is not essential for viability or protein secretion. The N-terminus region contains a predicted membrane-spanning region followed by a region consisting almost entirely of residues with charged (acidic, basic, or zwitterionic) side chains. This small protein is about 100 residues in length, and is restricted to bacteria; however, this protein is absent from some lineages, including spirochetes and Mycoplasmas. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273243  Cd Length: 84  Bit Score: 95.45  E-value: 1.92e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778 15 MSMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIANK 94
Cdd:TIGR00739  3 LTTLLPLVLIFLIFYFLIIRPQRKRRKAHKKLIESLKKGDKVLTIGGIIGTVTKIAENTIVIELNDNTEITFSKNAIVEV 82


                 .
gi 1308587778 95 L 95
Cdd:TIGR00739 83 L 83
 
Name Accession Description Interval E-value
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 14-95 6.20e-40

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441467  Cd Length: 102  Bit Score: 127.60  E-value: 6.20e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778  14 MMSMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIAN 93
Cdd:COG1862    13 GLMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDDTVTLEIADGVKVKVERSAIAR 92


                  ..
gi 1308587778  94 KL 95
Cdd:COG1862    93 VL 94
YajC pfam02699
Preprotein translocase subunit; See.
 16-92 2.38e-35

Preprotein translocase subunit; See.


Pssm-ID: 460655  Cd Length: 78  Bit Score: 115.19  E-value: 2.38e-35
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1308587778 16 SMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIA 92
Cdd:pfam02699  1 SSLLPLVLIFVIFYFLMIRPQQKRQKEHQEMLDSLKKGDEVVTIGGIHGKVVKVDDDEVTLEIAAGVKIKVERSAIA 77
yajC PRK05585
preprotein translocase subunit YajC; Validated
 14-95 2.06e-34

preprotein translocase subunit YajC; Validated


Pssm-ID: 235518  Cd Length: 106  Bit Score: 113.45  E-value: 2.06e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778  14 MMSMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIAN 93
Cdd:PRK05585   17 GLSSLLPLVVFFAIFYFLIIRPQQKRQKEHKKMLSSLAKGDEVVTNGGIIGKVTKVSEDFVIIELNDDTEIKIQKSAIAA 96


                  ..
gi 1308587778  94 KL 95
Cdd:PRK05585   97 VL 98
yajC TIGR00739
preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase ...
 15-95 1.92e-27

preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase in Escherichia coli, it is not essential for viability or protein secretion. The N-terminus region contains a predicted membrane-spanning region followed by a region consisting almost entirely of residues with charged (acidic, basic, or zwitterionic) side chains. This small protein is about 100 residues in length, and is restricted to bacteria; however, this protein is absent from some lineages, including spirochetes and Mycoplasmas. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273243  Cd Length: 84  Bit Score: 95.45  E-value: 1.92e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778 15 MSMLLMFAVVIAIMYFMMIRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKASIANK 94
Cdd:TIGR00739  3 LTTLLPLVLIFLIFYFLIIRPQRKRRKAHKKLIESLKKGDKVLTIGGIIGTVTKIAENTIVIELNDNTEITFSKNAIVEV 82


                 .
gi 1308587778 95 L 95
Cdd:TIGR00739 83 L 83
yajC PRK06531
preprotein translocase subunit YajC; Validated
 14-91 9.56e-14

preprotein translocase subunit YajC; Validated


Pssm-ID: 235822  Cd Length: 113  Bit Score: 61.36  E-value: 9.56e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778  14 MMSMLLMFAVVIAIMYFMMiRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTV--TDSDDTTFTLQIaDNVKVKFEKASI 91
Cdd:PRK06531    2 GIPTIIMFVVMLGLIFFMQ-RQQKKQAQERQNQLNAIQKGDEVVTIGGLYGTVdeVDTEAKTIVLDV-DGVYLTFELAAI 79
yajC PRK05886
preprotein translocase subunit YajC; Validated
 14-95 1.31e-05

preprotein translocase subunit YajC; Validated


Pssm-ID: 235636  Cd Length: 109  Bit Score: 40.19  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1308587778  14 MMSMLLMFAVVI---AIMYFMMiRPQQKRQKEHQNMLSNIRKGDRVVTTAGMHGTVTDSDDTTFTLQIADNVKVKFEKAS 90
Cdd:PRK05886    1 MESLVLFLPFLLimgGFMYFAS-RRQRKAMQATIDLHESLQPGDRVHTTSGLQATIVGITDDTVDLEIAPGVVTTWMKLA 79


                  ....*
gi 1308587778  91 IANKL 95
Cdd:PRK05886   80 VRDRI 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH