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Conserved domains on  [gi|1307908974|gb|AUE05994|]
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putative membrane spanning protein [Bifidobacterium breve]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 11445445)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  12369917

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
73-191 5.94e-13

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


:

Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 65.04  E-value: 5.94e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307908974  73 SIEVDDGVTLPAILREPiDAPGSRPACLFIHGSGTSGAEDFGDIANAMASAGIVTLVPAKRNDNYTVLHRDYQRFaREYS 152
Cdd:COG1506     1 TFKSADGTTLPGWLYLP-ADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDEV-DDVL 78
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1307908974 153 SSLDVLRSTAGVDPAKTGIYAESEGTWISTILASKRQDI 191
Cdd:COG1506    79 AAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDR 117
 
Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
73-191 5.94e-13

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 65.04  E-value: 5.94e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307908974  73 SIEVDDGVTLPAILREPiDAPGSRPACLFIHGSGTSGAEDFGDIANAMASAGIVTLVPAKRNDNYTVLHRDYQRFaREYS 152
Cdd:COG1506     1 TFKSADGTTLPGWLYLP-ADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDEV-DDVL 78
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1307908974 153 SSLDVLRSTAGVDPAKTGIYAESEGTWISTILASKRQDI 191
Cdd:COG1506    79 AAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDR 117
 
Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
73-191 5.94e-13

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 65.04  E-value: 5.94e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307908974  73 SIEVDDGVTLPAILREPiDAPGSRPACLFIHGSGTSGAEDFGDIANAMASAGIVTLVPAKRNDNYTVLHRDYQRFaREYS 152
Cdd:COG1506     1 TFKSADGTTLPGWLYLP-ADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDEV-DDVL 78
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1307908974 153 SSLDVLRSTAGVDPAKTGIYAESEGTWISTILASKRQDI 191
Cdd:COG1506    79 AAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDR 117
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
70-193 7.31e-09

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 53.77  E-value: 7.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307908974  70 TKLSIEVDDGVTLPAILREPIDAPGSRPACLFIHGSGTSgAEDFGDIANAMASAGIVTLVPAKRN----DNYTVLHRDYQ 145
Cdd:COG1073    11 EDVTFKSRDGIKLAGDLYLPAGASKKYPAVVVAHGNGGV-KEQRALYAQRLAELGFNVLAFDYRGygesEGEPREEGSPE 89
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1307908974 146 RfaREYSSSLDVLRSTAGVDPAKTGIYAESEGTWISTILASKRQDIAF 193
Cdd:COG1073    90 R--RDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRVKA 135
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
68-192 8.20e-07

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 47.65  E-value: 8.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307908974  68 RETKLSIEVDDGVTLPAILREPiDAPGSRPACLFIHGSGtSGAEDFGDIANAMASAGIVTLVP-----AKRNDN-----Y 137
Cdd:COG0412     2 TTETVTIPTPDGVTLPGYLARP-AGGGPRPGVVVLHEIF-GLNPHIRDVARRLAAAGYVVLAPdlygrGGPGDDpdearA 79
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1307908974 138 TVLHRDYQRFAREYSSSLDVLRSTAGVDPAKTGIYAESEGTWISTILASKRQDIA 192
Cdd:COG0412    80 LMGALDPELLAADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPDLA 134
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
82-192 5.99e-04

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 39.54  E-value: 5.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307908974  82 LPAILREPIDAPGSRPACLFIHGSgTSGAEDFGDIANAMASAGIVTLVP------AKRNDNYTVLHRDYQRFAREyssSL 155
Cdd:COG1647     1 MKILGAEPFFLEGGRKGVLLLHGF-TGSPAEMRPLAEALAKAGYTVYAPrlpghgTSPEDLLKTTWEDWLEDVEE---AY 76
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1307908974 156 DVLRstAGVDpaKTGIYAESEGTWISTILASKRQDIA 192
Cdd:COG1647    77 EILK--AGYD--KVIVIGLSMGGLLALLLAARYPDVA 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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