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Conserved domains on  [gi|1281035632|ref|XP_023002344|]
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molybdate transporter 1 [Cucurbita maxima]

Protein Classification

putative sulfate/molybdate transporter( domain architecture ID 11246611)

putative sulfate/molybdate transporter belonging to the major facilitator superfamily (MFS), similar to Arabidopsis thaliana MOT2, which is required for vacuolar molybdate export from leaves to seeds during plant senescence

CATH:  1.20.1250.20
Gene Ontology:  GO:0016020|GO:0055085|GO:0022857
PubMed:  26758938|26098515|26234418
SCOP:  3000310
TCDB:  2.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MFS_MOT1 pfam16983
Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. ...
 45-160 2.47e-38

Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. Molybdenum is an essential element that is taken up into the cell in the oxyanion molybdate. Molybdenum is used in the form of molybdopterin-cofactor, which participates in the active site of enzymes involved in key reactions of carbon, nitrogen, and sulfur metabolism.


:

Pssm-ID: 465330 [Multi-domain]  Cd Length: 115  Bit Score: 134.87  E-value: 2.47e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281035632  45 AELNGAMGDLGTYIPIVLSLTLSKDLNLGTTLIFTGIYNIITGLIYGVPMPVQPMKSIAAAALADPEFGvAEIMAAGILT 124
Cdd:pfam16983   1 GELSGALGQLGTLLPLVIALALLAGDSPTSLLLSVGLMNLLTGLFGGMPMCVQPMKHGAGGLAAQYRFG-ARTGAAGILL 79

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1281035632 125 GGILFFLGATGLMHLVYKFIPLPVVRGIQLAQGLSF 160
Cdd:pfam16983  80 GLVLLLLGLTGLLVRLLRLIPLPVLGGIQLGAGLEL 115
MFS_MOT1 pfam16983
Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. ...
 278-397 7.73e-20

Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. Molybdenum is an essential element that is taken up into the cell in the oxyanion molybdate. Molybdenum is used in the form of molybdopterin-cofactor, which participates in the active site of enzymes involved in key reactions of carbon, nitrogen, and sulfur metabolism.


:

Pssm-ID: 465330 [Multi-domain]  Cd Length: 115  Bit Score: 84.41  E-value: 7.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281035632 278 GFIKGTIPQLPlSILNSVIAVCKLSMDlfpgrvfTVTSLSMTVGLMNIIGCWFGGVPTC-----HGAGGLAGQYKFGGRS 352
Cdd:pfam16983   1 GELSGALGQLG-TLLPLVIALALLAGD-------SPTSLLLSVGLMNLLTGLFGGMPMCvqpmkHGAGGLAAQYRFGART 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1281035632 353 GACVALLGAAKLLLGLVLGSSLakVLNRYPVGILGVLLLFAGVEL 397
Cdd:pfam16983  73 GAAGILLGLVLLLLGLTGLLVR--LLRLIPLPVLGGIQLGAGLEL 115
 
Name Accession Description Interval E-value
MFS_MOT1 pfam16983
Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. ...
 45-160 2.47e-38

Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. Molybdenum is an essential element that is taken up into the cell in the oxyanion molybdate. Molybdenum is used in the form of molybdopterin-cofactor, which participates in the active site of enzymes involved in key reactions of carbon, nitrogen, and sulfur metabolism.


Pssm-ID: 465330 [Multi-domain]  Cd Length: 115  Bit Score: 134.87  E-value: 2.47e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281035632  45 AELNGAMGDLGTYIPIVLSLTLSKDLNLGTTLIFTGIYNIITGLIYGVPMPVQPMKSIAAAALADPEFGvAEIMAAGILT 124
Cdd:pfam16983   1 GELSGALGQLGTLLPLVIALALLAGDSPTSLLLSVGLMNLLTGLFGGMPMCVQPMKHGAGGLAAQYRFG-ARTGAAGILL 79

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1281035632 125 GGILFFLGATGLMHLVYKFIPLPVVRGIQLAQGLSF 160
Cdd:pfam16983  80 GLVLLLLGLTGLLVRLLRLIPLPVLGGIQLGAGLEL 115
MFS_MOT1 pfam16983
Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. ...
 278-397 7.73e-20

Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. Molybdenum is an essential element that is taken up into the cell in the oxyanion molybdate. Molybdenum is used in the form of molybdopterin-cofactor, which participates in the active site of enzymes involved in key reactions of carbon, nitrogen, and sulfur metabolism.


Pssm-ID: 465330 [Multi-domain]  Cd Length: 115  Bit Score: 84.41  E-value: 7.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281035632 278 GFIKGTIPQLPlSILNSVIAVCKLSMDlfpgrvfTVTSLSMTVGLMNIIGCWFGGVPTC-----HGAGGLAGQYKFGGRS 352
Cdd:pfam16983   1 GELSGALGQLG-TLLPLVIALALLAGD-------SPTSLLLSVGLMNLLTGLFGGMPMCvqpmkHGAGGLAAQYRFGART 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1281035632 353 GACVALLGAAKLLLGLVLGSSLakVLNRYPVGILGVLLLFAGVEL 397
Cdd:pfam16983  73 GAAGILLGLVLLLLGLTGLLVR--LLRLIPLPVLGGIQLGAGLEL 115
 
Name Accession Description Interval E-value
MFS_MOT1 pfam16983
Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. ...
 45-160 2.47e-38

Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. Molybdenum is an essential element that is taken up into the cell in the oxyanion molybdate. Molybdenum is used in the form of molybdopterin-cofactor, which participates in the active site of enzymes involved in key reactions of carbon, nitrogen, and sulfur metabolism.


Pssm-ID: 465330 [Multi-domain]  Cd Length: 115  Bit Score: 134.87  E-value: 2.47e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281035632  45 AELNGAMGDLGTYIPIVLSLTLSKDLNLGTTLIFTGIYNIITGLIYGVPMPVQPMKSIAAAALADPEFGvAEIMAAGILT 124
Cdd:pfam16983   1 GELSGALGQLGTLLPLVIALALLAGDSPTSLLLSVGLMNLLTGLFGGMPMCVQPMKHGAGGLAAQYRFG-ARTGAAGILL 79

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1281035632 125 GGILFFLGATGLMHLVYKFIPLPVVRGIQLAQGLSF 160
Cdd:pfam16983  80 GLVLLLLGLTGLLVRLLRLIPLPVLGGIQLGAGLEL 115
MFS_MOT1 pfam16983
Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. ...
 278-397 7.73e-20

Molybdate transporter of MFS superfamily; MFS_MOT1 is a family of molybdenate transporters. Molybdenum is an essential element that is taken up into the cell in the oxyanion molybdate. Molybdenum is used in the form of molybdopterin-cofactor, which participates in the active site of enzymes involved in key reactions of carbon, nitrogen, and sulfur metabolism.


Pssm-ID: 465330 [Multi-domain]  Cd Length: 115  Bit Score: 84.41  E-value: 7.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281035632 278 GFIKGTIPQLPlSILNSVIAVCKLSMDlfpgrvfTVTSLSMTVGLMNIIGCWFGGVPTC-----HGAGGLAGQYKFGGRS 352
Cdd:pfam16983   1 GELSGALGQLG-TLLPLVIALALLAGD-------SPTSLLLSVGLMNLLTGLFGGMPMCvqpmkHGAGGLAAQYRFGART 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1281035632 353 GACVALLGAAKLLLGLVLGSSLakVLNRYPVGILGVLLLFAGVEL 397
Cdd:pfam16983  73 GAAGILLGLVLLLLGLTGLLVR--LLRLIPLPVLGGIQLGAGLEL 115
Xan_ur_permease pfam00860
Permease family; This family includes permeases for diverse substrates such as xanthine, ...
 74-168 2.67e-03

Permease family; This family includes permeases for diverse substrates such as xanthine, uracil and vitamin C. However many members of this family are functionally uncharacterized and may transport other substrates. Members of this family have ten predicted transmembrane helices.


Pssm-ID: 395690 [Multi-domain]  Cd Length: 389  Bit Score: 39.97  E-value: 2.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281035632  74 TTLIFTGIYNIITGLIYGVPMPVQPMKSIAA-------AALADPEFGVAEIMAAGILTGGILFFLGATGLMHLVYKFIPL 146
Cdd:pfam00860  42 ATFLASGIGTLLQTLIFGIRLPIYLGSSFAFvtalmiaLGLADWGIALAGLFGAVLVAGVLFTLISFTGLRGRLARLFPP 121

                          90       100
                  ....*....|....*....|..
gi 1281035632 147 PVVRGIQLAQGLSFALTAVKYI 168
Cdd:pfam00860 122 VVTGPVVLLIGLSLAPIAVKGA 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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