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Conserved domains on  [gi|1281001457|ref|XP_022984531|]
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uncharacterized protein LOC111482797 [Cucurbita maxima]

Protein Classification

ribonuclease P Rpr2/Rpp21/SNM1 subunit( domain architecture ID 10513160)

ribonuclease P (RNAse P) Rpr2/Rpp21/SNM1 subunit is a component of RNAse P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends; ribonuclease P protein component 4 is part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends

EC:  3.1.26.5
Gene Ontology:  GO:0046872|GO:0006278|GO:0004526|GO:0030677
PubMed:  21930585|14550630

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rpr2 pfam04032
RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of ...
 45-136 2.76e-13

RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologs. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.


:

Pssm-ID: 427665  Cd Length: 88  Bit Score: 64.63  E-value: 2.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281001457  45 LNHLENLATWASgKASIPSLAAFFGQRLATAAESLAVAPDASL--FTCQRCETILQPGSNCSIRIEKNNAKRRRRqkkcs 122
Cdd:pfam04032   2 LNFLYQAAHLLA-RPGNPELSRRYVSLLRAISKKAVLRLPPSIkrTICKKCGTLLIPGVTCTVRIENKSKGGKKP----- 75

                          90
                  ....*....|....
gi 1281001457 123 nsRQNNVAYYCHHC 136
Cdd:pfam04032  76 --WADVLVYTCLTC 87
 
Name Accession Description Interval E-value
Rpr2 pfam04032
RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of ...
 45-136 2.76e-13

RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologs. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.


Pssm-ID: 427665  Cd Length: 88  Bit Score: 64.63  E-value: 2.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281001457  45 LNHLENLATWASgKASIPSLAAFFGQRLATAAESLAVAPDASL--FTCQRCETILQPGSNCSIRIEKNNAKRRRRqkkcs 122
Cdd:pfam04032   2 LNFLYQAAHLLA-RPGNPELSRRYVSLLRAISKKAVLRLPPSIkrTICKKCGTLLIPGVTCTVRIENKSKGGKKP----- 75

                          90
                  ....*....|....
gi 1281001457 123 nsRQNNVAYYCHHC 136
Cdd:pfam04032  76 --WADVLVYTCLTC 87
 
Name Accession Description Interval E-value
Rpr2 pfam04032
RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of ...
 45-136 2.76e-13

RNAse P Rpr2/Rpp21/SNM1 subunit domain; This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologs. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.


Pssm-ID: 427665  Cd Length: 88  Bit Score: 64.63  E-value: 2.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1281001457  45 LNHLENLATWASgKASIPSLAAFFGQRLATAAESLAVAPDASL--FTCQRCETILQPGSNCSIRIEKNNAKRRRRqkkcs 122
Cdd:pfam04032   2 LNFLYQAAHLLA-RPGNPELSRRYVSLLRAISKKAVLRLPPSIkrTICKKCGTLLIPGVTCTVRIENKSKGGKKP----- 75

                          90
                  ....*....|....
gi 1281001457 123 nsRQNNVAYYCHHC 136
Cdd:pfam04032  76 --WADVLVYTCLTC 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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