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Conserved domains on  [gi|1279778059|ref|XP_022941777|]
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caffeoylshikimate esterase-like [Cucurbita moschata]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 229394)

alpha/beta hydrolase family protein may catalyze the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 7-290 1.28e-120

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member PLN02385:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 349  Bit Score: 350.21  E-value: 1.28e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059   7 EEEFIVNSRGLKLFTCSWVPKNDEPKALVFLCHGYAMECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSFDK 86
Cdd:PLN02385   62 EESYEVNSRGVEIFSKSWLPENSRPKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDD 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  87 VVDDCSSFFTSITEKNENREKKRYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMRPNPLTISFLTKLCKIIP 166
Cdd:PLN02385  142 LVDDVIEHYSKIKGNPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLLP 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 167 TWKIIPTQDIIDIAFKVPEIRKQIRENRYCYKGRPRLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSKQL 246
Cdd:PLN02385  222 KAKLVPQKDLAELAFRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFL 301

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1279778059 247 YDEAVSDDKTLKMYPGMWHGLLYGETPENIDIVFSDIIDWLEKR 290
Cdd:PLN02385  302 YEKASSSDKKLKLYEDAYHSILEGEPDEMIFQVLDDIISWLDSH 345
 
Name Accession Description Interval E-value
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 7-290 1.28e-120

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 350.21  E-value: 1.28e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059   7 EEEFIVNSRGLKLFTCSWVPKNDEPKALVFLCHGYAMECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSFDK 86
Cdd:PLN02385   62 EESYEVNSRGVEIFSKSWLPENSRPKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDD 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  87 VVDDCSSFFTSITEKNENREKKRYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMRPNPLTISFLTKLCKIIP 166
Cdd:PLN02385  142 LVDDVIEHYSKIKGNPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLLP 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 167 TWKIIPTQDIIDIAFKVPEIRKQIRENRYCYKGRPRLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSKQL 246
Cdd:PLN02385  222 KAKLVPQKDLAELAFRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFL 301

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1279778059 247 YDEAVSDDKTLKMYPGMWHGLLYGETPENIDIVFSDIIDWLEKR 290
Cdd:PLN02385  302 YEKASSSDKKLKLYEDAYHSILEGEPDEMIFQVLDDIISWLDSH 345
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 29-268 6.13e-78

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 237.50  E-value: 6.13e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  29 DEPKALVFLCHGYAmECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSFDKVVDDCSSFFTSITEknENREKK 108
Cdd:pfam12146   1 GEPRAVVVLVHGLG-EHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIRE--EHPGLP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 109 RYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMrPNPLTISFLTKLCKIIPTWKIiPTQDIIDIAFKVPEIRK 188
Cdd:pfam12146  78 LFLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRV-PNNLLPDSLSRDPEVVA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 189 QIRENRYCyKGRPRLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSKQLYDEAVSDDKTLKMYPGMWHGLL 268
Cdd:pfam12146 156 AYAADPLV-HGGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELL 234
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
5-289 4.81e-42

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 144.76  E-value: 4.81e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059   5 TYEEEFIVNSRGLKLFTCSWVPKnDEPKALVFLCHGYAmECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSF 84
Cdd:COG2267     2 TRRLVTLPTRDGLRLRGRRWRPA-GSPRGTVVLVHGLG-EHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  85 DKVVDDCSSFFTSITEKnenREKKRYLMGESMGGAVALLVHRKQPDYWDGAILVAPmckiaeDMRPNPLtisfltklckI 164
Cdd:COG2267    80 DDYVDDLRAALDALRAR---PGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAP------AYRADPL----------L 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 165 IPTWKIIptqdiidiafkvpeirkqirenrycykgrprlktghellrISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSK 244
Cdd:COG2267   141 GPSARWL----------------------------------------RALRLAEALARIDVPVLVLHGGADRVVPPEAAR 180

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1279778059 245 QLYdEAVSDDKTLKMYPGMWHGLLYGETPEnidIVFSDIIDWLEK 289
Cdd:COG2267   181 RLA-ARLSPDVELVLLPGARHELLNEPARE---EVLAAILAWLER 221
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 13-288 9.98e-15

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 73.66  E-value: 9.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  13 NSRGLKLFTCSWVPKNdePKALVFLCHGYAMECSITM-------------------------DSSARRLAEEGYGVYGID 67
Cdd:TIGR01607   4 NKDGLLLKTYSWIVKN--AIGIIVLIHGLKSHLRLQFlkinakivnndravlidtdnyyiykDSWIENFNKNGYSVYGLD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  68 YEGHGKSSGLQ---GYVSSFDKVVDDCSSFF-----TSITEKN----------ENREKKR---YLMGESMGGAVALLVHR 126
Cdd:TIGR01607  82 LQGHGESDGLQnlrGHINCFDDLVYDVIQYMnrindSIILENEtksddesydiVNTKENRlpmYIIGLSMGGNIALRLLE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 127 ---KQPDYWD-----GAILVAPMCKIAEDMRPNPLT-----ISFLTKLCKIIPTWKIIPtqdiiDIAF-KVPEIRKQIRE 192
Cdd:TIGR01607 162 llgKSNENNDklnikGCISLSGMISIKSVGSDDSFKfkyfyLPVMNFMSRVFPTFRISK-----KIRYeKSPYVNDIIKF 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 193 NRYCYKGRPRLKTGHELLRISSELEHKLDEV--SVPFLLLHGEDDRVTDRLVSKQLYDEAVSDDKTLKMYPGMWHGLLYG 270
Cdd:TIGR01607 237 DKFRYDGGITFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLEDMDHVITIE 316

                         330
                  ....*....|....*...
gi 1279778059 271 ETPENidiVFSDIIDWLE 288
Cdd:TIGR01607 317 PGNEE---VLKKIIEWIS 331
 
Name Accession Description Interval E-value
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 7-290 1.28e-120

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 350.21  E-value: 1.28e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059   7 EEEFIVNSRGLKLFTCSWVPKNDEPKALVFLCHGYAMECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSFDK 86
Cdd:PLN02385   62 EESYEVNSRGVEIFSKSWLPENSRPKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDD 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  87 VVDDCSSFFTSITEKNENREKKRYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMRPNPLTISFLTKLCKIIP 166
Cdd:PLN02385  142 LVDDVIEHYSKIKGNPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLLP 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 167 TWKIIPTQDIIDIAFKVPEIRKQIRENRYCYKGRPRLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSKQL 246
Cdd:PLN02385  222 KAKLVPQKDLAELAFRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFL 301

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1279778059 247 YDEAVSDDKTLKMYPGMWHGLLYGETPENIDIVFSDIIDWLEKR 290
Cdd:PLN02385  302 YEKASSSDKKLKLYEDAYHSILEGEPDEMIFQVLDDIISWLDSH 345
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 2-290 1.73e-113

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 331.36  E-value: 1.73e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059   2 ENVTYEEEFIVNSRGLKLFTCSWVPKNDE-PKALVFLCHGYAMECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGY 80
Cdd:PLN02298   28 KGIKGSKSFFTSPRGLSLFTRSWLPSSSSpPRALIFMVHGYGNDISWTFQSTAIFLAQMGFACFALDLEGHGRSEGLRAY 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  81 VSSFDKVVDDCSSFFTSITEKNENREKKRYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMRPNPLTISFLTK 160
Cdd:PLN02298  108 VPNVDLVVEDCLSFFNSVKQREEFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAPMCKISDKIRPPWPIPQILTF 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 161 LCKIIPTWKIIPTQDIIDIAFKVPEIRKQIRENRYCYKGRPRLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDR 240
Cdd:PLN02298  188 VARFLPTLAIVPTADLLEKSVKVPAKKIIAKRNPMRYNGKPRLGTVVELLRVTDYLGKKLKDVSIPFIVLHGSADVVTDP 267

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1279778059 241 LVSKQLYDEAVSDDKTLKMYPGMWHGLLYGETPENIDIVFSDIIDWLEKR 290
Cdd:PLN02298  268 DVSRALYEEAKSEDKTIKIYDGMMHSLLFGEPDENIEIVRRDILSWLNER 317
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 29-268 6.13e-78

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 237.50  E-value: 6.13e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  29 DEPKALVFLCHGYAmECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSFDKVVDDCSSFFTSITEknENREKK 108
Cdd:pfam12146   1 GEPRAVVVLVHGLG-EHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIRE--EHPGLP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 109 RYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMrPNPLTISFLTKLCKIIPTWKIiPTQDIIDIAFKVPEIRK 188
Cdd:pfam12146  78 LFLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRV-PNNLLPDSLSRDPEVVA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 189 QIRENRYCyKGRPRLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSKQLYDEAVSDDKTLKMYPGMWHGLL 268
Cdd:pfam12146 156 AYAADPLV-HGGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELL 234
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 14-290 3.77e-46

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 160.44  E-value: 3.77e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  14 SRGLKLFTCSWVPKNDEPKALVFLCHGYAmECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSFDKVVDDCSS 93
Cdd:PLN02652  118 ARRNALFCRSWAPAAGEMRGILIIIHGLN-EHSGRYLHFAKQLTSCGFGVYAMDWIGHGGSDGLHGYVPSLDYVVEDTEA 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  94 FFTSIteKNENREKKRYLMGESMGGAVAL--LVHRKQPDYWDGAILVAPMCKIaedmRP-NPLTISFLTKLCKIIPTWKI 170
Cdd:PLN02652  197 FLEKI--RSENPGVPCFLFGHSTGGAVVLkaASYPSIEDKLEGIVLTSPALRV----KPaHPIVGAVAPIFSLVAPRFQF 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 171 -------IPTQdiidiafKVPEIRKQIRENRYCYKGRPRLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDRLVS 243
Cdd:PLN02652  271 kgankrgIPVS-------RDPAALLAKYSDPLVYTGPIRVRTGHEILRISSYLTRNFKSVTVPFMVLHGTADRVTDPLAS 343

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1279778059 244 KQLYDEAVSDDKTLKMYPGMWHGLLYgeTPENiDIVFSDIIDWLEKR 290
Cdd:PLN02652  344 QDLYNEAASRHKDIKLYDGFLHDLLF--EPER-EEVGRDIIDWMEKR 387
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
5-289 4.81e-42

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 144.76  E-value: 4.81e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059   5 TYEEEFIVNSRGLKLFTCSWVPKnDEPKALVFLCHGYAmECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSF 84
Cdd:COG2267     2 TRRLVTLPTRDGLRLRGRRWRPA-GSPRGTVVLVHGLG-EHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  85 DKVVDDCSSFFTSITEKnenREKKRYLMGESMGGAVALLVHRKQPDYWDGAILVAPmckiaeDMRPNPLtisfltklckI 164
Cdd:COG2267    80 DDYVDDLRAALDALRAR---PGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAP------AYRADPL----------L 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 165 IPTWKIIptqdiidiafkvpeirkqirenrycykgrprlktghellrISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSK 244
Cdd:COG2267   141 GPSARWL----------------------------------------RALRLAEALARIDVPVLVLHGGADRVVPPEAAR 180

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1279778059 245 QLYdEAVSDDKTLKMYPGMWHGLLYGETPEnidIVFSDIIDWLEK 289
Cdd:COG2267   181 RLA-ARLSPDVELVLLPGARHELLNEPARE---EVLAAILAWLER 221
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
35-289 9.91e-29

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 110.42  E-value: 9.91e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  35 VFLCHGYaMECSITMDSSARRLAEEGYGVYGIDYEGHGKS------SGLQGYVSSFDKVVDDCSSFFTSIteknenrekk 108
Cdd:COG1647    18 VLLLHGF-TGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSpedllkTTWEDWLEDVEEAYEILKAGYDKV---------- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 109 rYLMGESMGGAVALLVHRKQPDYwDGAILVAPMCKIAedmRPNPLTISFLTKLCKIIPTWKIIPtqdiidiafkvpeirK 188
Cdd:COG1647    87 -IVIGLSMGGLLALLLAARYPDV-AGLVLLSPALKID---DPSAPLLPLLKYLARSLRGIGSDI---------------E 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 189 QIRENRYCYKGRPrLKTGHELLRISSELEHKLDEVSVPFLLLHGEDDRVTDRLVSKQLYDEAVSDDKTLKMYPGMWHGLL 268
Cdd:COG1647   147 DPEVAEYAYDRTP-LRALAELQRLIREVRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVWLEDSGHVIT 225

                         250       260
                  ....*....|....*....|.
gi 1279778059 269 YGetpENIDIVFSDIIDWLEK 289
Cdd:COG1647   226 LD---KDREEVAEEILDFLER 243
PHA02857 PHA02857
monoglyceride lipase; Provisional
 31-290 7.67e-27

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 106.51  E-value: 7.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  31 PKALVFLCHGyAMECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGYVSSFDKVVDDCSSFFTSITEKNENreKKRY 110
Cdd:PHA02857   24 PKALVFISHG-AGEHSGRYEELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYVRDVVQHVVTIKSTYPG--VPVF 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 111 LMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMRPNPLTisflTKLCKIIPTWKIIPTqdiidiaFKVPEIRKQI 190
Cdd:PHA02857  101 LLGHSMGATISILAAYKNPNLFTAMILMSPLVNAEAVPRLNLLA----AKLMGIFYPNKIVGK-------LCPESVSRDM 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 191 RENrYCYKGRP-----RLKTG--HELLRISSELEHKLDEVSVPFLLLHGEDDRVTDrlVSKQLY-DEAVSDDKTLKMYPG 262
Cdd:PHA02857  170 DEV-YKYQYDPlvnheKIKAGfaSQVLKATNKVRKIIPKIKTPILILQGTNNEISD--VSGAYYfMQHANCNREIKIYEG 246

                         250       260
                  ....*....|....*....|....*...
gi 1279778059 263 MWHGlLYGETPENIDIVFSDIIDWLEKR 290
Cdd:PHA02857  247 AKHH-LHKETDEVKKSVMKEIETWIFNR 273
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
25-289 7.81e-27

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 105.10  E-value: 7.81e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  25 VPKNDEPKALVFLCHGYAMECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQGyvssfDKVVDDCSSFFTSITEKNEN 104
Cdd:COG1506    16 LPADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWG-----GDEVDDVLAAIDYLAARPYV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 105 REKKRYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCkiaeDMRpnpltiSFLTKLCKIIPTWKIIPTQDIidiafkvp 184
Cdd:COG1506    91 DPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVS----DLR------SYYGTTREYTERLMGGPWEDP-------- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 185 eirkqirenrycykgrprlktghELLRISSELEHkLDEVSVPFLLLHGEDDRVTDRLVSKQLYDEAVS--DDKTLKMYPG 262
Cdd:COG1506   153 -----------------------EAYAARSPLAY-ADKLKTPLLLIHGEADDRVPPEQAERLYEALKKagKPVELLVYPG 208

                         250       260
                  ....*....|....*....|....*..
gi 1279778059 263 MWHGLLYGETPEnidiVFSDIIDWLEK 289
Cdd:COG1506   209 EGHGFSGAGAPD----YLERILDFLDR 231
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 1-289 3.03e-26

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 104.23  E-value: 3.03e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059   1 MENVTYEEEFIVNSRGLKLFTCSWVPKNDEPK-ALVFLCHGYAmECSITMDSSARRLAEEGYGVYGIDYEGHGKSSGLQG 79
Cdd:COG1073     5 SDKVNKEDVTFKSRDGIKLAGDLYLPAGASKKyPAVVVAHGNG-GVKEQRALYAQRLAELGFNVLAFDYRGYGESEGEPR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  80 YVSSFDKvvDDCSSFFTSITEKNENREKKRYLMGESMGGAVALLVHRKQPDYwDGAILVAPMCKIAE--DMRpnpltisf 157
Cdd:COG1073    84 EEGSPER--RDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRV-KAVILDSPFTSLEDlaAQR-------- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 158 ltklckiiptWKIIPTQDIIDIAFkvpeirkqirenrycykgRPRLKTGhELLRISSELEHKLDEVSVPFLLLHGEDDRV 237
Cdd:COG1073   153 ----------AKEARGAYLPGVPY------------------LPNVRLA-SLLNDEFDPLAKIEKISRPLLFIHGEKDEA 203

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279778059 238 TDRLVSKQLYdEAVSDDKTLKMYPGMWHGLLYGETPEnidIVFSDIIDWLEK 289
Cdd:COG1073   204 VPFYMSEDLY-EAAAEPKELLIVPGAGHVDLYDRPEE---EYFDKLAEFFKK 251
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 13-288 9.98e-15

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 73.66  E-value: 9.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  13 NSRGLKLFTCSWVPKNdePKALVFLCHGYAMECSITM-------------------------DSSARRLAEEGYGVYGID 67
Cdd:TIGR01607   4 NKDGLLLKTYSWIVKN--AIGIIVLIHGLKSHLRLQFlkinakivnndravlidtdnyyiykDSWIENFNKNGYSVYGLD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  68 YEGHGKSSGLQ---GYVSSFDKVVDDCSSFF-----TSITEKN----------ENREKKR---YLMGESMGGAVALLVHR 126
Cdd:TIGR01607  82 LQGHGESDGLQnlrGHINCFDDLVYDVIQYMnrindSIILENEtksddesydiVNTKENRlpmYIIGLSMGGNIALRLLE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 127 ---KQPDYWD-----GAILVAPMCKIAEDMRPNPLT-----ISFLTKLCKIIPTWKIIPtqdiiDIAF-KVPEIRKQIRE 192
Cdd:TIGR01607 162 llgKSNENNDklnikGCISLSGMISIKSVGSDDSFKfkyfyLPVMNFMSRVFPTFRISK-----KIRYeKSPYVNDIIKF 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 193 NRYCYKGRPRLKTGHELLRISSELEHKLDEV--SVPFLLLHGEDDRVTDRLVSKQLYDEAVSDDKTLKMYPGMWHGLLYG 270
Cdd:TIGR01607 237 DKFRYDGGITFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLEDMDHVITIE 316

                         330
                  ....*....|....*...
gi 1279778059 271 ETPENidiVFSDIIDWLE 288
Cdd:TIGR01607 317 PGNEE---VLKKIIEWIS 331
PRK10749 PRK10749
lysophospholipase L2; Provisional
 60-239 3.00e-14

lysophospholipase L2; Provisional


Pssm-ID: 182697  Cd Length: 330  Bit Score: 71.95  E-value: 3.00e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  60 GYGVYGIDYEGHGKSSGL-----QGYVSSFDKVVDDCSSFFTsiTEKNENREKKRYLMGESMGGAVALLVHRKQPDYWDG 134
Cdd:PRK10749   81 GYDVLIIDHRGQGRSGRLlddphRGHVERFNDYVDDLAAFWQ--QEIQPGPYRKRYALAHSMGGAILTLFLQRHPGVFDA 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 135 AILVAPMCKIAEDMrpnpltisfltklckiiPTWKiipTQDIIDIAFKVPEIRK--------------------QIREnR 194
Cdd:PRK10749  159 IALCAPMFGIVLPL-----------------PSWM---ARRILNWAEGHPRIRDgyaigtgrwrplpfainvltHSRE-R 217

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1279778059 195 YC-----YKGRPRLKTG----H---ELLRISSELEHKLDEVSVPFLLLHGEDDRVTD 239
Cdd:PRK10749  218 YRrnlrfYADDPELRVGgptyHwvrESILAGEQVLAGAGDITTPLLLLQAEEERVVD 274
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 29-290 5.46e-14

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 69.64  E-value: 5.46e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  29 DEPKALVFLcHGYAMeCSITMDSSARRLAEeGYGVYGIDYEGHGKSSGLQGYVSsFDKVVDDCSSFFTSIteknenREKK 108
Cdd:COG0596    21 PDGPPVVLL-HGLPG-SSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYT-LDDLADDLAALLDAL------GLER 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 109 RYLMGESMGGAVALLVHRKQPDYWDGAILVAPMCKIAEDMRPNPltisfltklckiiptwkiiptqdiidiAFKVPEIRK 188
Cdd:COG0596    91 VVLVGHSMGGMVALELAARHPERVAGLVLVDEVLAALAEPLRRP---------------------------GLAPEALAA 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 189 QIRENRycykgrprlktghellriSSELEHKLDEVSVPFLLLHGEDDRVTDRLVSKQLYDEAvsDDKTLKMYPGMWHGLL 268
Cdd:COG0596   144 LLRALA------------------RTDLRERLARITVPTLVIWGEKDPIVPPALARRLAELL--PNAELVVLPGAGHFPP 203

                         250       260
                  ....*....|....*....|..
gi 1279778059 269 YgetpENIDIVFSDIIDWLEKR 290
Cdd:COG0596   204 L----EQPEAFAAALRDFLARL 221
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 34-246 1.90e-06

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 48.27  E-value: 1.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  34 LVFLCHGYAMecsiTMDSS---ARRLAEEGYGVYGIDYEGHGKSSGLqgyVSSFDKVVDDCSSFFTSITEKNENreKKRY 110
Cdd:pfam00561   2 PVLLLHGLPG----SSDLWrklAPALARDGFRVIALDLRGFGKSSRP---KAQDDYRTDDLAEDLEYILEALGL--EKVN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 111 LMGESMGGAVALLVHRKQPDYWDGAILVAPmckiaedMRPNPLTISFLTKLCKIIPTW------KIIPTQDIIDIAFKVP 184
Cdd:pfam00561  73 LVGHSMGGLIALAYAAKYPDRVKALVLLGA-------LDPPHELDEADRFILALFPGFfdgfvaDFAPNPLGRLVAKLLA 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1279778059 185 EIRKQIRE-------NRYCYKGRPRLKTG------HELLRISSELEHK-LDEVSVPFLLLHGEDDRVTDRLVSKQL 246
Cdd:pfam00561 146 LLLLRLRLlkalpllNKRFPSGDYALAKSlvtgalLFIETWSTELRAKfLGRLDEPTLIIWGDQDPLVPPQALEKL 221
COG2945 COG2945
Alpha/beta superfamily hydrolase [General function prediction only];
29-140 2.43e-04

Alpha/beta superfamily hydrolase [General function prediction only];


Pssm-ID: 442188 [Multi-domain]  Cd Length: 201  Bit Score: 41.30  E-value: 2.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  29 DEPKALVFLCH-----GYamecsiTMDSS-----ARRLAEEGYGVYGIDYEGHGKSSGlqgyvsSFDK----------VV 88
Cdd:COG2945    20 GPPRGVALILHphplfGG------TMDNKvvytlARALVAAGFAVLRFNFRGVGRSEG------EFDEgrgelddaaaAL 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279778059  89 DDCssfftsitekNENREKKRYLMGESMGGAVALLVHRKQPDYwDGAILVAP 140
Cdd:COG2945    88 DWL----------RAQNPLPLWLAGFSFGAYVALQLAMRLPEV-EGLILVAP 128
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 35-268 2.47e-04

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 41.69  E-value: 2.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  35 VFLCHGyAMECSITMdssaRRLAEEGYGVYGIDYEGHGKSSGLQgyvSSFDKVvDDCSSFFTSITEKnenreKKRYLMGE 114
Cdd:pfam12697   1 VVLVHG-AGLSAAPL----AALLAAGVAVLAPDLPGHGSSSPPP---LDLADL-ADLAALLDELGAA-----RPVVLVGH 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 115 SMGGAVALlvhRKQPDYWDGAILVAPMCKIAEDMRPNPLTISFLTKLcKIIPTW--KIIPTQDIIDIAFKVPEIRKQIRE 192
Cdd:pfam12697  67 SLGGAVAL---AAAAAALVVGVLVAPLAAPPGLLAALLALLARLGAA-LAAPAWlaAESLARGFLDDLPADAEWAAALAR 142

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1279778059 193 NRYcYKGRPRLKTGHELLRIsselehkldevsVPFLLLHGEDDRVTDRLVSKQLydeAVSDDKTLKMYPGMWHGLL 268
Cdd:pfam12697 143 LAA-LLAALALLPLAAWRDL------------PVPVLVLAEEDRLVPELAQRLL---AALAGARLVVLPGAGHLPL 202
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
26-290 5.25e-04

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 40.63  E-value: 5.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  26 PKNDEPKALVFLCHG--YAMECSITMDSSARRLAEE-GYGVYGIDY----EGHgkssglqgyvssFDKVVDDCSSFFTSI 98
Cdd:COG0657     7 AGAKGPLPVVVYFHGggWVSGSKDTHDPLARRLAARaGAAVVSVDYrlapEHP------------FPAALEDAYAALRWL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  99 TEkneNREKKRY------LMGESMGG--AVALLVHRKQPDYW--DGAILVAPMCkiaeDMRPNPLtisfltklckiiptw 168
Cdd:COG0657    75 RA---NAAELGIdpdriaVAGDSAGGhlAAALALRARDRGGPrpAAQVLIYPVL----DLTASPL--------------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 169 kiiptqdiidiafkvpeirkqirenRYCYKGRPrlktghellrisselehkldevsvPFLLLHGEDDRVTDRlvSKQLYD 248
Cdd:COG0657   133 -------------------------RADLAGLP------------------------PTLIVTGEADPLVDE--SEALAA 161

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1279778059 249 --EAVSDDKTLKMYPGMWHGLLYGETPENIDIVFSDIIDWLEKR 290
Cdd:COG0657   162 alRAAGVPVELHVYPGGGHGFGLLAGLPEARAALAEIAAFLRRA 205
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 59-130 6.11e-04

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 41.08  E-value: 6.11e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1279778059  59 EGYGVYGIDYEGHGKSSGLQGyVSSFDKVVDDCSSFF--TSITeknenrekKRYLMGESMGGAVALLVHRKQPD 130
Cdd:PRK14875  156 AGRPVIALDLPGHGASSKAVG-AGSLDELAAAVLAFLdaLGIE--------RAHLVGHSMGGAVALRLAARAPQ 220
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
24-266 1.05e-03

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 39.56  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  24 WVPKNDEPKALVFLCHGYAmecSIT--MDSSARRLAEEGYGVYGIDYEGHGKSSG----LQGYVSSFD--KVVDDCSSFF 95
Cdd:COG0412    21 ARPAGGGPRPGVVVLHEIF---GLNphIRDVARRLAAAGYVVLAPDLYGRGGPGDdpdeARALMGALDpeLLAADLRAAL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059  96 TSITEKNENREKKRYLMGESMGGAVALLVHRKQPDYwDGAILVAPMCkiaedmrpnpltisfltklckiiptwkiiPTQD 175
Cdd:COG0412    98 DWLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPDL-AAAVSFYGGL-----------------------------PADD 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279778059 176 IIDIAFKVPeirkqirenrycykgrprlktghellrisselehkldevsVPFLLLHGEDDRVTDRLVSKQLYDE--AVSD 253
Cdd:COG0412   148 LLDLAARIK----------------------------------------APVLLLYGEKDPLVPPEQVAALEAAlaAAGV 187

                         250
                  ....*....|...
gi 1279778059 254 DKTLKMYPGMWHG 266
Cdd:COG0412   188 DVELHVYPGAGHG 200
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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