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Conserved domains on  [gi|1278648191|gb|PJB54619|]
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MAG: adenylate kinase [Bdellovibrio sp. CG_4_9_14_3_um_filter_39_7]

Protein Classification

adenylate kinase family protein( domain architecture ID 11426204)

adenylate kinase family protein such as adenylate kinase that catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0019205|GO:0005524|GO:0016310|GO:0006139
PubMed:  2841070|14568537|3023080

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 5-211 2.13e-89

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


:

Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 261.60  E-value: 2.13e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaY 81
Cdd:COG0563     3 IILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKerlAQPDCANG-F 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVVLKGSNS--KAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGsTELNQR 159
Cdd:COG0563    82 ILDGFPRTVAQAEALDELLAELGIKldAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCG-GELVQR 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1278648191 160 KDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:COG0563   161 ADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
 
Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 5-211 2.13e-89

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 261.60  E-value: 2.13e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaY 81
Cdd:COG0563     3 IILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKerlAQPDCANG-F 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVVLKGSNS--KAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGsTELNQR 159
Cdd:COG0563    82 ILDGFPRTVAQAEALDELLAELGIKldAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCG-GELVQR 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1278648191 160 KDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:COG0563   161 ADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 4-211 3.94e-82

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 242.91  E-value: 3.94e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK----KNTDLASG 79
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKerltQNDDNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  80 aYIFDGFPRNGDQAKLLDEvVLKGSNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPaQAGVCDKCGSTELNQR 159
Cdd:TIGR01351  81 -FILDGFPRTLSQAEALDA-LLEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPP-KVPGCDDCTGELLVQR 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1278648191 160 KDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEAL 209
adk PRK00279
adenylate kinase; Reviewed
 5-211 2.46e-78

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 233.50  E-value: 2.46e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaY 81
Cdd:PRK00279    3 LILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKerlAQPDCKNG-F 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEvVLKGSNSK---AVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGStELNQ 158
Cdd:PRK00279   82 LLDGFPRTIPQAEALDE-MLKELGIKldaVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGE-ELIQ 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1278648191 159 RKDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:PRK00279  160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKAL 212
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 4-203 6.65e-75

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 224.04  E-value: 6.65e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKK--NTDLASGAY 81
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKErlKKPDCKKGF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVVLKG-SNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLkfkapaqaGVCDKCGStELNQRK 160
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDEGiKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGE-PLSQRS 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1278648191 161 DDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEV 203
Cdd:cd01428   152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
7-188 1.27e-70

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 212.94  E-value: 1.27e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   7 FLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaYIF 83
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKerlEQNDCKNG-FLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  84 DGFPRNGDQAKLLDEVVLKGSNSKAV-YFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGsTELNQRKDD 162
Cdd:pfam00406  80 DGFPRTVPQAEALEELLERGIKLDYViEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTG-EPLVQRSDD 158

                         170       180
                  ....*....|....*....|....*.
gi 1278648191 163 VAETVKHRLDVFKETIEPVLKHYESE 188
Cdd:pfam00406 159 NEETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 5-211 2.13e-89

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 261.60  E-value: 2.13e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaY 81
Cdd:COG0563     3 IILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKerlAQPDCANG-F 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVVLKGSNS--KAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGsTELNQR 159
Cdd:COG0563    82 ILDGFPRTVAQAEALDELLAELGIKldAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCG-GELVQR 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1278648191 160 KDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:COG0563   161 ADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAIL 212
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 4-211 3.94e-82

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 242.91  E-value: 3.94e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK----KNTDLASG 79
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKerltQNDDNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  80 aYIFDGFPRNGDQAKLLDEvVLKGSNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPaQAGVCDKCGSTELNQR 159
Cdd:TIGR01351  81 -FILDGFPRTLSQAEALDA-LLEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPP-KVPGCDDCTGELLVQR 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1278648191 160 KDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEAL 209
adk PRK00279
adenylate kinase; Reviewed
 5-211 2.46e-78

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 233.50  E-value: 2.46e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaY 81
Cdd:PRK00279    3 LILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKerlAQPDCKNG-F 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEvVLKGSNSK---AVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGStELNQ 158
Cdd:PRK00279   82 LLDGFPRTIPQAEALDE-MLKELGIKldaVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGE-ELIQ 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1278648191 159 RKDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:PRK00279  160 RADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKAL 212
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 4-203 6.65e-75

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 224.04  E-value: 6.65e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKK--NTDLASGAY 81
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKErlKKPDCKKGF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVVLKG-SNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLkfkapaqaGVCDKCGStELNQRK 160
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDEGiKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGE-PLSQRS 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1278648191 161 DDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEV 203
Cdd:cd01428   152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
ADK pfam00406
Adenylate kinase;
7-188 1.27e-70

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 212.94  E-value: 1.27e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   7 FLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaYIF 83
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKerlEQNDCKNG-FLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  84 DGFPRNGDQAKLLDEVVLKGSNSKAV-YFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGsTELNQRKDD 162
Cdd:pfam00406  80 DGFPRTVPQAEALEELLERGIKLDYViEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTG-EPLVQRSDD 158

                         170       180
                  ....*....|....*....|....*.
gi 1278648191 163 VAETVKHRLDVFKETIEPVLKHYESE 188
Cdd:pfam00406 159 NEETVKKRLETYHKQTKPLIDYYKKK 184
PRK14530 PRK14530
adenylate kinase; Provisional
 1-211 1.30e-60

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 188.84  E-value: 1.30e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   1 MQPQLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLR-KEVKEASELGKRVT---AIMNAGKLVDDNTVLELLKKNTDL 76
Cdd:PRK14530    2 SQPRILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRaNKQMDISDMDTEYDtpgEYMDAGELVPDAVVNEIVEEALSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  77 ASGaYIFDGFPRNGDQAKLLDEVVlkgSNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGStEL 156
Cdd:PRK14530   82 ADG-FVLDGYPRNLEQAEYLESIT---DLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGG-EL 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1278648191 157 NQRKDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:PRK14530  157 IQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAI 211
PRK14526 PRK14526
adenylate kinase; Provisional
 4-211 2.60e-44

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 146.92  E-value: 2.60e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELL--KKNTDLASGAY 81
Cdd:PRK14526    2 KLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVedKINTIKNNDNF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVVlkgSNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGStELNQRKD 161
Cdd:PRK14526   82 ILDGFPRNINQAKALDKFL---PNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKG-DLYQRKD 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1278648191 162 DVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:PRK14526  158 DKEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEVKKKLIEII 207
PRK14531 PRK14531
adenylate kinase; Provisional
 1-202 1.54e-42

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 141.49  E-value: 1.54e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   1 MQPQLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKN-TDLASG 79
Cdd:PRK14531    1 MKQRLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQlKALNSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  80 AYIFDGFPRNGDQAKLLDEVV--LKGSNSKAVYFEIDLDLLFDRLVNRrtcgkcgeiynlkfkapaqagvcdkcgsteln 157
Cdd:PRK14531   81 GWLLDGFPRTVAQAEALEPLLeeLKQPIEAVVLLELDDAVLIERLLAR-------------------------------- 128

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1278648191 158 QRKDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDAsNGSDE 202
Cdd:PRK14531  129 GRADDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQSVEA-QGSIE 172
PLN02459 PLN02459
probable adenylate kinase
 4-202 8.24e-42

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 141.91  E-value: 8.24e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKNtdLASGA--- 80
Cdd:PLN02459   31 NWVFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKR--LEAGEeeg 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  81 ---YIFDGFPRNGDQAKLLDEVVlkgsnskavyfEIDL--------DLLFDRLVNRRTCGKCGEIYN-----LKFKAPAQ 144
Cdd:PLN02459  109 esgFILDGFPRTVRQAEILEGVT-----------DIDLvvnlklreEVLVEKCLGRRICSECGKNFNvadidLKGEDGRP 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278648191 145 AGVCD------KCGStELNQRKDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDE 202
Cdd:PLN02459  178 GIVMPpllpppECAS-KLITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEFELPGGIPE 240
PRK14527 PRK14527
adenylate kinase; Provisional
 5-204 2.53e-41

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 138.77  E-value: 2.53e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKN-TDLASGAYIF 83
Cdd:PRK14527    9 VIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDElAGMEPVRVIF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  84 DGFPRNGDQAKLLDEVV--LKGSNSKAVYFEIDLDLLFDRLVNRrtcgkcgeiynlkfkaPAQAGvcdkcgstelnqRKD 161
Cdd:PRK14527   89 DGFPRTLAQAEALDRLLeeLGARLLAVVLLEVPDEELIRRIVER----------------ARQEG------------RSD 140

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1278648191 162 DVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVF 204
Cdd:PRK14527  141 DNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGTPDEVY 183
PLN02674 PLN02674
adenylate kinase
 4-211 1.37e-38

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 133.09  E-value: 1.37e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVL----ELLKKNTdlASG 79
Cdd:PLN02674   33 RLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVgiidEAMKKPS--CQK 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  80 AYIFDGFPRNGDQAKLLDEVVLK-GSN-SKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVCDKCGSTeLN 157
Cdd:PLN02674  111 GFILDGFPRTVVQAQKLDEMLAKqGAKiDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEP-LI 189

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1278648191 158 QRKDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:PLN02674  190 QRKDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEVQKAL 243
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 5-211 3.17e-38

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 130.71  E-value: 3.17e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIF-LGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKNTDLASG---A 80
Cdd:TIGR01360   5 IIFiVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALGtskG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  81 YIFDGFPRNGDQAKLLDEVVlkGSNSKAVYFEIDLDLLFDRLVNRrtcgkcgeiynlkfkapaqagvcdkcgsTELNQRK 160
Cdd:TIGR01360  85 FLIDGYPREVKQGEEFERRI--GPPTLVLYFDCSEDTMVKRLLKR----------------------------AETSGRV 134

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1278648191 161 DDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:TIGR01360 135 DDNEKTIKKRLETYYKATEPVIAYYETKGKLRKINAEGTVDDVFLQVCTAI 185
PRK14532 PRK14532
adenylate kinase; Provisional
 5-209 9.70e-38

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 129.56  E-value: 9.70e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKNTDLASGA--YI 82
Cdd:PRK14532    3 LILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEAAggAI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  83 FDGFPRNGDQAKLLDEvVLKGSNSK---AVYFEIDLDLLFDRLVNRrtcgkcgeiynlkfkapaqagvcdkcgsTELNQR 159
Cdd:PRK14532   83 FDGFPRTVAQAEALDK-MLASRGQKidvVIRLKVDDEALIERIVKR----------------------------FEEQGR 133

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1278648191 160 KDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKS 209
Cdd:PRK14532  134 PDDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDGMGSIEAVAASIDA 183
PLN02842 PLN02842
nucleotide kinase
 9-211 2.03e-37

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 135.76  E-value: 2.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   9 GAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKN---TDLASGAYIFDG 85
Cdd:PLN02842    4 GAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRlsrEDAKEKGWLLDG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  86 FPRNGDQAKLLDEvvLKGSNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNLKFKAPAQAGVcdkcgSTELNQRKDDVAE 165
Cdd:PLN02842   84 YPRSFAQAQSLEK--LKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPESEEI-----KARLITRPDDTEE 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1278648191 166 TVKHRLDVFKETIEPVLKHYESegRLVRLDASNGSDEVFSSLKSLI 211
Cdd:PLN02842  157 KVKARLQIYKKNAEAILSTYSD--IMVKIDGNRPKEVVFEEISSLL 200
adk PRK02496
adenylate kinase; Provisional
 5-211 1.10e-36

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 126.40  E-value: 1.10e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGaY 81
Cdd:PRK02496    4 LIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQerlQQPDAANG-W 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVV--LKGSNSKAVYFEIDLDLLFDRLVNRrtcgkcgeiynlkfkapaqagvcdkcgstelnQR 159
Cdd:PRK02496   83 ILDGFPRKVTQAAFLDELLqeIGQSGERVVNLDVPDDVVVERLLAR--------------------------------GR 130

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1278648191 160 KDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSLI 211
Cdd:PRK02496  131 KDDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQSVEAVTTELKAAL 182
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 4-189 1.19e-35

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 125.30  E-value: 1.19e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLEL----LKKNTDLASG 79
Cdd:PTZ00088    8 KIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIvkdeIAKVTDDCFK 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  80 AYIFDGFPRNGDQAKlldEVVLKGSNSKAVYFEIDLDLLFDRLVNRRTCGKCGEIYNL------KFKAPA--QAGVCDKC 151
Cdd:PTZ00088   88 GFILDGFPRNLKQCK---ELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIahirsdPYDMPPilPPADCEGC 164

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1278648191 152 -GSTELNQRKDDVAETVKHRLDVFKETIEPVLKHYESEG 189
Cdd:PTZ00088  165 kGNPKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNEN 203
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 8-210 3.25e-32

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 115.16  E-value: 3.25e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   8 LGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVK-EASELGKRVTAIMNAGKLVDDNTVLELLKKNTDLASGAYIF--D 84
Cdd:TIGR01359   5 LGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKrEGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSSKKFliD 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  85 GFPRNGDQAKLLDEVVLKGSNSKAV-YFEIDLDLLFDRLVNRrtcgkcgeiynlkfkapaqagvcdkcgsTELNQRKDDV 163
Cdd:TIGR01359  85 GFPRNEENLEAWEKLMDNKVNFKFVlFFDCPEETMIKRLLKR----------------------------GQTSGRVDDN 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1278648191 164 AETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLKSL 210
Cdd:TIGR01359 137 IETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSVEEVFEDVEKI 183
PRK14528 PRK14528
adenylate kinase; Provisional
 4-207 3.57e-27

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 102.01  E-value: 3.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLK---KNTDLASGa 80
Cdd:PRK14528    3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKdriREADCKNG- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  81 YIFDGFPRNGDQAKLLDEVV--LKGSNSKAVYFEIDLDLLFDRLVNRrtcgkcgeiynlkfkapaqagvcdkcgsTELNQ 158
Cdd:PRK14528   82 FLLDGFPRTVEQADALDALLknEGKSIDKAINLEVPDGELLKRLLGR----------------------------AEIEG 133

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1278648191 159 RKDDVAETVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSL 207
Cdd:PRK14528  134 RADDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGSLEEVTSLI 182
PLN02200 PLN02200
adenylate kinase family protein
 8-208 1.24e-24

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 96.89  E-value: 1.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   8 LGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKNTDLA-SGAYIFDGF 86
Cdd:PLN02200   49 LGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSdNNKFLIDGF 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  87 PRNgDQAKLLDEVVLKGSNSKAVYFEIDLDLLFDRLVNRrtcgkcgeiynlkfkapaqagvcdkcgstelNQ-RKDDVAE 165
Cdd:PLN02200  129 PRT-EENRIAFERIIGAEPNVVLFFDCPEEEMVKRVLNR-------------------------------NQgRVDDNID 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1278648191 166 TVKHRLDVFKETIEPVLKHYESEGRLVRLDASNGSDEVFSSLK 208
Cdd:PLN02200  177 TIKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTVDEIFEQVR 219
PRK13808 PRK13808
adenylate kinase; Provisional
 4-203 7.47e-24

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 96.50  E-value: 7.47e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   4 QLIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLVDDNTVLELLKKNTDL--ASGAY 81
Cdd:PRK13808    2 RLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQpdAANGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  82 IFDGFPRNGDQAKLLDEVVL-KGSNSKAVY-FEIDLDLLFDRLVNR----RTCGKcgeiynlkfkapaqagvcdkcgste 155
Cdd:PRK13808   82 ILDGFPRTVPQAEALDALLKdKQLKLDAVVeLRVNEGALLARVETRvaemRARGE------------------------- 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1278648191 156 lNQRKDDVAETVKHRLDVFKETIEPvLKHYESEGR-LVRLDASNGSDEV 203
Cdd:PRK13808  137 -EVRADDTPEVLAKRLASYRAQTEP-LVHYYSEKRkLLTVDGMMTIDEV 183
AAA_17 pfam13207
AAA domain;
8-127 1.16e-23

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 91.53  E-value: 1.16e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   8 LGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEaSELGKRVTAIMNAGKLVDDNTVLELLKK-NTDLASGAYIFDGF 86
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKE-RGLVEDRDEMRKLPLEPQKELQKLAAERiAEEAGEGGVIVDGH 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1278648191  87 PRNGDQA----KLLDEVVLKGSNSKAVYFEIDLDLLFDRLVNRRT 127
Cdd:pfam13207  80 PRIKTPAgylpGLPVEVLRELKPDAIILLEADPEEILERRLKDRT 124
PRK14529 PRK14529
adenylate kinase; Provisional
 5-207 5.28e-17

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 76.30  E-value: 5.28e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGTQATRLIKECGYQHLSTGDLLRKEVKEASELGKRVTAIMNAGKLV-DDNT---VLELLKKntDLASGa 80
Cdd:PRK14529    3 ILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVpDDITipmILETLKQ--DGKNG- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191  81 YIFDGFPRNGDQAKLLDEVVLKGSNSKAVYFEIDLD--LLFDRLVNRRTC-GKCGEIYNLKFKAPAQAG-VCDKCGStEL 156
Cdd:PRK14529   80 WLLDGFPRNKVQAEKLWEALQKEGMKLDYVIEILLPreVAKNRIMGRRLCkNDNNHPNNIFIDAIKPDGdVCRVCGG-EL 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191 157 NQRKDDVAET-VKHRLDVFKETIEPVL------KHYESEGRL--VRLDASNGSDEVFSSL 207
Cdd:PRK14529  159 STRADDQDEEaINKRHDIYYDTETGTLaaayffKDLAAKGSTkyIELDGEGSIDEIKETL 218
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 125-161 4.09e-14

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 63.63  E-value: 4.09e-14
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1278648191 125 RRTCGKCGEIYNLKFKAPAQAGVCDKCGStELNQRKD 161
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGG-ELVQRDD 36
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 5-125 3.53e-09

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 53.47  E-value: 3.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFL-GAPGSGKGTQATRLIKECGYQHLSTgDLLRKEVKEasELGKRVTAIMNAGKLVdDNTVLELLKKNtdLASGA-YI 82
Cdd:pfam13671   1 LILLvGLPGSGKSTLARRLLEELGAVRLSS-DDERKRLFG--EGRPSISYYTDATDRT-YERLHELARIA--LRAGRpVI 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1278648191  83 FD-GFPRNGDQAKLLDEVVLKGSNSKAVYFEIDLDLLFDRLVNR 125
Cdd:pfam13671  75 LDaTNLRRDERARLLALAREYGVPVRIVVFEAPEEVLRERLAAR 118
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
5-44 8.33e-05

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 41.86  E-value: 8.33e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFLGAPGSGKGtQATRLIKECGYQHLSTGDLLRKEVKEA 44
Cdd:PRK01184    4 IGVVGMPGSGKG-EFSKIAREMGIPVVVMGDVIREEVKKR 42
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 9-47 6.11e-04

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 38.62  E-value: 6.11e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1278648191   9 GAPGSGKGTQATRLIKECGYQHLSTGDLLRKEV-KEASEL 47
Cdd:cd02020     6 GPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEEVgKLASEV 45
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
5-126 1.70e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 37.59  E-value: 1.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278648191   5 LIFL-GAPGSGKGTQATRLIKECGYQHLSTgDLLRKEVKEA--------SELGKRVTAIMNAgklvddnTVLELLKKNTD 75
Cdd:COG0645     1 LILVcGLPGSGKSTLARALAERLGAVRLRS-DVVRKRLFGAglaplersPEATARTYARLLA-------LARELLAAGRS 72

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1278648191  76 LasgayIFD-GFPRNGDQAKLLDEVVLKGSNSKAVYFEIDLDLLFDRLVNRR 126
Cdd:COG0645    73 V-----ILDaTFLRRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEARN 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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