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Conserved domains on  [gi|1278569316|gb|PJA83861|]
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hypothetical protein CO147_00200 [Nitrospirae bacterium CG_4_9_14_3_um_filter_44_28]

Protein Classification

type II toxin-antitoxin system HicB family antitoxin( domain architecture ID 10003996)

type II toxin-antitoxin system HicB family antitoxin is the antitoxin component of a type II toxin-antitoxin (TA) system and functions as an mRNA interferase antitoxin preventing effects of the cognate HicA family toxin

Gene Ontology:  GO:0110001
PubMed:  17329807|16895922|28279904|30337369
SCOP:  4001747

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HicB COG1598
Antitoxin component HicB of the HicAB toxin-antitoxin system [Defense mechanisms];
14-73 4.11e-09

Antitoxin component HicB of the HicAB toxin-antitoxin system [Defense mechanisms];


:

Pssm-ID: 441206  Cd Length: 65  Bit Score: 47.57  E-value: 4.11e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278569316 14 HYEII---EDEGAFWGEISGLQGVWGKAKTLEECRSALKEALEEWIIFRLKNNLELPVIAGID 73
Cdd:COG1598    1 KYPAIiekDEDGGYVAEVPDLPGCVTQGDTLEEALENAKEALELHLEALLEDGEPIPEPSSIE 63
 
Name Accession Description Interval E-value
HicB COG1598
Antitoxin component HicB of the HicAB toxin-antitoxin system [Defense mechanisms];
14-73 4.11e-09

Antitoxin component HicB of the HicAB toxin-antitoxin system [Defense mechanisms];


Pssm-ID: 441206  Cd Length: 65  Bit Score: 47.57  E-value: 4.11e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278569316 14 HYEII---EDEGAFWGEISGLQGVWGKAKTLEECRSALKEALEEWIIFRLKNNLELPVIAGID 73
Cdd:COG1598    1 KYPAIiekDEDGGYVAEVPDLPGCVTQGDTLEEALENAKEALELHLEALLEDGEPIPEPSSIE 63
 
Name Accession Description Interval E-value
HicB COG1598
Antitoxin component HicB of the HicAB toxin-antitoxin system [Defense mechanisms];
14-73 4.11e-09

Antitoxin component HicB of the HicAB toxin-antitoxin system [Defense mechanisms];


Pssm-ID: 441206  Cd Length: 65  Bit Score: 47.57  E-value: 4.11e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278569316 14 HYEII---EDEGAFWGEISGLQGVWGKAKTLEECRSALKEALEEWIIFRLKNNLELPVIAGID 73
Cdd:COG1598    1 KYPAIiekDEDGGYVAEVPDLPGCVTQGDTLEEALENAKEALELHLEALLEDGEPIPEPSSIE 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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