|
Name |
Accession |
Description |
Interval |
E-value |
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
1-422 |
0e+00 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 719.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 1 MNTPLAERIRPLVLEDFISQQHLVGKTGVLTQSIAHGVIPSLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAINSGVKDV 80
Cdd:COG2256 11 ANAPLAERMRPRTLDEVVGQEHLLGPGKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANATDAEFVALSAVTSGVKDI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 81 RDVIDKAKQSggLFTTKNPILFIDEIHRFSKSQQDSLLGAVEKGWITLIGATTENPSFEVIPALLSRCQVYILNAFDKAD 160
Cdd:COG2256 91 REVIEEARER--RAYGRRTILFVDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNSALLSRCRVFVLKPLSEED 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 161 LKALLNRALKVD-VELKQKQINLKE--TEALIHLSGGDARKLLNIFELVI---GQNTKIDITNELVLKAIQQNPARYDKT 234
Cdd:COG2256 169 LEQLLERALADDeRGLGGYKLELDDeaLEALARLADGDARRALNALELAVlsaPPDGVIEITLELVEEALQRRALRYDKD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 235 GEQHYDIISAFIKSIRGSDPNAAVYWLARMIEGGEDVKFIARRMLILASEDIGNANPTALIIANNTFQAVSIIGNPESRI 314
Cdd:COG2256 249 GDEHYDLISAFIKSIRGSDPDAALYWLARMLEAGEDPRFIARRLVIMASEDIGLADPQALQIAVAAAQAVERLGMPEGRI 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 315 ILSQCATYLASSPKSNASYTAISKAQELVQKTGDLSVPLHLRNAPTKLMKDLNYGKDYQYAHNFESNFVNQEFLPDQITN 394
Cdd:COG2256 329 ALAQAVIYLATAPKSNAAYLAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPGGYVGQQYLPDELKG 408
|
410 420
....*....|....*....|....*...
gi 1278483409 395 TQLYEPGNNARENQLRLYLKTLWKDKYG 422
Cdd:COG2256 409 RRYYEPTERGFERKIKERLEKLRKLRRG 436
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
4-420 |
0e+00 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 685.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 4 PLAERIRPLVLEDFISQQHLVGKTGVLTQSIAHGVIPSLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAINSGVKDVRDV 83
Cdd:PRK13342 1 PLAERMRPKTLDEVVGQEHLLGPGKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGATDAPFEALSAVTSGVKDLREV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 84 IDKAKQSggLFTTKNPILFIDEIHRFSKSQQDSLLGAVEKGWITLIGATTENPSFEVIPALLSRCQVYILNAFDKADLKA 163
Cdd:PRK13342 81 IEEARQR--RSAGRRTILFIDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNPALLSRAQVFELKPLSEEDIEQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 164 LLNRALKvDVELKQKQINLKETEALIHLSGGDARKLLNIFELVIgqNTKIDITNELVLKAIQQNPARYDKTGEQHYDIIS 243
Cdd:PRK13342 159 LLKRALE-DKERGLVELDDEALDALARLANGDARRALNLLELAA--LGVDSITLELLEEALQKRAARYDKDGDEHYDLIS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 244 AFIKSIRGSDPNAAVYWLARMIEGGEDVKFIARRMLILASEDIGNANPTALIIANNTFQAVSIIGNPESRIILSQCATYL 323
Cdd:PRK13342 236 ALHKSIRGSDPDAALYYLARMLEAGEDPLFIARRLVIIASEDIGLADPNALQVAVAAADAVERIGMPEGRIALAQAVIYL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 324 ASSPKSNASYTAISKAQELVQKTGDLSVPLHLRNAPTKLMKDLNYGKDYQYAHNFESNFVNQEFLPDQITNTQLYEPGNN 403
Cdd:PRK13342 316 ALAPKSNAAYTAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPNGYVGQQYLPDELKGKRYYEPTER 395
|
410
....*....|....*..
gi 1278483409 404 ARENQLRLYLKTLWKDK 420
Cdd:PRK13342 396 GFEKKIKERLEKLKDKN 412
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
4-422 |
1.98e-163 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 476.85 E-value: 1.98e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 4 PLAERIRPLVLEDFISQQHLVGKTGVLTQSIAHGVIPSLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAINSGVKDVRDV 83
Cdd:PRK13341 17 PLADRLRPRTLEEFVGQDHILGEGRLLRRAIKADRVGSLILYGPPGVGKTTLARIIANHTRAHFSSLNAVLAGVKDLRAE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 84 IDKAKQSGGLFTtKNPILFIDEIHRFSKSQQDSLLGAVEKGWITLIGATTENPSFEVIPALLSRCQVYILNAFDKADLKA 163
Cdd:PRK13341 97 VDRAKERLERHG-KRTILFIDEVHRFNKAQQDALLPWVENGTITLIGATTENPYFEVNKALVSRSRLFRLKSLSDEDLHQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 164 LLNRALKvDVE--LKQKQINLkETEALIHL---SGGDARKLLNIFELVI-----GQNTKIDITNELVLKAIQQNPARYDK 233
Cdd:PRK13341 176 LLKRALQ-DKErgYGDRKVDL-EPEAEKHLvdvANGDARSLLNALELAVestppDEDGLIDITLAIAEESIQQRAVLYDK 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 234 TGEQHYDIISAFIKSIRGSDPNAAVYWLARMIEGGEDVKFIARRMLILASEDIGNANPTALIIANNTFQAVSIIGNPESR 313
Cdd:PRK13341 254 EGDAHFDTISAFIKSLRGSDPDAALYWLARMVEAGEDPRFIFRRMLIAASEDVGLADPQALVVVEACAAAFERVGLPEGL 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 314 IILSQCATYLASSPKSNaSYTAISKAQELVQKTGDLSVPLHLRNaPTKLMKDLNYGKDYQYAHNFESNFVNQEFLPDQIT 393
Cdd:PRK13341 334 YPLAQAALYLATAPKSN-SVLGFFDALKKVREEQVQDVPNHLRD-ANRDGKAFGDGVGYRYPHAFRDHWVAQQYLPEALQ 411
|
410 420
....*....|....*....|....*....
gi 1278483409 394 NTQLYEPGNNARENQLRLYLKTLWKDKYG 422
Cdd:PRK13341 412 GEVFWQPSRQGWEGERRERLARRRAAQLA 440
|
|
| MgsA_C |
pfam12002 |
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA ... |
251-406 |
3.49e-102 |
|
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication. Additionally, MgsA may play a role in chromosomal segregation. This is consistent with a report that MgsA co-localizes with the replisome and affects chromosome segregation. This domain represents the C terminal region of MgsA.
Pssm-ID: 463426 [Multi-domain] Cd Length: 158 Bit Score: 300.03 E-value: 3.49e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 251 GSDPNAAVYWLARMIEGGEDVKFIARRMLILASEDIGNANPTALIIANNTFQAVSIIGNPESRIILSQCATYLASSPKSN 330
Cdd:pfam12002 1 GSDPDAALYWLARMLEAGEDPLFIARRLVIIASEDIGLADPQALVVAVAAAQAVERIGMPEARIPLAQAVIYLALAPKSN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278483409 331 ASYTAISKAQELVQKTGDLSVPLHLRNAPTKLMKDLNYGKDYQYAHNFESNFVNQEFLPDQITNTQLYEPGNNARE 406
Cdd:pfam12002 81 SAYLAIDAALADVREGGSLPVPLHLRNAPTKLMKKLGYGKGYKYPHDYPNGYVKQQYLPDELKGRRYYEPTDNGYE 156
|
|
| PRK14700 |
PRK14700 |
recombination factor protein RarA; Provisional |
121-420 |
4.32e-68 |
|
recombination factor protein RarA; Provisional
Pssm-ID: 173163 [Multi-domain] Cd Length: 300 Bit Score: 218.34 E-value: 4.32e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 121 VEKGWITLIGATTENPSFEVIPALLSRCQVYILNAFDKADLKALLNRALKVDVELKQKQINLKET--EALIHLSGGDARK 198
Cdd:PRK14700 4 VESGKIILIGATTENPTYYLNDALVSRLFILRLKRLSLVATQKLIEKALSQDEVLAKHKFKIDDGlyNAMHNYNEGDCRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 199 LLNIFE---LVIGQNTKIDITNELVLKAIQQNPARYDKTGEQHYDIISAFIKSIRGSDPNAAVYWLARMIEGGEDVKFIA 275
Cdd:PRK14700 84 ILNLLErmfLISTRGDEIYLNKELFDQAVGETSRDFHREGKEFYEQLSAFHKSVRGTDPDAAIFWLSVMLDNGVDPLVIA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 276 RRMLILASEDIGNANPTALIIANNTFQAVSIIGNPESRIILSQCATYLASSPKSNASYTAISKAQELVQKTGDLSVPLHL 355
Cdd:PRK14700 164 RRMLCIASEDIGNADPQALRVAMDAWNAYEKLGMPEGRLVLAQAAIYLAVAPKSNACYKALAQAQQLVKSLGNIDVPQHL 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1278483409 356 RNaptklMKDLNygkdYQYAHNFESNFVNQEFLPDQITNTqLYEPGNNARENQLRLYLKTLWKDK 420
Cdd:PRK14700 244 KN-----YKDSN----YLYPHNYPNSYVIQQYLPDNIIQN-FYQPTASGFEAKIKTKLDSINKIK 298
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
176-250 |
4.38e-28 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 106.01 E-value: 4.38e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 176 KQKQINLKET--EALIHLSGGDARKLLNIFELVI----GQNTKIDITNELVLKAIQQNPARYDKTGEQHYDIISAFIKSI 249
Cdd:pfam16193 1 GGLKIELDDEalEALAELADGDARRALNALELAVlstpPDDGGIHITLEILEEALQRKALRYDKDGDEHYDLISAFHKSI 80
|
.
gi 1278483409 250 R 250
Cdd:pfam16193 81 R 81
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
42-153 |
1.29e-20 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 86.88 E-value: 1.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSGGlfttknPILFIDEIHRFSKSQQ 114
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGselvskyVGESEKRLRELFEAAKKLAP------CVIFIDEIDALAGSRG 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1278483409 115 DSLLGAVEK----------------GWITLIGATTEnpSFEVIPALLSRCQVYIL 153
Cdd:pfam00004 75 SGGDSESRRvvnqllteldgftssnSKVIVIAATNR--PDKLDPALLGRFDRIIE 127
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
9-133 |
7.08e-18 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 84.03 E-value: 7.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 9 IRPLVLEDFISQQHLVGKTGVLTQS-------IAHgvipsLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAinsgvkdvr 81
Cdd:PRK00080 19 LRPKSLDEFIGQEKVKENLKIFIEAakkrgeaLDH-----VLLYGPPGLGKTTLANIIANEMGVNIRITSG--------- 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278483409 82 DVIDKAKQSGGLFTT--KNPILFIDEIHRFSKSQQDSLLGAVEKGWI--------------------TLIGATT 133
Cdd:PRK00080 85 PALEKPGDLAAILTNleEGDVLFIDEIHRLSPVVEEILYPAMEDFRLdimigkgpaarsirldlppfTLIGATT 158
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
9-133 |
1.43e-17 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 79.47 E-value: 1.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 9 IRPLVLEDFISQQHLVGKTGVLTQ-------SIAHgvipsLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAinsgvkdvr 81
Cdd:pfam05496 1 LRPRTLDEYIGQEKVKENLKIFIEaakqrgeALDH-----VLLYGPPGLGKTTLANIIANEMGVNIRITSG--------- 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278483409 82 DVIDKAKQSGGLFTTKNP--ILFIDEIHRFSKSQQDSLLGAVEKGWI--------------------TLIGATT 133
Cdd:pfam05496 67 PAIERPGDLAAILTNLEPgdVLFIDEIHRLNRAVEEILYPAMEDFRLdivigkgpsarsirldlppfTLVGATT 140
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
30-152 |
5.49e-17 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 77.57 E-value: 5.49e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 30 LTQSIAHGVIPSLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAINSGVKDVRDVIDKAKQSGGLFT-------TKNPILF 102
Cdd:cd00009 10 LREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLlfelaekAKPGVLF 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1278483409 103 IDEIHRFSKSQQDSLLGAVEKGW--------ITLIGATTENPSFEVIPALLSRCQVYI 152
Cdd:cd00009 90 IDEIDSLSRGAQNALLRVLETLNdlridrenVRVIGATNRPLLGDLDRALYDRLDIRI 147
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
9-133 |
5.29e-16 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 78.58 E-value: 5.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 9 IRPLVLEDFISQQHLVGKTGVLTQ-------SIAHgvipsLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAinsgvkdvr 81
Cdd:COG2255 22 LRPKRLDEYIGQEKVKENLKIFIEaakkrgeALDH-----VLLYGPPGLGKTTLAHIIANEMGVNIRITSG--------- 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278483409 82 DVIDKAKQSGGLFTTKNP--ILFIDEIHRFSKSQQDSLLGAVE---------KGW-----------ITLIGATT 133
Cdd:COG2255 88 PAIEKPGDLAAILTNLEEgdVLFIDEIHRLSRVVEEILYPAMEdfrldivigKGPaarsirldlppFTLVGATT 161
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
6-207 |
5.75e-16 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 79.82 E-value: 5.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 6 AERIRPLVLEDFISQQHLVG--KTGVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIANT-----------------SKRP 66
Cdd:PRK14971 8 ARKYRPSTFESVVGQEALTTtlKNAIATNKLAH----AYLFCGPRGVGKTTCARIFAKTincqnltadgeacneceSCVA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 67 F--------YSL-SAINSGVKDVRDVIDKAK---QSGglfttKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGAT 132
Cdd:PRK14971 84 FneqrsyniHELdAASNNSVDDIRNLIEQVRippQIG-----KYKIYIIDEVHMLSQAAFNAFLKTLEEppSYAIFILAT 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1278483409 133 TENpsFEVIPALLSRCQVYILNAFDKADLKALLNralkvDVElKQKQINlKETEALiHLSG----GDARKLLNIFELVI 207
Cdd:PRK14971 159 TEK--HKILPTILSRCQIFDFNRIQVADIVNHLQ-----YVA-SKEGIT-AEPEAL-NVIAqkadGGMRDALSIFDQVV 227
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
6-207 |
7.18e-16 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 78.38 E-value: 7.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 6 AERIRPLVLEDFISQQHLvgkTGVLTQSIAHGVIPS-LIFWGPPGIGKTTLAAIIANTSKRPFYSLS------------- 71
Cdd:PRK14970 8 ARKYRPQTFDDVVGQSHI---TNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPGYDDPnedfsfnifelda 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 72 AINSGVKDVRDVIDKAK---QSGglfttKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTENpsFEVIPALLS 146
Cdd:PRK14970 85 ASNNSVDDIRNLIDQVRippQTG-----KYKIYIIDEVHMLSSAAFNAFLKTLEEppAHAIFILATTEK--HKIIPTILS 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1278483409 147 RCQVYILNAFDKADLKALLnralkvdVELKQKQINLKETEALiHL----SGGDARKLLNIFELVI 207
Cdd:PRK14970 158 RCQIFDFKRITIKDIKEHL-------AGIAVKEGIKFEDDAL-HIiaqkADGALRDALSIFDRVV 214
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
11-298 |
1.11e-15 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 77.54 E-value: 1.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 11 PLVLEDFISQQHLVgKTgvLTQSIAHGVIP-SLIFWGPPGIGKTTLAAIIA---NTSKRP-------------FYSLSAI 73
Cdd:COG2812 6 PQTFDDVVGQEHVV-RT--LKNALASGRLAhAYLFTGPRGVGKTTLARILAkalNCENGPtgepcgecescraIAAGSHP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 74 ----------NSGVKDVRDVIDKAKQSGglFTTKNPILFIDEIHRFSKSQQDSLLgaveKgwiTL---------IGATTE 134
Cdd:COG2812 83 dvieidaeasNIGVDDIRELIEKVSYAP--VEGRYKVYIIDEAHMLTTEAFNALL----K---TLeeppphvvfILATTE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 135 nPSfEVIPALLSRCQVYILNAFDKADLKALLNRalkvdvELKQKQINLKETEA--LIHLSGGDARKLLNIFELVIGQNTK 212
Cdd:COG2812 154 -PQ-KLLPTILSRCQRFDFRRLPPEEIAEHLAK------IAEREGIEIEPEALalIARAADGSMRDALSLLDQAIAFGLL 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 213 iditnelvlkaiqqnparydktgeQHYDIISAFIKSIRGSDPNAAVYWLARMIEGGEDVKFIA-------RRMLILased 285
Cdd:COG2812 226 ------------------------DRRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLddllsllRDLLLL---- 277
|
330
....*....|...
gi 1278483409 286 igNANPTALIIAN 298
Cdd:COG2812 278 --KLGPDAELLVN 288
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
35-238 |
3.16e-15 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 74.92 E-value: 3.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 35 AHGVIPS--LIFWGPPGIGKTTLAAIIANTSKRPFYSL---SAINS----GVKDVRDVIDKAKQSGGlfttknpILFIDE 105
Cdd:COG1223 29 KFGLWPPrkILFYGPPGTGKTMLAEALAGELKLPLLTVrldSLIGSylgeTARNLRKLFDFARRAPC-------VIFFDE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 106 IHRFSKS---QQD---------SLLGAVE--KGWITLIGATTeNPsfEVI-PALLSRCQVYI-LNAFDKADLKALLN--- 166
Cdd:COG1223 102 FDAIAKDrgdQNDvgevkrvvnALLQELDglPSGSVVIAATN-HP--ELLdSALWRRFDEVIeFPLPDKEERKEILElnl 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278483409 167 RALKVDVELKQKQInLKETEAlihLSGGDARKLLN--IFELVIGQNTKidITNELVLKAIQQNPARYDKTGEQH 238
Cdd:COG1223 179 KKFPLPFELDLKKL-AKKLEG---LSGADIEKVLKtaLKKAILEDREK--VTKEDLEEALKQRKERKKEPKKEG 246
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
10-216 |
1.03e-14 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 76.04 E-value: 1.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 10 RPLVLEDFISQQHLvgkTGVLTQSIAHGVIP-SLIFWGPPGIGKTTLAAIIA------------------------NTSK 64
Cdd:PRK05896 11 RPHNFKQIIGQELI---KKILVNAILNNKLThAYIFSGPRGIGKTSIAKIFAkainclnpkdgdccnscsvcesinTNQS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 65 RPFYSL-SAINSGVKDVRDVIDKAKQSGGLFTTKnpILFIDEIHRFSKSQQDSLLGAVEKG--WITLIGATTEnpsFEVI 141
Cdd:PRK05896 88 VDIVELdAASNNGVDEIRNIIDNINYLPTTFKYK--VYIIDEAHMLSTSAWNALLKTLEEPpkHVVFIFATTE---FQKI 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278483409 142 P-ALLSRCQVYILNAFDKADLKALLNRALKvdvelKQK-QINLKETEALIHLSGGDARKLLNIF-ELVIGQNTKIDIT 216
Cdd:PRK05896 163 PlTIISRCQRYNFKKLNNSELQELLKSIAK-----KEKiKIEDNAIDKIADLADGSLRDGLSILdQLSTFKNSEIDIE 235
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
35-226 |
5.19e-14 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 73.02 E-value: 5.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 35 AHGVIPS--LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA---INSGV----KDVRDVIDKAKQSgglfttKNPILFIDE 105
Cdd:COG0464 185 EYGLPPPrgLLLYGPPGTGKTLLARALAGELGLPLIEVDLsdlVSKYVgeteKNLREVFDKARGL------APCVLFIDE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 106 I-----------HRFSKSQQDSLL---GAVEKGWItLIGATteNpSFEVI-PALLSRCQVYIlnAF---DKADLKALLNR 167
Cdd:COG0464 259 AdalagkrgevgDGVGRRVVNTLLtemEELRSDVV-VIAAT--N-RPDLLdPALLRRFDEII--FFplpDAEERLEIFRI 332
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278483409 168 ALKvDVELKqKQINLKE-TEALIHLSGGDARkllNIFELVIGQNTKID---ITNELVLKAIQQ 226
Cdd:COG0464 333 HLR-KRPLD-EDVDLEElAEATEGLSGADIR---NVVRRAALQALRLGrepVTTEDLLEALER 390
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
30-289 |
7.31e-14 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 71.54 E-value: 7.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 30 LTQSIAHGVIP-SLIFWGPPGIGKTTLAAIIAN----TSKRP-------------------FYSLSAINS----GVKDVR 81
Cdd:COG0470 8 LLAAAESGRLPhALLLHGPPGIGKTTLALALARdllcENPEGgkacgqchsrlmaagnhpdLLELNPEEKsdqiGIDQIR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 82 DVIDKAKQSGglFTTKNPILFIDEIHRFSKSQQDSLLGAVE----KGWITLIgatTENPSfEVIPALLSRCQVYILNAFD 157
Cdd:COG0470 88 ELGEFLSLTP--LEGGRKVVIIDEADAMNEAAANALLKTLEeppkNTPFILI---ANDPS-RLLPTIRSRCQVIRFRPPS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 158 KADLKALlnralkvdveLKQKQINLKETEALIHLSGGDARKLLNIFELVIGQNTkiditnelVLKAIQQNPARYDKtgeq 237
Cdd:COG0470 162 EEEALAW----------LREEGVDEDALEAILRLAGGDPRAAINLLQALAGRKE--------LLEDLAALLSRDRA---- 219
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1278483409 238 hYDIISAFIKsirgSDPNAAVYWLARMIEggEDVKF-IARRMLILASEDIGNA 289
Cdd:COG0470 220 -LELLDALLK----AEALELLDWLLKWLL--DNLPLeYAGEDLARAYEALSEA 265
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
13-251 |
8.95e-14 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 71.56 E-value: 8.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 13 VLEDFISQQHLVGKTGVLTQS--IAHGVIPSLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAinsgvkdvrDVIDKAKQS 90
Cdd:TIGR00635 2 LLAEFIGQEKVKEQLQLFIEAakMRQEALDHLLLYGPPGLGKTTLAHIIANEMGVNLKITSG---------PALEKPGDL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 91 GGLFTTKNP--ILFIDEIHRFSKSQQDSLLGAVE---------KGW-----------ITLIGATTEnpSFEVIPALLSRC 148
Cdd:TIGR00635 73 AAILTNLEEgdVLFIDEIHRLSPAVEELLYPAMEdfrldivigKGPsarsvrldlppFTLVGATTR--AGMLTSPLRDRF 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 149 QVYI-LNAFDKADLKALLNR-ALKVDVELKQKQInlketEALIHLSGGDARKLLNI------FELVIGQNtkiDITNELV 220
Cdd:TIGR00635 151 GIILrLEFYTVEELAEIVSRsAGLLNVEIEPEAA-----LEIARRSRGTPRIANRLlrrvrdFAQVRGQK---IINRDIA 222
|
250 260 270
....*....|....*....|....*....|...
gi 1278483409 221 LKAIqqNPARYDKTGEQHYD--IISAFIKSIRG 251
Cdd:TIGR00635 223 LKAL--EMLMIDELGLDEIDrkLLSVLIEQFQG 253
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
5-204 |
2.10e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 71.76 E-value: 2.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLVGktgVLTQSIAHG-VIPSLIFWGPPGIGKTTLAAIIANT--------SKRPFYSLS---- 71
Cdd:PRK14950 6 LYRKWRSQTFAELVGQEHVVQ---TLRNAIAEGrVAHAYLFTGPRGVGKTSTARILAKAvncttndpKGRPCGTCEmcra 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 72 --------------AINSGVKDVRDVIDKAKQSGGLFTTKnpILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTEn 135
Cdd:PRK14950 83 iaegsavdviemdaASHTSVDDAREIIERVQFRPALARYK--VYIIDEVHMLSTAAFNALLKTLEEppPHAIFILATTE- 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1278483409 136 pSFEVIPALLSRCQVYILNAFDKADLKALLNRAlkvdveLKQKQINLKE--TEALIHLSGGDARKLLNIFE 204
Cdd:PRK14950 160 -VHKVPATILSRCQRFDFHRHSVADMAAHLRKI------AAAEGINLEPgaLEAIARAATGSMRDAENLLQ 223
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
1-224 |
3.35e-12 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 66.82 E-value: 3.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 1 MNTPLAERIRPLVLEDFISQQHLVGKtgvLTQSIAHGVIPSLIFWGPPGIGKTTLAAIIA-----NTSKRPFYSLSAINS 75
Cdd:PRK00440 3 MEEIWVEKYRPRTLDEIVGQEEIVER---LKSYVKEKNMPHLLFAGPPGTGKTTAALALArelygEDWRENFLELNASDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 76 -GVKDVRDVID---KAKQSGGL-FTtknpILFIDEIHRFSKSQQDSLLGAVEKgwitligaTTENPSF--------EVIP 142
Cdd:PRK00440 80 rGIDVIRNKIKefaRTAPVGGApFK----IIFLDEADNLTSDAQQALRRTMEM--------YSQNTRFilscnyssKIID 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 143 ALLSRCQVYILNAFDKADLKALLNR-ALKVDVELKQKQInlketEALIHLSGGDARKLLNIfeLVIGQNTKIDITNELVL 221
Cdd:PRK00440 148 PIQSRCAVFRFSPLKKEAVAERLRYiAENEGIEITDDAL-----EAIYYVSEGDMRKAINA--LQAAAATGKEVTEEAVY 220
|
...
gi 1278483409 222 KAI 224
Cdd:PRK00440 221 KIT 223
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
5-147 |
4.46e-12 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 63.84 E-value: 4.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLVGKTGVLtqsiahgvipsliFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGV 77
Cdd:cd19481 5 LREAVEAPRRGSRLRRYGLGLPKGIL-------------LYGPPGTGKTLLAKALAGELGLPLIVVKLssllskyVGESE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 78 KDVRDVIDKAKQSGGlfttknPILFIDEIHRFSKSQQDS------------LL----GAVEKGWITLIGATteNPSFEVI 141
Cdd:cd19481 72 KNLRKIFERARRLAP------CILFIDEIDAIGRKRDSSgesgelrrvlnqLLteldGVNSRSKVLVIAAT--NRPDLLD 143
|
....*.
gi 1278483409 142 PALLSR 147
Cdd:cd19481 144 PALLRP 149
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
5-274 |
8.11e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 66.89 E-value: 8.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLVG--KTGVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIAN--TSKRP-------------- 66
Cdd:PRK14956 8 LSRKYRPQFFRDVIHQDLAIGalQNALKSGKIGH----AYIFFGPRGVGKTTIARILAKrlNCENPignepcnectscle 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 67 ---------FYSLSAINSGVKDVRDVIDKAKQS--GGlfttKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATT 133
Cdd:PRK14956 84 itkgissdvLEIDAASNRGIENIRELRDNVKFApmGG----KYKVYIIDEVHMLTDQSFNALLKTLEEppAHIVFILATT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 134 EnpsFEVIP-ALLSRCQVYIlnaFDKADLKALLNRALKVdvelkQKQINLK-ETEALIHLS---GGDARKLLNIFELVIg 208
Cdd:PRK14956 160 E---FHKIPeTILSRCQDFI---FKKVPLSVLQDYSEKL-----CKIENVQyDQEGLFWIAkkgDGSVRDMLSFMEQAI- 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1278483409 209 QNTKIDITNELVLKAIqqnparydktGEQHYDIISAFIKSIRGSDPNAAVY-WLARMIEGGEDV-KFI 274
Cdd:PRK14956 228 VFTDSKLTGVKIRKMI----------GYHGIEFLTSFIKSLIDPDNHSKSLeILESLYQEGQDIyKFL 285
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
37-106 |
2.26e-11 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 62.04 E-value: 2.26e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1278483409 37 GVIPS--LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA--INSGV-----KDVRDVIDKAKQsgglftTKNPILFIDEI 106
Cdd:cd19518 30 GVEPPrgVLLHGPPGCGKTMLANAIAGELKVPFLKISAteIVSGVsgeseEKIRELFDQAIS------NAPCIVFIDEI 102
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
5-182 |
2.26e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 65.25 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLvgkTGVLTQSIAHG-VIPSLIFWGPPGIGKTTLAAIIANT------SKRPFYSL------- 70
Cdd:PRK14963 4 LYQRARPITFDEVVGQEHV---KEVLLAALRQGrLGHAYLFSGPRGVGKTTTARLIAMAvncsgeDPKPCGECesclavr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 71 -----------SAINSGVKDVRDVIDK---AKQSGGlfttkNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTE 134
Cdd:PRK14963 81 rgahpdvleidAASNNSVEDVRDLREKvllAPLRGG-----RKVYILDEAHMMSKSAFNALLKTLEEppEHVIFILATTE 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1278483409 135 nPSfEVIPALLSRCQVYILNAFDKADLKALLNRALK-VDVELKQKQINL 182
Cdd:PRK14963 156 -PE-KMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEaEGREAEPEALQL 202
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
6-207 |
3.97e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 64.79 E-value: 3.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 6 AERIRPlvlEDFisqQHLVGKTGV---LTQSIAHGVI-PSLIFWGPPGIGKTTLAAIIA---NTSKRPFY---------- 68
Cdd:PRK06647 7 ATKRRP---RDF---NSLEGQDFVvetLKHSIESNKIaNAYIFSGPRGVGKTSSARAFArclNCVNGPTPmpcgecssck 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 69 ------SLSAI------NSGVKDVRDVIDKAkqsggLF---TTKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGA 131
Cdd:PRK06647 81 sidndnSLDVIeidgasNTSVQDVRQIKEEI-----MFppaSSRYRVYIIDEVHMLSNSAFNALLKTIEEppPYIVFIFA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 132 TTEnpsFEVIPALL-SRCQVYilnAFDKADLKALLNRALKVDVELKQKQinlkETEALIHL---SGGDARKLLNIFELVI 207
Cdd:PRK06647 156 TTE---VHKLPATIkSRCQHF---NFRLLSLEKIYNMLKKVCLEDQIKY----EDEALKWIaykSTGSVRDAYTLFDQVV 225
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
1-201 |
7.08e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 63.69 E-value: 7.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 1 MNTPLAERIRPLVLEDFISQQHLVG--KTGVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIANT---------------- 62
Cdd:PRK14953 2 MYIPFARKYRPKFFKEVIGQEIVVRilKNAVKLQRVSH----AYIFAGPRGTGKTTIARILAKVlnclnpqegepcgkce 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 63 -----SKRPFYSL----SAINSGVKDVRDVIDKAkqSGGLFTTKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGA 131
Cdd:PRK14953 78 ncveiDKGSFPDLieidAASNRGIDDIRALRDAV--SYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEppPRTIFILC 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1278483409 132 TTEnpSFEVIPALLSRCQVYILNAFDKADLKALLNRAlkvdveLKQKQINLKE--TEALIHLSGG---DARKLLN 201
Cdd:PRK14953 156 TTE--YDKIPPTILSRCQRFIFSKPTKEQIKEYLKRI------CNEEKIEYEEkaLDLLAQASEGgmrDAASLLD 222
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
157-225 |
1.56e-10 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 56.87 E-value: 1.56e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278483409 157 DKADLKALLNRALKVDVELKQKQINLKE--TEALIHLSGGDARKLLNIFELVIG---QNTKIDITNELVLKAIQ 225
Cdd:cd18139 2 SEEDLEKLLKRALEDKERGGDRKVTIDDeaLELLAEAADGDARSALNLLELAVLsaeEDGGIVITLEDLEEVLQ 75
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
5-341 |
3.34e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 62.03 E-value: 3.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLVG--KTGVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIAN-------TSKRP--------- 66
Cdd:PRK08691 6 LARKWRPKTFADLVGQEHVVKalQNALDEGRLHH----AYLLTGTRGVGKTTIARILAKslncenaQHGEPcgvcqsctq 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 67 -----FYSL----SAINSGVKDVRDVIDKAKQSGGLFTTKnpILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTEN 135
Cdd:PRK08691 82 idagrYVDLleidAASNTGIDNIREVLENAQYAPTAGKYK--VYIIDEVHMLSKSAFNAMLKTLEEppEHVKFILATTDP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 136 PSFEVipALLSRCQVYILN--------------------AFDKADLkALLNRA----LKVDVELKQKQINL-----KETE 186
Cdd:PRK08691 160 HKVPV--TVLSRCLQFVLRnmtaqqvadhlahvldsekiAYEPPAL-QLLGRAaagsMRDALSLLDQAIALgsgkvAEND 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 187 ALIHLSGGDARKLLNIFELVIGQNtkiditNELVLKAIQQNPAR---YDKT-GE-----QHYDIISAFIKSIRGSDPNAA 257
Cdd:PRK08691 237 VRQMIGAVDKQYLYELLTGIINQD------GAALLAKAQEMAACavgFDNAlGElaillQQLALIQAVPSALAHDDPDSD 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 258 V-YWLARMIeGGEDVKF---IA---RRMLILASEDIGNANPTALII------ANNTFQAVSIIGNPESRIILSQCATYLA 324
Cdd:PRK08691 311 IlHRLAQTI-SGEQIQLyyqIAvhgKRDLSLAPDEYAGFMMTLLRMlafaplAAASCDANAVIENTELQSPSAQTAEKET 389
|
410 420
....*....|....*....|...
gi 1278483409 325 SS------PKSNASYTAISKAQE 341
Cdd:PRK08691 390 AAkkpqprPEAETAQTPVQTASA 412
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
3-201 |
3.81e-10 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 60.90 E-value: 3.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 3 TPLAERIRPLVLEDFISQQHLVGKTGVLTQSiahGVIPSLIFWGPPGIGKTTLAAIIANTSKRPFYS-----LSAINS-G 76
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARD---GNMPNLILSGPPGTGKTTSILALAHELLGPNYKeavleLNASDDrG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 77 VKDVRDVIDK-AKQSGGLFTTKNPILFIDEIHRFSKSQQDSLLGAVEkgwitLIGATTE-----NPSFEVIPALLSRCQV 150
Cdd:PLN03025 78 IDVVRNKIKMfAQKKVTLPPGRHKIVILDEADSMTSGAQQALRRTME-----IYSNTTRfalacNTSSKIIEPIQSRCAI 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1278483409 151 YilnAFDKADLKALLNRALKVdVELKQKQINLKETEALIHLSGGDARKLLN 201
Cdd:PLN03025 153 V---RFSRLSDQEILGRLMKV-VEAEKVPYVPEGLEAIIFTADGDMRQALN 199
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
2-169 |
7.68e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 60.85 E-value: 7.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 2 NTPLAERIRPLVLEDFISQQHLvgkTGVLTQSIAHG-VIPSLIFWGPPGIGKTTLAAIIA---NTSKRPFYSL------- 70
Cdd:PRK14959 3 HASLTARYRPQTFAEVAGQETV---KAILSRAAQENrVAPAYLFSGTRGVGKTTIARIFAkalNCETAPTGEPcntceqc 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 71 ---------------SAINSGVKD---VRDVIDKAKQSGglfttKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIG 130
Cdd:PRK14959 80 rkvtqgmhvdvveidGASNRGIDDakrLKEAIGYAPMEG-----RYKVFIIDEAHMLTREAFNALLKTLEEppARVTFVL 154
|
170 180 190
....*....|....*....|....*....|....*....
gi 1278483409 131 ATTENPSFEVipALLSRCQVYILNAFDKADLKALLNRAL 169
Cdd:PRK14959 155 ATTEPHKFPV--TIVSRCQHFTFTRLSEAGLEAHLTKVL 191
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
41-156 |
9.30e-10 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 57.00 E-value: 9.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 41 SLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAIN------------------------SGVKDVRDVIDKAKQSgglftt 96
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDgedileevldqllliivggkkasgSGELRLRLALALARKL------ 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278483409 97 KNPILFIDEIHRFSKSQQDSLLGAVEKGW----------ITLIGATteNPSFEVIPALL---SRCQVYILNAF 156
Cdd:smart00382 78 KPDVLILDEITSLLDAEQEALLLLLEELRlllllkseknLTVILTT--NDEKDLGPALLrrrFDRRIVLLLIL 148
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
7-201 |
9.48e-10 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 59.62 E-value: 9.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 7 ERIRPLVLEDFISQQHlVGKTgvLTQSIAHGVIPSLIFWGP-PGIGKTTLAAIIANTSKRPFYSLSAINSGVKDVRDVId 85
Cdd:PHA02544 13 QKYRPSTIDECILPAA-DKET--FKSIVKKGRIPNMLLHSPsPGTGKTTVAKALCNEVGAEVLFVNGSDCRIDFVRNRL- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 86 KAKQSGGLFTTKNPILFIDEIHRFSKSQ-QDSLLGAVEkgwitligATTENPSF--------EVIPALLSRCQVYILNAF 156
Cdd:PHA02544 89 TRFASTVSLTGGGKVIIIDEFDRLGLADaQRHLRSFME--------AYSKNCSFiitannknGIIEPLRSRCRVIDFGVP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1278483409 157 DKAD----LKALLNRALKVdveLKQKQI--NLKETEALIHLSGGDARKLLN 201
Cdd:PHA02544 161 TKEEqiemMKQMIVRCKGI---LEAEGVevDMKVLAALVKKNFPDFRRTIN 208
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
46-165 |
9.96e-10 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 57.24 E-value: 9.96e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 46 GPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKqsgglfttKNP--ILFIDEIHRFSKSQQDS 116
Cdd:cd19501 44 GPPGTGKTLLAKAVAGEAGVPFFSISGsdfvemfVGVGASRVRDLFEQAK--------KNApcIVFIDEIDAVGRKRGAG 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1278483409 117 LLGAVEKGWITLIGATTENPSFEvipallSRCQVYILNAFDKADL--KALL 165
Cdd:cd19501 116 LGGGHDEREQTLNQLLVEMDGFE------SNTGVIVIAATNRPDVldPALL 160
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
5-253 |
1.03e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 60.16 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQH--LVGKTGVLTQSIAHGvipsLIFWGPPGIGKTTLAAIIA---NTSKRPFY-------SLSA 72
Cdd:PRK14962 4 LYRKYRPKTFSEVVGQDHvkKLIINALKKNSISHA----YIFAGPRGTGKTTVARILAkslNCENRKGVepcnecrACRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 73 INSGV-KDVR----------DVIDKAKQSGGLFTT--KNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTeNPS 137
Cdd:PRK14962 80 IDEGTfMDVIeldaasnrgiDEIRKIRDAVGYRPMegKYKVYIIDEVHMLTKEAFNALLKTLEEppSHVVFVLATT-NLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 138 fEVIPALLSRCQVY-ILNAFDKADLKALLNRALKVDVELKQKQINLKETEAlihlSGGdARKLLNIFELVIGQNTKiDIT 216
Cdd:PRK14962 159 -KVPPTIISRCQVIeFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRA----SGG-LRDALTMLEQVWKFSEG-KIT 231
|
250 260 270
....*....|....*....|....*....|....*..
gi 1278483409 217 NELVLKAIQQNPArydktgeqhyDIISAFIKSIRGSD 253
Cdd:PRK14962 232 LETVHEALGLIPI----------EVVRDYINAIFNGD 258
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
10-206 |
1.89e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 59.83 E-value: 1.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 10 RPLVLEDFISQQHLVG--KTGVLTQSIAHGvipsLIFWGPPGIGKTTLAAIIANT----------------SKRPFYSLS 71
Cdd:PRK07133 13 RPKTFDDIVGQDHIVQtlKNIIKSNKISHA----YLFSGPRGTGKTSVAKIFANAlncshktdllepcqecIENVNNSLD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 72 AI------NSGVKDVRDVIDKAKQSGglFTTKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTENpsfEVIP- 142
Cdd:PRK07133 89 IIemdaasNNGVDEIRELIENVKNLP--TQSKYKIYIIDEVHMLSKSAFNALLKTLEEppKHVIFILATTEV---HKIPl 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278483409 143 ALLSRCQVYilnAFDKADLKALLNRALKVdveLKQKQINLkETEALI---HLSGGDARKLLNIFELV 206
Cdd:PRK07133 164 TILSRVQRF---NFRRISEDEIVSRLEFI---LEKENISY-EKNALKliaKLSSGSLRDALSIAEQV 223
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
4-286 |
2.71e-09 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 58.78 E-value: 2.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 4 PLAERIRPLVLEDfisqqhLVGKTGVLTQ------SIAHGVIP-SLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAINSG 76
Cdd:PRK04195 3 PWVEKYRPKTLSD------VVGNEKAKEQlrewieSWLKGKPKkALLLYGPPGVGKTSLAHALANDYGWEVIELNASDQR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 77 VKDV-RDVIDKAKQSGGLFTTKNPILFIDE---IHrfskSQQDSllGAVEKgwITLIGATTENPsfevIpallsrcqVYI 152
Cdd:PRK04195 77 TADViERVAGEAATSGSLFGARRKLILLDEvdgIH----GNEDR--GGARA--ILELIKKAKQP----I--------ILT 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 153 LNAFDKADLKALLNRALkvDVELKQ----------KQINLKE-----TEALIHL---SGGDARKLLNIFELVIGQNTKID 214
Cdd:PRK04195 137 ANDPYDPSLRELRNACL--MIEFKRlstrsivpvlKRICRKEgiecdDEALKEIaerSGGDLRSAINDLQAIAEGYGKLT 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 215 ITN--ELVLKAIQQNPARY-DKT-GEQHYDIIsafIKSIRGSD--PNAAVYWLA----RMIEGGEDvkfIARRMLILASE 284
Cdd:PRK04195 215 LEDvkTLGRRDREESIFDAlDAVfKARNADQA---LEASYDVDedPDDLIEWIDenipKEYDDPED---IARAYDALSRA 288
|
..
gi 1278483409 285 DI 286
Cdd:PRK04195 289 DI 290
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
43-145 |
7.89e-09 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 54.60 E-value: 7.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 43 IFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSgglfttKNPILFIDEI--------H 107
Cdd:cd19511 31 LLYGPPGCGKTLLAKALASEAGLNFISVKGpelfskyVGESERAVREIFQKARQA------APCIIFFDEIdslaprrgQ 104
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1278483409 108 RFSKSQQDSLL--------GAVEKGWITLIGATteNPSFEVIPALL 145
Cdd:cd19511 105 SDSSGVTDRVVsqllteldGIESLKGVVVIAAT--NRPDMIDPALL 148
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
4-226 |
7.94e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 57.56 E-value: 7.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 4 PLAERIRPLVLEDFISQQHLVGktgVLTQSIAHGVIP-SLIFWGPPGIGKTTLAAIIANT---------SKRPFYSLSAI 73
Cdd:PRK06645 10 PFARKYRPSNFAELQGQEVLVK---VLSYTILNDRLAgGYLLTGIRGVGKTTSARIIAKAvncsaliteNTTIKTCEQCT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 74 N--------------------SGVKDVRDVIDKAKQSGglFTTKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGA 131
Cdd:PRK06645 87 NcisfnnhnhpdiieidaaskTSVDDIRRIIESAEYKP--LQGKHKIFIIDEVHMLSKGAFNALLKTLEEppPHIIFIFA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 132 TTEnpsFEVIPA-LLSRCQVYILNAFDKADLKALLnralkvdvELKQKQINLKET-EAL---IHLSGGDARKLLNIFELV 206
Cdd:PRK06645 165 TTE---VQKIPAtIISRCQRYDLRRLSFEEIFKLL--------EYITKQENLKTDiEALriiAYKSEGSARDAVSILDQA 233
|
250 260
....*....|....*....|
gi 1278483409 207 IGQNTKIDitNELVLKAIQQ 226
Cdd:PRK06645 234 ASMSAKSD--NIISPQVINQ 251
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
5-149 |
1.29e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 57.06 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHlVGKT---GVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIAN-------------------- 61
Cdd:PRK14965 6 LARKYRPQTFSDLTGQEH-VSRTlqnAIDTGRVAH----AFLFTGARGVGKTSTARILAKalnceqgltaepcnvcppcv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 62 -----TSKRPFYSLSAINSGVKDVRDVIDKAKQSGGLFTTKnpILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTE 134
Cdd:PRK14965 81 eitegRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYK--IFIIDEVHMLSTNAFNALLKTLEEppPHVKFIFATTE 158
|
170
....*....|....*
gi 1278483409 135 npSFEVIPALLSRCQ 149
Cdd:PRK14965 159 --PHKVPITILSRCQ 171
|
|
| RecA-like_CDC48_r2-like |
cd19528 |
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
37-120 |
1.61e-08 |
|
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 53.67 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 37 GVIPS--LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSGglfttknP-ILFIDEI 106
Cdd:cd19528 23 GMTPSkgVLFYGPPGCGKTLLAKAIANECQANFISVKGpelltmwFGESEANVRDIFDKARAAA-------PcVLFFDEL 95
|
90
....*....|....
gi 1278483409 107 HRFSKSQQDSLLGA 120
Cdd:cd19528 96 DSIAKARGGNIGDA 109
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
35-106 |
2.36e-08 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 55.40 E-value: 2.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 35 AHGVIP--SLIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQsgglfttKNP-ILFID 104
Cdd:COG1222 106 KYGIEPpkGVLLYGPPGTGKTLLAKAVAGELGAPFIRVRGselvskyIGEGARNVREVFELARE-------KAPsIIFID 178
|
..
gi 1278483409 105 EI 106
Cdd:COG1222 179 EI 180
|
|
| RecA-like_Lon |
cd19500 |
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ... |
40-114 |
2.54e-08 |
|
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410908 [Multi-domain] Cd Length: 182 Bit Score: 53.33 E-value: 2.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 40 PSLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAinSGVKDVRD---------------VIDKAKQSGglftTKNPILFID 104
Cdd:cd19500 38 PILCLVGPPGVGKTSLGKSIARALGRKFVRISL--GGVRDEAEirghrrtyvgampgrIIQALKKAG----TNNPVFLLD 111
|
90
....*....|
gi 1278483409 105 EIHRFSKSQQ 114
Cdd:cd19500 112 EIDKIGSSFR 121
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
42-106 |
5.64e-08 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 51.91 E-value: 5.64e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLS--AINSGV-----KDVRDVIDKAKQsgglftTKNPILFIDEI 106
Cdd:cd19503 37 VLLHGPPGTGKTLLARAVANEAGANFLSISgpSIVSKYlgeseKNLREIFEEARS------HAPSIIFIDEI 102
|
|
| hflB |
PRK10733 |
ATP-dependent zinc metalloprotease FtsH; |
37-139 |
6.67e-08 |
|
ATP-dependent zinc metalloprotease FtsH;
Pssm-ID: 182683 [Multi-domain] Cd Length: 644 Bit Score: 54.66 E-value: 6.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 37 GVIPS-LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSGGLfttknpILFIDEIHR 108
Cdd:PRK10733 182 GKIPKgVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGsdfvemfVGVGASRVRDMFEQAKKAAPC------IIFIDEIDA 255
|
90 100 110
....*....|....*....|....*....|.
gi 1278483409 109 FSKSQQDSLLGAVEKGWITLIGATTENPSFE 139
Cdd:PRK10733 256 VGRQRGAGLGGGHDEREQTLNQMLVEMDGFE 286
|
|
| ftsH |
CHL00176 |
cell division protein; Validated |
39-224 |
7.07e-08 |
|
cell division protein; Validated
Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 54.67 E-value: 7.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 39 IPS-LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQsgglfttKNP-ILFIDEIHRF 109
Cdd:CHL00176 215 IPKgVLLVGPPGTGKTLLAKAIAGEAEVPFFSISGsefvemfVGVGAARVRDLFKKAKE-------NSPcIVFIDEIDAV 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 110 SKSQQDSLLGAVEKGWITLIGATTENPSFE-----VIPALLSRcqVYILNA-------FDKADLKALLNRALKVD---VE 174
Cdd:CHL00176 288 GRQRGAGIGGGNDEREQTLNQLLTEMDGFKgnkgvIVIAATNR--VDILDAallrpgrFDRQITVSLPDREGRLDilkVH 365
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1278483409 175 LKQKQINLKETEALIH-----LSGGDARKLLNIFELVIGQNTKIDITNELVLKAI 224
Cdd:CHL00176 366 ARNKKLSPDVSLELIArrtpgFSGADLANLLNEAAILTARRKKATITMKEIDTAI 420
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
5-148 |
8.28e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 54.37 E-value: 8.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLV-GKTGVLTQSIAHGvipSLIFWGPPGIGKTTLAAIIANT-------SKRP---------- 66
Cdd:PRK14969 6 LARKWRPKSFSELVGQEHVVrALTNALEQQRLHH---AYLFTGTRGVGKTTLARILAKSlncetgvTATPcgvcsaclei 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 67 ----FYSL----SAINSGVKDVRDVIDKAKQS--GGLFTtknpILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTE 134
Cdd:PRK14969 83 dsgrFVDLievdAASNTQVDAMRELLDNAQYAptRGRFK----VYIIDEVHMLSKSAFNAMLKTLEEppEHVKFILATTD 158
|
170
....*....|....*
gi 1278483409 135 nPsfEVIP-ALLSRC 148
Cdd:PRK14969 159 -P--QKIPvTVLSRC 170
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
5-256 |
9.04e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 54.32 E-value: 9.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLVGKT--GVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIAN--------------------- 61
Cdd:PRK14957 6 LARKYRPQSFAEVAGQQHALNSLvhALETQKVHH----AYLFTGTRGVGKTTLGRLLAKclncktgvtaepcnkcencva 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 62 TSKRPFYSL----SAINSGVKDVRDVIDKAK--QSGGLFTtknpILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATT 133
Cdd:PRK14957 82 INNNSFIDLieidAASRTGVEETKEILDNIQymPSQGRYK----VYLIDEVHMLSKQSFNALLKTLEEppEYVKFILATT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 134 EnpsFEVIP-ALLSRCQVYILNAFDKADLKALLNralkvdVELKQKQINLKET--EALIHLSGGDARKLLNIFELVIGQn 210
Cdd:PRK14957 158 D---YHKIPvTILSRCIQLHLKHISQADIKDQLK------IILAKENINSDEQslEYIAYHAKGSLRDALSLLDQAISF- 227
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1278483409 211 tkidITNELVLKAIQQNPARYDKtgEQHYDIISAFIKsirgSDPNA 256
Cdd:PRK14957 228 ----CGGELKQAQIKQMLGIIDS--EEVYSIINAIID----NDPKA 263
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
7-226 |
8.10e-07 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 50.76 E-value: 8.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 7 ERIRPLVLEDFISQQHLVGktgVLTQSIAHGVIPSLIFWGPPGIGKTT----LAA-----------IIANTS------KR 65
Cdd:PRK12402 7 EKYRPALLEDILGQDEVVE---RLSRAVDSPNLPHLLVQGPPGSGKTAavraLARelygdpwennfTEFNVAdffdqgKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 66 PFYS----LSAINSGVKDVRDVIDKAKQSGGLFTTKNPI------LFIDEIHRFSKSQQDSLLGAVEKGWIT--LIGATT 133
Cdd:PRK12402 84 YLVEdprfAHFLGTDKRIRSSKIDNFKHVLKEYASYRPLsadyktILLDNAEALREDAQQALRRIMEQYSRTcrFIIATR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 134 eNPSfEVIPALLSRC-QVYILnAFDKADLKALLNRAlkvdVELKQKQINLKETEALIHLSGGDARKLLNIFELVIGQNTK 212
Cdd:PRK12402 164 -QPS-KLIPPIRSRClPLFFR-APTDDELVDVLESI----AEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGE 236
|
250
....*....|....
gi 1278483409 213 idITNELVLKAIQQ 226
Cdd:PRK12402 237 --ITMEAAYEALGD 248
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
1-217 |
9.76e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 50.94 E-value: 9.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 1 MNtpLAERIRPLVLEDFISQQHLVGktgVLTQSIAHGVIP-SLIFWGPPGIGKTTLAAIIA---NTSKRPFYS------- 69
Cdd:PRK14964 1 MN--LALKYRPSSFKDLVGQDVLVR---ILRNAFTLNKIPqSILLVGASGVGKTTCARIISlclNCSNGPTSDpcgtchn 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 70 -LS--------------AINSGVKDVRDVIDKAKQSGglFTTKNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGAT 132
Cdd:PRK14964 76 cISiknsnhpdvieidaASNTSVDDIKVILENSCYLP--ISSKFKVYIIDEVHMLSNSAFNALLKTLEEpaPHVKFILAT 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 133 TEnpsFEVIP-ALLSRCQVYILNAFDKADLKALLNralkvDVELKQKQINLKETEALI-HLSGGDARKLLNIFE-LVIGQ 209
Cdd:PRK14964 154 TE---VKKIPvTIISRCQRFDLQKIPTDKLVEHLV-----DIAKKENIEHDEESLKLIaENSSGSMRNALFLLEqAAIYS 225
|
....*...
gi 1278483409 210 NTKIDITN 217
Cdd:PRK14964 226 NNKISEKS 233
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
1-191 |
1.11e-06 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 49.78 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 1 MNTplaERIRPLVLEDFISQQHLVgkTGVLTQSIAHGviPSLIfWGPPGIGKTTLAAIIANTSKRPFYSLsAINSGVK-- 78
Cdd:COG0714 1 MTE---ARLRAEIGKVYVGQEELI--ELVLIALLAGG--HLLL-EGVPGVGKTTLAKALARALGLPFIRI-QFTPDLLps 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 79 DV--RDVIDKAKQS-----GGLFTtknPILFIDEIHR----FsksqQDSLLGAVEKGWITLIGAT-----------TENP 136
Cdd:COG0714 72 DIlgTYIYDQQTGEfefrpGPLFA---NVLLADEINRappkT----QSALLEAMEERQVTIPGGTyklpepflviaTQNP 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1278483409 137 S-----FEVIPALLSRCQVYILNAF-DKADLKALLNRALKVDVELKQKQINLKETEALIHL 191
Cdd:COG0714 145 IeqegtYPLPEAQLDRFLLKLYIGYpDAEEEREILRRHTGRHLAEVEPVLSPEELLALQEL 205
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
46-106 |
1.68e-06 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 49.83 E-value: 1.68e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1278483409 46 GPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQsgglfttKNP-ILFIDEI 106
Cdd:PRK03992 172 GPPGTGKTLLAKAVAHETNATFIRVVGselvqkfIGEGARLVRELFELARE-------KAPsIIFIDEI 233
|
|
| RecA-like_NVL_r2-like |
cd19530 |
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
42-161 |
2.34e-06 |
|
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410938 [Multi-domain] Cd Length: 161 Bit Score: 47.48 E-value: 2.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA---INSGVKD----VRDVIDKAKQSgglfttkNP-ILFIDEIHRFSKSQ 113
Cdd:cd19530 33 VLLYGPPGCGKTLLAKAVANESGANFISVKGpelLNKYVGEseraVRQVFQRARAS-------APcVIFFDEVDALVPKR 105
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1278483409 114 QDSLLGAVEKGWITLIgatTEnpsfevIPALLSRCQVYILNAFDKADL 161
Cdd:cd19530 106 GDGGSWASERVVNQLL---TE------MDGLEERSNVFVIAATNRPDI 144
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
5-154 |
2.49e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 49.39 E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLVG--KTGVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIAN-----------------TSKR 65
Cdd:PRK06305 7 SSRKYRPQTFSEILGQDAVVAvlKNALRFNRAAH----AYLFSGIRGTGKTTLARIFAKalncqnptedqepcnqcASCK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 66 PFYSLS---------AINSGVKDVRDVIDKAkqsggLFTT---KNPILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGA 131
Cdd:PRK06305 83 EISSGTsldvleidgASHRGIEDIRQINETV-----LFTPsksRYKIYIIDEVHMLTKEAFNSLLKTLEEppQHVKFFLA 157
|
170 180
....*....|....*....|...
gi 1278483409 132 TTENpsFEVIPALLSRCQVYILN 154
Cdd:PRK06305 158 TTEI--HKIPGTILSRCQKMHLK 178
|
|
| RecA-like_VPS4-like |
cd19509 |
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ... |
41-119 |
3.33e-06 |
|
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410917 [Multi-domain] Cd Length: 163 Bit Score: 46.96 E-value: 3.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 41 SLIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQsgglftTKNPILFIDEIhrfsksq 113
Cdd:cd19509 34 GILLYGPPGTGKTLLARAVASESGSTFFSISAsslvskwVGESEKIVRALFALARE------LQPSIIFIDEI------- 100
|
....*.
gi 1278483409 114 qDSLLG 119
Cdd:cd19509 101 -DSLLS 105
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
1-61 |
7.36e-06 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 48.30 E-value: 7.36e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278483409 1 MNTPLAERIRPLVLEDFISQQHLVGKtgvLTQSIAHGVIPSLIFWGPPGIGK--TTLAAIIAN 61
Cdd:PRK04132 5 LEKPWVEKYRPQRLDDIVGQEHIVKR---LKHYVKTGSMPHLLFAGPPGVGKclTGDTKVIAN 64
|
|
| HflB |
COG0465 |
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; |
46-106 |
7.97e-06 |
|
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440233 [Multi-domain] Cd Length: 583 Bit Score: 48.11 E-value: 7.97e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278483409 46 GPPGIGKTTLAAIIANTSKRPFYSLSAinS---------GVKDVRDVIDKAKqsgglfttKN-P-ILFIDEI 106
Cdd:COG0465 182 GPPGTGKTLLAKAVAGEAGVPFFSISG--SdfvemfvgvGASRVRDLFEQAK--------KNaPcIIFIDEI 243
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
10-279 |
1.26e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 47.56 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 10 RPLVLEDFISQQHLVgKT---GVLTQSIAHgvipSLIFWGPPGIGKTTLAAIIA-----------------------NTS 63
Cdd:PRK05563 11 RPQTFEDVVGQEHIT-KTlknAIKQGKISH----AYLFSGPRGTGKTSAAKIFAkavnclnppdgepcneceickaiTNG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 64 krpfySLS-------AINSGVKDVRDVIDKAKQSGGLFTTKNPIlfIDEIHRFSKSQQDSLLgaveKgwiTL-------- 128
Cdd:PRK05563 86 -----SLMdvieidaASNNGVDEIRDIRDKVKYAPSEAKYKVYI--IDEVHMLSTGAFNALL----K---TLeeppahvi 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 129 -IGATTEnPsfEVIPA-LLSRCQVYilnAFDKADLKALLNRALKVdveLKQKQINLKEtEAL----IHLSGG--DArklL 200
Cdd:PRK05563 152 fILATTE-P--HKIPAtILSRCQRF---DFKRISVEDIVERLKYI---LDKEGIEYED-EALrliaRAAEGGmrDA---L 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 201 NIFELVI--GQNTkidITNELVLkaiqqnparyDKTGEQHYDIISAFIKSIRGSDPNAAVYWLARMIEGGEDVKFIARRM 278
Cdd:PRK05563 219 SILDQAIsfGDGK---VTYEDAL----------EVTGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDL 285
|
.
gi 1278483409 279 L 279
Cdd:PRK05563 286 I 286
|
|
| RecA-like_PAN_like |
cd19502 |
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ... |
37-120 |
1.51e-05 |
|
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410910 [Multi-domain] Cd Length: 171 Bit Score: 45.02 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 37 GVIP--SLIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQsgglfttKNP-ILFIDEI 106
Cdd:cd19502 33 GIEPpkGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGselvqkyIGEGARLVRELFEMARE-------KAPsIIFIDEI 105
|
90
....*....|....
gi 1278483409 107 HRFSKSQQDSLLGA 120
Cdd:cd19502 106 DAIGAKRFDSGTGG 119
|
|
| RecA-like_VCP_r2 |
cd19529 |
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ... |
37-145 |
1.68e-05 |
|
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410937 [Multi-domain] Cd Length: 159 Bit Score: 44.79 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 37 GVIPS--LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSGglfttknP-ILFIDEI 106
Cdd:cd19529 23 GIRPPkgILLYGPPGTGKTLLAKAVATESNANFISVKGpellskwVGESEKAIREIFRKARQVA-------PcVIFFDEI 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1278483409 107 ----------------HRFSKSQQDSLLGAVEKGWITLIGATTEnPsfEVI-PALL 145
Cdd:cd19529 96 dsiaprrgttgdsgvtERVVNQLLTELDGLEEMNGVVVIAATNR-P--DIIdPALL 148
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
5-207 |
2.74e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 45.96 E-value: 2.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLVGktgVLTQSIAHGVIP-SLIFWGPPGIGKTTLAAIIANT--------------------- 62
Cdd:PRK14961 6 LARKWRPQYFRDIIGQKHIVT---AISNGLSLGRIHhAWLLSGTRGVGKTTIARLLAKSlncqngitsnpcrkciickei 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 63 SKRPFYSLSAINSG----VKDVRDVIDKAK--QSGGLFTtknpILFIDEIHRFSKSQQDSLLGAVEKG--WITLIGATTE 134
Cdd:PRK14961 83 EKGLCLDLIEIDAAsrtkVEEMREILDNIYysPSKSRFK----VYLIDEVHMLSRHSFNALLKTLEEPpqHIKFILATTD 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278483409 135 npsFEVIP-ALLSRCQVYILNAFDKADLKALLNRALKvdvelkqKQINLKETEALIHLS---GGDARKLLNIFELVI 207
Cdd:PRK14961 159 ---VEKIPkTILSRCLQFKLKIISEEKIFNFLKYILI-------KESIDTDEYALKLIAyhaHGSMRDALNLLEHAI 225
|
|
| RecA-like_Figl-1 |
cd19525 |
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ... |
42-116 |
3.25e-05 |
|
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410933 [Multi-domain] Cd Length: 186 Bit Score: 44.59 E-value: 3.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKqsgglftTKNP-ILFIDEIHRFSKSQ 113
Cdd:cd19525 58 ILLFGPPGTGKTLIGKCIASQSGATFFSISAssltskwVGEGEKMVRALFSVAR-------CKQPaVIFIDEIDSLLSQR 130
|
...
gi 1278483409 114 QDS 116
Cdd:cd19525 131 GEG 133
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
37-145 |
4.06e-05 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 46.05 E-value: 4.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 37 GVIP--SLIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSGglfttkNPILFIDEI- 106
Cdd:TIGR01243 483 GIRPpkGVLLFGPPGTGKTLLAKAVATESGANFIAVRGpeilskwVGESEKAIREIFRKARQAA------PAIIFFDEId 556
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1278483409 107 -------HRFSKSQQDSLL--------GAVEKGWITLIGATTENPSFEviPALL 145
Cdd:TIGR01243 557 aiapargARFDTSVTDRIVnqlltemdGIQELSNVVVIAATNRPDILD--PALL 608
|
|
| RecA-like_PEX6_r2 |
cd19527 |
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ... |
42-106 |
7.76e-05 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410935 [Multi-domain] Cd Length: 160 Bit Score: 42.89 E-value: 7.76e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSgglfttKNPILFIDEI 106
Cdd:cd19527 29 ILLYGPPGTGKTLLAKAIATECSLNFLSVKGpelinmyIGESEANVREVFQKARDA------KPCVIFFDEL 94
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
41-148 |
1.05e-04 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 41.89 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 41 SLIFWGPPGIGKTTLAAIIAN-TSKRP---------------FYSLSAINSGVKDVRDVIDKAKQSGGlfttknpILFID 104
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAaLSNRPvfyvqltrdtteedlFGRRNIDPGGASWVDGPLVRAAREGE-------IAVLD 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278483409 105 EIHRFSKSQQDSLLGAVEKGWITLIGATTE----NPSFEVI--------------PALLSRC 148
Cdd:pfam07728 74 EINRANPDVLNSLLSLLDERRLLLPDGGELvkaaPDGFRLIatmnpldrglnelsPALRSRF 135
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
1-153 |
1.56e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 43.88 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 1 MNTPLAERIRPLVLEDFISQQHLvgkTGVLTQSIAHGVIP-SLIFWGPPGIGKTTLAAIIA----------NTSKRPFYS 69
Cdd:PRK14960 1 MYQVLARKYRPRNFNELVGQNHV---SRALSSALERGRLHhAYLFTGTRGVGKTTIARILAkclncetgvtSTPCEVCAT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 70 LSAINSG---------------VKDVRDVIDKA--KQSGGLFTtknpILFIDEIHRFSKSQQDSLLGAVEK--GWITLIG 130
Cdd:PRK14960 78 CKAVNEGrfidlieidaasrtkVEDTRELLDNVpyAPTQGRFK----VYLIDEVHMLSTHSFNALLKTLEEppEHVKFLF 153
|
170 180
....*....|....*....|...
gi 1278483409 131 ATTENPSFEVipALLSRCQVYIL 153
Cdd:PRK14960 154 ATTDPQKLPI--TVISRCLQFTL 174
|
|
| RecA-like_VPS4 |
cd19521 |
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ... |
42-120 |
2.68e-04 |
|
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410929 [Multi-domain] Cd Length: 170 Bit Score: 41.39 E-value: 2.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSgglfttKNPILFIDEIhrfsksqq 114
Cdd:cd19521 43 ILLYGPPGTGKSYLAKAVATEANSTFFSVSSsdlvskwMGESEKLVKQLFAMAREN------KPSIIFIDEV-------- 108
|
....*.
gi 1278483409 115 DSLLGA 120
Cdd:cd19521 109 DSLCGT 114
|
|
| RecA-like_spastin |
cd19524 |
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ... |
42-118 |
2.70e-04 |
|
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410932 [Multi-domain] Cd Length: 164 Bit Score: 41.37 E-value: 2.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQsgglftTKNPILFIDEIhrfsksqq 114
Cdd:cd19524 36 LLLFGPPGNGKTMLAKAVAAESNATFFNISAasltskyVGEGEKLVRALFAVARE------LQPSIIFIDEV-------- 101
|
....
gi 1278483409 115 DSLL 118
Cdd:cd19524 102 DSLL 105
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
5-217 |
2.84e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 43.18 E-value: 2.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 5 LAERIRPLVLEDFISQQHLV-GKTGVLTQSIAHGvipSLIFWGPPGIGKTTLAAIIAN-------TSKRP---------- 66
Cdd:PRK14958 6 LARKWRPRCFQEVIGQAPVVrALSNALDQQYLHH---AYLFTGTRGVGKTTISRILAKclncekgVSANPcndcencrei 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 67 --------FYSLSAINSGVKDVRDVIDKA--KQSGGLFTtknpILFIDEIHRFSKSQQDSLLGAVEK--GWITLIGATTE 134
Cdd:PRK14958 83 degrfpdlFEVDAASRTKVEDTRELLDNIpyAPTKGRFK----VYLIDEVHMLSGHSFNALLKTLEEppSHVKFILATTD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 135 NPSFEVipALLSRCQVYILNAFDKADLKALLNRALKVD-VELKQKQINLketeaLIHLSGGDARKLLNIFELVIGQ-NTK 212
Cdd:PRK14958 159 HHKLPV--TVLSRCLQFHLAQLPPLQIAAHCQHLLKEEnVEFENAALDL-----LARAANGSVRDALSLLDQSIAYgNGK 231
|
....*
gi 1278483409 213 IDITN 217
Cdd:PRK14958 232 VLIAD 236
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
42-144 |
4.52e-04 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 42.59 E-value: 4.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSGglfttkNPILFIDEIHRFSkSQQ 114
Cdd:TIGR01243 215 VLLYGPPGTGKTLLAKAVANEAGAYFISINGpeimskyYGESEERLREIFKEAEENA------PSIIFIDEIDAIA-PKR 287
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1278483409 115 DSLLGAVEK----------------GWITLIGATTENPSFEviPAL 144
Cdd:TIGR01243 288 EEVTGEVEKrvvaqlltlmdglkgrGRVIVIGATNRPDALD--PAL 331
|
|
| PRK05818 |
PRK05818 |
DNA polymerase III subunit delta'; Validated |
98-214 |
4.59e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 235618 [Multi-domain] Cd Length: 261 Bit Score: 41.74 E-value: 4.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 98 NPILFIDEIHRFSKSQQDSLLGAVEKGWITLIGA-TTENPSFeVIPALLSRCQVYILNAFDKadlkallnralKVDVELK 176
Cdd:PRK05818 89 KKIYIIYGIEKLNKQSANSLLKLIEEPPKNTYGIfTTRNENN-ILNTILSRCVQYVVLSKEK-----------KVPFKVE 156
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1278483409 177 QKQINLKET--------EALIHLSGGDARKLLNIFELVIGQNTKID 214
Cdd:PRK05818 157 SNDRYFQYIllsfysvdEQLQAYNNGSFSKLKNIIETLINKKNKLI 202
|
|
| RecA-like_CDC48_r1-like |
cd19519 |
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ... |
37-123 |
8.64e-04 |
|
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410927 [Multi-domain] Cd Length: 166 Bit Score: 39.73 E-value: 8.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 37 GVIP--SLIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQsgglfttKNP-ILFIDEI 106
Cdd:cd19519 30 GIKPprGILLYGPPGTGKTLIARAVANETGAFFFLINGpeimsklAGESESNLRKAFEEAEK-------NAPaIIFIDEI 102
|
90
....*....|....*..
gi 1278483409 107 HRFSKSQQDSlLGAVEK 123
Cdd:cd19519 103 DAIAPKREKT-HGEVER 118
|
|
| PRK10787 |
PRK10787 |
DNA-binding ATP-dependent protease La; Provisional |
7-110 |
1.26e-03 |
|
DNA-binding ATP-dependent protease La; Provisional
Pssm-ID: 182730 [Multi-domain] Cd Length: 784 Bit Score: 41.08 E-value: 1.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 7 ERIRPLVLEdFISQQHLVGKTgvltqsiaHGviPSLIFWGPPGIGKTTLAAIIANTSKRPFYSLSAinSGVKDVRDV--- 83
Cdd:PRK10787 328 ERVKDRILE-YLAVQSRVNKI--------KG--PILCLVGPPGVGKTSLGQSIAKATGRKYVRMAL--GGVRDEAEIrgh 394
|
90 100 110
....*....|....*....|....*....|....*....
gi 1278483409 84 ------------IDKAKQSGglftTKNPILFIDEIHRFS 110
Cdd:PRK10787 395 rrtyigsmpgklIQKMAKVG----VKNPLFLLDEIDKMS 429
|
|
| HerA |
COG0433 |
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase ... |
69-164 |
1.44e-03 |
|
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains [Replication, recombination and repair];
Pssm-ID: 440202 [Multi-domain] Cd Length: 388 Bit Score: 40.75 E-value: 1.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 69 SLSAINSGVKDV------RDVIDKAKQSGGLFTTKNPI-LFIDEIHRFSKSQQDSLLGAVE--------KGwITLIGAtT 133
Cdd:COG0433 223 DLSGLPEELQSTfvlwllRELFEARPEVGDADDRKLPLvLVIDEAHLLAPAAPSALLEILEriaregrkFG-VGLILA-T 300
|
90 100 110
....*....|....*....|....*....|..
gi 1278483409 134 ENPSfEVIPALLSRCQVYI-LNAFDKADLKAL 164
Cdd:COG0433 301 QRPS-DIDEDVLSQLGTQIiLRLFNPRDQKAV 331
|
|
| RecA-like_PEX1_r2 |
cd19526 |
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ... |
42-105 |
1.55e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410934 [Multi-domain] Cd Length: 158 Bit Score: 38.95 E-value: 1.55e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKqsgglfTTKNPILFIDE 105
Cdd:cd19526 30 ILLYGPPGCGKTLLASAIASECGLNFISVKGpellnkyIGASEQNVRDLFSRAQ------SAKPCILFFDE 94
|
|
| Lon |
COG0466 |
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, ... |
7-106 |
1.73e-03 |
|
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440234 [Multi-domain] Cd Length: 785 Bit Score: 40.77 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 7 ERIrplvLEdFISQQHLVGKtgvLTQSIahgvipsLIFWGPPGIGKTTLAAIIANTSKRPFY--SLsainSGVKDV---- 80
Cdd:COG0466 335 ERI----LE-YLAVRKLKKK---LKGPI-------LCLVGPPGVGKTSLGKSIARALGRKFVriSL----GGVRDEaeir 395
|
90 100 110
....*....|....*....|....*....|....*...
gi 1278483409 81 ------------RdVIDKAKQSGglftTKNPILFIDEI 106
Cdd:COG0466 396 ghrrtyigampgR-IIQGLKKAG----TKNPVFLLDEI 428
|
|
| PRK08116 |
PRK08116 |
hypothetical protein; Validated |
42-61 |
3.15e-03 |
|
hypothetical protein; Validated
Pssm-ID: 236153 [Multi-domain] Cd Length: 268 Bit Score: 39.23 E-value: 3.15e-03
|
| COG5545 |
COG5545 |
Predicted P-loop ATPase and inactivated derivatives [Mobilome: prophages, transposons]; |
42-127 |
3.24e-03 |
|
Predicted P-loop ATPase and inactivated derivatives [Mobilome: prophages, transposons];
Pssm-ID: 444288 [Multi-domain] Cd Length: 615 Bit Score: 39.67 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIAntsKRPFYSLSAINSGVKDVRDVIdkakqsgglftTKNPILFIDEIHRFSKSQQDSLlgav 121
Cdd:COG5545 359 LVLVGPQGIGKSTFLRILA---GPEWFSDSLSDLDDKDAAEKL-----------QGNWIIELDELDALSKADVEAL---- 420
|
....*.
gi 1278483409 122 eKGWIT 127
Cdd:COG5545 421 -KAFLS 425
|
|
| PTZ00454 |
PTZ00454 |
26S protease regulatory subunit 6B-like protein; Provisional |
42-120 |
3.41e-03 |
|
26S protease regulatory subunit 6B-like protein; Provisional
Pssm-ID: 240423 [Multi-domain] Cd Length: 398 Bit Score: 39.36 E-value: 3.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSA-------INSGVKDVRDVIDKAKQSGglfttkNPILFIDEIHRFSKSQQ 114
Cdd:PTZ00454 182 VLLYGPPGTGKTMLAKAVAHHTTATFIRVVGsefvqkyLGEGPRMVRDVFRLARENA------PSIIFIDEVDSIATKRF 255
|
....*.
gi 1278483409 115 DSLLGA 120
Cdd:PTZ00454 256 DAQTGA 261
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
100-222 |
3.67e-03 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 39.82 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 100 ILFIDEIHRFSKSQQDSLLGAVEKGWITLIGATTENPSFEVIPALLSRCQVYILNAFDKADL-KALLNRALKVDVELKQK 178
Cdd:PRK04132 633 IIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIaKRLRYIAENEGLELTEE 712
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1278483409 179 QInlketEALIHLSGGDARKLLNIFELVIGQNTKidITNELVLK 222
Cdd:PRK04132 713 GL-----QAILYIAEGDMRRAINILQAAAALDDK--ITDENVFL 749
|
|
| VirE |
pfam05272 |
Virulence-associated protein E; This family contains several bacterial virulence-associated ... |
42-127 |
4.88e-03 |
|
Virulence-associated protein E; This family contains several bacterial virulence-associated protein E like proteins. These proteins contain a P-loop motif.
Pssm-ID: 461607 Cd Length: 217 Bit Score: 38.31 E-value: 4.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIAntsKRPFYSLSAINSGVKDvrdviDKAKQSGGLfttknpILFIDEIHRFSKSQQDSLlgav 121
Cdd:pfam05272 54 LVLEGPQGIGKSTFFRKLA---GEDWFSDSLLDLKDKD-----AYEKLQGKW------IVELGELEAFKKSDVEAI---- 115
|
....*.
gi 1278483409 122 eKGWIT 127
Cdd:pfam05272 116 -KAFIS 120
|
|
| PspF |
COG1221 |
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ... |
40-137 |
4.97e-03 |
|
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms];
Pssm-ID: 440834 [Multi-domain] Cd Length: 835 Bit Score: 39.32 E-value: 4.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 40 PSLIFwGPPGIGKTTLAAII---ANTSKR-----PF-------YS-----LSAINSGVK---------DVRDVIDKAKqs 90
Cdd:COG1221 132 HTLIL-GPTGVGKSFFAELMyeyAIEIGVlpedaPFvvfncadYAnnpqlLMSQLFGYVkgaftgadkDKEGLIEKAD-- 208
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1278483409 91 GGlfttknpILFIDEIHRFSKSQQDSL-----------LGAVEKgWIT----LIGATTENPS 137
Cdd:COG1221 209 GG-------ILFLDEVHRLPPEGQEMLftfmdkgiyrrLGETEK-TRKanvrIIFATTEDPE 262
|
|
| RecA-like_ATAD1 |
cd19520 |
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ... |
42-116 |
7.55e-03 |
|
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410928 [Multi-domain] Cd Length: 166 Bit Score: 37.02 E-value: 7.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278483409 42 LIFWGPPGIGKTTLAAIIANTSKRPFYSLSainsgvkdVRDVIDK-----AKQSGGLFTTKNP----ILFIDEIHRFSKS 112
Cdd:cd19520 38 VLLYGPPGCGKTMLAKATAKEAGARFINLQ--------VSSLTDKwygesQKLVAAVFSLASKlqpsIIFIDEIDSFLRQ 109
|
....
gi 1278483409 113 QQDS 116
Cdd:cd19520 110 RSST 113
|
|
| |
