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Conserved domains on  [gi|1278332080|gb|PIY75418|]
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transcriptional regulator [Rhodobacterales bacterium CG_4_10_14_0_8_um_filter_70_9]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4190 COG4190
Predicted transcriptional regulator, contains HTH domain [Transcription];
6-115 4.70e-36

Predicted transcriptional regulator, contains HTH domain [Transcription];


:

Pssm-ID: 443344  Cd Length: 121  Bit Score: 119.23  E-value: 4.70e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278332080   6 NIVTLSVSARDETTARTLAAFRG-------EAQGARISFASVELLWKVLTPRRWAILRAMAGQGGLSIREIARRVGRDVK 78
Cdd:COG4190     2 KTLKIGIASLEEFRARALAAARGadagekpEPAEPVLSFESPESLARVLTPKRLELLRAIAEEGPESIRELARRLGRDVK 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1278332080  79 AVHGDVHALIEAGLLDRDATGLVAFPFV---AVRVDFTLA 115
Cdd:COG4190    82 NVHRDLKTLEELGLVELEEDGRAKRPVVpydEIEIDFPLR 121
 
Name Accession Description Interval E-value
COG4190 COG4190
Predicted transcriptional regulator, contains HTH domain [Transcription];
6-115 4.70e-36

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443344  Cd Length: 121  Bit Score: 119.23  E-value: 4.70e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278332080   6 NIVTLSVSARDETTARTLAAFRG-------EAQGARISFASVELLWKVLTPRRWAILRAMAGQGGLSIREIARRVGRDVK 78
Cdd:COG4190     2 KTLKIGIASLEEFRARALAAARGadagekpEPAEPVLSFESPESLARVLTPKRLELLRAIAEEGPESIRELARRLGRDVK 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1278332080  79 AVHGDVHALIEAGLLDRDATGLVAFPFV---AVRVDFTLA 115
Cdd:COG4190    82 NVHRDLKTLEELGLVELEEDGRAKRPVVpydEIEIDFPLR 121
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 47-95 1.42e-05

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 39.88  E-value: 1.42e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1278332080  47 LTPRRWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLLDR 95
Cdd:pfam12802   3 LTPAQFRVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVER 51
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
47-95 1.30e-04

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 37.96  E-value: 1.30e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1278332080   47 LTPRRWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLLDR 95
Cdd:smart00347   8 LTPTQFLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRR 56
 
Name Accession Description Interval E-value
COG4190 COG4190
Predicted transcriptional regulator, contains HTH domain [Transcription];
6-115 4.70e-36

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443344  Cd Length: 121  Bit Score: 119.23  E-value: 4.70e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278332080   6 NIVTLSVSARDETTARTLAAFRG-------EAQGARISFASVELLWKVLTPRRWAILRAMAGQGGLSIREIARRVGRDVK 78
Cdd:COG4190     2 KTLKIGIASLEEFRARALAAARGadagekpEPAEPVLSFESPESLARVLTPKRLELLRAIAEEGPESIRELARRLGRDVK 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1278332080  79 AVHGDVHALIEAGLLDRDATGLVAFPFV---AVRVDFTLA 115
Cdd:COG4190    82 NVHRDLKTLEELGLVELEEDGRAKRPVVpydEIEIDFPLR 121
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 47-95 1.42e-05

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 39.88  E-value: 1.42e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1278332080  47 LTPRRWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLLDR 95
Cdd:pfam12802   3 LTPAQFRVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVER 51
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
47-95 1.30e-04

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 37.96  E-value: 1.30e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1278332080   47 LTPRRWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLLDR 95
Cdd:smart00347   8 LTPTQFLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRR 56
MarR pfam01047
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 47-95 2.61e-04

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 426012 [Multi-domain]  Cd Length: 59  Bit Score: 36.37  E-value: 2.61e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1278332080  47 LTPRRWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLLDR 95
Cdd:pfam01047   1 LTLTQFHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGLIER 49
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
47-95 3.55e-04

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 37.64  E-value: 3.55e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1278332080  47 LTPRRWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLLDR 95
Cdd:COG1846    36 LTPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLVER 84
Lrp COG1522
DNA-binding transcriptional regulator, Lrp family [Transcription];
52-111 3.57e-04

DNA-binding transcriptional regulator, Lrp family [Transcription];


Pssm-ID: 441131 [Multi-domain]  Cd Length: 138  Bit Score: 37.45  E-value: 3.57e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278332080  52 WAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAG-------LLDRDATGLVAFPFVAVRVD 111
Cdd:COG1522     8 RRILRLLQEDGRLSFAELAERVGLSESTVLRRVRRLEEAGvirgygaVVDPEKLGLGVTAFVEVKVP 74
HTH_24 pfam13412
Winged helix-turn-helix DNA-binding;
51-93 8.82e-04

Winged helix-turn-helix DNA-binding;


Pssm-ID: 404317 [Multi-domain]  Cd Length: 45  Bit Score: 34.72  E-value: 8.82e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1278332080  51 RWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLL 93
Cdd:pfam13412   3 DRKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEGVI 45
HTH_ASNC smart00344
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase ...
 53-111 1.32e-03

helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli)


Pssm-ID: 214628 [Multi-domain]  Cd Length: 108  Bit Score: 35.57  E-value: 1.32e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278332080   53 AILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAG-------LLDRDATGLVAFPFVAVRVD 111
Cdd:smart00344   7 KILEELQKDARISLAELAKKVGLSPSTVHNRVKRLEEEGvikgytaVLNPKKLGLSVTAFVGVTLE 72
HTH_IclR pfam09339
IclR helix-turn-helix domain;
53-96 3.63e-03

IclR helix-turn-helix domain;


Pssm-ID: 430539 [Multi-domain]  Cd Length: 52  Bit Score: 33.15  E-value: 3.63e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1278332080  53 AILRAMAGQ-GGLSIREIARRVGRDVKAVHGDVHALIEAGLLDRD 96
Cdd:pfam09339   7 AILDALAEApGPLTLTEIARRTGLPKSTAHRLLQTLVELGYVEQD 51
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
 49-99 7.73e-03

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 32.51  E-value: 7.73e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1278332080  49 PRRWAILRAMAGQGGLSIREIARRVGRDVKAVHGDVHALIEAGLLDRDATG 99
Cdd:pfam12840  10 PTRLRILRALVGDEPLTASELARRLDISRNTLSYHLRKLEEAGLVEVVREG 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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