NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1278166495|gb|PIX36050|]
View 

MBL fold metallo-hydrolase, partial [Bacteroidetes bacterium CG_4_8_14_3_um_filter_31_14]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NorV super family cl33867
Flavorubredoxin [Energy production and conversion];
16-161 2.78e-40

Flavorubredoxin [Energy production and conversion];


The actual alignment was detected with superfamily member COG0426:

Pssm-ID: 440195 [Multi-domain]  Cd Length: 390  Bit Score: 139.58  E-value: 2.78e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  16 KNVLIAYVSAYGYTRQIAKALAEGIklENPNIDVVLADVEHITVGEIDAKLIRANGLIVGSPTLNQNIMLPVYKIFSMIN 95
Cdd:COG0426   247 KKVVIVYASMYGNTEKMAEAIAEGL--TEEGVKVKLYDLEKTDPSEIITEIFDAKGIVIGSPTYNGGAFPPIADLLGYLK 324

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278166495  96 PIREKDKPALSFGSYGWSGEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFAKVL 161
Cdd:COG0426   325 GLAPKNKLAGAFGSYGWSGEAVKLLEEKLEDAGFEVVFEPLRVKFKPTEEDLKKCEELGTDLAQKL 390
 
Name Accession Description Interval E-value
NorV COG0426
Flavorubredoxin [Energy production and conversion];
16-161 2.78e-40

Flavorubredoxin [Energy production and conversion];


Pssm-ID: 440195 [Multi-domain]  Cd Length: 390  Bit Score: 139.58  E-value: 2.78e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  16 KNVLIAYVSAYGYTRQIAKALAEGIklENPNIDVVLADVEHITVGEIDAKLIRANGLIVGSPTLNQNIMLPVYKIFSMIN 95
Cdd:COG0426   247 KKVVIVYASMYGNTEKMAEAIAEGL--TEEGVKVKLYDLEKTDPSEIITEIFDAKGIVIGSPTYNGGAFPPIADLLGYLK 324

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278166495  96 PIREKDKPALSFGSYGWSGEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFAKVL 161
Cdd:COG0426   325 GLAPKNKLAGAFGSYGWSGEAVKLLEEKLEDAGFEVVFEPLRVKFKPTEEDLKKCEELGTDLAQKL 390
PRK11921 PRK11921
anaerobic nitric oxide reductase flavorubredoxin;
18-161 4.43e-29

anaerobic nitric oxide reductase flavorubredoxin;


Pssm-ID: 237023 [Multi-domain]  Cd Length: 394  Bit Score: 110.17  E-value: 4.43e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  18 VLIAYVSAYGYTRQIAKALAEGIKLENPNIDVVLADVEHITVGEIDAKLIRANGLIVGSPTLNQNIMLPVYKIFSMINPI 97
Cdd:PRK11921  250 VTILYDTMWNSTRRMAEAIAEGIKKANKDVTVKLYNSAKSDKNDIITEVFKSKAILVGSSTINRGILSSTAAILEEIKGL 329

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278166495  98 REKDKPALSFGSYGWSGEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFAKVL 161
Cdd:PRK11921  330 GFKNKKAAAFGSYGWSGESVKIITERLKKAGFEIVNDGIRELWNPDDEALDRCRSFGENFAESL 393
flav_short TIGR01753
flavodoxin, short chain; Flavodoxins are small redox-active proteins with a flavin ...
 18-158 2.79e-14

flavodoxin, short chain; Flavodoxins are small redox-active proteins with a flavin mononucleotide (FMN) prosthetic group. They can act in nitrogen fixation by nitrogenase, in sulfite reduction, and light-dependent NADP+ reduction in during photosynthesis, among other roles. This model describes the short chain type. Many of these are involved in sulfite reduction. [Energy metabolism, Electron transport]


Pssm-ID: 273789 [Multi-domain]  Cd Length: 140  Bit Score: 65.82  E-value: 2.79e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  18 VLIAYVSAYGYTRQIAKALAEGIKlenpnidVVLADVEHITVGEIDA-KLIRANGLIVGSPT-----LNQNIMLPvykIF 91
Cdd:TIGR01753   1 ILIVYASMTGNTEEMANIIAEGLK-------EAGAEVDLLEVADADAeDLLSYDAVLLGCSTwgdedLEQDDFEP---FF 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  92 SMINPIREKDKPALSFGSYGWS---GEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFA 158
Cdd:TIGR01753  71 EELEDIDLGGKKVALFGSGDWGyefCEAVDDWEERLKEAGATIIAEGLKVDGDPEEEDLDKCREFAKDLA 140
Flavodoxin_1 pfam00258
Flavodoxin;
20-156 2.53e-09

Flavodoxin;


Pssm-ID: 425562 [Multi-domain]  Cd Length: 142  Bit Score: 52.76  E-value: 2.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  20 IAYVSAYGYTRQIAKALAEGIKLENPNIDVVLADVEHITVGEIDAKLIRANGLI---VGSPTLNqniMLPVYKIFSMINP 96
Cdd:pfam00258   1 IFYGSQTGNTEKLAEAIAEGLGEAGFEVDVVDLDDVDETLSEIEEEDLLLVVVStwgEGEPPDN---AKPFVDWLLLFGT 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278166495  97 IREKDKPALS-----FGSYGWSG--EAVKIIDASLKSLKlnvirdgiAVKFFPFGEVRNMLVEQGKE 156
Cdd:pfam00258  78 LEDGDLSGLKyavfgLGDSGYEGfcGAAKKLDEKLSELG--------ASRVGPLGEGDEDPQEDGLE 136
 
Name Accession Description Interval E-value
NorV COG0426
Flavorubredoxin [Energy production and conversion];
16-161 2.78e-40

Flavorubredoxin [Energy production and conversion];


Pssm-ID: 440195 [Multi-domain]  Cd Length: 390  Bit Score: 139.58  E-value: 2.78e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  16 KNVLIAYVSAYGYTRQIAKALAEGIklENPNIDVVLADVEHITVGEIDAKLIRANGLIVGSPTLNQNIMLPVYKIFSMIN 95
Cdd:COG0426   247 KKVVIVYASMYGNTEKMAEAIAEGL--TEEGVKVKLYDLEKTDPSEIITEIFDAKGIVIGSPTYNGGAFPPIADLLGYLK 324

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278166495  96 PIREKDKPALSFGSYGWSGEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFAKVL 161
Cdd:COG0426   325 GLAPKNKLAGAFGSYGWSGEAVKLLEEKLEDAGFEVVFEPLRVKFKPTEEDLKKCEELGTDLAQKL 390
PRK11921 PRK11921
anaerobic nitric oxide reductase flavorubredoxin;
18-161 4.43e-29

anaerobic nitric oxide reductase flavorubredoxin;


Pssm-ID: 237023 [Multi-domain]  Cd Length: 394  Bit Score: 110.17  E-value: 4.43e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  18 VLIAYVSAYGYTRQIAKALAEGIKLENPNIDVVLADVEHITVGEIDAKLIRANGLIVGSPTLNQNIMLPVYKIFSMINPI 97
Cdd:PRK11921  250 VTILYDTMWNSTRRMAEAIAEGIKKANKDVTVKLYNSAKSDKNDIITEVFKSKAILVGSSTINRGILSSTAAILEEIKGL 329

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1278166495  98 REKDKPALSFGSYGWSGEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFAKVL 161
Cdd:PRK11921  330 GFKNKKAAAFGSYGWSGESVKIITERLKKAGFEIVNDGIRELWNPDDEALDRCRSFGENFAESL 393
PRK05452 PRK05452
anaerobic nitric oxide reductase flavorubredoxin; Provisional
 20-159 1.81e-19

anaerobic nitric oxide reductase flavorubredoxin; Provisional


Pssm-ID: 235475 [Multi-domain]  Cd Length: 479  Bit Score: 84.42  E-value: 1.81e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  20 IAYVSAYGYTRQIAKALAEGIKLENPNIDVVLADVEHITVGEIDAKLIRANGLIVGSPTLNqNIMLPvyKIFSMINPI-- 97
Cdd:PRK05452  256 IFYDTMSNNTRMMADAIAQGIAEVDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGSSTMN-NVMMP--KIAGLLEEItg 332

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1278166495  98 -REKDKPALSFGSYGWSGEAVKIIDASLKSLKLNVIRdGIAVKFFPFGEVRNMLVEQGKEFAK 159
Cdd:PRK05452  333 lRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSL-SLKAKWRPDQDALELCREHGREIAR 394
flav_short TIGR01753
flavodoxin, short chain; Flavodoxins are small redox-active proteins with a flavin ...
 18-158 2.79e-14

flavodoxin, short chain; Flavodoxins are small redox-active proteins with a flavin mononucleotide (FMN) prosthetic group. They can act in nitrogen fixation by nitrogenase, in sulfite reduction, and light-dependent NADP+ reduction in during photosynthesis, among other roles. This model describes the short chain type. Many of these are involved in sulfite reduction. [Energy metabolism, Electron transport]


Pssm-ID: 273789 [Multi-domain]  Cd Length: 140  Bit Score: 65.82  E-value: 2.79e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  18 VLIAYVSAYGYTRQIAKALAEGIKlenpnidVVLADVEHITVGEIDA-KLIRANGLIVGSPT-----LNQNIMLPvykIF 91
Cdd:TIGR01753   1 ILIVYASMTGNTEEMANIIAEGLK-------EAGAEVDLLEVADADAeDLLSYDAVLLGCSTwgdedLEQDDFEP---FF 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  92 SMINPIREKDKPALSFGSYGWS---GEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFA 158
Cdd:TIGR01753  71 EELEDIDLGGKKVALFGSGDWGyefCEAVDDWEERLKEAGATIIAEGLKVDGDPEEEDLDKCREFAKDLA 140
PRK05568 PRK05568
flavodoxin; Provisional
 16-163 5.61e-12

flavodoxin; Provisional


Pssm-ID: 235508 [Multi-domain]  Cd Length: 142  Bit Score: 59.82  E-value: 5.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  16 KNVLIAYVSAYGYTRQIAKALAEGIKLENpnidvvlADVEHITVGEIDAKLIR-ANGLIVGSP-----TLNQNIMLP-VY 88
Cdd:PRK05568    2 KKINIIYWSGTGNTEAMANLIAEGAKENG-------AEVKLLNVSEASVDDVKgADVVALGSPamgdeVLEEGEMEPfVE 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1278166495  89 KIFSMInpireKDKPALSFGSYGW-SGEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVrnmlVEQGKEFAKVLMK 163
Cdd:PRK05568   75 SISSLV-----KGKKLVLFGSYGWgDGEWMRDWVERMEGYGANLVNEGLIVNNTPEGEG----IEKCKALGEALAK 141
FldA COG0716
Flavodoxin [Energy production and conversion]; Flavodoxin is part of the Pathway/BioSystem: ...
 18-132 1.15e-09

Flavodoxin [Energy production and conversion]; Flavodoxin is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440480 [Multi-domain]  Cd Length: 135  Bit Score: 53.75  E-value: 1.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  18 VLIAYVSAYGYTRQIAKALAEgiKLENPNIDVVlaDVEHITVGEIDAklirANGLIVGSPTLNQNIMLPVYKIFSMINPi 97
Cdd:COG0716     1 ILIVYGSTTGNTEKVAEAIAE--ALGAAGVDLF--EIEDADLDDLED----YDLLILGTPTWAGELPDDWEDFLEELKE- 71

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1278166495  98 REKDKPALSFGSYGWS--GEAVKIIDASLKSLKLNVI 132
Cdd:COG0716    72 DLSGKKVALFGTGDSSgyGDALGELKELLEEKGAKVV 108
Flavodoxin_1 pfam00258
Flavodoxin;
20-156 2.53e-09

Flavodoxin;


Pssm-ID: 425562 [Multi-domain]  Cd Length: 142  Bit Score: 52.76  E-value: 2.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  20 IAYVSAYGYTRQIAKALAEGIKLENPNIDVVLADVEHITVGEIDAKLIRANGLI---VGSPTLNqniMLPVYKIFSMINP 96
Cdd:pfam00258   1 IFYGSQTGNTEKLAEAIAEGLGEAGFEVDVVDLDDVDETLSEIEEEDLLLVVVStwgEGEPPDN---AKPFVDWLLLFGT 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278166495  97 IREKDKPALS-----FGSYGWSG--EAVKIIDASLKSLKlnvirdgiAVKFFPFGEVRNMLVEQGKE 156
Cdd:pfam00258  78 LEDGDLSGLKyavfgLGDSGYEGfcGAAKKLDEKLSELG--------ASRVGPLGEGDEDPQEDGLE 136
PRK05569 PRK05569
flavodoxin; Provisional
 16-159 2.28e-07

flavodoxin; Provisional


Pssm-ID: 135442 [Multi-domain]  Cd Length: 141  Bit Score: 47.52  E-value: 2.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  16 KNVLIAYVSAYGYTRQIAKALAEGikLENPNIDVVLADVEHITVGEIdaklIRANGLIVGSPTLNQNI-----MLPVYKI 90
Cdd:PRK05569    2 KKVSIIYWSCGGNVEVLANTIADG--AKEAGAEVTIKHVADAKVEDV----LEADAVAFGSPSMDNNNieqeeMAPFLDQ 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  91 FSMINPIrekDKPALSFGSYGW-SGEAVKIIDASLKSLKLNVIRDgIAVKFFPFGEVRNMLVEQGKEFAK 159
Cdd:PRK05569   76 FKLTPNE---NKKCILFGSYGWdNGEFMKLWKDRMKDYGFNVIGD-LAVNESPNKEELNSAKELGKKLAK 141
PRK06756 PRK06756
flavodoxin; Provisional
 18-161 1.43e-03

flavodoxin; Provisional


Pssm-ID: 168663 [Multi-domain]  Cd Length: 148  Bit Score: 37.17  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  18 VLIAYVSAYGYTRQIAKALAEGIKLENPNIDVVlaDVehitVGEIDAKLIRA-NGLIVGSPTLNQNiMLP--VYKIFSMI 94
Cdd:PRK06756    4 LVMIFASMSGNTEEMADHIAGVIRETENEIEVI--DI----MDSPEASILEQyDGIILGAYTWGDG-DLPddFLDFYDAM 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1278166495  95 NPIREKDKPALSFGS----YGWSGEAVKIIDASLKSLKLNVIRDGIAVKFFPFGEVRNMLVEQGKEFAKVL 161
Cdd:PRK06756   77 DSIDLTGKKAAVFGScdsaYPKYGVAVDILIEKLQERGAAVVLEGLKVELTPEDEDVEKCLQFGAEFVKHL 147
WrbA COG0655
Multimeric flavodoxin WrbA, includes NAD(P)H:quinone oxidoreductase [Energy production and ...
 17-78 1.50e-03

Multimeric flavodoxin WrbA, includes NAD(P)H:quinone oxidoreductase [Energy production and conversion];


Pssm-ID: 440420 [Multi-domain]  Cd Length: 181  Bit Score: 37.60  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  17 NVLIAY--VSAYGYTRQIAKALAEGIKLENpnidvvlADVEHITVGEID-----------------------AKLIRANG 71
Cdd:COG0655     1 KILVINgsPRKNGNTAALAEAVAEGAEEAG-------AEVELIRLADLDikpcigcggtgkcvikddmnaiyEKLLEADG 73


                  ....*..
gi 1278166495  72 LIVGSPT 78
Cdd:COG0655    74 IIFGSPT 80
Flavodoxin_5 pfam12724
Flavodoxin domain; This is a family of flavodoxins. Flavodoxins are electron transfer proteins ...
 19-78 4.33e-03

Flavodoxin domain; This is a family of flavodoxins. Flavodoxins are electron transfer proteins that carry a molecule of non-covalently bound FMN.


Pssm-ID: 463681 [Multi-domain]  Cd Length: 144  Bit Score: 35.70  E-value: 4.33e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1278166495  19 LIAYVSAYGYTRQIAKALAEGIKLEnpnidVVLADVEHITVGEidaKLIRANGLIVGSPT 78
Cdd:pfam12724   1 LILYSSRDGQTKKIAERIAEELREE-----GELVDVEDVEAGE---DLSSYDAVVIGASI 52
PRK03767 PRK03767
NAD(P)H:quinone oxidoreductase; Provisional
 18-78 7.08e-03

NAD(P)H:quinone oxidoreductase; Provisional


Pssm-ID: 179647  Cd Length: 200  Bit Score: 35.67  E-value: 7.08e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1278166495  18 VLIAYVSAYGYTRQIAKALAEGIKlENPNIDVVL--------ADVEHITVGEID--------AKLIRANGLIVGSPT 78
Cdd:PRK03767    4 VLVLYYSMYGHIETMAEAVAEGAR-EVAGAEVTIkrvpetvpEEVAKKAGGKTDqaapvatpDELADYDAIIFGTPT 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH