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Conserved domains on  [gi|1276668727|gb|ATV30287|]
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hypothetical protein CTM46_01725 [Prevotella intermedia]

Protein Classification

CIA30 family protein( domain architecture ID 232043)

CIA30 family protein similar to eukaryotic complex I intermediate-associated protein 30, a chaperone protein involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I)

Gene Ontology:  GO:0032981|GO:0006120|GO:0051082

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CIA30 super family cl21728
Complex I intermediate-associated protein 30 (CIA30); This protein is associated with ...
 6-44 5.60e-03

Complex I intermediate-associated protein 30 (CIA30); This protein is associated with mitochondrial Complex I intermediate-associated protein 30 (CIA30) in human and mouse. The family is also present in Schizosaccharomyces pombe which does not contain the NADH dehydrogenase component of complex I, or many of the other essential subunits. This means it is possible that this family of protein may not be directly involved in oxidative phosphorylation.


The actual alignment was detected with superfamily member pfam08547:

Pssm-ID: 473944  Cd Length: 156  Bit Score: 32.56  E-value: 5.60e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1276668727   6 NLLFCVPKAAVLHG-----KSVGFASQKSRFRNVKAQLSLFNGI 44
Cdd:pfam08547  27 SLKLSVDGTARFSGnlsleNNGGFASVRSRNFDPPLDLSGYDGL 70
 
Name Accession Description Interval E-value
CIA30 pfam08547
Complex I intermediate-associated protein 30 (CIA30); This protein is associated with ...
 6-44 5.60e-03

Complex I intermediate-associated protein 30 (CIA30); This protein is associated with mitochondrial Complex I intermediate-associated protein 30 (CIA30) in human and mouse. The family is also present in Schizosaccharomyces pombe which does not contain the NADH dehydrogenase component of complex I, or many of the other essential subunits. This means it is possible that this family of protein may not be directly involved in oxidative phosphorylation.


Pssm-ID: 462515  Cd Length: 156  Bit Score: 32.56  E-value: 5.60e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1276668727   6 NLLFCVPKAAVLHG-----KSVGFASQKSRFRNVKAQLSLFNGI 44
Cdd:pfam08547  27 SLKLSVDGTARFSGnlsleNNGGFASVRSRNFDPPLDLSGYDGL 70
 
Name Accession Description Interval E-value
CIA30 pfam08547
Complex I intermediate-associated protein 30 (CIA30); This protein is associated with ...
 6-44 5.60e-03

Complex I intermediate-associated protein 30 (CIA30); This protein is associated with mitochondrial Complex I intermediate-associated protein 30 (CIA30) in human and mouse. The family is also present in Schizosaccharomyces pombe which does not contain the NADH dehydrogenase component of complex I, or many of the other essential subunits. This means it is possible that this family of protein may not be directly involved in oxidative phosphorylation.


Pssm-ID: 462515  Cd Length: 156  Bit Score: 32.56  E-value: 5.60e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1276668727   6 NLLFCVPKAAVLHG-----KSVGFASQKSRFRNVKAQLSLFNGI 44
Cdd:pfam08547  27 SLKLSVDGTARFSGnlsleNNGGFASVRSRNFDPPLDLSGYDGL 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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