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Conserved domains on  [gi|1274921619|gb|ATS07586|]
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SPOR domain-containing protein [Porphyromonas gingivalis]

Protein Classification

SPOR domain-containing protein( domain architecture ID 11459733)

SPOR domain-containing protein similar to Bacillus subtilis stage II sporulation protein B and Escherichia coli cell division proteins FtsN, DamX, and DedD

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 48-142 6.96e-09

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 51.31  E-value: 6.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1274921619  48 ETRPIVSKPATNVQIRQEKLSAysgedASRLDRFSVVVGSFRNATNARSLKERLESEGYTPILAE---NEQGMLRVIVAS 124
Cdd:COG3147    38 AAKPAAPKPAAAAAAAPAAKAA-----APAGGGWVVQLGAFSNEDNAKELVAKLRAAGYPAYTEPvttGGGTLYRVRVGP 112

                          90
                  ....*....|....*...
gi 1274921619 125 FPSREEAIAAREAVKERY 142
Cdd:COG3147   113 FASRAEAEAALAKLKKLT 130
 
Name Accession Description Interval E-value
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 48-142 6.96e-09

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 51.31  E-value: 6.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1274921619  48 ETRPIVSKPATNVQIRQEKLSAysgedASRLDRFSVVVGSFRNATNARSLKERLESEGYTPILAE---NEQGMLRVIVAS 124
Cdd:COG3147    38 AAKPAAPKPAAAAAAAPAAKAA-----APAGGGWVVQLGAFSNEDNAKELVAKLRAAGYPAYTEPvttGGGTLYRVRVGP 112

                          90
                  ....*....|....*...
gi 1274921619 125 FPSREEAIAAREAVKERY 142
Cdd:COG3147   113 FASRAEAEAALAKLKKLT 130
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 80-145 3.20e-08

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 48.12  E-value: 3.20e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1274921619  80 RFSVVVGSFRNATNARSLKERLESEGYTPILA--ENEQGMLRVIVASFPSREEAIAAREAVKERYAPN 145
Cdd:pfam05036   4 GYYVQLGAFSNEANAEALAAKLRAKGFAAYVAvtSKGGGLYRVRVGPFASREEARAALKKLKALAGLS 71
 
Name Accession Description Interval E-value
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 48-142 6.96e-09

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 51.31  E-value: 6.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1274921619  48 ETRPIVSKPATNVQIRQEKLSAysgedASRLDRFSVVVGSFRNATNARSLKERLESEGYTPILAE---NEQGMLRVIVAS 124
Cdd:COG3147    38 AAKPAAPKPAAAAAAAPAAKAA-----APAGGGWVVQLGAFSNEDNAKELVAKLRAAGYPAYTEPvttGGGTLYRVRVGP 112

                          90
                  ....*....|....*...
gi 1274921619 125 FPSREEAIAAREAVKERY 142
Cdd:COG3147   113 FASRAEAEAALAKLKKLT 130
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 80-145 3.20e-08

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 48.12  E-value: 3.20e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1274921619  80 RFSVVVGSFRNATNARSLKERLESEGYTPILA--ENEQGMLRVIVASFPSREEAIAAREAVKERYAPN 145
Cdd:pfam05036   4 GYYVQLGAFSNEANAEALAAKLRAKGFAAYVAvtSKGGGLYRVRVGPFASREEARAALKKLKALAGLS 71
FtsN COG3087
Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];
21-140 3.95e-08

Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442321 [Multi-domain]  Cd Length: 198  Bit Score: 50.39  E-value: 3.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1274921619  21 KSKQSAYRQAYEQAKEREIAQAEDKDMETRPIVSKPATNVQIRQEKLSAYSGEDASrldrFSVVVGSFRNATNARSLKER 100
Cdd:COG3087    69 AAAALAALNAAAAALAAASAAAAAAAAPAAAAAEAAAAPAGMAKKEAAAAPAAKKP----YYVQVGAFRSRANAERLRAR 144

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1274921619 101 LESEGYTPILAENE---QGMLRVIVASFPSREEAIAAREAVKE 140
Cdd:COG3087   145 LALLGLEARVVEVEvggGTWYRVRVGPFSSRAEAEKAREKLKA 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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