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Conserved domains on  [gi|127295|sp|P08169|]
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RecName: Full=Cation-independent mannose-6-phosphate receptor; Short=CI Man-6-P receptor; Short=CI-MPR; Short=M6PR; AltName: Full=300 kDa mannose 6-phosphate receptor; Short=MPR 300; AltName: Full=Insulin-like growth factor 2 receptor; AltName: Full=Insulin-like growth factor II receptor; Short=IGF-II receptor; AltName: CD_antigen=CD222; Flags: Precursor

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1040-1187 7.58e-69

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 228.15  E-value: 7.58e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1040 GRADAFIIRFVCNDDVYPGTPKFLHQDIdsslGIRDTFFEFETALACV-PSPVDCQVTDPAGNEYDLSGLSKARKPWTAV 1118
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 127295     1119 DTFDEGKKRTFYLSVCTPLPYIPGCHgTAVGCCLVTEDSKLNLGVVQISPQVgANGSLSLVYVNGDKCK 1187
Cdd:pfam00878   77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQK-TNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1331-1471 7.21e-66

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 219.67  E-value: 7.21e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1331 VYQRSTTIFFYCDRST--QAPVFLQETS-DCSYLFEWRTQYACPPYDLTECSFKNEAGETYDLSSLSRYSDNWEAVTGTG 1407
Cdd:pfam00878    1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295     1408 S--TEHYLINVCKslsPQAGSDPCPPEAAVCLLGGPKPVNLGRVRDSPQWSQGLTLLKYVDGDLCP 1471
Cdd:pfam00878   81 DgkKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
432-582 4.28e-56

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 191.94  E-value: 4.28e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      432 GFQRMSVINFECNQTAGNngrGAPVFTGEV--DCTYFFTWDTKYACVhEKEALLCGVSDGK-QRFDLSALARHSEleqNW 508
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYN---GAPVFLHEDigDCSYFFEWETAYACV-KPEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 127295      509 EAVDGSQrEAEKKHFFINICHrvlQTGQARGCPEDAAVCAVDKNGSKNLGRFISSPTREKGNIQLSYSDGDECG 582
Cdd:pfam00878   74 EAVDTSG-DGKKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
584-724 1.97e-41

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 149.95  E-value: 1.97e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      584 GQKIITNITLMCKPGDLESAPVLTTSRADGCFYEFEWRTAAACVLsrTEGDNCTVFDSqAGFSFDLTPLTKK-DAYKVET 662
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACVK--PEDVDCQVTDA-AGNEYDLSSLSRYsKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 127295      663 DKYE-----FHINVCGP-VSVGACPPDSGACQVSRSdrKSWNLGRSNAKLSYYDGMIQLTYRDGTPYN 724
Cdd:pfam00878   78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDKG--KSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
731-883 1.46e-27

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 110.28  E-value: 1.46e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      731 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECIVTDPVTlDQYDLSRLAKSEGgpggNWYSLDN 807
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295      808 GGARSTwRKYYINVCRPLNPVPGCDRYASACQMkyqGEQGSYsetvsisNLGVAKTGPMVEDsGSLLLEYVNGSAC 883
Cdd:pfam00878   79 SGDGKK-RHFYINVCHPLPGIPGCPSAAGVCLV---DKGKSW-------NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
FN2 smart00059
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ...
1906-1951 4.07e-19

Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function.


:

Pssm-ID: 128373  Cd Length: 49  Bit Score: 82.73  E-value: 4.07e-19
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 127295      1906 TEDGEPCVFPFVFNGKSYEECVVESRAR--LWCATTANYDRDHEWGFC 1951
Cdd:smart00059    2 NSDGEPCVFPFIYNGKKYHDCTSEGRSDgmLWCSTTPNYDRDGKWGFC 49
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1475-1608 3.49e-18

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 83.31  E-value: 3.49e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1475 RKKSTTIRFTCSESHVNSRPMFISAV-EDCEYTFSWPTAAACAVKSNVhdDCQVTNPAtGHLFDLSSLSGRAG-----FT 1548
Cdd:pfam00878    2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweavDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 127295     1549 AAYSEKGLVYLSVCGDN---ENCANGVGACF--GQTRISVGKASKRLTYVDQVLQLVYEGGSPCP 1608
Cdd:pfam00878   79 SGDGKKRHFYINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
131-271 5.04e-16

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 77.15  E-value: 5.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      131 KIQSSITFLCGKTL--GTPEFVTAT--DCVHYFEWRTTAACKKnifkaNKEVPCYAFDRELKKHDLNPLIKTSGAYLVDD 206
Cdd:pfam00878    3 QRATIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 127295      207 SDPDTS---LFINVCRdievlraSSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKlVSNDRLVLSYV 271
Cdd:pfam00878   78 TSGDGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYV 137
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1768-1903 5.50e-16

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 77.15  E-value: 5.50e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1768 TSLITFHCKRGVSMGTPKLLR--TSVCDFVFEWETPLVCPDEVKTDgCSLTDEQlYYSFNLSSLSKS-------TFKVTR 1838
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYACVKPEDVD-CQVTDAA-GNEYDLSSLSRYsknweavDTSGDG 82
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295     1839 GPHTYSVGVCTAAAGLDegGCK-DGAVCLLSGSKGASFGRLaSMKLDYrhQDEAVILSYANGDTCP 1903
Cdd:pfam00878   83 KKRHFYINVCHPLPGIP--GCPsAAGVCLVDKGKSWNLGVV-QSSPQK--TNGSIQLSYVNGDLCG 143
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1617-1740 1.08e-15

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 76.38  E-value: 1.08e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1617 SVISFVCRPEVGPtNRPMLISLDKRTCTLFFSWHTPLACEQT--TECSVRNGSSL-IDLSPLIHRTGGYEAYDESEDDGS 1693
Cdd:pfam00878    6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACVKPedVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 127295     1694 DTspdFYINICQPLNPMHGlaCPAGTAVCKVPVDGpPIDIGRVAGPP 1740
Cdd:pfam00878   85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1958-2092 2.35e-12

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 66.75  E-value: 2.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1958 RTSVIIFKCDEDADVGRPQVFSEVRG-CEVTFEWKTKVVCPPKK-MECKFV-QKHRTYDLRLLSSLTGSWSFVHNGAS-- 2032
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVDTSGDgk 83
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 127295     2033 ---YYINLCQKIYKGPqDCSERASVCKKSTSGEVQvLGLVHTqKLDVVDDRVIVTYSKGHYCG 2092
Cdd:pfam00878   84 krhFYINVCHPLPGIP-GCPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
ATG27 super family cl39051
Autophagy-related protein 27;
1262-1374 2.55e-07

Autophagy-related protein 27;


The actual alignment was detected with superfamily member pfam02157:

Pssm-ID: 476860  Cd Length: 254  Bit Score: 54.40  E-value: 2.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1262 GEYTYYFRVCGEltsgVCPTSDKSKVIsscQEKRGPQGfQKVAGLFNQklTYE-NGV--LKMNYTGGDT----CHKvYQR 1334
Cdd:pfam02157   46 ETYTYNFRVCRE----VGKTASDAGLV---QIDKKNGK-ETVIGRINE--TQVfNGSdwIMLIYKGGDEygshCGK-EKR 114
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 127295     1335 STTIFFYCDRSTQAPVFL------QETSDCSYLFEWRTQYACPPYD 1374
Cdd:pfam02157  115 KAIIMISCNRKVLADNFTivieerEKEQDCFYLFELDSSLACPPED 160
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2250-2309 6.44e-06

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 48.26  E-value: 6.44e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 127295     2250 SSTIFFHCDPLVKDGIPEFSHET-ADCQYLFSWHTSAVCPLGAGFDEEIAgDDAQEHKGLS 2309
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDVDCQVT-DAAGNEYDLS 64
ATG27 super family cl39051
Autophagy-related protein 27;
330-485 1.55e-05

Autophagy-related protein 27;


The actual alignment was detected with superfamily member pfam02157:

Pssm-ID: 476860  Cd Length: 254  Bit Score: 49.01  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      330 ESRSCSL-SSAQHDVAVDLQPLSRVEASDSLFY----TSEADEYTYYLSICG--GSQAPicnkkDAAVCQVKKADSTQVk 402
Cdd:pfam02157    5 EEKKCDLvGEESSESQKERALLKRLEPLANKSFevtvGSGPETYTYNFRVCRevGKTAS-----DAGLVQIDKKNGKET- 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      403 VAGRPQNLTLRYSDGDLTLIYFGGEECSS---GFQRMSVINFECNQ--TAGNngrgapvFT-------GEVDCTYFFTWD 470
Cdd:pfam02157   79 VIGRINETQVFNGSDWIMLIYKGGDEYGShcgKEKRKAIIMISCNRkvLADN-------FTivieereKEQDCFYLFELD 151
                          170
                   ....*....|....*
gi 127295      471 TKYACVHEKEALLCG 485
Cdd:pfam02157  152 SSLACPPEDSHLSVG 166
ATG27 super family cl39051
Autophagy-related protein 27;
2173-2288 1.24e-03

Autophagy-related protein 27;


The actual alignment was detected with superfamily member pfam02157:

Pssm-ID: 476860  Cd Length: 254  Bit Score: 43.23  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2173 VRTNGDRYIYEIQLSSITGSSSPacsGASICQRKANDQHfSRKVGTSNQTryYVQDGDLDVVFT------SSSKCGKDKT 2246
Cdd:pfam02157   41 VGSGPETYTYNFRVCREVGKTAS---DAGLVQIDKKNGK-ETVIGRINET--QVFNGSDWIMLIykggdeYGSHCGKEKR 114
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 127295     2247 KSVsstIFFHCDPLVKDG----IPEFSHETADCQYLFSWHTSAVCP 2288
Cdd:pfam02157  115 KAI---IMISCNRKVLADnftiVIEEREKEQDCFYLFELDSSLACP 157
CIMR super family cl39052
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2098-2242 3.79e-03

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


The actual alignment was detected with superfamily member pfam00878:

Pssm-ID: 425923  Cd Length: 143  Bit Score: 40.17  E-value: 3.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2098 SAVIELTCAKTV--GRPSFTRFDVDSCTYHFSWDSRAACaVKPqevQMVNGTITNPAnGRSFSLGDI--YFKRFSAsgdV 2173
Cdd:pfam00878    5 ATIIRFVCNDTAynGAPVFLHEDIGDCSYFFEWETAYAC-VKP---EDVDCQVTDAA-GNEYDLSSLsrYSKNWEA---V 76
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 127295     2174 RTNGD--RYIYEIQLSSITGSSSPACSGASICQRKANDqhfSRKVGTSNQTRYYVqDGDLDVVFTSSSKCG 2242
Cdd:pfam00878   77 DTSGDgkKRHFYINVCHPLPGIPGCPSAAGVCLVDKGK---SWNLGVVQSSPQKT-NGSIQLSYVNGDLCG 143
 
Name Accession Description Interval E-value
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1040-1187 7.58e-69

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 228.15  E-value: 7.58e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1040 GRADAFIIRFVCNDDVYPGTPKFLHQDIdsslGIRDTFFEFETALACV-PSPVDCQVTDPAGNEYDLSGLSKARKPWTAV 1118
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 127295     1119 DTFDEGKKRTFYLSVCTPLPYIPGCHgTAVGCCLVTEDSKLNLGVVQISPQVgANGSLSLVYVNGDKCK 1187
Cdd:pfam00878   77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQK-TNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1331-1471 7.21e-66

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 219.67  E-value: 7.21e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1331 VYQRSTTIFFYCDRST--QAPVFLQETS-DCSYLFEWRTQYACPPYDLTECSFKNEAGETYDLSSLSRYSDNWEAVTGTG 1407
Cdd:pfam00878    1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295     1408 S--TEHYLINVCKslsPQAGSDPCPPEAAVCLLGGPKPVNLGRVRDSPQWSQGLTLLKYVDGDLCP 1471
Cdd:pfam00878   81 DgkKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
432-582 4.28e-56

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 191.94  E-value: 4.28e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      432 GFQRMSVINFECNQTAGNngrGAPVFTGEV--DCTYFFTWDTKYACVhEKEALLCGVSDGK-QRFDLSALARHSEleqNW 508
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYN---GAPVFLHEDigDCSYFFEWETAYACV-KPEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 127295      509 EAVDGSQrEAEKKHFFINICHrvlQTGQARGCPEDAAVCAVDKNGSKNLGRFISSPTREKGNIQLSYSDGDECG 582
Cdd:pfam00878   74 EAVDTSG-DGKKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
584-724 1.97e-41

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 149.95  E-value: 1.97e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      584 GQKIITNITLMCKPGDLESAPVLTTSRADGCFYEFEWRTAAACVLsrTEGDNCTVFDSqAGFSFDLTPLTKK-DAYKVET 662
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACVK--PEDVDCQVTDA-AGNEYDLSSLSRYsKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 127295      663 DKYE-----FHINVCGP-VSVGACPPDSGACQVSRSdrKSWNLGRSNAKLSYYDGMIQLTYRDGTPYN 724
Cdd:pfam00878   78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDKG--KSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
731-883 1.46e-27

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 110.28  E-value: 1.46e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      731 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECIVTDPVTlDQYDLSRLAKSEGgpggNWYSLDN 807
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295      808 GGARSTwRKYYINVCRPLNPVPGCDRYASACQMkyqGEQGSYsetvsisNLGVAKTGPMVEDsGSLLLEYVNGSAC 883
Cdd:pfam00878   79 SGDGKK-RHFYINVCHPLPGIPGCPSAAGVCLV---DKGKSW-------NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
FN2 smart00059
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ...
1906-1951 4.07e-19

Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function.


Pssm-ID: 128373  Cd Length: 49  Bit Score: 82.73  E-value: 4.07e-19
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 127295      1906 TEDGEPCVFPFVFNGKSYEECVVESRAR--LWCATTANYDRDHEWGFC 1951
Cdd:smart00059    2 NSDGEPCVFPFIYNGKKYHDCTSEGRSDgmLWCSTTPNYDRDGKWGFC 49
FN2 cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ...
1906-1951 9.13e-19

Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.


Pssm-ID: 238019  Cd Length: 48  Bit Score: 81.58  E-value: 9.13e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 127295   1906 TEDGEPCVFPFVFNGKSYEECVVESRA--RLWCATTANYDRDHEWGFC 1951
Cdd:cd00062    1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1475-1608 3.49e-18

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 83.31  E-value: 3.49e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1475 RKKSTTIRFTCSESHVNSRPMFISAV-EDCEYTFSWPTAAACAVKSNVhdDCQVTNPAtGHLFDLSSLSGRAG-----FT 1548
Cdd:pfam00878    2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweavDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 127295     1549 AAYSEKGLVYLSVCGDN---ENCANGVGACF--GQTRISVGKASKRLTYVDQVLQLVYEGGSPCP 1608
Cdd:pfam00878   79 SGDGKKRHFYINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
131-271 5.04e-16

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 77.15  E-value: 5.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      131 KIQSSITFLCGKTL--GTPEFVTAT--DCVHYFEWRTTAACKKnifkaNKEVPCYAFDRELKKHDLNPLIKTSGAYLVDD 206
Cdd:pfam00878    3 QRATIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 127295      207 SDPDTS---LFINVCRdievlraSSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKlVSNDRLVLSYV 271
Cdd:pfam00878   78 TSGDGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYV 137
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1768-1903 5.50e-16

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 77.15  E-value: 5.50e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1768 TSLITFHCKRGVSMGTPKLLR--TSVCDFVFEWETPLVCPDEVKTDgCSLTDEQlYYSFNLSSLSKS-------TFKVTR 1838
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYACVKPEDVD-CQVTDAA-GNEYDLSSLSRYsknweavDTSGDG 82
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295     1839 GPHTYSVGVCTAAAGLDegGCK-DGAVCLLSGSKGASFGRLaSMKLDYrhQDEAVILSYANGDTCP 1903
Cdd:pfam00878   83 KKRHFYINVCHPLPGIP--GCPsAAGVCLVDKGKSWNLGVV-QSSPQK--TNGSIQLSYVNGDLCG 143
fn2 pfam00040
Fibronectin type II domain;
1912-1951 9.01e-16

Fibronectin type II domain;


Pssm-ID: 459645  Cd Length: 42  Bit Score: 72.99  E-value: 9.01e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 127295     1912 CVFPFVFNGKSYEECVVESRA--RLWCATTANYDRDHEWGFC 1951
Cdd:pfam00040    1 CVFPFKYKGKWYHTCTTDGRRsgRLWCATTANYDGDGKWGYC 42
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1617-1740 1.08e-15

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 76.38  E-value: 1.08e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1617 SVISFVCRPEVGPtNRPMLISLDKRTCTLFFSWHTPLACEQT--TECSVRNGSSL-IDLSPLIHRTGGYEAYDESEDDGS 1693
Cdd:pfam00878    6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACVKPedVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 127295     1694 DTspdFYINICQPLNPMHGlaCPAGTAVCKVPVDGpPIDIGRVAGPP 1740
Cdd:pfam00878   85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1958-2092 2.35e-12

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 66.75  E-value: 2.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1958 RTSVIIFKCDEDADVGRPQVFSEVRG-CEVTFEWKTKVVCPPKK-MECKFV-QKHRTYDLRLLSSLTGSWSFVHNGAS-- 2032
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVDTSGDgk 83
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 127295     2033 ---YYINLCQKIYKGPqDCSERASVCKKSTSGEVQvLGLVHTqKLDVVDDRVIVTYSKGHYCG 2092
Cdd:pfam00878   84 krhFYINVCHPLPGIP-GCPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
1262-1374 2.55e-07

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 54.40  E-value: 2.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1262 GEYTYYFRVCGEltsgVCPTSDKSKVIsscQEKRGPQGfQKVAGLFNQklTYE-NGV--LKMNYTGGDT----CHKvYQR 1334
Cdd:pfam02157   46 ETYTYNFRVCRE----VGKTASDAGLV---QIDKKNGK-ETVIGRINE--TQVfNGSdwIMLIYKGGDEygshCGK-EKR 114
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 127295     1335 STTIFFYCDRSTQAPVFL------QETSDCSYLFEWRTQYACPPYD 1374
Cdd:pfam02157  115 KAIIMISCNRKVLADNFTivieerEKEQDCFYLFELDSSLACPPED 160
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2250-2309 6.44e-06

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 48.26  E-value: 6.44e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 127295     2250 SSTIFFHCDPLVKDGIPEFSHET-ADCQYLFSWHTSAVCPLGAGFDEEIAgDDAQEHKGLS 2309
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDVDCQVT-DAAGNEYDLS 64
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
330-485 1.55e-05

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 49.01  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      330 ESRSCSL-SSAQHDVAVDLQPLSRVEASDSLFY----TSEADEYTYYLSICG--GSQAPicnkkDAAVCQVKKADSTQVk 402
Cdd:pfam02157    5 EEKKCDLvGEESSESQKERALLKRLEPLANKSFevtvGSGPETYTYNFRVCRevGKTAS-----DAGLVQIDKKNGKET- 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      403 VAGRPQNLTLRYSDGDLTLIYFGGEECSS---GFQRMSVINFECNQ--TAGNngrgapvFT-------GEVDCTYFFTWD 470
Cdd:pfam02157   79 VIGRINETQVFNGSDWIMLIYKGGDEYGShcgKEKRKAIIMISCNRkvLADN-------FTivieereKEQDCFYLFELD 151
                          170
                   ....*....|....*
gi 127295      471 TKYACVHEKEALLCG 485
Cdd:pfam02157  152 SSLACPPEDSHLSVG 166
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
2173-2288 1.24e-03

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 43.23  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2173 VRTNGDRYIYEIQLSSITGSSSPacsGASICQRKANDQHfSRKVGTSNQTryYVQDGDLDVVFT------SSSKCGKDKT 2246
Cdd:pfam02157   41 VGSGPETYTYNFRVCREVGKTAS---DAGLVQIDKKNGK-ETVIGRINET--QVFNGSDWIMLIykggdeYGSHCGKEKR 114
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 127295     2247 KSVsstIFFHCDPLVKDG----IPEFSHETADCQYLFSWHTSAVCP 2288
Cdd:pfam02157  115 KAI---IMISCNRKVLADnftiVIEEREKEQDCFYLFELDSSLACP 157
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2098-2242 3.79e-03

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 40.17  E-value: 3.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2098 SAVIELTCAKTV--GRPSFTRFDVDSCTYHFSWDSRAACaVKPqevQMVNGTITNPAnGRSFSLGDI--YFKRFSAsgdV 2173
Cdd:pfam00878    5 ATIIRFVCNDTAynGAPVFLHEDIGDCSYFFEWETAYAC-VKP---EDVDCQVTDAA-GNEYDLSSLsrYSKNWEA---V 76
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 127295     2174 RTNGD--RYIYEIQLSSITGSSSPACSGASICQRKANDqhfSRKVGTSNQTRYYVqDGDLDVVFTSSSKCG 2242
Cdd:pfam00878   77 DTSGDgkKRHFYINVCHPLPGIPGCPSAAGVCLVDKGK---SWNLGVVQSSPQKT-NGSIQLSYVNGDLCG 143
 
Name Accession Description Interval E-value
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1040-1187 7.58e-69

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 228.15  E-value: 7.58e-69
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1040 GRADAFIIRFVCNDDVYPGTPKFLHQDIdsslGIRDTFFEFETALACV-PSPVDCQVTDPAGNEYDLSGLSKARKPWTAV 1118
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 127295     1119 DTFDEGKKRTFYLSVCTPLPYIPGCHgTAVGCCLVTEDSKLNLGVVQISPQVgANGSLSLVYVNGDKCK 1187
Cdd:pfam00878   77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQK-TNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1331-1471 7.21e-66

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 219.67  E-value: 7.21e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1331 VYQRSTTIFFYCDRST--QAPVFLQETS-DCSYLFEWRTQYACPPYDLTECSFKNEAGETYDLSSLSRYSDNWEAVTGTG 1407
Cdd:pfam00878    1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295     1408 S--TEHYLINVCKslsPQAGSDPCPPEAAVCLLGGPKPVNLGRVRDSPQWSQGLTLLKYVDGDLCP 1471
Cdd:pfam00878   81 DgkKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
432-582 4.28e-56

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 191.94  E-value: 4.28e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      432 GFQRMSVINFECNQTAGNngrGAPVFTGEV--DCTYFFTWDTKYACVhEKEALLCGVSDGK-QRFDLSALARHSEleqNW 508
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYN---GAPVFLHEDigDCSYFFEWETAYACV-KPEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 127295      509 EAVDGSQrEAEKKHFFINICHrvlQTGQARGCPEDAAVCAVDKNGSKNLGRFISSPTREKGNIQLSYSDGDECG 582
Cdd:pfam00878   74 EAVDTSG-DGKKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
584-724 1.97e-41

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 149.95  E-value: 1.97e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      584 GQKIITNITLMCKPGDLESAPVLTTSRADGCFYEFEWRTAAACVLsrTEGDNCTVFDSqAGFSFDLTPLTKK-DAYKVET 662
Cdd:pfam00878    1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACVK--PEDVDCQVTDA-AGNEYDLSSLSRYsKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 127295      663 DKYE-----FHINVCGP-VSVGACPPDSGACQVSRSdrKSWNLGRSNAKLSYYDGMIQLTYRDGTPYN 724
Cdd:pfam00878   78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDKG--KSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
731-883 1.46e-27

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 110.28  E-value: 1.46e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      731 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECIVTDPVTlDQYDLSRLAKSEGgpggNWYSLDN 807
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295      808 GGARSTwRKYYINVCRPLNPVPGCDRYASACQMkyqGEQGSYsetvsisNLGVAKTGPMVEDsGSLLLEYVNGSAC 883
Cdd:pfam00878   79 SGDGKK-RHFYINVCHPLPGIPGCPSAAGVCLV---DKGKSW-------NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
FN2 smart00059
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ...
1906-1951 4.07e-19

Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function.


Pssm-ID: 128373  Cd Length: 49  Bit Score: 82.73  E-value: 4.07e-19
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 127295      1906 TEDGEPCVFPFVFNGKSYEECVVESRAR--LWCATTANYDRDHEWGFC 1951
Cdd:smart00059    2 NSDGEPCVFPFIYNGKKYHDCTSEGRSDgmLWCSTTPNYDRDGKWGFC 49
FN2 cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ...
1906-1951 9.13e-19

Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.


Pssm-ID: 238019  Cd Length: 48  Bit Score: 81.58  E-value: 9.13e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 127295   1906 TEDGEPCVFPFVFNGKSYEECVVESRA--RLWCATTANYDRDHEWGFC 1951
Cdd:cd00062    1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1475-1608 3.49e-18

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 83.31  E-value: 3.49e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1475 RKKSTTIRFTCSESHVNSRPMFISAV-EDCEYTFSWPTAAACAVKSNVhdDCQVTNPAtGHLFDLSSLSGRAG-----FT 1548
Cdd:pfam00878    2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweavDT 78
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 127295     1549 AAYSEKGLVYLSVCGDN---ENCANGVGACF--GQTRISVGKASKRLTYVDQVLQLVYEGGSPCP 1608
Cdd:pfam00878   79 SGDGKKRHFYINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
131-271 5.04e-16

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 77.15  E-value: 5.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      131 KIQSSITFLCGKTL--GTPEFVTAT--DCVHYFEWRTTAACKKnifkaNKEVPCYAFDRELKKHDLNPLIKTSGAYLVDD 206
Cdd:pfam00878    3 QRATIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVD 77
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 127295      207 SDPDTS---LFINVCRdievlraSSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKlVSNDRLVLSYV 271
Cdd:pfam00878   78 TSGDGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYV 137
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1768-1903 5.50e-16

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 77.15  E-value: 5.50e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1768 TSLITFHCKRGVSMGTPKLLR--TSVCDFVFEWETPLVCPDEVKTDgCSLTDEQlYYSFNLSSLSKS-------TFKVTR 1838
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYACVKPEDVD-CQVTDAA-GNEYDLSSLSRYsknweavDTSGDG 82
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295     1839 GPHTYSVGVCTAAAGLDegGCK-DGAVCLLSGSKGASFGRLaSMKLDYrhQDEAVILSYANGDTCP 1903
Cdd:pfam00878   83 KKRHFYINVCHPLPGIP--GCPsAAGVCLVDKGKSWNLGVV-QSSPQK--TNGSIQLSYVNGDLCG 143
fn2 pfam00040
Fibronectin type II domain;
1912-1951 9.01e-16

Fibronectin type II domain;


Pssm-ID: 459645  Cd Length: 42  Bit Score: 72.99  E-value: 9.01e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 127295     1912 CVFPFVFNGKSYEECVVESRA--RLWCATTANYDRDHEWGFC 1951
Cdd:pfam00040    1 CVFPFKYKGKWYHTCTTDGRRsgRLWCATTANYDGDGKWGYC 42
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1617-1740 1.08e-15

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 76.38  E-value: 1.08e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1617 SVISFVCRPEVGPtNRPMLISLDKRTCTLFFSWHTPLACEQT--TECSVRNGSSL-IDLSPLIHRTGGYEAYDESEDDGS 1693
Cdd:pfam00878    6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACVKPedVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 127295     1694 DTspdFYINICQPLNPMHGlaCPAGTAVCKVPVDGpPIDIGRVAGPP 1740
Cdd:pfam00878   85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
1958-2092 2.35e-12

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 66.75  E-value: 2.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1958 RTSVIIFKCDEDADVGRPQVFSEVRG-CEVTFEWKTKVVCPPKK-MECKFV-QKHRTYDLRLLSSLTGSWSFVHNGAS-- 2032
Cdd:pfam00878    4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVDTSGDgk 83
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 127295     2033 ---YYINLCQKIYKGPqDCSERASVCKKSTSGEVQvLGLVHTqKLDVVDDRVIVTYSKGHYCG 2092
Cdd:pfam00878   84 krhFYINVCHPLPGIP-GCPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
649-772 5.32e-08

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 56.32  E-value: 5.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      649 LTPLTKKDAYKVETDKYEFHINVCGPvsVGACPPDSGACQVSRSDRKSWNLGR-SNAKLSYYDGMIQLTYRDGTPYNN-- 725
Cdd:pfam02157   32 LANKSFEVTVGSGPETYTYNFRVCRE--VGKTASDAGLVQIDKKNGKETVIGRiNETQVFNGSDWIMLIYKGGDEYGShc 109
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 127295      726 --EKRtpRAtLITFLCDRDAGVG-----FPEYQEEDNSTYNFRWYTSYACPEEP 772
Cdd:pfam02157  110 gkEKR--KA-IIMISCNRKVLADnftivIEEREKEQDCFYLFELDSSLACPPED 160
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
1262-1374 2.55e-07

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 54.40  E-value: 2.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1262 GEYTYYFRVCGEltsgVCPTSDKSKVIsscQEKRGPQGfQKVAGLFNQklTYE-NGV--LKMNYTGGDT----CHKvYQR 1334
Cdd:pfam02157   46 ETYTYNFRVCRE----VGKTASDAGLV---QIDKKNGK-ETVIGRINE--TQVfNGSdwIMLIYKGGDEygshCGK-EKR 114
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 127295     1335 STTIFFYCDRSTQAPVFL------QETSDCSYLFEWRTQYACPPYD 1374
Cdd:pfam02157  115 KAIIMISCNRKVLADNFTivieerEKEQDCFYLFELDSSLACPPED 160
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2250-2309 6.44e-06

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 48.26  E-value: 6.44e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 127295     2250 SSTIFFHCDPLVKDGIPEFSHET-ADCQYLFSWHTSAVCPLGAGFDEEIAgDDAQEHKGLS 2309
Cdd:pfam00878    5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDVDCQVT-DAAGNEYDLS 64
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
330-485 1.55e-05

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 49.01  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      330 ESRSCSL-SSAQHDVAVDLQPLSRVEASDSLFY----TSEADEYTYYLSICG--GSQAPicnkkDAAVCQVKKADSTQVk 402
Cdd:pfam02157    5 EEKKCDLvGEESSESQKERALLKRLEPLANKSFevtvGSGPETYTYNFRVCRevGKTAS-----DAGLVQIDKKNGKET- 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      403 VAGRPQNLTLRYSDGDLTLIYFGGEECSS---GFQRMSVINFECNQ--TAGNngrgapvFT-------GEVDCTYFFTWD 470
Cdd:pfam02157   79 VIGRINETQVFNGSDWIMLIYKGGDEYGShcgKEKRKAIIMISCNRkvLADN-------FTivieereKEQDCFYLFELD 151
                          170
                   ....*....|....*
gi 127295      471 TKYACVHEKEALLCG 485
Cdd:pfam02157  152 SSLACPPEDSHLSVG 166
ATG27 pfam09451
Autophagy-related protein 27;
2002-2135 3.62e-05

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 47.71  E-value: 3.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2002 ECKFVQKHRTYDLrllSSLTGSWSFVH---------NgASYYINLCQ-----KIYKGPQDCSERASVC------KKSTSG 2061
Cdd:pfam09451   18 DCSVDKGLKKYDL---SKLKGPHSVSTtrdtppsttN-TTWTINICEplkkdKDVDKPDQCPKGTRVCgitrviLDGDDR 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2062 EVQVLGlVHTQKLDVV---------DDRVIVTYSKGHYcGDNKtASAVIELTCAKtvGRPSFTRFDV--DSCTYHFSWDS 2130
Cdd:pfam09451   94 ITQVIP-IGGSNLDPEvtrlktsdeKEGLRLTLKGGKW-GGNK-QDAIIEFICDS--DSLTFVSYDGsqEDDKLRLEWKT 168

                   ....*
gi 127295     2131 RAACA 2135
Cdd:pfam09451  169 KYACE 173
ATG27 pfam09451
Autophagy-related protein 27;
481-626 4.18e-05

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 47.71  E-value: 4.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      481 ALLCGVSDGKQRFDLSALARHSELEqnWEAVDGSQREAEKkhFFINICHRVLQTGQAR---GCPEDAAVCA---VDKNGS 554
Cdd:pfam09451   16 AFDCSVDKGLKKYDLSKLKGPHSVS--TTRDTPPSTTNTT--WTINICEPLKKDKDVDkpdQCPKGTRVCGitrVILDGD 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      555 KNLGRFIS--------SPTR-----EKGNIQLSYSDGDecGGGQKIITNITLMCKPGDLESapVLTTSRADGCFYEFEWR 621
Cdd:pfam09451   92 DRITQVIPiggsnldpEVTRlktsdEKEGLRLTLKGGK--WGGNKQDAIIEFICDSDSLTF--VSYDGSQEDDKLRLEWK 167

                   ....*
gi 127295      622 TAAAC 626
Cdd:pfam09451  168 TKYAC 172
ATG27 pfam09451
Autophagy-related protein 27;
1643-1724 5.94e-05

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 47.33  E-value: 5.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1643 CTLFFSWHTPLACEQTTECSVRNGSSLIDLSPLihrTGGYEAYDESEDDGSDTSPDFYINICQPLNPMHGLA----CPAG 1718
Cdd:pfam09451    1 LLLLLPLLAAASAVSAFDCSVDKGLKKYDLSKL---KGPHSVSTTRDTPPSTTNTTWTINICEPLKKDKDVDkpdqCPKG 77

                   ....*.
gi 127295     1719 TAVCKV 1724
Cdd:pfam09451   78 TRVCGI 83
Man-6-P_recep pfam02157
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ...
2173-2288 1.24e-03

Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.


Pssm-ID: 460468  Cd Length: 254  Bit Score: 43.23  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2173 VRTNGDRYIYEIQLSSITGSSSPacsGASICQRKANDQHfSRKVGTSNQTryYVQDGDLDVVFT------SSSKCGKDKT 2246
Cdd:pfam02157   41 VGSGPETYTYNFRVCREVGKTAS---DAGLVQIDKKNGK-ETVIGRINET--QVFNGSDWIMLIykggdeYGSHCGKEKR 114
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 127295     2247 KSVsstIFFHCDPLVKDG----IPEFSHETADCQYLFSWHTSAVCP 2288
Cdd:pfam02157  115 KAI---IMISCNRKVLADnftiVIEEREKEQDCFYLFELDSSLACP 157
ATG27 pfam09451
Autophagy-related protein 27;
635-769 2.43e-03

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 42.32  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      635 NCTVfdSQAGFSFDLTPLtkKDAYKVETD--------KYEFHINVCGPVS-------VGACPPDSGACQVSRSDRKSWNL 699
Cdd:pfam09451   18 DCSV--DKGLKKYDLSKL--KGPHSVSTTrdtppsttNTTWTINICEPLKkdkdvdkPDQCPKGTRVCGITRVILDGDDR 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295      700 --------GRSNA------KLSYYDGMIQLTYRDGTpynnEKRTPRATLITFLCDRDAgVGFPEYQ-EEDNSTYNFRWYT 764
Cdd:pfam09451   94 itqvipigGSNLDpevtrlKTSDEKEGLRLTLKGGK----WGGNKQDAIIEFICDSDS-LTFVSYDgSQEDDKLRLEWKT 168

                   ....*
gi 127295      765 SYACP 769
Cdd:pfam09451  169 KYACE 173
CIMR pfam00878
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ...
2098-2242 3.79e-03

Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.


Pssm-ID: 425923  Cd Length: 143  Bit Score: 40.17  E-value: 3.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     2098 SAVIELTCAKTV--GRPSFTRFDVDSCTYHFSWDSRAACaVKPqevQMVNGTITNPAnGRSFSLGDI--YFKRFSAsgdV 2173
Cdd:pfam00878    5 ATIIRFVCNDTAynGAPVFLHEDIGDCSYFFEWETAYAC-VKP---EDVDCQVTDAA-GNEYDLSSLsrYSKNWEA---V 76
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 127295     2174 RTNGD--RYIYEIQLSSITGSSSPACSGASICQRKANDqhfSRKVGTSNQTRYYVqDGDLDVVFTSSSKCG 2242
Cdd:pfam00878   77 DTSGDgkKRHFYINVCHPLPGIPGCPSAAGVCLVDKGK---SWNLGVVQSSPQKT-NGSIQLSYVNGDLCG 143
ATG27 pfam09451
Autophagy-related protein 27;
1244-1371 4.86e-03

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 41.17  E-value: 4.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1244 GNLYNLIPLGLNDTVVRAGE-------YTYYFRVCGELTSGV-------CPTSDkskviSSCQEKR----GPQGFQKVAG 1305
Cdd:pfam09451   25 LKKYDLSKLKGPHSVSTTRDtppsttnTTWTINICEPLKKDKdvdkpdqCPKGT-----RVCGITRvildGDDRITQVIP 99
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 127295     1306 LFNQKLTYENGVLK---------MNYTGGDtcHKVYQRSTTIFFYCD-RSTQAPVFLQETSDCSYLFEWRTQYACP 1371
Cdd:pfam09451  100 IGGSNLDPEVTRLKtsdekeglrLTLKGGK--WGGNKQDAIIEFICDsDSLTFVSYDGSQEDDKLRLEWKTKYACE 173
ATG27 pfam09451
Autophagy-related protein 27;
1082-1227 6.46e-03

Autophagy-related protein 27;


Pssm-ID: 430622  Cd Length: 261  Bit Score: 40.78  E-value: 6.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1082 TALACVPSPVDCQVtDPAGNEYDLSGLSKARKPWTAVDTFDEGKKRTFYLSVCTPL------PYIPGC-HGTAVgcCLVT 1154
Cdd:pfam09451    8 LAAASAVSAFDCSV-DKGLKKYDLSKLKGPHSVSTTRDTPPSTTNTTWTINICEPLkkdkdvDKPDQCpKGTRV--CGIT 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127295     1155 EDSKLNL-GVVQISPQVGAN--------------GSLSLVYvNGDKCKNQRFSTRINLEC-AHTTGSPTFQLQNDCEYVF 1218
Cdd:pfam09451   85 RVILDGDdRITQVIPIGGSNldpevtrlktsdekEGLRLTL-KGGKWGGNKQDAIIEFICdSDSLTFVSYDGSQEDDKLR 163
                          170
                   ....*....|
gi 127295     1219 L-WRTVEACP 1227
Cdd:pfam09451  164 LeWKTKYACE 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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