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Conserved domains on  [gi|1252002499|dbj|BBA58524|]
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capsular polysaccharide biosynthesis protein CpsC [Streptococcus pneumoniae]

Protein Classification

capsular polysaccharide biosynthesis protein( domain architecture ID 11490076)

capsular polysaccharide biosynthesis protein similar to Streptococcus pneumoniae capsular polysaccharide biosynthesis protein CpsC, as well as Staphylococcus aureus capsular polysaccharide type 8 biosynthesis protein cap8A and capsular polysaccharide type 5 biosynthesis protein cap5A

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
polys_exp_MPA1 TIGR01006
polysaccharide export protein, MPA1 family, Gram-positive type; This family contains members ...
1-228 4.54e-109

polysaccharide export protein, MPA1 family, Gram-positive type; This family contains members from Low GC Gram-positive bacteria; they are proposed to have a function in the export of complex polysaccharides. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


:

Pssm-ID: 130079 [Multi-domain]  Cd Length: 226  Bit Score: 312.86  E-value: 4.54e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   1 MKEQNTlEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVIKPEFTSMTRIYVVNRDQGEKsGLTNQDLQAGLSLVK 80
Cdd:TIGR01006   1 MKQENT-EIDLLQLLKKLWKRKLLILIVALIFLIISFIYTFFIISPEYTSTTRIYVVNRNQDNK-GLTAQDLQAGIQLVN 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499  81 DYREIILSQDVLEEVVSDLKLDLTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT 160
Cdd:TIGR01006  79 DYKEIILSPDILDKVSKDLKLDLSPKELSSMVTVTNPTDTRLISISVKDKTPQDASKIANSLREVASKKIPKITNVSDVT 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1252002499 161 TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLQMTLLGIVPNLNK 228
Cdd:TIGR01006 159 TLEEAKPATTPSSPNPKRNLLIGFLLGLVVALIIVLLKELLDTRVKRPEDVEDVLGMTLLGIVPDFDK 226
 
Name Accession Description Interval E-value
polys_exp_MPA1 TIGR01006
polysaccharide export protein, MPA1 family, Gram-positive type; This family contains members ...
1-228 4.54e-109

polysaccharide export protein, MPA1 family, Gram-positive type; This family contains members from Low GC Gram-positive bacteria; they are proposed to have a function in the export of complex polysaccharides. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 130079 [Multi-domain]  Cd Length: 226  Bit Score: 312.86  E-value: 4.54e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   1 MKEQNTlEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVIKPEFTSMTRIYVVNRDQGEKsGLTNQDLQAGLSLVK 80
Cdd:TIGR01006   1 MKQENT-EIDLLQLLKKLWKRKLLILIVALIFLIISFIYTFFIISPEYTSTTRIYVVNRNQDNK-GLTAQDLQAGIQLVN 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499  81 DYREIILSQDVLEEVVSDLKLDLTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT 160
Cdd:TIGR01006  79 DYKEIILSPDILDKVSKDLKLDLSPKELSSMVTVTNPTDTRLISISVKDKTPQDASKIANSLREVASKKIPKITNVSDVT 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1252002499 161 TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLQMTLLGIVPNLNK 228
Cdd:TIGR01006 159 TLEEAKPATTPSSPNPKRNLLIGFLLGLVVALIIVLLKELLDTRVKRPEDVEDVLGMTLLGIVPDFDK 226
YveK COG3944
Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];
8-224 1.39e-60

Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443144 [Multi-domain]  Cd Length: 309  Bit Score: 192.59  E-value: 1.39e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIItSSVAFAYSTFVIKPEFTSMTRIYVvNRDQGEKSGLTNQDLQAGLSLVKDYREIIL 87
Cdd:COG3944     1 EMDLREYLRILRRRWWLILLLTLL-GALAALASSFLITPVYQASTTLLV-STSSGSDASDLYQGIQTAQQLVNTYAELLK 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499  88 SQDVLEEVVSDLKLDLTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVTTLEEARP 167
Cdd:COG3944    79 SPAVLEEVIDELGLDLSPEELAKKISVTSPPDTQVITITVTDTDPERAADIANAVAEVFAEEVKELMKVDNVTVLDPATV 158
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1252002499 168 ATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLQMTLLGIVP 224
Cdd:COG3944   159 PASPVSPNPKLNLAIGLVLGLLLGVGLAFLRELLDTTIRSEEDIERLLGLLLGGAVP 215
Wzz pfam02706
Chain length determinant protein; This family includes proteins involved in lipopolysaccharide ...
8-98 3.46e-22

Chain length determinant protein; This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases.


Pssm-ID: 460658 [Multi-domain]  Cd Length: 90  Bit Score: 86.57  E-value: 3.46e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIITSSVAFAYStFVIKPEFTSMTRIYVVNRDQGEKSgLTNQDLQAGLSLVKDYREIIL 87
Cdd:pfam02706   2 EIDLIELLGVLWKRKKLIILVTLLFTLLAAAYA-FLATPKYTATAQILVPQKKGEAGS-LLGSDLQAGLQLASTEIEILK 79
                          90
                  ....*....|.
gi 1252002499  88 SQDVLEEVVSD 98
Cdd:pfam02706  80 SRDVLEKVIDE 90
PRK11638 PRK11638
ECA polysaccharide chain length modulation protein;
8-87 1.77e-04

ECA polysaccharide chain length modulation protein;


Pssm-ID: 236943 [Multi-domain]  Cd Length: 342  Bit Score: 41.95  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIITSSVAFAYStFVIKPEF--TSMTRIYVVNRDQGEKSG---LTNQDLQAGLSLVKD- 81
Cdd:PRK11638    9 ELDIRGLCRTLWAGKLWIIGMALLFALIALGYS-FLARQEWsaTAITDRPTVNMLGGYYSQqqfLRNLDIRSNSALSADq 87
                          90
                  ....*....|...
gi 1252002499  82 -------YREIIL 87
Cdd:PRK11638   88 psimdeaYKEFIM 100
 
Name Accession Description Interval E-value
polys_exp_MPA1 TIGR01006
polysaccharide export protein, MPA1 family, Gram-positive type; This family contains members ...
1-228 4.54e-109

polysaccharide export protein, MPA1 family, Gram-positive type; This family contains members from Low GC Gram-positive bacteria; they are proposed to have a function in the export of complex polysaccharides. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 130079 [Multi-domain]  Cd Length: 226  Bit Score: 312.86  E-value: 4.54e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   1 MKEQNTlEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVIKPEFTSMTRIYVVNRDQGEKsGLTNQDLQAGLSLVK 80
Cdd:TIGR01006   1 MKQENT-EIDLLQLLKKLWKRKLLILIVALIFLIISFIYTFFIISPEYTSTTRIYVVNRNQDNK-GLTAQDLQAGIQLVN 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499  81 DYREIILSQDVLEEVVSDLKLDLTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT 160
Cdd:TIGR01006  79 DYKEIILSPDILDKVSKDLKLDLSPKELSSMVTVTNPTDTRLISISVKDKTPQDASKIANSLREVASKKIPKITNVSDVT 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1252002499 161 TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLQMTLLGIVPNLNK 228
Cdd:TIGR01006 159 TLEEAKPATTPSSPNPKRNLLIGFLLGLVVALIIVLLKELLDTRVKRPEDVEDVLGMTLLGIVPDFDK 226
YveK COG3944
Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];
8-224 1.39e-60

Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443144 [Multi-domain]  Cd Length: 309  Bit Score: 192.59  E-value: 1.39e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIItSSVAFAYSTFVIKPEFTSMTRIYVvNRDQGEKSGLTNQDLQAGLSLVKDYREIIL 87
Cdd:COG3944     1 EMDLREYLRILRRRWWLILLLTLL-GALAALASSFLITPVYQASTTLLV-STSSGSDASDLYQGIQTAQQLVNTYAELLK 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499  88 SQDVLEEVVSDLKLDLTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVTTLEEARP 167
Cdd:COG3944    79 SPAVLEEVIDELGLDLSPEELAKKISVTSPPDTQVITITVTDTDPERAADIANAVAEVFAEEVKELMKVDNVTVLDPATV 158
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1252002499 168 ATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLQMTLLGIVP 224
Cdd:COG3944   159 PASPVSPNPKLNLAIGLVLGLLLGVGLAFLRELLDTTIRSEEDIERLLGLLLGGAVP 215
Wzz pfam02706
Chain length determinant protein; This family includes proteins involved in lipopolysaccharide ...
8-98 3.46e-22

Chain length determinant protein; This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases.


Pssm-ID: 460658 [Multi-domain]  Cd Length: 90  Bit Score: 86.57  E-value: 3.46e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIITSSVAFAYStFVIKPEFTSMTRIYVVNRDQGEKSgLTNQDLQAGLSLVKDYREIIL 87
Cdd:pfam02706   2 EIDLIELLGVLWKRKKLIILVTLLFTLLAAAYA-FLATPKYTATAQILVPQKKGEAGS-LLGSDLQAGLQLASTEIEILK 79
                          90
                  ....*....|.
gi 1252002499  88 SQDVLEEVVSD 98
Cdd:pfam02706  80 SRDVLEKVIDE 90
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
8-145 2.66e-19

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 86.22  E-value: 2.66e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIITSSVAFAYsTFVIKPEFTSMTRIYVvnRDQGEKSGLTN-QDLQAGLSLVKDYREII 86
Cdd:COG3206    14 EIDLRDLLRILRRRKWLILLVFLLVLALALLY-ALLLPPVYEASATLLV--EPQSSDVLLSGlSSLSASDSPLETQIEIL 90
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499  87 LSQDVLEEVVSDLKLDLTP-----------KDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREV 145
Cdd:COG3206    91 KSRPVLERVVDKLNLDEDPlgeeasreaaiERLRKNLTVEPVKGSNVIEISYTSPDPELAAAVANALAEA 160
WzzB COG3765
LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope ...
8-149 5.80e-09

LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442979 [Multi-domain]  Cd Length: 364  Bit Score: 55.36  E-value: 5.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIITSSVAFAYStFVIKPEFTSmtRIYVVNRDQGEKSGLTNQDLQAGLSLVKDYREIIL 87
Cdd:COG3765    21 EIDLFELLRTLWQGKLWIIGITLLFALLALVYA-FLLPQKWTS--TAIVDPPTVNELGGYYSQRQFLRNLDVKSVDPPVI 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499  88 SQDVLEEVV---------------SDLKLDLTPKD----------LANKIKVTVPVDTR------IVSVSVSDRVPEEAS 136
Cdd:COG3765    98 SSELFNEFIkqlssydlrrefllqSDYYKQLQEGDekedaalldeLINNISITPPDDKKksspytNYSVSFTAETPEDAQ 177
                         170
                  ....*....|...
gi 1252002499 137 RIANSLREVAAQK 149
Cdd:COG3765   178 QLLRGYIDFANQR 190
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
155-228 2.89e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.40  E-value: 2.89e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1252002499 155 RVSDVTTLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLQMTLLGIVPNLNK 228
Cdd:COG3206   384 TVGNVRVIDPAVVPLKPVSPKKLLILALGLLLGLLLGLGLALLLELLDRTIEEELELLLLLGLPLLGPLPPLKS 457
PRK11638 PRK11638
ECA polysaccharide chain length modulation protein;
8-87 1.77e-04

ECA polysaccharide chain length modulation protein;


Pssm-ID: 236943 [Multi-domain]  Cd Length: 342  Bit Score: 41.95  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1252002499   8 EIDVLQLFRALWKRKLVILLVAIITSSVAFAYStFVIKPEF--TSMTRIYVVNRDQGEKSG---LTNQDLQAGLSLVKD- 81
Cdd:PRK11638    9 ELDIRGLCRTLWAGKLWIIGMALLFALIALGYS-FLARQEWsaTAITDRPTVNMLGGYYSQqqfLRNLDIRSNSALSADq 87
                          90
                  ....*....|...
gi 1252002499  82 -------YREIIL 87
Cdd:PRK11638   88 psimdeaYKEFIM 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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