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Conserved domains on  [gi|1239396240|sp|P0DP87|]
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RecName: Full=Apolipoprotein A-II; Short=Apo-AII; Short=ApoA-II; AltName: Full=Apolipoprotein A2; Contains: RecName: Full=Proapolipoprotein A-II; Short=ProapoA-II; Contains: RecName: Full=Truncated apolipoprotein A-II; Flags: Precursor

Protein Classification

ApoA-II domain-containing protein( domain architecture ID 10520240)

ApoA-II domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ApoA-II pfam04711
Apolipoprotein A-II (ApoA-II); Apolipoprotein A-II (ApoA-II) is the second major ...
 1-98 2.21e-47

Apolipoprotein A-II (ApoA-II); Apolipoprotein A-II (ApoA-II) is the second major apolipoprotein of high density lipoprotein in human plasma. Mature ApoA-II is present as a dimer of two 77-amino acid chains joined by a disulphide bridge. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. In bovine serum, the ApoA-II homolog is present in almost free form. Bovine ApoA-II shows antimicrobial activity against Escherichia coli and yeasts in phosphate buffered saline (PBS).


:

Pssm-ID: 461404  Cd Length: 99  Bit Score: 146.45  E-value: 2.21e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239396240   1 MKLLAATVLLLTICSLEGALVRRQAEEPSVESLVSQYFQTVTDYGKDLMEKVKSPELQAQAKAYFEKSKEQLTPLVKKAG 80
Cdd:pfam04711   1 MKLLAMTVLLLTICSLEGALVRRQAEEPDLQSLFSQYFQTLTDYGKDLVEKAKGPELQAQAKAYFEKTQEQLTPLVKKAG 80

                          90
                  ....*....|....*....
gi 1239396240  81 TDLVNFLSYFVEL-RTQPA 98
Cdd:pfam04711  81 TDLMNFFSNFVDLkKPQPA 99
 
Name Accession Description Interval E-value
ApoA-II pfam04711
Apolipoprotein A-II (ApoA-II); Apolipoprotein A-II (ApoA-II) is the second major ...
 1-98 2.21e-47

Apolipoprotein A-II (ApoA-II); Apolipoprotein A-II (ApoA-II) is the second major apolipoprotein of high density lipoprotein in human plasma. Mature ApoA-II is present as a dimer of two 77-amino acid chains joined by a disulphide bridge. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. In bovine serum, the ApoA-II homolog is present in almost free form. Bovine ApoA-II shows antimicrobial activity against Escherichia coli and yeasts in phosphate buffered saline (PBS).


Pssm-ID: 461404  Cd Length: 99  Bit Score: 146.45  E-value: 2.21e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239396240   1 MKLLAATVLLLTICSLEGALVRRQAEEPSVESLVSQYFQTVTDYGKDLMEKVKSPELQAQAKAYFEKSKEQLTPLVKKAG 80
Cdd:pfam04711   1 MKLLAMTVLLLTICSLEGALVRRQAEEPDLQSLFSQYFQTLTDYGKDLVEKAKGPELQAQAKAYFEKTQEQLTPLVKKAG 80

                          90
                  ....*....|....*....
gi 1239396240  81 TDLVNFLSYFVEL-RTQPA 98
Cdd:pfam04711  81 TDLMNFFSNFVDLkKPQPA 99
 
Name Accession Description Interval E-value
ApoA-II pfam04711
Apolipoprotein A-II (ApoA-II); Apolipoprotein A-II (ApoA-II) is the second major ...
 1-98 2.21e-47

Apolipoprotein A-II (ApoA-II); Apolipoprotein A-II (ApoA-II) is the second major apolipoprotein of high density lipoprotein in human plasma. Mature ApoA-II is present as a dimer of two 77-amino acid chains joined by a disulphide bridge. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. In bovine serum, the ApoA-II homolog is present in almost free form. Bovine ApoA-II shows antimicrobial activity against Escherichia coli and yeasts in phosphate buffered saline (PBS).


Pssm-ID: 461404  Cd Length: 99  Bit Score: 146.45  E-value: 2.21e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239396240   1 MKLLAATVLLLTICSLEGALVRRQAEEPSVESLVSQYFQTVTDYGKDLMEKVKSPELQAQAKAYFEKSKEQLTPLVKKAG 80
Cdd:pfam04711   1 MKLLAMTVLLLTICSLEGALVRRQAEEPDLQSLFSQYFQTLTDYGKDLVEKAKGPELQAQAKAYFEKTQEQLTPLVKKAG 80

                          90
                  ....*....|....*....
gi 1239396240  81 TDLVNFLSYFVEL-RTQPA 98
Cdd:pfam04711  81 TDLMNFFSNFVDLkKPQPA 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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