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Conserved domains on  [gi|1236518668|ref|YP_009414333|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Phaner pallescens]

Protein Classification

NADH-ubiquinone oxidoreductase chain 4L( domain architecture ID 10009568)

NADH-ubiquinone oxidoreductase chain 4L is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is believed to belong to the minimal assembly required for catalysis; Complex I functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 9.64e-38

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177169  Cd Length: 98  Bit Score: 121.96  E-value: 9.64e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  1 MLSISTNIILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1236518668 81 VSNTYGLDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 9.64e-38

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 121.96  E-value: 9.64e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  1 MLSISTNIILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1236518668 81 VSNTYGLDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 1.08e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 53.34  E-value: 1.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  3 SISTNIILAFIIALLGMLvFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1236518668 83 NTYGLDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 9.64e-38

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 121.96  E-value: 9.64e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  1 MLSISTNIILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1236518668 81 VSNTYGLDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 11-98 1.87e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 85.79  E-value: 1.87e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668 11 AFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVSNTYGLDYV 90
Cdd:MTH00126  11 AFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVATARTHGTDRL 90


                 ....*...
gi 1236518668 91 QNLNLLQC 98
Cdd:MTH00126  91 QNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 7.89e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 79.12  E-value: 7.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  1 MLSISTNIILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVM 80
Cdd:MTH00125   1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                         90
                 ....*....|....*...
gi 1236518668 81 VSNTYGLDYVQNLNLLQC 98
Cdd:MTH00125  81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 8-98 1.49e-18

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 73.48  E-value: 1.49e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  8 IILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVSNTYGL 87
Cdd:MTH00067   8 FYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVATTRTHGT 87

                         90
                 ....*....|.
gi 1236518668 88 DYVQNLNLLQC 98
Cdd:MTH00067  88 DHLKNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 9-96 2.11e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 57.65  E-value: 2.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  9 ILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVSNTYGLD 88
Cdd:MTH00181   6 ISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSD 85


                 ....*...
gi 1236518668 89 YVQNLNLL 96
Cdd:MTH00181  86 HLLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 1.08e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 53.34  E-value: 1.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  3 SISTNIILAFIIALLGMLvFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1236518668 83 NTYGLDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 2.00e-08

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 47.22  E-value: 2.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  1 MLSISTNIILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVM 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1236518668 81 VSNTYGLDYVQNLNLLQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.01e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 47.28  E-value: 2.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  1 MLSISTNIILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFilCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVM 80
Cdd:MTH00188   2 FFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLF--WFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVS 79

                         90
                 ....*....|....*...
gi 1236518668 81 VSNTYGLDYVQNLNLLQC 98
Cdd:MTH00188  80 LIRSHGSDYVSSLNLIKC 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 8-92 7.01e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 43.22  E-value: 7.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  8 IILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILctLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVSNTYGL 87
Cdd:MTH00162   7 FLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFL--LFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSHGN 84


                 ....*
gi 1236518668 88 DYVQN 92
Cdd:MTH00162  85 DYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 9-98 1.53e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 42.52  E-value: 1.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  9 ILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILctLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVSNTYGLD 88
Cdd:MTH00149  10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVM--MFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGND 87

                         90
                 ....*....|
gi 1236518668 89 YVQNLNLLQC 98
Cdd:MTH00149  88 YVSSLSSLKF 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 1-98 2.07e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 42.05  E-value: 2.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  1 MLSISTNIILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILcTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVM 80
Cdd:MTH00013   1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALF-IPLSLMFANQVNGMLAIVLLTFGACEASLGLSLLVL 79

                         90
                 ....*....|....*...
gi 1236518668 81 VSNTYGLDYVQNLNLLQC 98
Cdd:MTH00013  80 MTRSYGNDMLKSLTSNKC 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 9-97 6.51e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 38.47  E-value: 6.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236518668  9 ILAFIIALLGMLVFRSHLMSSLLCLEGMMLSMFILCTLITLSIHFTMSFMIPIMLLVFAACEAAVGLALLVMVSNTYGLD 88
Cdd:MTH00180  10 IILFILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVAYYRIRGTI 89


                 ....*....
gi 1236518668 89 YVQNLNLLQ 97
Cdd:MTH00180  90 AVKSLNLLR 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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