MAG: hypothetical protein B7Z73_00200 [Planctomycetia bacterium 21-64-5]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
CxxCH_TIGR02603 super family | cl28188 | putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain ... |
509-637 | 8.11e-36 | |||
putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190). The actual alignment was detected with superfamily member TIGR02603: Pssm-ID: 274224 Cd Length: 133 Bit Score: 131.33 E-value: 8.11e-36
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Piru_Ver_Nterm super family | cl26818 | putative membrane-bound dehydrogenase domain; All proteins that score above the trusted cutoff ... |
2-51 | 5.00e-16 | |||
putative membrane-bound dehydrogenase domain; All proteins that score above the trusted cutoff score of 45 to this model are large proteins of either Pirellula sp. 1 or Verrucomicrobium spinosum. These proteins all contain, in addition to this domain, several hundred residues of highly variable sequence, and then a well-conserved C-terminal domain (TIGR02603) that features a putative cytochrome c-type heme binding motif CXXCH. The membrane-bound L-sorbosone dehydrogenase from Acetobacter liquefaciens (Gluconacetobacter liquefaciens) (SP|Q44091) is homologous to this domain but lacks additional sequence regions shared by members of this family and belongs to a different clade of the larger family of homologs. It and its closely related homologs are excluded from the this model by scoring between the trusted (45) and noise (18) cutoffs. The actual alignment was detected with superfamily member TIGR02604: Pssm-ID: 274225 [Multi-domain] Cd Length: 367 Bit Score: 80.18 E-value: 5.00e-16
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HEAT | COG1413 | HEAT repeat [General function prediction only]; |
80-224 | 2.38e-05 | |||
HEAT repeat [General function prediction only]; : Pssm-ID: 441023 [Multi-domain] Cd Length: 137 Bit Score: 44.62 E-value: 2.38e-05
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T3SC_I-like super family | cl38901 | class I type III secretion system (T3SS) chaperones and similar proteins; This family contains ... |
196-296 | 2.72e-03 | |||
class I type III secretion system (T3SS) chaperones and similar proteins; This family contains class I type III secretion system (T3SS) chaperones mainly found in Gram-negative bacteria such as Pseudomonas, Yersinia, Salmonella, Escherichia and Erwinia, among others. A wide variety of these bacterial pathogens and symbionts require a T3SS to inject eukaryotic host cells with effector proteins important for suppressing host defenses and establishing infection. Many of these effector proteins interact with specific type III secretion chaperones prior to secretion. These T3SS chaperones have been classified as class I type III secretion chaperones (T3SC), which are small structurally conserved dimers that interact specifically with T3SS effector proteins. Class I T3SC consists of two subclasses: IA and IB. Class IA T3SC binds a single effector, whereas class IB T3SC binds to several effectors. Class IA and Class IB T3SCs typically exhibit little sequence similarities, but share a common overall heart-shaped structure fold (alpha-beta-beta-beta-alpha-beta-beta-alpha) and features, such as a small size, an acidic pI and an amphipathic C-terminal alpha-helix. Chaperone protein CesT serves a chaperone function for the enteropathogenic Escherichia coli (EPEC) translocated intimin receptor (Tir) protein, which confers upon EPEC the ability to alter host cell morphology following intimate bacterial attachment. In Pseudomonas aeruginosa, chaperone ExsC binds small secreted protein ExsE as well as the non-secreted anti-activator protein ExsD; it relieves repression of the transcriptional activator ExsA (which activates expression of T3SS genes) by ExsD. P. aeruginosa SpcU binds the cytotoxin ExoU, which is a broad-specificity phospholipase A2 (PLA2) and lysophospholipase, and maintains the N-terminus of ExoU in an unfolded state which is required for secretion. Salmonella enterica chaperone SicP forms a complex with effector protein SptP at an early stage of its secretion process in order to avoid premature degradation, while chaperone SigE binds to effector SigD, which, upon translocation into the host cell, preferentially dephosphorylates specific inositol phospholipids that are thought to be crucial for subsequent activation of the host cell Ser-Thr kinase Akt. This family also includes Yersinia chaperone/escortee pairs SycE/YopE, SycH/YopH, SycT/YopT and SycN+YscB/YopN, all of which bind to specific Yersinia outer proteins (Yops). Also included are several DspF and related sequences from several plant pathogenic bacteria. The "disease-specific" (dsp) region next to the hrp gene cluster of Erwinia amylovora is required for pathogenicity but not for elicitation of the hypersensitive reaction. In addition, a group of proteins including Escherichia coli YbjN, Erwinia amylovora AmyR, and their homologs, are included in this family. They share a class I T3SC-like fold with T3SS chaperone proteins but appear to function independently of the T3SS. The actual alignment was detected with superfamily member cd17025: Pssm-ID: 422950 Cd Length: 124 Bit Score: 38.42 E-value: 2.72e-03
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Name | Accession | Description | Interval | E-value | |||||
CxxCH_TIGR02603 | TIGR02603 | putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain ... |
509-637 | 8.11e-36 | |||||
putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190). Pssm-ID: 274224 Cd Length: 133 Bit Score: 131.33 E-value: 8.11e-36
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Piru_Ver_Nterm | TIGR02604 | putative membrane-bound dehydrogenase domain; All proteins that score above the trusted cutoff ... |
2-51 | 5.00e-16 | |||||
putative membrane-bound dehydrogenase domain; All proteins that score above the trusted cutoff score of 45 to this model are large proteins of either Pirellula sp. 1 or Verrucomicrobium spinosum. These proteins all contain, in addition to this domain, several hundred residues of highly variable sequence, and then a well-conserved C-terminal domain (TIGR02603) that features a putative cytochrome c-type heme binding motif CXXCH. The membrane-bound L-sorbosone dehydrogenase from Acetobacter liquefaciens (Gluconacetobacter liquefaciens) (SP|Q44091) is homologous to this domain but lacks additional sequence regions shared by members of this family and belongs to a different clade of the larger family of homologs. It and its closely related homologs are excluded from the this model by scoring between the trusted (45) and noise (18) cutoffs. Pssm-ID: 274225 [Multi-domain] Cd Length: 367 Bit Score: 80.18 E-value: 5.00e-16
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Cytochrom_C | pfam00034 | Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and ... |
513-557 | 8.50e-06 | |||||
Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family. Pssm-ID: 459641 [Multi-domain] Cd Length: 89 Bit Score: 44.45 E-value: 8.50e-06
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HEAT | COG1413 | HEAT repeat [General function prediction only]; |
80-224 | 2.38e-05 | |||||
HEAT repeat [General function prediction only]; Pssm-ID: 441023 [Multi-domain] Cd Length: 137 Bit Score: 44.62 E-value: 2.38e-05
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HEAT_2 | pfam13646 | HEAT repeats; This family includes multiple HEAT repeats. |
105-203 | 4.13e-05 | |||||
HEAT repeats; This family includes multiple HEAT repeats. Pssm-ID: 433376 [Multi-domain] Cd Length: 88 Bit Score: 42.32 E-value: 4.13e-05
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Cyc7 | COG3474 | Cytochrome c2 [Energy production and conversion]; |
509-545 | 7.32e-05 | |||||
Cytochrome c2 [Energy production and conversion]; Pssm-ID: 442697 [Multi-domain] Cd Length: 101 Bit Score: 42.18 E-value: 7.32e-05
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PRK13800 | PRK13800 | fumarate reductase/succinate dehydrogenase flavoprotein subunit; |
55-334 | 9.15e-05 | |||||
fumarate reductase/succinate dehydrogenase flavoprotein subunit; Pssm-ID: 237512 [Multi-domain] Cd Length: 897 Bit Score: 45.61 E-value: 9.15e-05
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T3SC_IA_ShcF-like | cd17025 | Class IA type III secretion system chaperone protein, similar to Pseudomonas syringae ShcF; ... |
196-296 | 2.72e-03 | |||||
Class IA type III secretion system chaperone protein, similar to Pseudomonas syringae ShcF; This family includes type III secretion system (T3SS) chaperone proteins similar to Pseudomonas syringae ShcF and similar proteins. In P. syringae, which is a plant pathogen that can infect a wide range of species, the T3SS allows injection of the effector protein AvrPphF into genetically susceptible host cells. Chaperone ShcF (originally known as AvrPphF ORD1) binds AvrPphF in a similar manner to type III chaperones from bacterial pathogens of animals, indicating structural conservation of these specialized chaperones, despite high sequence divergence. Pssm-ID: 409309 Cd Length: 124 Bit Score: 38.42 E-value: 2.72e-03
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Name | Accession | Description | Interval | E-value | |||||
CxxCH_TIGR02603 | TIGR02603 | putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain ... |
509-637 | 8.11e-36 | |||||
putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190). Pssm-ID: 274224 Cd Length: 133 Bit Score: 131.33 E-value: 8.11e-36
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Piru_Ver_Nterm | TIGR02604 | putative membrane-bound dehydrogenase domain; All proteins that score above the trusted cutoff ... |
2-51 | 5.00e-16 | |||||
putative membrane-bound dehydrogenase domain; All proteins that score above the trusted cutoff score of 45 to this model are large proteins of either Pirellula sp. 1 or Verrucomicrobium spinosum. These proteins all contain, in addition to this domain, several hundred residues of highly variable sequence, and then a well-conserved C-terminal domain (TIGR02603) that features a putative cytochrome c-type heme binding motif CXXCH. The membrane-bound L-sorbosone dehydrogenase from Acetobacter liquefaciens (Gluconacetobacter liquefaciens) (SP|Q44091) is homologous to this domain but lacks additional sequence regions shared by members of this family and belongs to a different clade of the larger family of homologs. It and its closely related homologs are excluded from the this model by scoring between the trusted (45) and noise (18) cutoffs. Pssm-ID: 274225 [Multi-domain] Cd Length: 367 Bit Score: 80.18 E-value: 5.00e-16
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Cytochrom_C | pfam00034 | Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and ... |
513-557 | 8.50e-06 | |||||
Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family. Pssm-ID: 459641 [Multi-domain] Cd Length: 89 Bit Score: 44.45 E-value: 8.50e-06
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HEAT | COG1413 | HEAT repeat [General function prediction only]; |
80-224 | 2.38e-05 | |||||
HEAT repeat [General function prediction only]; Pssm-ID: 441023 [Multi-domain] Cd Length: 137 Bit Score: 44.62 E-value: 2.38e-05
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HEAT_2 | pfam13646 | HEAT repeats; This family includes multiple HEAT repeats. |
105-203 | 4.13e-05 | |||||
HEAT repeats; This family includes multiple HEAT repeats. Pssm-ID: 433376 [Multi-domain] Cd Length: 88 Bit Score: 42.32 E-value: 4.13e-05
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Cyc7 | COG3474 | Cytochrome c2 [Energy production and conversion]; |
509-545 | 7.32e-05 | |||||
Cytochrome c2 [Energy production and conversion]; Pssm-ID: 442697 [Multi-domain] Cd Length: 101 Bit Score: 42.18 E-value: 7.32e-05
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PRK13800 | PRK13800 | fumarate reductase/succinate dehydrogenase flavoprotein subunit; |
55-334 | 9.15e-05 | |||||
fumarate reductase/succinate dehydrogenase flavoprotein subunit; Pssm-ID: 237512 [Multi-domain] Cd Length: 897 Bit Score: 45.61 E-value: 9.15e-05
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HEAT | COG1413 | HEAT repeat [General function prediction only]; |
99-205 | 2.62e-04 | |||||
HEAT repeat [General function prediction only]; Pssm-ID: 441023 [Multi-domain] Cd Length: 137 Bit Score: 41.54 E-value: 2.62e-04
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Cytochrome_CBB3 | pfam13442 | Cytochrome C oxidase, cbb3-type, subunit III; |
509-541 | 1.04e-03 | |||||
Cytochrome C oxidase, cbb3-type, subunit III; Pssm-ID: 463879 [Multi-domain] Cd Length: 67 Bit Score: 37.77 E-value: 1.04e-03
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CccA | COG2010 | Cytochrome c, mono- and diheme variants [Energy production and conversion]; |
500-548 | 1.95e-03 | |||||
Cytochrome c, mono- and diheme variants [Energy production and conversion]; Pssm-ID: 441613 [Multi-domain] Cd Length: 169 Bit Score: 39.55 E-value: 1.95e-03
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TsdA | COG3258 | Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion ... |
509-547 | 2.05e-03 | |||||
Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion transport and metabolism]; Pssm-ID: 442489 [Multi-domain] Cd Length: 216 Bit Score: 40.22 E-value: 2.05e-03
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T3SC_IA_ShcF-like | cd17025 | Class IA type III secretion system chaperone protein, similar to Pseudomonas syringae ShcF; ... |
196-296 | 2.72e-03 | |||||
Class IA type III secretion system chaperone protein, similar to Pseudomonas syringae ShcF; This family includes type III secretion system (T3SS) chaperone proteins similar to Pseudomonas syringae ShcF and similar proteins. In P. syringae, which is a plant pathogen that can infect a wide range of species, the T3SS allows injection of the effector protein AvrPphF into genetically susceptible host cells. Chaperone ShcF (originally known as AvrPphF ORD1) binds AvrPphF in a similar manner to type III chaperones from bacterial pathogens of animals, indicating structural conservation of these specialized chaperones, despite high sequence divergence. Pssm-ID: 409309 Cd Length: 124 Bit Score: 38.42 E-value: 2.72e-03
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Blast search parameters | ||||
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