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Conserved domains on  [gi|1229768265|ref|XP_022136957|]
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receptor-like protein 12 [Momordica charantia]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 13746049)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 285-911 9.29e-78

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 274.42  E-value: 9.29e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 285 NMTSLVSLDLSGTQVNFHSLKSFQSLRNINLLDLSGNIIRGLLSDFLKALHprvlNSLQYLSLRINEFCGFLPNfTMLPS 364
Cdd:PLN00113   67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTS----SSLRYLNLSNNNFTGSIPR-GSIPN 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 365 LKHLELSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHS 444
Cdd:PLN00113  142 LETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGY 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 445 NSLSGTIPQNLGQLSNLEYLDLHSNSLEGEVSeahfSKLINLKrldlsnnslslnlktdwvpsfQLDYIILGQCNL-GPL 523
Cdd:PLN00113  222 NNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIP----SSLGNLK---------------------NLQYLFLYQNKLsGPI 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 524 FPewlrtqtptlidiSFAGISDIVphwfwnnlspGMDLSGNKMMGEIPNLSLKFNMAPVISLKSNKFVGRIP---AFLFQ 600
Cdd:PLN00113  277 PP-------------SIFSLQKLI----------SLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPvalTSLPR 333

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 601 AEFLHLSSNDFS-----DLSGlceivNSPLETLDLSDNQLSGQLPDCWDSMLHLKILNLSNNYFFGDVPHSIGNLIHMES 675
Cdd:PLN00113  334 LQVLQLWSNKFSgeipkNLGK-----HNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRR 408

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 676 LVLRNNQFSGGLPFLF-NLTYLGVIDAMNNNLSGTIPS--WigsKIPYLTILNLKSNHFHGNLGRgLCNLKYIQILDISS 752
Cdd:PLN00113  409 VRLQDNSFSGELPSEFtKLPLVYFLDISNNNLQGRINSrkW---DMPSLQMLSLARNKFFGGLPD-SFGSKRLENLDLSR 484

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 753 NNVSGSIPTCIRNFNALTQtlfsghpnyetdifmvwkggerhitgqvmdlvrsIDLSCNHLSGKIPYEITQLVELIILNL 832
Cdd:PLN00113  485 NQFSGAVPRKLGSLSELMQ----------------------------------LKLSENKLSGEIPDELSSCKKLVSLDL 530

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1229768265 833 SRNELTGQIPDKIGRLQSLESLDLSRNHLSGPIPSHLSQVFRLGVLDLSYNNLSGKIPMGTQLQGFSTSSYEGNPYLCG 911
Cdd:PLN00113  531 SHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
PLN03150 super family cl31977
hypothetical protein; Provisional
 66-173 7.08e-07

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PLN03150:

Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.28  E-value: 7.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265  66 NNDCC-----NWSAVRCS-NKTEGHHVI---GIDLRGshdkyLKGEVGSSsLTQLSRLKYLDLSYNQFDRILLEDIGSLV 136
Cdd:PLN03150  393 NGDPCvpqqhPWSGADCQfDSTKGKWFIdglGLDNQG-----LRGFIPND-ISKLRHLQSINLSGNSIRGNIPPSLGSIT 466

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1229768265 137 NMNYLNLSYNWFKTALPPHLGNLSKLSVLDLGNNYWS 173
Cdd:PLN03150  467 SLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLS 503
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 41-78 3.42e-06

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


:

Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 44.59  E-value: 3.42e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1229768265  41 ESERQALLSFQQRLTDEYGILSSWVNN--DCCNWSAVRCS 78
Cdd:pfam08263   2 NDDGQALLAFKSSLNDPPGALSSWNSSssDPCSWTGVTCD 41
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 285-911 9.29e-78

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 274.42  E-value: 9.29e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 285 NMTSLVSLDLSGTQVNFHSLKSFQSLRNINLLDLSGNIIRGLLSDFLKALHprvlNSLQYLSLRINEFCGFLPNfTMLPS 364
Cdd:PLN00113   67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTS----SSLRYLNLSNNNFTGSIPR-GSIPN 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 365 LKHLELSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHS 444
Cdd:PLN00113  142 LETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGY 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 445 NSLSGTIPQNLGQLSNLEYLDLHSNSLEGEVSeahfSKLINLKrldlsnnslslnlktdwvpsfQLDYIILGQCNL-GPL 523
Cdd:PLN00113  222 NNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIP----SSLGNLK---------------------NLQYLFLYQNKLsGPI 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 524 FPewlrtqtptlidiSFAGISDIVphwfwnnlspGMDLSGNKMMGEIPNLSLKFNMAPVISLKSNKFVGRIP---AFLFQ 600
Cdd:PLN00113  277 PP-------------SIFSLQKLI----------SLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPvalTSLPR 333

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 601 AEFLHLSSNDFS-----DLSGlceivNSPLETLDLSDNQLSGQLPDCWDSMLHLKILNLSNNYFFGDVPHSIGNLIHMES 675
Cdd:PLN00113  334 LQVLQLWSNKFSgeipkNLGK-----HNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRR 408

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 676 LVLRNNQFSGGLPFLF-NLTYLGVIDAMNNNLSGTIPS--WigsKIPYLTILNLKSNHFHGNLGRgLCNLKYIQILDISS 752
Cdd:PLN00113  409 VRLQDNSFSGELPSEFtKLPLVYFLDISNNNLQGRINSrkW---DMPSLQMLSLARNKFFGGLPD-SFGSKRLENLDLSR 484

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 753 NNVSGSIPTCIRNFNALTQtlfsghpnyetdifmvwkggerhitgqvmdlvrsIDLSCNHLSGKIPYEITQLVELIILNL 832
Cdd:PLN00113  485 NQFSGAVPRKLGSLSELMQ----------------------------------LKLSENKLSGEIPDELSSCKKLVSLDL 530

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1229768265 833 SRNELTGQIPDKIGRLQSLESLDLSRNHLSGPIPSHLSQVFRLGVLDLSYNNLSGKIPMGTQLQGFSTSSYEGNPYLCG 911
Cdd:PLN00113  531 SHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
259-486 4.39e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 106.17  E-value: 4.39e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 259 LINFTNIVHLNLAYNNLEGLSFDDFGNMTSLVSLDLSGTqvnfhslKSFQSLRNINLLDLSGNIIRGLLSDFLKalhprv 338
Cdd:COG4886    68 LLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELAN------ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 339 LNSLQYLSLRINEFCGFLPNFTMLPSLKHLELSDNMLNgTIPQNSGQLSNLEYLDLHSNSLSgNIPQNLGQLSNLKYLDL 418
Cdd:COG4886   135 LTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDL 212

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1229768265 419 GWNSLSgTIPQNLGQLSNLEYLDLHSNSLSgTIPqNLGQLSNLEYLDLHSNSLEGEVSEAHFSKLINL 486
Cdd:COG4886   213 SGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTL 277
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 289-490 1.29e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 54.67  E-value: 1.29e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 289 LVSLDLSGTQVNFHSLK----SFQSLRNINLLDLSGNIIRGLLSDFLKALHP-RVLNSLQYLSLRINEF----CGFLPNF 359
Cdd:cd00116    25 LQVLRLEGNTLGEEAAKalasALRPQPSLKELCLSLNETGRIPRGLQSLLQGlTKGCGLQELDLSDNALgpdgCGVLESL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 360 TMLPSLKHLELSDNMLNGTIPQNSGQ-----LSNLEYLDLHSNSLSGNIPQNLGQL----SNLKYLDLGWNSLSG----T 426
Cdd:cd00116   105 LRSSSLQELKLNNNGLGDRGLRLLAKglkdlPPALEKLVLGRNRLEGASCEALAKAlranRDLKELNLANNGIGDagirA 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1229768265 427 IPQNLGQLSNLEYLDLHSNS--------LSGTIPQNlgqlSNLEYLDLHSNSL--EG--EVSEAHFSKLINLKRLD 490
Cdd:cd00116   185 LAEGLKANCNLEVLDLNNNGltdegasaLAETLASL----KSLEVLNLGDNNLtdAGaaALASALLSPNISLLTLS 256
PLN03150 PLN03150
hypothetical protein; Provisional
 66-173 7.08e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.28  E-value: 7.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265  66 NNDCC-----NWSAVRCS-NKTEGHHVI---GIDLRGshdkyLKGEVGSSsLTQLSRLKYLDLSYNQFDRILLEDIGSLV 136
Cdd:PLN03150  393 NGDPCvpqqhPWSGADCQfDSTKGKWFIdglGLDNQG-----LRGFIPND-ISKLRHLQSINLSGNSIRGNIPPSLGSIT 466

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1229768265 137 NMNYLNLSYNWFKTALPPHLGNLSKLSVLDLGNNYWS 173
Cdd:PLN03150  467 SLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLS 503
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 41-78 3.42e-06

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 44.59  E-value: 3.42e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1229768265  41 ESERQALLSFQQRLTDEYGILSSWVNN--DCCNWSAVRCS 78
Cdd:pfam08263   2 NDDGQALLAFKSSLNDPPGALSSWNSSssDPCSWTGVTCD 41
LRR_8 pfam13855
Leucine rich repeat;
411-471 3.43e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 3.43e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1229768265 411 SNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSL 471
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 285-911 9.29e-78

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 274.42  E-value: 9.29e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 285 NMTSLVSLDLSGTQVNFHSLKSFQSLRNINLLDLSGNIIRGLLSDFLKALHprvlNSLQYLSLRINEFCGFLPNfTMLPS 364
Cdd:PLN00113   67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTS----SSLRYLNLSNNNFTGSIPR-GSIPN 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 365 LKHLELSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHS 444
Cdd:PLN00113  142 LETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGY 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 445 NSLSGTIPQNLGQLSNLEYLDLHSNSLEGEVSeahfSKLINLKrldlsnnslslnlktdwvpsfQLDYIILGQCNL-GPL 523
Cdd:PLN00113  222 NNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIP----SSLGNLK---------------------NLQYLFLYQNKLsGPI 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 524 FPewlrtqtptlidiSFAGISDIVphwfwnnlspGMDLSGNKMMGEIPNLSLKFNMAPVISLKSNKFVGRIP---AFLFQ 600
Cdd:PLN00113  277 PP-------------SIFSLQKLI----------SLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPvalTSLPR 333

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 601 AEFLHLSSNDFS-----DLSGlceivNSPLETLDLSDNQLSGQLPDCWDSMLHLKILNLSNNYFFGDVPHSIGNLIHMES 675
Cdd:PLN00113  334 LQVLQLWSNKFSgeipkNLGK-----HNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRR 408

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 676 LVLRNNQFSGGLPFLF-NLTYLGVIDAMNNNLSGTIPS--WigsKIPYLTILNLKSNHFHGNLGRgLCNLKYIQILDISS 752
Cdd:PLN00113  409 VRLQDNSFSGELPSEFtKLPLVYFLDISNNNLQGRINSrkW---DMPSLQMLSLARNKFFGGLPD-SFGSKRLENLDLSR 484

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 753 NNVSGSIPTCIRNFNALTQtlfsghpnyetdifmvwkggerhitgqvmdlvrsIDLSCNHLSGKIPYEITQLVELIILNL 832
Cdd:PLN00113  485 NQFSGAVPRKLGSLSELMQ----------------------------------LKLSENKLSGEIPDELSSCKKLVSLDL 530

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1229768265 833 SRNELTGQIPDKIGRLQSLESLDLSRNHLSGPIPSHLSQVFRLGVLDLSYNNLSGKIPMGTQLQGFSTSSYEGNPYLCG 911
Cdd:PLN00113  531 SHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 43-686 3.02e-49

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 189.67  E-value: 3.02e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265  43 ERQALLSFQQRLTDEYGILSSW-VNNDCCNWSAVRCSNKTeghHVIGIDLRGshdKYLKGEVgSSSLTQLSRLKYLDLSY 121
Cdd:PLN00113   30 ELELLLSFKSSINDPLKYLSNWnSSADVCLWQGITCNNSS---RVVSIDLSG---KNISGKI-SSAIFRLPYIQTINLSN 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 122 NQFDRILLEDIGSLV-NMNYLNLSYNWFKTALPPhlGNLSKLSVLDLGNNYWSSGNLRWLLSLSSLQHLdlsrgDFGGaN 200
Cdd:PLN00113  103 NQLSGPIPDDIFTTSsSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVL-----DLGG-N 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 201 DWVGVInqlpllqslslsdcnlpPPILSshsytnfsrflveldlslnldlnssiyhswliNFTNIVHLNLAYNNLEGLSF 280
Cdd:PLN00113  175 VLVGKI-----------------PNSLT--------------------------------NLTSLEFLTLASNQLVGQIP 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 281 DDFGNMTSLVSLDLSGTQVNFHSLKSFQSLRNINLLDLSGNIIRGLLSDFLKALhprvlNSLQYLSLRINEFCGFLPNFT 360
Cdd:PLN00113  206 RELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNL-----KNLQYLFLYQNKLSGPIPPSI 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 361 M-LPSLKHLELSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEY 439
Cdd:PLN00113  281 FsLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTV 360

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 440 LDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSLEGEVSEA-----------------------HFSKLINLKRLDLSNNSL 496
Cdd:PLN00113  361 LDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSlgacrslrrvrlqdnsfsgelpsEFTKLPLVYFLDISNNNL 440

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 497 SLNLKTDWVPSFQLDYIILGQCNLGPLFPEWLRTQTPTLIDISFAGISDIVPHWFwNNLSPGMD--LSGNKMMGEIPN-L 573
Cdd:PLN00113  441 QGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKL-GSLSELMQlkLSENKLSGEIPDeL 519

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 574 SLKFNMAPvISLKSNKFVGRIPAflfqaeflhlssnDFSDLSGLCEivnspletLDLSDNQLSGQLPDCWDSMLHLKILN 653
Cdd:PLN00113  520 SSCKKLVS-LDLSHNQLSGQIPA-------------SFSEMPVLSQ--------LDLSQNQLSGEIPKNLGNVESLVQVN 577

                         650       660       670
                  ....*....|....*....|....*....|...
gi 1229768265 654 LSNNYFFGDVPHSIGNLIHMESLVLRNNQFSGG 686
Cdd:PLN00113  578 ISHNHLHGSLPSTGAFLAINASAVAGNIDLCGG 610
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 99-689 7.80e-32

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 134.21  E-value: 7.80e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265  99 LKGEVgSSSLTQLSRLKYLDLSYNQFDRILLEDIGSLVNMNYLNLSYNWFKTALPPHLGNLSKLSVLDLGNNYWSSgnlr 178
Cdd:PLN00113  200 LVGQI-PRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSG---- 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 179 wllslsslqhldlsrgdfggandwvgvinqlpllqslslsdcNLPPPILsshsytnfsrflveldlslnldlnssiyhsw 258
Cdd:PLN00113  275 ------------------------------------------PIPPSIF------------------------------- 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 259 linftnivhlnlaynnleglsfddfgNMTSLVSLDLSGtqvNFhslksfqslrninlldLSGNIIRGLLSdflkalhprv 338
Cdd:PLN00113  282 --------------------------SLQKLISLDLSD---NS----------------LSGEIPELVIQ---------- 306

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 339 LNSLQYLSLRINEFCGFLP-NFTMLPSLKHLELSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLD 417
Cdd:PLN00113  307 LQNLEILHLFSNNFTGKIPvALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLI 386

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 418 LGWNSLSGTIPQNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSLEGEvseahfsklINLKRLDlsnnsls 497
Cdd:PLN00113  387 LFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGR---------INSRKWD------- 450

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 498 lnlktdwVPSFQldyiilgqcnlgplfpewlrtqtptLIDISFAGISDIVPHWFWNNLSPGMDLSGNKMMGEIPNLSLKF 577
Cdd:PLN00113  451 -------MPSLQ-------------------------MLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSL 498

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 578 NMAPVISLKSNKFVGRIPaflfqaeflhlssndfSDLSGLCEIVNspletLDLSDNQLSGQLPDCWDSMLHLKILNLSNN 657
Cdd:PLN00113  499 SELMQLKLSENKLSGEIP----------------DELSSCKKLVS-----LDLSHNQLSGQIPASFSEMPVLSQLDLSQN 557

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 1229768265 658 YFFGDVPHSIGNLihmESLV---LRNNQFSGGLPF 689
Cdd:PLN00113  558 QLSGEIPKNLGNV---ESLVqvnISHNHLHGSLPS 589
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
259-486 4.39e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 106.17  E-value: 4.39e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 259 LINFTNIVHLNLAYNNLEGLSFDDFGNMTSLVSLDLSGTqvnfhslKSFQSLRNINLLDLSGNIIRGLLSDFLKalhprv 338
Cdd:COG4886    68 LLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELAN------ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 339 LNSLQYLSLRINEFCGFLPNFTMLPSLKHLELSDNMLNgTIPQNSGQLSNLEYLDLHSNSLSgNIPQNLGQLSNLKYLDL 418
Cdd:COG4886   135 LTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDL 212

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1229768265 419 GWNSLSgTIPQNLGQLSNLEYLDLHSNSLSgTIPqNLGQLSNLEYLDLHSNSLEGEVSEAHFSKLINL 486
Cdd:COG4886   213 SGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTL 277
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
226-490 1.01e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 101.93  E-value: 1.01e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 226 ILSSHSYTNFSRFLVELDLSLNLDLNSSIYHSWLINFTNIVHLNLAYNNLEGLSFDDFGNMTSLVSLDLSGTQVNFHSLK 305
Cdd:COG4886    11 KLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 306 SFQSLRNINLLDLSGNIIRGLLSDflkalhprvlnsLQYLSLRINEFCGFLPNFTMLPSLKHLELSDNMLNgTIPQNSGQ 385
Cdd:COG4886    91 DLGDLTNLTELDLSGNEELSNLTN------------LESLDLSGNQLTDLPEELANLTNLKELDLSNNQLT-DLPEPLGN 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 386 LSNLEYLDLHSNSLSgNIPQNLGQLSNLKYLDLGWNSLSgTIPQNLGQLSNLEYLDLHSNSLSgTIPQNLGQLSNLEYLD 465
Cdd:COG4886   158 LTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLD 234

                         250       260
                  ....*....|....*....|....*
gi 1229768265 466 LHSNSLEgevSEAHFSKLINLKRLD 490
Cdd:COG4886   235 LSNNQLT---DLPELGNLTNLEELD 256
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
259-528 4.06e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 97.31  E-value: 4.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 259 LINFTNIVHLNLAYNNLEGLsFDDFGNMTSLVSLDLSGTQvnFHSL-KSFQSLRNINLLDLSGNIIRGLLSDFLKalhpr 337
Cdd:COG4886   109 LSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQ--LTDLpEPLGNLTNLKSLDLSNNQLTDLPEELGN----- 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 338 vLNSLQYLSLRINEFCGFLPNFTMLPSLKHLELSDNMLNgTIPQNSGQLSNLEYLDLHSNSLSgNIPqNLGQLSNLKYLD 417
Cdd:COG4886   181 -LTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELD 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 418 LGWNSLSgTIPqNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSLEGEVSEAHFSKLINLKRLDLSNNSLS 497
Cdd:COG4886   257 LSNNQLT-DLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLL 334

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1229768265 498 LNLKTDWVPSFQLDYIILGQCNLGPLFPEWL 528
Cdd:COG4886   335 VTLTTLALSLSLLALLTLLLLLNLLSLLLTL 365
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
254-490 8.81e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 96.16  E-value: 8.81e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 254 IYHSWLINFTNIVHLNLAYNNLEGLSFDDFGNMTSLVSLDLSGTQVNFHSLKSFQSLRNINLLDLSGNIIRGLLSDFLKA 333
Cdd:COG4886     4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 334 LHPRVLNSLQYLSLRINEFCGFLPNFTMLPSLKHLELSDNMLNgTIPQNSGQLSNLEYLDLHSNSLSgNIPQNLGQLSNL 413
Cdd:COG4886    84 LLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1229768265 414 KYLDLGWNSLSgTIPQNLGQLSNLEYLDLHSNSLSgTIPQNLGQLSNLEYLDLHSNSLEgEVSEAhFSKLINLKRLD 490
Cdd:COG4886   162 KSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT-DLPEP-LANLTNLETLD 234
PLN03150 PLN03150
hypothetical protein; Provisional
 368-456 3.52e-17

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 86.41  E-value: 3.52e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 368 LELSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHSNSL 447
Cdd:PLN03150  423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502


                  ....*....
gi 1229768265 448 SGTIPQNLG 456
Cdd:PLN03150  503 SGRVPAALG 511
PLN03150 PLN03150
hypothetical protein; Provisional
 802-917 8.34e-16

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 81.79  E-value: 8.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 802 LVRSIDLSCNHLSGKIPYEITQLVELIILNLSRNELTGQIPDKIGRLQSLESLDLSRNHLSGPIPSHLSQVFRLGVLDLS 881
Cdd:PLN03150  419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLN 498

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1229768265 882 YNNLSGKIP--MGTQLQGFSTSSYEGNPYLCGDP-LKKC 917
Cdd:PLN03150  499 GNSLSGRVPaaLGGRLLHRASFNFTDNAGLCGIPgLRAC 537
PLN03150 PLN03150
hypothetical protein; Provisional
 392-478 1.38e-15

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 81.40  E-value: 1.38e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 392 LDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSL 471
Cdd:PLN03150  423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502


                  ....*..
gi 1229768265 472 EGEVSEA 478
Cdd:PLN03150  503 SGRVPAA 509
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
258-517 1.76e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 79.98  E-value: 1.76e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 258 WLINFTNIVHLNLAYNNLEGLSfDDFGNMTSLVSLDLSGTQVNfhSL-KSFQSLRNINLLDLSGNiirgLLSDFLKALhp 336
Cdd:COG4886   131 ELANLTNLKELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLT--DLpEELGNLTNLKELDLSNN----QITDLPEPL-- 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 337 RVLNSLQYLSLRINEFCGFLPNFTMLPSLKHLELSDNMLNgTIPqNSGQLSNLEYLDLHSNSLSgNIPqNLGQLSNLKYL 416
Cdd:COG4886   202 GNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLT-DLP-PLANLTNLKTL 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 417 DLGWNSLSGTIPQNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSLEGEVSEAHFSKLINLKRLDLSNNSL 496
Cdd:COG4886   278 DLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLN 357

                         250       260
                  ....*....|....*....|.
gi 1229768265 497 SLNLKTDWVPSFQLDYIILGQ 517
Cdd:COG4886   358 LLSLLLTLLLTLGLLGLLEAT 378
PLN03150 PLN03150
hypothetical protein; Provisional
 354-432 2.72e-15

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 80.24  E-value: 2.72e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 354 GFLPNftMLPSLKHLE---LSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQN 430
Cdd:PLN03150  432 GFIPN--DISKLRHLQsinLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509


                  ..
gi 1229768265 431 LG 432
Cdd:PLN03150  510 LG 511
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
625-890 7.56e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.05  E-value: 7.56e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 625 LETLDLSDNQLSGQLPDcwdsmlhLKILNLSNNYFfGDVPHSIGNLIHMESLVLRNNQFSGGLPFLFNLTYLGVIDAMNN 704
Cdd:COG4886    98 LTELDLSGNEELSNLTN-------LESLDLSGNQL-TDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNN 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 705 NLSgTIPSWIGsKIPYLTILNLKSNHFHgNLGRGLCNLKYIQILDISSNNVSgSIPTCIRNFNALTqtlfsghpnyetdi 784
Cdd:COG4886   170 QLT-DLPEELG-NLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLE-------------- 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 785 fmvwkggerhitgqvmdlvrSIDLSCNHLSgKIPyEITQLVELIILNLSRNELTGqIPdKIGRLQSLESLDLSRNHLSGP 864
Cdd:COG4886   232 --------------------TLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTD-LP-PLANLTNLKTLDLSNNQLTDL 287

                         250       260
                  ....*....|....*....|....*.
gi 1229768265 865 IPSHLSQVFRLGVLDLSYNNLSGKIP 890
Cdd:COG4886   288 KLKELELLLGLNSLLLLLLLLNLLEL 313
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
575-942 3.09e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.13  E-value: 3.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 575 LKFNMAPVISLKSNKFVGRIPAFLFQAEFLHLSSNDFSDLSGLCEIVNSPLETLDLSDNQLSGQLPDCWDSMLHLKILNL 654
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 655 SNNYFFGDvPHSIGNLIHMESLVLRNNQFsgglpfLFNLTYLGVIDAMNNNLSgTIPSWIGsKIPYLTILNLKSNHFHgN 734
Cdd:COG4886    81 LLSLLLLG-LTDLGDLTNLTELDLSGNEE------LSNLTNLESLDLSGNQLT-DLPEELA-NLTNLKELDLSNNQLT-D 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 735 LGRGLCNLKYIQILDISSNNVSgSIPTCIRNFNALtqtlfsghpnyetdifmvwkggerhitgqvmdlvRSIDLSCNHLS 814
Cdd:COG4886   151 LPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNL----------------------------------KELDLSNNQIT 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 815 gKIPYEITQLVELIILNLSRNELTgQIPDKIGRLQSLESLDLSRNHLSgPIPShLSQVFRLGVLDLSYNNLSGkIPMGTQ 894
Cdd:COG4886   196 -DLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLPE-LGNLTNLEELDLSNNQLTD-LPPLAN 270

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1229768265 895 LQGFSTSSYEGNPyLCGDPLKKCSEDINQEPNINNVHVENENEDEDKL 942
Cdd:COG4886   271 LTNLKTLDLSNNQ-LTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
PLN03150 PLN03150
hypothetical protein; Provisional
 628-740 2.89e-13

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 73.70  E-value: 2.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 628 LDLSDNQLSGQLPDCWDSMLHLKILNLSNNYFFGDVPHSIGNLIHMESLVLRNNQFSGGLP-FLFNLTYLGVIDAMNNNL 706
Cdd:PLN03150  423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPeSLGQLTSLRILNLNGNSL 502

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1229768265 707 SGTIPSWIGSKIPYLTILNLKSNhfhgnlgRGLC 740
Cdd:PLN03150  503 SGRVPAALGGRLLHRASFNFTDN-------AGLC 529
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
90-511 3.00e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.04  E-value: 3.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265  90 DLRGSHDKYLKGEVGSSSLTQLSRLKYLDLSYNqfdrillEDIGSLVNMNYLNLSYNWFkTALPPHLGNLSKLSVLDLGN 169
Cdd:COG4886    74 LLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQL-TDLPEELANLTNLKELDLSN 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 170 NYWSSgnlrwllslsslqhldlsrgdfggandwvgvinqlpllqslslsdcnLPPPILsshsytnfsrflveldlslnld 249
Cdd:COG4886   146 NQLTD-----------------------------------------------LPEPLG---------------------- 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 250 lnssiyhswliNFTNIVHLNLAYNNLEGLSfDDFGNMTSLVSLDLSGTQVNFHSlKSFQSLRNINLLDLSGNIIRGLLSD 329
Cdd:COG4886   157 -----------NLTNLKSLDLSNNQLTDLP-EELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 330 FLKalhprvLNSLQYLSLRINEFCGfLPNFTMLPSLKHLELSDNMLNgTIPqNSGQLSNLEYLDLHSNSLSGNIPQNLGQ 409
Cdd:COG4886   224 LAN------LTNLETLDLSNNQLTD-LPELGNLTNLEELDLSNNQLT-DLP-PLANLTNLKTLDLSNNQLTDLKLKELEL 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 410 LSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSLEGEVSEAHFSKLINLKRL 489
Cdd:COG4886   295 LLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGL 374

                         410       420
                  ....*....|....*....|..
gi 1229768265 490 DLSNNSLSLNLKTDWVPSFQLD 511
Cdd:COG4886   375 LEATLLTLALLLLTLLLLLLTT 396
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
534-869 1.05e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.12  E-value: 1.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 534 TLIDISFAGISDIVPHWFWNNLSPGMDLSGNKMMGEIPNLSLKFNMAPVISLKSNKFVGRIPAFLFQAEFLHLSSNDFSD 613
Cdd:COG4886    23 TLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELD 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 614 LSGLCEIVN-SPLETLDLSDNQLSgQLPDCWDSMLHLKILNLSNNYFfGDVPHSIGNLIHMESLVLRNNQFSGGLPFLFN 692
Cdd:COG4886   103 LSGNEELSNlTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQL-TDLPEPLGNLTNLKSLDLSNNQLTDLPEELGN 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 693 LTYLGVIDAMNNNLSgTIPSWIGsKIPYLTILNLKSNHFHgNLGRGLCNLKYIQILDISSNNVSgSIPtCIRNFNALTQT 772
Cdd:COG4886   181 LTNLKELDLSNNQIT-DLPEPLG-NLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEEL 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 773 LFSGhpNYETDIFMVWKggerhitgqvMDLVRSIDLSCNHLSGKIPYEITQLVELIILNLSRNELTGQIPDKIGRLQSLE 852
Cdd:COG4886   256 DLSN--NQLTDLPPLAN----------LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTL 323

                         330
                  ....*....|....*..
gi 1229768265 853 SLDLSRNHLSGPIPSHL 869
Cdd:COG4886   324 LLLLLLLKGLLVTLTTL 340
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
582-859 7.04e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 65.34  E-value: 7.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 582 VISLKSNKFvGRIPAFLFQA---EFLHLSSNDFSDLSGlcEIVNSP-LETLDLSDNQLSgQLPDCWDSMLHLKILNLSNN 657
Cdd:COG4886   140 ELDLSNNQL-TDLPEPLGNLtnlKSLDLSNNQLTDLPE--ELGNLTnLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGN 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 658 YFfGDVPHSIGNLIHMESLVLRNNQFSGgLPFLFNLTYLGVIDAMNNNLSgTIPSwiGSKIPYLTILNLKSNHFHGNLGR 737
Cdd:COG4886   216 QL-TDLPEPLANLTNLETLDLSNNQLTD-LPELGNLTNLEELDLSNNQLT-DLPP--LANLTNLKTLDLSNNQLTDLKLK 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 738 GLCNLKYIQILDISSNNVSGSIPTCIRNFNALTQTLFSGHPNYETDIFMVWKGGERHITGQVMDLVRSIDLSCNHLSGKI 817
Cdd:COG4886   291 ELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLG 370

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1229768265 818 PYEITQLVELIILNLSRNELTGQIPDKIGRLQSLESLDLSRN 859
Cdd:COG4886   371 LLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVN 412
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
389-838 1.79e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 58.02  E-value: 1.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 389 LEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHS 468
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 469 NSLEGEVSEAHFSKLINLKRLDLSNNSLSLNLKtdwvpsfQLDYIILGQCNLGPLFPEWLRTQTPTLIDISFAGISDIvp 548
Cdd:COG4886    81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNLT-------NLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDL-- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 549 hwfwnnlspgmdlsgNKMMGEIPNLSlkfnmapVISLKSNKfVGRIPAFLFQA---EFLHLSSNDFSDLSG-LCEIVNsp 624
Cdd:COG4886   152 ---------------PEPLGNLTNLK-------SLDLSNNQ-LTDLPEELGNLtnlKELDLSNNQITDLPEpLGNLTN-- 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 625 LETLDLSDNQLSgQLPDCWDSMLHLKILNLSNNYfFGDVPhSIGNLIHMESLVLRNNQFSgGLPFLFNLTYLGVIDAMNN 704
Cdd:COG4886   207 LEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQ-LTDLP-ELGNLTNLEELDLSNNQLT-DLPPLANLTNLKTLDLSNN 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 705 NLSGTipsWIGSKIPYLTILNLKSNHFHGNLGRGLCNLKYIQILDISSNNVSGSIPTCIRNFNALTQTLFSGHPNYETDI 784
Cdd:COG4886   283 QLTDL---KLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLL 359

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1229768265 785 FMVWKGGERHITGQVMDLVRSIDLSCNHLSGKIPYEITQLVELIILNLSRNELT 838
Cdd:COG4886   360 SLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNT 413
PLN03150 PLN03150
hypothetical protein; Provisional
 549-690 8.69e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 55.98  E-value: 8.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 549 HWFWNnlspGMDLSGNKMMGEIPNLSLKFNMAPVISLKSNKFVGRIPAflfqaeflhlssnDFSDLSGLceivnsplETL 628
Cdd:PLN03150  417 KWFID----GLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPP-------------SLGSITSL--------EVL 471

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1229768265 629 DLSDNQLSGQLPDCWDSMLHLKILNLSNNYFFGDVPHSIGN-LIHMESLVLRNNQFSGGLPFL 690
Cdd:PLN03150  472 DLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALGGrLLHRASFNFTDNAGLCGIPGL 534
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 289-490 1.29e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 54.67  E-value: 1.29e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 289 LVSLDLSGTQVNFHSLK----SFQSLRNINLLDLSGNIIRGLLSDFLKALHP-RVLNSLQYLSLRINEF----CGFLPNF 359
Cdd:cd00116    25 LQVLRLEGNTLGEEAAKalasALRPQPSLKELCLSLNETGRIPRGLQSLLQGlTKGCGLQELDLSDNALgpdgCGVLESL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 360 TMLPSLKHLELSDNMLNGTIPQNSGQ-----LSNLEYLDLHSNSLSGNIPQNLGQL----SNLKYLDLGWNSLSG----T 426
Cdd:cd00116   105 LRSSSLQELKLNNNGLGDRGLRLLAKglkdlPPALEKLVLGRNRLEGASCEALAKAlranRDLKELNLANNGIGDagirA 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1229768265 427 IPQNLGQLSNLEYLDLHSNS--------LSGTIPQNlgqlSNLEYLDLHSNSL--EG--EVSEAHFSKLINLKRLD 490
Cdd:cd00116   185 LAEGLKANCNLEVLDLNNNGltdegasaLAETLASL----KSLEVLNLGDNNLtdAGaaALASALLSPNISLLTLS 256
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 356-490 4.32e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.71  E-value: 4.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 356 LPNFTMLPSLKHLELSDNMLNgTIPqNSGQLSNLEYLDLHSNSLSgNIpQNLGQLSNLKYLDLGWNSLSgtIPQNLGQLS 435
Cdd:cd21340    17 IDNLSLCKNLKVLYLYDNKIT-KIE-NLEFLTNLTHLYLQNNQIE-KI-ENLENLVNLKKLYLGGNRIS--VVEGLENLT 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 436 NLEYLDL--------------------HSNSL-----SG---TIPQNLGQLSNLEYLDLHSNSLEG-EVSEAHFSKLINL 486
Cdd:cd21340    91 NLEELHIenqrlppgekltfdprslaaLSNSLrvlniSGnniDSLEPLAPLRNLEQLDASNNQISDlEELLDLLSSWPSL 170


                  ....
gi 1229768265 487 KRLD 490
Cdd:cd21340   171 RELD 174
PLN03150 PLN03150
hypothetical protein; Provisional
 66-173 7.08e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.28  E-value: 7.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265  66 NNDCC-----NWSAVRCS-NKTEGHHVI---GIDLRGshdkyLKGEVGSSsLTQLSRLKYLDLSYNQFDRILLEDIGSLV 136
Cdd:PLN03150  393 NGDPCvpqqhPWSGADCQfDSTKGKWFIdglGLDNQG-----LRGFIPND-ISKLRHLQSINLSGNSIRGNIPPSLGSIT 466

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1229768265 137 NMNYLNLSYNWFKTALPPHLGNLSKLSVLDLGNNYWS 173
Cdd:PLN03150  467 SLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLS 503
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 41-78 3.42e-06

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 44.59  E-value: 3.42e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1229768265  41 ESERQALLSFQQRLTDEYGILSSWVNN--DCCNWSAVRCS 78
Cdd:pfam08263   2 NDDGQALLAFKSSLNDPPGALSSWNSSssDPCSWTGVTCD 41
LRR_8 pfam13855
Leucine rich repeat;
411-471 3.43e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 3.43e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1229768265 411 SNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSL 471
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
387-447 4.42e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.82  E-value: 4.42e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1229768265 387 SNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSLSGTIPQNLGQLSNLEYLDLHSNSL 447
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 307-491 2.03e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 47.74  E-value: 2.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 307 FQSLRNINLLDLSGNIIRGL-LSDFLKALHPRvlNSLQYLSLRINEFCGFLPN-------FTMLPSLKHLELSDNMLNGT 378
Cdd:cd00116    19 LPKLLCLQVLRLEGNTLGEEaAKALASALRPQ--PSLKELCLSLNETGRIPRGlqsllqgLTKGCGLQELDLSDNALGPD 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 379 IP---QNSGQLSNLEYLDLHSNSLSGNIPQNLGQ-----LSNLKYLDLGWNSLSGTIPQNLGQL----SNLEYLDLHSNS 446
Cdd:cd00116    97 GCgvlESLLRSSSLQELKLNNNGLGDRGLRLLAKglkdlPPALEKLVLGRNRLEGASCEALAKAlranRDLKELNLANNG 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1229768265 447 LSG----TIPQNLGQLSNLEYLDLHSNSL--EGEVSEAH-FSKLINLKRLDL 491
Cdd:cd00116   177 IGDagirALAEGLKANCNLEVLDLNNNGLtdEGASALAEtLASLKSLEVLNL 228
PLN03150 PLN03150
hypothetical protein; Provisional
 698-776 2.42e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.27  E-value: 2.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 698 VIDAM---NNNLSGTIPSWIgSKIPYLTILNLKSNHFHGNLGRGLCNLKYIQILDISSNNVSGSIPTCIRNFNALTQTLF 774
Cdd:PLN03150  419 FIDGLgldNQGLRGFIPNDI-SKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNL 497


                  ..
gi 1229768265 775 SG 776
Cdd:PLN03150  498 NG 499
LRR_8 pfam13855
Leucine rich repeat;
363-423 6.85e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.36  E-value: 6.85e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1229768265 363 PSLKHLELSDNMLNGTIPQNSGQLSNLEYLDLHSNSLSGNIPQNLGQLSNLKYLDLGWNSL 423
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
435-490 2.71e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.71e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1229768265 435 SNLEYLDLHSNSLSGTIPQNLGQLSNLEYLDLHSNSLEGeVSEAHFSKLINLKRLD 490
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT-LSPGAFSGLPSLRYLD 55
LRR_8 pfam13855
Leucine rich repeat;
263-321 2.88e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.88e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1229768265 263 TNIVHLNLAYNNLEGLSFDDFGNMTSLVSLDLSGTQVNFHSLKSFQSLRNINLLDLSGN 321
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
LRR_8 pfam13855
Leucine rich repeat;
803-861 4.99e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 4.99e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1229768265 803 VRSIDLSCNHLSGKIPYEITQLVELIILNLSRNELTGQIPDKIGRLQSLESLDLSRNHL 861
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 84-157 5.87e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 43.65  E-value: 5.87e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1229768265  84 HHVIGIDLRGShdkYLKGEVgSSSLTQLSRLKYLDLSYNQFDRILLEDIGSLVNMNYLNLSYNWFKTALPPHLG 157
Cdd:PLN03150  442 RHLQSINLSGN---SIRGNI-PPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALG 511
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 259-418 2.03e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.92  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 259 LINFTNIVHLNLAYNNLEglSFDDFGNMTSLVSLDLSGTQVNfhSLKSFQSLRNINLLDLSGNIIR---GLLS-DFLKAL 334
Cdd:cd21340    20 LSLCKNLKVLYLYDNKIT--KIENLEFLTNLTHLYLQNNQIE--KIENLENLVNLKKLYLGGNRISvveGLENlTNLEEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1229768265 335 HprvlnsLQYLSLRINEFCGFLPN--FTMLPSLKHLELSDNMLngTIPQNSGQLSNLEYLDLHSNSLS--GNIPQNLGQL 410
Cdd:cd21340    96 H------IENQRLPPGEKLTFDPRslAALSNSLRVLNISGNNI--DSLEPLAPLRNLEQLDASNNQISdlEELLDLLSSW 167


                  ....*...
gi 1229768265 411 SNLKYLDL 418
Cdd:cd21340   168 PSLRELDL 175
PLN03150 PLN03150
hypothetical protein; Provisional
 268-325 5.32e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.57  E-value: 5.32e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1229768265 268 LNLAYNNLEGLSFDDFGNMTSLVSLDLSGTQVNFHSLKSFQSLRNINLLDLSGNIIRG 325
Cdd:PLN03150  447 INLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSG 504
LRR_8 pfam13855
Leucine rich repeat;
829-885 8.01e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 8.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1229768265 829 ILNLSRNELTGQIPDKIGRLQSLESLDLSRNHLSGPIPSHLSQVFRLGVLDLSYNNL 885
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
625-683 8.17e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 8.17e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1229768265 625 LETLDLSDNQLSGQLPDCWDSMLHLKILNLSNNYFFGDVPHSIGNLIHMESLVLRNNQF 683
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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