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Conserved domains on  [gi|122937285|ref|NP_001073913|]
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immunoglobulin superfamily member 5 [Homo sapiens]

Protein Classification

immunoglobulin domain-containing protein( domain architecture ID 12209963)

immunoglobulin (Ig) domain-containing protein with one or more Ig domains, which adopt a fold comprised of a sandwich of two beta sheets and may function in cell adhesion and/or pattern recognition

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 45-138 5.11e-08

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


:

Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 50.20  E-value: 5.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937285    45 PQNARVLKGSQARFNCTVSQGWKLIMWalsdmvvLSVRPMEPIITNDRFTSQRYdqggNFTSEMIIHNVEPSDSGNIRCS 124
Cdd:smart00410   1 PPSVTVKEGESVTLSCEASGSPPPEVT-------WYKQGGKLLAESGRFSVSRS----GSTSTLTISNVTPEDSGTYTCA 69

                           90
                   ....*....|....*.
gi 122937285   125 LQNSR--LHGSAYLTV 138
Cdd:smart00410  70 ATNSSgsASSGTTLTV 85
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 143-218 5.75e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


:

Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 35.62  E-value: 5.75e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 122937285  143 ELFIPSVNLVVAENEPCEVTCLPSHWTRlPDISWELGLLVSHSSYYFVPEPSDLQSAVSILALTPQSNGTLTCVAT 218
Cdd:pfam13927   3 VITVSPSSVTVREGETVTLTCEATGSPP-PTITWYKNGEPISSGSTRSRSLSGSNSTLTISNVTRSDAGTYTCVAS 77
 
Name Accession Description Interval E-value
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 45-138 5.11e-08

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 50.20  E-value: 5.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937285    45 PQNARVLKGSQARFNCTVSQGWKLIMWalsdmvvLSVRPMEPIITNDRFTSQRYdqggNFTSEMIIHNVEPSDSGNIRCS 124
Cdd:smart00410   1 PPSVTVKEGESVTLSCEASGSPPPEVT-------WYKQGGKLLAESGRFSVSRS----GSTSTLTISNVTPEDSGTYTCA 69

                           90
                   ....*....|....*.
gi 122937285   125 LQNSR--LHGSAYLTV 138
Cdd:smart00410  70 ATNSSgsASSGTTLTV 85
I-set pfam07679
Immunoglobulin I-set domain;
45-128 3.07e-05

Immunoglobulin I-set domain;


Pssm-ID: 400151 [Multi-domain]  Cd Length: 90  Bit Score: 42.24  E-value: 3.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937285   45 PQNARVLKGSQARFNCTVSqGWKL--IMWALSDmvvlsvrpmEPIITNDRFtSQRYDQGgnfTSEMIIHNVEPSDSGNIR 122
Cdd:pfam07679   7 PKDVEVQEGESARFTCTVT-GTPDpeVSWFKDG---------QPLRSSDRF-KVTYEGG---TYTLTISNVQPDDSGKYT 72


                  ....*.
gi 122937285  123 CSLQNS 128
Cdd:pfam07679  73 CVATNS 78
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 143-218 5.75e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 35.62  E-value: 5.75e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 122937285  143 ELFIPSVNLVVAENEPCEVTCLPSHWTRlPDISWELGLLVSHSSYYFVPEPSDLQSAVSILALTPQSNGTLTCVAT 218
Cdd:pfam13927   3 VITVSPSSVTVREGETVTLTCEATGSPP-PTITWYKNGEPISSGSTRSRSLSGSNSTLTISNVTRSDAGTYTCVAS 77
 
Name Accession Description Interval E-value
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 45-138 5.11e-08

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 50.20  E-value: 5.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937285    45 PQNARVLKGSQARFNCTVSQGWKLIMWalsdmvvLSVRPMEPIITNDRFTSQRYdqggNFTSEMIIHNVEPSDSGNIRCS 124
Cdd:smart00410   1 PPSVTVKEGESVTLSCEASGSPPPEVT-------WYKQGGKLLAESGRFSVSRS----GSTSTLTISNVTPEDSGTYTCA 69

                           90
                   ....*....|....*.
gi 122937285   125 LQNSR--LHGSAYLTV 138
Cdd:smart00410  70 ATNSSgsASSGTTLTV 85
I-set pfam07679
Immunoglobulin I-set domain;
45-128 3.07e-05

Immunoglobulin I-set domain;


Pssm-ID: 400151 [Multi-domain]  Cd Length: 90  Bit Score: 42.24  E-value: 3.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937285   45 PQNARVLKGSQARFNCTVSqGWKL--IMWALSDmvvlsvrpmEPIITNDRFtSQRYDQGgnfTSEMIIHNVEPSDSGNIR 122
Cdd:pfam07679   7 PKDVEVQEGESARFTCTVT-GTPDpeVSWFKDG---------QPLRSSDRF-KVTYEGG---TYTLTISNVQPDDSGKYT 72


                  ....*.
gi 122937285  123 CSLQNS 128
Cdd:pfam07679  73 CVATNS 78
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 143-218 5.75e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 35.62  E-value: 5.75e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 122937285  143 ELFIPSVNLVVAENEPCEVTCLPSHWTRlPDISWELGLLVSHSSYYFVPEPSDLQSAVSILALTPQSNGTLTCVAT 218
Cdd:pfam13927   3 VITVSPSSVTVREGETVTLTCEATGSPP-PTITWYKNGEPISSGSTRSRSLSGSNSTLTISNVTRSDAGTYTCVAS 77
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 45-127 6.40e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 35.23  E-value: 6.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937285   45 PQNARVLKGSQARFNCTVSQGWK-LIMWALSDMVVLSVRpmepiitndrftsQRYDQGGNFTSEMIIHNVEPSDSGNIRC 123
Cdd:pfam13927   8 PSSVTVREGETVTLTCEATGSPPpTITWYKNGEPISSGS-------------TRSRSLSGSNSTLTISNVTRSDAGTYTC 74


                  ....
gi 122937285  124 SLQN 127
Cdd:pfam13927  75 VASN 78
ig pfam00047
Immunoglobulin domain; Members of the immunoglobulin superfamily are found in hundreds of ...
 146-217 9.76e-03

Immunoglobulin domain; Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. Examples include antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-protein and protein-ligand interactions.


Pssm-ID: 395002  Cd Length: 86  Bit Score: 35.25  E-value: 9.76e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 122937285  146 IPSVNLVVAENEPCEVTCLPSHWTRLPDISWELGLLVS-HSSYYFVPEPSDLQSAVSILALTPQSNGTLTCVA 217
Cdd:pfam00047   1 SAPPTVTVLEGDSATLTCSASTGSPGPDVTWSKEGGTLiESLKVKHDNGRTTQSSLLISNVTKEDAGTYTCVV 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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