|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
2-357 |
7.77e-83 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 255.75 E-value: 7.77e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 2 NIVIVIDSLVGGGAEKVMLTLAQEMVLKDHNVTILSLAQNIEYDIPTTLNVESLFSgratKVDRFWQIKKNIRVLETWFE 81
Cdd:cd03811 1 KILFVIPSLSGGGAERVLLNLANALDKRGYDVTLVLLRDEGDLDKQLNGDVKLIRL----LIRVLKLIKLGLLKAILKLK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 82 QKLRQLgSIDIVLSNLDRSNN---LLAQSKIKnTHFVVHNSVNAELARQKKLGPLSYLYLKkskqnlnGKSLICVSKGVE 158
Cdd:cd03811 77 RILKRA-KPDVVISFLGFATYivaKLAAARSK-VIAWIHSSLSKLYYLKKKLLLKLKLYKK-------ADKIVCVSKGIK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 159 EEIQQGSLITPSAITTIYNPFNFKTINDKANEVNTNIP-DSPYLIHVGRLAKQKRHDILFSAFAKLDKKY---KLVLLCN 234
Cdd:cd03811 148 EDLIRLGPSPPEKIEVIYNPIDIDRIRALAKEPILNEPeDGPVILAVGRLDPQKGHDLLIEAFAKLRKKYpdvKLVILGD 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 235 --KKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPhGPSEILTGELS 312
Cdd:cd03811 228 gpLREELEKLAKELGLAERVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCP-GPREILDDGEN 306
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1222442790 313 KYLVPIGQGELLALAVKQVLADNPNVTNAAILEKVCADRVTEQYL 357
Cdd:cd03811 307 GLLVPDGDAAALAGILAALLQKKLDAALRERLAKAQEAVFREYTI 351
|
|
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
3-356 |
1.07e-54 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 183.21 E-value: 1.07e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 3 IVIVIDSL-VGGGAEKVMLTLAQEMVLKDHNVTILSLAQNIE---YDIPTTLNVESLFSGRATKVDRFWQIKKNIRVLEt 78
Cdd:cd03820 2 IAIVIPSIsNAGGAERVAINLANHLAKKGYDVTIISLDSAEKppfYELDDNIKIKNLGDRKYSHFKLLLKYFKKVRRLR- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 79 wfeqKLRQLGSIDIVLSNLDRSNNLLAqsKIK-NTHFVV--HNSVNAELARQKKLGPLSYLYLKKSKqnlngksLICVSK 155
Cdd:cd03820 81 ----KYLKNNKPDVVISFRTSLLTFLA--LIGlKSKLIVweHNNYEAYNKGLRRLLLRRLLYKRADK-------IVVLTE 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 156 GVEEEIQQGSLITpsaITTIYNPFNFKtindkaNEVNTNIPDSPYLIHVGRLAKQKRHDILFSAFAKLDKKY---KLVLL 232
Cdd:cd03820 148 ADKLKKYKQPNSN---VVVIPNPLSFP------SEEPSTNLKSKRILAVGRLTYQKGFDLLIEAWALIAKKHpdwKLRIY 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 233 --CNKKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPHGPSEILTGE 310
Cdd:cd03820 219 gdGPEREELEKLIDKLGLEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPTGPSEIIEDG 298
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1222442790 311 LSKYLVPIGQGELLALAVkQVLADNPNV----TNAAI--LEKVCADRVTEQY 356
Cdd:cd03820 299 ENGLLVPNGDVDALAEAL-LRLMEDEELrkkmGKNARknAERFSIEKIIKQW 349
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
2-334 |
3.00e-32 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 124.19 E-value: 3.00e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 2 NIVIVIDSL--VGGGAEKVMLTLAQEMVLKDHNVTILSLAQNIEYDIPTTLNVESLFSGRATKVDRFWQIKKNIRVLETW 79
Cdd:cd03801 1 KILLLSPELppPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRARRLLRELRPLLRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 80 FEqklrqlgsIDIVLSNLDRSNNLLAQSKIKNTHFVVHNSVNAELARQKKLGPLSYLYLKKSKQNL-NGKSLICVSKGVE 158
Cdd:cd03801 81 RK--------FDVVHAHGLLAALLAALLALLLGAPLVVTLHGAEPGRLLLLLAAERRLLARAEALLrRADAVIAVSEALR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 159 EEIQQGSLITPSAITTIYNPFNFKTINDKANEVNTNIPDSPYLIHVGRLAKQKRHDILFSAFAKLDKKY---KLVLL-CN 234
Cdd:cd03801 153 DELRALGGIPPEKIVVIPNGVDLERFSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRRGpdvRLVIVgGD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 235 KKEKALKLAKEYGIENQLIVPGFVQNP--YNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPhGPSEILTGELS 312
Cdd:cd03801 233 GPLRAELEELELGLGDRVRFLGFVPDEelPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVG-GLPEVVEDGEG 311
|
330 340
....*....|....*....|..
gi 1222442790 313 KYLVPIGQGELLALAVKQVLAD 334
Cdd:cd03801 312 GLVVPPDDVEALADALLRLLAD 333
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
3-336 |
1.58e-28 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 113.60 E-value: 1.58e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 3 IVIVIDSLVGGGAEKVMLTLAQEMVLKDHNVTILSLAQNIEYDIPTTLNVESLFSGRATKvdRFWQIKKNIRVLETWfeq 82
Cdd:cd03819 1 ILMLTPALEIGGAETYILDLARALAERGHRVLVVTAGGPLLPRLRQIGIGLPGLKVPLLR--ALLGNVRLARLIRRE--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 83 klrqlgSIDIVLSNLDRSNnLLAQ--SKIKNTHFV--VHNSVNAElarqkKLGPLSYLYLKKskqnlNGKSLICVSKGVE 158
Cdd:cd03819 76 ------RIDLIHAHSRAPA-WLGWlaSRLTGVPLVttVHGSYLAT-----YHPKDFALAVRA-----RGDRVIAVSELVR 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 159 EEIQQGSLITPSAITTIYNPFN---FKTINDKANEVNTNIPDSPYLI-HVGRLAKQKRHDILFSAFAKLDKKYKLVLLC- 233
Cdd:cd03819 139 DHLIEALGVDPERIRVIPNGVDtdrFPPEAEAEERAQLGLPEGKPVVgYVGRLSPEKGWLLLVDAAAELKDEPDFRLLVa 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 234 ---NKKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTEcPHGPSEILTGE 310
Cdd:cd03819 219 gdgPERDEIRRLVERLGLRDRVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATD-VGGAREIVVHG 297
|
330 340
....*....|....*....|....*.
gi 1222442790 311 LSKYLVPIGQGELLALAVKQVLADNP 336
Cdd:cd03819 298 RTGLLVPPGDAEALADAIRAAKLLPE 323
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
2-334 |
2.00e-26 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 108.17 E-value: 2.00e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 2 NIVIVIDSLVGGGAEKVMLTLAQEMVLKDHNVTILSL------AQNIE-YDIPT-TLNVESLFSGRATKVDRFWQIKKNI 73
Cdd:cd03807 1 KVAHVITGLNVGGAETMLLRLLEHMDKSRFEHVVISLtgdgvlGEELLaAGVPVvCLGLSSGKDPGVLLRLAKLIRKRNP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 74 RVLETWFEQKLrQLGSIdivlsnldrSNNLLAQSKIKNThfvVHNSVnaELARQKKLGPLSYLYLKKSkqnlnGKSLICV 153
Cdd:cd03807 81 DVVHTWMYHAD-LIGGL---------AAKLAGGVKVIWS---VRSSN--IPQRLTRLVRKLCLLLSKF-----SPATVAN 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 154 SKGVEEEIQQGSlITPSAITTIYN---PFNFKTINDKANEVNTNIP---DSPYLIHVGRLAKQKRHDILFSAFAKLDKK- 226
Cdd:cd03807 141 SSAVAEFHQEQG-YAKNKIVVIYNgidLFKLSPDDASRARARRRLGlaeDRRVIGIVGRLHPVKDHSDLLRAAALLVETh 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 227 --YKLVLLCN--KKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPhG 302
Cdd:cd03807 220 pdLRLLLVGRgpERPNLERLLLELGLEDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVG-G 298
|
330 340 350
....*....|....*....|....*....|..
gi 1222442790 303 PSEILtGELSKYLVPIGQGELLALAVKQVLAD 334
Cdd:cd03807 299 AAELV-DDGTGFLVPAGDPQALADAIRALLED 329
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
199-334 |
8.85e-23 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 92.57 E-value: 8.85e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 199 PYLIHVGRLAK-QKRHDILFSAFAKLDKK---YKLVLLCNKKEKALKLAKEyGIENQLIVPGFVQNPYNWIKQAKALLLS 274
Cdd:pfam13692 2 PVILFVGRLHPnVKGVDYLLEAVPLLRKRdndVRLVIVGDGPEEELEELAA-GLEDRVIFTGFVEDLAELLAAADVFVLP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 275 SDFEGFGNVLVEALAVGTPAVSTECPhGPSEILTGElSKYLVPIGQGELLALAVKQVLAD 334
Cdd:pfam13692 81 SLYEGFGLKLLEAMAAGLPVVATDVG-GIPELVDGE-NGLLVPPGDPEALAEAILRLLED 138
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
197-336 |
5.00e-22 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 91.18 E-value: 5.00e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 197 DSPYLIHVGRLAKQKRHDILFSAFAKLDKKYKLVLLC-----NKKEKALKLAKEYGIENQLIVPGFVQNPYNW--IKQAK 269
Cdd:pfam00534 1 KKKIILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLViagdgEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPelLKIAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222442790 270 ALLLSSDFEGFGNVLVEALAVGTPAVSTECPhGPSEILTGELSKYLVPIGQGELLALAVKQVLADNP 336
Cdd:pfam00534 81 VFVLPSRYEGFGIVLLEAMACGLPVIASDVG-GPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEE 146
|
|
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
145-357 |
8.36e-21 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 92.27 E-value: 8.36e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 145 LNGKSLICVSKGVEEEIQQGSLITPSAITTIYN------PFNFKTINdkanevntNIPDSPYLIHVGRLAKQKRHDILFS 218
Cdd:cd03808 138 LFTDKVIFVNEDDRDLAIKKGIIKKKKTVLIPGsgvdldRFQYSPES--------LPSEKVVFLFVARLLKDKGIDELIE 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 219 AFAKLDKKY---KLVLL--CNKKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTP 293
Cdd:cd03808 210 AAKILKKKGpnvRFLLVgdGELENPSEILIEKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRP 289
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1222442790 294 AVSTECPhGPSEILTGELSKYLVPIGQGELLALAVKQvLADNPNVT----NAA---ILEKVCADRVTEQYL 357
Cdd:cd03808 290 VITTDVP-GCRELVIDGVNGFLVPPGDVEALADAIEK-LIEDPELRkemgEAArkrVEEKFDEEKVVNKLL 358
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
150-336 |
5.26e-20 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 90.13 E-value: 5.26e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 150 LICVSKGVEEEIQqGSLITPSAITTIYNPFNFKT--INDKANEVNtniPDSPYLIHVGRLAKQKRHDILFSAFAKLDKKY 227
Cdd:cd03798 154 VIAVSKALAEELV-ALGVPRDRVDVIPNGVDPARfqPEDRGLGLP---LDAFVILFVGRLIPRKGIDLLLEAFARLAKAR 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 228 KLV--LLCN---KKEKALKLAKEYGIENQLIVPGFVqnPYN----WIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTE 298
Cdd:cd03798 230 PDVvlLIVGdgpLREALRALAEDLGLGDRVTFTGRL--PHEqvpaYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATD 307
|
170 180 190
....*....|....*....|....*....|....*...
gi 1222442790 299 CpHGPSEILTGELSKYLVPIGQGELLALAVKQVLADNP 336
Cdd:cd03798 308 V-GGIPEVVGDPETGLLVPPGDADALAAALRRALAEPY 344
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
3-295 |
1.67e-18 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 85.49 E-value: 1.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 3 IVIVIDSLVG--GGAEKVMLTLAQEMV-LKDHNVTILSLAQNIEYDIPTTLNVEslfsgratKVDRFWQIKKNIRVLETW 79
Cdd:cd03809 2 ILIDGRSLAQrlTGIGRYTRELLKALAkNDPDESVLAVPPLPGELLRLLREYPE--------LSLGVIKIKLWRELALLR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 80 FEQKLRQ-LGSIDIVLSNldrSNNLLAQSKIKNTHFVVHNSvnAELARQKKLGPLSYLYLKKS-KQNL-NGKSLICVSKG 156
Cdd:cd03809 74 WLQILLPkKDKPDLLHSP---HNTAPLLLKGCPQVVTIHDL--IPLRYPEFFPKRFRLYYRLLlPISLrRADAIITVSEA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 157 VEEEIQQGSLITPSAITTIYNPFN--FKTINDKANEVNTNIPDSPYLIHVGRLAKQKRHDILFSAFAKLDKK---YKLVL 231
Cdd:cd03809 149 TRDDIIKFYGVPPEKIVVIPLGVDpsFFPPESAAVLIAKYLLPEPYFLYVGTLEPRKNHERLLKAFALLKKQggdLKLVI 228
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1222442790 232 LC---NKKEKALKLAKEYGIENQLIVPGFVQNP--YNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAV 295
Cdd:cd03809 229 VGgkgWEDEELLDLVKKLGLGGRVRFLGYVSDEdlPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVI 297
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
2-338 |
3.50e-16 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 78.64 E-value: 3.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 2 NIVIVIDSLVGGGAEKVMLTLAQEMVLKDHNVTILSLAQNIEY------DIPTTLNVESLFSGRATKVdrfWQIKKNIRV 75
Cdd:cd04951 1 KILYVITGLGLGGAEKQTVLLADQMFIRGHDVNIVYLTGEVEVkplnnnIIIYNLGMDKNPRSLLKAL---LKLKKIISA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 76 LetwfeqklrqlgSIDIVLSNLdrsnnllaqskiknthfvVHNSVNAELARQkkLGPLSYLYLKKSKQNLNGK-SLIC-- 152
Cdd:cd04951 78 F------------KPDVVHSHM------------------FHANIFARFLRM--LYPIPLLICTAHNKNEGGRiRMFIyr 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 153 -----------VSKGVEEEIQQGSLITPSAITTIYNPFN---FKTINDKANEVNT--NIPDSPYLI-HVGRLAKQKRHDI 215
Cdd:cd04951 126 ltdflcdittnVSREALDEFIAKKAFSKNKSVPVYNGIDlnkFKKDINVRLKIRNklNLKNDEFVIlNVGRLTEAKDYPN 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 216 LFSAFAKLDK---KYKLVLLCN--KKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAV 290
Cdd:cd04951 206 LLLAISELILsknDFKLLIAGDgpLRNELERLICNLNLVDRVILLGQISNISEYYNAADLFVLSSEWEGFGLVVAEAMAC 285
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1222442790 291 GTPAVSTECpHGPSEILtgELSKYLVPIGQGELLALAVKQVLADNPNV 338
Cdd:cd04951 286 ERPVVATDA-GGVAEVV--GDHNYVVPVSDPQLLAEKIKEIFDMSDEE 330
|
|
| PRK09922 |
PRK09922 |
lipopolysaccharide 1,6-galactosyltransferase; |
153-313 |
9.46e-15 |
|
lipopolysaccharide 1,6-galactosyltransferase;
Pssm-ID: 182148 [Multi-domain] Cd Length: 359 Bit Score: 74.36 E-value: 9.46e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 153 VSKGVEEEIQqGSLITPSAITTIYNPFnfktindkanEVNTNIPDSP------YLIHVGRLA--KQKRHDILFSAFAKLD 224
Cdd:PRK09922 140 ISSGIKEQMM-ARGISAQRISVIYNPV----------EIKTIIIPPPerdkpaVFLYVGRLKfeGQKNVKELFDGLSQTT 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 225 KKYKLVLLCN--KKEKALKLAKEYGIENQLIVPGFVQNPYNW----IKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTE 298
Cdd:PRK09922 209 GEWQLHIIGDgsDFEKCKAYSRELGIEQRIIWHGWQSQPWEVvqqkIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSD 288
|
170
....*....|....*....
gi 1222442790 299 CPHGPSEI----LTGELSK 313
Cdd:PRK09922 289 CMSGPRDIikpgLNGELYT 307
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
202-310 |
2.86e-14 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 71.67 E-value: 2.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 202 IHVGRLAKQKRHDILFSAFAKLDKKY---KLVLLC---NKKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQ--AKALLL 273
Cdd:cd01635 114 VSVGRLVPEKGIDLLLEALALLKARLpdlVLVLVGgggEREEEEALAAALGLLERVVIIGGLVDDEVLELLLaaADVFVL 193
|
90 100 110
....*....|....*....|....*....|....*..
gi 1222442790 274 SSDFEGFGNVLVEALAVGTPAVSTECPHGPSEILTGE 310
Cdd:cd01635 194 PSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDGE 230
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
264-359 |
1.92e-13 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 66.17 E-value: 1.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 264 WIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPhGPSEILTGELSKYLVPIGQGELLALAVKQVLADNPNVTN--A 341
Cdd:COG0438 17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVG-GLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRlgE 95
|
90 100
....*....|....*....|..
gi 1222442790 342 AILEKVCA----DRVTEQYLAL 359
Cdd:COG0438 96 AARERAEErfswEAIAERLLAL 117
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
171-335 |
2.90e-13 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 69.64 E-value: 2.90e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 171 AITTIYNPFNFKTINDKANEVNTnipdspyLIHVGRLAKQKRHDILFSAFAKLDKKYKLVLL-----CNKKEKALKLAKE 245
Cdd:cd04949 140 TIPVGYVDQLDTAESNHERKSNK-------IITISRLAPEKQLDHLIEAVAKAVKKVPEITLdiygyGEEREKLKKLIEE 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 246 YGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPHGPSEILTGELSKYLVPIGQGELLA 325
Cdd:cd04949 213 LHLEDNVFLKGYHSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKYGPSELIEDGENGYLIEKNNIDALA 292
|
170
....*....|
gi 1222442790 326 LAVKQVLADN 335
Cdd:cd04949 293 DKIIELLNDP 302
|
|
| GT4_CapH-like |
cd03812 |
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ... |
3-314 |
1.36e-12 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).
Pssm-ID: 340840 [Multi-domain] Cd Length: 357 Bit Score: 68.08 E-value: 1.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 3 IVIVIDSLVGGGAEKVMLTLAQEMVLKDHNVTILSLAqniEYDIPTTLNVESL----FSGRATKVDrfwqIKKNIRVLet 78
Cdd:cd03812 2 ILHIVGGMNVGGIETFLMNLYRKLDKSKIEFDFLATS---DDKGEYDEELEELggkiFYIPPKKKN----IIKYFIKL-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 79 wfeQKLRQLGSIDIVLSNLDRSNN--LLAQSKIKNTHFVVHnSVNAELARQKKLgpLSYLYLKKSKQNLNGKSLICVSKG 156
Cdd:cd03812 73 ---LKLIKKEKYDIVHVHGSSSNGiiLLLAAKAGVPVRIAH-SHNTKDSSIKLR--KIRKNVLKKLIERLSTKYLACSED 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 157 VEEEIQqgSLITPSAITTIYNPFNFKTI--NDKANEVNT--NIPDSPYLI-HVGRLAKQKRHDILFSAFAKLDKK---YK 228
Cdd:cd03812 147 AGEWLF--GEVENGKFKVIPNGIDIEKYkfNKEKRRKRRklLILEDKLVLgHVGRFNEQKNHSFLIDIFEELKKKnpnVK 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 229 LVLLCN--KKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPhGPSEI 306
Cdd:cd03812 225 LVLVGEgeLKEKIKEKVKELGLEDKVIFLGFRNDVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCLLSDTI-TKECD 303
|
....*...
gi 1222442790 307 LTGELSKY 314
Cdd:cd03812 304 ITNNVEFL 311
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
151-295 |
1.79e-12 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 67.69 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 151 ICVSKGVEEEIQQGSLITPsaITTIYNPFNF----KTINDKANEVNTNIPDSPYLIHVGRLAKQKRHDILFSAFAKLDKK 226
Cdd:cd03817 152 IAPSEKIKDTLREYGVKGP--IEVIPNGIDLdkfeKPLNTEERRKLGLPPDEPILLYVGRLAKEKNIDFLLRAFAELKKE 229
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222442790 227 YKLVLLC----NKKEKALKLAKEYGIENQLIVPGFVqnPYNWI----KQAKALLLSSDFEGFGNVLVEALAVGTPAV 295
Cdd:cd03817 230 PNIKLVIvgdgPEREELKELARELGLADKVIFTGFV--PREELpeyyKAADLFVFASTTETQGLVYLEAMAAGLPVV 304
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
3-306 |
5.79e-12 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 66.24 E-value: 5.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 3 IVIVIDSLVGGGAeKVMLTLAQEMVLKDHNVTILSLAQNIEydipttlNVESLFSGRATKVDRFWQIKKNIRV------- 75
Cdd:cd03821 5 VTPSISPKAGGPV-KVVLRLAAALAALGHEVTIVSTGDGYE-------SLVVEENGRYIPPQDGFASIPLLRQgagrtdf 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 76 ---LETWFEQKLRQLgsiDIVLSNLDRSNNLLAQSKI-KNTH--FVV--HNSV---NAELARQKKLgPLSYLYLKkskQN 144
Cdd:cd03821 77 spgLPNWLRRNLREY---DVVHIHGVWTYTSLAACKLaRRRGipYVVspHGMLdpwALQQKHWKKR-IALHLIER---RN 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 145 LNGKSLICV-SKGVEEEIQQGSLITPSAIttIYNPFN---FKTINDKANEVNTnIPDSPYLIHVGRLAKQKRHDILFSAF 220
Cdd:cd03821 150 LNNAALVHFtSEQEADELRRFGLEPPIAV--IPNGVDipeFDPGLRDRRKHNG-LEDRRIILFLGRIHPKKGLDLLIRAA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 221 AKLDKK---YKLVLL---CNKKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALL--LSSDFEGFGNVLVEALAVGT 292
Cdd:cd03821 227 RKLAEQgrdWHLVIAgpdDGAYPAFLQLQSSLGLGDRVTFTGPLYGEAKWALYASADLfvLPSYSENFGNVVAEALACGL 306
|
330
....*....|....
gi 1222442790 293 PAVSTECPHGPSEI 306
Cdd:cd03821 307 PVVITDKCGLSELV 320
|
|
| GT4-like |
cd05844 |
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ... |
196-334 |
7.32e-09 |
|
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340860 [Multi-domain] Cd Length: 365 Bit Score: 56.69 E-value: 7.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 196 PDSPYLIHVGRLAKQKRHDILFSAFAKLDKKY---KLVLLCNKKEKALKLAKEYGIENqLIVPGFVQNP--YNWIKQAKA 270
Cdd:cd05844 187 ERAPTILFVGRLVEKKGCDVLIEAFRRLAARHptaRLVIAGDGPLRPALQALAAALGR-VRFLGALPHAevQDWMRRAEI 265
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1222442790 271 LLLSS------DFEGFGNVLVEALAVGTPAVSTEcpHG--PSEILTGElSKYLVPIGQGELLALAVKQVLAD 334
Cdd:cd05844 266 FCLPSvtaasgDSEGLGIVLLEAAACGVPVVSSR--HGgiPEAILDGE-TGFLVPEGDVDALADALQALLAD 334
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
153-359 |
1.70e-08 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 55.44 E-value: 1.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 153 VSKGVEEEIQqgSLITPSA-ITTIYNPFN---FKTINDKANEVNTNI-PDSPYLIHVGRLAKQKRHDILFSAFAKLDKKY 227
Cdd:cd04962 148 VSSSLRQETY--ELFDVDKdIEVIHNFIDedvFKRKPAGALKRRLLApPDEKVVIHVSNFRPVKRIDDVVRVFARVRRKI 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 228 --KLVLLCN--KKEKALKLAKEYGIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPHGP 303
Cdd:cd04962 226 paKLLLVGDgpERVPAEELARELGVEDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIP 305
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1222442790 304 SEILTGElSKYLVPIGQGELLALAVKQVLADNP--NVTNAAILEKV----CADRVTEQYLAL 359
Cdd:cd04962 306 EVVKHGE-TGFLSDVGDVDAMAKSALSILEDDElyNRMGRAARKRAaerfDPERIVPQYEAY 366
|
|
| Glyco_transf_4 |
pfam13439 |
Glycosyltransferase Family 4; |
13-180 |
2.39e-08 |
|
Glycosyltransferase Family 4;
Pssm-ID: 463877 [Multi-domain] Cd Length: 169 Bit Score: 52.92 E-value: 2.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 13 GGAEKVMLTLAQEMVLKDHNVTILSLAQNIEYDipttlnvESLFSGRATKVDRFWQIKKNIRVLETWFE--QKLRQLGsI 90
Cdd:pfam13439 1 GGVERYVLELARALARRGHEVTVVTPGGPGPLA-------EEVVRVVRVPRVPLPLPPRLLRSLAFLRRlrRLLRRER-P 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 91 DIVLSNLDRSNNLLAQSKIKNTH----FVVHNSVNAELARQKKLGPLSYLYLKKSKQNLNG-KSLICVSKGVEEEIQQGS 165
Cdd:pfam13439 73 DVVHAHSPFPLGLAALAARLRLGiplvVTYHGLFPDYKRLGARLSPLRRLLRRLERRLLRRaDRVIAVSEAVADELRRLY 152
|
170
....*....|....*
gi 1222442790 166 LITPSAITTIYNPFN 180
Cdd:pfam13439 153 GVPPEKIRVIPNGVD 167
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
196-334 |
6.23e-08 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 53.84 E-value: 6.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 196 PDSPYLIHVGRLAKQKRHDILFSAFAKLD--KKYKLVLLCNkkekalklakeyGIEN--------QLIVPGFVQNP---- 261
Cdd:cd03814 196 PGRPLLLYVGRLAPEKNLEALLDADLPLAasPPVRLVVVGD------------GPARaeleargpDVIFTGFLTGEelar 263
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1222442790 262 -YnwiKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPhGPSEILTGELSKYLVPIGQGELLALAVKQVLAD 334
Cdd:cd03814 264 aY---ASADVFVFPSRTETFGLVVLEAMASGLPVVAADAG-GPRDIVRPGGTGALVEPGDAAAFAAALRALLED 333
|
|
| GT4_AviGT4-like |
cd03802 |
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ... |
12-359 |
6.55e-08 |
|
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.
Pssm-ID: 340832 [Multi-domain] Cd Length: 333 Bit Score: 53.45 E-value: 6.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 12 GGGAEKVMLTLAQEMVLKDHNVTILSlaqniEYDIPTTLNVESLfSGRATKVDRFWQIKKNIRVLEtwFEQKLRQLGSID 91
Cdd:cd03802 17 YGGTELVVSALTEGLVRRGHEVTLFA-----PGDSHTSAPLVAV-IPRALRLDPIPQESKLAELLE--ALEVQLRASDFD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 92 IVLSNLDRSNNLLAQSKIKNTHFVVHNSvnaelarqkKLGPLSYLYLKKSKQNLngkslICVSKGveeeiQQGSLITPSA 171
Cdd:cd03802 89 VIHNHSYDWLPPFAPLIGTPFVTTLHGP---------SIPPSLAIYAAEPPVNY-----VSISDA-----QRAATPPIDY 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 172 ITTIYNPFnfktinDKANeVNTNIPDSPYLIHVGRLAKQKR-HD-ILFSAFAKLdkkyKLVLLcnkkEKALKLAKEYGIE 249
Cdd:cd03802 150 LTVVHNGL------DPAD-YRFQPDPEDYLAFLGRIAPEKGlEDaIRVARRAGL----PLKIA----GKVRDEDYFYYLQ 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 250 NQLIVP-----GFV----QNPYnwIKQAKALLLSSDF-EGFGNVLVEALAVGTPAVSTECpHGPSEILTGELSKYLVPiG 319
Cdd:cd03802 215 EPLPGPriefiGEVghdeKQEL--LGGARALLFPINWdEPFGLVMIEAMACGTPVIAYRR-GGLPEVIQHGETGFLVD-S 290
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1222442790 320 QGELLAlAVKQVLADNPNVTNAAILEKVCADRVTEQYLAL 359
Cdd:cd03802 291 VEEMAE-AIANIDRIDRAACRRYAEDRFSAARMADRYEAL 329
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
196-358 |
8.41e-08 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 53.40 E-value: 8.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 196 PDSPYLIHVGRLAKQKRHDILFSAFAKLDKKYKLVLLC-----------NKKEKALKLAKEYGIENQLIVPGFV---QNP 261
Cdd:cd03800 218 PDKPVVLALGRLDPRKGIDTLVRAFAQLPELRELANLVlvggpsddplsMDREELAELAEELGLIDRVRFPGRVsrdDLP 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 262 yNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTeCPHGPSEILTGELSKYLVPIGQGELLALAVKQVLADnPNVTNA 341
Cdd:cd03800 298 -ELYRAADVFVVPSLYEPFGLTAIEAMACGTPVVAT-AVGGLQDIVRDGRTGLLVDPHDPEALAAALRRLLDD-PALWQR 374
|
170 180
....*....|....*....|....
gi 1222442790 342 ---AILEKVCA----DRVTEQYLA 358
Cdd:cd03800 375 lsrAGLERARAhytwESVADQLLT 398
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
134-334 |
1.06e-07 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 53.10 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 134 SYLYLKK--SKQNLNGK---------SLICVSKGVEEEIQQGSLITPSAITTIYNPFN---FKTINDKANEVNTNIPDSP 199
Cdd:cd03825 114 SYPPAKKdlSRQLFRRKrealakkrlTIVAPSRWLADMVRRSPLLKGLPVVVIPNGIDteiFAPVDKAKARKRLGIPQDK 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 200 YLIHVGRLA---KQKRHDILFSAFAKLDKKYKLVLLCnkkekalklakeYGIENQLIVP-GFVQNPYNWIK--------- 266
Cdd:cd03825 194 KVILFGAESvtkPRKGFDELIEALKLLATKDDLLLVV------------FGKNDPQIVIlPFDIISLGYIDddeqlvdiy 261
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1222442790 267 -QAKALLLSSDFEGFGNVLVEALAVGTPAVSTECPhGPSEILTGELSKYLVPIGQGELLALAVKQVLAD 334
Cdd:cd03825 262 sAADLFVHPSLADNLPNTLLEAMACGTPVVAFDTG-GSPEIVQHGVTGYLVPPGDVQALAEAIEWLLAN 329
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
4-359 |
5.77e-05 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 44.63 E-value: 5.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 4 VIVIDSLV----GGGAEKVMLTLAQEMVLKDHNVTILSlAQNIEYDIPTTLNvESLFSGRATKVDRFWQIKKNIR----- 74
Cdd:cd03823 2 ILLVNSLYppqrVGGAEISVHDLAEALVAEGHEVAVLT-AGVGPPGQATVAR-SVVRYRRAPDETLPLALKRRGYelfet 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 75 ---VLETWFEQKLRQLgSIDIVLSN--LDRSNNLL---AQSKIKnthfVVHNSVNAEL--ARQKKLGPlsylylkkskqn 144
Cdd:cd03823 80 ynpGLRRLLARLLEDF-RPDVVHTHnlSGLGASLLdaaRDLGIP----VVHTLHDYWLlcPRQFLFKK------------ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 145 lNGKSLICVSKgVEEEIQQGSLITPSAITTIYNPFNFktinDKANEVNTNIPDSPY-LIHVGRLAKQKRHDILFSAFAKL 223
Cdd:cd03823 143 -GGDAVLAPSR-FTANLHEANGLFSARISVIPNAVEP----DLAPPPRRRPGTERLrFGYIGRLTEEKGIDLLVEAFKRL 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 224 D-KKYKLVLLCNKKEKALKLakeYGIENQLIVPGFVQNpynwiKQAKALLLSSDF--------EGFGNVLVEALAVGTPA 294
Cdd:cd03823 217 PrEDIELVIAGHGPLSDERQ---IEGGRRIAFLGRVPT-----DDIKDFYEKIDVlvvpsiwpEPFGLVVREAIAAGLPV 288
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1222442790 295 VSTEcPHGPSEILTGELSKYLVPIGQGELLALAVKQVLADnPNVTN---AAILEKVCADRVTEQYLAL 359
Cdd:cd03823 289 IASD-LGGIAELIQPGVNGLLFAPGDAEDLAAAMRRLLTD-PALLErlrAGAEPPRSTESQAEEYLKL 354
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
247-334 |
8.43e-05 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 44.25 E-value: 8.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 247 GIENQLIVPGFvQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTE---CPhgpsEILTGELSKY-----LVPI 318
Cdd:cd03813 351 GLENKVKFLGF-QNIKEYYPKLGLLVLTSISEGQPLVILEAMASGVPVVATDvgsCR----ELIYGADDALgqaglVVPP 425
|
90
....*....|....*.
gi 1222442790 319 GQGELLALAVKQVLAD 334
Cdd:cd03813 426 ADPEALAEALIKLLRD 441
|
|
| GT4_WfcD-like |
cd03795 |
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ... |
13-334 |
1.12e-04 |
|
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340826 [Multi-domain] Cd Length: 355 Bit Score: 43.80 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 13 GGAEKVMLTLAQEMVLKDHNVTILSLAQNIEYDIPTTLNVESLFSGRATKVDR---FWQIKKNIRVLETWFeqklrqlgs 89
Cdd:cd03795 14 GGIEQVIYDLAEGLKKKGIEVDVLCFSKEKETPEKEENGIRIHRVKSFLNVAStpfSPSYIKRFKKLAKEY--------- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 90 iDIV-------LSNLdrsnnLLAQSKIKNThFVVHnsVNAELARQKKL----GPLSYLYLKKSKQNLNGKSLICVSKGVE 158
Cdd:cd03795 85 -DIIhyhfpnpLADL-----LLFFSGAKKP-VVVH--WHSDIVKQKKLlklyKPLMTRFLRRADRIIATSPNYVETSPTL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 159 EEIQQGSLITPSAIttiyNPfNFKTINDKANE-VNTNIPDSPYLIHVGRLAKQKRHDILFSAFAKLDkkYKLVLL--CNK 235
Cdd:cd03795 156 REFKNKVRVIPLGI----DK-NVYNIPRVDFEnIKREKKGKKIFLFIGRLVYYKGLDYLIEAAQYLN--YPIVIGgeGPL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 236 KEKALKLAKEYGIENQLIVpGFV--QNPYNWIKQAKALLLSSDF--EGFGNVLVEALAVGTPAVSTECPHGPSEILTGEL 311
Cdd:cd03795 229 KPDLEAQIELNLLDNVKFL-GRVddEEKVIYLHLCDVFVFPSVLrsEAFGIVLLEAMMCGKPVISTNIGTGVPYVNNNGE 307
|
330 340
....*....|....*....|...
gi 1222442790 312 SKYLVPIGQGELLALAVKQVLAD 334
Cdd:cd03795 308 TGLVVPPKDPDALAEAIDKLLSD 330
|
|
| PRK15179 |
PRK15179 |
Vi polysaccharide biosynthesis protein TviE; Provisional |
247-334 |
3.13e-04 |
|
Vi polysaccharide biosynthesis protein TviE; Provisional
Pssm-ID: 185101 [Multi-domain] Cd Length: 694 Bit Score: 42.71 E-value: 3.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 247 GIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTECpHGPSEILTGELSKYLVPIGQ------ 320
Cdd:PRK15179 571 GMGERILFTGLSRRVGYWLTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLA-GGAGEAVQEGVTGLTLPADTvtapdv 649
|
90
....*....|....
gi 1222442790 321 GELLALAVKQVLAD 334
Cdd:PRK15179 650 AEALARIHDMCAAD 663
|
|
| GT4_AmsK-like |
cd03799 |
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ... |
166-325 |
5.16e-04 |
|
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.
Pssm-ID: 340829 [Multi-domain] Cd Length: 350 Bit Score: 41.67 E-value: 5.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 166 LITPSAITTiyNPFNFKTINDKANEvntnipdSPYLIHVGRLAKQKRHDILFSAFAKLDKK-----YKLVLLCNKKEKAL 240
Cdd:cd03799 151 IVHRSGIDC--NKFRFKPRYLPLDG-------KIRILTVGRLTEKKGLEYAIEAVAKLAQKypnieYQIIGDGDLKEQLQ 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222442790 241 KLAKEYGIENQLIVPGFVQNP--YNWIKQAKALLLSS------DFEGFGNVLVEALAVGTPAVSTEcpH-GPSEILTGEL 311
Cdd:cd03799 222 QLIQELNIGDCVKLLGWKPQEeiIEILDEADIFIAPSvtaadgDQDGPPNTLKEAMAMGLPVISTE--HgGIPELVEDGV 299
|
170
....*....|....
gi 1222442790 312 SKYLVPIGQGELLA 325
Cdd:cd03799 300 SGFLVPERDAEAIA 313
|
|
| PRK15490 |
PRK15490 |
Vi polysaccharide biosynthesis glycosyltransferase TviE; |
247-304 |
2.05e-03 |
|
Vi polysaccharide biosynthesis glycosyltransferase TviE;
Pssm-ID: 185387 [Multi-domain] Cd Length: 578 Bit Score: 40.07 E-value: 2.05e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1222442790 247 GIENQLIVPGFVQNPYNWIKQAKALLLSSDFEGFGNVLVEALAVGTPAVSTecPHGPS 304
Cdd:PRK15490 452 GILERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVIST--PAGGS 507
|
|
| |
