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Conserved domains on  [gi|1215507673|gb|ASK90466|]
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transcriptional regulator [Xanthomonas citri pv. vignicola]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 10787697)

helix-turn-helix (HTH) transcriptional regulator containing a XRE (Xenobiotic Response Element) family HTH domain may act as a transcriptional regulator that controls the expression of genes involved in stress response

CATH:  1.10.10.10
Gene Ontology:  GO:0003677
PubMed:  10473770|2644244

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-64 2.21e-27

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


:

Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 93.37  E-value: 2.21e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1215507673  1 MNSRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHVFLYED 64
Cdd:COG1476    5 LGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
 
Name Accession Description Interval E-value
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-64 2.21e-27

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 93.37  E-value: 2.21e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1215507673  1 MNSRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHVFLYED 64
Cdd:COG1476    5 LGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
4-59 2.59e-18

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 70.24  E-value: 2.59e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1215507673   4 RVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHV 59
Cdd:smart00530  1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 3-57 2.68e-17

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 67.58  E-value: 2.68e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1215507673  3 SRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:cd00093    2 ERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLD 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 5-57 7.48e-16

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 64.10  E-value: 7.48e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 1215507673  5 VRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:pfam01381  1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLD 53
PRK04140 PRK04140
transcriptional regulator;
6-56 2.11e-09

transcriptional regulator;


Pssm-ID: 235224 [Multi-domain]  Cd Length: 317  Bit Score: 51.01  E-value: 2.11e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1215507673   6 RELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESI 56
Cdd:PRK04140  132 REAREELGLSLGELASELGVSRRTISKYENGGMNASIEVAIKLEEILDVPL 182
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 5-53 1.22e-07

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 43.42  E-value: 1.22e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 1215507673  5 VRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFG 53
Cdd:TIGR03070  7 VRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLDALG 55
 
Name Accession Description Interval E-value
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-64 2.21e-27

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 93.37  E-value: 2.21e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1215507673  1 MNSRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHVFLYED 64
Cdd:COG1476    5 LGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
4-59 2.59e-18

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 70.24  E-value: 2.59e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1215507673   4 RVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHV 59
Cdd:smart00530  1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 3-57 2.68e-17

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 67.58  E-value: 2.68e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1215507673  3 SRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:cd00093    2 ERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLD 56
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-64 7.09e-17

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 67.33  E-value: 7.09e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1215507673  1 MNSRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHVFLYED 64
Cdd:COG1396    8 LGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGAD 71
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 5-57 7.48e-16

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 64.10  E-value: 7.48e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 1215507673  5 VRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:pfam01381  1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLD 53
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 3-57 7.95e-16

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 64.19  E-value: 7.95e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1215507673  3 SRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:COG1813   15 ERIREAREARGLSQEELAEKLGVSESTIRRIERGEATPSLDTLRKLEKALGISLA 69
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 5-65 1.55e-14

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 61.57  E-value: 1.55e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1215507673  5 VRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHVFLYEDG 65
Cdd:COG3620   22 LRLMRKELGLSQLPVAELVGVSQSDILRIESGKRDPTVSTLEKIAEALGKELSAVLVVDDG 82
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 4-60 5.27e-14

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 59.61  E-value: 5.27e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1215507673  4 RVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHVF 60
Cdd:pfam12844  3 RLRKAREERGLTQEELAERLGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWLL 59
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 6-57 5.30e-12

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 54.82  E-value: 5.30e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1215507673  6 RELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:COG3093   15 EEFLEPLGLSQTELAKALGVSRQRISEILNGKRAITADTALRLARAFGTSAE 66
COG1395 COG1395
Predicted transcriptional regulator [Transcription];
6-56 2.39e-11

Predicted transcriptional regulator [Transcription];


Pssm-ID: 441005 [Multi-domain]  Cd Length: 313  Bit Score: 56.38  E-value: 2.39e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1215507673   6 RELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESI 56
Cdd:COG1395   133 RELREERGLSLGELASELGVSRRTISKYERGEMDASIEVALKLEEILGEPI 183
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 4-53 1.35e-09

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 48.29  E-value: 1.35e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 1215507673  4 RVRELREANGWSQGELGERLGVSRQTINALETGKYD-PSLPLAFRIARLFG 53
Cdd:pfam13560  5 RLRRLRERAGLSQEALARRLGVSRSTLSRLETGRRGrPSPAVVERLARALG 55
PRK04140 PRK04140
transcriptional regulator;
6-56 2.11e-09

transcriptional regulator;


Pssm-ID: 235224 [Multi-domain]  Cd Length: 317  Bit Score: 51.01  E-value: 2.11e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1215507673   6 RELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESI 56
Cdd:PRK04140  132 REAREELGLSLGELASELGVSRRTISKYENGGMNASIEVAIKLEEILDVPL 182
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
4-43 2.66e-08

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 44.92  E-value: 2.66e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 1215507673  4 RVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLP 43
Cdd:COG2944   10 EIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGA 49
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 5-53 1.22e-07

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 43.42  E-value: 1.22e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 1215507673  5 VRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFG 53
Cdd:TIGR03070  7 VRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLDALG 55
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 4-53 4.22e-07

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 42.10  E-value: 4.22e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1215507673  4 RVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAF------RIARLFG 53
Cdd:COG1426    9 LLRQAREAKGLSLEDVAERTKISVSYLEAIEEGDFDALPGPVYvrgflrSYARALG 64
PHA01976 PHA01976
helix-turn-helix protein
 4-57 3.82e-05

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 37.24  E-value: 3.82e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 1215507673  4 RVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:PHA01976   6 QLIKARNARAWSAPELSRRAGVRHSLIYDFEADKRLPNLKTLLRLADALGVTLD 59
mob_myst_A TIGR02612
mobile mystery protein A; Members of this protein family are found in mobization-related ...
 5-62 3.98e-05

mobile mystery protein A; Members of this protein family are found in mobization-related contexts more often than not, including within a CRISPR-associated gene region in Geobacter sulfurreducens PCA, and on plasmids in Agrobacterium tumefaciens and Coxiella burnetii, always together with mobile mystery protein B, a member of the Fic protein family (pfam02661). This protein is encoded by the upstream member of the gene pair and belongs to a family of helix-turn-helix DNA binding proteins (pfam01381). [Unknown function, General]


Pssm-ID: 274231  Cd Length: 150  Bit Score: 38.64  E-value: 3.98e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1215507673   5 VRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLafRIARLFGESIEHVFLY 62
Cdd:TIGR02612  30 VRAIRKALGMSGAQLAGRLGVTPQRVEALEKSELSGTVTL--KTLRAAAEALDCTFVY 85
antidote_HigA TIGR02607
addiction module antidote protein, HigA family; Members of this family form a distinct clade ...
 10-57 6.08e-05

addiction module antidote protein, HigA family; Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other]


Pssm-ID: 274228 [Multi-domain]  Cd Length: 78  Bit Score: 36.83  E-value: 6.08e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1215507673 10 EANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:TIGR02607 15 EPLGLSVRALAKALGVSRSTLSRIVNGRAAITADMALRLAKALGTSPE 62
HTH_25 pfam13413
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 6-43 1.46e-04

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433187 [Multi-domain]  Cd Length: 62  Bit Score: 35.55  E-value: 1.46e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 1215507673  6 RELREANGWSQGELGERLGVSRQTINALETGKYDpSLP 43
Cdd:pfam13413  3 RAAREARGLSLEDVAERTKIRPRYLEALEEDDFD-ALP 39
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 4-64 1.62e-04

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 35.21  E-value: 1.62e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1215507673  4 RVRELREANGWSQGELGERLGVSRQTINALETGKYD-PSLPLAFRIARLFGESIEHVFLYED 64
Cdd:pfam13443  1 KLRKLMADRGISKSDLARATGISRATLSRLRKGKPKrVSLDTLDKICDALGCQPGDLLEYVP 62
HTH_37 pfam13744
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain.
 3-52 5.94e-04

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain.


Pssm-ID: 433449 [Multi-domain]  Cd Length: 80  Bit Score: 34.51  E-value: 5.94e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 1215507673  3 SRVRELREANGWSQGELGERLGVSRQTINALETGKYDpslplAFRIARLF 52
Cdd:pfam13744 21 RAIARLIEGRGLSQQEAAALLGIAQPKVSALLKGKLS-----RFSLDKLL 65
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 5-49 5.94e-04

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 34.91  E-value: 5.94e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1215507673   5 VRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPL--AFRIA 49
Cdd:TIGR03830  70 IRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSKALdkLLRLL 116
PRK09726 PRK09726
type II toxin-antitoxin system antitoxin HipB;
8-48 7.05e-04

type II toxin-antitoxin system antitoxin HipB;


Pssm-ID: 182049  Cd Length: 88  Bit Score: 34.57  E-value: 7.05e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 1215507673  8 LREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRI 48
Cdd:PRK09726  20 VRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKI 60
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
1-60 8.34e-04

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 35.15  E-value: 8.34e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215507673   1 MNSRVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIEHVF 60
Cdd:PRK09943    8 PGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFF 67
COG5606 COG5606
Predicted DNA-binding protein, XRE-type HTH domain [General function prediction only];
3-52 1.26e-03

Predicted DNA-binding protein, XRE-type HTH domain [General function prediction only];


Pssm-ID: 444337  Cd Length: 105  Bit Score: 34.09  E-value: 1.26e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1215507673   3 SRVRELREANGWSQGELGERLGVSRQTINALETGKYDpslplAFRIARLF 52
Cdd:COG5606    35 AAIRKLIKERGLTQAEAAELLGITQPRVSDLLRGKIS-----KFSLDKLV 79
COG1356 COG1356
Transcriptional regulator [Transcription];
5-34 1.97e-03

Transcriptional regulator [Transcription];


Pssm-ID: 440967 [Multi-domain]  Cd Length: 139  Bit Score: 33.67  E-value: 1.97e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1215507673   5 VRELREAnGWSQGELGERLGVSRQTINALE 34
Cdd:COG1356    16 VLALRER-GLTQQEIADILGTSRANVSSIE 44
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 4-57 3.57e-03

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 33.39  E-value: 3.57e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1215507673   4 RVRELREANGWSQGELGERLGVSRQTINALETGKYDPSLPLAFRIARLFGESIE 57
Cdd:PRK08154   32 RVRTLRARRGMSRKVLAQASGVSERYLAQLESGQGNVSILLLRRVARALGCSLA 85
HTH_11 pfam08279
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
 5-30 3.71e-03

HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.


Pssm-ID: 429896 [Multi-domain]  Cd Length: 52  Bit Score: 31.63  E-value: 3.71e-03
                         10        20
                 ....*....|....*....|....*..
gi 1215507673  5 VRELREANG-WSQGELGERLGVSRQTI 30
Cdd:pfam08279  4 LQLLLEARGpISGQELAEKLGVSRRTI 30
HTH_Hin_like cd00569
Helix-turn-helix domain of Hin and related proteins; This domain model summarizes a family of ...
 4-30 9.26e-03

Helix-turn-helix domain of Hin and related proteins; This domain model summarizes a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed helical bundle. The principal DNA-protein interface is formed by the third helix, the recognition helix, inserting itself into the major groove of the DNA. A diverse array of HTH domains participate in a variety of functions that depend on their DNA-binding properties. HTH_Hin represents one of the simplest versions of the HTH domains; the characterization of homologous relationships between various sequence-diverse HTH domain families remains difficult. The Hin recombinase induces the site-specific inversion of a chromosomal DNA segment containing a promoter, which controls the alternate expression of two genes by reversibly switching orientation. The Hin recombinase consists of a single polypeptide chain containing a C-terminal DNA-binding domain (HTH_Hin) and a catalytic domain.


Pssm-ID: 259851 [Multi-domain]  Cd Length: 42  Bit Score: 30.37  E-value: 9.26e-03
                         10        20
                 ....*....|....*....|....*....
gi 1215507673  4 RVRELRE--ANGWSQGELGERLGVSRQTI 30
Cdd:cd00569   10 QIAEARRllAAGESVAEIARELGVSRSTL 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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