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Conserved domains on  [gi|1197509908|ref|YP_009363752|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Dicrostonyx torquatus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 4.72e-69

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 206.96  E-value: 4.72e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   1 MTELIYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  81 TWVSSWLVFGILVMSIFMEMGMLFVSHYYEGLDVVLEFNSMGGWAVYDGDGLGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|....
gi 1197509908 161 FMGVFIIIEITRGN 174
Cdd:MTH00109  162 FIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 4.72e-69

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 206.96  E-value: 4.72e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   1 MTELIYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  81 TWVSSWLVFGILVMSIFMEMGMLFVSHYYEGLDVVLEFNSMGGWAVYDGDGLGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|....
gi 1197509908 161 FMGVFIIIEITRGN 174
Cdd:MTH00109  162 FIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 1.67e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 45.19  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  17 LGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPETWVSSWLVFGILVMSI 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1197509908  97 FMEMGMLFvshyyegldvVLEFNSMGGWAVYDGDGLGLMGEGGagvAALYSCSAWLMVVSGWTLFMGVFIIIEI 170
Cdd:pfam00499  81 LLLALLLL----------VLLSASLTPAAAAAAPDVGNIEAIG---ELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 4.72e-69

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 206.96  E-value: 4.72e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   1 MTELIYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  81 TWVSSWLVFGILVMSIFMEMGMLFVSHYYEGLDVVLEFNSMGGWAVYDGDGLGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|....
gi 1197509908 161 FMGVFIIIEITRGN 174
Cdd:MTH00109  162 FIGVFVIIEITRGN 175
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 1.19e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 88.75  E-value: 1.19e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   1 MTELIYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  81 TWvSSWLVFGILVMSIFmemgMLFVSHYYEGLDVVLEFnsmggWAVYDGDGLGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00065   81 AW-GSWSVLVYVLFYLL----LLIVGYILFGCNFSLEF-----LFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                         170
                  ....*....|...
gi 1197509908 161 FMGVFIIIEITRG 173
Cdd:MTH00065  151 LLTLFVVLEVTRG 163
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.09e-21

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 86.35  E-value: 1.09e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   1 MTELIYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  81 TWvSSWLVFGILVMSIF--MEMGMLFVSHYYEGLDVVlefnsmggwaVYDGDGLGLMGEGGAGVAALYSCSAWLMVVSGW 158
Cdd:MTH00138   81 SW-GSWSVLGYVVGYLVgvVLAAGLFWGGWYEGSWVV----------VDELKEFSVLRGDVGGVALMYSSGGGMLVICAW 149

                         170
                  ....*....|....*
gi 1197509908 159 TLFMGVFIIIEITRG 173
Cdd:MTH00138  150 VLLLTLFVVLELTRG 164
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 9.35e-17

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 73.24  E-value: 9.35e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   1 MTELIYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  81 TWVSSWLVFGILVMSIFMEMGMLFVSHYYEGLDVvlefnsmgGWAVYDGDGLGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGV--------GVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGL 152

                         170
                  ....*....|...
gi 1197509908 161 FMGVFIIIEITRG 173
Cdd:MTH00115  153 LLTLFVVLELVRG 165
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 5-174 8.06e-10

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 54.53  E-value: 8.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   5 IYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPEtwVS 84
Cdd:MTH00045    3 FYLFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS--VS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  85 SWLVFGILVMSIfmemgmlfvshyyeGLDVVLEFNSMGGWAVYDGDGLGLMGEGGAGVaaLYSCSAWLMVVSGWTLFMGV 164
Cdd:MTH00045   81 NLGEVLVLSLLL--------------SLWVFISFDNFLELSNNNWSLVSLSDLVGSSE--LYNSGGLYLLLGGFILLVAL 144

                         170
                  ....*....|
gi 1197509908 165 FIIIEITRGN 174
Cdd:MTH00045  145 VVALVISFGH 154
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 2.38e-09

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 53.45  E-value: 2.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   1 MTELIYLSSLLVALGCLGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  81 TWVSswlvfgilvmsifmEMGMLFVSHYYEGLDVVLEFNSMGGWAVYDGDGLGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00214   81 SWGG--------------WSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVL 146

                         170
                  ....*....|...
gi 1197509908 161 FMGVFIIIEITRG 173
Cdd:MTH00214  147 FLVLFVVLELVRG 159
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 1.67e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 45.19  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908  17 LGTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYPETWVSSWLVFGILVMSI 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1197509908  97 FMEMGMLFvshyyegldvVLEFNSMGGWAVYDGDGLGLMGEGGagvAALYSCSAWLMVVSGWTLFMGVFIIIEI 170
Cdd:pfam00499  81 LLLALLLL----------VLLSASLTPAAAAAAPDVGNIEAIG---ELLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 4-116 6.66e-05

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 41.14  E-value: 6.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197509908   4 LIYLSSLLVALGCLgTSLKPSPIYGGLCLIISGCSGCLAVLGLGGSFLGLMVFLIYLGGMMVVFGYTTAMSAEEYpetWV 83
Cdd:MTH00212    3 LSLLLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH---LF 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1197509908  84 SSWLVFGILVMSIFMEMGMLFVSHYYEGLDVVL 116
Cdd:MTH00212   79 FKKYFKGFGMILISLNLYLLLMTLGSSNFSPML 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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