NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|119611609|gb|EAW91203|]
View 

translocated promoter region (to activated MET oncogene), isoform CRA_a [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 1115-1241 4.13e-27

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


:

Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 108.11  E-value: 4.13e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1115 LSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1194
Cdd:pfam07926    3 LSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQALREELNELKAEIAELKAEAES 82

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 119611609  1195 AESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1241
Cdd:pfam07926   83 AKAELEESEESWEEQKKELEKELSELEKRIEDLNEQNKLLHDQLESL 129
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 848-1694 4.08e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 4.08e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   848 KLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRL---SSQIEKLEHEIS 924
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   925 HLKKKLENEVEQRhtltRNLDVQLLDTKRQLD-TETNLHLNTKELlKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQP 1003
Cdd:TIGR02168  306 ILRERLANLERQL----EELEAQLEELESKLDeLAEELAELEEKL-EELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1004 SN--KEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLnkEKQVTEEVRKNIEVRLKESAEFQTQLEK 1081
Cdd:TIGR02168  381 LEtlRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQEELER 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1082 KLMEVEKEKQELqDDKRRAIESMEQQLSELKKTLSSVQNEVQEA--LQRASTALSNEQQARRDCQEQAKIAVEAQNKYER 1159
Cdd:TIGR02168  459 LEEALEELREEL-EEAEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1160 EL------MLHAADVEALQAAKEQVS---KMASVRQHLEETTQKAESQLleckaswEERERMLKDEVSKCVCRCEDLEKQ 1230
Cdd:TIGR02168  538 AIeaalggRLQAVVVENLNAAKKAIAflkQNELGRVTFLPLDSIKGTEI-------QGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1231 NRLLHDQIEKLSDKVVasVKEGVQGPLNVslseegksQEQILEILRFIRREKEIAETRFEVAqveslryrqrvellerel 1310
Cdd:TIGR02168  611 DPKLRKALSYLLGGVL--VVDDLDNALEL--------AKKLRPGYRIVTLDGDLVRPGGVIT------------------ 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1311 qelqdslnaeREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIlplqeanAELS 1390
Cdd:TIGR02168  663 ----------GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL-------EELS 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1391 EKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNN--- 1467
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrea 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1468 ----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKvmetsaqssgdHQE 1543
Cdd:TIGR02168  805 ldelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-----------LES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1544 QHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQD---LQDRTTQEEQLRQ 1619
Cdd:TIGR02168  874 ELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnLQERLSEEYSLTL 953

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1620 Q--------ITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvriTALKSQYEGRISRLERE 1691
Cdd:TIGR02168  954 EeaealenkIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDL----TEAKETLEEAIEEIDRE 1029


                   ...
gi 119611609  1692 LRE 1694
Cdd:TIGR02168 1030 ARE 1032
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-1141 6.78e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 6.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   302 ENKKEEVSRLEEqmnglktSNEHLQKhVEDLLTKLKEAK---EQQASMEEKFHnELNAHIK------LSNLYKSAADDSE 372
Cdd:TIGR02168  172 ERRKETERKLER-------TRENLDR-LEDILNELERQLkslERQAEKAERYK-ELKAELRelelalLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   373 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEqskdqmekEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 452
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVS--------ELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   453 MSPTAAAVAKIVKPGMKLTELynayvetqdQLLLEKLENKrinkyLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVK 532
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDEL---------AEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   533 LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhl 612
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE------------ 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   613 vsyrnIEELQQQNQRLLVALRELgetreREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSiVRQRDMYRIL 692
Cdd:TIGR02168  449 -----LEELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   693 LSQTTGVAIPLH--------------ASSLDDV---------SLASTPKRPSTSQTvsTPAPVPVIESTEAIEAKAALKQ 749
Cdd:TIGR02168  518 LSGILGVLSELIsvdegyeaaieaalGGRLQAVvvenlnaakKAIAFLKQNELGRV--TFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   750 LQEIFENYKKEKAE-NEKIQN------------EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQdnveGYRREITS 816
Cdd:TIGR02168  596 NIEGFLGVAKDLVKfDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITG----GSAKTNSS 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   817 LHERNQKLTATTQKQEQiintMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnlqt 896
Cdd:TIGR02168  672 ILERRREIEELEEKIEE----LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD------------- 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   897 iqgilersetetKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLhlntKELLKNAQKEI 976
Cdd:TIGR02168  735 ------------LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL----EAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   977 ATLKQHLS--NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-- 1052
Cdd:TIGR02168  799 KALREALDelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEal 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1053 -KEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQN-EVQEALQ 1127
Cdd:TIGR02168  879 lNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEA 958

                          890
                   ....*....|....
gi 119611609  1128 RASTALSNEQQARR 1141
Cdd:TIGR02168  959 LENKIEDDEEEARR 972
YhaN super family cl34808
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
105-447 5.24e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


The actual alignment was detected with superfamily member COG4717:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  105 LADQQSEIDGLKGRHEKF------KVESEQQYFEIEKRLSHSQERL---------VNETRECQSLRLELEKLNNQLKALT 169
Cdd:COG4717    73 LKELEEELKEAEEKEEEYaelqeeLEELEEELEELEAELEELREELeklekllqlLPLYQELEALEAELAELPERLEELE 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  170 EKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDL----IRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDEL 245
Cdd:COG4717   153 ERLEELRELEEELEELEAELAELQEELEELLEQLslatEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  246 QASDVSVKAKKRLEQEKELL--------HSQNTWLNTELKTKTDELLALG---------------REKGNEILELKCNLE 302
Cdd:COG4717   233 ENELEAAALEERLKEARLLLliaaallaLLGLGGSLLSLILTIAGVLFLVlgllallflllarekASLGKEAEELQALPA 312

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  303 NKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH--NELNAHIKLSNLYKSAADDSEAKSNELTR 380
Cdd:COG4717   313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAEAGVEDEEELRAALE 392

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609  381 AVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML-EKIGRLEKEL-ENANDLLSATKRKGAILSE 447
Cdd:COG4717   393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEELeEELEELEEELeELEEELEELREELAELEAE 461
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1724-1900 2.46e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 43.37  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1724 TTPASGERGIASTSDPPTAN-IKPTPVVSTPSKVTAAAMAGNKSTPRASIRPmvtpaTVTNPTTTPTATVMPTTQVESQE 1802
Cdd:pfam05109  535 TSPTLGKTSPTSAVTTPTPNaTSPTPAVTTPTPNATIPTLGKTSPTSAVTTP-----TPNATSPTVGETSPQANTTNHTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1803 AMQSEGPVEHVPVFGSTSG---------SVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHP-------QIEPAnq 1866
Cdd:pfam05109  610 GGTSSTPVVTSPPKNATSAvttgqhnitSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPtggenitQVTPA-- 687

                          170       180       190
                   ....*....|....*....|....*....|....
gi 119611609  1867 elSSNIVEVVQSSPVERPSTSTAVFGTVSATPSS 1900
Cdd:pfam05109  688 --STSTHHVSTSSPAPRPGTTSQASGPGNSSTST 719
 
Name Accession Description Interval E-value
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 1115-1241 4.13e-27

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 108.11  E-value: 4.13e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1115 LSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1194
Cdd:pfam07926    3 LSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQALREELNELKAEIAELKAEAES 82

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 119611609  1195 AESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1241
Cdd:pfam07926   83 AKAELEESEESWEEQKKELEKELSELEKRIEDLNEQNKLLHDQLESL 129
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 848-1694 4.08e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 4.08e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   848 KLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRL---SSQIEKLEHEIS 924
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   925 HLKKKLENEVEQRhtltRNLDVQLLDTKRQLD-TETNLHLNTKELlKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQP 1003
Cdd:TIGR02168  306 ILRERLANLERQL----EELEAQLEELESKLDeLAEELAELEEKL-EELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1004 SN--KEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLnkEKQVTEEVRKNIEVRLKESAEFQTQLEK 1081
Cdd:TIGR02168  381 LEtlRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQEELER 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1082 KLMEVEKEKQELqDDKRRAIESMEQQLSELKKTLSSVQNEVQEA--LQRASTALSNEQQARRDCQEQAKIAVEAQNKYER 1159
Cdd:TIGR02168  459 LEEALEELREEL-EEAEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1160 EL------MLHAADVEALQAAKEQVS---KMASVRQHLEETTQKAESQLleckaswEERERMLKDEVSKCVCRCEDLEKQ 1230
Cdd:TIGR02168  538 AIeaalggRLQAVVVENLNAAKKAIAflkQNELGRVTFLPLDSIKGTEI-------QGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1231 NRLLHDQIEKLSDKVVasVKEGVQGPLNVslseegksQEQILEILRFIRREKEIAETRFEVAqveslryrqrvellerel 1310
Cdd:TIGR02168  611 DPKLRKALSYLLGGVL--VVDDLDNALEL--------AKKLRPGYRIVTLDGDLVRPGGVIT------------------ 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1311 qelqdslnaeREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIlplqeanAELS 1390
Cdd:TIGR02168  663 ----------GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL-------EELS 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1391 EKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNN--- 1467
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrea 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1468 ----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKvmetsaqssgdHQE 1543
Cdd:TIGR02168  805 ldelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-----------LES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1544 QHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQD---LQDRTTQEEQLRQ 1619
Cdd:TIGR02168  874 ELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnLQERLSEEYSLTL 953

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1620 Q--------ITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvriTALKSQYEGRISRLERE 1691
Cdd:TIGR02168  954 EeaealenkIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDL----TEAKETLEEAIEEIDRE 1029


                   ...
gi 119611609  1692 LRE 1694
Cdd:TIGR02168 1030 ARE 1032
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-1141 6.78e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 6.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   302 ENKKEEVSRLEEqmnglktSNEHLQKhVEDLLTKLKEAK---EQQASMEEKFHnELNAHIK------LSNLYKSAADDSE 372
Cdd:TIGR02168  172 ERRKETERKLER-------TRENLDR-LEDILNELERQLkslERQAEKAERYK-ELKAELRelelalLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   373 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEqskdqmekEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 452
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVS--------ELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   453 MSPTAAAVAKIVKPGMKLTELynayvetqdQLLLEKLENKrinkyLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVK 532
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDEL---------AEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   533 LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhl 612
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE------------ 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   613 vsyrnIEELQQQNQRLLVALRELgetreREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSiVRQRDMYRIL 692
Cdd:TIGR02168  449 -----LEELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   693 LSQTTGVAIPLH--------------ASSLDDV---------SLASTPKRPSTSQTvsTPAPVPVIESTEAIEAKAALKQ 749
Cdd:TIGR02168  518 LSGILGVLSELIsvdegyeaaieaalGGRLQAVvvenlnaakKAIAFLKQNELGRV--TFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   750 LQEIFENYKKEKAE-NEKIQN------------EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQdnveGYRREITS 816
Cdd:TIGR02168  596 NIEGFLGVAKDLVKfDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITG----GSAKTNSS 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   817 LHERNQKLTATTQKQEQiintMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnlqt 896
Cdd:TIGR02168  672 ILERRREIEELEEKIEE----LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD------------- 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   897 iqgilersetetKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLhlntKELLKNAQKEI 976
Cdd:TIGR02168  735 ------------LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL----EAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   977 ATLKQHLS--NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-- 1052
Cdd:TIGR02168  799 KALREALDelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEal 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1053 -KEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQN-EVQEALQ 1127
Cdd:TIGR02168  879 lNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEA 958

                          890
                   ....*....|....
gi 119611609  1128 RASTALSNEQQARR 1141
Cdd:TIGR02168  959 LENKIEDDEEEARR 972
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 99-636 3.12e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.21  E-value: 3.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   99 NKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIA 178
Cdd:COG1196   249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  179 QDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKKRL 258
Cdd:COG1196   329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  259 EQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE 338
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  339 AKEQ---QASMEEKFHNELNAHIKLSNLyKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK 415
Cdd:COG1196   489 AAARlllLLEAEADYEGFLEGVKAALLL-AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLK 567

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  416 EmlEKIGRLEKELENANDLLSATKRKGAILSEEELAAmsptAAAVAKIVKPGMKLTELYNAYVETQDQLLLEkLENKRIN 495
Cdd:COG1196   568 A--AKAGRATFLPLDKIRARAALAAALARGAIGAAVD----LVASDLREADARYYVLGDTLLGRTLVAARLE-AALRRAV 640

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  496 KYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQI 575
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609  576 RVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYrNIEELQQQNQRLLVALRELG 636
Cdd:COG1196   721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP-DLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1428-1734 4.85e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 4.85e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1428 EYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASltnnqnlIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTIT 1507
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAE-------LEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1508 QVKKIGRRYKTQYEELKAQQDkvmETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEAR 1587
Cdd:COG1196   306 RLEERRRELEERLEELEEELA---ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1588 NLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEktrkAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQK 1667
Cdd:COG1196   383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE----ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609 1668 DELDVRITALKSQYEGRISRLERELREHQErhLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIA 1734
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
PTZ00121 PTZ00121
MAEBL; Provisional
 1005-1719 1.37e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.10  E-value: 1.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1005 NKEDVDDLVSQLRQTEEQVNDLkERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEfQTQLEKKLM 1084
Cdd:PTZ00121 1048 IDEDIDGNHEGKAEAKAHVGQD-EGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARK-AEEAKKKAE 1125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1085 EVEK-EKQELQDDKRRAIESMEQQlselkktlssvQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1163
Cdd:PTZ00121 1126 DARKaEEARKAEDARKAEEARKAE-----------DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELR 1194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1164 HAADVEALQAAK--EQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1241
Cdd:PTZ00121 1195 KAEDARKAEAARkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1242 SDKVVAsvkEGVQGPLNVSLSEEGKSQEQIleilrfiRREKEIAETRFEVAQVESLRYRQRVELLERELQELQdslnAER 1321
Cdd:PTZ00121 1275 EEARKA---DELKKAEEKKKADEAKKAEEK-------KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEE 1340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1322 EKVQVTAKTmAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLElDILPLQEANAELSEKSGMLQAEKK 1401
Cdd:PTZ00121 1341 AKKAAEAAK-AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD-EAKKKAEEDKKKADELKKAAAAKK 1418

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1402 LLEEDVKRWKARNQHLVSQQKdpdTEEYRKllsEKEVHTKRIQQLTEEIGRLKAEIARSnasltnnqnlIQSLKEDLNKV 1481
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKK---AEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK----------ADEAKKKAEEA 1482

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1482 RTEKETIQKDLDAKiiDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1561
Cdd:PTZ00121 1483 KKADEAKKKAEEAK--KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1562 ETKSKSLESQVENLQKTLSEKETE-ARNLQEQTVQLQSELSRLRQDL---QDRTTQEEQLRQQITEKEEKTRKAIVAAKS 1637
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMkaeEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1638 KIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQE-RHLEQRDEPQEPSNKVPEQ 1716
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEaKKAEELKKKEAEEKKKAEE 1720


                  ...
gi 119611609 1717 QRQ 1719
Cdd:PTZ00121 1721 LKK 1723
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
102-687 1.93e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 76.26  E-value: 1.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  102 EKFLADQQSEIDGLKGRHEKFKVESEqqyfEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdr 181
Cdd:PRK03918  164 YKNLGEVIKEIKRRIERLEKFIKRTE----NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE----- 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  182 niaiqsqftRTKEELEAEKRdlirtnerlsqELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQasdvsvkakkrlEQE 261
Cdd:PRK03918  235 ---------ELKEEIEELEK-----------ELESLEGSKRKLEEKIRELEERIEELKKEIEELE------------EKV 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  262 KELlhsqntwlnTELKTKTDELLALGREKgNEILELKCNLEnkkEEVSRLEEQMNGLktsnEHLQKHVEDLLTKLKEAKE 341
Cdd:PRK03918  283 KEL---------KELKEKAEEYIKLSEFY-EEYLDELREIE---KRLSRLEEEINGI----EERIKELEEKEERLEELKK 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  342 QQASMEEKFhNELNAHIKLSNLYKSAADDSEAKSNELT-RAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEmlek 420
Cdd:PRK03918  346 KLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE---- 420

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  421 igrlEKELENANDLLSATKRK----GAILSEE-ELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRIN 495
Cdd:PRK03918  421 ----IKELKKAIEELKKAKGKcpvcGRELTEEhRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  496 KYLD--EIVKEVEAK-----APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEdtdkANKQSSVLERDNRRMEIQV 568
Cdd:PRK03918  497 KLKElaEQLKELEEKlkkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE----LKKKLAELEKKLDELEEEL 572

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  569 KDLSQQIRVL-----------LMELEEARGNHV-IRDEEVSSADISSSSEVISQHLV-SYRNIEELQQQNQRLLVALREL 635
Cdd:PRK03918  573 AELLKELEELgfesveeleerLKELEPFYNEYLeLKDAEKELEREEKELKKLEEELDkAFEELAETEKRLEELRKELEEL 652

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 119611609  636 GETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRD 687
Cdd:PRK03918  653 EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 947-1759 1.86e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 73.23  E-value: 1.86e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   947 QLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLsNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLrqteEQVNDL 1026
Cdd:pfam15921   86 QVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM-QMERDAMADIRRRESQSQEDLRNQLQNTVHEL----EAAKCL 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1027 KE-RLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQT--------QLEKKLMEVEKEKQELQDdk 1097
Cdd:pfam15921  161 KEdMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTmhfrslgsAISKILRELDTEISYLKG-- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1098 rrAIESMEQQLSELKktlSSVQNEVQEALQ----RASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLhaadveALQA 1173
Cdd:pfam15921  239 --RIFPVEDQLEALK---SESQNKIELLLQqhqdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI------IQEQ 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1174 AKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLK-------DEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVV 1246
Cdd:pfam15921  308 ARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1247 ASVKE-GVQGPLNVSLSEEGKSQEQILEILRfirreKEIAETRFEVAQVESL--RYRQRVELLERELQELQDSLNAEREK 1323
Cdd:pfam15921  388 KREKElSLEKEQNKRLWDRDTGNSITIDHLR-----RELDDRNMEVQRLEALlkAMKSECQGQMERQMAAIQGKNESLEK 462

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1324 VQ-VTAKTMAQHEELMKKTETMNvvmeTNKMLREEKERLEQDLQ-QMQAKVRKLEldilplqEANAELSEksgmLQAEKK 1401
Cdd:pfam15921  463 VSsLTAQLESTKEMLRKVVEELT----AKKMTLESSERTVSDLTaSLQEKERAIE-------ATNAEITK----LRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1402 LLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ-----QLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1476
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQienmtQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ 607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1477 DLNKVRTEKETIQKDLDAKIIDIQ-EKVKTITqvkkigrrykTQYEELKAQQDKVMETSaqssgdhqeqhvsvQEMQELK 1555
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLElEKVKLVN----------AGSERLRAVKDIKQERD--------------QLLNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1556 ETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQ-------LRQQITEKeekt 1628
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHamkvamgMQKQITAK---- 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1629 RKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQ-------QKDELDVRITALKSQ---YEGRISRLERELREHQER 1698
Cdd:pfam15921  740 RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQelstvatEKNKMAGELEVLRSQerrLKEKVANMEVALDKASLQ 819

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609  1699 HLEQRDEPQEPSNKVPEQQRQITLKTTPASGErGIASTSDPPTANIKPTPVVSTPSKVTAA 1759
Cdd:pfam15921  820 FAECQDIIQRQEQESVRLKLQHTLDVKELQGP-GYTSNSSMKPRLLQPASFTRTHSNVPSS 879
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 234-1124 1.43e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 70.39  E-value: 1.43e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   234 TKGELQLKLDELQA-SDVSVKAKKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE 312
Cdd:pfam02463  150 MKPERRLEIEEEAAgSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   313 EQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEA 392
Cdd:pfam02463  230 DYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   393 GEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVkpgmKLTE 472
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEK-EEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK----LESE 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   473 LYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEakapILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANK 552
Cdd:pfam02463  385 RLSSAAKLKEEELELKSEEEKEAQLLLELARQLE----DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   553 QSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVAL 632
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   633 RELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQrdmYRILLSQTTGVAIPLHASSLDDVS 712
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS---IAVLEIDPILNLAQLDKATLEADE 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   713 LASTPKRPSTSQTVSTpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQ 792
Cdd:pfam02463  618 DDKRAKVVEGILKDTE-------LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   793 LDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEvraENLKKEKEMLKLSEVR 872
Cdd:pfam02463  691 KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   873 LSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTK 952
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   953 RQLDTETNLHLNTKELLKNAQKEIATLKQHLSN-MEVQVASQSSQRTGKGQpsnKEDVDDLVSQLRQTEEQVNDLKERLK 1031
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLLKEEELEeQKLKDELESKEEKEKEE---KKELEEESQKLNLLEEKENEIEERIK 924

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1032 TSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQdDKRRAIESMEQQLSEL 1111
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE-ERYNKDELEKERLEEE 1003

                          890
                   ....*....|...
gi 119611609  1112 KKTLSSVQNEVQE 1124
Cdd:pfam02463 1004 KKKLIRAIIEETC 1016
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
105-447 5.24e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  105 LADQQSEIDGLKGRHEKF------KVESEQQYFEIEKRLSHSQERL---------VNETRECQSLRLELEKLNNQLKALT 169
Cdd:COG4717    73 LKELEEELKEAEEKEEEYaelqeeLEELEEELEELEAELEELREELeklekllqlLPLYQELEALEAELAELPERLEELE 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  170 EKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDL----IRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDEL 245
Cdd:COG4717   153 ERLEELRELEEELEELEAELAELQEELEELLEQLslatEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  246 QASDVSVKAKKRLEQEKELL--------HSQNTWLNTELKTKTDELLALG---------------REKGNEILELKCNLE 302
Cdd:COG4717   233 ENELEAAALEERLKEARLLLliaaallaLLGLGGSLLSLILTIAGVLFLVlgllallflllarekASLGKEAEELQALPA 312

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  303 NKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH--NELNAHIKLSNLYKSAADDSEAKSNELTR 380
Cdd:COG4717   313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAEAGVEDEEELRAALE 392

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609  381 AVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML-EKIGRLEKEL-ENANDLLSATKRKGAILSE 447
Cdd:COG4717   393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEELeEELEELEEELeELEEELEELREELAELEAE 461
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 108-399 1.47e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   108 QQSEIDglkgRHEKFKVESEQQYFEIEK---RLSHSQERLVNETRECQSLRLELE-KLNNQLKALTEKNKELEIAQDRNI 183
Cdd:TIGR02168  675 RRREIE----ELEEKIEELEEKIAELEKalaELRKELEELEEELEQLRKELEELSrQISALRKDLARLEAEVEQLEERIA 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   184 AIQSQFTRTKEELEAEKRDLIRTNERLS---QELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS-DVSVKAKKRLE 259
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAeaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEaANLRERLESLE 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   260 QEKELLHSQNTWLNTELKTKTDELLALGRE---KGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKL 336
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119611609   337 KEAKEQQASMEEKFH------NELNAHI-----KLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAI 399
Cdd:TIGR02168  911 SELRRELEELREKLAqlelrlEGLEVRIdnlqeRLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
PRK11281 PRK11281
mechanosensitive channel MscK;
58-380 2.90e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 46.44  E-value: 2.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   58 FFSASTPSAAATGVPGPT--DMAAVLQQVLERTELNKLPKSVQNKLEKFLA------DQQSEIDGLKGRHEKFKVESEQQ 129
Cdd:PRK11281   20 LCLSSAFARAASNGDLPTeaDVQAQLDALNKQKLLEAEDKLVQQDLEQTLAlldkidRQKEETEQLKQQLAQAPAKLRQA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  130 YFEIEkRLSHSQERLVNETRECQSLRlELE-KLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEEL-EAEKRdlirtn 207
Cdd:PRK11281  100 QAELE-ALKDDNDEETRETLSTLSLR-QLEsRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALyANSQR------ 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  208 erlSQEleyltedvkrLNEKLKESNTTKGELqlkldelqasdvSVKAKKRLEQEKELLHSQNTWLNTELKTkTDELLALG 287
Cdd:PRK11281  172 ---LQQ----------IRNLLKGGKVGGKAL------------RPSQRVLLQAEQALLNAQNDLQRKSLEG-NTQLQDLL 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  288 REKGNEilelkcnlenKKEEVSRLEEQMNGLKT--SNEHL---QKHVEDLLTKLKEAKEQQASMeekFHNELNAHIKLSN 362
Cdd:PRK11281  226 QKQRDY----------LTARIQRLEHQLQLLQEaiNSKRLtlsEKTVQEAQSQDEAARIQANPL---VAQELEINLQLSQ 292

                         330
                  ....*....|....*...
gi 119611609  363 LYKSAADdseaKSNELTR 380
Cdd:PRK11281  293 RLLKATE----KLNTLTQ 306
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1724-1900 2.46e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 43.37  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1724 TTPASGERGIASTSDPPTAN-IKPTPVVSTPSKVTAAAMAGNKSTPRASIRPmvtpaTVTNPTTTPTATVMPTTQVESQE 1802
Cdd:pfam05109  535 TSPTLGKTSPTSAVTTPTPNaTSPTPAVTTPTPNATIPTLGKTSPTSAVTTP-----TPNATSPTVGETSPQANTTNHTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1803 AMQSEGPVEHVPVFGSTSG---------SVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHP-------QIEPAnq 1866
Cdd:pfam05109  610 GGTSSTPVVTSPPKNATSAvttgqhnitSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPtggenitQVTPA-- 687

                          170       180       190
                   ....*....|....*....|....*....|....
gi 119611609  1867 elSSNIVEVVQSSPVERPSTSTAVFGTVSATPSS 1900
Cdd:pfam05109  688 --STSTHHVSTSSPAPRPGTTSQASGPGNSSTST 719
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 81-429 4.40e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 4.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    81 LQQVLERTELNK--LPKSVQNkLEKFLADQQSEIDGL---KGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLR 155
Cdd:pfam01576  361 LTEQLEQAKRNKanLEKAKQA-LESENAELQAELRTLqqaKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQ 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   156 LELEKLNNQLKALTEKNKELeiaQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQeleyLTEDVKRLNEKLKESNTTK 235
Cdd:pfam01576  440 SELESVSSLLNEAEGKNIKL---SKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ----LEDERNSLQEQLEEEEEAK 512

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   236 GELQLKLDELQASdvSVKAKKRLEQEKELLhsqntwlntelktktdELLALGREKgneileLKCNLENKKEEVSRLEEQM 315
Cdd:pfam01576  513 RNVERQLSTLQAQ--LSDMKKKLEEDAGTL----------------EALEEGKKR------LQRELEALTQQLEEKAAAY 568

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   316 NGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK---FHNELNAHIKLSNLYKSAADDSEAKSNE-------LTRAVEEL 385
Cdd:pfam01576  569 DKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKqkkFDQMLAEEKAISARYAEERDRAEAEAREketralsLARALEEA 648

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 119611609   386 HKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM--LEKIGR-LEKELE 429
Cdd:pfam01576  649 LEAKEELERTNKQLRAEMEDLVSSKDDVGKNVheLERSKRaLEQQVE 695
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1014-1257 7.45e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 7.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1014 SQLRQTEEQVNDLKERLKTSTSNVEQYQamvtsleeslnKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQEL 1093
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALK-----------KEEKALLKQLAALERRIAALARRIRALEQELAALEAELAEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1094 QDDKRRAIESMEQQLSELKKTLSSVQ-NEVQEALQRASTALSNEQQARRdcQEQAKIAVEAQNKYERELmlhAADVEALQ 1172
Cdd:COG4942    89 EKEIAELRAELEAQKEELAELLRALYrLGRQPPLALLLSPEDFLDAVRR--LQYLKYLAPARREQAEEL---RADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1173 AAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEG 1252
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                  ....*
gi 119611609 1253 VQGPL 1257
Cdd:COG4942   244 PAAGF 248
PRK12704 PRK12704
phosphodiesterase; Provisional
 1049-1182 8.83e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 8.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1049 ESLNKEK--QVTEEVRK-----NIEVRLKESaEFQtQLEKKLMEVE---KEKQELQDDKRRAIESMEQQLSELKKTLSSV 1118
Cdd:PRK12704   52 EAIKKEAllEAKEEIHKlrnefEKELRERRN-ELQ-KLEKRLLQKEenlDRKLELLEKREEELEKKEKELEQKQQELEKK 129

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119611609 1119 QNEVQEALQRASTALsnEQQARRDcQEQAK--IAVEAQNKYERELMLHAADVEalQAAKEQVSKMA 1182
Cdd:PRK12704  130 EEELEELIEEQLQEL--ERISGLT-AEEAKeiLLEKVEEEARHEAAVLIKEIE--EEAKEEADKKA 190
 
Name Accession Description Interval E-value
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 1115-1241 4.13e-27

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 108.11  E-value: 4.13e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1115 LSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1194
Cdd:pfam07926    3 LSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQALREELNELKAEIAELKAEAES 82

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 119611609  1195 AESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1241
Cdd:pfam07926   83 AKAELEESEESWEEQKKELEKELSELEKRIEDLNEQNKLLHDQLESL 129
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 848-1694 4.08e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 4.08e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   848 KLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRL---SSQIEKLEHEIS 924
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   925 HLKKKLENEVEQRhtltRNLDVQLLDTKRQLD-TETNLHLNTKELlKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQP 1003
Cdd:TIGR02168  306 ILRERLANLERQL----EELEAQLEELESKLDeLAEELAELEEKL-EELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1004 SN--KEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLnkEKQVTEEVRKNIEVRLKESAEFQTQLEK 1081
Cdd:TIGR02168  381 LEtlRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQEELER 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1082 KLMEVEKEKQELqDDKRRAIESMEQQLSELKKTLSSVQNEVQEA--LQRASTALSNEQQARRDCQEQAKIAVEAQNKYER 1159
Cdd:TIGR02168  459 LEEALEELREEL-EEAEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1160 EL------MLHAADVEALQAAKEQVS---KMASVRQHLEETTQKAESQLleckaswEERERMLKDEVSKCVCRCEDLEKQ 1230
Cdd:TIGR02168  538 AIeaalggRLQAVVVENLNAAKKAIAflkQNELGRVTFLPLDSIKGTEI-------QGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1231 NRLLHDQIEKLSDKVVasVKEGVQGPLNVslseegksQEQILEILRFIRREKEIAETRFEVAqveslryrqrvellerel 1310
Cdd:TIGR02168  611 DPKLRKALSYLLGGVL--VVDDLDNALEL--------AKKLRPGYRIVTLDGDLVRPGGVIT------------------ 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1311 qelqdslnaeREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIlplqeanAELS 1390
Cdd:TIGR02168  663 ----------GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL-------EELS 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1391 EKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNN--- 1467
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrea 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1468 ----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKvmetsaqssgdHQE 1543
Cdd:TIGR02168  805 ldelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-----------LES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1544 QHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQD---LQDRTTQEEQLRQ 1619
Cdd:TIGR02168  874 ELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnLQERLSEEYSLTL 953

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1620 Q--------ITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvriTALKSQYEGRISRLERE 1691
Cdd:TIGR02168  954 EeaealenkIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDL----TEAKETLEEAIEEIDRE 1029


                   ...
gi 119611609  1692 LRE 1694
Cdd:TIGR02168 1030 ARE 1032
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 860-1724 1.72e-22

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 106.31  E-value: 1.72e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   860 KKEKEMLKLSEVRLSQQRESLLAEQRGQNLlltnlQTIQGilERSETETKQRLSSQIEKLE-HEISHLKKKLENEVEQRH 938
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQL-----ERLRR--EREKAERYQALLKEKREYEgYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   939 TLTRNLDVQLLDTKRQLD--------TETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQrtgkgQPSNKEDVD 1010
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISelekrleeIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS-----IAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1011 DLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEvrlKESAEFQTqLEKKLMEVEKEK 1090
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE---EVDKEFAE-TRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1091 QELQDdKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKiaveaqnKYERELMLHAADVEA 1170
Cdd:TIGR02169  395 EKLKR-EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK-------KQEWKLEQLAADLSK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1171 lqaAKEQVSKMASVRQHLEETTQKAESQLLECKAS---WEERERMLKDEVskcvcrcEDLEKQNRLLHDQIEKLsdkvvA 1247
Cdd:TIGR02169  467 ---YEQELYDLKEEYDRVEKELSKLQRELAEAEAQaraSEERVRGGRAVE-------EVLKASIQGVHGTVAQL-----G 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1248 SVKEGVQGPL---------NVSLSEEGKSQEQIleilRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLN 1318
Cdd:TIGR02169  532 SVGERYATAIevaagnrlnNVVVEDDAVAKEAI----ELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1319 AEReKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQD--LQQMQAKVRKLELDILPLQEANAELSEKSGML 1396
Cdd:TIGR02169  608 FDP-KYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1397 QAEKKLLEEDVKRWKARnqhlvsqqkdpdTEEYRKLLSEKEvhtKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1476
Cdd:TIGR02169  687 KRELSSLQSELRRIENR------------LDELSQELSDAS---RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1477 DLNKVRTEKETIQKDLD---AKIIDIQEKVKTI------TQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVS 1547
Cdd:TIGR02169  752 EIENVKSELKELEARIEeleEDLHKLEEALNDLearlshSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1548 VQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEK 1627
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1628 TRKAIVAAKSKIAHLAGVKDQLTKENEELKQRN---------GALDQQKDELDVRITALKS-------QYEGRISRLErE 1691
Cdd:TIGR02169  912 IEKKRKRLSELKAKLEALEEELSEIEDPKGEDEeipeeelslEDVQAELQRVEEEIRALEPvnmlaiqEYEEVLKRLD-E 990

                          890       900       910
                   ....*....|....*....|....*....|...
gi 119611609  1692 LREHQERHLEQRDEPQEPSNKVPEQQRQITLKT 1724
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 747-1528 4.94e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.74  E-value: 4.94e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   747 LKQLQEIFENYKKEKAENEKIQNE---QLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQK 823
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEEltaELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   824 LTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILER 903
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   904 SETETK---QRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTK-ELLKNAQKEIATL 979
Cdd:TIGR02168  394 QIASLNneiERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLeEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   980 KQHLSNMEVQVASQSSQRTG-KGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQY-QAMVTSLEESLNKEKQV 1057
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYeAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1058 TEE-VRKNIEVRLKESAEFQTQLEKKLMEvEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTA--LS 1134
Cdd:TIGR02168  554 NLNaAKKAIAFLKQNELGRVTFLPLDSIK-GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVddLD 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1135 NEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERmLK 1214
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEE-LE 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1215 DEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVvasvkEGVQGPLNVSLSEEGKSQEQILEilrfIRREKEIAETRFEVAQV 1294
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEV-----EQLEERIAQLSKELTELEAEIEE----LEERLEEAEEELAEAEA 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1295 ESLRYRQRVELLERELQELQDSLNAEREKVQvtaktmAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRK 1374
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELT------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1375 LELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLK 1454
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE-SKRSELRRELEELREKLAQLELRLEGLE 935

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 119611609  1455 AEIARSNASLTNNQNLiqSLKEDLNKVRtEKETIQKDLDAKIIDIQEKVKTITQVKKIG----RRYKTQYEELKAQQD 1528
Cdd:TIGR02168  936 VRIDNLQERLSEEYSL--TLEEAEALEN-KIEDDEEEARRRLKRLENKIKELGPVNLAAieeyEELKERYDFLTAQKE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-1141 6.78e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 6.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   302 ENKKEEVSRLEEqmnglktSNEHLQKhVEDLLTKLKEAK---EQQASMEEKFHnELNAHIK------LSNLYKSAADDSE 372
Cdd:TIGR02168  172 ERRKETERKLER-------TRENLDR-LEDILNELERQLkslERQAEKAERYK-ELKAELRelelalLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   373 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEqskdqmekEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 452
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVS--------ELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   453 MSPTAAAVAKIVKPGMKLTELynayvetqdQLLLEKLENKrinkyLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVK 532
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDEL---------AEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   533 LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhl 612
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE------------ 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   613 vsyrnIEELQQQNQRLLVALRELgetreREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSiVRQRDMYRIL 692
Cdd:TIGR02168  449 -----LEELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   693 LSQTTGVAIPLH--------------ASSLDDV---------SLASTPKRPSTSQTvsTPAPVPVIESTEAIEAKAALKQ 749
Cdd:TIGR02168  518 LSGILGVLSELIsvdegyeaaieaalGGRLQAVvvenlnaakKAIAFLKQNELGRV--TFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   750 LQEIFENYKKEKAE-NEKIQN------------EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQdnveGYRREITS 816
Cdd:TIGR02168  596 NIEGFLGVAKDLVKfDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITG----GSAKTNSS 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   817 LHERNQKLTATTQKQEQiintMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnlqt 896
Cdd:TIGR02168  672 ILERRREIEELEEKIEE----LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD------------- 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   897 iqgilersetetKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLhlntKELLKNAQKEI 976
Cdd:TIGR02168  735 ------------LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL----EAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   977 ATLKQHLS--NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-- 1052
Cdd:TIGR02168  799 KALREALDelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEal 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1053 -KEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQN-EVQEALQ 1127
Cdd:TIGR02168  879 lNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEA 958

                          890
                   ....*....|....
gi 119611609  1128 RASTALSNEQQARR 1141
Cdd:TIGR02168  959 LENKIEDDEEEARR 972
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1049-1715 1.12e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 1.12e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1049 ESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQ---DDKRRAIESMEQQLSELKKTLSSVQNEVQEA 1125
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkelYALANEISRLEQQKQILRERLANLERQLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1126 LQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKeqvSKMASVRQHLEeTTQKAESQLLECKAS 1205
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE---SRLEELEEQLE-TLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1206 WEERERMLKDEVskcvcrcEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGplnvSLSEEGKSQEQILEILRFIRREKEIA 1285
Cdd:TIGR02168  398 LNNEIERLEARL-------ERLEDRRERLQQEIEELLKKLEEAELKELQA----ELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1286 ETRFEVAQVESL-------RYRQRVELLERELQELQDSLNAEREKVQVtAKTMAQH-----------EELMKKTETM--- 1344
Cdd:TIGR02168  467 REELEEAEQALDaaerelaQLQARLDSLERLQENLEGFSEGVKALLKN-QSGLSGIlgvlselisvdEGYEAAIEAAlgg 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1345 ---NVVMETNKMLREEKERLEQDLqqmQAKVRKLELDILPLQEANAE----LSEKSGMLQAEKKLLEEDVKRWKARN--- 1414
Cdd:TIGR02168  546 rlqAVVVENLNAAKKAIAFLKQNE---LGRVTFLPLDSIKGTEIQGNdreiLKNIEGFLGVAKDLVKFDPKLRKALSyll 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1415 -QHLVSQQKDPDTEEYRKLLSEKEVHT---------------------------KRIQQLTEEIGRLKAEIARSNASLTN 1466
Cdd:TIGR02168  623 gGVLVVDDLDNALELAKKLRPGYRIVTldgdlvrpggvitggsaktnssilerrREIEELEEKIEELEEKIAELEKALAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1467 NQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKkigRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHV 1546
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE---ERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1547 SVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKE- 1625
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAa 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1626 --EKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALK----------SQYEGRISRLERELR 1693
Cdd:TIGR02168  860 eiEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRreleelreklAQLELRLEGLEVRID 939

                          730       740
                   ....*....|....*....|...
gi 119611609  1694 EHQERHLEQ-RDEPQEPSNKVPE 1715
Cdd:TIGR02168  940 NLQERLSEEySLTLEEAEALENK 962
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 907-1719 5.80e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 5.80e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   907 ETKQRLSSQIEKLEHEISHLKKKLeNEVEQRHTLTRNLDVQLLDTKRQLDTETNlhlNTKELLKNAQKEIATLKQHLSNM 986
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAEL-QELEEKLEELRLEVSELEEEIEELQKELY---ALANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   987 EVQVASQSSQRTGKGQPSN--KEDVDDLVSQLRQTEEQVNDLKERLKTStsnVEQYQAMVTSLEEslnKEKQVTEEVRKN 1064
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDelAEELAELEEKLEELKEELESLEAELEEL---EAELEELESRLEE---LEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1065 IEVRLKEsaefqTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL----KKTLSSVQNEVQEALQRASTALSNEQQAR 1140
Cdd:TIGR02168  389 AQLELQI-----ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLeeaeLKELQAELEELEEELEELQEELERLEEAL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1141 RDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMA-SVRQHLEETTQKAE-----SQLLECKASWE-ERERML 1213
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSeGVKALLKNQSGLSGilgvlSELISVDEGYEaAIEAAL 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1214 KDEVSKCVCrcEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGP-LNVSLSEEGKSQEQILEILRfirrEKEIAETRFEVA 1292
Cdd:TIGR02168  544 GGRLQAVVV--ENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTeIQGNDREILKNIEGFLGVAK----DLVKFDPKLRKA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1293 qVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKT-ETMNVVMETNKmlreEKERLEQDLQQMQAK 1371
Cdd:TIGR02168  618 -LSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSaKTNSSILERRR----EIEELEEKIEELEEK 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1372 VRKLEldilplqeanAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDpdteeYRKLLSEKEVHTKRIQQLTEEIG 1451
Cdd:TIGR02168  693 IAELE----------KALAELRKELEELEEELEQLRKELEELSRQISALRKD-----LARLEAEVEQLEERIAQLSKELT 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1452 RLKAEIArsnasltnnqnliqSLKEDLNKVRTEKETIQKDLdakiidiqekvktitqvkkigrryktqyEELKAQQDKVM 1531
Cdd:TIGR02168  758 ELEAEIE--------------ELEERLEEAEEELAEAEAEI----------------------------EELEAQIEQLK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1532 ETSAQSSGDHQEQHvsvQEMQELKETLNQAETKskslesqVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1611
Cdd:TIGR02168  796 EELKALREALDELR---AELTLLNEEAANLRER-------LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1612 TQEEQLRQQITEKEEKTRKAIVAAKSKIAHLagvkDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEG---RISRL 1688
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGlevRIDNL 941

                          810       820       830
                   ....*....|....*....|....*....|.
gi 119611609  1689 ERELREHQErhLEQRDEPQEPSNKVPEQQRQ 1719
Cdd:TIGR02168  942 QERLSEEYS--LTLEEAEALENKIEDDEEEA 970
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 132-1128 1.15e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.03  E-value: 1.15e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   132 EIEKRLSHSQERLVnetrecqslRLE--LEKLNNQLKAL------TEKNKELEiAQDRNIAIQSQFTRtKEELEAEKRDL 203
Cdd:TIGR02168  176 ETERKLERTRENLD---------RLEdiLNELERQLKSLerqaekAERYKELK-AELRELELALLVLR-LEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   204 IRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKK-RLEQEKELLHSQNTWLNTELKTKTDE 282
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIsRLEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   283 LLALGREKgneilelkcnlENKKEEVSRLEEqmnglktsnehlqkhvedlltKLKEAKEQQASMEEKFhnelnahiklsn 362
Cdd:TIGR02168  325 LEELESKL-----------DELAEELAELEE---------------------KLEELKEELESLEAEL------------ 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   363 lyksaaddseaksneltravEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEmlekIGRLEKELENANDLLSATKRKG 442
Cdd:TIGR02168  361 --------------------EELEAELEELESRLEELEEQLETLRSKVAQLELQ----IASLNNEIERLEARLERLEDRR 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   443 AILSEEelaamsptaaavakivkpgmkLTELYNAYVETQDQLLLEKLEnkRINKYLDEIVKEVEAKAPILKRQREEYERA 522
Cdd:TIGR02168  417 ERLQQE---------------------IEELLKKLEEAELKELQAELE--ELEEELEELQEELERLEEALEELREELEEA 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   523 QKAVASLSVKLEQAMKEI---QRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRV-------LLMELEEARGNHVIR 592
Cdd:TIGR02168  474 EQALDAAERELAQLQARLdslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVdegyeaaIEAALGGRLQAVVVE 553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   593 DEEVssadISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSkitelqlkLESALTELEQLRKSR 672
Cdd:TIGR02168  554 NLNA----AKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD--------LVKFDPKLRKALSYL 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   673 QHQMQLVDSIVRQRDMYRILLSQTTGVaiplhasSLDDVSLastpkrpsTSQTVSTPAPVPVIESTeaIEAKAALKQLQE 752
Cdd:TIGR02168  622 LGGVLVVDDLDNALELAKKLRPGYRIV-------TLDGDLV--------RPGGVITGGSAKTNSSI--LERRREIEELEE 684

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   753 IFEnykkEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQE 832
Cdd:TIGR02168  685 KIE----ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   833 QIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLsevRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETK--- 909
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRERLESLERRIAate 837

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   910 ---QRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLldtkrqldtetnlhlntkELLKNAQKEIATLKQHLSNM 986
Cdd:TIGR02168  838 rrlEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL------------------NERASLEEALALLRSELEEL 899

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   987 EVQVASQSSQRtgkgqpsnkedvDDLVSQLRQTEEQVNDLKERLktstsnvEQYQAMVTSLEESLNKEKQVTEEVRKNIE 1066
Cdd:TIGR02168  900 SEELRELESKR------------SELRRELEELREKLAQLELRL-------EGLEVRIDNLQERLSEEYSLTLEEAEALE 960

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119611609  1067 VRLKESAEfqtQLEKKLMEVEKEKQELQDDKRRAIESMEqQLSELKKTLSSVQNEVQEALQR 1128
Cdd:TIGR02168  961 NKIEDDEE---EARRRLKRLENKIKELGPVNLAAIEEYE-ELKERYDFLTAQKEDLTEAKET 1018
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 742-1703 2.18e-15

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 83.17  E-value: 2.18e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   742 EAKAALKQLQEIFENYKKEKAEN--EKIQNEQLEKLQEQVTDLR------SQNTKISTQLDFASKRYEMLQDNVEGYRRE 813
Cdd:TIGR00606  167 EGKALKQKFDEIFSATRYIKALEtlRQVRQTQGQKVQEHQMELKylkqykEKACEIRDQITSKEAQLESSREIVKSYENE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   814 ITSLHERNQKLTATTQKQEQIINTMTQdlrganekLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTN 893
Cdd:TIGR00606  247 LDPLKNRLKEIEHNLSKIMKLDNEIKA--------LKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   894 LQTIQGILERSETETKQRLSSQiEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELlknaq 973
Cdd:TIGR00606  319 RELVDCQRELEKLNKERRLLNQ-EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQI----- 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   974 KEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK 1053
Cdd:TIGR00606  393 KNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDR 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1054 EKQVTEEVRKNI-EVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQqLSELKKTLSSVQNEVQEALQRASTA 1132
Cdd:TIGR00606  473 ILELDQELRKAErELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQ-LNHHTTTRTQMEMLTKDKMDKDEQI 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1133 LSNEQQARRDCQEQAKiavEAQNKYERELMLHAADVEALQAaKEQVSKMASVRQHLEETTQKAESQLleckASWEERERM 1212
Cdd:TIGR00606  552 RKIKSRHSDELTSLLG---YFPNKKQLEDWLHSKSKEINQT-RDRLAKLNKELASLEQNKNHINNEL----ESKEEQLSS 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1213 LKDEVSKcVCRCEDLEKQNRLLHDQIEKLS-DKVVASVKEGVQGPLNVSLSEEGKSQEQILEilRFIRREKEIAETrfev 1291
Cdd:TIGR00606  624 YEDKLFD-VCGSQDEESDLERLKEEIEKSSkQRAMLAGATAVYSQFITQLTDENQSCCPVCQ--RVFQTEAELQEF---- 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1292 aqVESLRYRQRVELLERELQELQDSlNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQak 1371
Cdd:TIGR00606  697 --ISDLQSKLRLAPDKLKSTESELK-KKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQE-- 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1372 vrKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIG 1451
Cdd:TIGR00606  772 --TLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNR 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1452 RLKAEiarsnasltnNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEEL----KAQQ 1527
Cdd:TIGR00606  850 KLIQD----------QQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDspleTFLE 919

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1528 DKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQV-ENLQKTLSEKETEARNL-------QEQTVQLQSE 1599
Cdd:TIGR00606  920 KDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIqDGKDDYLKQKETELNTVnaqleecEKHQEKINED 999

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1600 LSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDElDVRITALKS 1679
Cdd:TIGR00606 1000 MRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRN-HVLALGRQK 1078

                          970       980
                   ....*....|....*....|....
gi 119611609  1680 QYEGRISRLERELREHQERHLEQR 1703
Cdd:TIGR00606 1079 GYEKEIKHFKKELREPQFRDAEEK 1102
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 746-1413 4.64e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 4.64e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   746 ALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 825
Cdd:TIGR02168  292 ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   826 ATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQrgQNLLLTNLQTIQGILERSE 905
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEEL 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   906 TETKQRLSSQIEKLEhEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNaQKEIATLKQHLSN 985
Cdd:TIGR02168  450 EELQEELERLEEALE-ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN-QSGLSGILGVLSE 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   986 -----------MEVQVASQSSQRTGKGQPSNKEDVDDL------------VSQLRQTEEQVNDL-----KERLKTSTSNV 1037
Cdd:TIGR02168  528 lisvdegyeaaIEAALGGRLQAVVVENLNAAKKAIAFLkqnelgrvtflpLDSIKGTEIQGNDReilknIEGFLGVAKDL 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1038 EQYQ--------------AMVTSLEESLNKEKQVTEEVR---------------------------------KNIEVRLK 1070
Cdd:TIGR02168  608 VKFDpklrkalsyllggvLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktnssilerrreiEELEEKIE 687

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1071 ESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQNEVQEALQRastalsNEQQARRDCQEQA 1147
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEeleQLRKELEELSRQISALRKDLARLEAEVEQLEER------IAQLSKELTELEA 761

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1148 KIAVEAQNKYERELMLHAADVEaLQAAKEQVSKMASVRQHLEETTQKAESQLLECKasweERERMLKDEVSKCVCRCEDL 1227
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAELTLLN----EEAANLRERLESLERRIAAT 836

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1228 EKQNRLLHDQIEKLSDKVVAsvkegvqgpLNVSLSEEGKSQEQIleilrfirrEKEIAETRFEVAQVESLRYRQRvelle 1307
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIES---------LAAEIEELEELIEEL---------ESELEALLNERASLEEALALLR----- 893

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1308 relqelqdslnaerekvqvtaktmaqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEA-N 1386
Cdd:TIGR02168  894 ---------------------------SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlS 946

                          730       740
                   ....*....|....*....|....*..
gi 119611609  1387 AELSEKSGMLQAEKKLLEEDVKRWKAR 1413
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEARRR 973
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 158-1039 7.02e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 7.02e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   158 LEKLNNQLKALTEKNKELEiAQDRNIAIQSQFTRTKEELEAEKRDLirtnerlsqELEYLTEDVKRLNEKLKESNTTKGE 237
Cdd:TIGR02168  181 LERTRENLDRLEDILNELE-RQLKSLERQAEKAERYKELKAELREL---------ELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   238 LQLKLDELQAsdvsvkAKKRLEQEKELLHSQNTWLNTELKTKTDELLALGrekgNEILELKCNLENKKEEVSRLEEQMNG 317
Cdd:TIGR02168  251 AEEELEELTA------ELQELEEKLEELRLEVSELEEEIEELQKELYALA----NEISRLEQQKQILRERLANLERQLEE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   318 LKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANK 397
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   398 AIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAY 477
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   478 VETQDQL-----LLEKLENK--RINKYLDEIVKEVEAKAPILKRQ------REEYERAQKAVAS------LSVKLEQAMK 538
Cdd:TIGR02168  481 ERELAQLqarldSLERLQENleGFSEGVKALLKNQSGLSGILGVLselisvDEGYEAAIEAALGgrlqavVVENLNAAKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   539 EIQRLQEDtdKANKQSSVLERDNRRMEIQVKDLSQqirvlLMELEEARG---NHVIRDEEVSSadisssseVISQHLVSY 615
Cdd:TIGR02168  561 AIAFLKQN--ELGRVTFLPLDSIKGTEIQGNDREI-----LKNIEGFLGvakDLVKFDPKLRK--------ALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   616 RNIEELQQQNQRL--------LVAL-----------------RELGETREREEQETTSSKITELQLKLESALTELEQLRK 670
Cdd:TIGR02168  626 LVVDDLDNALELAkklrpgyrIVTLdgdlvrpggvitggsakTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   671 SRQHQMQLVDSIVRQRDMYRILLSQTtgvaiplhasslddvsLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQL 750
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISAL----------------RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   751 QEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQK 830
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   831 QEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNL-------LLTNLQTIQGILER 903
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESkrselrrELEELREKLAQLEL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   904 SETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLntkellkNAQKEIATLKQHL 983
Cdd:TIGR02168  930 RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNL-------AAIEEYEELKERY 1002

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609   984 SNMEVQvasqssqrtgkgqpsnKEDVDDLVSQLRQTEEQVND-LKERLKTSTSNVEQ 1039
Cdd:TIGR02168 1003 DFLTAQ----------------KEDLTEAKETLEEAIEEIDReARERFKDTFDQVNE 1043
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 488-1249 2.55e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.55e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   488 KLENKRIN-KYLDEIVKEVEAKAPILKRQ----------REEYERAQKAVASLSvkLEQAMKEIQRLQEDTDKANKQSSV 556
Cdd:TIGR02168  180 KLERTRENlDRLEDILNELERQLKSLERQaekaerykelKAELRELELALLVLR--LEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   557 LERDNRRMEIQVKDLSQQIRVLLMELEEARG---NHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALR 633
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKelyALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   634 ELgetrereeqETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTgvaiplhassLDDVSL 713
Cdd:TIGR02168  338 EL---------AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE----------LQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   714 ASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQ------NEQLEKLQEQVTDLRSQNT 787
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQeelerlEEALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   788 KISTQLDFASKRYEMLQD---NVEGYRREITSLHERNQKLTATTQKQEQIINT-------MTQDLRGANEKLAV----AE 853
Cdd:TIGR02168  479 AAERELAQLQARLDSLERlqeNLEGFSEGVKALLKNQSGLSGILGVLSELISVdegyeaaIEAALGGRLQAVVVenlnAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   854 VRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQnlLLTNLQTIQGILERSETeTKQRLSSQIEKLeheISHLK--KKLE 931
Cdd:TIGR02168  559 KKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDRE--ILKNIEGFLGVAKDLVK-FDPKLRKALSYL---LGGVLvvDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   932 NEVEQRHTLTRNLDVQLLD----------TKRQLDTETNLhLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKg 1001
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDgdlvrpggviTGGSAKTNSSI-LERRREIEELEEKIEELEEKIAELEKALAELRKELEEL- 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1002 qpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEvrlkesaefqtQLEK 1081
Cdd:TIGR02168  711 ----EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE-----------EAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1082 KLMEVEKEKQELQDDkrraIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERel 1161
Cdd:TIGR02168  776 ELAEAEAEIEELEAQ----IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE-- 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1162 mlhaadvealqaAKEQVSKMASVRQHLEETTQKAESQL---LECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQI 1238
Cdd:TIGR02168  850 ------------LSEDIESLAAEIEELEELIEELESELealLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810
                   ....*....|.
gi 119611609  1239 EKLSDKVVASV 1249
Cdd:TIGR02168  918 EELREKLAQLE 928
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 99-636 3.12e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.21  E-value: 3.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   99 NKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIA 178
Cdd:COG1196   249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  179 QDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKKRL 258
Cdd:COG1196   329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  259 EQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKE 338
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  339 AKEQ---QASMEEKFHNELNAHIKLSNLyKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK 415
Cdd:COG1196   489 AAARlllLLEAEADYEGFLEGVKAALLL-AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLK 567

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  416 EmlEKIGRLEKELENANDLLSATKRKGAILSEEELAAmsptAAAVAKIVKPGMKLTELYNAYVETQDQLLLEkLENKRIN 495
Cdd:COG1196   568 A--AKAGRATFLPLDKIRARAALAAALARGAIGAAVD----LVASDLREADARYYVLGDTLLGRTLVAARLE-AALRRAV 640

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  496 KYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQI 575
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609  576 RVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYrNIEELQQQNQRLLVALRELG 636
Cdd:COG1196   721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP-DLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1428-1734 4.85e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 4.85e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1428 EYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASltnnqnlIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTIT 1507
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAE-------LEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1508 QVKKIGRRYKTQYEELKAQQDkvmETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEAR 1587
Cdd:COG1196   306 RLEERRRELEERLEELEEELA---ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1588 NLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEktrkAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQK 1667
Cdd:COG1196   383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE----ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609 1668 DELDVRITALKSQYEGRISRLERELREHQErhLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIA 1734
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 742-1405 5.32e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 5.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  742 EAKAALK--QLQEIFENYKKEKAENE-KIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLH 818
Cdd:COG1196   208 QAEKAERyrELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  819 ERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQrgqnllltnlqtiq 898
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL-------------- 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  899 gilersetetkqrlssqiEKLEHEISHLKKKLENEVEQRHTLTRnldvQLLDTKRQLDTETNLHLNTKELLKNAQKEIAT 978
Cdd:COG1196   354 ------------------EEAEAELAEAEEALLEAEAELAEAEE----ELEELAEELLEALRAAAELAAQLEELEEAEEA 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  979 LKQHLSNMEvqvasqssqrtgkgqpsnkEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVT 1058
Cdd:COG1196   412 LLERLERLE-------------------EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1059 EEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQ 1138
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1139 ARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRqhleettqkaESQLLECKASWEERERMLKDEVS 1218
Cdd:COG1196   553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA----------AVDLVASDLREADARYYVLGDTL 622

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1219 KCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLR 1298
Cdd:COG1196   623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1299 YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKL--- 1375
Cdd:COG1196   703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpv 782

                         650       660       670
                  ....*....|....*....|....*....|....*.
gi 119611609 1376 ------ELDIlpLQEANAELSEKSGMLQAEKKLLEE 1405
Cdd:COG1196   783 nllaieEYEE--LEERYDFLSEQREDLEEARETLEE 816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 910-1459 1.00e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  910 QRLSSQIEKLEHEISHLKKkleneveqrhtltRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQ 989
Cdd:COG1196   216 RELKEELKELEAELLLLKL-------------RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  990 VASQssqrtgkgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVR---KNIE 1066
Cdd:COG1196   283 LEEA------------QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEeelEEAE 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1067 VRLKESAEFQTQLEKKLMEVEK---EKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDC 1143
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAelaEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1144 QEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKAS-WEERERMLKDEVSKCVC 1222
Cdd:COG1196   431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARlLLLLEAEADYEGFLEGV 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1223 RCEDLEKQNRLLHDQI------EKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQIL----------------EILRFIRR 1280
Cdd:COG1196   511 KAALLLAGLRGLAGAVavligvEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkaakagratflpldkiRARAALAA 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1281 EKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAERE----------KVQVTAKTMAQHEELMKKTETMNVVMET 1350
Cdd:COG1196   591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLeaalrravtlAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1351 NKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYR 1430
Cdd:COG1196   671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                         570       580
                  ....*....|....*....|....*....
gi 119611609 1431 KLLSEKEVhTKRIQQLTEEIGRLKAEIAR 1459
Cdd:COG1196   751 EALEELPE-PPDLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 1005-1719 1.37e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.10  E-value: 1.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1005 NKEDVDDLVSQLRQTEEQVNDLkERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEfQTQLEKKLM 1084
Cdd:PTZ00121 1048 IDEDIDGNHEGKAEAKAHVGQD-EGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARK-AEEAKKKAE 1125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1085 EVEK-EKQELQDDKRRAIESMEQQlselkktlssvQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1163
Cdd:PTZ00121 1126 DARKaEEARKAEDARKAEEARKAE-----------DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELR 1194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1164 HAADVEALQAAK--EQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1241
Cdd:PTZ00121 1195 KAEDARKAEAARkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1242 SDKVVAsvkEGVQGPLNVSLSEEGKSQEQIleilrfiRREKEIAETRFEVAQVESLRYRQRVELLERELQELQdslnAER 1321
Cdd:PTZ00121 1275 EEARKA---DELKKAEEKKKADEAKKAEEK-------KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEE 1340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1322 EKVQVTAKTmAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLElDILPLQEANAELSEKSGMLQAEKK 1401
Cdd:PTZ00121 1341 AKKAAEAAK-AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD-EAKKKAEEDKKKADELKKAAAAKK 1418

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1402 LLEEDVKRWKARNQHLVSQQKdpdTEEYRKllsEKEVHTKRIQQLTEEIGRLKAEIARSnasltnnqnlIQSLKEDLNKV 1481
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKK---AEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK----------ADEAKKKAEEA 1482

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1482 RTEKETIQKDLDAKiiDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1561
Cdd:PTZ00121 1483 KKADEAKKKAEEAK--KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1562 ETKSKSLESQVENLQKTLSEKETE-ARNLQEQTVQLQSELSRLRQDL---QDRTTQEEQLRQQITEKEEKTRKAIVAAKS 1637
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMkaeEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1638 KIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQE-RHLEQRDEPQEPSNKVPEQ 1716
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEaKKAEELKKKEAEEKKKAEE 1720


                  ...
gi 119611609 1717 QRQ 1719
Cdd:PTZ00121 1721 LKK 1723
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
102-687 1.93e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 76.26  E-value: 1.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  102 EKFLADQQSEIDGLKGRHEKFKVESEqqyfEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdr 181
Cdd:PRK03918  164 YKNLGEVIKEIKRRIERLEKFIKRTE----NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE----- 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  182 niaiqsqftRTKEELEAEKRdlirtnerlsqELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQasdvsvkakkrlEQE 261
Cdd:PRK03918  235 ---------ELKEEIEELEK-----------ELESLEGSKRKLEEKIRELEERIEELKKEIEELE------------EKV 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  262 KELlhsqntwlnTELKTKTDELLALGREKgNEILELKCNLEnkkEEVSRLEEQMNGLktsnEHLQKHVEDLLTKLKEAKE 341
Cdd:PRK03918  283 KEL---------KELKEKAEEYIKLSEFY-EEYLDELREIE---KRLSRLEEEINGI----EERIKELEEKEERLEELKK 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  342 QQASMEEKFhNELNAHIKLSNLYKSAADDSEAKSNELT-RAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEmlek 420
Cdd:PRK03918  346 KLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE---- 420

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  421 igrlEKELENANDLLSATKRK----GAILSEE-ELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRIN 495
Cdd:PRK03918  421 ----IKELKKAIEELKKAKGKcpvcGRELTEEhRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  496 KYLD--EIVKEVEAK-----APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEdtdkANKQSSVLERDNRRMEIQV 568
Cdd:PRK03918  497 KLKElaEQLKELEEKlkkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE----LKKKLAELEKKLDELEEEL 572

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  569 KDLSQQIRVL-----------LMELEEARGNHV-IRDEEVSSADISSSSEVISQHLV-SYRNIEELQQQNQRLLVALREL 635
Cdd:PRK03918  573 AELLKELEELgfesveeleerLKELEPFYNEYLeLKDAEKELEREEKELKKLEEELDkAFEELAETEKRLEELRKELEEL 652

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 119611609  636 GETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRD 687
Cdd:PRK03918  653 EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 112-695 3.40e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.74  E-value: 3.40e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  112 IDGLKGRHEKFKVESEQ--QYFEIEKRLshsqerlvnETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQF 189
Cdd:COG1196   195 LGELERQLEPLERQAEKaeRYRELKEEL---------KELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  190 TRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAsdvsvkAKKRLEQEKEllhsqn 269
Cdd:COG1196   266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE------ELAELEEELE------ 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  270 twlntELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK 349
Cdd:COG1196   334 -----ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  350 FHNELNAHIKLsnlyKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEkigrLEKELE 429
Cdd:COG1196   409 EEALLERLERL----EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL----LEAALA 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  430 NANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYnAYVETQDQLLLEKLENKRINKYLDEIVKEVE--A 507
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA-VAVLIGVEAAYEAALEAALAAALQNIVVEDDevA 559

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  508 KAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMEleeaRG 587
Cdd:COG1196   560 AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE----AA 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  588 NHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQ 667
Cdd:COG1196   636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                         570       580
                  ....*....|....*....|....*...
gi 119611609  668 LRKSRQHQMQLVDSIVRQRDMYRILLSQ 695
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLE 743
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1057-1694 7.91e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 7.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1057 VTEEVRKNIEvRLKESAE----FQtQLEKKLMEVEKEKQELQDDKRRA-IESMEQQLSELKKTLSSVQNEVQE---ALQR 1128
Cdd:COG1196   194 ILGELERQLE-PLERQAEkaerYR-ELKEELKELEAELLLLKLRELEAeLEELEAELEELEAELEELEAELAEleaELEE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1129 ASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQvskMASVRQHLEETTQKAESQLLECKASWEE 1208
Cdd:COG1196   272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE---LEEELAELEEELEELEEELEELEEELEE 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1209 RERMLKDEVskcvcrcEDLEKQNRLLHDQIEKLSDKVVAsvkegvqgplnvsLSEEGKSQEQILEILRFIRREKEIAETR 1288
Cdd:COG1196   349 AEEELEEAE-------AELAEAEEALLEAEAELAEAEEE-------------LEELAEELLEALRAAAELAAQLEELEEA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1289 FEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTEtmnvvmETNKMLREEKERLEQDLQQM 1368
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL------ELLAELLEEAALLEAALAEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1369 QAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDvKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTE 1448
Cdd:COG1196   483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR-GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1449 EIGRLKAEIA-RSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIG--RRYKTQYEELKA 1525
Cdd:COG1196   562 AIEYLKAAKAgRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLvaARLEAALRRAVT 641

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1526 QQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQ 1605
Cdd:COG1196   642 LAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1606 DLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTK---------------------ENEELKQRNGALD 1664
Cdd:COG1196   722 EEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERelerlereiealgpvnllaieEYEELEERYDFLS 801

                         650       660       670
                  ....*....|....*....|....*....|
gi 119611609 1665 QQKDELDVRITALksqyEGRISRLERELRE 1694
Cdd:COG1196   802 EQREDLEEARETL----EEAIEEIDRETRE 827
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 947-1759 1.86e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 73.23  E-value: 1.86e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   947 QLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLsNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLrqteEQVNDL 1026
Cdd:pfam15921   86 QVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM-QMERDAMADIRRRESQSQEDLRNQLQNTVHEL----EAAKCL 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1027 KE-RLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQT--------QLEKKLMEVEKEKQELQDdk 1097
Cdd:pfam15921  161 KEdMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTmhfrslgsAISKILRELDTEISYLKG-- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1098 rrAIESMEQQLSELKktlSSVQNEVQEALQ----RASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLhaadveALQA 1173
Cdd:pfam15921  239 --RIFPVEDQLEALK---SESQNKIELLLQqhqdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI------IQEQ 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1174 AKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLK-------DEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVV 1246
Cdd:pfam15921  308 ARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1247 ASVKE-GVQGPLNVSLSEEGKSQEQILEILRfirreKEIAETRFEVAQVESL--RYRQRVELLERELQELQDSLNAEREK 1323
Cdd:pfam15921  388 KREKElSLEKEQNKRLWDRDTGNSITIDHLR-----RELDDRNMEVQRLEALlkAMKSECQGQMERQMAAIQGKNESLEK 462

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1324 VQ-VTAKTMAQHEELMKKTETMNvvmeTNKMLREEKERLEQDLQ-QMQAKVRKLEldilplqEANAELSEksgmLQAEKK 1401
Cdd:pfam15921  463 VSsLTAQLESTKEMLRKVVEELT----AKKMTLESSERTVSDLTaSLQEKERAIE-------ATNAEITK----LRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1402 LLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ-----QLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1476
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQienmtQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ 607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1477 DLNKVRTEKETIQKDLDAKIIDIQ-EKVKTITqvkkigrrykTQYEELKAQQDKVMETSaqssgdhqeqhvsvQEMQELK 1555
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLElEKVKLVN----------AGSERLRAVKDIKQERD--------------QLLNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1556 ETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQ-------LRQQITEKeekt 1628
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHamkvamgMQKQITAK---- 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1629 RKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQ-------QKDELDVRITALKSQ---YEGRISRLERELREHQER 1698
Cdd:pfam15921  740 RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQelstvatEKNKMAGELEVLRSQerrLKEKVANMEVALDKASLQ 819

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609  1699 HLEQRDEPQEPSNKVPEQQRQITLKTTPASGErGIASTSDPPTANIKPTPVVSTPSKVTAA 1759
Cdd:pfam15921  820 FAECQDIIQRQEQESVRLKLQHTLDVKELQGP-GYTSNSSMKPRLLQPASFTRTHSNVPSS 879
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1354-1669 2.20e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 2.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1354 LREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSgmLQAEKKLLEEDVKRWKARNQHLvSQQKDPDTEEYRKLL 1433
Cdd:TIGR02168  218 LKAELRELELALLVLRLEELREELEELQEELKEAEEELEE--LTAELQELEEKLEELRLEVSEL-EEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1434 SEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKkig 1513
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE--- 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1514 RRYKTQYEELKAQQDKVMETSaqssgdhqeqhvsvQEMQELKETLNQAETKSKSLESQVENLQKTLSE-----KETEARN 1588
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLE--------------LQIASLNNEIERLEARLERLEDRRERLQQEIEEllkklEEAELKE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1589 LQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEktrkAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKD 1668
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQ----ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK 513


                   .
gi 119611609  1669 E 1669
Cdd:TIGR02168  514 N 514
PTZ00121 PTZ00121
MAEBL; Provisional
 1054-1707 2.71e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 2.71e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1054 EKQVTEEVRKNIEVRLKESAEfQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTAL 1133
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAAR-KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAH 1264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1134 SNEQQARRDCQEQAKI-----AVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAEsqllECKASWEE 1208
Cdd:PTZ00121 1265 FARRQAAIKAEEARKAdelkkAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD----AAKKKAEE 1340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1209 RERmlKDEVSKCvcrcEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETR 1288
Cdd:PTZ00121 1341 AKK--AAEAAKA----EAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAA 1414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1289 FEVAQVESLRYR-QRVELLERELQELQDSLNAEREKVQVTAKTMAqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQ 1367
Cdd:PTZ00121 1415 AAKKKADEAKKKaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA--EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA 1492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1368 MQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRwKARNQHLVSQQKDPD----TEEYRKLLSEKEVHTKRI 1443
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK-KADEAKKAEEKKKADelkkAEELKKAEEKKKAEEAKK 1571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1444 QQLTEEIGRLKAEIARSnaslTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIdiQEKVKTITQVKKIGRRYKTQYEEL 1523
Cdd:PTZ00121 1572 AEEDKNMALRKAEEAKK----AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK--AEELKKAEEEKKKVEQLKKKEAEE 1645

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1524 KAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQvenlqktLSEKETEARNLQEqtvqlqselsrL 1603
Cdd:PTZ00121 1646 KKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA-------LKKEAEEAKKAEE-----------L 1707

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1604 RQDLQDRTTQEEQLRQqitEKEEKTRKAivaakskiahlagvkDQLTKENEELKQRNGALDQQKDELDvRITALKSQYEG 1683
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKK---AEEENKIKA---------------EEAKKEAEEDKKKAEEAKKDEEEKK-KIAHLKKEEEK 1768

                         650       660
                  ....*....|....*....|....
gi 119611609 1684 RISRLERELREHQERHLEQRDEPQ 1707
Cdd:PTZ00121 1769 KAEEIRKEKEAVIEEELDEEDEKR 1792
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 95-582 1.06e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 70.43  E-value: 1.06e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    95 KSVQNKLEKFLADQQSEIDGLKGRHEKFK------VESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKal 168
Cdd:TIGR04523  172 ENELNLLEKEKLNIQKNIDKIKNKLLKLElllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS-- 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   169 tEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQ---ELEYLTED-----VKRLNEKLKESNTTKGELQL 240
Cdd:TIGR04523  250 -NTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQlksEISDLNNQkeqdwNKELKSELKNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   241 KLDELQASDVSVKAK-KRLEQEKELLHSQNTWLNTELKTKTDELLALGREKG----------NEILELKCNLENKKEEVS 309
Cdd:TIGR04523  329 QISQNNKIISQLNEQiSQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQsykqeiknleSQINDLESKIQNQEKLNQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   310 RLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH------NELNAHIK--------LSNLYKSAADDSEAKS 375
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSvkeliiKNLDNTREsletqlkvLSRSINKIKQNLEQKQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   376 NELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSK---DQMEKEMLEK---IGRLEKELENANDLLSATKRKGAILSEEE 449
Cdd:TIGR04523  489 KELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKekiEKLESEKKEKeskISDLEDELNKDDFELKKENLEKEIDEKNK 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   450 laamsptaaavaKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASL 529
Cdd:TIGR04523  569 ------------EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 119611609   530 SVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMEL 582
Cdd:TIGR04523  637 KSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKEL 689
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 234-1124 1.43e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 70.39  E-value: 1.43e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   234 TKGELQLKLDELQA-SDVSVKAKKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE 312
Cdd:pfam02463  150 MKPERRLEIEEEAAgSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   313 EQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEA 392
Cdd:pfam02463  230 DYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   393 GEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVkpgmKLTE 472
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEK-EEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK----LESE 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   473 LYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEakapILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANK 552
Cdd:pfam02463  385 RLSSAAKLKEEELELKSEEEKEAQLLLELARQLE----DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   553 QSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVAL 632
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   633 RELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQrdmYRILLSQTTGVAIPLHASSLDDVS 712
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS---IAVLEIDPILNLAQLDKATLEADE 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   713 LASTPKRPSTSQTVSTpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQ 792
Cdd:pfam02463  618 DDKRAKVVEGILKDTE-------LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   793 LDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEvraENLKKEKEMLKLSEVR 872
Cdd:pfam02463  691 KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   873 LSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTK 952
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   953 RQLDTETNLHLNTKELLKNAQKEIATLKQHLSN-MEVQVASQSSQRTGKGQpsnKEDVDDLVSQLRQTEEQVNDLKERLK 1031
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLLKEEELEeQKLKDELESKEEKEKEE---KKELEEESQKLNLLEEKENEIEERIK 924

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1032 TSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQdDKRRAIESMEQQLSEL 1111
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE-ERYNKDELEKERLEEE 1003

                          890
                   ....*....|...
gi 119611609  1112 KKTLSSVQNEVQE 1124
Cdd:pfam02463 1004 KKKLIRAIIEETC 1016
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 99-687 2.91e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    99 NKLEKFLADQQSEIDglkgRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIA 178
Cdd:TIGR02168  242 EELQEELKEAEEELE----ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   179 QDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAK--- 255
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQias 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   256 -----KRLEQEKELLHSQNTWLNTELKTKTDELLALGREK-GNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHV 329
Cdd:TIGR02168  398 lnneiERLEARLERLEDRRERLQQEIEELLKKLEEAELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   330 EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKS---------NELTRAVEE-----LHKLLKEAGEA 395
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvdEGYEAAIEAalggrLQAVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   396 NKAIQDHLLEVEQSK-----------DQMEKEMLEKIGRLEKELENANDLLSATKRK----GAILSEEELAAMSPTAAAV 460
Cdd:TIGR02168  558 AKKAIAFLKQNELGRvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalSYLLGGVLVVDDLDNALEL 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   461 AKIVKPGMKLTEL-----------YNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASL 529
Cdd:TIGR02168  638 AKKLRPGYRIVTLdgdlvrpggviTGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   530 SVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGnHVIRDEEVSSADISSSSEVIS 609
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKE 796

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   610 QHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSK-----------------------ITELQLKLESALTELE 666
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieelsedieslaaeIEELEELIEELESELE 876

                          650       660
                   ....*....|....*....|.
gi 119611609   667 QLRKSRQHQMQLVDSIVRQRD 687
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELE 897
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1048-1721 3.09e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 3.09e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1048 EESLNKEKQVTEEVRKNIEvrlkeSAEFQTQLEKKLMEVEKEKQELQ-----------DDKRRAIESMEQQLSELKKTLS 1116
Cdd:TIGR02168  185 RENLDRLEDILNELERQLK-----SLERQAEKAERYKELKAELRELElallvlrleelREELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1117 SVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVS-KMASVRQHLEETtQKA 1195
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEaQLEELESKLDEL-AEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1196 ESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVasvkegvqgplnvslseegksqeQILEIL 1275
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-----------------------QLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1276 RFIRREKEIAETRFEVAQVESLRYRQRVELLERelqelqdslNAEREKVQVTAKTMAQHEELMKKTETMNVVMEtnkmlr 1355
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLK---------KLEEAELKELQAELEELEEELEELQEELERLE------ 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1356 eekERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH-----LVSQQKDPDtEEYR 1430
Cdd:TIGR02168  461 ---EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgVLSELISVD-EGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1431 K------------LLSEKEVHTKRIQQLTEEIGRLKAEI--------ARSNASLTNNQNLIQSLKEDLNKVRTEKETIQK 1490
Cdd:TIGR02168  537 AaieaalggrlqaVVVENLNAAKKAIAFLKQNELGRVTFlpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRK 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1491 DLDAkIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKEtlnqAETKSKSLES 1570
Cdd:TIGR02168  617 ALSY-LLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEE----LEEKIEELEE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1571 QVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLT 1650
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609  1651 KENEELKQRNGALDQQKDELDVRITALKSQYEgRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQIT 1721
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALRE-ALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 98-817 8.87e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 8.87e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    98 QNKLEKFLADQQSEIDGLKGRHEKFkvesEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEI 177
Cdd:TIGR02168  276 VSELEEEIEELQKELYALANEISRL----EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   178 AQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQaSDVSVKAKKR 257
Cdd:TIGR02168  352 ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQ-QEIEELLKKL 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   258 LEQEKELLHSQNTWLNTELkTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLK 337
Cdd:TIGR02168  431 EEAELKELQAELEELEEEL-EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   338 EAKEQQasmeekfhNELNAHI-KLSNLYKSAADDSEAKSNELTravEELHKLLKEAGEANKAIQDHLLEVEQSK------ 410
Cdd:TIGR02168  510 ALLKNQ--------SGLSGILgVLSELISVDEGYEAAIEAALG---GRLQAVVVENLNAAKKAIAFLKQNELGRvtflpl 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   411 -----DQMEKEMLEKIGRLEKELENANDLLSATKRK----GAILSEEELAAMSPTAAAVAKIVKPGMKLTEL-------- 473
Cdd:TIGR02168  579 dsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLdgdlvrpg 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   474 ---YNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKA 550
Cdd:TIGR02168  659 gviTGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   551 NKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGnHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLV 630
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   631 ALRELGETREREEQETTSSK--ITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDmyrILLSQTTGVAIPLHASSL 708
Cdd:TIGR02168  818 EAANLRERLESLERRIAATErrLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE---ALLNERASLEEALALLRS 894

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   709 DDVSLASTPKRpstsqtvstpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVtdlrsqntk 788
Cdd:TIGR02168  895 ELEELSEELRE----------------LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY--------- 949

                          730       740
                   ....*....|....*....|....*....
gi 119611609   789 iSTQLDFASKRYEMLQDNVEGYRREITSL 817
Cdd:TIGR02168  950 -SLTLEEAEALENKIEDDEEEARRRLKRL 977
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
99-568 8.93e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 8.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   99 NKLEKFLADQQSEIDGLKGRHEKFK------VESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALtekn 172
Cdd:PRK03918  210 NEISSELPELREELEKLEKEVKELEelkeeiEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL---- 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  173 KELEIAQDRNIAIQsqftRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKG---ELQLKLDELQASD 249
Cdd:PRK03918  286 KELKEKAEEYIKLS----EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKklkELEKRLEELEERH 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  250 VSVKAKKRLEQEKELLHSQNTWLNTE-LKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKT-------- 320
Cdd:PRK03918  362 ELYEEAKAKKEELERLKKRLTGLTPEkLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvc 441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  321 ----SNEHLQ----------KHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSN-------ELT 379
Cdd:PRK03918  442 grelTEEHRKelleeytaelKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKlkkynleELE 521

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  380 RAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK--EMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTA 457
Cdd:PRK03918  522 KKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKlaELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFY 601

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  458 AAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPIL-----KRQREEYERAQKAVASLSVK 532
Cdd:PRK03918  602 NEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLELSRELAGLRAE 681

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 119611609  533 LEQAMKEIQRLQEDTDKANKQssVLERDNRRMEIQV 568
Cdd:PRK03918  682 LEELEKRREEIKKTLEKLKEE--LEEREKAKKELEK 715
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1349-1698 1.04e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 1.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1349 ETNKMLREEKERLEQDLQQMQAKVRK---LELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPD 1425
Cdd:TIGR04523  187 KNIDKIKNKLLKLELLLSNLKKKIQKnksLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIK 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1426 TEEYRKLLsEKEVHTKRIQQLTEEIGRLKAEIarSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKT 1505
Cdd:TIGR04523  267 KQLSEKQK-ELEQNNKKIKELEKQLNQLKSEI--SDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1506 ITQVKKIGRRYKTQYEELKAQQDKvmetsaqssgDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETE 1585
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1586 ARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQ 1665
Cdd:TIGR04523  414 IKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS 493

                          330       340       350
                   ....*....|....*....|....*....|...
gi 119611609  1666 QKDELDvRITALKSQYEGRISRLERELREHQER 1698
Cdd:TIGR04523  494 KEKELK-KLNEEKKELEEKVKDLTKKISSLKEK 525
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 753-1678 1.11e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 67.30  E-value: 1.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   753 IFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFA-SKRYEMLQDNVEGYRREITSLH------ERNQKLT 825
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKkALEYYQLKEKLELEEEYLLYLDylklneERIDLLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   826 ATTQKQEQIINTMTQDLRGANEKLavaEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSE 905
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKL---AQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   906 TEtKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLldtKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSN 985
Cdd:pfam02463  321 KE-KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELE---KLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   986 MEVQvasqssqrtgkgqpSNKEDVDDLVSQLRQTEEqvNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQvteevrkni 1065
Cdd:pfam02463  397 LELK--------------SEEEKEAQLLLELARQLE--DLLKEEKKEELEILEEEEESIELKQGKLTEEKE--------- 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1066 evrlkesaefqTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQE 1145
Cdd:pfam02463  452 -----------ELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1146 QAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMAsVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE 1225
Cdd:pfam02463  521 GGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA-DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1226 DLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVEL 1305
Cdd:pfam02463  600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1306 LERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEA 1385
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1386 NAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIArsnaSLT 1465
Cdd:pfam02463  760 EEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE----EEL 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1466 NNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQH 1545
Cdd:pfam02463  836 EELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEK 915

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1546 VSV--QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQlqselsrlrqdlqdrttqeeqlrqqitE 1623
Cdd:pfam02463  916 ENEieERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL---------------------------A 968

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 119611609  1624 KEEKTRKAIVAAKSKIAhlagvKDQLTKENEELKQRNGALDQQKDELDVRITALK 1678
Cdd:pfam02463  969 KEELGKVNLMAIEEFEE-----KEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1349-1720 1.78e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.58  E-value: 1.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1349 ETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEE 1428
Cdd:TIGR04523  243 EKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1429 YRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNaslTNNQNLIQSLKEDLNKVRTEKETIQ------KDLDAKIIDIQEK 1502
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSE---SENSEKQRELEEKQNEIEKLKKENQsykqeiKNLESQINDLESK 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1503 VKTITQVKKIG----RRYKTQYEELKAQQDKVMET--SAQSSGDHQEQHVSVQEM---------QELKETLNQAETKSKS 1567
Cdd:TIGR04523  400 IQNQEKLNQQKdeqiKKLQQEKELLEKEIERLKETiiKNNSEIKDLTNQDSVKELiiknldntrESLETQLKVLSRSINK 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1568 LESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKS-----KIAHL 1642
Cdd:TIGR04523  480 IKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddfelKKENL 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1643 AGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQ----------YEGRISRLERELREHQERH---LEQRDEPQEP 1709
Cdd:TIGR04523  560 EKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEkkdlikeieeKEKKISSLEKELEKAKKENeklSSIIKNIKSK 639

                          410
                   ....*....|.
gi 119611609  1710 SNKVPEQQRQI 1720
Cdd:TIGR04523  640 KNKLKQEVKQI 650
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
954-1592 2.08e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 66.63  E-value: 2.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  954 QLDTETNLHLNTKELLKNAQKEIATLKQHLS---NMEVQVASQSSQRTGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERL 1030
Cdd:PRK03918  156 GLDDYENAYKNLGEVIKEIKRRIERLEKFIKrteNIEELIKEKEKELEEV-----LREINEISSELPELREELEKLEKEV 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1031 KTstsnVEQYQAMVTSLE---ESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVE--KEKQELQDDKRRAIESME 1105
Cdd:PRK03918  231 KE----LEELKEEIEELEkelESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYL 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1106 QQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIaveaqnkyERELMLHAADVEALQAAKEQVSKMASVR 1185
Cdd:PRK03918  307 DELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKEL--------EKRLEELEERHELYEEAKAKKEELERLK 378

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1186 QHLE-ETTQKAESQLLECkaswEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKvvasvkEGVQGPLNVSLSEE 1264
Cdd:PRK03918  379 KRLTgLTPEKLEKELEEL----EKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA------KGKCPVCGRELTEE 448

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1265 GKsqeqiLEILRFIRRE-KEIAETRFEVAQVESlryrqrvellerelqelqdslNAEREKVQVtaktmaqhEELMKKTET 1343
Cdd:PRK03918  449 HR-----KELLEEYTAElKRIEKELKEIEEKER---------------------KLRKELREL--------EKVLKKESE 494

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1344 MNVVMETNKMLREEKERLEQ-DLQQMQAKVRKLEldilplqeanaELSEKSGMLQAEKKLLEEDVKRWKARNQHL--VSQ 1420
Cdd:PRK03918  495 LIKLKELAEQLKELEEKLKKyNLEELEKKAEEYE-----------KLKEKLIKLKGEIKSLKKELEKLEELKKKLaeLEK 563

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1421 QKDPDTEEYRKLLSE-KEVHTKRIQQLTEEIGRLKaEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDI 1499
Cdd:PRK03918  564 KLDELEEELAELLKElEELGFESVEELEERLKELE-PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRL 642

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1500 QEKVKTITQVKKIgrryktqyeelkaqqdkvmetsaqssgdhqeqhVSVQEMQELKETLNQAETKSKSLESQVENLQKTL 1579
Cdd:PRK03918  643 EELRKELEELEKK---------------------------------YSEEEYEELREEYLELSRELAGLRAELEELEKRR 689

                         650
                  ....*....|...
gi 119611609 1580 SEKETEARNLQEQ 1592
Cdd:PRK03918  690 EEIKKTLEKLKEE 702
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 964-1704 2.96e-10

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 66.22  E-value: 2.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   964 NTKELLKNAQKEIATLKQHLSNMEVQVASQSSqRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAM 1043
Cdd:TIGR00606  245 NELDPLKNRLKEIEHNLSKIMKLDNEIKALKS-RKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVD 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1044 VTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---------------DKRRAIESMEQQL 1108
Cdd:TIGR00606  324 CQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATrleldgfergpfserQIKNFHTLVIERQ 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1109 SELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKM-ASVRQH 1187
Cdd:TIGR00606  404 EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELdQELRKA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1188 LEETTQKAESQLLECKASWEERERMLKDEVSKCVCR-CEDLEKQNRLLHDQIEKLS------DKVVASVKEGVQGPLN-V 1259
Cdd:TIGR00606  484 ERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKlDQEMEQLNHHTTTRTQMEMltkdkmDKDEQIRKIKSRHSDElT 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1260 SLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMK 1339
Cdd:TIGR00606  564 SLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLER 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1340 ktetmnvvmetnkmLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVS 1419
Cdd:TIGR00606  644 --------------LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPD 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1420 QQKDPDTEeYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIiDI 1499
Cdd:TIGR00606  710 KLKSTESE-LKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAK-VC 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1500 QEKVKTITQVkkigrryktqYEELKAQQDKVMETSAQSSGDHQEQHVsvqemQELKETLNQAETKSKSLESQVENLQKTL 1579
Cdd:TIGR00606  788 LTDVTIMERF----------QMELKDVERKIAQQAAKLQGSDLDRTV-----QQVNQEKQEKQHELDTVVSKIELNRKLI 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1580 SEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRkAIVAAKSKIAHLAGVKDQLTKENEELKQR 1659
Cdd:TIGR00606  853 QDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIR-EIKDAKEQDSPLETFLEKDQQEKEELISS 931

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 119611609  1660 NGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRD 1704
Cdd:TIGR00606  932 KETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKE 976
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 130-1197 4.51e-10

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 65.84  E-value: 4.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   130 YFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEK-----NKELEIaQDRNIAIQSQFTRTKEELE--AEKRD 202
Cdd:TIGR01612  539 YKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEikdlfDKYLEI-DDEIIYINKLKLELKEKIKniSDKNE 617

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   203 LIRTNERLSQELE----YLTEDVK----RLNEKLKESNTTKGELQLKLDELQASDVSvkakkRLEQEKELLHSQNTWLNT 274
Cdd:TIGR01612  618 YIKKAIDLKKIIEnnnaYIDELAKispyQVPEHLKNKDKIYSTIKSELSKIYEDDID-----ALYNELSSIVKENAIDNT 692

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   275 ELKTKTDELLALGREKGNEILELK--------CNLENKKEEVSRLEEQMNGLKTS--NEHLQKHVEDLLTKLKE------ 338
Cdd:TIGR01612  693 EDKAKLDDLKSKIDKEYDKIQNMEtatvelhlSNIENKKNELLDIIVEIKKHIHGeiNKDLNKILEDFKNKEKElsnkin 772

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   339 --AKEQQ-----ASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAV----EELHKLLKEAgeanKAIQDHLLEVE 407
Cdd:TIGR01612  773 dyAKEKDelnkyKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTIsikeDEIFKIINEM----KFMKDDFLNKV 848

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   408 QSKDQMEKEMLEKIgrlEKELENANDLLSATKRKgaiLSEEELA----AMSPTAAAVAKIVKPGMKLTELYNAYVETQDQ 483
Cdd:TIGR01612  849 DKFINFENNCKEKI---DSEHEQFAELTNKIKAE---ISDDKLNdyekKFNDSKSLINEINKSIEEEYQNINTLKKVDEY 922

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   484 L--------LLEKLENKR--INKYLDEIVKEVEAKAPILKRQREEYERA--------QKAVASLSV-----KLEQAMKEI 540
Cdd:TIGR01612  923 IkicentkeSIEKFHNKQniLKEILNKNIDTIKESNLIEKSYKDKFDNTlidkinelDKAFKDASLndyeaKNNELIKYF 1002

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   541 QRLQED--TDKAN---KQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNhvIRDE---EVSSADISSSSEVISQHL 612
Cdd:TIGR01612 1003 NDLKANlgKNKENmlyHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYN--IIDEiekEIGKNIELLNKEILEEAE 1080

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   613 VSYRNIEELQQQNQRL-LVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHqmqLVDSIVRQrdmyri 691
Cdd:TIGR01612 1081 INITNFNEIKEKLKHYnFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSEN---YIDEIKAQ------ 1151

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   692 llsqttgvaiplhASSLDDVslastpkrpsTSQTVSTPAPVPVIESTEAIEAKAALKqlQEIFENYKKEKAENEKIQNEQ 771
Cdd:TIGR01612 1152 -------------INDLEDV----------ADKAISNDDPEEIEKKIENIVTKIDKK--KNIYDEIKKLLNEIAEIEKDK 1206

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   772 --LEKLQE-QVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQK------LTATTQKQEQIINTMTQDL 842
Cdd:TIGR01612 1207 tsLEEVKGiNLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEienemgIEMDIKAEMETFNISHDDD 1286

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   843 R-----GANEKLAVAEVRAENLKKEK---EMLKLSEVRLSQQRESLLAEQRGQ--NLLLTNLQTIQGILERSETetkQRL 912
Cdd:TIGR01612 1287 KdhhiiSKKHDENISDIREKSLKIIEdfsEESDINDIKKELQKNLLDAQKHNSdiNLYLNEIANIYNILKLNKI---KKI 1363

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   913 SSQIEKLEHEISHLKKKLENEVEQRHTLTRNL--DVQLLDTKRQLD---------------TETNLHL-----NTKELLK 970
Cdd:TIGR01612 1364 IDEVKEYTKEIEENNKNIKDELDKSEKLIKKIkdDINLEECKSKIEstlddkdidecikkiKELKNHIlseesNIDTYFK 1443

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   971 NAQKEIATLKQHLSNMEvqVASQSSQRTGKGQPSN-KEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVE-------QYQA 1042
Cdd:TIGR01612 1444 NADENNENVLLLFKNIE--MADNKSQHILKIKKDNaTNDHDFNINELKEHIDKSKGCKDEADKNAKAIEknkelfeQYKK 1521

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1043 MVTSLeesLNKEKQVT-----EEVRKNIEVRLKESAEFQTQL-------EKKLMEVEKEKQELQDDKRRAIESmeqqlse 1110
Cdd:TIGR01612 1522 DVTEL---LNKYSALAiknkfAKTKKDSEIIIKEIKDAHKKFileaeksEQKIKEIKKEKFRIEDDAAKNDKS------- 1591

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1111 lKKTLSSVQNEVqEALQRASTALSNEQQARRDCQEQA-----KIAVEAQNKYERELMLHAADVEALQ----AAKEQVSKM 1181
Cdd:TIGR01612 1592 -NKAAIDIQLSL-ENFENKFLKISDIKKKINDCLKETesiekKISSFSIDSQDTELKENGDNLNSLQefleSLKDQKKNI 1669

                         1210
                   ....*....|....*.
gi 119611609  1182 ASVRQHLEETTQKAES 1197
Cdd:TIGR01612 1670 EDKKKELDELDSEIEK 1685
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 755-1511 5.27e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 65.04  E-value: 5.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   755 ENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQI 834
Cdd:TIGR04523   60 DKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKN 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   835 INTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQrLSS 914
Cdd:TIGR04523  140 IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKS-LES 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   915 QIEKLEHEishlKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQS 994
Cdd:TIGR04523  219 QISELKKQ----NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   995 SQrtgkgqpsnkedvddlVSQLRQTEEQV--NDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKES 1072
Cdd:TIGR04523  295 SE----------------ISDLNNQKEQDwnKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESEN 358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1073 AEFQTQLEKKLMEVEKEKQElQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDcQEQAKIAVE 1152
Cdd:TIGR04523  359 SEKQRELEEKQNEIEKLKKE-NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE-IERLKETII 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1153 AQNKYERELmlhaadVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCvcrcEDLEKQNR 1232
Cdd:TIGR04523  437 KNNSEIKDL------TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL----KKLNEEKK 506

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1233 LLHDQIEKLSDKVvasvkegvqgplnvslsEEGKSQEQILEilrfirreKEIAETRFEVAQVESlryrqrvellerelqe 1312
Cdd:TIGR04523  507 ELEEKVKDLTKKI-----------------SSLKEKIEKLE--------SEKKEKESKISDLED---------------- 545

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1313 lqdslnaerekvqvtaktmaqheELMKKTETMNvvmetnkmlreeKERLEQDLQQMQAKVRKLELDILPLQEANAELSEK 1392
Cdd:TIGR04523  546 -----------------------ELNKDDFELK------------KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQEL 590

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1393 SGMLQAEKKlleedvkrwkarnqhlvsqqkdpdteeyrKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQ 1472
Cdd:TIGR04523  591 IDQKEKEKK-----------------------------DLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 119611609  1473 SLKEDLNKVRTE-KETIQK--DLDAKIIDIQEKVKTITQVKK 1511
Cdd:TIGR04523  642 KLKQEVKQIKETiKEIRNKwpEIIKKIKESKTKIDDIIELMK 683
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1193-1713 7.74e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 7.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1193 QKAESQLLECKASWEERERMLKDEVSkcvcRCEDLEKQNRLLHDQIEKLSDKVvasvkegvqgplNVSLSEEGKSQEQIL 1272
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIK----RTENIEELIKEKEKELEEVLREI------------NEISSELPELREELE 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1273 EILRFIRREKEIAEtRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNK 1352
Cdd:PRK03918  225 KLEKEVKELEELKE-EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYE 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1353 MLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE---------EDVKRWKARNQHLVSQQKD 1423
Cdd:PRK03918  304 EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEeleerhelyEEAKAKKEELERLKKRLTG 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1424 PDTEEYRKLLSE----KEVHTKRIQQLTEEIGRLKAEIARSNASLT-------------------NNQNLIQSLKEDLNK 1480
Cdd:PRK03918  384 LTPEKLEKELEElekaKEEIEEEISKITARIGELKKEIKELKKAIEelkkakgkcpvcgrelteeHRKELLEEYTAELKR 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1481 VRTEKETIqKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVmetsaqSSGDHQEQHVSVQEMQELKETLNQ 1560
Cdd:PRK03918  464 IEKELKEI-EEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKL------KKYNLEELEKKAEEYEKLKEKLIK 536

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1561 AETKSKSLESQVENLQKTLSEKETEARNLQEqtvqLQSELSRLRQDLQDRT-TQEEQLRQQITEKEEKTRKAIvaakski 1639
Cdd:PRK03918  537 LKGEIKSLKKELEKLEELKKKLAELEKKLDE----LEEELAELLKELEELGfESVEELEERLKELEPFYNEYL------- 605

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119611609 1640 aHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSqYEGRISRLERELREhqERHLEQRDEPQEPSNKV 1713
Cdd:PRK03918  606 -ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE-LRKELEELEKKYSE--EEYEELREEYLELSREL 675
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1354-1526 8.38e-10

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 61.48  E-value: 8.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1354 LREEKERLEQDLQQMQAKVRKLELDilpLQEANAELSEksgmLQAEKKLLEEDVKRWKARNQHLVSQQKD-PDTEEYRKL 1432
Cdd:COG1579    22 LEHRLKELPAELAELEDELAALEAR---LEAAKTELED----LEKEIKRLELEIEEVEARIKKYEEQLGNvRNNKEYEAL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1433 LSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTItqVKKI 1512
Cdd:COG1579    95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL--AAKI 172

                         170
                  ....*....|....
gi 119611609 1513 GRRYKTQYEELKAQ 1526
Cdd:COG1579   173 PPELLALYERIRKR 186
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 199-1128 8.85e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 8.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   199 EKRDLIrtnERLSQELEYLTEDVKRLNEkLKESNTTKGELQLKLDELQasdvsvKAKKRLEQEKELLHSQNtwlntELKT 278
Cdd:TIGR02169  154 ERRKII---DEIAGVAEFDRKKEKALEE-LEEVEENIERLDLIIDEKR------QQLERLRREREKAERYQ-----ALLK 218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   279 KTDELLalGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHI 358
Cdd:TIGR02169  219 EKREYE--GYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKI 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   359 -KLSNLYKSAADDSEAKSNELTRAVEELHKLLKEageankaIQDHLLEVEQSKDQMEKEMLEKIgRLEKELENANDLLSA 437
Cdd:TIGR02169  297 gELEAEIASLERSIAEKERELEDAEERLAKLEAE-------IDKLLAEIEELEREIEEERKRRD-KLTEEYAELKEELED 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   438 TKRKgailSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKlenkrinKYLDEIVKEVEAKAPILKRQRE 517
Cdd:TIGR02169  369 LRAE----LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL-------QRLSEELADLNAAIAGIEAKIN 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   518 EYERAQKAVASlsvKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIrvllmeleeargnhvirdEEVS 597
Cdd:TIGR02169  438 ELEEEKEDKAL---EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL------------------AEAE 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   598 SADISSSSEVISqhlvSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQ-------LKLESALTELEQLRK 670
Cdd:TIGR02169  497 AQARASEERVRG----GRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvveddAVAKEAIELLKRRKA 572

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   671 SRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLhasslddvsLASTPK-RPSTSQTVSTPAPVPVIESTEAIEAKAALKQ 749
Cdd:TIGR02169  573 GRATFLPLNKMRDERRDLSILSEDGVIGFAVDL---------VEFDPKyEPAFKYVFGDTLVVEDIEAARRLMGKYRMVT 643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   750 LQ-EIFE-----------------NYKKEKAENEKIQnEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYR 811
Cdd:TIGR02169  644 LEgELFEksgamtggsraprggilFSRSEPAELQRLR-ERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   812 REITSLHERNQKLtattqkQEQIINTMTqDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQnlll 891
Cdd:TIGR02169  723 KEIEQLEQEEEKL------KERLEELEE-DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS---- 791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   892 tNLQTIQGILERSEtETKQRLSSQIEKLEHEIshlkKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEtnlhlntKELLKN 971
Cdd:TIGR02169  792 -RIPEIQAELSKLE-EEVSRIEARLREIEQKL----NRLTLEKEYLEKEIQELQEQRIDLKEQIKSI-------EKEIEN 858

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   972 AQKEIATLKQHLSNMEVQVASQSSQRTGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESL 1051
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDL-----KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1052 nkeKQVTEEVRKNIEVRLKESAEfqTQLEKKLMEVEKEKQELQDDKRRAI---ESMEQQLSELKKTLSSVQNEVQEALQR 1128
Cdd:TIGR02169  934 ---SEIEDPKGEDEEIPEEELSL--EDVQAELQRVEEEIRALEPVNMLAIqeyEEVLKRLDELKEKRAKLEEERKAILER 1008
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 947-1631 2.44e-09

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 63.06  E-value: 2.44e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   947 QLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKE--DVDDLVSQLRQTEEQVN 1024
Cdd:TIGR00618  167 ELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKElkHLREALQQTQQSHAYLT 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1025 DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVtEEVRKNIE-----VRLKESAEFQTQLEKKLMEVEKEKQELQDD--- 1096
Cdd:TIGR00618  247 QKREAQEEQLKKQQLLKQLRARIEELRAQEAVL-EETQERINrarkaAPLAAHIKAVTQIEQQAQRIHTELQSKMRSrak 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1097 ---KRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQA 1173
Cdd:TIGR00618  326 llmKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1174 AKEQVSKMAsvrQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEK--QNRL---LHDQIEKLSDKVVAS 1248
Cdd:TIGR00618  406 QREQATIDT---RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKihLQESaqsLKEREQQLQTKEQIH 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1249 VKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQV-T 1327
Cdd:TIGR00618  483 LQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASlK 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1328 AKTMAQHEELMKKTETMNVVMETNKMLREEKERLeQDLQQMQAKVRKLELDILPLQEANAELS-EKSGMLQAEKKLLEED 1406
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRL-QDLTEKLSEAEDMLACEQHALLRKLQPEqDLQDVRLHLQQCSQEL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1407 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKE 1486
Cdd:TIGR00618  642 ALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFN 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1487 TIQKDLDAKIIDIQEKVKTITQV-KKIGRRYKTQYEELK-AQQDKVMETSAQSSGDHQEQHVS----------VQEMQEL 1554
Cdd:TIGR00618  722 EIENASSSLGSDLAAREDALNQSlKELMHQARTVLKARTeAHFNNNEEVTAALQTGAELSHLAaeiqffnrlrEEDTHLL 801

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609  1555 KETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKA 1631
Cdd:TIGR00618  802 KTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 498-1245 3.23e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.83  E-value: 3.23e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   498 LDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSsvlerdnRRMEIQVKDLSQQIRV 577
Cdd:pfam15921  119 LQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQL-------RKMMLSHEGVLQEIRS 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   578 LLMELEEARGNHVIRDEEVSSADISSSSEVISQhlvsyrnieelqqqnqrllvALRELgetrereeqettSSKITELQLK 657
Cdd:pfam15921  192 ILVDFEEASGKKIYEHDSMSTMHFRSLGSAISK--------------------ILREL------------DTEISYLKGR 239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   658 LESALTELEQLRKSRQHQMQLVdsIVRQRDMYRILLSQttgvaiplHASSLDDVSLASTPKRpstSQTVSTPAPVPVIES 737
Cdd:pfam15921  240 IFPVEDQLEALKSESQNKIELL--LQQHQDRIEQLISE--------HEVEITGLTEKASSAR---SQANSIQSQLEIIQE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   738 TEAIEAKAALKQLQEI---FENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEgyrREI 814
Cdd:pfam15921  307 QARNQNSMYMRQLSDLestVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ---KLL 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   815 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNL 894
Cdd:pfam15921  384 ADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKV 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   895 QTIQGILErsetETKQRLSSQIEKL----------EHEISHLKKKLENevEQRHTLTRNLDVQLLDTKRQLDTETNLHL- 963
Cdd:pfam15921  464 SSLTAQLE----STKEMLRKVVEELtakkmtlessERTVSDLTASLQE--KERAIEATNAEITKLRSRVDLKLQELQHLk 537

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   964 NTKELLKNAQKEIATLKQHLSNME--VQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLK-------TST 1034
Cdd:pfam15921  538 NEGDHLRNVQTECEALKLQMAEKDkvIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQefkilkdKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1035 SNVEQYQAMVTSLEesLNKEKQVTEEVRknievRLKESAEFQTQLEKKLMEVEKEKQELQD----------DKRRAIESM 1104
Cdd:pfam15921  618 AKIRELEARVSDLE--LEKVKLVNAGSE-----RLRAVKDIKQERDQLLNEVKTSRNELNSlsedyevlkrNFRNKSEEM 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1105 EQQLSELKKTLSSVQNEVQEALQRASTALSNEQQArrdcqeqAKIAVEAQNKyerelmlhaadveaLQAAKEQVSKMASV 1184
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHA-------MKVAMGMQKQ--------------ITAKRGQIDALQSK 749

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609  1185 RQHLEETTQKAESQllecKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKV 1245
Cdd:pfam15921  750 IQFLEEAMTNANKE----KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKV 806
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 650-1588 7.93e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   650 KITELQLKLESALTELEQLRKSRQHQMQlvdsivrqrdmYRILLSQTTGVAIPLHASSLddvslastpkrpstsqtvstp 729
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAER-----------YQALLKEKREYEGYELLKEK--------------------- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   730 apvpviesteaieaKAALKQLQEIfenyKKEKAENEkiqnEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNveg 809
Cdd:TIGR02169  233 --------------EALERQKEAI----ERQLASLE----EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE--- 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   810 yrrEITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAE----QR 885
Cdd:TIGR02169  288 ---EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEyaelKE 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   886 GQNLLLTNLQTIQGILERSETETKQRlSSQIEKLEHEISHLKKKLENEVEqrhtLTRNLDVQLLDTKRQLDTETNLHLNT 965
Cdd:TIGR02169  365 ELEDLRAELEEVDKEFAETRDELKDY-REKLEKLKREINELKRELDRLQE----ELQRLSEELADLNAAIAGIEAKINEL 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   966 KELLKNAQKEIATLKQHLSnmevqvasqssqrtgkgqpSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVT 1045
Cdd:TIGR02169  440 EEEKEDKALEIKKQEWKLE-------------------QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1046 SLEESLNKEKQVTEEVRKNIE---------VRLKEsaEFQTQLEK------KLMEVEKEkqelqDDKRRAIESMEqqlse 1110
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQgvhgtvaqlGSVGE--RYATAIEVaagnrlNNVVVEDD-----AVAKEAIELLK----- 568

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1111 lkktlssvqnevQEALQRAS-TALSNEQQARRD--------CQEQAKIAVEAQNKYERELMLHAAD---VEALQAAKEQV 1178
Cdd:TIGR02169  569 ------------RRKAGRATfLPLNKMRDERRDlsilsedgVIGFAVDLVEFDPKYEPAFKYVFGDtlvVEDIEAARRLM 636

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1179 SK--MASVRQHLEETT------QKAESQLLECKASWEERERMLKDEVskcvcrcEDLEKQ-NRLLHDQ--IEKLSDKVVA 1247
Cdd:TIGR02169  637 GKyrMVTLEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERL-------EGLKRElSSLQSELrrIENRLDELSQ 709

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1248 SVKEGVQgplnvSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQvT 1327
Cdd:TIGR02169  710 ELSDASR-----KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALN-D 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1328 AKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDV 1407
Cdd:TIGR02169  784 LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK 863

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1408 krwkarnqhlvsqqkdpdteeyRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKvrteKET 1487
Cdd:TIGR02169  864 ----------------------EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK----KRK 917

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1488 IQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQ---YEELKAQQDKvMETSAQSSGDhqEQHVSVQEMQELKETLNQAETK 1564
Cdd:TIGR02169  918 RLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsLEDVQAELQR-VEEEIRALEP--VNMLAIQEYEEVLKRLDELKEK 994

                          970       980
                   ....*....|....*....|....
gi 119611609  1565 SKSLESQVENLQKTLSEKETEARN 1588
Cdd:TIGR02169  995 RAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1443-1721 1.17e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 1.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1443 IQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQK--DLDAKIIDIQ------EKVKTITQVKKIGR 1514
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYEgyellkEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1515 RYKTQYEEL---KAQQDKVMETSAQSSGDHQEQHVSVQEMQElkETLNQAETKSKSLESQVENLQKTLSEKETEARNLQE 1591
Cdd:TIGR02169  245 QLASLEEELeklTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1592 QTVQLQSELSRLRQDLqdrttqeEQLRQQITEKeektrkaivaakskiahlAGVKDQLTKENEELKQRNGALDQQKDELD 1671
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEI-------EELEREIEEE------------------RKRRDKLTEEYAELKEELEDLRAELEEVD 377

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 119611609  1672 VRITALK---SQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQIT 1721
Cdd:TIGR02169  378 KEFAETRdelKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA 430
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1067-1703 1.23e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.75  E-value: 1.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1067 VRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTAlsneQQARRDCQE- 1145
Cdd:TIGR00618  197 ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLL----KQLRARIEEl 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1146 QAKIAVEAQNKYERELMLHAADVEALQAAKEQVskmasvRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRce 1225
Cdd:TIGR00618  273 RAQEAVLEETQERINRARKAAPLAAHIKAVTQI------EQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQR-- 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1226 DLEKQNRLLHDQIEKLSDKVVASVKEGVQgplNVSLSEEGKSQEQILEILRFIRR--EKEIAETRFEVAQVESLRYRQRV 1303
Cdd:TIGR00618  345 RLLQTLHSQEIHIRDAHEVATSIREISCQ---QHTLTQHIHTLQQQKTTLTQKLQslCKELDILQREQATIDTRTSAFRD 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1304 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTEtmnvVMETNKMLREEKERLE--QDLQQMQAKVRKLELDILP 1381
Cdd:TIGR00618  422 LQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH----LQESAQSLKEREQQLQtkEQIHLQETRKKAVVLARLL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1382 LQEANAELSEKSgmlqaekkLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSN 1461
Cdd:TIGR00618  498 ELQEEPCPLCGS--------CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQ 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1462 ASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKI---------IDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVME 1532
Cdd:TIGR00618  570 QSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSeaedmlaceQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALH 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1533 TSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENL----------QKTLSEKETEARNLQEQTVQLQSELSR 1602
Cdd:TIGR00618  650 ALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLtywkemlaqcQTLLRELETHIEEYDREFNEIENASSS 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1603 LRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYE 1682
Cdd:TIGR00618  730 LGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIG 809

                          650       660
                   ....*....|....*....|.
gi 119611609  1683 GRISRLERELREHQERHLEQR 1703
Cdd:TIGR00618  810 QEIPSDEDILNLQCETLVQEE 830
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 742-1121 1.33e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.42  E-value: 1.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   742 EAKAALKQLQEIFENYKKEKAENEKI---QNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLH 818
Cdd:TIGR04523  311 ELKSELKNQEKKLEEIQNQISQNNKIisqLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   819 ERNQKLTATTQKQEQIintmtqdlrgaNEKLavaEVRAENLKKEKEMLklsevrlsqqresllaEQRGQNLLLTNLQtiq 898
Cdd:TIGR04523  391 SQINDLESKIQNQEKL-----------NQQK---DEQIKKLQQEKELL----------------EKEIERLKETIIK--- 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   899 gilersetetkqrLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRqldTETNLHLNTKElLKNAQKEIAT 978
Cdd:TIGR04523  438 -------------NNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK---IKQNLEQKQKE-LKSKEKELKK 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   979 LKQHLSNMEVQVASQSSQrtgkgQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQamvtsLEESLNKEKQVT 1058
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKK-----ISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEN-----LEKEIDEKNKEI 570

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119611609  1059 EEVRKNIEVRLKEsaefQTQLEKKLMEVEKEKQELqddkRRAIESMEQQLSELKKTLSSVQNE 1121
Cdd:TIGR04523  571 EELKQTQKSLKKK----QEEKQELIDQKEKEKKDL----IKEIEEKEKKISSLEKELEKAKKE 625
PTZ00121 PTZ00121
MAEBL; Provisional
 134-687 1.55e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 1.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  134 EKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIA----QDRNIAIQSQFTRTKEELEAEKRDLIRTNER 209
Cdd:PTZ00121 1198 DARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaeEERNNEEIRKFEEARMAHFARRQAAIKAEEA 1277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  210 LSqeleylTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKKRLEQEKEllhsqntwlntELKTKTDELLALGRE 289
Cdd:PTZ00121 1278 RK------ADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAE-----------EAKKKADAAKKKAEE 1340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  290 KGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNA-HIKLSNLYKSAA 368
Cdd:PTZ00121 1341 AKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKAdELKKAAAAKKKA 1420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  369 DDSEAKSNELTRAvEELHKLLKE---AGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAIL 445
Cdd:PTZ00121 1421 DEAKKKAEEKKKA-DEAKKKAEEakkADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  446 SEEELAAMSPTAAAVAKIVKPGMKLTELYNAYvETQDQLLLEKLENKRinkYLDEIVKEVEAKAPILKRQREEYERAQKA 525
Cdd:PTZ00121 1500 DEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEEKK---KADELKKAEELKKAEEKKKAEEAKKAEED 1575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  526 VASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSS 605
Cdd:PTZ00121 1576 KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA 1655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  606 EviSQHLVSYRNIEELQQQNQRLLVALR-----ELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVD 680
Cdd:PTZ00121 1656 E--EENKIKAAEEAKKAEEDKKKAEEAKkaeedEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAE 1733


                  ....*..
gi 119611609  681 SIVRQRD 687
Cdd:PTZ00121 1734 EAKKEAE 1740
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1434-1640 1.89e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 59.07  E-value: 1.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1434 SEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEkvktitQVKKIG 1513
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE------RREELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1514 RRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSV--------QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETE 1585
Cdd:COG3883    90 ERARALYRSGGSVSYLDVLLGSESFSDFLDRLSALskiadadaDLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 119611609 1586 ARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIA 1640
Cdd:COG3883   170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1486-1736 2.19e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1486 ETIQKDLDaKIIDIQEKVKTitQVKKIGRRYKtQYEELKAQQDKVMETSAQSSGDHQEQHVsvQEMQELKETLNQAETKS 1565
Cdd:TIGR02168  182 ERTRENLD-RLEDILNELER--QLKSLERQAE-KAERYKELKAELRELELALLVLRLEELR--EELEELQEELKEAEEEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1566 KSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITE-----------------KEEKT 1628
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANlerqleeleaqleelesKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1629 RKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQY----------EGRISRLERELrEHQER 1698
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVaqlelqiaslNNEIERLEARL-ERLED 414

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 119611609  1699 HLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIAST 1736
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL 452
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1419-1638 2.92e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 2.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1419 SQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIID 1498
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1499 IQEKVKTI-TQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQK 1577
Cdd:COG4942    99 LEAQKEELaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 119611609 1578 TLSEKETEARNLQEQTVQ-------LQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSK 1638
Cdd:COG4942   179 LLAELEEERAALEALKAErqkllarLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
mukB PRK04863
chromosome partition protein MukB;
1069-1708 3.27e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 59.59  E-value: 3.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1069 LKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIE------SMEQQLSELKKTLSSVQNEV--QEALQRASTALsNEQQAR 1140
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAElneaesDLEQDYQAASDHLNLVQTALrqQEKIERYQADL-EELEER 363

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1141 rdcQEQAKIAVEAQNkyERELMLHAADVEALQAAKEQVSKMASVRQHLEETtQKAESQLLECKASWEErermlkdevSKC 1220
Cdd:PRK04863  364 ---LEEQNEVVEEAD--EQQEENEARAEAAEEEVDELKSQLADYQQALDVQ-QTRAIQYQQAVQALER---------AKQ 428

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1221 VCRCEDLEKQNrlLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQ-EQILEILR--------------FIRREKEIA 1285
Cdd:PRK04863  429 LCGLPDLTADN--AEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQfEQAYQLVRkiagevsrseawdvARELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1286 ETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKV---QVTAKTMAQ--HEELMKKTETMNVVMETnkmLREEKER 1360
Cdd:PRK04863  507 EQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRlgkNLDDEDELEqlQEELEARLESLSESVSE---ARERRMA 583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1361 LEQDLQQMQAKVRKLE---LDILPLQEANAELSEKSG--------MLQAEKKLLEEDVKRWKARNQhlVSQQKDPDTEEY 1429
Cdd:PRK04863  584 LRQQLEQLQARIQRLAaraPAWLAAQDALARLREQSGeefedsqdVTEYMQQLLERERELTVERDE--LAARKQALDEEI 661

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1430 RKLLSEKEVHTKRIQQLTEEI-GRLKAEI------------------ARsNASLTNNQNLIQS-------LKEDLNKV-- 1481
Cdd:PRK04863  662 ERLSQPGGSEDPRLNALAERFgGVLLSEIyddvsledapyfsalygpAR-HAIVVPDLSDAAEqlagledCPEDLYLIeg 740

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1482 --------RTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQY-EELKAQQDKVMETSAQSSGDhqeqhvsVQEMQ 1552
Cdd:PRK04863  741 dpdsfddsVFSVEELEKAVVVKIADRQWRYSRFPEVPLFGRAAREKRiEQLRAEREELAERYATLSFD-------VQKLQ 813

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1553 ELKETLNQAETKSKSL------ESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ-------------DRTTQ 1613
Cdd:PRK04863  814 RLHQAFSRFIGSHLAVafeadpEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSalnrllprlnllaDETLA 893

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1614 E--EQLRQQITEKEEKTR--KAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKS--------QY 1681
Cdd:PRK04863  894 DrvEEIREQLDEAEEAKRfvQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEvvqrrahfSY 973

                         730       740       750
                  ....*....|....*....|....*....|...
gi 119611609 1682 EGRISRLERE------LREHQERHLEQRDEPQE 1708
Cdd:PRK04863  974 EDAAEMLAKNsdlnekLRQRLEQAEQERTRARE 1006
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 618-1194 3.49e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 3.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  618 IEELQQQNQRLLVALREL--GETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQ 695
Cdd:COG1196   248 LEELEAELEELEAELAELeaELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  696 TTGVAIplhasslddvslastpkrpstsqtvstpapvpvIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKL 775
Cdd:COG1196   328 LEEELE---------------------------------ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  776 QEQVTDLRSQNtkiSTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRganEKLAVAEVR 855
Cdd:COG1196   375 AEAEEELEELA---EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE---EEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  856 AENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQtiqgilERSETETKQRLSSQIEKLEHEISHLKKKLENEVE 935
Cdd:COG1196   449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  936 QRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQ 1015
Cdd:COG1196   523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1016 LRQTEEQVNDLKERLktstsnVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD 1095
Cdd:COG1196   603 LVASDLREADARYYV------LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1096 DKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAK 1175
Cdd:COG1196   677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                         570
                  ....*....|....*....
gi 119611609 1176 EQVSKMASVRQHLEETTQK 1194
Cdd:COG1196   757 PEPPDLEELERELERLERE 775
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
746-1295 3.90e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.92  E-value: 3.90e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  746 ALKQLQEIFENYKKEKAENEKIQnEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 825
Cdd:PRK03918  163 AYKNLGEVIKEIKRRIERLEKFI-KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  826 AT---TQKQEQIINTMTQDLRGANEKLAVAEVRAENL-KKEKEMLKLSE-----VRLSQQRESLLAEQRGQNLLLTNL-Q 895
Cdd:PRK03918  242 ELekeLESLEGSKRKLEEKIRELEERIEELKKEIEELeEKVKELKELKEkaeeyIKLSEFYEEYLDELREIEKRLSRLeE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  896 TIQGILER-SETETKqrlSSQIEKLEHEISHLKKKLEnEVEQRHTLTRNLDvQLLDTKRQLDTEtnLHLNTKELLKNAQK 974
Cdd:PRK03918  322 EINGIEERiKELEEK---EERLEELKKKLKELEKRLE-ELEERHELYEEAK-AKKEELERLKKR--LTGLTPEKLEKELE 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  975 EIATLKQHLSNMEVQVASQSSQRTGKGQpSNKEDVDDLVSQLRQ--------TEEQVNDLKERLKTSTSNVEQYQAMVTS 1046
Cdd:PRK03918  395 ELEKAKEEIEEEISKITARIGELKKEIK-ELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEE 473

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1047 LEESLNKEKQVTEEVRKNIE--VRLKESAEFQTQLEKKLMEVEKEKQElqdDKRRAIESMEQQLSELKKTLSSVQNEVQ- 1123
Cdd:PRK03918  474 KERKLRKELRELEKVLKKESelIKLKELAEQLKELEEKLKKYNLEELE---KKAEEYEKLKEKLIKLKGEIKSLKKELEk 550

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1124 -EALQRASTALSNE-QQARRDCQEQAKIAVEAQNKYERELmlhAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLE 1201
Cdd:PRK03918  551 lEELKKKLAELEKKlDELEEELAELLKELEELGFESVEEL---EERLKELEPFYNEYLELKDAEKELEREEKELKKLEEE 627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1202 CKASWEERERMLKDeVSKCVCRCEDLEKqnRLLHDQIEKLSDKVVASVKEgvQGPLNVSLSEEGKSQEQILEILRFIRRE 1281
Cdd:PRK03918  628 LDKAFEELAETEKR-LEELRKELEELEK--KYSEEEYEELREEYLELSRE--LAGLRAELEELEKRREEIKKTLEKLKEE 702

                         570
                  ....*....|....*
gi 119611609 1282 K-EIAETRFEVAQVE 1295
Cdd:PRK03918  703 LeEREKAKKELEKLE 717
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
105-447 5.24e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  105 LADQQSEIDGLKGRHEKF------KVESEQQYFEIEKRLSHSQERL---------VNETRECQSLRLELEKLNNQLKALT 169
Cdd:COG4717    73 LKELEEELKEAEEKEEEYaelqeeLEELEEELEELEAELEELREELeklekllqlLPLYQELEALEAELAELPERLEELE 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  170 EKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDL----IRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDEL 245
Cdd:COG4717   153 ERLEELRELEEELEELEAELAELQEELEELLEQLslatEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  246 QASDVSVKAKKRLEQEKELL--------HSQNTWLNTELKTKTDELLALG---------------REKGNEILELKCNLE 302
Cdd:COG4717   233 ENELEAAALEERLKEARLLLliaaallaLLGLGGSLLSLILTIAGVLFLVlgllallflllarekASLGKEAEELQALPA 312

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  303 NKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH--NELNAHIKLSNLYKSAADDSEAKSNELTR 380
Cdd:COG4717   313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAEAGVEDEEELRAALE 392

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609  381 AVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML-EKIGRLEKEL-ENANDLLSATKRKGAILSE 447
Cdd:COG4717   393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEELeEELEELEEELeELEEELEELREELAELEAE 461
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1127-1694 5.42e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 5.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1127 QRASTALSNEQQARRDCQEQ-AKIAVEAQNKYERELmlhaadVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKAS 1205
Cdd:PRK02224  169 ERASDARLGVERVLSDQRGSlDQLKAQIEEKEEKDL------HERLNGLESELAELDEEIERYEEQREQARETRDEADEV 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1206 WEERERmlkdevskcvcRCEDLEKqnrlLHDQIEKLSDKVVASVKEgvqgplNVSLSEEGKSQEQILEILRfIRREKEIA 1285
Cdd:PRK02224  243 LEEHEE-----------RREELET----LEAEIEDLRETIAETERE------REELAEEVRDLRERLEELE-EERDDLLA 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1286 ETRFEVAQVESLRyrQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTEtmnvvmETNKMLREEKERLEQDL 1365
Cdd:PRK02224  301 EAGLDDADAEAVE--ARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE------ERAEELREEAAELESEL 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1366 QQMQAKVRKLELDILPLQEANAELSEK-------SGMLQAEKKLLEEDVKRWKARNQHLVS--QQKDPDTEEYRKLLSEK 1436
Cdd:PRK02224  373 EEAREAVEDRREEIEELEEEIEELRERfgdapvdLGNAEDFLEELREERDELREREAELEAtlRTARERVEEAEALLEAG 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1437 EVHT------------------KRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEdLNKVRTEKETIQKDLDAKIID 1498
Cdd:PRK02224  453 KCPEcgqpvegsphvetieedrERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEELIAERRET 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1499 IQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMEtsaqSSGDHQEQHVSV-QEMQELKETLNQAETKSKSL------ESQ 1571
Cdd:PRK02224  532 IEEKRERAEELRERAAELEAEAEEKREAAAEAEE----EAEEAREEVAELnSKLAELKERIESLERIRTLLaaiadaEDE 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1572 VENLQ---KTLSEKETEARN----LQEQTVQLQSEL--SRLRQDLQDRTTQEEQLRQ------QITEKEEKTRKAIVAAK 1636
Cdd:PRK02224  608 IERLRekrEALAELNDERRErlaeKRERKRELEAEFdeARIEEAREDKERAEEYLEQveekldELREERDDLQAEIGAVE 687

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609 1637 SKIAHLAGVKDQLtKENEELKQRNGALDQQKDELDVRITALKSQYEGR-ISRLERELRE 1694
Cdd:PRK02224  688 NELEELEELRERR-EALENRVEALEALYDEAEELESMYGDLRAELRQRnVETLERMLNE 745
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 741-1696 7.22e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 58.26  E-value: 7.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   741 IEAKAALKQLQEIFENYKKEKAENEKIQNEQ------LEKLQEQVTDLRSQNTKI--------------STQLDFASKRY 800
Cdd:pfam01576   96 NEKKKMQQHIQDLEEQLDEEEAARQKLQLEKvtteakIKKLEEDILLLEDQNSKLskerklleerisefTSNLAEEEEKA 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   801 EMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLA-----VAEVRAENLKKEKEmlklsevrlsq 875
Cdd:pfam01576  176 KSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAelqaqIAELRAQLAKKEEE----------- 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   876 qresllaeqrgqnllltnlqtIQGILERSETETKQRLSSQ--IEKLEHEISHLKKKLENEVEQRHTLT---RNLDVQLLD 950
Cdd:pfam01576  245 ---------------------LQAALARLEEETAQKNNALkkIRELEAQISELQEDLESERAARNKAEkqrRDLGEELEA 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   951 TKRQLDTETNLHLNTKELLKNAQKEIATLKQHLS----NMEVQVASQSSQRTgkgqpsnkEDVDDLVSQLrqteEQVNDL 1026
Cdd:pfam01576  304 LKTELEDTLDTTAAQQELRSKREQEVTELKKALEeetrSHEAQLQEMRQKHT--------QALEELTEQL----EQAKRN 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1027 KERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKEsaefqtqLEKKLMEVEKEKQELQDDKRR------- 1099
Cdd:pfam01576  372 KANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQE-------LQARLSESERQRAELAEKLSKlqseles 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1100 ---AIESMEQQLSELKKTLSSVQNE---VQEALQRA-------STALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAA 1166
Cdd:pfam01576  445 vssLLNEAEGKNIKLSKDVSSLESQlqdTQELLQEEtrqklnlSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQA 524

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1167 dveALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERmlkdevskcvcRCEDLEKQNRLLHDQIEKLsdkvv 1246
Cdd:pfam01576  525 ---QLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAA-----------AYDKLEKTKNRLQQELDDL----- 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1247 aSVKEGVQGPLNVSLSEEGKSQEQILeilrfirrekeiAETRFEVAQVESLRYRqrvellerelqelqdslnAEREKVQV 1326
Cdd:pfam01576  586 -LVDLDHQRQLVSNLEKKQKKFDQML------------AEEKAISARYAEERDR------------------AEAEAREK 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1327 TAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1406
Cdd:pfam01576  635 ETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDA 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1407 VKRWKARNQHLVSQQKdpdteeyRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKE 1486
Cdd:pfam01576  715 KLRLEVNMQALKAQFE-------RDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQID 787

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1487 TIQKDLDakiidiqEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVsvqEMQELKETLNQAETKSK 1566
Cdd:pfam01576  788 AANKGRE-------EAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEA---ELLQLQEDLAASERARR 857

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1567 SLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLR---QQITEKEEKTRKAIVAAKSKIAHLA 1643
Cdd:pfam01576  858 QAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNdrlRKSTLQVEQLTTELAAERSTSQKSE 937

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....
gi 119611609  1644 GVKDQLTKENEELKQRNGALDQQ-KDELDVRITALKSQYEGRISRLERELREHQ 1696
Cdd:pfam01576  938 SARQQLERQNKELKAKLQEMEGTvKSKFKSSIAALEAKIAQLEEQLEQESRERQ 991
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1496-1695 9.03e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 9.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1496 IIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDkvMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENL 1575
Cdd:COG4913   244 LEDAREQIELLEPIRELAERYAAARERLAELEY--LRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1576 QKTLSEKETEARN--------LQEQTVQLQSELSRLRqdlQDRTTQEEQLRqQITEKEEKTRKAIVAAKSKIAHLAGVKD 1647
Cdd:COG4913   322 REELDELEAQIRGnggdrleqLEREIERLERELEERE---RRRARLEALLA-ALGLPLPASAEEFAALRAEAAALLEALE 397

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 119611609 1648 QLTKENE----ELKQRNGALDQQKDELDVRITAL---KSQYEGRISRLERELREH 1695
Cdd:COG4913   398 EELEALEealaEAEAALRDLRRELRELEAEIASLerrKSNIPARLLALRDALAEA 452
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 891-1604 1.06e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.54  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   891 LTNLQTIQGIL-ERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNlhlNTKELL 969
Cdd:pfam12128  227 IRDIQAIAGIMkIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDD---QWKEKR 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   970 KNAQKEIATLKQHLSNMEVQVASQSSQRtGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKtstsnveqyqamvtSLEE 1049
Cdd:pfam12128  304 DELNGELSAADAAVAKDRSELEALEDQH-GAFLDADIETAAADQEQLPSWQSELENLEERLK--------------ALTG 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1050 SLNKEKQVTEEVRKNIEVRLK-ESAEFQTQLEKKLMEVEKEKQELQDDkrraiesMEQQLSELKKTLSSVQNEVQEALQR 1128
Cdd:pfam12128  369 KHQDVTAKYNRRRSKIKEQNNrDIAGIKDKLAKIREARDRQLAVAEDD-------LQALESELREQLEAGKLEFNEEEYR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1129 ASTALSNEQ------QARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMasvRQHLEETTQKAESQLLEC 1202
Cdd:pfam12128  442 LKSRLGELKlrlnqaTATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKR---RDQASEALRQASRRLEER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1203 KASWEERERMLKDEVSKCVcrcEDLEKQNRLLHDQIEKlsdkvVASVKEGVQGPLNVSLSEEGKSQEQILEILrfirrek 1282
Cdd:pfam12128  519 QSALDELELQLFPQAGTLL---HFLRKEAPDWEQSIGK-----VISPELLHRTDLDPEVWDGSVGGELNLYGV------- 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1283 eiaetRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQ-HEELMKKTETMNVVMETNKMLREEKERL 1361
Cdd:pfam12128  584 -----KLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQaNGELEKASREETFARTALKNARLDLRRL 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1362 EQDLQQMQAKVRKleldilPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVhtk 1441
Cdd:pfam12128  659 FDEKQSEKDKKNK------ALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA--- 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1442 riqqlteEIGRLKAEIARSNASLTNNQNLIQS-LKEDLNKVRTEKETIQKdLDAKIIDIQEKVKTITQVKKIGRRYKTQY 1520
Cdd:pfam12128  730 -------QLALLKAAIAARRSGAKAELKALETwYKRDLASLGVDPDVIAK-LKREIRTLERKIERIAVRRQEVLRYFDWY 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1521 eelkaqqdkvmetsaqssgdhqeQHVSVQEMQELKETLNQAETKSKSLESQVENLQKT----LSEKETEARNLQEQTVQL 1596
Cdd:pfam12128  802 -----------------------QETWLQRRPRLATQLSNIERAISELQQQLARLIADtklrRAKLEMERKASEKQQVRL 858


                   ....*...
gi 119611609  1597 QSELSRLR 1604
Cdd:pfam12128  859 SENLRGLR 866
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1443-1719 1.27e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1443 IQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEE 1522
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1523 LKAQqdkvmetsaqssgdhqeqhvsVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSR 1602
Cdd:TIGR04523  206 LKKK---------------------IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK 264

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1603 LRQDLQDRTTQEEQLRQQITEKEEKTRKaivaAKSKIAHLAGVKDQ-LTKE-NEELKQRNGALDQQKDELDvRITALKSQ 1680
Cdd:TIGR04523  265 IKKQLSEKQKELEQNNKKIKELEKQLNQ----LKSEISDLNNQKEQdWNKElKSELKNQEKKLEEIQNQIS-QNNKIISQ 339

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 119611609  1681 YEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQ 1719
Cdd:TIGR04523  340 LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE 378
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 108-399 1.47e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   108 QQSEIDglkgRHEKFKVESEQQYFEIEK---RLSHSQERLVNETRECQSLRLELE-KLNNQLKALTEKNKELEIAQDRNI 183
Cdd:TIGR02168  675 RRREIE----ELEEKIEELEEKIAELEKalaELRKELEELEEELEQLRKELEELSrQISALRKDLARLEAEVEQLEERIA 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   184 AIQSQFTRTKEELEAEKRDLIRTNERLS---QELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS-DVSVKAKKRLE 259
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAeaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEaANLRERLESLE 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   260 QEKELLHSQNTWLNTELKTKTDELLALGRE---KGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKL 336
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119611609   337 KEAKEQQASMEEKFH------NELNAHI-----KLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAI 399
Cdd:TIGR02168  911 SELRRELEELREKLAqlelrlEGLEVRIdnlqeRLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1549-1698 1.49e-07

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 54.93  E-value: 1.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1549 QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLR--QDLQDRTTQEEQLRQQITEKEE 1626
Cdd:COG1579    31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnKEYEALQKEIESLKRRISDLED 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119611609 1627 KTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQER 1698
Cdd:COG1579   111 EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPELLALYER 182
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 105-1124 1.63e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 57.37  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   105 LADQQSEIDglkgrhekfKVESEQQYFEIEKRLSHSQErLVNETRECQSLRLELEK-----LNNQLKALTE--KNKELEI 177
Cdd:TIGR01612  698 LDDLKSKID---------KEYDKIQNMETATVELHLSN-IENKKNELLDIIVEIKKhihgeINKDLNKILEdfKNKEKEL 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   178 AQDRNiaiqsQFTRTKEELEAEKRDL--IRT------------NERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLD 243
Cdd:TIGR01612  768 SNKIN-----DYAKEKDELNKYKSKIseIKNhyndqinidnikDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKD 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   244 E-LQASDVSVKAKKRLEQEKELLHSQNTWLNTELKTK-TDELLALGREKGNEILELKCNLENKKEEVSrleEQMNGLKTS 321
Cdd:TIGR01612  843 DfLNKVDKFINFENNCKEKIDSEHEQFAELTNKIKAEiSDDKLNDYEKKFNDSKSLINEINKSIEEEY---QNINTLKKV 919

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   322 NEHLqKHVEDLLTKLKEAKEQQASMEEKFHNELNAhIKLSNLY-KSAADDSEaksNELTRAVEELHKLLKEAGeankaiq 400
Cdd:TIGR01612  920 DEYI-KICENTKESIEKFHNKQNILKEILNKNIDT-IKESNLIeKSYKDKFD---NTLIDKINELDKAFKDAS------- 987

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   401 dhlLEVEQSKDQmekEMLEKIGRLEKELenandllsaTKRKGAILSEEELAAMSPTAAAVAKIVK-----PGMKL---TE 472
Cdd:TIGR01612  988 ---LNDYEAKNN---ELIKYFNDLKANL---------GKNKENMLYHQFDEKEKATNDIEQKIEDankniPNIEIaihTS 1052

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   473 LYNAYVEtqdqllLEKLENKRINKYLDEIVKEVEakapilkrqreeyeraqkavasLSVKLEQAMKEIQRLQEDTDKANK 552
Cdd:TIGR01612 1053 IYNIIDE------IEKEIGKNIELLNKEILEEAE----------------------INITNFNEIKEKLKHYNFDDFGKE 1104

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   553 QSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSssEVISQHLVSYRNIEELQQQNQRLLVAL 632
Cdd:TIGR01612 1105 ENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDL--EDVADKAISNDDPEEIEKKIENIVTKI 1182

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   633 RElgetreREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVS 712
Cdd:TIGR01612 1183 DK------KKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIK 1256

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   713 LASTPKRPSTSQTVSTPAPVPVIESTEA------IEAKAALKQLQEIFENYKK--EKAENEKIQNEQLEKLQEQVTDLRS 784
Cdd:TIGR01612 1257 EKSPEIENEMGIEMDIKAEMETFNISHDddkdhhIISKKHDENISDIREKSLKiiEDFSEESDINDIKKELQKNLLDAQK 1336

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   785 QNTKISTQLDFASKRYEMLQ--------DNVEGYRREItslHERNQKLTATTQKQEQIINTMTQDLrganeKLAVAEVRA 856
Cdd:TIGR01612 1337 HNSDINLYLNEIANIYNILKlnkikkiiDEVKEYTKEI---EENNKNIKDELDKSEKLIKKIKDDI-----NLEECKSKI 1408

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   857 ENLKKEKEMLKLSEvRLSQQRESLLAEQRGQNLLLTNlqtiqgilERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQ 936
Cdd:TIGR01612 1409 ESTLDDKDIDECIK-KIKELKNHILSEESNIDTYFKN--------ADENNENVLLLFKNIEMADNKSQHILKIKKDNATN 1479

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   937 RHTLTRNLDVQLLDTKRQLDTETNLHLN----TKELLKNAQKEIATLKQHLSNMEVQVA-SQSSQRTGKGQPSNKEDVDD 1011
Cdd:TIGR01612 1480 DHDFNINELKEHIDKSKGCKDEADKNAKaiekNKELFEQYKKDVTELLNKYSALAIKNKfAKTKKDSEIIIKEIKDAHKK 1559

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1012 LVSQLRQTEEQVNDLKERLKT----STSNVEQYQAMV---TSLEESLNKEKQVTEeVRKNIEVRLKESAEFQTQL----- 1079
Cdd:TIGR01612 1560 FILEAEKSEQKIKEIKKEKFRieddAAKNDKSNKAAIdiqLSLENFENKFLKISD-IKKKINDCLKETESIEKKIssfsi 1638

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....
gi 119611609  1080 ---EKKLMEVEKEKQELQD------DKRRAIESMEQQLSELKKTLSSVQNEVQE 1124
Cdd:TIGR01612 1639 dsqDTELKENGDNLNSLQEfleslkDQKKNIEDKKKELDELDSEIEKIEIDVDQ 1692
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 498-1111 1.77e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  498 LDEIVKEVEAKAPILKRQREEYERAQ--------KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVK 569
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERYRelkeelkeLEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  570 DLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhlvsyRNIEELQQQNQRLLVALRELgetrereeqettSS 649
Cdd:COG1196   271 ELRLELEELELELEEAQAEEYELLAELARLE---------------QDIARLEERRRELEERLEEL------------EE 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  650 KITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTvstp 729
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA---- 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  730 apvpvIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEG 809
Cdd:COG1196   400 -----AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  810 YRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVR------AENLKKEKEMLKLSEVRLS-----QQRE 878
Cdd:COG1196   475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavAVLIGVEAAYEAALEAALAaalqnIVVE 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  879 SLLAEQRGQNLLLTNLQTIQGILErsetETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTE 958
Cdd:COG1196   555 DDEVAAAAIEYLKAAKAGRATFLP----LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA 630

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  959 TNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVE 1038
Cdd:COG1196   631 RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119611609 1039 QYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQddkrRAIESMEQQLSEL 1111
Cdd:COG1196   711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE----RELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 106-821 1.78e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 1.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  106 ADQQSEIDGLKGRHEKFKVESEQQyfEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRniai 185
Cdd:PTZ00121 1274 AEEARKADELKKAEEKKKADEAKK--AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA---- 1347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  186 qsqftrTKEELEAEKRDLIRTNERlSQELEYLTEDVKRLNEKLKEsnttKGELQLKLDElqasdvsvkAKKRLEQEKEll 265
Cdd:PTZ00121 1348 ------AKAEAEAAADEAEAAEEK-AEAAEKKKEEAKKKADAAKK----KAEEKKKADE---------AKKKAEEDKK-- 1405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  266 HSQNTWLNTELKTKTDELLALGREKGN-EILELKCNLENKKEEVSRLEEQmnglKTSNEHLQKHVEDlltkLKEAKEQQA 344
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAKKKAEEKKKaDEAKKKAEEAKKADEAKKKAEE----AKKAEEAKKKAEE----AKKADEAKK 1477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  345 SMEEKfhnelnahiKLSNLYKSAADDSEAKSNELTRAVEELHKL--LKEAGEANKAiqDHLLEVEQSKDQMEKEMLEKIG 422
Cdd:PTZ00121 1478 KAEEA---------KKADEAKKKAEEAKKKADEAKKAAEAKKKAdeAKKAEEAKKA--DEAKKAEEAKKADEAKKAEEKK 1546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  423 RLEkELENANDLLSATKRKGA--ILSEEELAAMSPTAAAVAKIVKPGmKLTELYNAYVETQDQLL--LEKLENKRINKyl 498
Cdd:PTZ00121 1547 KAD-ELKKAEELKKAEEKKKAeeAKKAEEDKNMALRKAEEAKKAEEA-RIEEVMKLYEEEKKMKAeeAKKAEEAKIKA-- 1622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  499 DEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMK--EIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIR 576
Cdd:PTZ00121 1623 EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKaaEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  577 vllmELEEARGNhviRDEEVSSADISSSSEVISQHLVSYRNIEElQQQNQRLLVALRELGETREREEQETTSSKITELQL 656
Cdd:PTZ00121 1703 ----KAEELKKK---EAEEKKKAEELKKAEEENKIKAEEAKKEA-EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  657 KLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILL------SQTTGVAIPLHASSLDDVSLASTPKRpSTSQTVSTPA 730
Cdd:PTZ00121 1775 KEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIeggkegNLVINDSKEMEDSAIKEVADSKNMQL-EEADAFEKHK 1853

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  731 PVPVIESTEAIEAKAAL---KQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDfaskRYEMLQDNV 807
Cdd:PTZ00121 1854 FNKNNENGEDGNKEADFnkeKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLD----KDEYIKRDA 1929

                         730
                  ....*....|....
gi 119611609  808 EGYRREITSLHERN 821
Cdd:PTZ00121 1930 EETREEIIKISKKD 1943
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 855-1696 1.92e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.72  E-value: 1.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   855 RAENLKKEKEMLKLSEVRLS--QQRESLLAEQRgqNLLLTNLQTIQGILERSEtETKQRLSSQIEKLEHEISHLKKKLEN 932
Cdd:pfam01576   10 KEEELQKVKERQQKAESELKelEKKHQQLCEEK--NALQEQLQAETELCAEAE-EMRARLAARKQELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   933 EVE---QRHTLTRNLDVQLLDTKRQLDTETNLHlntkellKNAQKEIATLKQHLSNMEVQVASQSSQRT--GKGQPSNKE 1007
Cdd:pfam01576   87 EEErsqQLQNEKKKMQQHIQDLEEQLDEEEAAR-------QKLQLEKVTTEAKIKKLEEDILLLEDQNSklSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1008 DVDDLVSQLRQTEEQVNDLkERLKTstsnveQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKES-------AEFQTQLE 1080
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSL-SKLKN------KHEAMISDLEERLKKEEKGRQELEKAKRKLEGEStdlqeqiAELQAQIA 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1081 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKKT--LSSVQNEVQEALQRASTALSNEQQARRDCQEQ------------ 1146
Cdd:pfam01576  233 ELRAQLAKKEEELQAALARLEEETAQKNNALKKIreLEAQISELQEDLESERAARNKAEKQRRDLGEElealkteledtl 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1147 --AKIAVEAQNKYERELML-----------HAADV--------EALQAAKEQVSKMASVRQHLEETTQKAESQLLE---- 1201
Cdd:pfam01576  313 dtTAAQQELRSKREQEVTElkkaleeetrsHEAQLqemrqkhtQALEELTEQLEQAKRNKANLEKAKQALESENAElqae 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1202 ------CKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVvasvkEGVQGPLNVSLSEEGKSQEQILEIL 1275
Cdd:pfam01576  393 lrtlqqAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSEL-----ESVSSLLNEAEGKNIKLSKDVSSLE 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1276 RFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVM----ETN 1351
Cdd:pfam01576  468 SQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLealeEGK 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1352 KMLREEKERLEQDLQQMQAKVRKLELDILPLQEanaELSEKSGMLQAEKKLLEEDVKRWKARNQHL-----VSQQKDPDT 1426
Cdd:pfam01576  548 KRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQ---ELDDLLVDLDHQRQLVSNLEKKQKKFDQMLaeekaISARYAEER 624

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1427 EEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTI 1506
Cdd:pfam01576  625 DRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEEL 704

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1507 T---QVKKIGR-RYKTQYEELKAQQDKVMETSAQSSGDHQEQHV-SVQEMQ-ELKETLNQA----------ETKSKSLES 1570
Cdd:pfam01576  705 EdelQATEDAKlRLEVNMQALKAQFERDLQARDEQGEEKRRQLVkQVRELEaELEDERKQRaqavaakkklELDLKELEA 784

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1571 QVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQlrqqiTEKEEKTRKA-IVAAKSKIAHLAGVKDQL 1649
Cdd:pfam01576  785 QIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKE-----SEKKLKNLEAeLLQLQEDLAASERARRQA 859

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 119611609  1650 TKENEELKQR--NGALDQQKDELDvritalKSQYEGRISRLERELREHQ 1696
Cdd:pfam01576  860 QQERDELADEiaSGASGKSALQDE------KRRLEARIAQLEEELEEEQ 902
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 155-1089 1.93e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 1.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   155 RLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRdlirtnerlsqeleyltedvkrlneklkesntt 234
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQL--------------------------------- 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   235 kgelqlkldelqasdvsvKAKKRLEQEKELLHSQNTWLNTELKTKTDELLAlgrekGNEILELKCNLENKKEEVSRLEEQ 314
Cdd:pfam02463  216 ------------------KEKLELEEEYLLYLDYLKLNEERIDLLQELLRD-----EQEEIESSKQEIEKEEEKLAQVLK 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   315 MNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLyksaadDSEAKSNELTRAVEELHKLLKEAGE 394
Cdd:pfam02463  273 ENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEK------EKKKAEKELKKEKEEIEELEKELKE 346

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   395 ANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLtely 474
Cdd:pfam02463  347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLK---- 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   475 nayvETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQS 554
Cdd:pfam02463  423 ----EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEER 498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   555 SVLERDNRRMEIQVKDLSQQIRVLLMELEEARGnhviRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRE 634
Cdd:pfam02463  499 SQKESKARSGLKVLLALIKDGVGGRIISAHGRL----GDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   635 LGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVaiplhaSSLDDVSLA 714
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE------SAKAKESGL 648

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   715 STPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKI-QNEQLEKLQEQVTDLRSQNTKISTQL 793
Cdd:pfam02463  649 RKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIkKKEQREKEELKKLKLEAEELLADRVQ 728

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   794 DFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAeVRAENLKKEKEMLKLSEVRL 873
Cdd:pfam02463  729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK-VEEEKEEKLKAQEEELRALE 807

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   874 SQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKR 953
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   954 QLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQP----SNKEDVDDLVSQLRQTEEQVNDLKER 1029
Cdd:pfam02463  888 LESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPeellLEEADEKEKEENNKEEEEERNKRLLL 967

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1030 LKTSTSNVEqyqamVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKE 1089
Cdd:pfam02463  968 AKEELGKVN-----LMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 755-1502 2.21e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 56.65  E-value: 2.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   755 ENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTAttqKQEQI 834
Cdd:pfam05483   63 EGLKDSDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSL---KLEEE 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   835 INTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSS 914
Cdd:pfam05483  140 IQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKE 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   915 QIEKleheISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNL---------HLNTKELLKNAQKEIATLKQHLSN 985
Cdd:pfam05483  220 DHEK----IQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLleesrdkanQLEEKTKLQDENLKELIEKKDHLT 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   986 MEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQ-TEEQVNDLKERLKTSTSN---VEQYQAMVTSLEESLNKEKQVTEEV 1061
Cdd:pfam05483  296 KELEDIKMSLQRSMSTQKALEEDLQIATKTICQlTEEKEAQMEELNKAKAAHsfvVTEFEATTCSLEELLRTEQQRLEKN 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1062 RKNIEVRLKESAEFQTQLEKklMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARR 1141
Cdd:pfam05483  376 EDQLKIITMELQKKSSELEE--MTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIH 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1142 DCQEQAKIAVEAQNKYERELmlhaadvealqaaKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKdEVSKCV 1221
Cdd:pfam05483  454 DLEIQLTAIKTSEEHYLKEV-------------EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTL-ELKKHQ 519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1222 CRCEDLEKQNRLLHDQIEKLSDKvvasvkegvqgplnvslseEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQ 1301
Cdd:pfam05483  520 EDIINCKKQEERMLKQIENLEEK-------------------EMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEY 580

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1302 RVELLERELQELQDSLNAEREKVQVTAKTMaqhEELMKKtetmnvvmetNKMLREEKERLEQDLQQMQAKVRKLELDILP 1381
Cdd:pfam05483  581 EVLKKEKQMKILENKCNNLKKQIENKNKNI---EELHQE----------NKALKKKGSAENKQLNAYEIKVNKLELELAS 647

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1382 LQEANAELSEKSGMLQAEKKLLEE----DVKRWKARNQHLVSQQKDPDTEEYRKL-----LSEKEVHT--KRIQQLTEEI 1450
Cdd:pfam05483  648 AKQKFEEIIDNYQKEIEDKKISEEklleEVEKAKAIADEAVKLQKEIDKRCQHKIaemvaLMEKHKHQydKIIEERDSEL 727

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609  1451 GRLKAEIARSNA-------SLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEK 1502
Cdd:pfam05483  728 GLYKNKEQEQSSakaaleiELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 889-1132 2.41e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  889 LLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRhtltRNLDVQLLDTKRQL-DTETNLHLNTKE 967
Cdd:COG4942     9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----AALERRIAALARRIrALEQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  968 lLKNAQKEIATLKQHLSNMEVQVASQ--SSQRTGKGQPS----NKEDVDDLVSQLRQTEEQVNDLKERLKTstsnVEQYQ 1041
Cdd:COG4942    85 -LAELEKEIAELRAELEAQKEELAELlrALYRLGRQPPLalllSPEDFLDAVRRLQYLKYLAPARREQAEE----LRADL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1042 AMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQddkrRAIESMEQQLSELKKTLSSVQNE 1121
Cdd:COG4942   160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA----AELAELQQEAEELEALIARLEAE 235

                         250
                  ....*....|.
gi 119611609 1122 VQEALQRASTA 1132
Cdd:COG4942   236 AAAAAERTPAA 246
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 890-1636 4.02e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 4.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   890 LLTNLQTIQGILERSETETKQRLSSQIEKLEHeishlKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELL 969
Cdd:TIGR04523   38 LEKKLKTIKNELKNKEKELKNLDKNLNKDEEK-----INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   970 KNAQKEIATLKQHLSNMEvqvasqssqrtgKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE 1049
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLE------------KQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1050 SLNKEKQVTEEVRKNIEVR------LKESAEFQTQLEKKLMEVEKEKQELQDDkrraIESMEQQLSELKKTLSSVQNEVQ 1123
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLelllsnLKKKIQKNKSLESQISELKKQNNQLKDN----IEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1124 EalqrastaLSNEQQARRDCQEQAKIAVEAQNKYERELMlhaadvEALQAAKEQVSKMASVRQhlEETTQKAESQLleck 1203
Cdd:TIGR04523  257 Q--------LKDEQNKIKKQLSEKQKELEQNNKKIKELE------KQLNQLKSEISDLNNQKE--QDWNKELKSEL---- 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1204 ASWEERERMLKDEVSKCvcrcedlEKQNRLLHDQIEKLSDKVVASVKEgvqgplNVSLSEEGKSQEQILEILrfirrEKE 1283
Cdd:TIGR04523  317 KNQEKKLEEIQNQISQN-------NKIISQLNEQISQLKKELTNSESE------NSEKQRELEEKQNEIEKL-----KKE 378

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1284 IAETRFEVAQVESlryrqrvellerelqelqdSLNAEREKVQVTAKTMAQHEELMKKtetmnvvmetnkmLREEKERLEQ 1363
Cdd:TIGR04523  379 NQSYKQEIKNLES-------------------QINDLESKIQNQEKLNQQKDEQIKK-------------LQQEKELLEK 426

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1364 DLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKArnqhlvsqqkdpdteEYRKLLSEKEVHTKRI 1443
Cdd:TIGR04523  427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR---------------SINKIKQNLEQKQKEL 491

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1444 QQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKdldaKIIDIQEKVKTITQVKKigrryKTQYEEL 1523
Cdd:TIGR04523  492 KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKES----KISDLEDELNKDDFELK-----KENLEKE 562

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1524 KAQQDKVMETSaqssgdHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRL 1603
Cdd:TIGR04523  563 IDEKNKEIEEL------KQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636

                          730       740       750
                   ....*....|....*....|....*....|...
gi 119611609  1604 RQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAK 1636
Cdd:TIGR04523  637 KSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIK 669
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1440-1676 4.04e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 4.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1440 TKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQ 1519
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1520 YEELKAQQDKVMETSAQSSGDHQEQHVSVQEmqelkeTLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSE 1599
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQPPLALLLSPE------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609 1600 LSRLRQDLQDRTTQEEQLRQQITEKEektrKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITA 1676
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQ----KLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 146-584 4.09e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 4.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   146 NETREcQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLN 225
Cdd:TIGR04523   31 QDTEE-KQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKIN 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   226 EKLKESNTTKGELQLKLDELqasdvsvkaKKRLEQEKELLhsqnTWLNTELKTKTDELLALGrEKGNEILELKCNLENKK 305
Cdd:TIGR04523  110 SEIKNDKEQKNKLEVELNKL---------EKQKKENKKNI----DKFLTEIKKKEKELEKLN-NKYNDLKKQKEELENEL 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   306 EEVSR--LEEQMNGLKTSNEHLQKHVedLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVE 383
Cdd:TIGR04523  176 NLLEKekLNIQKNIDKIKNKLLKLEL--LLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   384 ELHKLLKEAGEANKAIQDHLLEVEQSKDQMeKEMLEKIGRLEKELENAN-------------DLLSATKRKGAILSE--E 448
Cdd:TIGR04523  254 QLNQLKDEQNKIKKQLSEKQKELEQNNKKI-KELEKQLNQLKSEISDLNnqkeqdwnkelksELKNQEKKLEEIQNQisQ 332

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   449 ELAAMSPTAAAVAKIVKpgmKLTELYNAYVETQDQL-----LLEKLeNKRINKYLDEIvKEVEAKAPILKRQREEYERA- 522
Cdd:TIGR04523  333 NNKIISQLNEQISQLKK---ELTNSESENSEKQRELeekqnEIEKL-KKENQSYKQEI-KNLESQINDLESKIQNQEKLn 407

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119611609   523 ---QKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEE 584
Cdd:TIGR04523  408 qqkDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKV 472
PTZ00121 PTZ00121
MAEBL; Provisional
 353-1194 4.52e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  353 ELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMekemlekigrleKELENAN 432
Cdd:PTZ00121 1061 EAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAK------------KKAEDAR 1128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  433 DLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRInkylDEIVKEVEAKAPIL 512
Cdd:PTZ00121 1129 KAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKA----EELRKAEDARKAEA 1204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  513 KRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR-GNHVI 591
Cdd:PTZ00121 1205 ARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARkADELK 1284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  592 RDEEVSSADISSSSEVIsqhlvsyRNIEELQQQNQrllvalrelgetrereeqetTSSKITELQLKLESALTELEQLRKS 671
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEK-------KKADEAKKKAE--------------------EAKKADEAKKKAEEAKKKADAAKKK 1337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  672 RQHqmqlvdsivrqrdmyrillsqttgvaiplhASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQ 751
Cdd:PTZ00121 1338 AEE------------------------------AKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  752 EIFENYK--KEKAENEKIQNEQLEKLQE--QVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTAT 827
Cdd:PTZ00121 1388 EEKKKADeaKKKAEEDKKKADELKKAAAakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  828 TQKQEQIINTMTQDLRGANEklavAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQnllltnlqtiqgiLERSETE 907
Cdd:PTZ00121 1468 EAKKADEAKKKAEEAKKADE----AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK-------------ADEAKKA 1530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  908 TKQRLSSQIEKLEheishlKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKeiatlkqhlSNME 987
Cdd:PTZ00121 1531 EEAKKADEAKKAE------EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE---------ARIE 1595

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  988 VQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNvEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 1067
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE-EKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1068 RLKESAEFQTQLEKKLMEVEKEKQElqddKRRAIESMEQQLSELKKTLSSVQNEVQEALQRAstalsneQQARRDCQEQA 1147
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKKEAE----EAKKAEELKKKEAEEKKKAEELKKAEEENKIKA-------EEAKKEAEEDK 1743

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*...
gi 119611609 1148 KIAVEAQ-NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1194
Cdd:PTZ00121 1744 KKAEEAKkDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEK 1791
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1053-1705 4.55e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 4.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1053 KEKQVTEEVRKNIEVRLKESAEFQTQL------EKKLMEVEKEKQE---LQDDKRRAIESM-----EQQLSELKKTLSSV 1118
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLeelklqELKLKEQAKKALEyyqLKEKLELEEEYLlyldyLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1119 QNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMAS----VRQHLEETTQK 1194
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVddeeKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1195 AESQLLECKASWEERERMLKdEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNvSLSEEGKSQEQILEI 1274
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELK-ELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS-AAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1275 LRFIRREKEIAETRFEVAQVESLRYRQRVELLEREL--QELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNK 1352
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIelKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1353 M-LREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQ-QKDPDTEEYR 1430
Cdd:pfam02463  484 EqLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEvSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1431 KLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKdLDAKIIDIQEKVKTITQVK 1510
Cdd:pfam02463  564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK-VVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1511 KIGRRYKTQYEELKAQQDKVmETSAQSSGDHQEQHvsvqEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQ 1590
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKS-EVKASLSELTKELL----EIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1591 EQTVQLQSELSRL-------RQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGAL 1663
Cdd:pfam02463  718 EAEELLADRVQEAqdkineeLKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 119611609  1664 DQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDE 1705
Cdd:pfam02463  798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELA 839
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 89-1654 5.71e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.44  E-value: 5.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    89 ELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQ----QYF-EIEKRLSHSQERLVNETREcqslrlELEK-LN 162
Cdd:TIGR01612  956 ESNLIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKNneliKYFnDLKANLGKNKENMLYHQFD------EKEKaTN 1029

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   163 NQLKALTEKNKELEiaqDRNIAIQSQFTRTKEELEAEkrdlirtnerLSQELEYLTEDVKrlnEKLKESNTTKGELQLKL 242
Cdd:TIGR01612 1030 DIEQKIEDANKNIP---NIEIAIHTSIYNIIDEIEKE----------IGKNIELLNKEIL---EEAEINITNFNEIKEKL 1093

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   243 DELQASDVSVKAKKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLEN---------KKEEVSRLEE 313
Cdd:TIGR01612 1094 KHYNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDledvadkaiSNDDPEEIEK 1173

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   314 QMNGLKTS---NEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLK 390
Cdd:TIGR01612 1174 KIENIVTKidkKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLD 1253

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   391 EAGEANKAIQdhlleveqskDQMEKEMLEKigrleKELENANdLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKL 470
Cdd:TIGR01612 1254 EIKEKSPEIE----------NEMGIEMDIK-----AEMETFN-ISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEE 1317

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   471 TELYNAYVETQDQLLLEKLENKRINKYLDEI-----------VKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKE 539
Cdd:TIGR01612 1318 SDINDIKKELQKNLLDAQKHNSDINLYLNEIaniynilklnkIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKD 1397

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   540 IQRLQE------------DTDKANKQSSVL-------ERDNRRMEIQVKDLSQQIRVLLMELEEA--RGNHVIRDE---- 594
Cdd:TIGR01612 1398 DINLEEckskiestlddkDIDECIKKIKELknhilseESNIDTYFKNADENNENVLLLFKNIEMAdnKSQHILKIKkdna 1477

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   595 ------------EVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALR---ELGETREREEQETTSSKI------TE 653
Cdd:TIGR01612 1478 tndhdfninelkEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNkysALAIKNKFAKTKKDSEIIikeikdAH 1557

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   654 LQLKLESALTElEQLRKSRQHQMQLVDSIVRQRDmyrillSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVP 733
Cdd:TIGR01612 1558 KKFILEAEKSE-QKIKEIKKEKFRIEDDAAKNDK------SNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIE 1630

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   734 VIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMlqdnveGYRRE 813
Cdd:TIGR01612 1631 KKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEI------GIIEK 1704

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   814 ITSLHERNQ-KLTATTQKQEQIINTM-----TQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRL----SQQRESLLAE 883
Cdd:TIGR01612 1705 IKEIAIANKeEIESIKELIEPTIENLissfnTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAgcleTVSKEPITYD 1784

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   884 Q------RGQNLLLTNLQtiqgilerSETETKQRLSS-QIEKLEHEISHLKKKLENEVeqrhtltrnldvqlldtkrqlD 956
Cdd:TIGR01612 1785 EikntriNAQNEFLKIIE--------IEKKSKSYLDDiEAKEFDRIINHFKKKLDHVN---------------------D 1835

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   957 TETNLHLNTKELLKNAQKEIATLKQH-----LSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKErlk 1031
Cdd:TIGR01612 1836 KFTKEYSKINEGFDDISKSIENVKNStdenlLFDILNKTKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINIQIQ--- 1912

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1032 tSTSNVEQYQAMVTSLEESLNKEKQVT------EEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQE---LQDDKRRAIE 1102
Cdd:TIGR01612 1913 -NNSGIDLFDNINIAILSSLDSEKEDTlkfipsPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQDtlnIIFENQQLYE 1991

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1103 SMeQQLSELKKTLSSVQ-------NEVQEALQRAS-----TALSNEQQARRDCQEQAKIAvEAQNKYERELMLHAADVEa 1170
Cdd:TIGR01612 1992 KI-QASNELKDTLSDLKykkekilNDVKLLLHKFDelnklSCDSQNYDTILELSKQDKIK-EKIDNYEKEKEKFGIDFD- 2068

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1171 LQAAKEQVSKMASVRQHLEETTQKAESQLLEckaSWEERERMLKDEvskcvcrcEDLEKQNRLLHDQIEKLSDKVVAsvK 1250
Cdd:TIGR01612 2069 VKAMEEKFDNDIKDIEKFENNYKHSEKDNHD---FSEEKDNIIQSK--------KKLKELTEAFNTEIKIIEDKIIE--K 2135

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1251 EGVQGPLN-----------VSLSEEGKSqeQILEILRFIRREKEIAETRFEVAQVESlryrqrvellerelqelqDSLNA 1319
Cdd:TIGR01612 2136 NDLIDKLIemrkecllfsyATLVETLKS--KVINHSEFITSAAKFSKDFFEFIEDIS------------------DSLND 2195

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1320 EREKVQvTAKTMAQHEELMkKTETMNVVMETNKMLREEKERLEQ----------DLQQMQAKVrkLELDILPLQEANAEL 1389
Cdd:TIGR01612 2196 DIDALQ-IKYNLNQTKKHM-ISILADATKDHNNLIEKEKEATKIinnltelftiDFNNADADI--LHNNKIQIIYFNSEL 2271

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1390 sEKSgmLQAEKKLLEEdVKRWKARNQHL-------VSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNA 1462
Cdd:TIGR01612 2272 -HKS--IESIKKLYKK-INAFKLLNISHinekyfdISKEFDNIIQLQKHKLTENLNDLKEIDQYISDKKNIFLHALNENT 2347

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1463 SLtnNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQV-KKIGR--RYKTQYEelkaQQDKVMETSAQssg 1539
Cdd:TIGR01612 2348 NF--NFNALKEIYDDIINRENKADEIENINNKENENIMQYIDTITKLtEKIQDilIFVTTYE----NDNNIIKQHIQ--- 2418

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1540 DHQEQHVS---------VQEMQELKETLNQAETKSKSlESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQD- 1609
Cdd:TIGR01612 2419 DNDENDVSkikdnlkktIQSFQEILNKIDEIKAQFYG-GNNINNIIITISQNANDVKNHFSKDLTIENELIQIQKRLEDi 2497

                         1690      1700      1710      1720
                   ....*....|....*....|....*....|....*....|....*
gi 119611609  1610 RTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGvKDQLTKENE 1654
Cdd:TIGR01612 2498 KNAAHEIRSEQITKYTNAIHNHIEEQFKKIENNSN-KDEVYKINE 2541
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
737-1214 7.86e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 7.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  737 STEAIEAKaaLKQLQEIFENYKKEKAENEKIQNE--QLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREI 814
Cdd:PRK03918  253 SKRKLEEK--IRELEERIEELKKEIEELEEKVKElkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  815 TSLHERNQKLTATTQKQEQI---INTMTQDLRgANEKLAVAEVRAENLKKEKEMLKLSEVrlsqQRESLLAEQRGQNLLl 891
Cdd:PRK03918  331 KELEEKEERLEELKKKLKELekrLEELEERHE-LYEEAKAKKEELERLKKRLTGLTPEKL----EKELEELEKAKEEIE- 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  892 tnlqtiqgiLERSE-TETKQRLSSQIEKLEHEISHLKK--------KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLH 962
Cdd:PRK03918  405 ---------EEISKiTARIGELKKEIKELKKAIEELKKakgkcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKE 475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  963 LNTKELLKNAQKEIATLKQHLSNMEvqVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQA 1042
Cdd:PRK03918  476 RKLRKELRELEKVLKKESELIKLKE--LAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1043 MVTSLEEsLNKEKQVTEEVRKNIEVRLKESAefqtqlEKKLMEVEKEKQELQDDKRRAIE--SMEQQLSELKKTLSSVQN 1120
Cdd:PRK03918  554 LKKKLAE-LEKKLDELEEELAELLKELEELG------FESVEELEERLKELEPFYNEYLElkDAEKELEREEKELKKLEE 626

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1121 EVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAAdvEALQAAKEQVSKMASVRQHLEETTQKAESQLL 1200
Cdd:PRK03918  627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELS--RELAGLRAELEELEKRREEIKKTLEKLKEELE 704

                         490
                  ....*....|....
gi 119611609 1201 ECKASWEERERMLK 1214
Cdd:PRK03918  705 EREKAKKELEKLEK 718
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 101-381 7.86e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 7.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   101 LEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLvneTRECQSLRLELEKLNNQLKaltEKNKELEIAQD 180
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV---KEKIGELEAEIASLERSIA---EKERELEDAEE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   181 RNIAIQSQFTRTKEELEAEKRDLirtnERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQasDVSVKAKKRLEQ 260
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREI----EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR--DELKDYREKLEK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   261 EKELLHsqntwlntELKTKTDELLALGREKGNEILELkcnlenkKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAK 340
Cdd:TIGR02169  397 LKREIN--------ELKRELDRLQEELQRLSEELADL-------NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLA 461

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 119611609   341 EQQASMEEKfhnelnaHIKLSNLYKSAADDSEAKSNELTRA 381
Cdd:TIGR02169  462 ADLSKYEQE-------LYDLKEEYDRVEKELSKLQRELAEA 495
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 693-1501 8.55e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 8.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   693 LSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQL 772
Cdd:pfam15921   19 ITSNRGSSSPFFVSSIRGTIIENTSSTGTFTQIPIFPKYEVELDSPRKIIAYPGKEHIERVLEEYSHQVKDLQRRLNESN 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   773 EKLQEQVTDLRSQNTKISTQLdfasKRYEMLQDNVEGYRREitslhernqkltaTTQKQEQIINTMTQdlrganeklAVA 852
Cdd:pfam15921   99 ELHEKQKFYLRQSVIDLQTKL----QEMQMERDAMADIRRR-------------ESQSQEDLRNQLQN---------TVH 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   853 EVRAENLKKEkEMLKLSEVRLSQQRESLLAEQrgqnlllTNLQTIQGILERSETETKQRL------------------SS 914
Cdd:pfam15921  153 ELEAAKCLKE-DMLEDSNTQIEQLRKMMLSHE-------GVLQEIRSILVDFEEASGKKIyehdsmstmhfrslgsaiSK 224

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   915 QIEKLEHEISHLKKKL---ENEVEQRHTLTRNlDVQLLDTKRQLDTEtnlhlntkELLKNAQKEIATLKQHLSNMEVQVA 991
Cdd:pfam15921  225 ILRELDTEISYLKGRIfpvEDQLEALKSESQN-KIELLLQQHQDRIE--------QLISEHEVEITGLTEKASSARSQAN 295

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   992 S-QSSQRTGKGQPSNKEDVddLVSQLRQTEEQVNDLKERLKTSTsnvEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLK 1070
Cdd:pfam15921  296 SiQSQLEIIQEQARNQNSM--YMRQLSDLESTVSQLRSELREAK---RMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1071 ESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQ------LSELKKTLSSVQNEVQ--EALQRAstalsneqqARRD 1142
Cdd:pfam15921  371 ESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDtgnsitIDHLRRELDDRNMEVQrlEALLKA---------MKSE 441

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1143 CQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLK---DEVSK 1219
Cdd:pfam15921  442 CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEatnAEITK 521

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1220 CVCRCeDLEKQ---------NRLLHDQIE----KLS----DKVVASVKEGVQGPLNVsLSEEGKSQEQILeiLRFIRREK 1282
Cdd:pfam15921  522 LRSRV-DLKLQelqhlknegDHLRNVQTEcealKLQmaekDKVIEILRQQIENMTQL-VGQHGRTAGAMQ--VEKAQLEK 597

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1283 EIAETRFEVAQVESLR------YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTET----MNVVMETNK 1352
Cdd:pfam15921  598 EINDRRLELQEFKILKdkkdakIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTsrneLNSLSEDYE 677

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1353 MLR-------EEKE----RLEQDLQQMQAKVRKLELDILPLQEANA-----------ELSEKSGM---LQAEKKLLEEDV 1407
Cdd:pfam15921  678 VLKrnfrnksEEMEtttnKLKMQLKSAQSELEQTRNTLKSMEGSDGhamkvamgmqkQITAKRGQidaLQSKIQFLEEAM 757

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1408 ------KRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQslkedlnkv 1481
Cdd:pfam15921  758 tnankeKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ--------- 828

                          890       900
                   ....*....|....*....|
gi 119611609  1482 RTEKETIQKDLDaKIIDIQE 1501
Cdd:pfam15921  829 RQEQESVRLKLQ-HTLDVKE 847
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1268-1705 9.97e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.39  E-value: 9.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1268 QEQILEILRFIRREKEIAETRFEVAQVEsLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKtetmnvv 1347
Cdd:COG4717    52 EKEADELFKPQGRKPELNLKELKELEEE-LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK------- 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1348 METNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEanaelseksgmLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTE 1427
Cdd:COG4717   124 LLQLLPLYQELEALEAELAELPERLEELEERLEELRE-----------LEEELEELEAELAELQEELEELLEQLSLATEE 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1428 EYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEdlnkvrtEKETIQKDLDAKIIDIqekvkTIT 1507
Cdd:COG4717   193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL-------EERLKEARLLLLIAAA-----LLA 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1508 QVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEAR 1587
Cdd:COG4717   261 LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELL 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1588 NLQEQTVQLQSELSRLRQDlqdrtTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQK 1667
Cdd:COG4717   341 ELLDRIEELQELLREAEEL-----EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELL 415

                         410       420       430
                  ....*....|....*....|....*....|....*....
gi 119611609 1668 DELDVRITAL-KSQYEGRISRLERELREHQERHLEQRDE 1705
Cdd:COG4717   416 GELEELLEALdEEELEEELEELEEELEELEEELEELREE 454
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1001-1612 1.09e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 54.14  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1001 GQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQamvtSLEESLNKEKQVTEEVRKNIEvrlkESAEFQTQLE 1080
Cdd:PRK01156  146 GDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNID----YLEEKLKSSNLELENIKKQIA----DDEKSHSITL 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1081 KKLMEVEKEKQELQDDKRRAIESMeQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERE 1160
Cdd:PRK01156  218 KEIERLSIEYNNAMDDYNNLKSAL-NELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNY 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1161 LMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAEsqllECKASWEERERMLKdevskcvcRCEDLEKQnrllHDQIEK 1240
Cdd:PRK01156  297 INDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLS----VLQKDYNDYIKKKS--------RYDDLNNQ----ILELEG 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1241 LSDKVVASVKEGVQgpLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAE 1320
Cdd:PRK01156  361 YEMDYNSYLKSIES--LKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALREN 438

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1321 REKVqvtaktmaqhEELMKKTETMNVVMETNKMLREEKER-----LEQDLQQMQAKVRKLELDILPLQEanaelsEKSGM 1395
Cdd:PRK01156  439 LDEL----------SRNMEMLNGQSVCPVCGTTLGEEKSNhiinhYNEKKSRLEEKIREIEIEVKDIDE------KIVDL 502

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1396 LQAEKKLLEEDVKRWKARNQHLVSQQKDPdTEEYRKLLSEKEVHTKrIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1475
Cdd:PRK01156  503 KKRKEYLESEEINKSINEYNKIESARADL-EDIKIKINELKDKHDK-YEEIKNRYKSLKLEDLDSKRTSWLNALAVISLI 580

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1476 eDLNKVRTEKETIQKDL---------------------DAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETS 1534
Cdd:PRK01156  581 -DIETNRSRSNEIKKQLndlesrlqeieigfpddksyiDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQI 659

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 119611609 1535 AQSSGDHQEQhvsvqemQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTT 1612
Cdd:PRK01156  660 AEIDSIIPDL-------KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1318-1720 1.44e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 54.03  E-value: 1.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1318 NAEREKVQVTAKTMAQHEEL-----MKKTETMNVVMETNKMLREEKERLeqdlQQMQAKVRKLELDILPLQEANAELSEK 1392
Cdd:pfam01576   43 NALQEQLQAETELCAEAEEMrarlaARKQELEEILHELESRLEEEEERS----QQLQNEKKKMQQHIQDLEEQLDEEEAA 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1393 SGMLQAEKKLLEEDVKRWKARNQHLVSQQKdpdteeyrKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQ 1472
Cdd:pfam01576  119 RQKLQLEKVTTEAKIKKLEEDILLLEDQNS--------KLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMIS 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1473 SLKEDLN---KVRTEKETIQKDLDAKIIDIQEKVKTI-TQVKKIGRRYKTQYEELKAQQDKVMETSAQSSG---DHQEQH 1545
Cdd:pfam01576  191 DLEERLKkeeKGRQELEKAKRKLEGESTDLQEQIAELqAQIAELRAQLAKKEEELQAALARLEEETAQKNNalkKIRELE 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1546 VSVQEMQELKET----LNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT----TQEEQL 1617
Cdd:pfam01576  271 AQISELQEDLESeraaRNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEM 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1618 RQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvritalksqyEGRISRLERELREHQE 1697
Cdd:pfam01576  351 RQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDS-----------EHKRKKLEGQLQELQA 419

                          410       420
                   ....*....|....*....|...
gi 119611609  1698 RHLEQRDEPQEPSNKVPEQQRQI 1720
Cdd:pfam01576  420 RLSESERQRAELAEKLSKLQSEL 442
PRK11281 PRK11281
mechanosensitive channel MscK;
819-1138 1.55e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 53.76  E-value: 1.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  819 ERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKE------KEMLKLSEVRLSQQRESLLAEQ-------- 884
Cdd:PRK11281   66 EQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDndeetrETLSTLSLRQLESRLAQTLDQLqnaqndla 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  885 --------------RGQNLLLTNLQTIQGI---LERSETETKQRLSSQIEKLEHEISHLKKKLENeveQRHTLTRNLDVQ 947
Cdd:PRK11281  146 eynsqlvslqtqpeRAQAALYANSQRLQQIrnlLKGGKVGGKALRPSQRVLLQAEQALLNAQNDL---QRKSLEGNTQLQ 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  948 LLDTKrQLDtETNLHLNtkellkNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQ------------ 1015
Cdd:PRK11281  223 DLLQK-QRD-YLTARIQ------RLEHQLQLLQEAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQeleinlqlsqrl 294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1016 LRQTEE---------QVNDLKERLKTSTSNV-EQYQAMVTSLEES--LNKEKQ------VTEEVRKNI-EVRLK--ESAE 1074
Cdd:PRK11281  295 LKATEKlntltqqnlRVKNWLDRLTQSERNIkEQISVLKGSLLLSriLYQQQQalpsadLIEGLADRIaDLRLEqfEINQ 374

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1075 FQTQLE------KKLMevEKEKQELQDDKRRAIESM----EQQLSELKKTLSSVQNEV------QEALQRASTALSN--E 1136
Cdd:PRK11281  375 QRDALFqpdayiDKLE--AGHKSEVTDEVRDALLQLlderRELLDQLNKQLNNQLNLAinlqlnQQQLLSVSDSLQStlT 452


                  ..
gi 119611609 1137 QQ 1138
Cdd:PRK11281  453 QQ 454
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
483-940 1.72e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.62  E-value: 1.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  483 QLLLEKLENK---------RINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQ 553
Cdd:COG4717    45 AMLLERLEKEadelfkpqgRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  554 SSVLERDNRRMEI--QVKDLSQQIRVLLMELEEargnhvirdeevssadissssevISQHLVSYRNIEELQQQNQRLLVA 631
Cdd:COG4717   125 LQLLPLYQELEALeaELAELPERLEELEERLEE-----------------------LRELEEELEELEAELAELQEELEE 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  632 LRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQ----------RDMYRILLSQTTGVAI 701
Cdd:COG4717   182 LLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEleaaaleerlKEARLLLLIAAALLAL 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  702 PLHASSLDDVSLASTPKR------PSTSQTVSTPAPVPVIESTEAIEAKAALKQL-QEIFENYKKEKAENEKIQNEQLEK 774
Cdd:COG4717   262 LGLGGSLLSLILTIAGVLflvlglLALLFLLLAREKASLGKEAEELQALPALEELeEEELEELLAALGLPPDLSPEELLE 341

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  775 LQEQVTDLRSQNTKIST------QLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEK 848
Cdd:COG4717   342 LLDRIEELQELLREAEEleeelqLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  849 LAVAEvrAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnLQTIQGILERSETETkqrlssQIEKLEHEISHLKK 928
Cdd:COG4717   422 LEALD--EEELEEELEELEEELEELEEELEELREE----------LAELEAELEQLEEDG------ELAELLQELEELKA 483

                         490
                  ....*....|..
gi 119611609  929 KLENEVEQRHTL 940
Cdd:COG4717   484 ELRELAEEWAAL 495
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1476-1666 1.81e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1476 EDLNKVRTEKETIQKDLDAkiIDIQEKVKTITQVKKIGRRY---KTQYEELKAQQDKVMETSAQSSGDHQEQHvsvQEMQ 1552
Cdd:COG4913   252 ELLEPIRELAERYAAARER--LAELEYLRAALRLWFAQRRLellEAELEELRAELARLEAELERLEARLDALR---EELD 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1553 ELKETLNQAETKSK-SLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKA 1631
Cdd:COG4913   327 ELEAQIRGNGGDRLeQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEA 406

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 119611609 1632 IVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQ 1666
Cdd:COG4913   407 LAEAEAALRDLRRELRELEAEIASLERRKSNIPAR 441
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1349-1640 1.93e-06

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 52.22  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1349 ETNKMLREEKERLEQDLQQMQAKVRKLELDilpLQEANAELSEksgmLQAEKKLLEEDVKRWKARNQHLVsQQKDPDTEE 1428
Cdd:COG1340     1 SKTDELSSSLEELEEKIEELREEIEELKEK---RDELNEELKE----LAEKRDELNAQVKELREEAQELR-EKRDELNEK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1429 YRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASltnnqnliqslKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQ 1508
Cdd:COG1340    73 VKELKEERDELNEKLNELREELDELRKELAELNKA-----------GGSIDKLRKEIERLEWRQQTEVLSPEEEKELVEK 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1509 VKKIGRRYKTQYEELKaQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKtlseketEARN 1588
Cdd:COG1340   142 IKELEKELEKAKKALE-KNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRK-------EADE 213

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 119611609 1589 LQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIA 1640
Cdd:COG1340   214 LHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL 265
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1542-1689 2.36e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 2.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1542 QEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEA---------RNLQEQTVQLQSELSRLRQDLQDRTT 1612
Cdd:COG3206   212 EEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALpellqspviQQLRAQLAELEAELAELSARYTPNHP 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1613 QEEQLRQQI----TEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDV---RITALKSQYEGRI 1685
Cdd:COG3206   292 DVIALRAQIaalrAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRlerEVEVARELYESLL 371


                  ....
gi 119611609 1686 SRLE 1689
Cdd:COG3206   372 QRLE 375
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 115-596 2.53e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.19  E-value: 2.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   115 LKGRHEKFKVESEQQYFEI---EKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTR 191
Cdd:pfam05483  217 LKEDHEKIQHLEEEYKKEIndkEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   192 TKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNE----KLKESNTTKGELQLKLDELQASDVSVKAKKRLEQEK-ELLH 266
Cdd:pfam05483  297 ELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEekeaQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRlEKNE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   267 SQNTWLNTELKTKTDELLALGREKGNEILELK----------------------------------CNLENKKEEVSRLE 312
Cdd:pfam05483  377 DQLKIITMELQKKSSELEEMTKFKNNKEVELEelkkilaedeklldekkqfekiaeelkgkeqeliFLLQAREKEIHDLE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   313 EQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQAsmeekfhnELNAHIKLSNLyksaaddseaksneltraveELHKLLKEA 392
Cdd:pfam05483  457 IQLTAIKTSEEHYLKEVEDLKTELEKEKLKNI--------ELTAHCDKLLL--------------------ENKELTQEA 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   393 GEANKAIQDHLLEVEQSKDQmEKEMLEKIGRLEKELENANDLLSATkRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTE 472
Cdd:pfam05483  509 SDMTLELKKHQEDIINCKKQ-EERMLKQIENLEEKEMNLRDELESV-REEFIQKGDEVKCKLDKSEENARSIEYEVLKKE 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   473 LYNAYVETQDQLLLEKLENKriNKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQedtdkank 552
Cdd:pfam05483  587 KQMKILENKCNNLKKQIENK--NKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEII-------- 656

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 119611609   553 qssvlerDNRRMEIQVKDLSQQirVLLMELEEARgnhVIRDEEV 596
Cdd:pfam05483  657 -------DNYQKEIEDKKISEE--KLLEEVEKAK---AIADEAV 688
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 88-349 2.74e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    88 TELNKLPKSVQNkLEKFLADQQSEIDGLKGR----------HEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLE 157
Cdd:TIGR04523  419 QEKELLEKEIER-LKETIIKNNSEIKDLTNQdsvkeliiknLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   158 LEKLNNQLKALTEKNKELEiaqdrniAIQSQFTRTKEELEAEKRdlirtneRLSQELEYLTEDVKRLNEKLKesnttKGE 237
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLT-------KKISSLKEKIEKLESEKK-------EKESKISDLEDELNKDDFELK-----KEN 558

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   238 LQLKLDELQasdvsvKAKKRLEQEKELLHSQNTWLNTELKTKTDELLALGRE---KGNEILELKCNLENKKEEVSRLEEQ 314
Cdd:TIGR04523  559 LEKEIDEKN------KEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEieeKEKKISSLEKELEKAKKENEKLSSI 632

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 119611609   315 MNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK 349
Cdd:TIGR04523  633 IKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKK 667
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 485-1405 2.96e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.05  E-value: 2.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   485 LLEKLENKRINkyLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQrlqedtdKANKQSSVLERDNRRM 564
Cdd:pfam02463  178 LIEETENLAEL--IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYL-------KLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   565 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISqhlvsyrniEELQQQNQRLLVALRElgetrereeq 644
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK---------EEEELKSELLKLERRK---------- 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   645 ETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRdmyrillsqttgvaiplhasslddvslastpkrpstsq 724
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR-------------------------------------- 351

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   725 tvstpapvpvIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLq 804
Cdd:pfam02463  352 ----------EAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDL- 420

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   805 dnvegyrreitslhernQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQ 884
Cdd:pfam02463  421 -----------------LKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   885 RGQNLLLT----NLQTIQGILERSETETKQRLSSQIEKLEH-EISHLKKKLENEVE-QRHTLTRNLDVQLLDTKRQLDTE 958
Cdd:pfam02463  484 EQLELLLSrqklEERSQKESKARSGLKVLLALIKDGVGGRIiSAHGRLGDLGVAVEnYKVAISTAVIVEVSATADEVEER 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   959 TNLHLNTKELLKNAQKEIaTLKQHLSNMEVQVASQSSQRTgkgQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVE 1038
Cdd:pfam02463  564 QKLVRALTELPLGARKLR-LLIPKLKLPLKSIAVLEIDPI---LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKE 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1039 QYQAMVTSLEESLNKEKQVTEEVRKNIEVRL--KESAEFQTQLEKKLMEVEKEKQELQDDKrraIESMEQQLSELKKTLS 1116
Cdd:pfam02463  640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSEltKELLEIQELQEKAESELAKEEILRRQLE---IKKKEQREKEELKKLK 716

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1117 SVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELmlhaadVEALQAAKEQVSKMASVRQhLEETTQKAE 1196
Cdd:pfam02463  717 LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEE------KEEEKSELSLKEKELAEER-EKTEKLKVE 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1197 SQLLECKASWEERERMLKDEVSKCVCRCE-DLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEIL 1275
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEeEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1276 RfIRREKEIAETRFEVAQVESLRYRqRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLR 1355
Cdd:pfam02463  870 Q-ELLLKEEELEEQKLKDELESKEE-KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|
gi 119611609  1356 EEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEE 1405
Cdd:pfam02463  948 KEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEK 997
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 100-427 3.44e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.76  E-value: 3.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   100 KLEKFLADQQSEIDGLKGR-HEKFKV--ESEQQYFEIEKRLSHSQERLvnetrecQSLRLELEKLNNQLKALTEKNKELE 176
Cdd:TIGR02169  685 GLKRELSSLQSELRRIENRlDELSQElsDASRKIGEIEKEIEQLEQEE-------EKLKERLEELEEDLSSLEQEIENVK 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   177 IAQDRNIAIQSQFTRTKEELEAEKRDLirtnerlsqELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKK 256
Cdd:TIGR02169  758 SELKELEARIEELEEDLHKLEEALNDL---------EARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   257 R-LEQEKELLHSQNTWLNTELKTKTDELLALGREKGneilELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 335
Cdd:TIGR02169  829 EyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE----ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   336 LKEAKEqQASMEEKFHNELNAHI-----KLSNLYKSAADDSEAKSNELTraVEELHKLLKEAGEA--------NKAIQDH 402
Cdd:TIGR02169  905 IEELEA-QIEKKRKRLSELKAKLealeeELSEIEDPKGEDEEIPEEELS--LEDVQAELQRVEEEiralepvnMLAIQEY 981

                          330       340       350
                   ....*....|....*....|....*....|....
gi 119611609   403 ------LLEVEQSKDQMEKE---MLEKIGRLEKE 427
Cdd:TIGR02169  982 eevlkrLDELKEKRAKLEEErkaILERIEEYEKK 1015
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1550-1716 3.71e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 50.69  E-value: 3.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1550 EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKeeKTR 1629
Cdd:COG1579    11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNV--RNN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1630 KAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQEP 1709
Cdd:COG1579    89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168


                  ....*..
gi 119611609 1710 SNKVPEQ 1716
Cdd:COG1579   169 AAKIPPE 175
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 748-1639 4.03e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 52.75  E-value: 4.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   748 KQLQEIFENYK-KEKAENEKI-----QNEQLEKLQEQVTDLRSQ-NTKIS---TQLDFASKRYEMLQDNVEGYR------ 811
Cdd:TIGR01612  751 KDLNKILEDFKnKEKELSNKIndyakEKDELNKYKSKISEIKNHyNDQINidnIKDEDAKQNYDKSKEYIKTISikedei 830

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   812 -REITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLA------VAEVRAENLKKEKEMLKLSEVRLSQQRESLlaEQ 884
Cdd:TIGR01612  831 fKIINEMKFMKDDFLNKVDKFINFENNCKEKIDSEHEQFAeltnkiKAEISDDKLNDYEKKFNDSKSLINEINKSI--EE 908

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   885 RGQNLllTNLQTIQGILE--RSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTE-TNL 961
Cdd:TIGR01612  909 EYQNI--NTLKKVDEYIKicENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAfKDA 986

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   962 HLNTKELLKNAqkeiatLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNV-EQY 1040
Cdd:TIGR01612  987 SLNDYEAKNNE------LIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIiDEI 1060

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1041 QAMVTSLEESLNKEkqVTEEVRKNIEV--RLKESAE---FQTQLEKKLMEVEKEKQELQDDkrraIESMEQQ-------L 1108
Cdd:TIGR01612 1061 EKEIGKNIELLNKE--ILEEAEINITNfnEIKEKLKhynFDDFGKEENIKYADEINKIKDD----IKNLDQKidhhikaL 1134

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1109 SELKKTLSSVQNEVQEALQR----ASTALSNEQQARRDCQEQAKIAVEAQNKY----ERELMLHAADVEALQAAKEQVSK 1180
Cdd:TIGR01612 1135 EEIKKKSENYIDEIKAQINDledvADKAISNDDPEEIEKKIENIVTKIDKKKNiydeIKKLLNEIAEIEKDKTSLEEVKG 1214

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1181 M-ASVRQHL--------EETTQKAESQLLECKASWEERERMLKD--EVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASV 1249
Cdd:TIGR01612 1215 InLSYGKNLgklflekiDEEKKKSEHMIKAMEAYIEDLDEIKEKspEIENEMGIEMDIKAEMETFNISHDDDKDHHIISK 1294

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1250 KEgvqgplNVSLSEegkSQEQILEILRFIRREKEIAETRFEVAQ--VESLRYRQRVELLERELQELQDSLNAER-----E 1322
Cdd:TIGR01612 1295 KH------DENISD---IREKSLKIIEDFSEESDINDIKKELQKnlLDAQKHNSDINLYLNEIANIYNILKLNKikkiiD 1365

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1323 KVQVTAKTMAQHEELMK----KTETMNVVMETNKMLREEKERLE-----QDLQQMQAKVRKLELDILPLQEANAELSEKS 1393
Cdd:TIGR01612 1366 EVKEYTKEIEENNKNIKdeldKSEKLIKKIKDDINLEECKSKIEstlddKDIDECIKKIKELKNHILSEESNIDTYFKNA 1445

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1394 GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSE-------------------------KEVHTKRIQQLTE 1448
Cdd:TIGR01612 1446 DENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHDFNINElkehidkskgckdeadknakaieknKELFEQYKKDVTE 1525

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1449 EIGRLKAEIARSNASLTNNQN--LIQSLKEDLNKVRTEKETIQ---KDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEEL 1523
Cdd:TIGR01612 1526 LLNKYSALAIKNKFAKTKKDSeiIIKEIKDAHKKFILEAEKSEqkiKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENF 1605

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1524 KAQQDKVMETSAQSSGDHQEQHVSVQEMQELkeTLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQL---QSEL 1600
Cdd:TIGR01612 1606 ENKFLKISDIKKKINDCLKETESIEKKISSF--SIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELdelDSEI 1683

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|
gi 119611609  1601 SRLRQDL-QDRTTQEEQLRQQITEKEEKTRKAIVAAKSKI 1639
Cdd:TIGR01612 1684 EKIEIDVdQHKKNYEIGIIEKIKEIAIANKEEIESIKELI 1723
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
799-1412 4.06e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 4.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  799 RYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRE 878
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  879 SLLAEQRGQNLLLTNLqtiqgileRSETETKQRLSSQIEKLEHEISHLKKKLE--NEVEQRHTLTRNLdvqlldtkrqld 956
Cdd:PRK03918  239 EIEELEKELESLEGSK--------RKLEEKIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKL------------ 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  957 teTNLHLNTKELLKNAQKEIATLKQHLSNMEVQVasqssqrtgkgqpsnkEDVDDLVSQLRQTEEQVNDLKERLKTSTSN 1036
Cdd:PRK03918  299 --SEFYEEYLDELREIEKRLSRLEEEINGIEERI----------------KELEEKEERLEELKKKLKELEKRLEELEER 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1037 VEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQ------ 1107
Cdd:PRK03918  361 HELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKeikELKKAIEELKKAkgkcpv 440

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1108 -------------LSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVE---AQNKYERELMLHAADVEAL 1171
Cdd:PRK03918  441 cgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLkelAEQLKELEEKLKKYNLEEL 520

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1172 QAAKEQVSKmasvrqhLEETTQKAESQLLECKASWeERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKE 1251
Cdd:PRK03918  521 EKKAEEYEK-------LKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1252 gvqgplnvSLSEEGKSQEQILEiLRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVtaktm 1331
Cdd:PRK03918  593 --------RLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE----- 658

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1332 aqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELsEKSGMLQAEKKLLEEDVKRWK 1411
Cdd:PRK03918  659 ---EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL-EKLEKALERVEELREKVKKYK 734


                  .
gi 119611609 1412 A 1412
Cdd:PRK03918  735 A 735
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1088-1708 4.25e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 52.42  E-value: 4.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1088 KEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDC---QEQAKIAVEAQNKYERElmlh 1164
Cdd:pfam05483  102 KQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCnllKETCARSAEKTKKYEYE---- 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1165 aaDVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKlsdk 1244
Cdd:pfam05483  178 --REETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITE---- 251

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1245 vvasvkegvqgplnvslseegksQEQILEILRFIrrekeIAETRFEVAQVESLRYRQrvELLERELQELQDSLNAEREKV 1324
Cdd:pfam05483  252 -----------------------KENKMKDLTFL-----LEESRDKANQLEEKTKLQ--DENLKELIEKKDHLTKELEDI 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1325 QVTAKTMAQHEELMKktETMNVVMETNKMLREEKErleqdlQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE 1404
Cdd:pfam05483  302 KMSLQRSMSTQKALE--EDLQIATKTICQLTEEKE------AQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLE 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1405 EDVKRWKARNQHLvsQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTE 1484
Cdd:pfam05483  374 KNEDQLKIITMEL--QKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKE 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1485 KETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSgdhQEQHVSVQEMQELKETLNQAETK 1564
Cdd:pfam05483  452 IHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELT---QEASDMTLELKKHQEDIINCKKQ 528

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1565 SKSLESQVENLQktlsEKETEARNLQEQtvqLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAG 1644
Cdd:pfam05483  529 EERMLKQIENLE----EKEMNLRDELES---VREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119611609  1645 VKDQLTKENEELKQRNGALDQQKDELDVRITAlksqYEGRISRLERELREHQERHLEQRDEPQE 1708
Cdd:pfam05483  602 QIENKNKNIEELHQENKALKKKGSAENKQLNA----YEIKVNKLELELASAKQKFEEIIDNYQK 661
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
186-586 4.26e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 4.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  186 QSQFTRTKEELEA-EKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDE----LQASDVSVKAKKRLEQ 260
Cdd:PRK02224  186 RGSLDQLKAQIEEkEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEheerREELETLEAEIEDLRE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  261 EKELLHSQNTWLNTELKTKTDELLALGREKGN-------------EILELKCNLENKKEEV-SRLEEQMNGLKTSN---E 323
Cdd:PRK02224  266 TIAETEREREELAEEVRDLRERLEELEEERDDllaeaglddadaeAVEARREELEDRDEELrDRLEECRVAAQAHNeeaE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  324 HLQKHVEDLLTKLKEAKEQQASMEEKFHNElnahiklsnlyKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHL 403
Cdd:PRK02224  346 SLREDADDLEERAEELREEAAELESELEEA-----------REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFL 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  404 LEVEQSKD---QMEKEMLEKIGRLEKELENANDLLSATK--------------------RKGAILSEEELAAMSPTAAAV 460
Cdd:PRK02224  415 EELREERDelrEREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedRERVEELEAELEDLEEEVEEV 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  461 AKIVKPGMKLtelynayVETQDQllLEKLENKRinkylDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEI 540
Cdd:PRK02224  495 EERLERAEDL-------VEAEDR--IERLEERR-----EDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 119611609  541 QRLQEDTDKANKQSSVLERDNRRMEIQVKDLsQQIRVLLMELEEAR 586
Cdd:PRK02224  561 AEAEEEAEEAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAE 605
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 737-945 7.78e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 7.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  737 STEAIEAKAALKQLQEIFENYKKEKAENEKIQNE---QLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRRE 813
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKAllkQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  814 ITSLHERNQKLTATTQKQEQIINTM----TQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNL 889
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 119611609  890 LLTNLQTIQGILERSETETKQRLSsqieKLEHEISHLKKKLENEVEQRHTLTRNLD 945
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLA----RLEKELAELAAELAELQQEAEELEALIA 230
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
894-1374 9.85e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 9.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  894 LQTIQGILERSET--ETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDvQLLDTKRQLDTETNLHLNTKELLKN 971
Cdd:PRK02224  236 RDEADEVLEEHEErrEELETLEAEIEDLRETIAETEREREELAEEVRDLRERLE-ELEEERDDLLAEAGLDDADAEAVEA 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  972 AQKEIATLKQHLSNmEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLE--- 1048
Cdd:PRK02224  315 RREELEDRDEELRD-RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEeei 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1049 ESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRA------------------------IESM 1104
Cdd:PRK02224  394 EELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAealleagkcpecgqpvegsphvetIEED 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1105 EQQLSELKKTLSSV---QNEVQEALQRASTALSNEQQARRdCQEQAKIAVEAQNKYERELmlhAADVEALQAAKEQVSKM 1181
Cdd:PRK02224  474 RERVEELEAELEDLeeeVEEVEERLERAEDLVEAEDRIER-LEERREDLEELIAERRETI---EEKRERAEELRERAAEL 549

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1182 ASVRQHLEETTQKAESQLLECKasweERERMLKDEVSKCVCRCEDLEKQNRLLhDQIEKLSDKVvasvkegvqGPLNVSL 1261
Cdd:PRK02224  550 EAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAELKERIESLERIRTLL-AAIADAEDEI---------ERLREKR 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1262 SEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRY-RQRVELLERELQELQDSLNAEREKVQVTA----KTMAQHEE 1336
Cdd:PRK02224  616 EALAELNDERRERLAEKRERKRELEAEFDEARIEEAREdKERAEEYLEQVEEKLDELREERDDLQAEIgaveNELEELEE 695

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 119611609 1337 LMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRK 1374
Cdd:PRK02224  696 LRERREALENRVEALEALYDEAEELESMYGDLRAELRQ 733
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 741-1213 1.04e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 50.98  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   741 IEAKAALKQLQEIFENYKKEkaeNEKIQNEQLEKLQeqVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLheR 820
Cdd:pfam10174  188 AEAEMQLGHLEVLLDQKEKE---NIHLREELHRRNQ--LQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQML--K 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   821 NQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLS---EVRLSQQ----------RESLLAEQRGQ 887
Cdd:pfam10174  261 TNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQtklETLTNQNsdckqhievlKESLTAKEQRA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   888 NLLLTNLQTIQGILERSE------TETKQRLSSQIEKLEHEISHLKKKL---ENEVEQRHTLTRNLDVQLLDTKRQLDTE 958
Cdd:pfam10174  341 AILQTEVDALRLRLEEKEsflnkkTKQLQDLTEEKSTLAGEIRDLKDMLdvkERKINVLQKKIENLQEQLRDKDKQLAGL 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   959 TNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQpSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVE 1038
Cdd:pfam10174  421 KERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDR-ERLEELESLKKENKDLKEKVSALQPELTEKESSLI 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1039 QYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEK--KLMEVEKEKQELQDdkrrAIESMEQQLSELKKTLS 1116
Cdd:pfam10174  500 DLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKahNAEEAVRTNPEIND----RIRLLEQEVARYKEESG 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1117 SVQNEVQ---EALQRASTALSN--------EQQARRDCQEQAKIAV-------EAQNKYERELMLH------AADVEALQ 1172
Cdd:pfam10174  576 KAQAEVErllGILREVENEKNDkdkkiaelESLTLRQMKEQNKKVAnikhgqqEMKKKGAQLLEEArrrednLADNSQQL 655

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 119611609  1173 AAKEQVSKMASVRQHLEETTQKAESQllecKASWEERERML 1213
Cdd:pfam10174  656 QLEELMGALEKTRQELDATKARLSST----QQSLAEKDGHL 692
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 146-445 1.11e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   146 NETRECQSLRLELEKLnnqlkALTEKNKELEIAQDRNIAIQSQFtrtkEELEAEKRDLIRTNERLSQELEYLTEDVKRLN 225
Cdd:TIGR02169  208 EKAERYQALLKEKREY-----EGYELLKEKEALERQKEAIERQL----ASLEEELEKLTEEISELEKRLEEIEQLLEELN 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   226 EKLKE-SNTTKGELQLKLDELQASDVSVKAKKRlEQEKELLHSQNTWLNTElktktdellALGREKGNEILELKCNLENK 304
Cdd:TIGR02169  279 KKIKDlGEEEQLRVKEKIGELEAEIASLERSIA-EKERELEDAEERLAKLE---------AEIDKLLAEIEELEREIEEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   305 KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF------HNELNAHI-KLSNLYKSAADDSEAKSNE 377
Cdd:TIGR02169  349 RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLeklkreINELKRELdRLQEELQRLSEELADLNAA 428

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 119611609   378 LTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENANDLLSATKRKGAIL 445
Cdd:TIGR02169  429 IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE-QELYDLKEEYDRVEKELSKLQRELAEA 495
46 PHA02562
endonuclease subunit; Provisional
 1388-1610 1.26e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.40  E-value: 1.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1388 ELSEKSGMLQAEKKLLEEDVKrwkARNQHLVSQQKDPDTEEYRKllsekevhTKRIQQLTEEIGRLKAEIARSNASLTNN 1467
Cdd:PHA02562  178 ELNQQIQTLDMKIDHIQQQIK---TYNKNIEEQRKKNGENIARK--------QNKYDELVEEAKTIKAEIEELTDELLNL 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1468 QNLIQSLKEDLNKVRTEKETIQKDLD--AKII--------------DIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVM 1531
Cdd:PHA02562  247 VMDIEDPSAALNKLNTAAAKIKSKIEqfQKVIkmyekggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELE 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1532 ETSAQssgdHQEQHVSVQEMQELKETLNQA----ETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDL 1607
Cdd:PHA02562  327 EIMDE----FNEQSKKLLELKNKISTNKQSlitlVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEK 402


                  ...
gi 119611609 1608 QDR 1610
Cdd:PHA02562  403 YHR 405
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
900-1466 1.42e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  900 ILERSETETK-QRLSSQIEKLE--HEIshlkkkLENEVEQRHTLTR--------NLDVQLLDTKRQLDTETNLHLNTKEL 968
Cdd:COG4913   217 MLEEPDTFEAaDALVEHFDDLEraHEA------LEDAREQIELLEPirelaeryAAARERLAELEYLRAALRLWFAQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  969 LKnAQKEIATLKQHLSNMEVQVASQSSQRTgkgqpSNKEDVDDLVSQLRQT--------EEQVNDLKERLKTSTSNVEQY 1040
Cdd:COG4913   291 EL-LEAELEELRAELARLEAELERLEARLD-----ALREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARL 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1041 QAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAiesmEQQLSELKKTLSSVQN 1120
Cdd:COG4913   365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL----EAEIASLERRKSNIPA 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1121 EVQEALQRASTALSNEqqarrdcQEQAKIA---VEAQNKYER-----ELMLHAA------DVEALQAAKEQVSKMaSVRQ 1186
Cdd:COG4913   441 RLLALRDALAEALGLD-------EAELPFVgelIEVRPEEERwrgaiERVLGGFaltllvPPEHYAAALRWVNRL-HLRG 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1187 HL----------EETTQKAESQLLECKASWEERE--RMLKDEVSKC---VCrCEDLE---------------KQNRLLH- 1235
Cdd:COG4913   513 RLvyervrtglpDPERPRLDPDSLAGKLDFKPHPfrAWLEAELGRRfdyVC-VDSPEelrrhpraitragqvKGNGTRHe 591

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1236 --DQIEKLSDKVVasvkegvqgplnvslseeGKSQEQILEILrfirrEKEIAETRFEVAQVESLryRQRVELLERELQEL 1313
Cdd:COG4913   592 kdDRRRIRSRYVL------------------GFDNRAKLAAL-----EAELAELEEELAEAEER--LEALEAELDALQER 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1314 QDSLNAEREKVQVTAKTMAQHEELMKktetmnvvmetnkmLREEKERLEQ---DLQQMQAKVRKLELDILPLQEANAELS 1390
Cdd:COG4913   647 REALQRLAEYSWDEIDVASAEREIAE--------------LEAELERLDAssdDLAALEEQLEELEAELEELEEELDELK 712

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609 1391 EKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDT---EEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1466
Cdd:COG4913   713 GEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRallEERFAAALGDAVERELRENLEERIDALRARLNRAEEELER 791
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1440-1705 1.89e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1440 TKRIQQLTEEIGRLKAEIARSNASltnnqnlIQSLKEDLNKVRTEKETIQK--DLDAKIIDIQEKVKTITQVKKigrryk 1517
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEER-------LEALEAELDALQERREALQRlaEYSWDEIDVASAEREIAELEA------ 675

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1518 tQYEELKAQQDKVMETSAQSSGdhqeqhvSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQ 1597
Cdd:COG4913   676 -ELERLDASSDDLAALEEQLEE-------LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL 747

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1598 SEL--SRLRQDLQDRttQEEQLRQQITEKEEKTRKAIVAAKSKIAhlagvkDQLTKENEELKQRNGALDQQKDELDvrit 1675
Cdd:COG4913   748 RALleERFAAALGDA--VERELRENLEERIDALRARLNRAEEELE------RAMRAFNREWPAETADLDADLESLP---- 815

                         250       260       270
                  ....*....|....*....|....*....|.
gi 119611609 1676 alksQYEGRISRLERE-LREHQERHLEQRDE 1705
Cdd:COG4913   816 ----EYLALLDRLEEDgLPEYEERFKELLNE 842
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
194-670 1.89e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  194 EELEAEKRDLIRTNERLSqelEYLTEDVKRLNEKLKESNTTKGELQLKLDELQasdvsvkakkRLEQEKELLHSQNTWLN 273
Cdd:COG4717    49 ERLEKEADELFKPQGRKP---ELNLKELKELEEELKEAEEKEEEYAELQEELE----------ELEEELEELEAELEELR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  274 TELKTktdellalgrekgneiLELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKfHNE 353
Cdd:COG4717   116 EELEK----------------LEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAEL-QEE 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  354 LNAHIKLSNLYKsaaddsEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENAND 433
Cdd:COG4717   179 LEELLEQLSLAT------EEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL-EAAALEERLKEARLL 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  434 LLSATKRKGAILSEEELAAMSPTAAAVAKIV---------KPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKE 504
Cdd:COG4717   252 LLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLP 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  505 VEAKAPILKRQREEYERAQKAVASLSVKLEQAmkEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEE 584
Cdd:COG4717   332 PDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEE 409

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  585 ARGNHvirDEEVSSADISSSSEVISQHLVSYRniEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTE 664
Cdd:COG4717   410 QLEEL---LGELEELLEALDEEELEEELEELE--EELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAE 484


                  ....*.
gi 119611609  665 LEQLRK 670
Cdd:COG4717   485 LRELAE 490
PTZ00121 PTZ00121
MAEBL; Provisional
 194-1071 2.17e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  194 EELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAK--KRLEQEKELLHSQNTw 271
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEdaKKAEAARKAEEVRKA- 1190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  272 lnTELKTKTDELLALGREKGNEilelkcnlENKKEEVSRLEEQMNGLKTsnehlqKHVEDLLTKLKEAKEQqasmEEKFH 351
Cdd:PTZ00121 1191 --EELRKAEDARKAEAARKAEE--------ERKAEEARKAEDAKKAEAV------KKAEEAKKDAEEAKKA----EEERN 1250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  352 NELNAHIKLSNLYKSAADDSEAKSNElTRAVEELHKL--LKEAGEANKAiqDHLLEVEQSKDQMEKEmlEKIGRLEKELE 429
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAAIKAEE-ARKADELKKAeeKKKADEAKKA--EEKKKADEAKKKAEEA--KKADEAKKKAE 1325

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  430 NANDLLSATKRKG--AILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEA 507
Cdd:PTZ00121 1326 EAKKKADAAKKKAeeAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  508 KAPILKRQREEYERAQ--KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEA 585
Cdd:PTZ00121 1406 KADELKKAAAAKKKADeaKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA 1485

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  586 RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQrllvaLRELGETREREEQETTSSKITELQLKLESALTEL 665
Cdd:PTZ00121 1486 DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADE-----AKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  666 EQLRKSRQhqmqlvdsiVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQtvstpapvpviESTEAIEAKA 745
Cdd:PTZ00121 1561 EEKKKAEE---------AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE-----------EAKKAEEAKI 1620

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  746 ALKQLQEIFENYK-----KEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQldfASKRYEMLQDNVEGYRREitslHER 820
Cdd:PTZ00121 1621 KAEELKKAEEEKKkveqlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE---DKKKAEEAKKAEEDEKKA----AEA 1693

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  821 NQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVR---AENLKKEKEMLKLSEVRLSQQRESllaEQRGQNLLLTNLQTI 897
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENkikAEEAKKEAEEDKKKAEEAKKDEEE---KKKIAHLKKEEEKKA 1770

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  898 QGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIA 977
Cdd:PTZ00121 1771 EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFE 1850

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  978 TLKQHLSNMEVQvaSQSSQRTGKGQPSNKEDVDDLVSQLRQTEE-QVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQ 1056
Cdd:PTZ00121 1851 KHKFNKNNENGE--DGNKEADFNKEKDLKEDDEEEIEEADEIEKiDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRD 1928

                         890
                  ....*....|....*
gi 119611609 1057 VTEEVRKNIEVRLKE 1071
Cdd:PTZ00121 1929 AEETREEIIKISKKD 1943
PLN02939 PLN02939
transferase, transferring glycosyl groups
 862-1121 2.38e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.90  E-value: 2.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  862 EKEMLKLSEVRLS--QQRESLLAE----QRGQNLLLTNLqtiqgilerSETETKQRLSSQ-----------IEKLEHEIS 924
Cdd:PLN02939  141 EKNILLLNQARLQalEDLEKILTEkealQGKINILEMRL---------SETDARIKLAAQekihveileeqLEKLRNELL 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  925 HlkkKLENEVEQRHTLTRNLD------VQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQ-VASQssqr 997
Cdd:PLN02939  212 I---RGATEGLCVHSLSKELDvlkeenMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKfIVAQ---- 284

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  998 tgkgqpsnkEDVDDLVS-QLRQTEEQVNDLKERLKTSTSNVEQYqAMVTSLEESLNKEKQVTEEVRKNIEVRlKESAEFQ 1076
Cdd:PLN02939  285 ---------EDVSKLSPlQYDCWWEKVENLQDLLDRATNQVEKA-ALVLDQNQDLRDKVDKLEASLKEANVS-KFSSYKV 353

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 119611609 1077 TQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNE 1121
Cdd:PLN02939  354 ELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEE 398
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
926-1414 2.48e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 2.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  926 LKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQpsn 1005
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK--- 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1006 KEDVDDLVSQLRQTEEQVNDLKERLktstsnveqyqamvtsleESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLME 1085
Cdd:COG4717   124 LLQLLPLYQELEALEAELAELPERL------------------EELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1086 VEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVqEALQRASTALSNEQQARRDCQEQAK-----------IAVEAQ 1154
Cdd:COG4717   186 LSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL-EELEEELEQLENELEAAALEERLKEarlllliaaalLALLGL 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1155 NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERmlkdevskcvcrcEDLEKQNRLL 1234
Cdd:COG4717   265 GGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEEL-------------EELLAALGLP 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1235 HDQIEKLSDKVVASVKEGVQgplnvSLSEEGKSQEQileiLRFIRREKEIAETrFEVAQVESL-RYRQRVELLERELQEL 1313
Cdd:COG4717   332 PDLSPEELLELLDRIEELQE-----LLREAEELEEE----LQLEELEQEIAAL-LAEAGVEDEeELRAALEQAEEYQELK 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1314 QDSLNAERekvQVTAKTMAQHEELMKKTETMnvVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLqEANAELSEKS 1393
Cdd:COG4717   402 EELEELEE---QLEELLGELEELLEALDEEE--LEEELEELEEELEELEEELEELREELAELEAELEQL-EEDGELAELL 475

                         490       500
                  ....*....|....*....|.
gi 119611609 1394 GMLQAEKKLLEEDVKRWKARN 1414
Cdd:COG4717   476 QELEELKAELRELAEEWAALK 496
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1351-1715 2.76e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 2.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1351 NKMLREEKERLEQDLQQMQAKVRK--------LELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHL--VSQ 1420
Cdd:PRK02224  179 ERVLSDQRGSLDQLKAQIEEKEEKdlherlngLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELetLEA 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1421 QKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQ 1500
Cdd:PRK02224  259 EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1501 EKVKTITQVKKIGRRYKTQYEELKAQQDKVMEtsaqssgdhqeqhvsvqEMQELKETLNQAETKSKSLESQVENLQKTLS 1580
Cdd:PRK02224  339 AHNEEAESLREDADDLEERAEELREEAAELES-----------------ELEEAREAVEDRREEIEELEEEIEELRERFG 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1581 EKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEE-------KTRKAIVAAKSKIAHLAGVKDQLTKEN 1653
Cdd:PRK02224  402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcPECGQPVEGSPHVETIEEDRERVEELE 481

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119611609 1654 EELKQrngaLDQQKDELDVRITALKS--QYEGRISRLERELREHQERHLEQRDEPQEPSNKVPE 1715
Cdd:PRK02224  482 AELED----LEEEVEEVEERLERAEDlvEAEDRIERLEERREDLEELIAERRETIEEKRERAEE 541
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 125-349 2.92e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  125 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDrniAIQSQFTRTKEELEAEKRDLI 204
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA---ALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  205 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQA-SDVSVKAKKRLEQEKELLHSqntwLNTELKTKTDEL 283
Cdd:COG4942   101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAELAA----LRAELEAERAEL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119611609  284 LALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK 349
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1355-1494 3.74e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.09  E-value: 3.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1355 REEKERLEQDLQQMQAKVRKLEldilplqeanaelsEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLS 1434
Cdd:COG2433   398 EREKEHEERELTEEEEEIRRLE--------------EQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRK 463

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1435 EKEvhtkrIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDA 1494
Cdd:COG2433   464 DRE-----ISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVEK 518
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1549-1723 4.78e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 4.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1549 QEMQELKETLNQAETKskslESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQ--DLQDRTTQEEQLRQQITEKEE 1626
Cdd:COG4717    71 KELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELEELREELEKLEKllQLLPLYQELEALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1627 KTRKAivaaKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDV----RITALKSQYE---GRISRLERELREHQERH 1699
Cdd:COG4717   147 RLEEL----EERLEELRELEEELEELEAELAELQEELEELLEQLSLateeELQDLAEELEelqQRLAELEEELEEAQEEL 222

                         170       180
                  ....*....|....*....|....
gi 119611609 1700 LEQRDEPQEPSNKVPEQQRQITLK 1723
Cdd:COG4717   223 EELEEELEQLENELEAAALEERLK 246
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 746-1621 5.59e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.89  E-value: 5.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   746 ALKQLQEIFENYKKEKAENEkIQNEQLEKLQEQVTDLRSQNTKISTQLDFA---SKRYEMLQDNVEGYRREI----TSLH 818
Cdd:TIGR00606  187 ALETLRQVRQTQGQKVQEHQ-MELKYLKQYKEKACEIRDQITSKEAQLESSreiVKSYENELDPLKNRLKEIehnlSKIM 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   819 ERNQKLTA--TTQKQEQIINT-----MTQDLRGANEKL---------AVAEVRAENLKKEKEMLKLSEVR--LSQQRESL 880
Cdd:TIGR00606  266 KLDNEIKAlkSRKKQMEKDNSelelkMEKVFQGTDEQLndlyhnhqrTVREKERELVDCQRELEKLNKERrlLNQEKTEL 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   881 LAEQRGQNLLLTNLQtiQGILERSETETKQRLSSQIEKLEHEishlkKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETN 960
Cdd:TIGR00606  346 LVEQGRLQLQADRHQ--EHIRARDSLIQSLATRLELDGFERG-----PFSERQIKNFHTLVIERQEDEAKTAAQLCADLQ 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   961 LHLNTK-ELLKNAQKEIATLKQHLSNMEVQVASQSSQ-----RTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKErlktsT 1034
Cdd:TIGR00606  419 SKERLKqEQADEIRDEKKGLGRTIELKKEILEKKQEElkfviKELQQLEGSSDRILELDQELRKAERELSKAEK-----N 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1035 SNVEQYQAMVTSLE-ESLNKEKQVTEEVRKNIEvrLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQL----- 1108
Cdd:TIGR00606  494 SLTETLKKEVKSLQnEKADLDRKLRKLDQEMEQ--LNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpn 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1109 -SELKKTLSSVQNEV---QEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELM------LHAADVEALQAAKEQV 1178
Cdd:TIGR00606  572 kKQLEDWLHSKSKEInqtRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFdvcgsqDEESDLERLKEEIEKS 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1179 SK--------MASVRQHLEETTQ-------------KAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQ 1237
Cdd:TIGR00606  652 SKqramlagaTAVYSQFITQLTDenqsccpvcqrvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1238 IE------KLSDKVVASVKEGVQGpLNVSLSEEGKSQEQILEILRFIRREKEIAET-----------RFEVAQVESLRYR 1300
Cdd:TIGR00606  732 APgrqsiiDLKEKEIPELRNKLQK-VNRDIQRLKNDIEEQETLLGTIMPEEESAKVcltdvtimerfQMELKDVERKIAQ 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1301 QRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKK-----TETMNVVMETNKMLREEKERLEQDLQQMQAKVRKL 1375
Cdd:TIGR00606  811 QAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKliqdqQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQL 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1376 ELDILPLQEANAELSEKSGMLQAEKKLLEEDVKR--WKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEE---- 1449
Cdd:TIGR00606  891 VELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEkeELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDgkdd 970

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1450 -IGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETiQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKaqQD 1528
Cdd:TIGR00606  971 yLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDT-QKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMG--QM 1047

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1529 KVMETSaqssgdhQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKetEARNLQEQTVQLQSELSRLRQDLQ 1608
Cdd:TIGR00606 1048 QVLQMK-------QEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREP--QFRDAEEKYREMMIVMRTTELVNK 1118

                          970
                   ....*....|...
gi 119611609  1609 DRTTQEEQLRQQI 1621
Cdd:TIGR00606 1119 DLDIYYKTLDQAI 1131
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1566-1705 6.14e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 6.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1566 KSLESQVENLQ---KTLSEKETEARNLQEQTVQLQselsRLRQDLQDRTTQEEQLRQQiteKEEKTRKAIVAAKSKIAHL 1642
Cdd:COG4913   221 PDTFEAADALVehfDDLERAHEALEDAREQIELLE----PIRELAERYAAARERLAEL---EYLRAALRLWFAQRRLELL 293

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609 1643 AGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEG----RISRLERELREHQERHLEQRDE 1705
Cdd:COG4913   294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGnggdRLEQLEREIERLERELEERERR 360
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1076-1702 6.64e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 6.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1076 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEaLQRASTALSNEQqaRRDCQEQAKIAVEAQN 1155
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQE-MQMERDAMADIR--RRESQSQEDLRNQLQN 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1156 --------KYERELMLHAADVEALQAAKEQVSK---MASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVcrc 1224
Cdd:pfam15921  150 tvheleaaKCLKEDMLEDSNTQIEQLRKMMLSHegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIL--- 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1225 EDLEKQNRLLHDQIEKLSDKVVAsvkegvqgplnvsLSEEGKSQEQILEILRFIRREKEIAETRFEVAQveslryrqrVE 1304
Cdd:pfam15921  227 RELDTEISYLKGRIFPVEDQLEA-------------LKSESQNKIELLLQQHQDRIEQLISEHEVEITG---------LT 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1305 LLERELQELQDSLNAEREKVQVTAKTmaQHEELMKK-TETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQ 1383
Cdd:pfam15921  285 EKASSARSQANSIQSQLEIIQEQARN--QNSMYMRQlSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEAR 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1384 EANAELSEKSGMLQAE-KKLLEEDVKRWKARNQHLVSQQK--DPDT------EEYRKLLSEKEVHTKRIQQLTE------ 1448
Cdd:pfam15921  363 TERDQFSQESGNLDDQlQKLLADLHKREKELSLEKEQNKRlwDRDTgnsitiDHLRRELDDRNMEVQRLEALLKamksec 442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1449 --EIGRLKAEIARSNASLTNNQNL---IQSLKEDLNKVRTE-------KETIQKDLDAKIIDIQEKVKTI----TQVKKI 1512
Cdd:pfam15921  443 qgQMERQMAAIQGKNESLEKVSSLtaqLESTKEMLRKVVEEltakkmtLESSERTVSDLTASLQEKERAIeatnAEITKL 522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1513 GRRYKTQYEELKaqqdkvmetSAQSSGDHQeQHVSVqEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQ 1592
Cdd:pfam15921  523 RSRVDLKLQELQ---------HLKNEGDHL-RNVQT-ECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVE 591

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1593 TVQLQSELSRLRQDLQD-------RTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVK---DQLTKENEELKQRNGA 1662
Cdd:pfam15921  592 KAQLEKEINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKqerDQLLNEVKTSRNELNS 671

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 119611609  1663 LDQQKDELDVRITALKSQYEGRISRLERELREHQErHLEQ 1702
Cdd:pfam15921  672 LSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQS-ELEQ 710
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1055-1698 6.91e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.36  E-value: 6.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1055 KQVTEEVRKNI-----EVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRaIESMEQQLSELKKTLSSVQ------NEVQ 1123
Cdd:PRK01156  111 DDTTKYIEKNIlgiskDVFLNSIFVGQGEMDSLISGDPAQRKKILDEILE-INSLERNYDKLKDVIDMLRaeisniDYLE 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1124 EALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL---- 1199
Cdd:PRK01156  190 EKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLsmel 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1200 ---LECKASWEERERMLKDEVSKCVCRCEDLEKqnrlLHDQIEKLSDkvvasVKEGVQGPLNVSLSEEGKsqeqiLEILR 1276
Cdd:PRK01156  270 eknNYYKELEERHMKIINDPVYKNRNYINDYFK----YKNDIENKKQ-----ILSNIDAEINKYHAIIKK-----LSVLQ 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1277 FIRREKEIAETRFEVAQVESLRYRQRvELLERELQELQDSLNAEREKVQVTAKTMAQheelmKKTETMNVVMETNKMLRE 1356
Cdd:PRK01156  336 KDYNDYIKKKSRYDDLNNQILELEGY-EMDYNSYLKSIESLKKKIEEYSKNIERMSA-----FISEILKIQEIDPDAIKK 409

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1357 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLV---SQQKDPDTEEYRKLL 1433
Cdd:PRK01156  410 ELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIInhyNEKKSRLEEKIREIE 489

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1434 SE-KEVHTKRIQQLTEEIGRLKAEIARSNASltnnQNLIQSLKEDLNKVRTEKETIqKDLDAKIIDIQEKVKTITQvkKI 1512
Cdd:PRK01156  490 IEvKDIDEKIVDLKKRKEYLESEEINKSINE----YNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSLKL--ED 562

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1513 GRRYKTQYEELKAQQDKVMETSAQSSGDhqeqhvsvqemqELKETLNQAETKSKSLESQVENLQ----KTLSEKETEARN 1588
Cdd:PRK01156  563 LDSKRTSWLNALAVISLIDIETNRSRSN------------EIKKQLNDLESRLQEIEIGFPDDKsyidKSIREIENEANN 630

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1589 LQEQtvqlqselsrlRQDLQDRTTQEEQLRQQItekeEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKD 1668
Cdd:PRK01156  631 LNNK-----------YNEIQENKILIEKLRGKI----DNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKA 695

                         650       660       670
                  ....*....|....*....|....*....|
gi 119611609 1669 ELdVRITALKSQYEGRISRLERELREHQER 1698
Cdd:PRK01156  696 NR-ARLESTIEILRTRINELSDRINDINET 724
PRK01156 PRK01156
chromosome segregation protein; Provisional
 141-574 6.97e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.36  E-value: 6.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  141 QERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQD---RNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYL 217
Cdd:PRK01156  151 RKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEklkSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNA 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  218 TEDVKRLNEKLKESNTTKGELQLKLDELQASDvsvkAKKRLEQEKELLHSQntwLNTELKTKTDELLALGREKGNEILEL 297
Cdd:PRK01156  231 MDDYNNLKSALNELSSLEDMKNRYESEIKTAE----SDLSMELEKNNYYKE---LEERHMKIINDPVYKNRNYINDYFKY 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  298 KCNLENKKEEVSRLEEQMNGLKTSN---EHLQKHVEDLLTKLKEAKE--QQASMEEKFHNELNAHIklsNLYKSAADDSE 372
Cdd:PRK01156  304 KNDIENKKQILSNIDAEINKYHAIIkklSVLQKDYNDYIKKKSRYDDlnNQILELEGYEMDYNSYL---KSIESLKKKIE 380

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  373 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKemleKIGRLEKELENANDLLSATKRKGAILSEEELAA 452
Cdd:PRK01156  381 EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS----KVSSLNQRIRALRENLDELSRNMEMLNGQSVCP 456

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  453 MSPTAAAVAKIvkpgmklTELYNAYVETQDQLLLEKLENKRINKYLDE-IVKEVEAKAPILKRQREEYERAQKAVASLSV 531
Cdd:PRK01156  457 VCGTTLGEEKS-------NHIINHYNEKKSRLEEKIREIEIEVKDIDEkIVDLKKRKEYLESEEINKSINEYNKIESARA 529

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 119611609  532 KLEQAMKEIQRLQEDTDKANkqssvlERDNRRMEIQVKDLSQQ 574
Cdd:PRK01156  530 DLEDIKIKINELKDKHDKYE------EIKNRYKSLKLEDLDSK 566
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1159-1702 6.97e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 6.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1159 RELMLHAADV-EALQAAKEQVSKMASVRQHLEETTQKAEsQLLECKASWEERERmLKDEVSKCVcRCEDL------EKQN 1231
Cdd:COG4913   214 REYMLEEPDTfEAADALVEHFDDLERAHEALEDAREQIE-LLEPIRELAERYAA-ARERLAELE-YLRAAlrlwfaQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1232 RLLHDQIEKLSDKvvasvKEGVQGPLNVSLSEEGKSQEQILEILRFIRR---------EKEIAETRFEVAQVE--SLRYR 1300
Cdd:COG4913   291 ELLEAELEELRAE-----LARLEAELERLEARLDALREELDELEAQIRGnggdrleqlEREIERLERELEERErrRARLE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1301 QRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNkmLREEKERLEQDLQQMQAkvRKLELDiL 1380
Cdd:COG4913   366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD--LRRELRELEAEIASLER--RKSNIP-A 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1381 PLQEANAELSEKSGMLQAEKKLLEE--DVK----RWKA------RNQH---LVSQQKDPD-TEEYRKLLSEKEVHTKRIQ 1444
Cdd:COG4913   441 RLLALRDALAEALGLDEAELPFVGEliEVRpeeeRWRGaiervlGGFAltlLVPPEHYAAaLRWVNRLHLRGRLVYERVR 520

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1445 QLTEEIGRLKA---------EIARS------NASLTNNQNLIQ--SLkEDLNKVR---TEKETIQKDLDAKIIDIQEKVK 1504
Cdd:COG4913   521 TGLPDPERPRLdpdslagklDFKPHpfrawlEAELGRRFDYVCvdSP-EELRRHPraiTRAGQVKGNGTRHEKDDRRRIR 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1505 TITQvkkIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQ------AETKSKSLESQVENLQKT 1578
Cdd:COG4913   600 SRYV---LGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswDEIDVASAEREIAELEAE 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1579 LSEKET---EARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAivaaksKIAHLAGVKDQLTKENEE 1655
Cdd:COG4913   677 LERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL------QDRLEAAEDLARLELRAL 750

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 119611609 1656 LKQRNGALDQQKDELDVR--ITALKSQYEGRISRLERELREHQERHLEQ 1702
Cdd:COG4913   751 LEERFAAALGDAVERELRenLEERIDALRARLNRAEEELERAMRAFNRE 799
PRK11281 PRK11281
mechanosensitive channel MscK;
1355-1602 7.90e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 48.37  E-value: 7.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1355 REEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKS----GMLQAEKKLLE--EDVKRWKAR----NQHLVSQQKDP 1424
Cdd:PRK11281   79 KEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETlstlSLRQLESRLAQtlDQLQNAQNDlaeyNSQLVSLQTQP 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1425 dtEEYRKLLSEkevHTKRIQQLT---------------EEIGRLKAEIARSNASLTNNQNLIQSlkedlNKVRTEKETIQ 1489
Cdd:PRK11281  159 --ERAQAALYA---NSQRLQQIRnllkggkvggkalrpSQRVLLQAEQALLNAQNDLQRKSLEG-----NTQLQDLLQKQ 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1490 KDL-DAKIIDIQEKVKTITQVkkIGRRYKTQYEELKAQQDkvmetSAQSSGDHQEQHVSVQEMQ---ELKETLNQAETKS 1565
Cdd:PRK11281  229 RDYlTARIQRLEHQLQLLQEA--INSKRLTLSEKTVQEAQ-----SQDEAARIQANPLVAQELEinlQLSQRLLKATEKL 301

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 119611609 1566 KSL-------ESQVENLQKTlseketeARNLQEQTVQLQSE--LSR 1602
Cdd:PRK11281  302 NTLtqqnlrvKNWLDRLTQS-------ERNIKEQISVLKGSllLSR 340
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
742-961 8.47e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 8.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  742 EAKAALKQLQEIFENYK--KEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQ--------LDFASKRYEMLQDNVEGYR 811
Cdd:COG4913   222 DTFEAADALVEHFDDLEraHEALEDAREQIELLEPIRELAERYAAARERLAELeylraalrLWFAQRRLELLEAELEELR 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  812 REITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKlavaevRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNL-- 889
Cdd:COG4913   302 AELARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLpl 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  890 ------LLTNLQTIQGILERSETETKQ------RLSSQIEKLEHEISHLKKKLEnEVEQRHTltrNLDVQLLDTKRQLDT 957
Cdd:COG4913   376 pasaeeFAALRAEAAALLEALEEELEAleealaEAEAALRDLRRELRELEAEIA-SLERRKS---NIPARLLALRDALAE 451


                  ....
gi 119611609  958 ETNL 961
Cdd:COG4913   452 ALGL 455
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
105-292 8.98e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 8.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  105 LADQQSEIDGLKGRHEKFK-VESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdrnI 183
Cdd:COG4913   257 IRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELE------A 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  184 AIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASdvSVKAKKRLEQEKE 263
Cdd:COG4913   331 QIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEA--LEEELEALEEALA 408

                         170       180
                  ....*....|....*....|....*....
gi 119611609  264 LLHSQNTWLNTELKTKTDELLALGREKGN 292
Cdd:COG4913   409 EAEAALRDLRRELRELEAEIASLERRKSN 437
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1421-1640 9.14e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 9.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1421 QKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQ 1500
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1501 EK-------------------VKTITQVKKIGRRYKTQYEELKAQQDKVmetsaqssgdhqeqhvsVQEMQELKETLNQA 1561
Cdd:COG3883    97 RSggsvsyldvllgsesfsdfLDRLSALSKIADADADLLEELKADKAEL-----------------EAKKAELEAKLAEL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609 1562 ETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIA 1640
Cdd:COG3883   160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
99-586 9.66e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 9.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   99 NKLEKFLADQQSEIDglkgRHEKFKVESEQQYFEIEKRLSHSQERLvnetRECQSLRLELEKLNnqlKALTEKNKELEIA 178
Cdd:PRK02224  209 NGLESELAELDEEIE----RYEEQREQARETRDEADEVLEEHEERR----EELETLEAEIEDLR---ETIAETEREREEL 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  179 QDRniaIQSQfTRTKEELEAEKRDLIRT-------NERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASdvs 251
Cdd:PRK02224  278 AEE---VRDL-RERLEELEEERDDLLAEaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRED--- 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  252 vkaKKRLEQEkellhsqntwlNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVED 331
Cdd:PRK02224  351 ---ADDLEER-----------AEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEE 416

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  332 LLTKLKEAKEQQASMEEKFHNELNAhiklsnLYKSAADDSEAKSNELTRAVEElHKLLKEAGEANKAIQDHLLEVEQSKD 411
Cdd:PRK02224  417 LREERDELREREAELEATLRTARER------VEEAEALLEAGKCPECGQPVEG-SPHVETIEEDRERVEELEAELEDLEE 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  412 QMEKemlekigrLEKELENANDLLSATKRKGAILSEEELAAmsptaaavakivkpgmKLTELYNAYVETQDqlllEKLEN 491
Cdd:PRK02224  490 EVEE--------VEERLERAEDLVEAEDRIERLEERREDLE----------------ELIAERRETIEEKR----ERAEE 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  492 KRINKylDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQE----DTDKANKQSSVLERDNRRMEIQ 567
Cdd:PRK02224  542 LRERA--AELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERirtlLAAIADAEDEIERLREKREALA 619

                         490       500
                  ....*....|....*....|....*...
gi 119611609  568 ---------VKDLSQQIRVLLMELEEAR 586
Cdd:PRK02224  620 elnderrerLAEKRERKRELEAEFDEAR 647
PRK01156 PRK01156
chromosome segregation protein; Provisional
 307-856 1.00e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.97  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  307 EVSRLEEQMNGLKTSNEHLQKHV---EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVE 383
Cdd:PRK01156  160 EINSLERNYDKLKDVIDMLRAEIsniDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKS 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  384 ELHKLLKEAGEANKAIQDhlLEVEQSKDQMEKEMLEKIGRLEKELE---------NANDLLSATKRKGAILSEEELaaMS 454
Cdd:PRK01156  240 ALNELSSLEDMKNRYESE--IKTAESDLSMELEKNNYYKELEERHMkiindpvykNRNYINDYFKYKNDIENKKQI--LS 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  455 PTAAAVAKIVKPGMKLTELYNAYvetqDQLLLEKLENKRINKYLDEI----------VKEVEAKapilKRQREEYERAQK 524
Cdd:PRK01156  316 NIDAEINKYHAIIKKLSVLQKDY----NDYIKKKSRYDDLNNQILELegyemdynsyLKSIESL----KKKIEEYSKNIE 387

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  525 avaslsvKLEQAMKEIQRLQE-DTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGN-HVIRDEEVSSADIS 602
Cdd:PRK01156  388 -------RMSAFISEILKIQEiDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNmEMLNGQSVCPVCGT 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  603 SSSEVISQHLVSYRN-----IEELQQQNQRLLVALRELGETREREEQETTSSKITELQL---KLESALTELEQLR----- 669
Cdd:PRK01156  461 TLGEEKSNHIINHYNekksrLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINeynKIESARADLEDIKikine 540

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  670 -----------KSRQHQMQLVDsIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVS--------TPA 730
Cdd:PRK01156  541 lkdkhdkyeeiKNRYKSLKLED-LDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIgfpddksyIDK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  731 PVPVIES---------TEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEkLQEQVTDLRSQNTKISTQLDFASKRYE 801
Cdd:PRK01156  620 SIREIENeannlnnkyNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKE-ITSRINDIEDNLKKSRKALDDAKANRA 698

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 119611609  802 MLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTqDLRGANEKLAVAEVRA 856
Cdd:PRK01156  699 RLESTIEILRTRINELSDRINDINETLESMKKIKKAIG-DLKRLREAFDKSGVPA 752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 82-586 1.00e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    82 QQVLERTELNKLP-KSVQNKLEKFLADQQSEIDGLKGR-------HEKFKVESE--------QQYFEIEKRLSHSQERLV 145
Cdd:pfam15921  202 KKIYEHDSMSTMHfRSLGSAISKILRELDTEISYLKGRifpvedqLEALKSESQnkielllqQHQDRIEQLISEHEVEIT 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   146 NETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIaiqSQFTRTKEELEAEKRDLIRTNERLSQELEY--------L 217
Cdd:pfam15921  282 GLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQL---SDLESTVSQLRSELREAKRMYEDKIEELEKqlvlanseL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   218 TEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKKrlEQEKEL---------------------------LHSQNT 270
Cdd:pfam15921  359 TEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEK--EQNKRLwdrdtgnsitidhlrrelddrnmevqrLEALLK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   271 WLNTELKTKTDELLALGREKgNEILE----LKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEaKEQQASM 346
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGK-NESLEkvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQE-KERAIEA 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   347 EEKFHNELNAHIKLSnlyksaaddseaksneltraVEELHKLLKEageankaiQDHLLEVEQSKDQMEKEMLEK---IGR 423
Cdd:pfam15921  515 TNAEITKLRSRVDLK--------------------LQELQHLKNE--------GDHLRNVQTECEALKLQMAEKdkvIEI 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   424 LEKELENANDLLSATKRK-GAILSEEelaamsptaaavAKIVKpgmkltELYNAYVETQDqllLEKLENKRinkylDEIV 502
Cdd:pfam15921  567 LRQQIENMTQLVGQHGRTaGAMQVEK------------AQLEK------EINDRRLELQE---FKILKDKK-----DAKI 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   503 KEVEAKAPILKRQREEYERAQ----KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNR----RMEIQVKDLSQQ 574
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGserlRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRnkseEMETTTNKLKMQ 700

                          570
                   ....*....|..
gi 119611609   575 IRVLLMELEEAR 586
Cdd:pfam15921  701 LKSAQSELEQTR 712
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
153-441 1.04e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 46.83  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  153 SLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 232
Cdd:COG1340     5 ELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  233 TTKGELQLKLDELQASDVSVKAKKRLEQEKELLHSQNTWlntELKTKTdellaLGREKGNEILelkcnlenkkEEVSRLE 312
Cdd:COG1340    85 EKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEW---RQQTEV-----LSPEEEKELV----------EKIKELE 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  313 EQMNGLKTSNEhLQKHVEDLLTKLKEAKEQQasmeEKFHNELnahiklsnlyKSAADDSEAKSNELTRAVEELHKLLKEA 392
Cdd:COG1340   147 KELEKAKKALE-KNEKLKELRAELKELRKEA----EEIHKKI----------KELAEEAQELHEEMIELYKEADELRKEA 211

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 119611609  393 GEANKAIQDHLLEVEQSKDQmEKEMLEKIGRLEKELENANDLLSATKRK 441
Cdd:COG1340   212 DELHKEIVEAQEKADELHEE-IIELQKELRELRKELKKLRKKQRALKRE 259
46 PHA02562
endonuclease subunit; Provisional
 912-1124 1.08e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  912 LSSQIEKLEHEISHLKKKLEneveqrhTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVA 991
Cdd:PHA02562  179 LNQQIQTLDMKIDHIQQQIK-------TYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIE 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  992 SQSSQ----RTGKGQPSNK-EDVDDLV-------------SQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNk 1053
Cdd:PHA02562  252 DPSAAlnklNTAAAKIKSKiEQFQKVIkmyekggvcptctQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMD- 330

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119611609 1054 ekQVTEEVRKNIEVRLKESAEFQT--QLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQNEVQE 1124
Cdd:PHA02562  331 --EFNEQSKKLLELKNKISTNKQSliTLVDKAKKVKAAIEELQAefvDNAEELAKLQDELDKIVKTKSELVKEKYH 404
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1519-1694 1.09e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.61  E-value: 1.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1519 QYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELK-----ETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQT 1593
Cdd:PRK05771   44 RLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEI 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1594 VQLQ------SELSRLRQ-------------DLQDRTTQEEQLRQQITEKEEKTRKAIVaakskiahLAGVKDQLTKENE 1654
Cdd:PRK05771  124 ERLEpwgnfdLDLSLLLGfkyvsvfvgtvpeDKLEELKLESDVENVEYISTDKGYVYVV--------VVVLKELSDEVEE 195

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 119611609 1655 ELKQrngaLDQQKDELDVRITA--LKSQYEGRISRLERELRE 1694
Cdd:PRK05771  196 ELKK----LGFERLELEEEGTPseLIREIKEELEEIEKERES 233
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 91-671 1.41e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.27  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    91 NKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLkalTE 170
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL---EL 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   171 KNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDvkrlNEKLKESNTTKGELQLKLDELQASDV 250
Cdd:pfam02463  400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEE----KEELEKQELKLLKDELELKKSEDLLK 475

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   251 SVKAKKRLEQEKELLHSQN----TWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQ 326
Cdd:pfam02463  476 ETQLVKLQEQLELLLSRQKleerSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   327 KHVE-DLLTKLKEAKEQQASMEEKF---------------HNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLK 390
Cdd:pfam02463  556 TADEvEERQKLVRALTELPLGARKLrllipklklplksiaVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   391 EAGEANKAIQDHLLE-VEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMK 469
Cdd:pfam02463  636 KLKESAKAKESGLRKgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   470 LTELYNayVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDK 549
Cdd:pfam02463  716 KLEAEE--LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   550 ANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 629
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELL 873

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 119611609   630 VALRELGETREREEQETTSSKITELQLKLESALTELEQLRKS 671
Cdd:pfam02463  874 LKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEK 915
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 377-1281 1.54e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.35  E-value: 1.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   377 ELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK--EMLEKIGRLEKELENANDLlsaTKRKgailsEEELAAMS 454
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKacEIRDQITSKEAQLESSREI---VKSY-----ENELDPLK 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   455 PTAAAVAKIVKPGMKLTELYNAYVETqdqllleKLENKRINKYLDEIVKEVEAKAPilKRQREEYERAQKAVASLSVKLE 534
Cdd:TIGR00606  252 NRLKEIEHNLSKIMKLDNEIKALKSR-------KKQMEKDNSELELKMEKVFQGTD--EQLNDLYHNHQRTVREKERELV 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   535 QAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEargNHVIRDEEVSSADISSSSEVISQHLVS 614
Cdd:TIGR00606  323 DCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQS---LATRLELDGFERGPFSERQIKNFHTLV 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   615 YRNIEELQQQNQRLLVALRE---LGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSivrqrdMYRI 691
Cdd:TIGR00606  400 IERQEDEAKTAAQLCADLQSkerLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGS------SDRI 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   692 LLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVstpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQ 771
Cdd:TIGR00606  474 LELDQELRKAERELSKAEKNSLTETLKKEVKSLQN---------EKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDK 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   772 LEKlQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAV 851
Cdd:TIGR00606  545 MDK-DEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSS 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   852 AEVRAENLKKEKEMlklsEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQ--RLSSQIEKLEHEISHLKKK 929
Cdd:TIGR00606  624 YEDKLFDVCGSQDE----ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSccPVCQRVFQTEAELQEFISD 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   930 LENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSqrtgkgqpsNKEDV 1009
Cdd:TIGR00606  700 LQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN---------DIEEQ 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1010 DDLVSQLRQTEEqvndLKERLKTSTSNVEQYQamvtsleeslnkekQVTEEVRKNIEVRLKESAefQTQLEKKLMEVEKE 1089
Cdd:TIGR00606  771 ETLLGTIMPEEE----SAKVCLTDVTIMERFQ--------------MELKDVERKIAQQAAKLQ--GSDLDRTVQQVNQE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1090 KQELQDDKRRAIESMEqqlseLKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMlhaADVE 1169
Cdd:TIGR00606  831 KQEKQHELDTVVSKIE-----LNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQ---SLIR 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1170 ALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASV 1249
Cdd:TIGR00606  903 EIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTV 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 119611609  1250 kegvqgplNVSLSEEGKSQEQILEILRFIRRE 1281
Cdd:TIGR00606  983 --------NAQLEECEKHQEKINEDMRLMRQD 1006
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1550-1771 1.55e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1550 EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEK----- 1624
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraly 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1625 -------------------------------EEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDvr 1673
Cdd:COG3883    97 rsggsvsyldvllgsesfsdfldrlsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE-- 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1674 itALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTP 1753
Cdd:COG3883   175 --AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAA 252

                         250
                  ....*....|....*...
gi 119611609 1754 SKVTAAAMAGNKSTPRAS 1771
Cdd:COG3883   253 GAAGAAAGSAGAAGAAAG 270
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1006-1673 1.81e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1006 KEDVDDLVS---QLRQTEEQVNDLK------ERLKTSTSNVEQYQAMVTSL-----EESLNKEKQVTEEVRKNIEVRLKE 1071
Cdd:COG4913   231 VEHFDDLERaheALEDAREQIELLEpirelaERYAAARERLAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1072 SAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQN---EVQEALQRASTALSNEQQA----RRDCQ 1144
Cdd:COG4913   311 LERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERrraRLEALLAALGLPLPASAEEfaalRAEAA 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1145 EQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSK---------------MASVRQHLEETTQKAESQ------LLECK 1203
Cdd:COG4913   391 ALLEALEEELEALEEALAEAEAALRDLRRELRELEAeiaslerrksniparLLALRDALAEALGLDEAElpfvgeLIEVR 470

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1204 ---ASWE---ERE------RMLKDEvskcvcrcEDLEKQNRLLHDqiEKLSDKVVAS-VKEGVQGPLNVSLSEEGksqeq 1270
Cdd:COG4913   471 peeERWRgaiERVlggfalTLLVPP--------EHYAAALRWVNR--LHLRGRLVYErVRTGLPDPERPRLDPDS----- 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1271 ILEILRF----IRR--EKEIAEtRFEVAQVESL----RY---------------------RQRVELLERELQELQDSLNA 1319
Cdd:COG4913   536 LAGKLDFkphpFRAwlEAELGR-RFDYVCVDSPeelrRHpraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKLAA 614

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1320 EREKVQVTAKTMAQHEELMKKTETmnvVMETNKMLREEKERLEQ------DLQQMQAKVRKLELDILPLQEANAELSEks 1393
Cdd:COG4913   615 LEAELAELEEELAEAEERLEALEA---ELDALQERREALQRLAEyswdeiDVASAEREIAELEAELERLDASSDDLAA-- 689

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1394 gmlqaekklLEEDVKRWKARNQHLvsqqkdpdTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARsnASLTNNQNLIQS 1473
Cdd:COG4913   690 ---------LEEQLEELEAELEEL--------EEELDELKGEIGRLEKELEQAEEELDELQDRLEA--AEDLARLELRAL 750

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1474 LKEDLNKVRTEK--ETIQKDLDAKIIDIQEKV-KTITQVKKIGRRYKTQYEELKAQQDkvmeTSAQSSGDHQEQHVSVQE 1550
Cdd:COG4913   751 LEERFAAALGDAveRELRENLEERIDALRARLnRAEEELERAMRAFNREWPAETADLD----ADLESLPEYLALLDRLEE 826

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1551 ------MQELKETLNQAETKSkslesqVENLQKTLsekETEARNLQEQTVQLQSEL--------SRLRQDLQDRTTQE-E 1615
Cdd:COG4913   827 dglpeyEERFKELLNENSIEF------VADLLSKL---RRAIREIKERIDPLNDSLkripfgpgRYLRLEARPRPDPEvR 897

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609 1616 QLRQQITEKEEK-TRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNgaldqQKDELDVR 1673
Cdd:COG4913   898 EFRQELRAVTSGaSLFDEELSEARFAALKRLIERLRSEEEESDRRW-----RARVLDVR 951
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1442-1663 1.97e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 1.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1442 RIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLdakiidiqekvktitqvkkigRRYKTQYE 1521
Cdd:COG1579    11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEI---------------------KRLELEIE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1522 ELKAQQDKVmetsaqssgdhQEQHVSVQEMQELketlnqaetksKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELS 1601
Cdd:COG1579    70 EVEARIKKY-----------EEQLGNVRNNKEY-----------EALQKEIESLKRRISDLEDEILELMERIEELEEELA 127

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119611609 1602 RLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLA-GVKDQLTKENEELKQRNGAL 1663
Cdd:COG1579   128 ELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAaKIPPELLALYERIRKRKNGL 190
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 969-1126 2.01e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 2.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  969 LKNAQKEIATLKQHLSNMEVQVASQSSQRTGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTST------SNVEQYQA 1042
Cdd:COG1579    19 LDRLEHRLKELPAELAELEDELAALEARLEAA-----KTELEDLEKEIKRLELEIEEVEARIKKYEeqlgnvRNNKEYEA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1043 MvTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEV 1122
Cdd:COG1579    94 L-QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172


                  ....
gi 119611609 1123 QEAL 1126
Cdd:COG1579   173 PPEL 176
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1510-1707 2.06e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 2.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1510 KKIGRRYKTQYEELKAQQDKVMETSAQssgdHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLqktlsEKETEARNL 1589
Cdd:COG4717    60 KPQGRKPELNLKELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELEELREELEKL-----EKLLQLLPL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1590 QEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDE 1669
Cdd:COG4717   131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAE 210

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 119611609 1670 LDVRITALKSqyegRISRLERELREHQERHLEQRDEPQ 1707
Cdd:COG4717   211 LEEELEEAQE----ELEELEEELEQLENELEAAALEER 244
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
754-936 2.16e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  754 FENYKKEKAENEKIQ--NEQLEKLQEQVTDLRSQNTKISTQLDFASK--RYEMLQDNVEGYRREITSLHERNQKLTATTQ 829
Cdd:COG4913   606 FDNRAKLAALEAELAelEEELAEAEERLEALEAELDALQERREALQRlaEYSWDEIDVASAEREIAELEAELERLDASSD 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  830 kqeqiintmtqDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLL------------AEQRGQNLLLTNLQT- 896
Cdd:COG4913   686 -----------DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEeeldelqdrleaAEDLARLELRALLEEr 754

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 119611609  897 -IQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQ 936
Cdd:COG4913   755 fAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK12704 PRK12704
phosphodiesterase; Provisional
 1559-1690 2.21e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 46.31  E-value: 2.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1559 NQAETKSKSLESQVEnlqKTLSEKETEARNL-QEQTVQLQSELSRLRQDLQDRTTQEeqlRQQITEKEEKTRKaivaaks 1637
Cdd:PRK12704   27 KIAEAKIKEAEEEAK---RILEEAKKEAEAIkKEALLEAKEEIHKLRNEFEKELRER---RNELQKLEKRLLQ------- 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 119611609 1638 KIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER 1690
Cdd:PRK12704   94 KEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELER 146
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1045-1626 2.60e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.57  E-value: 2.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1045 TSLEESLNKEKQVTEEVRKNIEVrlKESAEFQTQL---EKKLMEVEKEKQELQDDKRRAIESME-------------QQL 1108
Cdd:PRK02224  176 LGVERVLSDQRGSLDQLKAQIEE--KEEKDLHERLnglESELAELDEEIERYEEQREQARETRDeadevleeheerrEEL 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1109 SELKKTLSSVQNEVQEAlQRASTALSNEQQARRDCQEQAKiavEAQNKYERELMLHAADVEALQAAKEQVSKmasvrqHL 1188
Cdd:PRK02224  254 ETLEAEIEDLRETIAET-EREREELAEEVRDLRERLEELE---EERDDLLAEAGLDDADAEAVEARREELED------RD 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1189 EETTQKAESQLLECKASWEERERMLKDevskcvcrCEDLEKQNRLLHDQIEKLsDKVVASVKEGVqgplnvslseeGKSQ 1268
Cdd:PRK02224  324 EELRDRLEECRVAAQAHNEEAESLRED--------ADDLEERAEELREEAAEL-ESELEEAREAV-----------EDRR 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1269 EQILEIlrfiRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELM---KKTETMN 1345
Cdd:PRK02224  384 EEIEEL----EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeagKCPECGQ 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1346 VV-----METNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEAnAELSEKSGMLQAEKKLLEE--DVKRWKARNQHLV 1418
Cdd:PRK02224  460 PVegsphVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDL-VEAEDRIERLEERREDLEEliAERRETIEEKRER 538

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1419 SQQKDPDTEEYRkllSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLkedlNKVRTEKETIQkDLDAKIID 1498
Cdd:PRK02224  539 AEELRERAAELE---AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL----ERIRTLLAAIA-DAEDEIER 610

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1499 IQEKVKTITQVKKIGRryktqyEELKAQQDKVMETSAQSSGDhqeqhvSVQEMQELKETLnqaetkskslESQVENLQKT 1578
Cdd:PRK02224  611 LREKREALAELNDERR------ERLAEKRERKRELEAEFDEA------RIEEAREDKERA----------EEYLEQVEEK 668

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 119611609 1579 LSEKETEARNLQEQTVQLQSELSRL------RQDLQDRTTQEEQLRQQITEKEE 1626
Cdd:PRK02224  669 LDELREERDDLQAEIGAVENELEELeelrerREALENRVEALEALYDEAEELES 722
PRK09039 PRK09039
peptidoglycan -binding protein;
1550-1670 2.76e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 45.73  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1550 EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKT- 1628
Cdd:PRK09039   61 QIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALAQVe 140

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 119611609 1629 --RKAIVAAKSKIAHLAGVKDQLTKENEE-------LKQR-NGALDQQKDEL 1670
Cdd:PRK09039  141 llNQQIAALRRQLAALEAALDASEKRDREsqakiadLGRRlNVALAQRVQEL 192
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 127-623 2.78e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.50  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   127 EQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQD--RNIAIQSQFTRTKEELEAEKRDLI 204
Cdd:TIGR00618  238 TQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQIEQQAQRIHTELQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   205 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKKRLEQEKELLHSQNTW------LNTELKT 278
Cdd:TIGR00618  318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLqqqkttLTQKLQS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   279 KTDELLALGREKGnEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHI 358
Cdd:TIGR00618  398 LCKELDILQREQA-TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQ 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   359 KLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQD-HLLEVEQSKDQmekEMLEKIGRLEKELENANDLLSA 437
Cdd:TIGR00618  477 TKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDiDNPGPLTRRMQ---RGEQTYAQLETSEEDVYHQLTS 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   438 TKRKGAILSEEELAAMSPTaaavakivkpgMKLTELYNAYVETQDQLLleklenKRINKYLDEIVKEVEAKAPILKRQRE 517
Cdd:TIGR00618  554 ERKQRASLKEQMQEIQQSF-----------SILTQCDNRSKEDIPNLQ------NITVRLQDLTEKLSEAEDMLACEQHA 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   518 EYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNR---RMEIQVKDLSQQIRVLLMELEEARGNHVIRDE 594
Cdd:TIGR00618  617 LLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVRehaLSIRVLPKELLASRQLALQKMQSEKEQLTYWK 696

                          490       500
                   ....*....|....*....|....*....
gi 119611609   595 EVSSADISSSSEVISQHLVSYRNIEELQQ 623
Cdd:TIGR00618  697 EMLAQCQTLLRELETHIEEYDREFNEIEN 725
PRK11281 PRK11281
mechanosensitive channel MscK;
58-380 2.90e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 46.44  E-value: 2.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   58 FFSASTPSAAATGVPGPT--DMAAVLQQVLERTELNKLPKSVQNKLEKFLA------DQQSEIDGLKGRHEKFKVESEQQ 129
Cdd:PRK11281   20 LCLSSAFARAASNGDLPTeaDVQAQLDALNKQKLLEAEDKLVQQDLEQTLAlldkidRQKEETEQLKQQLAQAPAKLRQA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  130 YFEIEkRLSHSQERLVNETRECQSLRlELE-KLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEEL-EAEKRdlirtn 207
Cdd:PRK11281  100 QAELE-ALKDDNDEETRETLSTLSLR-QLEsRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALyANSQR------ 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  208 erlSQEleyltedvkrLNEKLKESNTTKGELqlkldelqasdvSVKAKKRLEQEKELLHSQNTWLNTELKTkTDELLALG 287
Cdd:PRK11281  172 ---LQQ----------IRNLLKGGKVGGKAL------------RPSQRVLLQAEQALLNAQNDLQRKSLEG-NTQLQDLL 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  288 REKGNEilelkcnlenKKEEVSRLEEQMNGLKT--SNEHL---QKHVEDLLTKLKEAKEQQASMeekFHNELNAHIKLSN 362
Cdd:PRK11281  226 QKQRDY----------LTARIQRLEHQLQLLQEaiNSKRLtlsEKTVQEAQSQDEAARIQANPL---VAQELEINLQLSQ 292

                         330
                  ....*....|....*...
gi 119611609  363 LYKSAADdseaKSNELTR 380
Cdd:PRK11281  293 RLLKATE----KLNTLTQ 306
PTZ00121 PTZ00121
MAEBL; Provisional
 855-1496 2.94e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 2.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  855 RAENLKKEKEMLKLSEVRLS---QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEH--EISHLKKK 929
Cdd:PTZ00121 1244 KAEEERNNEEIRKFEEARMAhfaRRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKK 1323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  930 LENEVEQRHTLTRNLDvqllDTKRQLDTETNLHLNTKELLKNAQK--EIATLKQHLSNMEVQVASQSSQRTGKGQPSNK- 1006
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAE----EAKKAAEAAKAEAEAAADEAEAAEEkaEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKk 1399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1007 -EDVDDLVSQLRQTEEQVNDLKErLKTSTSNVEQYQAMVTSLEESlnkeKQVTEEVRKNIEVRLKESAEFQTQLEKKLME 1085
Cdd:PTZ00121 1400 aEEDKKKADELKKAAAAKKKADE-AKKKAEEKKKADEAKKKAEEA----KKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1086 VEKEKQELQ--DDKRRAIESMEQQLSELKKtlSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1163
Cdd:PTZ00121 1475 AKKKAEEAKkaDEAKKKAEEAKKKADEAKK--AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1164 HAADV-------EALQAAKEQVSKMASVRQhLEETTQKAESQLLECKASWEERERMLKDEVSKC---VCRCEDLEKQNRL 1233
Cdd:PTZ00121 1553 KAEELkkaeekkKAEEAKKAEEDKNMALRK-AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAeeaKIKAEELKKAEEE 1631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1234 lHDQIEKLSDKVVASVKEGVQ-----GPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVA--QVESLRYRQRVELL 1306
Cdd:PTZ00121 1632 -KKKVEQLKKKEAEEKKKAEElkkaeEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALkkEAEEAKKAEELKKK 1710

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1307 ERELQELQDSLNAEREKVQVTAktmaqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEAN 1386
Cdd:PTZ00121 1711 EAEEKKKAEELKKAEEENKIKA------EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1387 AELSEKSGMLQAEKKLLE-----EDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEV---HTKRIQQLTEEIGRLKAEIA 1458
Cdd:PTZ00121 1785 LDEEDEKRRMEVDKKIKDifdnfANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMqleEADAFEKHKFNKNNENGEDG 1864

                         650       660       670
                  ....*....|....*....|....*....|....*...
gi 119611609 1459 RSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKI 1496
Cdd:PTZ00121 1865 NKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREI 1902
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1059-1581 3.23e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 3.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1059 EEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDdKRRAIESMEQQLSELKKTLSSVQNEVQEaLQRASTALSNEQQ 1138
Cdd:COG4717    49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEE-KEEEYAELQEELEELEEELEELEAELEE-LREELEKLEKLLQ 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1139 ARRDCQEQAKIAVEAQNKYERelmLHAADvEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVS 1218
Cdd:COG4717   127 LLPLYQELEALEAELAELPER---LEELE-ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1219 KCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLR 1298
Cdd:COG4717   203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1299 YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKL--E 1376
Cdd:COG4717   283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeE 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1377 LDILPLQEANAELSEKSGMlqaekklleedvkrwkarnqhlvsqqkdPDTEEYRKLLSEKEvhtkRIQQLTEEIGRLKAE 1456
Cdd:COG4717   363 LQLEELEQEIAALLAEAGV----------------------------EDEEELRAALEQAE----EYQELKEELEELEEQ 410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1457 IARSNASLTNNQNLIQ--SLKEDLNKVRTEKETIQKDLDAKIidiQEKVKTITQVKKIGRryKTQYEELKAQQdkvmets 1534
Cdd:COG4717   411 LEELLGELEELLEALDeeELEEELEELEEELEELEEELEELR---EELAELEAELEQLEE--DGELAELLQEL------- 478

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 119611609 1535 aqssgdhqeqhvsvqemQELKETLNQAETKSKSLESQVENLQKTLSE 1581
Cdd:COG4717   479 -----------------EELKAELRELAEEWAALKLALELLEEAREE 508
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1040-1455 3.32e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 3.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1040 YQAMVTSLEESLNKEKQvtEEVRKNIEVRLKESAEFQtQLEKKLMEVEKEKQELQDdKRRAIESMEQQLSELKKTLSSVQ 1119
Cdd:COG4717    40 LAFIRAMLLERLEKEAD--ELFKPQGRKPELNLKELK-ELEEELKEAEEKEEEYAE-LQEELEELEEELEELEAELEELR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1120 NEVqEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL 1199
Cdd:COG4717   116 EEL-EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1200 LECKASWEE---RERMLKDEVSKCVCRCEDLEKQ------NRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQ 1270
Cdd:COG4717   195 QDLAEELEElqqRLAELEEELEEAQEELEELEEEleqlenELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILT 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1271 ILEIL-----------RFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMK 1339
Cdd:COG4717   275 IAGVLflvlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR 354

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1340 KTETMNVVMETNKMLREEKERLE-----------------QDLQQMQAKVRKLELDILPLQEAN---------AELSEKS 1393
Cdd:COG4717   355 EAEELEEELQLEELEQEIAALLAeagvedeeelraaleqaEEYQELKEELEELEEQLEELLGELeellealdeEELEEEL 434

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119611609 1394 GMLQAEKKLLEEDVKRWKARNQHLVSQQKD-PDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKA 1455
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQlEEDGELAELLQELEELKAELRELAEEWAALKL 497
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 100-671 3.71e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 3.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   100 KLEKFLADQQSEIDGLKgrHEKFKVESEQQYFEIEKrlsHSQERLVNETRecqSLRLELEKLNNQLKALTEKNKELEIA- 178
Cdd:TIGR04523  149 KKEKELEKLNNKYNDLK--KQKEELENELNLLEKEK---LNIQKNIDKIK---NKLLKLELLLSNLKKKIQKNKSLESQi 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   179 ---QDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAk 255
Cdd:TIGR04523  221 selKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISD- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   256 krLEQEKEllHSQNTWLNTELKTKTDELlalgREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 335
Cdd:TIGR04523  300 --LNNQKE--QDWNKELKSELKNQEKKL----EEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNE 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   336 LKEAKEQQasmEEKFHNELNAHIKLSNLyKSAADDSEAKSNELTravEELHKLLKEAGEANKAIQDHLLEVEQSKDQMeK 415
Cdd:TIGR04523  372 IEKLKKEN---QSYKQEIKNLESQINDL-ESKIQNQEKLNQQKD---EQIKKLQQEKELLEKEIERLKETIIKNNSEI-K 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   416 EMLEKIGRLEKELENANDLLSATKRKGAILSEEelaamsptaaavakivkpgmkltelYNAYVETQDQLLLEKLENKRIN 495
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRS-------------------------INKIKQNLEQKQKELKSKEKEL 498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   496 KYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRlQEDTDKANKQSSVLERDNRRMEIQVKDLSQQI 575
Cdd:TIGR04523  499 KKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED-ELNKDDFELKKENLEKEIDEKNKEIEELKQTQ 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   576 RVLLMELEEArgnhvirdEEVSSADISSSSEVISQHLVSYRNIEELQQQnqrllvalrelgetreREEQETTSSKITELQ 655
Cdd:TIGR04523  578 KSLKKKQEEK--------QELIDQKEKEKKDLIKEIEEKEKKISSLEKE----------------LEKAKKENEKLSSII 633

                          570
                   ....*....|....*.
gi 119611609   656 LKLESALTELEQLRKS 671
Cdd:TIGR04523  634 KNIKSKKNKLKQEVKQ 649
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1471-1736 4.13e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 45.58  E-value: 4.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1471 IQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELK-----------AQQDKVMETSAQSSg 1539
Cdd:pfam10174  242 ISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKqelskkesellALQTKLETLTNQNS- 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1540 dHQEQHVSVqemqeLKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDrttqeeqLRQ 1619
Cdd:pfam10174  321 -DCKQHIEV-----LKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRD-------LKD 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1620 QITEKEektRKAIVAAKsKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALK---SQYEGRISRL----EREL 1692
Cdd:pfam10174  388 MLDVKE---RKINVLQK-KIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEealSEKERIIERLkeqrERED 463

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 119611609  1693 REHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIAST 1736
Cdd:pfam10174  464 RERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASS 507
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 745-1291 4.51e-04

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 45.98  E-value: 4.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  745 AALKQLQEIFENYKKE--KAENEKIQNEQLEKLQEQVTDLRSQNTKIST--QLDFASKRYEMLQDNVEgyrreitSLHER 820
Cdd:PTZ00440  833 EELKQLLQKFPTEDENlnLKELEKEFNENNQIVDNIIKDIENMNKNINIikTLNIAINRSNSNKQLVE-------HLLNN 905

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  821 NQKLTATTQKQEQIINTmtQDLRGANEKLAVAEvraeNLKKEKEML--KLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQ 898
Cdd:PTZ00440  906 KIDLKNKLEQHMKIINT--DNIIQKNEKLNLLN----NLNKEKEKIekQLSDTKINNLKMQIEKTLEYYDKSKENINGND 979

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  899 GI-LERSETETK--QRLSSQIEKLEHEISHLKKKLENEVEQRHTltrnlDVQLLDTKRQLDTETNLHLNTKELLKNAQKE 975
Cdd:PTZ00440  980 GThLEKLDKEKDewEHFKSEIDKLNVNYNILNKKIDDLIKKQHD-----DIIELIDKLIKEKGKEIEEKVDQYISLLEKM 1054

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  976 IATLKQHLSNMEVQvASQSSQRTGKGQpSNKEDVDDLVSQLRQTEEQVNDLKERlktSTSNVEQYQAMVTSLEESLNKEK 1055
Cdd:PTZ00440 1055 KTKLSSFHFNIDIK-KYKNPKIKEEIK-LLEEKVEALLKKIDENKNKLIEIKNK---SHEHVVNADKEKNKQTEHYNKKK 1129

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1056 QVTEEVRKNIEVRLKESAEFQTQlEKKLMEVEKEKQELqddKRRAIESMEQQLSELKKTLSSVQNEVQ---EALQRASTA 1132
Cdd:PTZ00440 1130 KSLEKIYKQMEKTLKELENMNLE-DITLNEVNEIEIEY---ERILIDHIVEQINNEAKKSKTIMEEIEsykKDIDQVKKN 1205

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1133 LSNEQQARRDCQEQAKIAVEAQNKYER--ELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKA-------ESQLLECK 1203
Cdd:PTZ00440 1206 MSKERNDHLTTFEYNAYYDKATASYENieELTTEAKGLKGEANRSTNVDELKEIKLQVFSYLQQVikennkmENALHEIK 1285

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1204 ASWE-----ERERMLKdEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFI 1278
Cdd:PTZ00440 1286 NMYEflisiDSEKILK-EILNSTKKAEEFSNDAKKELEKTDNLIKQVEAKIEQAKEHKNKIYGSLEDKQIDDEIKKIEQI 1364

                         570
                  ....*....|...
gi 119611609 1279 RreKEIAETRFEV 1291
Cdd:PTZ00440 1365 K--EEISNKRKEI 1375
Filament pfam00038
Intermediate filament protein;
840-1162 4.65e-04

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 44.91  E-value: 4.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   840 QDLRGANEKLAVAEVRAENLKKEKEMLklsEVRLSQQRESLLAEQRG-QNLLLTNLQTIQGILERSETEtKQRLSSQIEK 918
Cdd:pfam00038    4 EQLQELNDRLASYIDKVRFLEQQNKLL---ETKISELRQKKGAEPSRlYSLYEKEIEDLRRQLDTLTVE-RARLQLELDN 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   919 LEHEISHLKKKLENEVEQRhtltRNLDVQLLDTKRQLDTETnlhLNTKELlknaQKEIATLKqhlsnmevqvasqssqrt 998
Cdd:pfam00038   80 LRLAAEDFRQKYEDELNLR----TSAENDLVGLRKDLDEAT---LARVDL----EAKIESLK------------------ 130

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   999 gkgqpsnkedvDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEvrknIEVRLKESAE--FQ 1076
Cdd:pfam00038  131 -----------EELAFLKKNHEEEVRELQAQVSDTQVNVEMDAARKLDLTSALAEIRAQYEE----IAAKNREEAEewYQ 195

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1077 TQLEKKLMEVEKEKQELQDDK------RRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQ---A 1147
Cdd:pfam00038  196 SKLEELQQAAARNGDALRSAKeeitelRRTIQSLEIELQSLKKQKASLERQLAETEERYELQLADYQELISELEAElqeT 275

                          330
                   ....*....|....*
gi 119611609  1148 KIAVEAQNKYERELM 1162
Cdd:pfam00038  276 RQEMARQLREYQELL 290
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1425-1720 4.73e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 4.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1425 DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEketiqkdldakiidiqEKVK 1504
Cdd:pfam17380  297 EQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE----------------ERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1505 TITQVKKigrryktqyEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKEt 1584
Cdd:pfam17380  361 ELERIRQ---------EEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQE- 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1585 EARNLQEQTVQLQS--ELSRLRQDLQDRTTQEEQLRQQiteKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGA 1662
Cdd:pfam17380  431 EARQREVRRLEEERarEMERVRLEEQERQQQVERLRQQ---EEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA 507

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119611609  1663 LDQQKD-------ELDVRITALKSQYEGRISRLERElrehQERHLEQRDEPQEPSNKVPEQQRQI 1720
Cdd:pfam17380  508 MIEEERkrkllekEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRL 568
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
 247-357 5.01e-04

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 45.44  E-value: 5.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   247 ASDVSVKAKKRLEQEKELLHSQNTWLNTELKTKTDELLALG---REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNE 323
Cdd:pfam05911  675 SNDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKsqlQESEQLIAELRSELASLKESNSLAETQLKCMAESYE 754

                           90       100       110
                   ....*....|....*....|....*....|....
gi 119611609   324 HLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAH 357
Cdd:pfam05911  755 DLETRLTELEAELNELRQKFEALEVELEEEKNCH 788
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 366-586 5.06e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  366 SAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMeKEMLEKIGRLEKELENANDLLSATKRKGAIL 445
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  446 SEEELAAMSPTAAAVAKIVKPGM--KLTELYNAYVETQDQLLLEKLenKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 523
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDAVRRLQYL--KYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609  524 KAVASLSVKLEQAMKEIQRLQEDTDKA----NKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR 586
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLlarlEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
COG5022 COG5022
Myosin heavy chain [General function prediction only];
488-1144 5.43e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.45  E-value: 5.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  488 KLENKRINKYLDEivKEVEAKAPILKRQREEYERAQKAVASL---------SVKLEQAMKEIQRLQEDTDKANKQSSVLE 558
Cdd:COG5022   825 TIKREKKLRETEE--VEFSLKAEVLIQKFGRSLKAKKRFSLLkketiylqsAQRVELAERQLQELKIDVKSISSLKLVNL 902

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  559 RDnrrmEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHlvSYRNIEELQQQNqrllvalrelget 638
Cdd:COG5022   903 EL----ESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYV--KLPELNKLHEVE------------- 963

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  639 rereeqettsSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSqttgvAIPLHASSLDDVSLASTPK 718
Cdd:COG5022   964 ----------SKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYG-----ALQESTKQLKELPVEVAEL 1028

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  719 RPSTSQTVSTPApvpviesTEAIEAKAA-LKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTqldFAS 797
Cdd:COG5022  1029 QSASKIISSEST-------ELSILKPLQkLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKT---INV 1098

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  798 KRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEqIINTMTQDLRGANEKLAVAEVRAENLKKEKEMlklsEVRLSQQR 877
Cdd:COG5022  1099 KDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISK-FLSQLVNTLEPVFQKLSVLQLELDGLFWEANL----EALPSPPP 1173

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  878 ESLLAEQRgqnLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKL-ENEVEQRH------TLTRNLDVQLLD 950
Cdd:COG5022  1174 FAALSEKR---LYQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLkKLISEGWVpteystSLKGFNNLNKKF 1250

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  951 TKRQLDTETNLHLNTKEL-----LKNAQKEI--ATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQ- 1022
Cdd:COG5022  1251 DTPASMSNEKLLSLLNSIdnllsSYKLEEEVlpATINSLLQYINVGLFNALRTKASSLRWKSATEVNYNSEELDDWCREf 1330

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1023 -VNDLKERLKtstsNVEQYQAMVTSLEESLNKEKQVTEEVR--KNIEVR-LKES---AEFQTQLEKKLME-----VEKEK 1090
Cdd:COG5022  1331 eISDVDEELE----ELIQAVKVLQLLKDDLNKLDELLDACYslNPAEIQnLKSRydpADKENNLPKEILKkiealLIKQE 1406

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609 1091 QELQDDKRRAIESMEQQLSELKKTLSSVQNEV---QEALQRASTALSNEQQARRDCQ 1144
Cdd:COG5022  1407 LQLSLEGKDETEVHLSEIFSEEKSLISLDRNSiykEEVLSSLSALLTKEKIALLDRK 1463
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
105-342 5.74e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 5.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  105 LADQQSEIDGLKGRH---EKFKVESEQQYFEIEKRLSHSQeRLVNETREC---QSLRLELEKLNNQLKALTEKNKELEIA 178
Cdd:COG4913   612 LAALEAELAELEEELaeaEERLEALEAELDALQERREALQ-RLAEYSWDEidvASAEREIAELEAELERLDASSDDLAAL 690

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  179 QDRNIAIQSQFtrtkEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKL-----KESNTTKGELQLKLDELQASDVSVK 253
Cdd:COG4913   691 EEQLEELEAEL----EELEEELDELKGEIGRLEKELEQAEEELDELQDRLeaaedLARLELRALLEERFAAALGDAVERE 766

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  254 AKKRLEQEKELLHSQNTWLNTELKTK--------TDELLALGR--EKGNEILELKCNLENkkEEVSRLEEQMNGLKTSNE 323
Cdd:COG4913   767 LRENLEERIDALRARLNRAEEELERAmrafnrewPAETADLDAdlESLPEYLALLDRLEE--DGLPEYEERFKELLNENS 844

                         250
                  ....*....|....*....
gi 119611609  324 HlqKHVEDLLTKLKEAKEQ 342
Cdd:COG4913   845 I--EFVADLLSKLRRAIRE 861
mukB PRK04863
chromosome partition protein MukB;
1321-1720 7.43e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 7.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1321 REKVQVTAKTMAQHEELMkkTETMNVVmeTNKMLREEKER---LEQDL---QQMQAKVRKLELDilplQEANAELSEKSG 1394
Cdd:PRK04863  246 LEAIRVTQSDRDLFKHLI--TESTNYV--AADYMRHANERrvhLEEALelrRELYTSRRQLAAE----QYRLVEMARELA 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1395 MLQAEKKLLEEDvkrWKARNQHLVSqqkdpdteeyrkllsekeVHTKRIQQltEEIGRLKAEIARSNASLTNNQNLIQSL 1474
Cdd:PRK04863  318 ELNEAESDLEQD---YQAASDHLNL------------------VQTALRQQ--EKIERYQADLEELEERLEEQNEVVEEA 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1475 KEDLNKVRTEKETIQKDLD---AKIIDIQEKVktITQVKKIG--RRYKTQYEELKAQQDkVMETSAQSSGDHQEQHVSvq 1549
Cdd:PRK04863  375 DEQQEENEARAEAAEEEVDelkSQLADYQQAL--DVQQTRAIqyQQAVQALERAKQLCG-LPDLTADNAEDWLEEFQA-- 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1550 EMQELKETLNQAETKSKSLE----------------------SQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDL 1607
Cdd:PRK04863  450 KEQEATEELLSLEQKLSVAQaahsqfeqayqlvrkiagevsrSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRL 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1608 QDRTTQeEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQ------Y 1681
Cdd:PRK04863  530 RQQQRA-ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARapawlaA 608

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 119611609 1682 EGRISRLERELREHQE----------RHLEQRDEPQEPSNKVPEQQRQI 1720
Cdd:PRK04863  609 QDALARLREQSGEEFEdsqdvteymqQLLERERELTVERDELAARKQAL 657
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1317-1481 8.83e-04

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 44.63  E-value: 8.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1317 LNAEREKVQVTAKTMAQHEELMKKTE-TMNVVMETNKMLREEKERLEQDLqqmqaKVRKLELDILPLQEANaeLSEKSGM 1395
Cdd:pfam05667  337 LEELQEQLEDLESSIQELEKEIKKLEsSIKQVEEELEELKEQNEELEKQY-----KVKKKTLDLLPDAEEN--IAKLQAL 409

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1396 LQAEKKLLEEDVKRWKARnqhlvsqqKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1475
Cdd:pfam05667  410 VDASAQRLVELAGQWEKH--------RVPLIEEYRALKEAKSNKEDESQRKLEEIKELREKIKEVAEEAKQKEELYKQLV 481


                   ....*.
gi 119611609  1476 EDLNKV 1481
Cdd:pfam05667  482 AEYERL 487
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 78-289 8.88e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   78 AAVLQQVLERTELNKLPKSVQNKL---EKFLADQQSEIDGLKG---RHEKFKVESEQQYFEIEKRLSHSQERLvnetrec 151
Cdd:COG4942    13 LAAAAQADAAAEAEAELEQLQQEIaelEKELAALKKEEKALLKqlaALERRIAALARRIRALEQELAALEAEL------- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  152 QSLRLELEKLNNQLKALTEKNKELEIAQDRNiaiqSQFTRTKEELEAEK-RDLIRTNERLSQELEYLTEDVKRLNEKLKE 230
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELAELLRALYRL----GRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAE 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  231 SNTTKGELQLKLDELQASDVSVKA-KKRLEQEKELLHSQNTWLNTELKTKTDELLALGRE 289
Cdd:COG4942   162 LAALRAELEAERAELEALLAELEEeRAALEALKAERQKLLARLEKELAELAAELAELQQE 221
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 164-398 1.23e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  164 QLKALTEKNKELEIAQDRniaiQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLD 243
Cdd:COG4942    18 QADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  244 ELQasdvsvkakKRLEQEKELLHSQNTWLNTELKTKTDELLaLGREKGNEILE----LKCNLENKKEEVSRLEEQMNGLK 319
Cdd:COG4942    94 ELR---------AELEAQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRrlqyLKYLAPARREQAEELRADLAELA 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609  320 TSNEHLQKHVEDLLTKLKEAKEQQASMEEkfhnELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 398
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEA----LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK12705 PRK12705
hypothetical protein; Provisional
 1573-1694 1.25e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 43.93  E-value: 1.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1573 ENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKskIAHLAGVKDQLTKE 1652
Cdd:PRK12705   33 KEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDAR--AEKLDNLENQLEER 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 119611609 1653 NEELKQRNGALDQQKDELD---VRITALkSQYEGR---ISRLERELRE 1694
Cdd:PRK12705  111 EKALSARELELEELEKQLDnelYRVAGL-TPEQARkllLKLLDAELEE 157
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1349-1571 1.36e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1349 ETNKMLREEKERLEQDLQQMQAKVR--KLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDT 1426
Cdd:COG3206   175 KALEFLEEQLPELRKELEEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1427 EEYRKLLSEkevhtkRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEketIQKDLDAKIIDIQEKVKTI 1506
Cdd:COG3206   255 ALPELLQSP------VIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ---LQQEAQRILASLEAELEAL 325

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119611609 1507 tqvkkigrryKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQ 1571
Cdd:COG3206   326 ----------QAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLA 380
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1005-1173 1.41e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1005 NKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRlkesaefqtQLEKKLM 1084
Cdd:COG3206   203 QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQ---------QLRAQLA 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1085 EVEKEKQELQ---DDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYEREL 1161
Cdd:COG3206   274 ELEAELAELSaryTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAEL 353

                         170
                  ....*....|..
gi 119611609 1162 MLHAADVEALQA 1173
Cdd:COG3206   354 RRLEREVEVARE 365
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1359-1715 1.45e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 44.27  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1359 ERLEQDLQQMQAKVRKLELDIlplqeanaelSEKSGMLQAEKKLLEEDVKR--------------WKARNQHLVSQQKDP 1424
Cdd:PTZ00108 1002 GKLERELARLSNKVRFIKHVI----------NGELVITNAKKKDLVKELKKlgyvrfkdiikkksEKITAEEEEGAEEDD 1071

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1425 D------------TEEYRKLLSekevhtKRIQQLTEE-IGRLKAEIARSNASLTN--NQNLIQSLKEDLNKVRTEKETIQ 1489
Cdd:PTZ00108 1072 EaddeddeeelgaAVSYDYLLS------MPIWSLTKEkVEKLNAELEKKEKELEKlkNTTPKDMWLEDLDKFEEALEEQE 1145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1490 KDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLE 1569
Cdd:PTZ00108 1146 EVEEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQ 1225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1570 SQVENLQKTLSEKETEARNLQEQTVQLQSELS---RLRQDLQDRTTQEEQLR-------QQITEKEEKTRKAIVAAKSKI 1639
Cdd:PTZ00108 1226 EDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNdefSSDDLSKEGKPKNAPKRvsavqysPPPPSKRPDGESNGGSKPSSP 1305

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119611609 1640 AHlAGVKDQLTKENEELKQRNGALDqqKDELDVRITALKSQYEGR-ISRLERELREHQERHLEQRDEPQEPSNKVPE 1715
Cdd:PTZ00108 1306 TK-KKVKKRLEGSLAALKKKKKSEK--KTARKKKSKTRVKQASASqSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDE 1379
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 87-230 1.49e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   87 RTELNKLPKSVQnKLEKFLADQQSEIDGLKGRHEKFKVE---SEQQYFEIEKRLSHSQERL--VNETRECQSLRLELEKL 161
Cdd:COG1579    23 EHRLKELPAELA-ELEDELAALEARLEAAKTELEDLEKEikrLELEIEEVEARIKKYEEQLgnVRNNKEYEALQKEIESL 101

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119611609  162 NNQL----KALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKE 230
Cdd:COG1579   102 KRRIsdleDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 98-668 1.51e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    98 QNKLEKFLADQQSEIDGLKGRHEKFKVESEQQyfeiekrlshsQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEI 177
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEE-----------RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   178 AQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDEL-----QASDVSV 252
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQewkleQLAADLS 465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   253 KAKKRLEQEKELLHSQNTWLnTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVE-- 330
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKEL-SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEva 544

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   331 ------------DLLTK-----LKEAKEQQASM-------------------------------EEKFHN---------- 352
Cdd:TIGR02169  545 agnrlnnvvvedDAVAKeaielLKRRKAGRATFlplnkmrderrdlsilsedgvigfavdlvefDPKYEPafkyvfgdtl 624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   353 ---------ELNAHIKL-----------------SNLYKSAADDS---EAKSNELTRAVEELHKLLKEAGEANKAIQDHL 403
Cdd:TIGR02169  625 vvedieaarRLMGKYRMvtlegelfeksgamtggSRAPRGGILFSrsePAELQRLRERLEGLKRELSSLQSELRRIENRL 704

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   404 LEVEQSKDQMEKEMLEK---IGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELynayvet 480
Cdd:TIGR02169  705 DELSQELSDASRKIGEIekeIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL------- 777

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   481 qdQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDtdkankqssvlerd 560
Cdd:TIGR02169  778 --EEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ-------------- 841

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   561 NRRMEIQVKDLSQQIRVLLMELEEArgnhvirdEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELgetre 640
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEEL--------EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL----- 908

                          650       660
                   ....*....|....*....|....*...
gi 119611609   641 REEQETTSSKITELQLKLESALTELEQL 668
Cdd:TIGR02169  909 EAQIEKKRKRLSELKAKLEALEEELSEI 936
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1417-1727 1.52e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1417 LVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQnliQSLKEDLNKVRTEKETIQKDLDAKI 1496
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQ---LKEKLELEEEYLLYLDYLKLNEERI 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1497 IDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENL 1575
Cdd:pfam02463  240 DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAkEEEELKSELLKLERRKVDDEEKLKES 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1576 QKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENE- 1654
Cdd:pfam02463  320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEl 399

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119611609  1655 --ELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPA 1727
Cdd:pfam02463  400 ksEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 747-1108 1.85e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 43.52  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   747 LKQLQEIFENYKKeKAENEKIQNEQLEKLQEQVTDLRSQNTkistQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTA 826
Cdd:pfam05622  130 VKKLEATVETYKK-KLEDLGDLRRQVKLLEERNAEYMQRTL----QLEEELKKANALRGQLETYKRQVQELHGKLSEESK 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   827 TTQKQEQIINTMtqdlrganeklavaEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET 906
Cdd:pfam05622  205 KADKLEFEYKKL--------------EEKLEALQKEKERLIIERDTLRETNEELRCAQLQQAELSQADALLSPSSDPGDN 270

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   907 ETKQRLSSQ----IEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEtnlhlntkelLKNAQKEIATLKQH 982
Cdd:pfam05622  271 LAAEIMPAEirekLIRLQHENKMLRLGQEGSYRERLTELQQLLEDANRRKNELETQ----------NRLANQRILELQQQ 340

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   983 LSNMEVQVASQSSQRTGKGQPSNK-----EDVDDLVSQLRQTEEQVNDLKERLKTSTS-NVEQYQAMVT-------SLEE 1049
Cdd:pfam05622  341 VEELQKALQEQGSKAEDSSLLKQKleehlEKLHEAQSELQKKKEQIEELEPKQDSNLAqKIDELQEALRkkdedmkAMEE 420

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119611609  1050 SLNKEKQVTEEVRKNIEVRLKESAEFQTQ-LEKKLMEVEKEKQELQDD--KRRAIESMEQQL 1108
Cdd:pfam05622  421 RYKKYVEKAKSVIKTLDPKQNPASPPEIQaLKNQLLEKDKKIEHLERDfeKSKLQREQEEKL 482
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 81-348 1.88e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    81 LQQVLERTELNKLPKSVQnKLEKFLADQQSEIDGLKGRHEKFKV---ESEQQYFEIEKRLSHSQERLVNETRECQ-SLRL 156
Cdd:TIGR02169  216 LLKEKREYEGYELLKEKE-ALERQKEAIERQLASLEEELEKLTEeisELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   157 ELEKLNNQL----KALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER-----------------LSQELE 215
Cdd:TIGR02169  295 KIGELEAEIasleRSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRrdklteeyaelkeeledLRAELE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   216 YLTEDVKRLNEKLK-----------ESNTTKGELQLKLDELQasdvsvkakkRLEQEKELLHSQntwlNTELKTKTDELL 284
Cdd:TIGR02169  375 EVDKEFAETRDELKdyrekleklkrEINELKRELDRLQEELQ----------RLSEELADLNAA----IAGIEAKINELE 440

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119611609   285 ALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 348
Cdd:TIGR02169  441 EEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
mukB PRK04863
chromosome partition protein MukB;
742-1111 1.94e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  742 EAKAALKQLQEIFENYKKEKAENEkiqnEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRR-----EITS 816
Cdd:PRK04863  359 ELEERLEEQNEVVEEADEQQEENE----ARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERakqlcGLPD 434

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  817 LHERN-QKLTATTQKQEQiinTMTQDLRGANEKLAVAEVRAENLKKEKEMLK-----LSEVRLSQQRESLLAEQRGQNLL 890
Cdd:PRK04863  435 LTADNaEDWLEEFQAKEQ---EATEELLSLEQKLSVAQAAHSQFEQAYQLVRkiageVSRSEAWDVARELLRRLREQRHL 511

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  891 LTNLQTIQGILersetetkqrlssqiekleheishlkkkleNEVEQRHTLTRNLDVQLLDTKRQLdtetNLHLNTKELLK 970
Cdd:PRK04863  512 AEQLQQLRMRL------------------------------SELEQRLRQQQRAERLLAEFCKRL----GKNLDDEDELE 557

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  971 NAQKEIATLKQHLSnmevqvasqssqrtgkgqpSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEEs 1050
Cdd:PRK04863  558 QLQEELEARLESLS-------------------ESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLRE- 617

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609 1051 lnkekQVTEEVrknievrlkESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL 1111
Cdd:PRK04863  618 -----QSGEEF---------EDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERL 664
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1724-1900 2.46e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 43.37  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1724 TTPASGERGIASTSDPPTAN-IKPTPVVSTPSKVTAAAMAGNKSTPRASIRPmvtpaTVTNPTTTPTATVMPTTQVESQE 1802
Cdd:pfam05109  535 TSPTLGKTSPTSAVTTPTPNaTSPTPAVTTPTPNATIPTLGKTSPTSAVTTP-----TPNATSPTVGETSPQANTTNHTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1803 AMQSEGPVEHVPVFGSTSG---------SVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHP-------QIEPAnq 1866
Cdd:pfam05109  610 GGTSSTPVVTSPPKNATSAvttgqhnitSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPtggenitQVTPA-- 687

                          170       180       190
                   ....*....|....*....|....*....|....
gi 119611609  1867 elSSNIVEVVQSSPVERPSTSTAVFGTVSATPSS 1900
Cdd:pfam05109  688 --STSTHHVSTSSPAPRPGTTSQASGPGNSSTST 719
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1446-1691 2.62e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 42.21  E-value: 2.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1446 LTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKA 1525
Cdd:COG1340     6 LSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1526 QQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAE-----------------TKSKSLESQVENLQKTLsEKETEARN 1588
Cdd:COG1340    86 KLNELREELDELRKELAELNKAGGSIDKLRKEIERLEwrqqtevlspeeekelvEKIKELEKELEKAKKAL-EKNEKLKE 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1589 LQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITE---KEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQ 1665
Cdd:COG1340   165 LRAELKELRKEAEEIHKKIKELAEEAQELHEEMIElykEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRK 244

                         250       260
                  ....*....|....*....|....*.
gi 119611609 1666 QKDELDVRITALKSQYEGRISRLERE 1691
Cdd:COG1340   245 ELKKLRKKQRALKREKEKEELEEKAE 270
DivIVA COG3599
Cell division septum initiation protein DivIVA, interacts with FtsZ and MinD [Cell cycle ...
 1005-1113 2.96e-03

Cell division septum initiation protein DivIVA, interacts with FtsZ and MinD [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442818 [Multi-domain]  Cd Length: 125  Bit Score: 39.84  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1005 NKEDVDDLVSQLRQTEEQVN----DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVrknievrlKESAEfqTQLE 1080
Cdd:COG3599    21 DEDEVDEFLDEVAEDYERLIrenkELKEKLEELEEELEEYRELEETLQKTLVVAQETAEEV--------KENAE--KEAE 90

                          90       100       110
                  ....*....|....*....|....*....|...
gi 119611609 1081 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKK 1113
Cdd:COG3599    91 LIIKEAELEAEKIIEEAQEKARKIVREIEELKR 123
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 127-400 3.28e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 3.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  127 EQQYFEIEKRlshsQERLVNE-TRECQSLRLELEKLNNQLKALTEKNKeleiaqdrniaiqsqfTRTKEELEAEKRDLIR 205
Cdd:PRK05771   27 ELGVVHIEDL----KEELSNErLRKLRSLLTKLSEALDKLRSYLPKLN----------------PLREEKKKVSVKSLEE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  206 TNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQ---ASDVSVKAKKRLE---------QEKELLHSQNTWLN 273
Cdd:PRK05771   87 LIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwgNFDLDLSLLLGFKyvsvfvgtvPEDKLEELKLESDV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  274 TELKTKTDE------LLALGREKGNEILELKCNLENKKEEVS---RLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQqa 344
Cdd:PRK05771  167 ENVEYISTDkgyvyvVVVVLKELSDEVEEELKKLGFERLELEeegTPSELIREIKEELEEIEKERESLLEELKELAKK-- 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609  345 smEEKFHneLNAHIKLSNLYKSAaddsEAKSNELT-------------RAVEELHKLLKEAGEANKAIQ 400
Cdd:PRK05771  245 --YLEEL--LALYEYLEIELERA----EALSKFLKtdktfaiegwvpeDRVKKLKELIDKATGGSAYVE 305
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
773-1243 3.37e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 42.72  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  773 EKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVA 852
Cdd:PRK02224  310 EAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  853 EVRAENLKKEKEMLKLSEVRLSQQRESLLaeqrgqnllltnlqtiqgilersetETKQRLSSQIEKLEHEIshlkKKLEN 932
Cdd:PRK02224  390 EEEIEELRERFGDAPVDLGNAEDFLEELR-------------------------EERDELREREAELEATL----RTARE 440

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  933 EVEQRHTLtrnLDVQLLDTKRQlDTETNLHLNTkelLKNAQKEIATLKQHLSNMEVQVASqssqrtgkgqpsnKEDVDDL 1012
Cdd:PRK02224  441 RVEEAEAL---LEAGKCPECGQ-PVEGSPHVET---IEEDRERVEELEAELEDLEEEVEE-------------VEERLER 500

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1013 VSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVtsleeslnkekqvtEEVRKNIEVRLKESAEFQTQLEKKlMEVEKEKQE 1092
Cdd:PRK02224  501 AEDLVEAEDRIERLEERREDLEELIAERRETI--------------EEKRERAEELRERAAELEAEAEEK-REAAAEAEE 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1093 LQDDKRRAIESMEQQLSELKKTLSSVQN--EVQEALQRASTALSN-----EQQARRDCQEQAKIAVEAQNKYERELMLHA 1165
Cdd:PRK02224  566 EAEEAREEVAELNSKLAELKERIESLERirTLLAAIADAEDEIERlrekrEALAELNDERRERLAEKRERKRELEAEFDE 645

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1166 ADVEALQAAKEQVSK-MASVRQHLEETTQKAESQLLECKASWEERERM--LKDEVSKCVCRCEDLEKqnrlLHDQIEKLS 1242
Cdd:PRK02224  646 ARIEEAREDKERAEEyLEQVEEKLDELREERDDLQAEIGAVENELEELeeLRERREALENRVEALEA----LYDEAEELE 721


                  .
gi 119611609 1243 D 1243
Cdd:PRK02224  722 S 722
PRK12704 PRK12704
phosphodiesterase; Provisional
 1510-1682 3.37e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1510 KKIGrryKTQYEELKAQQDKVMEtSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKEteaRNL 1589
Cdd:PRK12704   26 KKIA---EAKIKEAEEEAKRILE-EAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKE---ENL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1590 QEQtvqlQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGvkdqLTKenEELKQRngALDQQKDE 1669
Cdd:PRK12704   99 DRK----LELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISG----LTA--EEAKEI--LLEKVEEE 166

                         170
                  ....*....|...
gi 119611609 1670 LDVRITALKSQYE 1682
Cdd:PRK12704  167 ARHEAAVLIKEIE 179
PRK05431 PRK05431
seryl-tRNA synthetase; Provisional
 1477-1579 3.67e-03

seryl-tRNA synthetase; Provisional


Pssm-ID: 235461 [Multi-domain]  Cd Length: 425  Bit Score: 42.36  E-value: 3.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1477 DLNKVRTEKETIQKDLDAK--IIDIQEKVKTITQVKKIgrryKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL 1554
Cdd:PRK05431    3 DIKLIRENPEAVKEALAKRgfPLDVDELLELDEERREL----QTELEELQAERNALSKEIGQAKRKGEDAEALIAEVKEL 78

                          90       100
                  ....*....|....*....|....*
gi 119611609 1555 KETLNQAETKSKSLESQVENLQKTL 1579
Cdd:PRK05431   79 KEEIKALEAELDELEAELEELLLRI 103
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 490-677 3.90e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  490 ENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERD----NRRME 565
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEiaelRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  566 IQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSsevISQHLVSYRN--IEELQQQNQRLLVALRELgetreree 643
Cdd:COG4942   101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ---YLKYLAPARReqAEELRADLAELAALRAEL-------- 169

                         170       180       190
                  ....*....|....*....|....*....|....
gi 119611609  644 qETTSSKITELQLKLESALTELEQLRKSRQHQMQ 677
Cdd:COG4942   170 -EAERAELEALLAELEEERAALEALKAERQKLLA 202
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1715-1952 3.93e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.25  E-value: 3.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1715 EQQRQITLKTTPASGErgiaSTSDPPTANIKPTPVVSTPSKV---TAAAMAG----NKSTPRASIRPMVTPATVTNPTTT 1787
Cdd:pfam17823   89 EHTPHGTDLSEPATRE----GAADGAASRALAAAASSSPSSAaqsLPAAIAAlpseAFSAPRAAACRANASAAPRAAIAA 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1788 PTA----TVMPTTQVESQEAMQSEGPVEHVPVFGSTS---------GSVRSTSPNVQPSISQ-----PILTVQQQTQATA 1849
Cdd:pfam17823  165 ASAphaaSPAPRTAASSTTAASSTTAASSAPTTAASSapatltparGISTAATATGHPAAGTalaavGNSSPAAGTVTAA 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1850 FVQPTQQSHPQIEPANQELSSNIVEVVQSSPVER---PSTSTAVfGTVSATPSSSLpkrtREEEEDSTIEAS-DQVSDDT 1925
Cdd:pfam17823  245 VGTVTPAALATLAAAAGTVASAAGTINMGDPHARrlsPAKHMPS-DTMARNPAAPM----GAQAQGPIIQVStDQPVHNT 319

                          250       260
                   ....*....|....*....|....*..
gi 119611609  1926 VEMPLPKKLKSVTPVGTEEEVMAEEST 1952
Cdd:pfam17823  320 AGEPTPSPSNTTLEPNTPKSVASTNLA 346
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1228-1693 4.08e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 42.25  E-value: 4.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1228 EKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLE 1307
Cdd:COG5185   104 NSLIKLPNYEWSADILISLLYLYKSEIVALKDELIKVEKLDEIADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIFG 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1308 RELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANA 1387
Cdd:COG5185   184 LTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEKLVEQNT 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1388 ELSEKSGMLQAE------------KKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKA 1455
Cdd:COG5185   264 DLRLEKLGENAEsskrlnenannlIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTA 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1456 EIARSNASLTNNQNLIQSLKE------DLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGrrYKTQYEELKAQQDK 1529
Cdd:COG5185   344 EIEQGQESLTENLEAIKEEIEnivgevELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEI--LATLEDTLKAADRQ 421

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1530 VMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQ--VENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDL 1607
Cdd:COG5185   422 IEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSrlEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATL 501

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1608 QDRTT----QEEQLRQQITEKEEKTRKAivAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEG 1683
Cdd:COG5185   502 EKLRAklerQLEGVRSKLDQVAESLKDF--MRARGYAHILALENLIPASELIQASNAKTDGQAANLRTAVIDELTQYLST 579

                         490
                  ....*....|
gi 119611609 1684 RISRLERELR 1693
Cdd:COG5185   580 IESQQAREDP 589
46 PHA02562
endonuclease subunit; Provisional
 83-246 4.09e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 4.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   83 QVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESE-----QQYFEIEKRLSHSQERLVNetrecqslrle 157
Cdd:PHA02562  242 ELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVcptctQQISEGPDRITKIKDKLKE----------- 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  158 lekLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTN----------ERLSQELEYLTEDVKRLNEK 227
Cdd:PHA02562  311 ---LQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVdkakkvkaaiEELQAEFVDNAEELAKLQDE 387

                         170
                  ....*....|....*....
gi 119611609  228 LKESNTTKGELQLKLDELQ 246
Cdd:PHA02562  388 LDKIVKTKSELVKEKYHRG 406
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1037-1185 4.34e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.51  E-value: 4.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1037 VEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKEsaefqtqLEKKLMEVEKEKQELQDDKrraiesmEQQLSELKKTLS 1116
Cdd:PRK00409  504 IEEAKKLIGEDKEKLNELIASLEELERELEQKAEE-------AEALLKEAEKLKEELEEKK-------EKLQEEEDKLLE 569

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119611609 1117 SVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVR 1185
Cdd:PRK00409  570 EAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
PRK01156 PRK01156
chromosome segregation protein; Provisional
 747-1119 4.38e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.58  E-value: 4.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  747 LKQLQEIFENYKKEK-------AENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHE 819
Cdd:PRK01156  372 IESLKKKIEEYSKNIermsafiSEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNG 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  820 RNQ----KLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQResllaeqrgqnllltnlq 895
Cdd:PRK01156  452 QSVcpvcGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEE------------------ 513

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  896 tiqgiLERSETETKQ--RLSSQIEKLEHEISHLKKKlENEVEQRHTLTRNLDVQLLDTKRQ-----LDTETNLHLNTKEL 968
Cdd:PRK01156  514 -----INKSINEYNKieSARADLEDIKIKINELKDK-HDKYEEIKNRYKSLKLEDLDSKRTswlnaLAVISLIDIETNRS 587

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  969 LKN-AQKEIATLKQHLSNMEVQVASQSSQrtgkgQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSL 1047
Cdd:PRK01156  588 RSNeIKKQLNDLESRLQEIEIGFPDDKSY-----IDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEI 662

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119611609 1048 EESLNKEKQVTEEVrKNIEVRLKESaefQTQLEKKLMEvEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQ 1119
Cdd:PRK01156  663 DSIIPDLKEITSRI-NDIEDNLKKS---RKALDDAKAN-RARLESTIEILRTRINELSDRINDINETLESMK 729
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 81-429 4.40e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 4.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    81 LQQVLERTELNK--LPKSVQNkLEKFLADQQSEIDGL---KGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLR 155
Cdd:pfam01576  361 LTEQLEQAKRNKanLEKAKQA-LESENAELQAELRTLqqaKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQ 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   156 LELEKLNNQLKALTEKNKELeiaQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQeleyLTEDVKRLNEKLKESNTTK 235
Cdd:pfam01576  440 SELESVSSLLNEAEGKNIKL---SKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ----LEDERNSLQEQLEEEEEAK 512

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   236 GELQLKLDELQASdvSVKAKKRLEQEKELLhsqntwlntelktktdELLALGREKgneileLKCNLENKKEEVSRLEEQM 315
Cdd:pfam01576  513 RNVERQLSTLQAQ--LSDMKKKLEEDAGTL----------------EALEEGKKR------LQRELEALTQQLEEKAAAY 568

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   316 NGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK---FHNELNAHIKLSNLYKSAADDSEAKSNE-------LTRAVEEL 385
Cdd:pfam01576  569 DKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKqkkFDQMLAEEKAISARYAEERDRAEAEAREketralsLARALEEA 648

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 119611609   386 HKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM--LEKIGR-LEKELE 429
Cdd:pfam01576  649 LEAKEELERTNKQLRAEMEDLVSSKDDVGKNVheLERSKRaLEQQVE 695
WEMBL pfam05701
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ...
 1280-1703 4.44e-03

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".


Pssm-ID: 461718 [Multi-domain]  Cd Length: 562  Bit Score: 42.32  E-value: 4.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1280 REKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAERekvqvtaktmAQHEELMKKteTMNVVMetnkMLREEKE 1359
Cdd:pfam05701  159 SERDIAIKRAEEAVSASKEIEKTVEELTIELIATKESLESAH----------AAHLEAEEH--RIGAAL----AREQDKL 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1360 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQ---------AEKKLLEEDVKRWKARNQHLVSQQK-DPDTEEY 1429
Cdd:pfam05701  223 NWEKELKQAEEELQRLNQQLLSAKDLKSKLETASALLLdlkaelaayMESKLKEEADGEGNEKKTSTSIQAAlASAKKEL 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1430 RKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNL-------IQSLKEDLNKVRTEKETIQkdldAKIIDIQEK 1502
Cdd:pfam05701  303 EEVKANIEKAKDEVNCLRVAAASLRSELEKEKAELASLRQRegmasiaVSSLEAELNRTKSEIALVQ----AKEKEAREK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1503 VKTITQvkkigrryKTQYEELKAQQDKVMETSAQssgdhqeqhvsvQEMQELKETLNQAETKSKSLESQVENLQK-TLSE 1581
Cdd:pfam05701  379 MVELPK--------QLQQAAQEAEEAKSLAQAAR------------EELRKAKEEAEQAKAAASTVESRLEAVLKeIEAA 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1582 KETEARNLQEQTVQLQSELSRLRQDLQDR------TTQE-EQLRQQITEKEEKTRKAIVAAKSKIAHlagVKDQLTKENE 1654
Cdd:pfam05701  439 KASEKLALAAIKALQESESSAESTNQEDSprgvtlSLEEyYELSKRAHEAEELANKRVAEAVSQIEE---AKESELRSLE 515

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 119611609  1655 ELKQRNGALDQQKDELDVRITALKSQYEGRISrLERELREHQERHlEQR 1703
Cdd:pfam05701  516 KLEEVNREMEERKEALKIALEKAEKAKEGKLA-AEQELRKWRAEH-EQR 562
PRK11637 PRK11637
AmiB activator; Provisional
 973-1183 4.57e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 41.99  E-value: 4.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  973 QKEIATLKQHLSNMEVQVASQSSQRTG-KGQPSNKEDVDDLVS-QLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEES 1050
Cdd:PRK11637   46 RDQLKSIQQDIAAKEKSVRQQQQQRASlLAQLKKQEEAISQASrKLRETQNTLNQLNKQIDELNASIAKLEQQQAAQERL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1051 LNK---------------------EKQVTE----------EVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRR 1099
Cdd:PRK11637  126 LAAqldaafrqgehtglqlilsgeESQRGErilayfgylnQARQETIAELKQTREELAAQKAELEEKQSQQKTLLYEQQA 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1100 AIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARrdcQEQAKIAVEAQNKYERElmlhAADVEALQAAKEQVS 1179
Cdd:PRK11637  206 QQQKLEQARNERKKTLTGLESSLQKDQQQLSELRANESRLR---DSIARAEREAKARAERE----AREAARVRDKQKQAK 278


                  ....
gi 119611609 1180 KMAS 1183
Cdd:PRK11637  279 RKGS 282
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1274-1588 4.61e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.37  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1274 ILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSlNAEREKVQVTAKTMAQhEELMKKTETMNVVMETNKM 1353
Cdd:COG5022   848 IQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKID-VKSISSLKLVNLELES-EIIELKKSLSSDLIENLEF 925

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1354 LREEKERLEQDLQQMQAKVRKL----ELDIL-PLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPdtEE 1428
Cdd:COG5022   926 KTELIARLKKLLNNIDLEEGPSieyvKLPELnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKEL--AE 1003

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1429 YRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLiQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQ 1508
Cdd:COG5022  1004 LSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSIL-KPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQ 1082

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1509 VKKIGRrykTQYEELKAQQDKVMETSAQSSGD------HQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEK 1582
Cdd:COG5022  1083 LYQLES---TENLLKTINVKDLEVTNRNLVKPanvlqfIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGL 1159


                  ....*.
gi 119611609 1583 ETEARN 1588
Cdd:COG5022  1160 FWEANL 1165
xseA TIGR00237
exodeoxyribonuclease VII, large subunit; This family consist of exodeoxyribonuclease VII, ...
 61-168 5.48e-03

exodeoxyribonuclease VII, large subunit; This family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits. [DNA metabolism, Degradation of DNA]


Pssm-ID: 272979 [Multi-domain]  Cd Length: 389  Bit Score: 41.65  E-value: 5.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609    61 ASTPSAAAT-GVPgptDMAAVLQQVLERTElnKLPKSVQNKLEkflaDQQSEIDGLKGRHEKF----KVESEQQYFE-IE 134
Cdd:TIGR00237  244 APTPTAAAElAVP---DRAELLQRLDQLRE--RLRRALQRRLE----RERQRLDRLRSRLVLAsperLLERQRQRLDrLE 314

                           90       100       110
                   ....*....|....*....|....*....|....
gi 119611609   135 KRLSHSQERLVNETREcqslrlELEKLNNQLKAL 168
Cdd:TIGR00237  315 QRLKRALRRRLERKRQ------RLELLAARLEAL 342
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 177-450 5.53e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 5.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   177 IAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELqlKLDELQASDvsvkakk 256
Cdd:pfam12128  206 LEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGY--KSDETLIAS------- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   257 RLEQEKELLHSqntwLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQmnglktsneHLQKHVEDLltkl 336
Cdd:pfam12128  277 RQEERQETSAE----LNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQ---------HGAFLDADI---- 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   337 kEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSN--------ELTRAVEELHKLLKEAGEA----NKAIQDHLL 404
Cdd:pfam12128  340 -ETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNrrrskikeQNNRDIAGIKDKLAKIREArdrqLAVAEDDLQ 418

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 119611609   405 EVEQS-KDQMEKEMLE-KIG--RLEKELENANDLLSatkrkGAILSEEEL 450
Cdd:pfam12128  419 ALESElREQLEAGKLEfNEEeyRLKSRLGELKLRLN-----QATATPELL 463
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 869-1448 5.73e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 42.04  E-value: 5.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   869 SEVRLSQQRESL----LAEQRGQNLLLTNLQTIQGILERsETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNL 944
Cdd:pfam05557    7 SKARLSQLQNEKkqmeLEHKRARIELEKKASALKRQLDR-ESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   945 DVQLLDTKRQLDTETNLHlntkELLKNAQKEIATLKQHLSNMEVQVASQSSQrtgkgqpsnKEDVDDLVSQLRQTEEQVN 1024
Cdd:pfam05557   86 EALNKKLNEKESQLADAR----EVISCLKNELSELRRQIQRAELELQSTNSE---------LEELQERLDLLKAKASEAE 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1025 DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVrKNIEVRLKESAEFQTQLEKkLMEVEKEKQELQDDKrraiESM 1104
Cdd:pfam05557  153 QLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEIV-KNSKSELARIPELEKELER-LREHNKHLNENIENK----LLL 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1105 EQQLSELKKTLSSvQNEVQEALqrASTALSNEQQARRdcqeqakiaveaQNKYERELMLHAADVEALQAAKEQVSKMASV 1184
Cdd:pfam05557  227 KEEVEDLKRKLER-EEKYREEA--ATLELEKEKLEQE------------LQSWVKLAQDTGLNLRSPEDLSRRIEQLQQR 291

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1185 RQHLEETTQKAESQLLECKASweerERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKE---------GVQG 1255
Cdd:pfam05557  292 EIVLKEENSSLTSSARQLEKA----RRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKErdgyraileSYDK 367

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1256 PLNVSLSEEGKSQ--EQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERelqelqdSLNAEREKVQVTAKTMAQ 1333
Cdd:pfam05557  368 ELTMSNYSPQLLEriEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLER-------ELQALRQQESLADPSYSK 440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1334 HE--ELMKKTETMNVvmeTNKMLREEKERLE-----QDLQQM--QAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE 1404
Cdd:pfam05557  441 EEvdSLRRKLETLEL---ERQRLREQKNELEmelerRCLQGDydPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLK 517

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 119611609  1405 EDVKRWKARN---QHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTE 1448
Cdd:pfam05557  518 RLLKKLEDDLeqvLRLPETTSTMNFKEVLDLRKELESAELKNQRLKE 564
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
208-391 6.04e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 6.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  208 ERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKAKKRLEQekellhsqntwLNTELKTKTDELLALg 287
Cdd:COG4913   613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS-----------AEREIAELEAELERL- 680

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  288 rEKGN-EILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF----HNELNAHIKLSN 362
Cdd:COG4913   681 -DASSdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLArlelRALLEERFAAAL 759

                         170       180
                  ....*....|....*....|....*....
gi 119611609  363 LYKSAADDSEAKSNELTRAVEELHKLLKE 391
Cdd:COG4913   760 GDAVERELRENLEERIDALRARLNRAEEE 788
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 927-1139 6.33e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 6.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  927 KKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQ---------SSQR 997
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERreelgerarALYR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  998 TGKGQPS-----NKEDVDDLVSQ---LRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRL 1069
Cdd:COG3883    98 SGGSVSYldvllGSESFSDFLDRlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1070 KESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQA 1139
Cdd:COG3883   178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 745-1111 6.92e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 6.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  745 AALKQlQEIFENYKKEKAE-NEK--IQNEQLEKLQEQVTDLRSQNT-------KISTQLDFASKRYEMLQDNVEGYRREI 814
Cdd:COG3096   341 TALRQ-QEKIERYQEDLEElTERleEQEEVVEEAAEQLAEAEARLEaaeeevdSLKSQLADYQQALDVQQTRAIQYQQAV 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  815 TSLhERNQKLT--------------ATTQKQEQIIntmTQDLRGANEKLAVAEVRAENLKKEKEMLKL--SEVRLS---Q 875
Cdd:COG3096   420 QAL-EKARALCglpdltpenaedylAAFRAKEQQA---TEEVLELEQKLSVADAARRQFEKAYELVCKiaGEVERSqawQ 495

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  876 QRESLLAEQRGQNLLLTNLQTIQGILerseTETKQRLSSQiekleheisHLKKKLENEVEQRHtltrnldvqlldtKRQL 955
Cdd:COG3096   496 TARELLRRYRSQQALAQRLQQLRAQL----AELEQRLRQQ---------QNAERLLEEFCQRI-------------GQQL 549

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  956 DTETNLhlntKELLKNAQKEIATLKQhlsnmevQVASQSSQRtgkgqpsnkedvddlvSQLRQTEEQVNDLKERLKTSTS 1035
Cdd:COG3096   550 DAAEEL----EELLAELEAQLEELEE-------QAAEAVEQR----------------SELRQQLEQLRARIKELAARAP 602

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119611609 1036 NVEQYQAMVTSLEEslnkekQVTEEVRKNIEVrlkeSAEFQTQLEkKLMEVEKEKQELQDDKrraiESMEQQLSEL 1111
Cdd:COG3096   603 AWLAAQDALERLRE------QSGEALADSQEV----TAAMQQLLE-REREATVERDELAARK----QALESQIERL 663
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 904-1128 6.94e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 41.34  E-value: 6.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   904 SETETKQRLSSqiekLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDtetnlhlntkellkNAQKEIATLKQHL 983
Cdd:pfam15905  146 SEDGTQKKMSS----LSMELMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLE--------------HSKGKVAQLEEKL 207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   984 SNMEVQVASQSSQrtgkgqpsnkedvddlvsqlrqTEEQVNDLKErLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRK 1063
Cdd:pfam15905  208 VSTEKEKIEEKSE----------------------TEKLLEYITE-LSCVSEQVEKYKLDIAQLEELLKEKNDEIESLKQ 264

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119611609  1064 NIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQR 1128
Cdd:pfam15905  265 SLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLNAELEELKEKLTLEEQEHQKLQQK 329
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1413-1719 7.31e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.42  E-value: 7.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1413 RNQHLVSQQKDPDTEEYRKllsEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN---NQNLIQSLKEDLNKVRTEKETIQ 1489
Cdd:pfam07888   48 QAQEAANRQREKEKERYKR---DREQWERQRRELESRVAELKEELRQSREKHEEleeKYKELSASSEELSEEKDALLAQR 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1490 KDLDAKIIDIQEKVKTITQvkkigrryktQYEELKAQQDKVMETSAQSSGDHQEQHvsvQEMQELKETLNQAETKSKSLE 1569
Cdd:pfam07888  125 AAHEARIRELEEDIKTLTQ----------RVLERETELERMKERAKKAGAQRKEEE---AERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1570 SQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQdlqdRTTQEEQLRQQIT---EKEEKTRKAIVAAKSKIAHLAGVK 1646
Cdd:pfam07888  192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHR----KEAENEALLEELRslqERLNASERKVEGLGEELSSMAAQR 267

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119611609  1647 DQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQ 1719
Cdd:pfam07888  268 DRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERME 340
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
325-542 7.40e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 7.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  325 LQKHVEDLLTKLKEAKEQQASMEEKfhneLNAHIKLSNlYKSAADDSEAKSNELTRAVEELHKLLKEAGEAnKAIQDHLL 404
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQER----REALQRLAE-YSWDEIDVASAEREIAELEAELERLDASSDDL-AALEEQLE 695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  405 EVEQSKDQMEKE---MLEKIGRLEKELENANDLLSAtkrkgailseeelaamsptaaavakivkpgmkLTELYNAYVETQ 481
Cdd:COG4913   696 ELEAELEELEEEldeLKGEIGRLEKELEQAEEELDE--------------------------------LQDRLEAAEDLA 743

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609  482 DQLLLEKLENKRINKYLDEIVKEVEakapilKRQREEYERAQKAVASLSVKLEQAMKEIQR 542
Cdd:COG4913   744 RLELRALLEERFAAALGDAVERELR------ENLEERIDALRARLNRAEEELERAMRAFNR 798
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1014-1257 7.45e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 7.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1014 SQLRQTEEQVNDLKERLKTSTSNVEQYQamvtsleeslnKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQEL 1093
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALK-----------KEEKALLKQLAALERRIAALARRIRALEQELAALEAELAEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1094 QDDKRRAIESMEQQLSELKKTLSSVQ-NEVQEALQRASTALSNEQQARRdcQEQAKIAVEAQNKYERELmlhAADVEALQ 1172
Cdd:COG4942    89 EKEIAELRAELEAQKEELAELLRALYrLGRQPPLALLLSPEDFLDAVRR--LQYLKYLAPARREQAEEL---RADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1173 AAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEG 1252
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                  ....*
gi 119611609 1253 VQGPL 1257
Cdd:COG4942   244 PAAGF 248
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1566-1698 8.39e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 8.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1566 KSLESQVENLQKTLSEK----ETEARNLQEQTVQlqSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAivaaksKIAH 1641
Cdd:COG2433   346 DAYKNKFERVEKKVPPDvdrdEVKARVIRGLSIE--EALEELIEKELPEEEPEAEREKEHEERELTEEEE------EIRR 417

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1642 LAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQY-------------EGRISRLERELREHQER 1698
Cdd:COG2433   418 LEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEErreirkdreisrlDREIERLERELEEERER 487
PRK12704 PRK12704
phosphodiesterase; Provisional
 1049-1182 8.83e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 8.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1049 ESLNKEK--QVTEEVRK-----NIEVRLKESaEFQtQLEKKLMEVE---KEKQELQDDKRRAIESMEQQLSELKKTLSSV 1118
Cdd:PRK12704   52 EAIKKEAllEAKEEIHKlrnefEKELRERRN-ELQ-KLEKRLLQKEenlDRKLELLEKREEELEKKEKELEQKQQELEKK 129

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119611609 1119 QNEVQEALQRASTALsnEQQARRDcQEQAK--IAVEAQNKYERELMLHAADVEalQAAKEQVSKMA 1182
Cdd:PRK12704  130 EEELEELIEEQLQEL--ERISGLT-AEEAKeiLLEKVEEEARHEAAVLIKEIE--EEAKEEADKKA 190
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1714-1900 8.85e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.10  E-value: 8.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1714 PEQQRQITLKTTPA-SGERGIASTSDPPTANikPTPVVSTPSKVTAAAmagNKSTPRASIRPMvtPATVTNPTTTPTATV 1792
Cdd:pfam17823  275 PHARRLSPAKHMPSdTMARNPAAPMGAQAQG--PIIQVSTDQPVHNTA---GEPTPSPSNTTL--EPNTPKSVASTNLAV 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609  1793 MPTTQVESQEAMQSEGPVEHVpvfgSTSGSVRSTSPNVQPSisqPILTVqQQTQATAFVQPTQQSHPQIEPANQelssni 1872
Cdd:pfam17823  348 VTTTKAQAKEPSASPVPVLHT----SMIPEVEATSPTTQPS---PLLPT-QGAAGPGILLAPEQVATEATAGTA------ 413

                          170       180
                   ....*....|....*....|....*...
gi 119611609  1873 vevvQSSPVERPSTSTAVFGTVSATPSS 1900
Cdd:pfam17823  414 ----SAGPTPRSSGDPKTLAMASCQLST 437
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1569-1708 9.14e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.35  E-value: 9.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1569 ESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ-EEQLRQQITEKEEKTRKAIVAAKSKIahlagvkD 1647
Cdd:PRK00409  515 KEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKlQEEEDKLLEEAEKEAQQAIKEAKKEA-------D 587

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119611609 1648 QLTKENEELKQRNGALDQQKDELDVRiTALKSQYEgrisrlerELREHQERHLEQRDEPQE 1708
Cdd:PRK00409  588 EIIKELRQLQKGGYASVKAHELIEAR-KRLNKANE--------KKEKKKKKQKEKQEELKV 639
PRK11281 PRK11281
mechanosensitive channel MscK;
1420-1620 9.27e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 9.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1420 QQKDPDTEEyrKLLSEKEVHT----KRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKED------------------ 1477
Cdd:PRK11281   50 KQKLLEAED--KLVQQDLEQTlallDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDndeetretlstlslrqle 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1478 --LNKVRTEKETIQKDL---DAKIIDIQ---EKVKTI-----TQVKKIGRRYK-----------TQYEELKAQQDKVMet 1533
Cdd:PRK11281  128 srLAQTLDQLQNAQNDLaeyNSQLVSLQtqpERAQAAlyansQRLQQIRNLLKggkvggkalrpSQRVLLQAEQALLN-- 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1534 sAQSSGDHQEQHVSVQeMQEL-KETLNQAETKSKSLESQVENLQKTLSEKEteaRNLQEQTVQ----------------L 1596
Cdd:PRK11281  206 -AQNDLQRKSLEGNTQ-LQDLlQKQRDYLTARIQRLEHQLQLLQEAINSKR---LTLSEKTVQeaqsqdeaariqanplV 280

                         250       260
                  ....*....|....*....|....*..
gi 119611609 1597 QSELS---RLRQDLQDRTTQEEQLRQQ 1620
Cdd:PRK11281  281 AQELEinlQLSQRLLKATEKLNTLTQQ 307
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
1015-1148 9.28e-03

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 40.99  E-value: 9.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1015 QLRQTEEQVNDLKERLKTSTSNVEQYQamvtsleeslNKEKQVTEEvrKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQ 1094
Cdd:COG3524   178 AVRFAEEEVERAEERLRDAREALLAFR----------NRNGILDPE--ATAEALLQLIATLEGQLAELEAELAALRSYLS 245

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119611609 1095 DDK------RRAIESMEQQLSELKKTLSSV----------------QNEVQEALQRASTALSNEQQARRDCQEQAK 1148
Cdd:COG3524   246 PNSpqvrqlRRRIAALEKQIAAERARLTGAsggdslasllaeyerlELEREFAEKAYTSALAALEQARIEAARQQR 321
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1261-1636 9.59e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 9.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1261 LSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELqdSLNAEREKVQvtaktmAQHEELMKK 1340
Cdd:COG4717    76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALE------AELAELPER 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1341 TETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEAN-AELSEKSGMLQAEKKLLEEDVKRWKARNQHLVS 1419
Cdd:COG4717   148 LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1420 Q-----QKDPDTEEYRKLLSEK----------------------------------EVHTKRIQQLTEEIGRLKAEIARS 1460
Cdd:COG4717   228 EleqleNELEAAALEERLKEARlllliaaallallglggsllsliltiagvlflvlGLLALLFLLLAREKASLGKEAEEL 307

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1461 NASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQyeELKAQQDKVMETSAQSSGD 1540
Cdd:COG4717   308 QALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE--ELEQEIAALLAEAGVEDEE 385

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1541 --------HQEQHVSVQEMQELKETLNQAETKSKSLESQV--ENLQKTLSEKETEARNLQEQTVQLQSELSRLRQ----- 1605
Cdd:COG4717   386 elraaleqAEEYQELKEELEELEEQLEELLGELEELLEALdeEELEEELEELEEELEELEEELEELREELAELEAeleql 465

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 119611609 1606 ----DLQDRTTQEEQLRQQITEKEEKTRKAIVAAK 1636
Cdd:COG4717   466 eedgELAELLQELEELKAELRELAEEWAALKLALE 500
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 220-942 9.59e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 9.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   220 DVKRLNEKLKESNTTKGELQLKLDELQASD--VSVKAKKRLEQEKELLHSQNT---WLN--TELKTKTDELLALGREKGN 292
Cdd:pfam05483  100 ELKQKENKLQENRKIIEAQRKAIQELQFENekVSLKLEEEIQENKDLIKENNAtrhLCNllKETCARSAEKTKKYEYERE 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   293 EILELKCNLENKKEEVSRLEEQMNgLKTSNEHLQKHVedlltKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSE 372
Cdd:pfam05483  180 ETRQVYMDLNNNIEKMILAFEELR-VQAENARLEMHF-----KLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKE 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   373 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM------LEKIGRLEKELEnaNDLLSATKRKGAILS 446
Cdd:pfam05483  254 NKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELedikmsLQRSMSTQKALE--EDLQIATKTICQLTE 331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   447 EEELAAMSPTAAAVAKivkpGMKLTELyNAYVETQDQLLleKLENKRINKYLDEIvkevEAKAPILKRQREEYERAQKAV 526
Cdd:pfam05483  332 EKEAQMEELNKAKAAH----SFVVTEF-EATTCSLEELL--RTEQQRLEKNEDQL----KIITMELQKKSSELEEMTKFK 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   527 ASLSVKLEQaMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSE 606
Cdd:pfam05483  401 NNKEVELEE-LKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTE 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   607 VISQHLvsyRNIeELQQQNQRLLVALRELgetrereeqettSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQR 686
Cdd:pfam05483  480 LEKEKL---KNI-ELTAHCDKLLLENKEL------------TQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE 543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   687 DMYRillsqttgvaiplhaSSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEkAENek 766
Cdd:pfam05483  544 MNLR---------------DELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQ-IEN-- 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   767 iQNEQLEKLQEQVTDLRSQNTKISTQLDFaskrYEMLQDNVEgyrREITSLHERNQKLTATTQKQEQIINTMTQDLRGAN 846
Cdd:pfam05483  606 -KNKNIEELHQENKALKKKGSAENKQLNA----YEIKVNKLE---LELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEV 677

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609   847 EKLAVAEVRAENLKKE---------KEMLKLSEVRLSQQREslLAEQRGQNLLLTNLQtiqgilERSETETKQRLSSQIE 917
Cdd:pfam05483  678 EKAKAIADEAVKLQKEidkrcqhkiAEMVALMEKHKHQYDK--IIEERDSELGLYKNK------EQEQSSAKAALEIELS 749

                          730       740
                   ....*....|....*....|....*
gi 119611609   918 KLEHEISHLKKKLENEVEQRHTLTR 942
Cdd:pfam05483  750 NIKAELLSLKKQLEIEKEEKEKLKM 774
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1442-1727 9.86e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 9.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1442 RIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYE 1521
Cdd:COG4372    39 ELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELE 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1522 ELKAQQDKVMETSAQSSgdhqeqhvsvQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQtvQLQSELS 1601
Cdd:COG4372   119 ELQKERQDLEQQRKQLE----------AQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEA--EAEQALD 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119611609 1602 RLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQY 1681
Cdd:COG4372   187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 119611609 1682 EGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPA 1727
Cdd:COG4372   267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGA 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH