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hepatocyte growth factor (hepapoietin A; scatter factor), isoform CRA_a [Homo sapiens]
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
Tryp_SPc | smart00020 | Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens ... |
494-716 | 5.85e-67 | ||||
Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues. : Pssm-ID: 214473 Cd Length: 229 Bit Score: 220.24 E-value: 5.85e-67
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
210-290 | 6.00e-41 | ||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. : Pssm-ID: 214527 Cd Length: 83 Bit Score: 144.07 E-value: 6.00e-41
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
126-208 | 1.45e-38 | ||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. : Pssm-ID: 214527 Cd Length: 83 Bit Score: 137.52 E-value: 1.45e-38
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
304-384 | 1.61e-37 | ||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. : Pssm-ID: 214527 Cd Length: 83 Bit Score: 134.44 E-value: 1.61e-37
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
388-470 | 4.25e-34 | ||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. : Pssm-ID: 238056 Cd Length: 83 Bit Score: 124.80 E-value: 4.25e-34
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PAN_APPLE | cd00129 | PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth ... |
39-122 | 1.30e-27 | ||||
PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech anti-platelet proteins. Common structural features include two disulfide bonds that link the alpha-helix to the central region of the protein. PAN domains have significant functional versatility, fulfilling diverse biological functions by mediating protein-protein or protein-carbohydrate interactions. : Pssm-ID: 238074 Cd Length: 80 Bit Score: 106.24 E-value: 1.30e-27
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Name | Accession | Description | Interval | E-value | |||||
Tryp_SPc | smart00020 | Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens ... |
494-716 | 5.85e-67 | |||||
Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues. Pssm-ID: 214473 Cd Length: 229 Bit Score: 220.24 E-value: 5.85e-67
|
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Tryp_SPc | cd00190 | Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens ... |
495-719 | 4.55e-66 | |||||
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues. Pssm-ID: 238113 [Multi-domain] Cd Length: 232 Bit Score: 218.30 E-value: 4.55e-66
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Trypsin | pfam00089 | Trypsin; |
495-716 | 9.22e-56 | |||||
Trypsin; Pssm-ID: 459667 [Multi-domain] Cd Length: 219 Bit Score: 189.96 E-value: 9.22e-56
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
210-290 | 6.00e-41 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 144.07 E-value: 6.00e-41
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
211-288 | 5.00e-39 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 138.59 E-value: 5.00e-39
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
126-208 | 1.45e-38 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 137.52 E-value: 1.45e-38
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
208-289 | 5.18e-38 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 135.97 E-value: 5.18e-38
|
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COG5640 | COG5640 | Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, ... |
488-720 | 5.69e-38 | |||||
Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 444365 [Multi-domain] Cd Length: 262 Bit Score: 142.10 E-value: 5.69e-38
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
126-207 | 7.03e-38 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 135.58 E-value: 7.03e-38
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
304-384 | 1.61e-37 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 134.44 E-value: 1.61e-37
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
305-383 | 3.40e-37 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 133.59 E-value: 3.40e-37
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
302-384 | 7.91e-37 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 132.50 E-value: 7.91e-37
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
388-470 | 4.25e-34 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 124.80 E-value: 4.25e-34
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
128-206 | 1.07e-33 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 123.57 E-value: 1.07e-33
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
389-471 | 1.39e-33 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 123.27 E-value: 1.39e-33
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
391-469 | 1.19e-31 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 117.79 E-value: 1.19e-31
|
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PAN_APPLE | cd00129 | PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth ... |
39-122 | 1.30e-27 | |||||
PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech anti-platelet proteins. Common structural features include two disulfide bonds that link the alpha-helix to the central region of the protein. PAN domains have significant functional versatility, fulfilling diverse biological functions by mediating protein-protein or protein-carbohydrate interactions. Pssm-ID: 238074 Cd Length: 80 Bit Score: 106.24 E-value: 1.30e-27
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PAN_AP | smart00473 | divergent subfamily of APPLE domains; Apple-like domains present in Plasminogen, C. elegans ... |
37-122 | 2.49e-09 | |||||
divergent subfamily of APPLE domains; Apple-like domains present in Plasminogen, C. elegans hypothetical ORFs and the extracellular portion of plant receptor-like protein kinases. Predicted to possess protein- and/or carbohydrate-binding functions. Pssm-ID: 214680 Cd Length: 78 Bit Score: 54.51 E-value: 2.49e-09
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PAN_1 | pfam00024 | PAN domain; The PAN domain contains a conserved core of three disulphide bridges. In some ... |
41-121 | 7.69e-09 | |||||
PAN domain; The PAN domain contains a conserved core of three disulphide bridges. In some members of the family there is an additional fourth disulphide bridge the links the N and C termini of the domain. The domain is found in diverse proteins, in some they mediate protein-protein interactions, in others they mediate protein-carbohydrate interactions. Pssm-ID: 459635 Cd Length: 76 Bit Score: 52.94 E-value: 7.69e-09
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Name | Accession | Description | Interval | E-value | |||||
Tryp_SPc | smart00020 | Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens ... |
494-716 | 5.85e-67 | |||||
Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues. Pssm-ID: 214473 Cd Length: 229 Bit Score: 220.24 E-value: 5.85e-67
|
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Tryp_SPc | cd00190 | Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens ... |
495-719 | 4.55e-66 | |||||
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues. Pssm-ID: 238113 [Multi-domain] Cd Length: 232 Bit Score: 218.30 E-value: 4.55e-66
|
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Trypsin | pfam00089 | Trypsin; |
495-716 | 9.22e-56 | |||||
Trypsin; Pssm-ID: 459667 [Multi-domain] Cd Length: 219 Bit Score: 189.96 E-value: 9.22e-56
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
210-290 | 6.00e-41 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 144.07 E-value: 6.00e-41
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
211-288 | 5.00e-39 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 138.59 E-value: 5.00e-39
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
126-208 | 1.45e-38 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 137.52 E-value: 1.45e-38
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
208-289 | 5.18e-38 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 135.97 E-value: 5.18e-38
|
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COG5640 | COG5640 | Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, ... |
488-720 | 5.69e-38 | |||||
Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 444365 [Multi-domain] Cd Length: 262 Bit Score: 142.10 E-value: 5.69e-38
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
126-207 | 7.03e-38 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 135.58 E-value: 7.03e-38
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
304-384 | 1.61e-37 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 134.44 E-value: 1.61e-37
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
305-383 | 3.40e-37 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 133.59 E-value: 3.40e-37
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
302-384 | 7.91e-37 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 132.50 E-value: 7.91e-37
|
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KR | cd00108 | Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
388-470 | 4.25e-34 | |||||
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides. Pssm-ID: 238056 Cd Length: 83 Bit Score: 124.80 E-value: 4.25e-34
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
128-206 | 1.07e-33 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 123.57 E-value: 1.07e-33
|
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KR | smart00130 | Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
389-471 | 1.39e-33 | |||||
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides. Pssm-ID: 214527 Cd Length: 83 Bit Score: 123.27 E-value: 1.39e-33
|
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Kringle | pfam00051 | Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
391-469 | 1.19e-31 | |||||
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta. Pssm-ID: 395005 Cd Length: 79 Bit Score: 117.79 E-value: 1.19e-31
|
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PAN_APPLE | cd00129 | PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth ... |
39-122 | 1.30e-27 | |||||
PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech anti-platelet proteins. Common structural features include two disulfide bonds that link the alpha-helix to the central region of the protein. PAN domains have significant functional versatility, fulfilling diverse biological functions by mediating protein-protein or protein-carbohydrate interactions. Pssm-ID: 238074 Cd Length: 80 Bit Score: 106.24 E-value: 1.30e-27
|
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PAN_AP_HGF | cd01099 | Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen ... |
40-122 | 1.82e-14 | |||||
Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions by mediating protein-protein or protein-carbohydrate interactions. Pssm-ID: 238532 Cd Length: 80 Bit Score: 69.04 E-value: 1.82e-14
|
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PAN_AP | smart00473 | divergent subfamily of APPLE domains; Apple-like domains present in Plasminogen, C. elegans ... |
37-122 | 2.49e-09 | |||||
divergent subfamily of APPLE domains; Apple-like domains present in Plasminogen, C. elegans hypothetical ORFs and the extracellular portion of plant receptor-like protein kinases. Predicted to possess protein- and/or carbohydrate-binding functions. Pssm-ID: 214680 Cd Length: 78 Bit Score: 54.51 E-value: 2.49e-09
|
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PAN_1 | pfam00024 | PAN domain; The PAN domain contains a conserved core of three disulphide bridges. In some ... |
41-121 | 7.69e-09 | |||||
PAN domain; The PAN domain contains a conserved core of three disulphide bridges. In some members of the family there is an additional fourth disulphide bridge the links the N and C termini of the domain. The domain is found in diverse proteins, in some they mediate protein-protein interactions, in others they mediate protein-carbohydrate interactions. Pssm-ID: 459635 Cd Length: 76 Bit Score: 52.94 E-value: 7.69e-09
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APPLE_Factor_XI_like | cd01100 | Subfamily of PAN/APPLE-like domains; present in plasma prekallikrein/coagulation factor XI, ... |
59-97 | 4.10e-03 | |||||
Subfamily of PAN/APPLE-like domains; present in plasma prekallikrein/coagulation factor XI, microneme antigen proteins, and a few prokaryotic proteins. PAN/APPLE domains fulfill diverse biological functions by mediating protein-protein or protein-carbohydrate interactions. Pssm-ID: 238533 Cd Length: 73 Bit Score: 36.64 E-value: 4.10e-03
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Blast search parameters | ||||
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