|
Name |
Accession |
Description |
Interval |
E-value |
| APC_basic |
pfam05956 |
APC basic domain; This region of the APC family of proteins is known as the basic domain. It ... |
1785-2112 |
5.39e-94 |
|
APC basic domain; This region of the APC family of proteins is known as the basic domain. It contains a high proportion of positively charged amino acids and interacts with microtubules.
:
Pssm-ID: 428690 [Multi-domain] Cd Length: 336 Bit Score: 308.34 E-value: 5.39e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1785 AVLRGRTVIYVPSpAPRAQPKGTPGPRATPRKVAppclaqpaAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPP 1864
Cdd:pfam05956 1 VVFRGRTVIYMPG-VKESQPSTSPPPKKTPPKTD--------APAKNPNLGQQRSRSLHRLGKPSELADLSPPKRSATPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1865 ARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGAS------PVPKTPARTLLAKQ--HKTQRSPVRIPFMQRPA 1936
Cdd:pfam05956 72 ARISKAPSSGSSRDSTPSRPPQKKLTSPSQSPGRLPGSGGRnklsplPKTKSPARASTKKSgsHKTQKSPVRIPFMQTPT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1937 R-----RGPPPLARAVPEPgpRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRsGFRRQLTFIKESPG-LRRRRSEL 2010
Cdd:pfam05956 152 KqtglpRNPSPLVTNQPEP--RSESASKGLRSLPGKRLDLVRMSSARSSGSESDRS-GFLRQLTFIKESPSlLLRRRLEL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2011 SSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAA 2090
Cdd:pfam05956 229 SASESLSPSSQPASPRRSRPGLPAVFLCSSRCQELKGWRKQPPNPNSRAEPSDRPLTRRRPPRRTSSESPSRLPVRNGTW 308
|
330 340
....*....|....*....|..
gi 1189438290 2091 RPETVKRYASLPHISVARRPDG 2112
Cdd:pfam05956 309 KRETFKRYSSLPHINVWRRTGS 330
|
|
| APC_rep |
pfam18797 |
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo ... |
356-430 |
2.75e-33 |
|
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo repeat and uses its highly conserved surface groove to recognize the APC-binding region (ABR) of Asef. This entry represents a single repeat unit of the Armadillo region.
:
Pssm-ID: 465870 Cd Length: 74 Bit Score: 123.81 E-value: 2.75e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1189438290 356 SQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPEGGGAGSaPIPIEPQICQATCAVMKLSFDEEYRRAM 430
Cdd:pfam18797 1 SQPDDKRGRREMRVLHLLEQIRAYCETCWDWQESHSRGPEGDSNPM-PSPIEHQICPAICALMKLSFDEEHRHAM 74
|
|
| APC_N_CC |
pfam16689 |
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil ... |
6-57 |
8.01e-26 |
|
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil dimerization domain of the adenomatosis polyposis coli (APC) tumour-repressor proteins. It plays a key role in the regulation of cellular levels of the oncogene product beta-catenin. Coiled-coil regions are binding repeats that in this case bind to the armadillo repeat region of beta-catenin.
:
Pssm-ID: 435517 Cd Length: 52 Bit Score: 101.99 E-value: 8.01e-26
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1189438290 6 APYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKL 57
Cdd:pfam16689 1 ASYDQLLRQVEALKLENTTLRQELRDNSSHLSKLETEASNMKEVLKHLQGSI 52
|
|
| Arm_APC_u3 super family |
cl25003 |
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately ... |
696-943 |
2.01e-20 |
|
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately downstream of the armadillo fold before the beta-catenin binding motifs, APC_crr, pfam05923, on APC or adenomatous polyposis coli proteins in higher eukaryotes. The function is not known.
The actual alignment was detected with superfamily member pfam16629:
Pssm-ID: 435476 Cd Length: 293 Bit Score: 94.27 E-value: 2.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 696 HRPAKHQAAaTAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKQGPPAAEaaTKKPlpplRHLDGLAQDYASDSG 775
Cdd:pfam16629 1 NRPAKYKDA-NIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASH--RNKQ----RHKQNVYSEYVLDSG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 776 CFDDDDAPSSlaaaaaTGEPASPAALSLFLGSPFLQGQAlARTPPTRRGGKEAEKDTSGEAAVAAKAKA----------- 844
Cdd:pfam16629 74 RHDDSVCRSD------NFNTGNVTVLSPYLNTTVLPSSS-SRDSRGNAESSRSEKDRSLDRERGAGLSNfhpatensgns 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 845 ------KLALAVARIDQLVEDISALHTSSDDSFSLSSGDP---GQEAPREGRAQSCSPCRGPEG-GRREAGSRAHPLLRL 914
Cdd:pfam16629 147 skrigmQISTTAAQIAKVMEEVSSMHISQEDRSSGSTSDMhcmQDDRNSIRRSSTAHPHSNVYSfNKSESSNRPCPMPYM 226
|
250 260
....*....|....*....|....*....
gi 1189438290 915 KAAHASLSNDSLNSGSASDGYCPREHMLP 943
Cdd:pfam16629 227 KMEYKRASNDSLNSVSSSDGYGKRGQMKP 255
|
|
| Suppressor_APC |
pfam11414 |
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ... |
124-204 |
1.47e-18 |
|
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.
:
Pssm-ID: 463275 Cd Length: 82 Bit Score: 81.92 E-value: 1.47e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 124 SRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVET-FSMQMDLIRQQLEFEAQHIRSLMEERFG 202
Cdd:pfam11414 1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTyFDYGSDAQQERLEFLLARIQEVNRCLGG 80
|
..
gi 1189438290 203 TS 204
Cdd:pfam11414 81 LI 82
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
1314-1910 |
6.28e-08 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.41 E-value: 6.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1314 FAGHRRREEGP--APTGSRPRG-AADQELELLRECLGAavPARLRKVASALVPGRRALPVPV---YMLVPAPAPAQEDDS 1387
Cdd:PHA03247 2425 FVGSEEIEELPfvSPGGDVLAGlAADGDPFFARTILGA--PFSLSLLLGELFPGAPVYRRPAearFPFAAGAAPDPGGGG 2502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1388 CTDSAEGTPVNFSSAASLSDETLQGP--PR-------------DQPGGPAGRQRPTGRPTSARQAMGHRHKAGGAGRSAE 1452
Cdd:PHA03247 2503 PPDPDAPPAPSRLAPAILPDEPVGEPvhPRmltwirgleelasDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAV 2582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1453 QSRGAgknraglelplgRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVY-------CFYGNDSDEEPPAAAPTPT 1525
Cdd:PHA03247 2583 TSRAR------------RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPdppppspSPAANEPDPHPPPTVPPPE 2650
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1526 HRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSL-----IADETPPCYSLSSSASSLSEPEPSEPPAVHPRG 1600
Cdd:PHA03247 2651 RPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVgsltsLADPPPPPPTPEPAPHALVSATPLPPGPAAARQ 2730
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1601 REPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATrldeRPAEGSRERGEEAAGSDRasdl 1680
Cdd:PHA03247 2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSESRESLPSPW---- 2802
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1681 DSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGlsvgsTLQPPKHRKGRQAEGEmGSARRPEKRGAASVkt 1760
Cdd:PHA03247 2803 DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----PPPPSLPLGGSVAPGG-DVRRRPPSRSPAAK-- 2874
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1761 sgsprsPAGPEKPRGTQKTTPGVPavlrgrtviyvPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPG-QQRS 1839
Cdd:PHA03247 2875 ------PAAPARPPVRRLARPAVS-----------RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPpPPPP 2937
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1189438290 1840 RSLHRPAKTSELATLSQPPRSATPPARLAktpsssssqTSPASQPLPRKRPPvtQAAGALPGPGASPVPKT 1910
Cdd:PHA03247 2938 RPQPPLAPTTDPAGAGEPSGAVPQPWLGA---------LVPGRVAVPRFRVP--QPAPSREAPASSTPPLT 2997
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
614-653 |
1.17e-06 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
:
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 47.06 E-value: 1.17e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1189438290 614 EDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 653
Cdd:pfam00514 2 PENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
2001-2226 |
4.84e-05 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 4.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2001 PGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSP----GERPARRTT 2076
Cdd:PHA03247 258 PPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPPPAPAGDAeeedDEDGAMEVV 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2077 SESP---SRLPVRAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAAR-------RSSDGEPRPLPRVAAPGTTwr 2146
Cdd:PHA03247 338 SPLPrprQHYPLGFPKRRRPTWTPPSSLEDLSAGRHHPKRASLPTRKRRSARhaatpfaRGPGGDDQTRPAAPVPASV-- 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2147 riRDEDVPHILRSTLPATALPLRGSTPeDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLET---REPPGAPAGGQLS 2223
Cdd:PHA03247 416 --PTPAPTPVPASAPPPPATPLPSAEP-GSDDGPAPPPERQPPAPATEPAPDDPDDATRKALDAlreRRPPEPPGADLAE 492
|
...
gi 1189438290 2224 LLG 2226
Cdd:PHA03247 493 LLG 495
|
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1259-1280 |
2.38e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
:
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.38e-03
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
524-561 |
9.38e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
:
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.38e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1189438290 524 KKVLREAGSVTALVQCvLRATKESTLKSVLSALWNLSA 561
Cdd:pfam00514 5 KQAVIEAGAVPPLVRL-LSSPDEEVQEEAAWALSNLAA 41
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
660-695 |
9.76e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
:
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.76e-03
10 20 30
....*....|....*....|....*....|....*.
gi 1189438290 660 ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA 695
Cdd:pfam00514 6 QAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APC_basic |
pfam05956 |
APC basic domain; This region of the APC family of proteins is known as the basic domain. It ... |
1785-2112 |
5.39e-94 |
|
APC basic domain; This region of the APC family of proteins is known as the basic domain. It contains a high proportion of positively charged amino acids and interacts with microtubules.
Pssm-ID: 428690 [Multi-domain] Cd Length: 336 Bit Score: 308.34 E-value: 5.39e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1785 AVLRGRTVIYVPSpAPRAQPKGTPGPRATPRKVAppclaqpaAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPP 1864
Cdd:pfam05956 1 VVFRGRTVIYMPG-VKESQPSTSPPPKKTPPKTD--------APAKNPNLGQQRSRSLHRLGKPSELADLSPPKRSATPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1865 ARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGAS------PVPKTPARTLLAKQ--HKTQRSPVRIPFMQRPA 1936
Cdd:pfam05956 72 ARISKAPSSGSSRDSTPSRPPQKKLTSPSQSPGRLPGSGGRnklsplPKTKSPARASTKKSgsHKTQKSPVRIPFMQTPT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1937 R-----RGPPPLARAVPEPgpRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRsGFRRQLTFIKESPG-LRRRRSEL 2010
Cdd:pfam05956 152 KqtglpRNPSPLVTNQPEP--RSESASKGLRSLPGKRLDLVRMSSARSSGSESDRS-GFLRQLTFIKESPSlLLRRRLEL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2011 SSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAA 2090
Cdd:pfam05956 229 SASESLSPSSQPASPRRSRPGLPAVFLCSSRCQELKGWRKQPPNPNSRAEPSDRPLTRRRPPRRTSSESPSRLPVRNGTW 308
|
330 340
....*....|....*....|..
gi 1189438290 2091 RPETVKRYASLPHISVARRPDG 2112
Cdd:pfam05956 309 KRETFKRYSSLPHINVWRRTGS 330
|
|
| APC_rep |
pfam18797 |
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo ... |
356-430 |
2.75e-33 |
|
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo repeat and uses its highly conserved surface groove to recognize the APC-binding region (ABR) of Asef. This entry represents a single repeat unit of the Armadillo region.
Pssm-ID: 465870 Cd Length: 74 Bit Score: 123.81 E-value: 2.75e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1189438290 356 SQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPEGGGAGSaPIPIEPQICQATCAVMKLSFDEEYRRAM 430
Cdd:pfam18797 1 SQPDDKRGRREMRVLHLLEQIRAYCETCWDWQESHSRGPEGDSNPM-PSPIEHQICPAICALMKLSFDEEHRHAM 74
|
|
| APC_N_CC |
pfam16689 |
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil ... |
6-57 |
8.01e-26 |
|
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil dimerization domain of the adenomatosis polyposis coli (APC) tumour-repressor proteins. It plays a key role in the regulation of cellular levels of the oncogene product beta-catenin. Coiled-coil regions are binding repeats that in this case bind to the armadillo repeat region of beta-catenin.
Pssm-ID: 435517 Cd Length: 52 Bit Score: 101.99 E-value: 8.01e-26
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1189438290 6 APYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKL 57
Cdd:pfam16689 1 ASYDQLLRQVEALKLENTTLRQELRDNSSHLSKLETEASNMKEVLKHLQGSI 52
|
|
| Arm_APC_u3 |
pfam16629 |
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately ... |
696-943 |
2.01e-20 |
|
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately downstream of the armadillo fold before the beta-catenin binding motifs, APC_crr, pfam05923, on APC or adenomatous polyposis coli proteins in higher eukaryotes. The function is not known.
Pssm-ID: 435476 Cd Length: 293 Bit Score: 94.27 E-value: 2.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 696 HRPAKHQAAaTAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKQGPPAAEaaTKKPlpplRHLDGLAQDYASDSG 775
Cdd:pfam16629 1 NRPAKYKDA-NIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASH--RNKQ----RHKQNVYSEYVLDSG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 776 CFDDDDAPSSlaaaaaTGEPASPAALSLFLGSPFLQGQAlARTPPTRRGGKEAEKDTSGEAAVAAKAKA----------- 844
Cdd:pfam16629 74 RHDDSVCRSD------NFNTGNVTVLSPYLNTTVLPSSS-SRDSRGNAESSRSEKDRSLDRERGAGLSNfhpatensgns 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 845 ------KLALAVARIDQLVEDISALHTSSDDSFSLSSGDP---GQEAPREGRAQSCSPCRGPEG-GRREAGSRAHPLLRL 914
Cdd:pfam16629 147 skrigmQISTTAAQIAKVMEEVSSMHISQEDRSSGSTSDMhcmQDDRNSIRRSSTAHPHSNVYSfNKSESSNRPCPMPYM 226
|
250 260
....*....|....*....|....*....
gi 1189438290 915 KAAHASLSNDSLNSGSASDGYCPREHMLP 943
Cdd:pfam16629 227 KMEYKRASNDSLNSVSSSDGYGKRGQMKP 255
|
|
| Suppressor_APC |
pfam11414 |
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ... |
124-204 |
1.47e-18 |
|
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.
Pssm-ID: 463275 Cd Length: 82 Bit Score: 81.92 E-value: 1.47e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 124 SRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVET-FSMQMDLIRQQLEFEAQHIRSLMEERFG 202
Cdd:pfam11414 1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTyFDYGSDAQQERLEFLLARIQEVNRCLGG 80
|
..
gi 1189438290 203 TS 204
Cdd:pfam11414 81 LI 82
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1565-2097 |
2.47e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 76.52 E-value: 2.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1565 PSLIADETPPCYSLSSSASSLSEPEPSEPpAVHPRGREPAVTKDPG----PGGGRDSSPSPRAAEELlqrciSSALPRRR 1640
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEP-AVTSRARRPDAPPQSArpraPVDDRGDPRGPAPPSPL-----PPDTHAPD 2625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1641 PPVSGlRRRKPRATRLDERPAEGSRERGEEAAGSDRASdldsvewraiqegansivtwLHQAAAATREASSESdsilsfv 1720
Cdd:PHA03247 2626 PPPPS-PSPAANEPDPHPPPTVPPPERPRDDPAPGRVS--------------------RPRRARRLGRAAQAS------- 2677
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1721 sglsvgSTLQPPKHRKGRQAEGEMGSARRPEKrgaasvktsgSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAP 1800
Cdd:PHA03247 2678 ------SPPQRPRRRAARPTVGSLTSLADPPP----------PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAP 2741
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1801 RAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPrSATPPARLAKTPSSSSSQTSP 1880
Cdd:PHA03247 2742 PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP-SPWDPADPPAAVLAPAAALPP 2820
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1881 ASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPlARAVPEPGPRGRAGTEA 1960
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPP-VRRLARPAVSRSTESFA 2899
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1961 GPGARGGRLGLVRVASALSSGSESSDRSGFRRQLtfikESPGLRRRRSELSSAESAASAPQGASPrrgRPALPAVFLCSS 2040
Cdd:PHA03247 2900 LPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP----PPPPRPQPPLAPTTDPAGAGEPSGAVP---QPWLGALVPGRV 2972
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1189438290 2041 RCEELRAAPrqgPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKR 2097
Cdd:PHA03247 2973 AVPRFRVPQ---PAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKQ 3026
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1314-1910 |
6.28e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.41 E-value: 6.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1314 FAGHRRREEGP--APTGSRPRG-AADQELELLRECLGAavPARLRKVASALVPGRRALPVPV---YMLVPAPAPAQEDDS 1387
Cdd:PHA03247 2425 FVGSEEIEELPfvSPGGDVLAGlAADGDPFFARTILGA--PFSLSLLLGELFPGAPVYRRPAearFPFAAGAAPDPGGGG 2502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1388 CTDSAEGTPVNFSSAASLSDETLQGP--PR-------------DQPGGPAGRQRPTGRPTSARQAMGHRHKAGGAGRSAE 1452
Cdd:PHA03247 2503 PPDPDAPPAPSRLAPAILPDEPVGEPvhPRmltwirgleelasDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAV 2582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1453 QSRGAgknraglelplgRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVY-------CFYGNDSDEEPPAAAPTPT 1525
Cdd:PHA03247 2583 TSRAR------------RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPdppppspSPAANEPDPHPPPTVPPPE 2650
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1526 HRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSL-----IADETPPCYSLSSSASSLSEPEPSEPPAVHPRG 1600
Cdd:PHA03247 2651 RPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVgsltsLADPPPPPPTPEPAPHALVSATPLPPGPAAARQ 2730
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1601 REPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATrldeRPAEGSRERGEEAAGSDRasdl 1680
Cdd:PHA03247 2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSESRESLPSPW---- 2802
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1681 DSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGlsvgsTLQPPKHRKGRQAEGEmGSARRPEKRGAASVkt 1760
Cdd:PHA03247 2803 DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----PPPPSLPLGGSVAPGG-DVRRRPPSRSPAAK-- 2874
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1761 sgsprsPAGPEKPRGTQKTTPGVPavlrgrtviyvPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPG-QQRS 1839
Cdd:PHA03247 2875 ------PAAPARPPVRRLARPAVS-----------RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPpPPPP 2937
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1189438290 1840 RSLHRPAKTSELATLSQPPRSATPPARLAktpsssssqTSPASQPLPRKRPPvtQAAGALPGPGASPVPKT 1910
Cdd:PHA03247 2938 RPQPPLAPTTDPAGAGEPSGAVPQPWLGA---------LVPGRVAVPRFRVP--QPAPSREAPASSTPPLT 2997
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
614-653 |
1.17e-06 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 47.06 E-value: 1.17e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1189438290 614 EDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 653
Cdd:pfam00514 2 PENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| ARM |
smart00185 |
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ... |
613-653 |
1.76e-06 |
|
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.
Pssm-ID: 214547 [Multi-domain] Cd Length: 41 Bit Score: 46.27 E-value: 1.76e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1189438290 613 REDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 653
Cdd:smart00185 1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2001-2226 |
4.84e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 4.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2001 PGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSP----GERPARRTT 2076
Cdd:PHA03247 258 PPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPPPAPAGDAeeedDEDGAMEVV 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2077 SESP---SRLPVRAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAAR-------RSSDGEPRPLPRVAAPGTTwr 2146
Cdd:PHA03247 338 SPLPrprQHYPLGFPKRRRPTWTPPSSLEDLSAGRHHPKRASLPTRKRRSARhaatpfaRGPGGDDQTRPAAPVPASV-- 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2147 riRDEDVPHILRSTLPATALPLRGSTPeDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLET---REPPGAPAGGQLS 2223
Cdd:PHA03247 416 --PTPAPTPVPASAPPPPATPLPSAEP-GSDDGPAPPPERQPPAPATEPAPDDPDDATRKALDAlreRRPPEPPGADLAE 492
|
...
gi 1189438290 2224 LLG 2226
Cdd:PHA03247 493 LLG 495
|
|
| SAMP |
pfam05924 |
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1620-1641 |
1.77e-03 |
|
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). This motif binds axin.
Pssm-ID: 461782 Cd Length: 22 Bit Score: 37.57 E-value: 1.77e-03
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1259-1280 |
2.38e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.38e-03
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
524-561 |
9.38e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.38e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1189438290 524 KKVLREAGSVTALVQCvLRATKESTLKSVLSALWNLSA 561
Cdd:pfam00514 5 KQAVIEAGAVPPLVRL-LSSPDEEVQEEAAWALSNLAA 41
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
660-695 |
9.76e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.76e-03
10 20 30
....*....|....*....|....*....|....*.
gi 1189438290 660 ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA 695
Cdd:pfam00514 6 QAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APC_basic |
pfam05956 |
APC basic domain; This region of the APC family of proteins is known as the basic domain. It ... |
1785-2112 |
5.39e-94 |
|
APC basic domain; This region of the APC family of proteins is known as the basic domain. It contains a high proportion of positively charged amino acids and interacts with microtubules.
Pssm-ID: 428690 [Multi-domain] Cd Length: 336 Bit Score: 308.34 E-value: 5.39e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1785 AVLRGRTVIYVPSpAPRAQPKGTPGPRATPRKVAppclaqpaAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPP 1864
Cdd:pfam05956 1 VVFRGRTVIYMPG-VKESQPSTSPPPKKTPPKTD--------APAKNPNLGQQRSRSLHRLGKPSELADLSPPKRSATPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1865 ARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGAS------PVPKTPARTLLAKQ--HKTQRSPVRIPFMQRPA 1936
Cdd:pfam05956 72 ARISKAPSSGSSRDSTPSRPPQKKLTSPSQSPGRLPGSGGRnklsplPKTKSPARASTKKSgsHKTQKSPVRIPFMQTPT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1937 R-----RGPPPLARAVPEPgpRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRsGFRRQLTFIKESPG-LRRRRSEL 2010
Cdd:pfam05956 152 KqtglpRNPSPLVTNQPEP--RSESASKGLRSLPGKRLDLVRMSSARSSGSESDRS-GFLRQLTFIKESPSlLLRRRLEL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2011 SSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAA 2090
Cdd:pfam05956 229 SASESLSPSSQPASPRRSRPGLPAVFLCSSRCQELKGWRKQPPNPNSRAEPSDRPLTRRRPPRRTSSESPSRLPVRNGTW 308
|
330 340
....*....|....*....|..
gi 1189438290 2091 RPETVKRYASLPHISVARRPDG 2112
Cdd:pfam05956 309 KRETFKRYSSLPHINVWRRTGS 330
|
|
| APC_rep |
pfam18797 |
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo ... |
356-430 |
2.75e-33 |
|
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo repeat and uses its highly conserved surface groove to recognize the APC-binding region (ABR) of Asef. This entry represents a single repeat unit of the Armadillo region.
Pssm-ID: 465870 Cd Length: 74 Bit Score: 123.81 E-value: 2.75e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1189438290 356 SQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPEGGGAGSaPIPIEPQICQATCAVMKLSFDEEYRRAM 430
Cdd:pfam18797 1 SQPDDKRGRREMRVLHLLEQIRAYCETCWDWQESHSRGPEGDSNPM-PSPIEHQICPAICALMKLSFDEEHRHAM 74
|
|
| APC_N_CC |
pfam16689 |
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil ... |
6-57 |
8.01e-26 |
|
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil dimerization domain of the adenomatosis polyposis coli (APC) tumour-repressor proteins. It plays a key role in the regulation of cellular levels of the oncogene product beta-catenin. Coiled-coil regions are binding repeats that in this case bind to the armadillo repeat region of beta-catenin.
Pssm-ID: 435517 Cd Length: 52 Bit Score: 101.99 E-value: 8.01e-26
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1189438290 6 APYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKL 57
Cdd:pfam16689 1 ASYDQLLRQVEALKLENTTLRQELRDNSSHLSKLETEASNMKEVLKHLQGSI 52
|
|
| Arm_APC_u3 |
pfam16629 |
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately ... |
696-943 |
2.01e-20 |
|
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately downstream of the armadillo fold before the beta-catenin binding motifs, APC_crr, pfam05923, on APC or adenomatous polyposis coli proteins in higher eukaryotes. The function is not known.
Pssm-ID: 435476 Cd Length: 293 Bit Score: 94.27 E-value: 2.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 696 HRPAKHQAAaTAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKQGPPAAEaaTKKPlpplRHLDGLAQDYASDSG 775
Cdd:pfam16629 1 NRPAKYKDA-NIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASH--RNKQ----RHKQNVYSEYVLDSG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 776 CFDDDDAPSSlaaaaaTGEPASPAALSLFLGSPFLQGQAlARTPPTRRGGKEAEKDTSGEAAVAAKAKA----------- 844
Cdd:pfam16629 74 RHDDSVCRSD------NFNTGNVTVLSPYLNTTVLPSSS-SRDSRGNAESSRSEKDRSLDRERGAGLSNfhpatensgns 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 845 ------KLALAVARIDQLVEDISALHTSSDDSFSLSSGDP---GQEAPREGRAQSCSPCRGPEG-GRREAGSRAHPLLRL 914
Cdd:pfam16629 147 skrigmQISTTAAQIAKVMEEVSSMHISQEDRSSGSTSDMhcmQDDRNSIRRSSTAHPHSNVYSfNKSESSNRPCPMPYM 226
|
250 260
....*....|....*....|....*....
gi 1189438290 915 KAAHASLSNDSLNSGSASDGYCPREHMLP 943
Cdd:pfam16629 227 KMEYKRASNDSLNSVSSSDGYGKRGQMKP 255
|
|
| Suppressor_APC |
pfam11414 |
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ... |
124-204 |
1.47e-18 |
|
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.
Pssm-ID: 463275 Cd Length: 82 Bit Score: 81.92 E-value: 1.47e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 124 SRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVET-FSMQMDLIRQQLEFEAQHIRSLMEERFG 202
Cdd:pfam11414 1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTyFDYGSDAQQERLEFLLARIQEVNRCLGG 80
|
..
gi 1189438290 203 TS 204
Cdd:pfam11414 81 LI 82
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1565-2097 |
2.47e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 76.52 E-value: 2.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1565 PSLIADETPPCYSLSSSASSLSEPEPSEPpAVHPRGREPAVTKDPG----PGGGRDSSPSPRAAEELlqrciSSALPRRR 1640
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEP-AVTSRARRPDAPPQSArpraPVDDRGDPRGPAPPSPL-----PPDTHAPD 2625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1641 PPVSGlRRRKPRATRLDERPAEGSRERGEEAAGSDRASdldsvewraiqegansivtwLHQAAAATREASSESdsilsfv 1720
Cdd:PHA03247 2626 PPPPS-PSPAANEPDPHPPPTVPPPERPRDDPAPGRVS--------------------RPRRARRLGRAAQAS------- 2677
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1721 sglsvgSTLQPPKHRKGRQAEGEMGSARRPEKrgaasvktsgSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAP 1800
Cdd:PHA03247 2678 ------SPPQRPRRRAARPTVGSLTSLADPPP----------PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAP 2741
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1801 RAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPrSATPPARLAKTPSSSSSQTSP 1880
Cdd:PHA03247 2742 PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP-SPWDPADPPAAVLAPAAALPP 2820
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1881 ASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPlARAVPEPGPRGRAGTEA 1960
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPP-VRRLARPAVSRSTESFA 2899
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1961 GPGARGGRLGLVRVASALSSGSESSDRSGFRRQLtfikESPGLRRRRSELSSAESAASAPQGASPrrgRPALPAVFLCSS 2040
Cdd:PHA03247 2900 LPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP----PPPPRPQPPLAPTTDPAGAGEPSGAVP---QPWLGALVPGRV 2972
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1189438290 2041 RCEELRAAPrqgPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKR 2097
Cdd:PHA03247 2973 AVPRFRVPQ---PAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKQ 3026
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1731-2244 |
1.12e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.20 E-value: 1.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1731 PPKHRKGRQAEGEMGSARRPEKRGAASVKTSgSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGT--- 1807
Cdd:PHA03247 2592 PPQSARPRAPVDDRGDPRGPAPPSPLPPDTH-APDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRArrl 2670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1808 ---PGPRATPRKVAPPCLAQPAAP----AKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSP 1880
Cdd:PHA03247 2671 graAQASSPPQRPRRRAARPTVGSltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1881 ASQPLPRKRPPVTQAAGAlPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEA 1960
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPA-PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1961 GPGArggrlglvrvASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASPRRGRPALPavflcss 2040
Cdd:PHA03247 2830 PPTS----------AQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVS------- 2892
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2041 RCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPA-ARPETVKRYASLPHISVARRPDGAVPAAPA 2119
Cdd:PHA03247 2893 RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPpLAPTTDPAGAGEPSGAVPQPWLGALVPGRV 2972
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2120 SADAARRSSDGEPRPLPrvAAPGTTWRRIRDEDVP--------HILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQ 2191
Cdd:PHA03247 2973 AVPRFRVPQPAPSREAP--ASSTPPLTGHSLSRVSswasslalHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERS 3050
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 1189438290 2192 TEEVAAPKTNSSTSPSleTREP-PGAPAGGQLSLLGSDVDGPSL-AKAPISAPFV 2244
Cdd:PHA03247 3051 DLEALDPLPPEPHDPF--AHEPdPATPEAGARESPSSQFGPPPLsANAALSRRYV 3103
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1314-1910 |
6.28e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.41 E-value: 6.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1314 FAGHRRREEGP--APTGSRPRG-AADQELELLRECLGAavPARLRKVASALVPGRRALPVPV---YMLVPAPAPAQEDDS 1387
Cdd:PHA03247 2425 FVGSEEIEELPfvSPGGDVLAGlAADGDPFFARTILGA--PFSLSLLLGELFPGAPVYRRPAearFPFAAGAAPDPGGGG 2502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1388 CTDSAEGTPVNFSSAASLSDETLQGP--PR-------------DQPGGPAGRQRPTGRPTSARQAMGHRHKAGGAGRSAE 1452
Cdd:PHA03247 2503 PPDPDAPPAPSRLAPAILPDEPVGEPvhPRmltwirgleelasDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAV 2582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1453 QSRGAgknraglelplgRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVY-------CFYGNDSDEEPPAAAPTPT 1525
Cdd:PHA03247 2583 TSRAR------------RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPdppppspSPAANEPDPHPPPTVPPPE 2650
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1526 HRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSL-----IADETPPCYSLSSSASSLSEPEPSEPPAVHPRG 1600
Cdd:PHA03247 2651 RPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVgsltsLADPPPPPPTPEPAPHALVSATPLPPGPAAARQ 2730
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1601 REPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATrldeRPAEGSRERGEEAAGSDRasdl 1680
Cdd:PHA03247 2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT----RPAVASLSESRESLPSPW---- 2802
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1681 DSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGlsvgsTLQPPKHRKGRQAEGEmGSARRPEKRGAASVkt 1760
Cdd:PHA03247 2803 DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----PPPPSLPLGGSVAPGG-DVRRRPPSRSPAAK-- 2874
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1761 sgsprsPAGPEKPRGTQKTTPGVPavlrgrtviyvPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPG-QQRS 1839
Cdd:PHA03247 2875 ------PAAPARPPVRRLARPAVS-----------RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPpPPPP 2937
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1189438290 1840 RSLHRPAKTSELATLSQPPRSATPPARLAktpsssssqTSPASQPLPRKRPPvtQAAGALPGPGASPVPKT 1910
Cdd:PHA03247 2938 RPQPPLAPTTDPAGAGEPSGAVPQPWLGA---------LVPGRVAVPRFRVP--QPAPSREAPASSTPPLT 2997
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1790-2278 |
9.61e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.56 E-value: 9.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1790 RTVIYVPSPAPRAQPKGTPGPRATPRkvaPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATL---SQPPRSATPPAR 1866
Cdd:PHA03247 2457 RTILGAPFSLSLLLGELFPGAPVYRR---PAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpDEPVGEPVHPRM 2533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1867 LAKTPSSSSSQTSPASQPLPRKRPPVTQAAG--ALPGPGASPVPKTPARTLLAK------QHKTQRSPV--RIPFMQRPA 1936
Cdd:PHA03247 2534 LTWIRGLEELASDDAGDPPPPLPPAAPPAAPdrSVPPPRPAPRPSEPAVTSRARrpdappQSARPRAPVddRGDPRGPAP 2613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1937 RRGPPPLARAVPEPGPRGR-AGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAES 2015
Cdd:PHA03247 2614 PSPLPPDTHAPDPPPPSPSpAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVG 2693
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2016 AASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSP---------GERPARRTTSESPSRLPVR 2086
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPagpatpggpARPARPPTTAGPPAPAPPA 2773
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2087 APAA-------RPETVKRYASLPHISVARRP-DGAVPAAPASADAARRSSDGEPRPLPRVAAPgttwrrirdedVPHILR 2158
Cdd:PHA03247 2774 APAAgpprrltRPAVASLSESRESLPSPWDPaDPPAAVLAPAAALPPAASPAGPLPPPTSAQP-----------TAPPPP 2842
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2159 STLPATALPLRGS-----------------TPEDAPAGPPPRKTSDAVV--QTEEVAAPKTNSSTSPSLETREPPGAPAG 2219
Cdd:PHA03247 2843 PGPPPPSLPLGGSvapggdvrrrppsrspaAKPAAPARPPVRRLARPAVsrSTESFALPPDQPERPPQPQAPPPPQPQPQ 2922
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2220 GQLSLLGSDV-DGPSLAKAPISAPFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSP 2278
Cdd:PHA03247 2923 PPPPPQPQPPpPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQP 2982
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
614-653 |
1.17e-06 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 47.06 E-value: 1.17e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1189438290 614 EDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 653
Cdd:pfam00514 2 PENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| ARM |
smart00185 |
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ... |
613-653 |
1.76e-06 |
|
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.
Pssm-ID: 214547 [Multi-domain] Cd Length: 41 Bit Score: 46.27 E-value: 1.76e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1189438290 613 REDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 653
Cdd:smart00185 1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1587-1961 |
6.03e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 51.71 E-value: 6.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1587 EPEPSEPPAVHPRGREPA-VTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPvsgLRRRKPRATRLDERPAEGSR 1665
Cdd:PHA03307 81 ANESRSTPTWSLSTLAPAsPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEM---LRPVGSPGPPPAASPPAAGA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1666 ERGEEAAGSDRASDLDSvewraiqegansivtwlhqAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGR-----QA 1740
Cdd:PHA03307 158 SPAAVASDAASSRQAAL-------------------PLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSpisasAS 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1741 EGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPP 1820
Cdd:PHA03307 219 SPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSP 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1821 CLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRS-ATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGAL 1899
Cdd:PHA03307 299 SPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGaAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSP 378
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1189438290 1900 PGPGASPVPKTPARTLLAKQHKTQRSPvriPFMQRPARRGPPPLARAVPEPGPRGRAGTEAG 1961
Cdd:PHA03307 379 AASAGRPTRRRARAAVAGRARRRDATG---RFPAGRPRPSPLDAGAASGAFYARYPLLTPSG 437
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1855-2218 |
2.02e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.98 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1855 SQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRP-PVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQ 1933
Cdd:PRK07764 396 AAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPaPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPE 475
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1934 RPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGR---------LGLV--RVASALSSGSESSDRSGFRRQ-LTFIKESP 2001
Cdd:PRK07764 476 PTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAtlrerwpeiLAAVpkRSRKTWAILLPEATVLGVRGDtLVLGFSTG 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2002 GLRRR--------------RSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELR-AAPRQGPAPARQRPPAARPS 2066
Cdd:PRK07764 556 GLARRfaspgnaevlvtalAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARpAAPAAPAAPAAPAPAGAAAA 635
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2067 PGERPARRTTSESPSRLPVRAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAARRSSDGEPRPLPRVAAPGTTWR 2146
Cdd:PRK07764 636 PAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQAD 715
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1189438290 2147 RIRDEDVPHILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPA 2218
Cdd:PRK07764 716 DPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1559-1964 |
2.93e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.60 E-value: 2.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1559 PPARTQPSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEEllqrcissalPR 1638
Cdd:PRK07764 398 APSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ----------PA 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1639 RRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLDSVE--WRAIQE--GANSIVTWLHQAAAATREASSESD 1714
Cdd:PRK07764 468 PAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRerWPEILAavPKRSRKTWAILLPEATVLGVRGDT 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1715 SILSFVSGLSVGSTLQPPKHRKGRQA-EGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAvlrgrtvi 1793
Cdd:PRK07764 548 LVLGFSTGGLARRFASPGNAEVLVTAlAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPA-------- 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1794 yVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSS 1873
Cdd:PRK07764 620 -APAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1874 SSSQTSPASQPLPRKR-------PPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPvriPFMQRPARRGPPPLARA 1946
Cdd:PRK07764 699 AQPAPAPAATPPAGQAddpaaqpPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQP---PPPPAPAPAAAPAAAPP 775
|
410
....*....|....*...
gi 1189438290 1947 VPEPGPRGRAGTEAGPGA 1964
Cdd:PRK07764 776 PSPPSEEEEMAEDDAPSM 793
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1588-1965 |
3.24e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 3.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1588 PEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCIS-------SALPRRRPPVSGLRRRKPRATRLDERP 1660
Cdd:PRK07764 410 PAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSpppaaapSAQPAPAPAAAPEPTAAPAPAPPAAPA 489
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1661 AEGSRERGEEAAGSDRASDLDSVE--WRAIQE--GANSIVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRK 1736
Cdd:PRK07764 490 PAAAPAAPAAPAAPAGADDAATLRerWPEILAavPKRSRKTWAILLPEATVLGVRGDTLVLGFSTGGLARRFASPGNAEV 569
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1737 GRQA-EGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVlrgrtviyvPSPAPRAQPKGTPGPRATPR 1815
Cdd:PRK07764 570 LVTAlAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAA---------PAAPAAPAPAGAAAAPAEAS 640
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1816 KVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARlaktpsssssqtspASQPLPRKRPPVTQA 1895
Cdd:PRK07764 641 AAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPA--------------APAGAAPAQPAPAPA 706
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1896 AGALPGPGASPVPKTPARTllakQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGAR 1965
Cdd:PRK07764 707 ATPPAGQADDPAAQPPQAA----QGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAA 772
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1796-2218 |
3.44e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 3.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1796 PSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPakvPSPGQQRSRSLHRPAKTSELATLSQPPRSATP-PARLAKTPSSS 1874
Cdd:PRK07764 402 AAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPA---PAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPaPAPAAAPEPTA 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1875 SSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQHKtqRSPVRIPFMQRPAR----RGP--------PP 1942
Cdd:PRK07764 479 APAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPEILAAVPK--RSRKTWAILLPEATvlgvRGDtlvlgfstGG 556
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1943 LARAVPEPGprgraGTEAGPGARGGRLGlVRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASAPQG 2022
Cdd:PRK07764 557 LARRFASPG-----NAEVLVTALAEELG-GDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPA 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2023 ASPRRGRPALPavflcssrceelrAAPRQGPAPARQRPPAARPSPGERParrttSESPSRLPVRAPAARPETVkryASLP 2102
Cdd:PRK07764 631 GAAAAPAEASA-------------APAPGVAAPEHHPKHVAVPDASDGG-----DGWPAKAGGAAPAAPPPAP---APAA 689
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2103 HISVARRPDGAVPAAPASADAARRSSDGEPRPlPRVAAPGTTWRRIRDEDVP-HILRSTLPATALPLRGSTPEDAPAGPP 2181
Cdd:PRK07764 690 PAAPAGAAPAQPAPAPAATPPAGQADDPAAQP-PQAAQGASAPSPAADDPVPlPPEPDDPPDPAGAPAQPPPPPAPAPAA 768
|
410 420 430
....*....|....*....|....*....|....*..
gi 1189438290 2182 PRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPA 2218
Cdd:PRK07764 769 APAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVA 805
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1762-2219 |
4.71e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.01 E-value: 4.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1762 GSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRS 1841
Cdd:PHA03307 25 PATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREG 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1842 LHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPArtllakqhk 1921
Cdd:PHA03307 105 SPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP--------- 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1922 tqrspvrIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGArggrlgLVRVASALSSGSESSDRSGFRRQLTFIKESP 2001
Cdd:PHA03307 176 -------LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSS------PISASASSPAPAPGRSAADDAGASSSDSSSS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2002 GLRRRRSELSSAESAASAPQGASPRRGRPALPAVflcSSRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPS 2081
Cdd:PHA03307 243 ESSGCGWGPENECPLPRPAPITLPTRIWEASGWN---GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2082 RLP---VRAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHILR 2158
Cdd:PHA03307 320 SSRessSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRAR 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1189438290 2159 stlpatalplRGSTPEDAPAGPPPRKTSDAvvqteevaapktnSSTSPSLETREPPGAPAG 2219
Cdd:PHA03307 400 ----------RRDATGRFPAGRPRPSPLDA-------------GAASGAFYARYPLLTPSG 437
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2001-2226 |
4.84e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 4.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2001 PGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSP----GERPARRTT 2076
Cdd:PHA03247 258 PPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPPPAPAGDAeeedDEDGAMEVV 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2077 SESP---SRLPVRAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAAR-------RSSDGEPRPLPRVAAPGTTwr 2146
Cdd:PHA03247 338 SPLPrprQHYPLGFPKRRRPTWTPPSSLEDLSAGRHHPKRASLPTRKRRSARhaatpfaRGPGGDDQTRPAAPVPASV-- 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2147 riRDEDVPHILRSTLPATALPLRGSTPeDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLET---REPPGAPAGGQLS 2223
Cdd:PHA03247 416 --PTPAPTPVPASAPPPPATPLPSAEP-GSDDGPAPPPERQPPAPATEPAPDDPDDATRKALDAlreRRPPEPPGADLAE 492
|
...
gi 1189438290 2224 LLG 2226
Cdd:PHA03247 493 LLG 495
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1763-1970 |
5.57e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 48.33 E-value: 5.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1763 SPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPrAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSL 1842
Cdd:PRK12323 373 GPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAP-AAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1843 HRPAKTSELATLSQPPRSATPPArlAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAkqhKT 1922
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAA--AAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAE---SI 526
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1189438290 1923 QRSPVRIPFMQRPARRGPPPLAravpePGPRGRAGTEAGPGARGGRLG 1970
Cdd:PRK12323 527 PDPATADPDDAFETLAPAPAAA-----PAPRAAAATEPVVAPRPPRAS 569
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2022-2299 |
7.06e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.06 E-value: 7.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2022 GASPRRGRPALPAVflcSSRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKRYASL 2101
Cdd:PRK07764 395 AAAAPSAAAAAPAA---APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPA 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2102 PHISVARRPDGAVPAAPASADAARRSSDGEPRPLPR-VAAPGTTWRRIRdEDVPHILRSTLP-----ATALPLRGST--- 2172
Cdd:PRK07764 472 AAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADdAATLRERWPEIL-AAVPKRSRKTWAillpeATVLGVRGDTlvl 550
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2173 ---------------------------------------PEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREP 2213
Cdd:PRK07764 551 gfstgglarrfaspgnaevlvtalaeelggdwqveavvgPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPA 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2214 PGAPAGGqlsllgsdvdGPSLAKAPISAPFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSPmvVAATTDSAAEKAP 2293
Cdd:PRK07764 631 GAAAAPA----------EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAP--APAAPAAPAGAAP 698
|
....*.
gi 1189438290 2294 ATASAT 2299
Cdd:PRK07764 699 AQPAPA 704
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
1622-1865 |
1.96e-04 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 46.78 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1622 RAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSivtwlHQ 1701
Cdd:PLN03237 1174 KAEEAREKLQRAAARGESGAAKKVSRQAPKKPAPKKTTKKASESETTEETYGSSAMETENVAEVVKPKGRAGA-----KK 1248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1702 AAAATREASSESDSILSFvsglsvgstlqppkhrKGRQAEGEMGSArrPEKRGAasvKTSGSPRSPAGPEKPRGTQKTTP 1781
Cdd:PLN03237 1249 KAPAAAKEKEEEDEILDL----------------KDRLAAYNLDSA--PAQSAK---MEETVKAVPARRAAARKKPLASV 1307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1782 GVPAVLRGRTVIYVP--SPAPRAQPKGTPGPRATPRKVA-PPCLAQPAAPAKVPSPGQQRSRSLhRPAKTSELATLSQPP 1858
Cdd:PLN03237 1308 SVISDSDDDDDDFAVevSLAERLKKKGGRKPAAANKKAAkPPAAAKKRGPATVQSGQKLLTEML-KPAEAIGISPEKKVR 1386
|
....*..
gi 1189438290 1859 RSATPPA 1865
Cdd:PLN03237 1387 KMRASPF 1393
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1513-1911 |
3.41e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.93 E-value: 3.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1513 SDEEPPAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETPPCYSLSSSASSLSEPEPSE 1592
Cdd:PHA03307 62 CDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1593 PPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAeellqRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAA 1672
Cdd:PHA03307 142 GSPGPPPAASPPAAGASPAAVASDAASSRQAA-----LPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISAS 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1673 GSDRASDLDSvewraiqegansivtwlHQAAAATREASSESDSILSFVSGLSVGSTLQP---PKHRKGRQAEGEMGSARR 1749
Cdd:PHA03307 217 ASSPAPAPGR-----------------SAADDAGASSSDSSSSESSGCGWGPENECPLPrpaPITLPTRIWEASGWNGPS 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1750 PEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGR-TVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAP 1828
Cdd:PHA03307 280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSsRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPP 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1829 AKVPSPgqQRSRSLHRPAKTSelatlSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVP 1908
Cdd:PHA03307 360 ADPSSP--RKRPRPSRAPSSP-----AASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPL 432
|
...
gi 1189438290 1909 KTP 1911
Cdd:PHA03307 433 LTP 435
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1744-2108 |
4.94e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.55 E-value: 4.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1744 MGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLrgrtviyvPSPAPRAQPKGTPGPRATPRKVAPPCLA 1823
Cdd:PHA03307 55 VVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA--------SPAREGSPTPPGPSSPDPPPPTPPPASP 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1824 QPAAPAKVPSPgQQRSRSLHRPAKTSELATLSQPPRSATPPARlAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPG 1903
Cdd:PHA03307 127 PPSPAPDLSEM-LRPVGSPGPPPAASPPAAGASPAAVASDAAS-SRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASP 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1904 ASPVPKTPARTllakqhkTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRLGLVRVASALSSGSE 1983
Cdd:PHA03307 205 RPPRRSSPISA-------SASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNG 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1984 SSDRSGFRRQLTfikeSPGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPARQRPPA- 2062
Cdd:PHA03307 278 PSSRPGPASSSS----SPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSp 353
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1189438290 2063 ARPSPGERPARRTTSESPSRLPV--RAPAARPETVKRYASLPHISVAR 2108
Cdd:PHA03307 354 SRPPPPADPSSPRKRPRPSRAPSspAASAGRPTRRRARAAVAGRARRR 401
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1516-1918 |
5.11e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 5.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1516 EPPAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPsliADETPPCYSLSSSASSLSEPEPSEPPA 1595
Cdd:PRK07764 410 PAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPA---AAPSAQPAPAPAAAPEPTAAPAPAPPA 486
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1596 VHPRGREPAVTKDPGPGGGRDSSPSPRAA-EELLQrcissALPRRRPPVSGLRRRKPRATRLDER------PAEGSRERg 1668
Cdd:PRK07764 487 APAPAAAPAAPAAPAAPAGADDAATLRERwPEILA-----AVPKRSRKTWAILLPEATVLGVRGDtlvlgfSTGGLARR- 560
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1669 eeAAGSDRASDLDSV-------EWRAIQEGANSivtwlhqAAAATREASSESDSILSFVSGL---SVGSTLQPPKHRKGR 1738
Cdd:PRK07764 561 --FASPGNAEVLVTAlaeelggDWQVEAVVGPA-------PGAAGGEGPPAPASSGPPEEAArpaAPAAPAAPAAPAPAG 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1739 QAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVA 1818
Cdd:PRK07764 632 AAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPA 711
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1819 PPCLAQPAAPAKVPSPGQQRSRSLHRPAktSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGA 1898
Cdd:PRK07764 712 GQADDPAAQPPQAAQGASAPSPAADDPV--PLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDD 789
|
410 420
....*....|....*....|..
gi 1189438290 1899 LPGPGASPV--PKTPARTLLAK 1918
Cdd:PRK07764 790 APSMDDEDRrdAEEVAMELLEE 811
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1517-1912 |
5.29e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 5.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1517 PPAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAApPPARTQPSLI--------ADETPPCYSLSSSASSLSEP 1588
Cdd:PRK07764 401 AAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAP-PSPAGNAPAGgapspppaAAPSAQPAPAPAAAPEPTAA 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1589 EPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAA-EELLQrcissALPRRRPPVSGLRRRKPRATRLDER------PA 1661
Cdd:PRK07764 480 PAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERwPEILA-----AVPKRSRKTWAILLPEATVLGVRGDtlvlgfST 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1662 EGSRERgeeaagsdrasdldsvewRAIQEGANSIVTWLHQaaaatreassesdsilsfVSGLSVGSTLQPPKHRKGRQAE 1741
Cdd:PRK07764 555 GGLARR------------------FASPGNAEVLVTALAE------------------ELGGDWQVEAVVGPAPGAAGGE 598
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1742 GEMGSARRPEKRGAASVKTSGSPRSPAGPekPRGTQKTTPGVPAVLRGRTVIYVP-SPAPRAQPKGTPGPRATPRKVAPP 1820
Cdd:PRK07764 599 GPPAPASSGPPEEAARPAAPAAPAAPAAP--APAGAAAAPAEASAAPAPGVAAPEhHPKHVAVPDASDGGDGWPAKAGGA 676
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1821 CLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALP 1900
Cdd:PRK07764 677 APAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPA 756
|
410
....*....|..
gi 1189438290 1901 GPGASPVPKTPA 1912
Cdd:PRK07764 757 QPPPPPAPAPAA 768
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1721-2150 |
6.43e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.98 E-value: 6.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1721 SGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAP 1800
Cdd:PRK07764 383 RRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAP 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1801 RAQPkgTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQrsrslhRPAKTSELATLSQPPRSATPPAR--LAKTPSSSSSQT 1878
Cdd:PRK07764 463 SAQP--APAPAAAPEPTAAPAPAPPAAPAPAAAPAAP------AAPAAPAGADDAATLRERWPEILaaVPKRSRKTWAIL 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1879 SPASQPLPRKRPPVTQA------AGALPGPGASPVPKTPARTLLAKQHK------TQRSPVRIPFMQRPARRGPPP-LAR 1945
Cdd:PRK07764 535 LPEATVLGVRGDTLVLGfstgglARRFASPGNAEVLVTALAEELGGDWQveavvgPAPGAAGGEGPPAPASSGPPEeAAR 614
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1946 AVPEPGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFrrqlTFIKESPGLRRRRSELSSAESAASAPQGASP 2025
Cdd:PRK07764 615 PAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAV----PDASDGGDGWPAKAGGAAPAAPPPAPAPAAP 690
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2026 RRGRPALPAvflcssrceELRAAPRQGPAPAR-QRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKRYASLPHI 2104
Cdd:PRK07764 691 AAPAGAAPA---------QPAPAPAATPPAGQaDDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPP 761
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1189438290 2105 SVARRPDGavpaapaSADAARRSSDGEPRPLPRVAAPGTTWRRIRD 2150
Cdd:PRK07764 762 PAPAPAAA-------PAAAPPPSPPSEEEEMAEDDAPSMDDEDRRD 800
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1412-1630 |
7.36e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.98 E-value: 7.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1412 GPPRDQPGGPAGRQRPTGRPTSARQAMG--HRHKAGGAGRSAEQSRGAGKNRAGLELPLGRPPSAPADKDGSKPGRTRGD 1489
Cdd:PRK07764 596 GGEGPPAPASSGPPEEAARPAAPAAPAApaAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1490 GALqslclTTPTEEAVYCFYGNDSDEEPPAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIA 1569
Cdd:PRK07764 676 AAP-----AAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPD 750
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1189438290 1570 DETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQR 1630
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAMELLEE 811
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1371-1944 |
7.78e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.93 E-value: 7.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1371 PVYMLVPAPAPAQEDDSCTDSAEGT----PVNFSSAASLSDETLQGPPRdQPGGPAGRQRPTGRPTSARQAMGHRHKAGG 1446
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPrpsePAVTSRARRPDAPPQSARPR-APVDDRGDPRGPAPPSPLPPDTHAPDPPPP 2629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1447 AGRSAEQSRGAGKNRAGLELPLGRPPSAPADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSD-EEPPAAAPTPT 1525
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSlADPPPPPPTPE 2709
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1526 HRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPArTQPSLIADETPPcyslsSSASSLSEPEPSEPPAVHPRGREPAV 1605
Cdd:PHA03247 2710 PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVP-AGPATPGGPARP-----ARPPTTAGPPAPAPPAAPAAGPPRRL 2783
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1606 TKDPGP--GGGRDSSPSPR--AAEELLQRCISSALPRRRPPVSGLrRRKPRATRLDERPAEGSRERGEEAAGSdrasdld 1681
Cdd:PHA03247 2784 TRPAVAslSESRESLPSPWdpADPPAAVLAPAAALPPAASPAGPL-PPPTSAQPTAPPPPPGPPPPSLPLGGS------- 2855
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1682 svewraIQEGANSIVTWLHQAAAATREASSESdsilsfvsglSVGSTLQPPKHRKGR-QAEGEMGSARRPEKRGAASVKT 1760
Cdd:PHA03247 2856 ------VAPGGDVRRRPPSRSPAAKPAAPARP----------PVRRLARPAVSRSTEsFALPPDQPERPPQPQAPPPPQP 2919
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1761 SGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKG--TPGPRATPRKVAPpclaQPAAPAKVPSPGQQR 1838
Cdd:PHA03247 2920 QPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGalVPGRVAVPRFRVP----QPAPSREAPASSTPP 2995
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1839 SRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPV--TQAAGALPGPGASPVPKTPARTLL 1916
Cdd:PHA03247 2996 LTGHSLSRVSSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERsdLEALDPLPPEPHDPFAHEPDPATP 3075
|
570 580
....*....|....*....|....*...
gi 1189438290 1917 AKQHKTQRSpvripfmqrpARRGPPPLA 1944
Cdd:PHA03247 3076 EAGARESPS----------SQFGPPPLS 3093
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1857-2264 |
1.11e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.39 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1857 PPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTllakqhktqrSPVRIPFMQRPA 1936
Cdd:PHA03307 72 PPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPS----------PAPDLSEMLRPV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1937 RRGPPPLARAVPEPGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESA 2016
Cdd:PHA03307 142 GSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2017 ASAPQGASPRRGRPALPAVFLCSSRCEE--LRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRlPVRAPAARPEt 2094
Cdd:PHA03307 222 PAPGRSAADDAGASSSDSSSSESSGCGWgpENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSS-SPRERSPSPS- 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2095 vkryaslphisvarrpdgavpaapasadaarrSSDGEPRPLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLrGSTPE 2174
Cdd:PHA03307 300 --------------------------------PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAV-SPGPS 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2175 DAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAGGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGG 2254
Cdd:PHA03307 347 PSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
|
410
....*....|
gi 1189438290 2255 FPASRHGSPS 2264
Cdd:PHA03307 427 YARYPLLTPS 436
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1602-1864 |
1.20e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.07 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1602 EPAVTKDPGPGGGRDSSPsPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLD 1681
Cdd:PRK07003 359 EPAVTGGGAPGGGVPARV-AGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATAD 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1682 SVEwRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTS 1761
Cdd:PRK07003 438 RGD-DAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAA 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1762 GSPRSPAGPEKPrgTQKTTPGVPA----------------VLR--GRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPcla 1823
Cdd:PRK07003 517 SREDAPAAAAPP--APEARPPTPAaaapaaraggaaaaldVLRnaGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPR--- 591
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1189438290 1824 qPAAPakVPSPGQQRSRSLHRPAKTSElATLSQPPRSATPP 1864
Cdd:PRK07003 592 -VAVQ--VPTPRARAATGDAPPNGAAR-AEQAAESRGAPPP 628
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1765-1913 |
1.45e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.93 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1765 RSPAGPEKPRGTQKTTPGVPAVLRgrtviyvPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAkvpspgqqrsrslhr 1844
Cdd:PRK14951 365 KPAAAAEAAAPAEKKTPARPEAAA-------PAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAP--------------- 422
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1845 PAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRP-PVTQAAGALPGPGASPVPKTPAR 1913
Cdd:PRK14951 423 PAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPePAVASAAPAPAAAPAAARLTPTE 492
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2047-2300 |
1.52e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 43.71 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2047 AAPRQGPAPARQRPPAARPSPGERPArrttseSPSRLPVRAPAARPEtvkryaslphISVARRPDGAVPAAPASADAARR 2126
Cdd:PRK12323 379 AAPVAQPAPAAAAPAAAAPAPAAPPA------APAAAPAAAAAARAV----------AAAPARRSPAPEALAAARQASAR 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2127 SSDGEPRPLPRVAApgttwrrirdedvphilrstLPATALPlrgstPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSP 2206
Cdd:PRK12323 443 GPGGAPAPAPAPAA--------------------APAAAAR-----PAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2207 SLEtrEPPGAPaggqlsllgsdvdgPSLAKAPISAPFvhEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSPMVVAATTD 2286
Cdd:PRK12323 498 PWE--ELPPEF--------------ASPAPAQPDAAP--AGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEP 559
|
250
....*....|....
gi 1189438290 2287 SAAEKAPATASATL 2300
Cdd:PRK12323 560 VVAPRPPRASASGL 573
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
1731-1968 |
1.63e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.90 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1731 PPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGP 1810
Cdd:PHA03378 529 PPQPRAGRRAPCVYTEDLDIESDEPASTEPVHDQLLPAPGLGPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEP 608
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1811 RAT---------PRKVAPPCLAQPAAPAKVpSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPA 1881
Cdd:PHA03378 609 PTTqshipetsaPRQWPMPLRPIPMRPLRM-QPITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQPSPTGANTMLPI 687
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1882 SQPLPRKRPPvTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAG 1961
Cdd:PHA03378 688 QWAPGTMQPP-PRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARP 766
|
....*..
gi 1189438290 1962 PGARGGR 1968
Cdd:PHA03378 767 PAAAPGA 773
|
|
| SAMP |
pfam05924 |
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1620-1641 |
1.77e-03 |
|
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). This motif binds axin.
Pssm-ID: 461782 Cd Length: 22 Bit Score: 37.57 E-value: 1.77e-03
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1385-1407 |
2.24e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.24e-03
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1259-1280 |
2.38e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.38e-03
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1716-1914 |
2.51e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.94 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1716 ILSFVSGLSVGSTlQPPKHRKGRQAEgEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGV--PAVLRGRTVI 1793
Cdd:PRK12323 360 MLAFRPGQSGGGA-GPATAAAAPVAQ-PAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARrsPAPEALAAAR 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1794 YVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSrslhRPAKTSELATLSQPPRSATPPARLA---KT 1870
Cdd:PRK12323 438 QASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARA----APAAAPAPADDDPPPWEELPPEFASpapAQ 513
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1189438290 1871 PSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPART 1914
Cdd:PRK12323 514 PDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAAT 557
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1747-1960 |
2.80e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.91 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1747 ARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVlrgrtviyvpspAPRAQPKGTPGPRATPRKVAPPCLAQPA 1826
Cdd:PRK07003 357 AFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAV------------PAVTAVTGAAGAALAPKAAAAAAATRAE 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1827 APAKVPSPGQQRSRSlhrpaktsELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASP 1906
Cdd:PRK07003 425 APPAAPAPPATADRG--------DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRA 496
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1189438290 1907 VPKTPArtlLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPG---PRGRAGTEA 1960
Cdd:PRK07003 497 AAPSAA---TPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAaaaPAARAGGAA 550
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2047-2298 |
6.64e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 6.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2047 AAPRQGPAPARQRPPAARPSPGerPARRTTSESPSRLPVRAPAARPEtvkryaslphiSVARRPDGAVPAAPASADAARR 2126
Cdd:PRK07764 392 GAPAAAAPSAAAAAPAAAPAPA--AAAPAAAAAPAPAAAPQPAPAPA-----------PAPAPPSPAGNAPAGGAPSPPP 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2127 SSDGEPRPLPRVAAPgttwrrirdedvPHILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEV------AAPKT 2200
Cdd:PRK07764 459 AAAPSAQPAPAPAAA------------PEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERwpeilaAVPKR 526
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2201 NSSTSPSLETREPPGAPAGGQLSLlgsDVDGPSLAK-------APISAPFVHEGLG-------VAVGGFPASRHGSPSRS 2266
Cdd:PRK07764 527 SRKTWAILLPEATVLGVRGDTLVL---GFSTGGLARrfaspgnAEVLVTALAEELGgdwqveaVVGPAPGAAGGEGPPAP 603
|
250 260 270
....*....|....*....|....*....|..
gi 1189438290 2267 ARVPPFNYVPSPMVVAATTDSAAEKAPATASA 2298
Cdd:PRK07764 604 ASSGPPEEAARPAAPAAPAAPAAPAPAGAAAA 635
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
1767-1957 |
7.31e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 41.59 E-value: 7.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1767 PAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPA 1846
Cdd:PHA03378 670 GHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAA 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1847 KTSELATLSQPPRSATPPArlaKTPSSSSSQTSPASQPLPRKRPPvtqaagalPGPGASPVPKTP--ARTLLAKQHKTQR 1924
Cdd:PHA03378 750 APGRARPPAAAPGRARPPA---AAPGAPTPQPPPQAPPAPQQRPR--------GAPTPQPPPQAGptSMQLMPRAAPGQQ 818
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1189438290 1925 SPVRIPFMQ---------RPARRGPPPLAR---AVPEPGPRGRAG 1957
Cdd:PHA03378 819 GPTKQILRQlltggvkrgRPSLKKPAALERqaaAGPTPSPGSGTS 863
|
|
| PHA03309 |
PHA03309 |
transcriptional regulator ICP4; Provisional |
1618-1959 |
8.48e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 165564 [Multi-domain] Cd Length: 2033 Bit Score: 41.76 E-value: 8.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1618 SPSPR-AAEELLQR----------------CISSALPRRRPPVSglRRRKPRATRLDERPAEGSRERGEEAAGSdRASDL 1680
Cdd:PHA03309 1715 SPSPRdVALRLLERqqelnrqlllelrrgsCEISPSPRRRDAEG--RRFGCRQDDDDGYDYEGGRESPERVLGR-RQSRR 1791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1681 DSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSfvsglsvgstlqPPKHRKGRQAEGEMGSARRPEKRGAASvkt 1760
Cdd:PHA03309 1792 DSVPVRRRSGAANCGGRWMISAGRSSSSSSSSSSSSSS------------SPSSRPSRSATPSLSPSPSPPRRAPVD--- 1856
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1761 sgspRSPAGPEKPRGTQKTTPGvpavlrgrtviyvpSPAPRAQPKGTPGPRATPRKVAPPCLAQpaapakvpspGQQRSR 1840
Cdd:PHA03309 1857 ----RSRSGRRRERDRPSANPF--------------RWAPRQRSRADHSPDGTAPGDAPLNLED----------GPGRGR 1908
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 1841 SLHRPAKTSELATLSQPPRS--------ATPPARLAKTPSSSSSQTSPASQPLPR-KRPPVTQAAGALPGPGA-SPVPKT 1910
Cdd:PHA03309 1909 PIWTPSSATTLPSRSGPEDSvdetetedSAPPARLAPSPLETSRAEDSEDSEYPEySNPRLGKSPPALKSREArRPSSKQ 1988
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1189438290 1911 PARTLLAKQHKTQRSPVRIPFMQRPArrgppPLARAVPEPGPRGRAGTE 1959
Cdd:PHA03309 1989 PRRPSSGKNGHTDVSAASAFFLGRPA-----PGSCGRRPLGARVRGGTE 2032
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2020-2235 |
9.35e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.01 E-value: 9.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2020 PQGASPRRGR-PALPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSPGERPArrttsespsrlPVRAPAARPETVKRY 2098
Cdd:PRK12323 392 PAAAAPAPAApPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPG-----------GAPAPAPAPAAAPAA 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438290 2099 ASLPHISVARRPdgavpAAPASADAARRSSDGEPRPLPRVAAPgttWRRIRDEDVPHILRSTLPATALPLRGSTPEDAPA 2178
Cdd:PRK12323 461 AARPAAAGPRPV-----AAAAAAAPARAAPAAAPAPADDDPPP---WEELPPEFASPAPAQPDAAPAGWVAESIPDPATA 532
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1189438290 2179 GPPPRKTSDAVVQTEEVAAPKTNSStspslETREPPGAPAGGQLSLLG-SDVDGPSLA 2235
Cdd:PRK12323 533 DPDDAFETLAPAPAAAPAPRAAAAT-----EPVVAPRPPRASASGLPDmFDGDWPALA 585
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
524-561 |
9.38e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.38e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1189438290 524 KKVLREAGSVTALVQCvLRATKESTLKSVLSALWNLSA 561
Cdd:pfam00514 5 KQAVIEAGAVPPLVRL-LSSPDEEVQEEAAWALSNLAA 41
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
660-695 |
9.76e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.76e-03
10 20 30
....*....|....*....|....*....|....*.
gi 1189438290 660 ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA 695
Cdd:pfam00514 6 QAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| |
