|
Name |
Accession |
Description |
Interval |
E-value |
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
1-887 |
0e+00 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 1325.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 1 MFEKFTEGAIKVIMLAQEESRRMGHNFVGTEQVLLGILGQRHGIAGRALAQLNVTLKKTRKEVEKYIGRGTGFVASEIPF 80
Cdd:CHL00095 1 MFERFTEKAIKVIMLSQEEARRLGHNFVGTEQILLGLIGEGTGIAARALKSMGVTLKDARIEVEKIIGRGTGFVAVEIPF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 81 TPRAKRVLEMSIHEAQDLGVNYVGTEHILLSLLNEADGIALRTLDRLRVNIPKLRHLIFTYIEEQQEDILKPplsdqekw 160
Cdd:CHL00095 81 TPRAKRVLEMSLEEARDLGHNYIGTEHLLLALLEEGEGVAARVLENLGVDLSKIRSLILNLIGEIIEAILGA-------- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 161 llsreKGNKWTTSTLENYSENITQEALDKRLDPVIGRNEEINALVKVLGRRRKNNPVLVGEAGVGKTACAEGLALLMVSG 240
Cdd:CHL00095 153 -----EQSRSKTPTLEEFGTNLTKEAIDGNLDPVIGREKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRIVNR 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 241 ECPEFLDNHAVLCLDLGSVLAGTKYRGEFEERMKTIIEDVQKNGKIILVIDEIHTIVGAGAAEGAVDAANLLKPALARGT 320
Cdd:CHL00095 228 DVPDILEDKLVITLDIGLLLAGTKYRGEFEERLKRIFDEIQENNNIILVIDEVHTLIGAGAAEGAIDAANILKPALARGE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 321 LRLIGATTLDEYRKYIEKDPALERRFHSIVVEEPTVEVTIDILNGLRPEFQRHHALTYSSDSLTAAAQLASRFITDRNLP 400
Cdd:CHL00095 308 LQCIGATTLDEYRKHIEKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEKHHNLSISDKALEAAAKLSDQYIADRFLP 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 401 DKAIDVIDEAGSRVRLRNRLLPIGIQKLLIELHDTLKDIDEAVRTHDFNTAKLLLDHEVEVRTHLRIMKYALASKDEyrk 480
Cdd:CHL00095 388 DKAIDLLDEAGSRVRLINSRLPPAARELDKELREILKDKDEAIREQDFETAKQLRDREMEVRAQIAAIIQSKKTEEE--- 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 481 KMVTFDRVLEQDVTEVVSAWTGVPVTKINESENERLKKMEDILHERLIGQHHAIVAVSKAVRRARVGIQDPKRPIASFIF 560
Cdd:CHL00095 465 KRLEVPVVTEEDIAEIVSAWTGIPVNKLTKSESEKLLHMEETLHKRIIGQDEAVVAVSKAIRRARVGLKNPNRPIASFLF 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 561 AGPTGVGKTELTKALAEYIFDTEKNMIRFDMSEFMERHTVAKLIGSPPGYVGHEDGGQLTDAVRRKPYSIVLFDEVEKAH 640
Cdd:CHL00095 545 SGPTGVGKTELTKALASYFFGSEDAMIRLDMSEYMEKHTVSKLIGSPPGYVGYNEGGQLTEAVRKKPYTVVLFDEIEKAH 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 641 PDVFNLFLQILDDGHLSDSKGRLISFKNCIIVMTTNLGARVIERESpilpkSKMGFnrryeetkeqresrkievmvntdg 720
Cdd:CHL00095 625 PDIFNLLLQILDDGRLTDSKGRTIDFKNTLIIMTSNLGSKVIETNS-----GGLGF------------------------ 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 721 tfllkppvKKEVNADDEKKFATISALVQEELKKFFRPEFLNRIDDIIVFNHLSKHDIWEICGILLKGLGKRLGEQGATLS 800
Cdd:CHL00095 676 --------ELSENQLSEKQYKRLSNLVNEELKQFFRPEFLNRLDEIIVFRQLTKNDVWEIAEIMLKNLFKRLNEQGIQLE 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 801 VDNAVQYYLTEEGYDPVYGARPLRRAITKLLEDRLAMACLDNPIQPGTHINITQQikpytttystvfeDLYTTEILIEFD 880
Cdd:CHL00095 748 VTERIKTLLIEEGYNPLYGARPLRRAIMRLLEDPLAEEVLSFKIKPGDIIIVDVN-------------DEKEVKILLINK 814
|
....*..
gi 118411220 881 NSNVKRP 887
Cdd:CHL00095 815 DNLILNK 821
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1-853 |
0e+00 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 1104.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 1 MFEKFTEGAIKVIMLAQEESRRMGHNFVGTEQVLLGILGQRHGIAGRALAQLNVTLKKTRKEVEKYIGRGTGF--VASEI 78
Cdd:COG0542 2 NFEKFTEKAQEALEAAQELARRLGHQEVEPEHLLLALLEQGEGLAAKLLRKLGVDLDALREELEEALGRLPKVsgSSGQP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 79 PFTPRAKRVLEMSIHEAQDLGVNYVGTEHILLSLLNEADGIALRTLDRLRVNIPKLRHLIFTYIEEQQEDilkpplsdqe 158
Cdd:COG0542 82 YLSPRLKRVLELAELEARKLGDEYISTEHLLLALLREGEGVAARILKKLGITLEALREALEELRGGSRVT---------- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 159 kwllsrEKGNKWTTSTLENYSENITQEALDKRLDPVIGRNEEINALVKVLGRRRKNNPVLVGEAGVGKTACAEGLALLMV 238
Cdd:COG0542 152 ------SQNPESKTPALDKYGRDLTELAREGKLDPVIGRDEEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 239 SGECPEFLDNHAVLCLDLGSVLAGTKYRGEFEERMKTIIEDVQK-NGKIILVIDEIHTIVGAGAAEGAVDAANLLKPALA 317
Cdd:COG0542 226 NGDVPESLKDKRVLSLDLGALVAGAKYRGEFEERLKAVLDEVKKsEGNIILFIDELHTLVGAGGAEGAMDAANLLKPALA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 318 RGTLRLIGATTLDEYRKYIEKDPALERRFHSIVVEEPTVEVTIDILNGLRPEFQRHHALTYSSDSLTAAAQLASRFITDR 397
Cdd:COG0542 306 RGELRCIGATTLDEYRKYIEKDAALERRFQPVLVEEPSVEDTISILRGLKERYEAHHGVRITDEALVAAVRLSDRYITDR 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 398 NLPDKAIDVIDEAGSRVRLRNRLLPIGIQKLLIELHDTLKDIDEAVRTHD---FNTAKLLLDHEVEVRTHLRIMK----- 469
Cdd:COG0542 386 FLPDKAIDLIDEAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDeasFERLAELRDELAELEEELEALKarwea 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 470 ----------------------------YALASKDEYRKKMVTFDRVLEQDVTEVVSAWTGVPVTKINESENERLKKMED 521
Cdd:COG0542 466 ekelieeiqelkeeleqrygkipelekeLAELEEELAELAPLLREEVTEEDIAEVVSRWTGIPVGKLLEGEREKLLNLEE 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 522 ILHERLIGQHHAIVAVSKAVRRARVGIQDPKRPIASFIFAGPTGVGKTELTKALAEYIFDTEKNMIRFDMSEFMERHTVA 601
Cdd:COG0542 546 ELHERVIGQDEAVEAVADAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELAKALAEFLFGDEDALIRIDMSEYMEKHSVS 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 602 KLIGSPPGYVGHEDGGQLTDAVRRKPYSIVLFDEVEKAHPDVFNLFLQILDDGHLSDSKGRLISFKNCIIVMTTNLGARV 681
Cdd:COG0542 626 RLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTIIIMTSNIGSEL 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 682 IERespilpkskmgfnrryeetkeqresrkievmvntdgtfllkppvkkevNADDEKKFATISALVQEELKKFFRPEFLN 761
Cdd:COG0542 706 ILD------------------------------------------------LAEDEPDYEEMKEAVMEELKKHFRPEFLN 737
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 762 RIDDIIVFNHLSKHDIWEICGILLKGLGKRLGEQGATLSVDNAVQYYLTEEGYDPVYGARPLRRAITKLLEDRLAMACLD 841
Cdd:COG0542 738 RIDEIIVFHPLSKEELRKIVDLQLKRLRKRLAERGITLELTDAAKDFLAEKGYDPEYGARPLKRAIQRELEDPLAEEILA 817
|
890
....*....|..
gi 118411220 842 NPIQPGTHINIT 853
Cdd:COG0542 818 GEIKEGDTITVD 829
|
|
| chaperone_ClpB |
TIGR03346 |
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent ... |
5-852 |
0e+00 |
|
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization]
Pssm-ID: 274529 [Multi-domain] Cd Length: 850 Bit Score: 881.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 5 FTEGAIKVIMLAQEESRRMGHNFVGTEQVLLGILGQRHGIAGRALAQLNVTLKKTRKEVEKYIGR-----GTGfvaSEIP 79
Cdd:TIGR03346 1 LTEKFQEALQAAQSLALGRDHQQIEPEHLLKALLDQEGGLARPLLQKAGVNVGALRQALEKELERlpkvsGPG---GQVY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 80 FTPRAKRVLEMSIHEAQDLGVNYVGTEHILLSLLNEAD--GIALR----TLDRLRVNIPKLRhliftyieeqqedilkpp 153
Cdd:TIGR03346 78 LSPDLNRLLNLAEKLAQKRGDEFISSEHLLLALLDDKGtlGKLLKeagaTADALEAAINAVR------------------ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 154 lsdqekwllsreKGNKWTTST-------LENYSENITQEALDKRLDPVIGRNEEINALVKVLGRRRKNNPVLVGEAGVGK 226
Cdd:TIGR03346 140 ------------GGQKVTDANaedqyeaLEKYARDLTERAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGK 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 227 TACAEGLALLMVSGECPEFLDNHAVLCLDLGSVLAGTKYRGEFEERMKTIIEDVQK-NGKIILVIDEIHTIVGAGAAEGA 305
Cdd:TIGR03346 208 TAIVEGLAQRIVNGDVPEGLKNKRLLALDMGALIAGAKYRGEFEERLKAVLNEVTKsEGQIILFIDELHTLVGAGKAEGA 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 306 VDAANLLKPALARGTLRLIGATTLDEYRKYIEKDPALERRFHSIVVEEPTVEVTIDILNGLRPEFQRHHALTYSSDSLTA 385
Cdd:TIGR03346 288 MDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQPVFVDEPSVEDTISILRGLKERYEVHHGVRITDPAIVA 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 386 AAQLASRFITDRNLPDKAIDVIDEAGSRVR------------LRNRLLPIGIQKL-------------LIELHDTLKDID 440
Cdd:TIGR03346 368 AATLSHRYITDRFLPDKAIDLIDEAAARIRmeidskpeeldeLDRRIIQLEIEREalkkekdeaskkrLEDLEKELADLE 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 441 E--AVRTHDFNTAKLLLDHEVEVRTHL-----------RIMKYALASKDEY--------------RKKMVTFDRVLEQDV 493
Cdd:TIGR03346 448 EeyAELEEQWKAEKASIQGIQQIKEEIeqvrleleqaeREGDLAKAAELQYgklpelekqlqaaeQKLGEEQNRLLREEV 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 494 T-----EVVSAWTGVPVTKINESENERLKKMEDILHERLIGQHHAIVAVSKAVRRARVGIQDPKRPIASFIFAGPTGVGK 568
Cdd:TIGR03346 528 TaeeiaEVVSRWTGIPVSKMLEGEREKLLHMEEELHERVVGQDEAVEAVSDAIRRSRAGLSDPNRPIGSFLFLGPTGVGK 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 569 TELTKALAEYIFDTEKNMIRFDMSEFMERHTVAKLIGSPPGYVGHEDGGQLTDAVRRKPYSIVLFDEVEKAHPDVFNLFL 648
Cdd:TIGR03346 608 TELAKALAEFLFDSEDAMVRIDMSEYMEKHSVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEVEKAHPDVFNVLL 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 649 QILDDGHLSDSKGRLISFKNCIIVMTTNLGARVIERespilpkskMGFNRRYEETKEQresrkievmvntdgtfllkppv 728
Cdd:TIGR03346 688 QVLDDGRLTDGQGRTVDFRNTVIIMTSNLGSDFIQE---------LAGGDDYEEMREA---------------------- 736
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 729 kkevnaddekkfatisalVQEELKKFFRPEFLNRIDDIIVFNHLSKHDIWEICGILLKGLGKRLGEQGATLSVDNAVQYY 808
Cdd:TIGR03346 737 ------------------VMEVLRAHFRPEFLNRIDEIVVFHPLGREQIARIVEIQLGRLRKRLAERKITLELSDAALDF 798
|
890 900 910 920
....*....|....*....|....*....|....*....|....
gi 118411220 809 LTEEGYDPVYGARPLRRAITKLLEDRLAMACLDNPIQPGTHINI 852
Cdd:TIGR03346 799 LAEAGYDPVYGARPLKRAIQREIENPLAKKILAGEVAPGDTIRV 842
|
|
| ClpA |
TIGR02639 |
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, ... |
5-836 |
0e+00 |
|
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, peptides, and glycopeptides]
Pssm-ID: 274241 [Multi-domain] Cd Length: 730 Bit Score: 687.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 5 FTEGAIKVIMLAQEESRRMGHNFVGTEQVLLGILGQRHGIAgrALAQLNVTLKKTRKEVEKYIGRGTGFVASEIPFTPRA 84
Cdd:TIGR02639 1 ISEELERILSDALEEAKERRHEFVTLEHLLLALLDDNEAIE--ILEECGGDVELLRKRLEDYLEENLPVIPEDIDEEPEQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 85 ----KRVLEMSIHEAQDLGVNYVGTEHILLSLLNEADGIALRTLDRLRVNIPKLRHLIftyieeqQEDILKPPLSDQEKw 160
Cdd:TIGR02639 79 tvgvQRVIQRALLHVKSAGKKEIDIGDLLVALFDEEDSHASYFLKSQGITRLDILNYI-------SHGISKDDGKDQLG- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 161 lLSREKGNKWTTSTLENYSENITQEALDKRLDPVIGRNEEINALVKVLGRRRKNNPVLVGEAGVGKTACAEGLALLMVSG 240
Cdd:TIGR02639 151 -EEAGKEEEKGQDALEKYTVDLTEKAKNGKIDPLIGREDELERTIQVLCRRKKNNPLLVGEPGVGKTAIVEGLALRIAEG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 241 ECPEFLDNHAVLCLDLGSVLAGTKYRGEFEERMKTIIEDVQKNGKIILVIDEIHTIVGAGA-AEGAVDAANLLKPALARG 319
Cdd:TIGR02639 230 KVPERLKNAKIYSLDMGTLLAGTKYRGDFEERLKAVVSEIEKEPNAILFIDEIHTIVGAGAtSGGSMDASNLLKPALSSG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 320 TLRLIGATTLDEYRKYIEKDPALERRFHSIVVEEPTVEVTIDILNGLRPEFQRHHALTYSSDSLTAAAQLASRFITDRNL 399
Cdd:TIGR02639 310 KIRCIGSTTYEEYKNHFEKDRALSRRFQKIDVGEPSIEETVKILKGLKEQYEEFHHVKYSDEALEAAVELSARYINDRFL 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 400 PDKAIDVIDEAGSRVRLRnrllpigiqkllielhdtlkdideavrthdfntakllldhevevrthlrimkyALASKDEYr 479
Cdd:TIGR02639 390 PDKAIDVIDEAGAAFRLR-----------------------------------------------------PKAKKKAN- 415
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 480 kkmvtfdrVLEQDVTEVVSAWTGVPVTKINESENERLKKMEDILHERLIGQHHAIVAVSKAVRRARVGIQDPKRPIASFI 559
Cdd:TIGR02639 416 --------VNVKDIENVVAKMAKIPVKTVSSDDREQLKNLEKNLKAKIFGQDEAIDQLVSAIKRSRAGLGDPNKPVGSFL 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 560 FAGPTGVGKTELTKALAEYIfdtEKNMIRFDMSEFMERHTVAKLIGSPPGYVGHEDGGQLTDAVRRKPYSIVLFDEVEKA 639
Cdd:TIGR02639 488 FVGPTGVGKTELAKQLAEEL---GVHLLRFDMSEYMEKHTVSRLIGSPPGYVGFEQGGLLTDAVRKHPHCVLLLDEIEKA 564
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 640 HPDVFNLFLQILDDGHLSDSKGRLISFKNCIIVMTTNLGARVIErespilpKSKMGFnrryeeTKEQRESRkievmvntd 719
Cdd:TIGR02639 565 HPDIYNILLQVMDYATLTDNNGRKADFRNVILIMTSNAGASEMS-------KPPIGF------GGENRESK--------- 622
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 720 gtfllkppvkkevnaddekkfatisalVQEELKKFFRPEFLNRIDDIIVFNHLSKHDIWEICGILLKGLGKRLGEQGATL 799
Cdd:TIGR02639 623 ---------------------------SLKAIKKLFSPEFRNRLDAIIHFNDLSEEMAEKIVKKFLDELQDQLNEKNIEL 675
|
810 820 830
....*....|....*....|....*....|....*..
gi 118411220 800 SVDNAVQYYLTEEGYDPVYGARPLRRAITKLLEDRLA 836
Cdd:TIGR02639 676 ELTDDAKKYLAEKGYDEEFGARPLARVIQEEIKKPLS 712
|
|
| PRK10865 |
PRK10865 |
ATP-dependent chaperone ClpB; |
15-850 |
0e+00 |
|
ATP-dependent chaperone ClpB;
Pssm-ID: 182791 [Multi-domain] Cd Length: 857 Bit Score: 653.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 15 LAQEESRRMGHN--FVGTEQVLLGILGQRHGIAGRALAQLNVTLKKTRKEVEKYIGR-----GTGfvaSEIPFTPRAKRV 87
Cdd:PRK10865 14 LADAQSLALGHDnqFIEPLHLMSALLNQEGGSVRPLLTSAGINAGQLRTDINQALSRlpqveGTG---GDVQPSQDLVRV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 88 LEMSIHEAQDLGVNYVGTEHILLSLLnEADGIALRTLDRLRVNIPKLRHLIftyieEQQ---EDILKPPLSDQEKwllsr 164
Cdd:PRK10865 91 LNLCDKLAQKRGDNFISSELFVLAAL-ESRGTLADILKAAGATTANITQAI-----EQMrggESVNDQGAEDQRQ----- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 165 ekgnkwttsTLENYSENITQEALDKRLDPVIGRNEEINALVKVLGRRRKNNPVLVGEAGVGKTACAEGLALLMVSGECPE 244
Cdd:PRK10865 160 ---------ALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPE 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 245 FLDNHAVLCLDLGSVLAGTKYRGEFEERMKTIIEDVQKN-GKIILVIDEIHTIVGAGAAEGAVDAANLLKPALARGTLRL 323
Cdd:PRK10865 231 GLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQeGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHC 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 324 IGATTLDEYRKYIEKDPALERRFHSIVVEEPTVEVTIDILNGLRPEFQRHHALTYSSDSLTAAAQLASRFITDRNLPDKA 403
Cdd:PRK10865 311 VGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 404 IDVIDEAGSRVRLR--------NRLLPIGIQkLLIELHDTLKDIDEAVRT--------------------HDFNTAKLLL 455
Cdd:PRK10865 391 IDLIDEAASSIRMQidskpeelDRLDRRIIQ-LKLEQQALMKESDEASKKrldmlneelsdkerqyseleEEWKAEKASL 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 456 DHEVEVRTHLRIMKYAL-----------------------------ASKDEYRKKMVTFDRVLEQDVTEVVSAWTGVPVT 506
Cdd:PRK10865 470 SGTQTIKAELEQAKIAIeqarrvgdlarmselqygkipelekqlaaATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVS 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 507 KINESENERLKKMEDILHERLIGQHHAIVAVSKAVRRARVGIQDPKRPIASFIFAGPTGVGKTELTKALAEYIFDTEKNM 586
Cdd:PRK10865 550 RMLESEREKLLRMEQELHHRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAM 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 587 IRFDMSEFMERHTVAKLIGSPPGYVGHEDGGQLTDAVRRKPYSIVLFDEVEKAHPDVFNLFLQILDDGHLSDSKGRLISF 666
Cdd:PRK10865 630 VRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDF 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 667 KNCIIVMTTNLGARVIErespilpkSKMGfNRRYEETKEqresrkievmvntdgtfllkppvkkevnaddekkfatisaL 746
Cdd:PRK10865 710 RNTVVIMTSNLGSDLIQ--------ERFG-ELDYAHMKE----------------------------------------L 740
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 747 VQEELKKFFRPEFLNRIDDIIVFNHLSKHDIWEICGILLKGLGKRLGEQGATLSVDNAVQYYLTEEGYDPVYGARPLRRA 826
Cdd:PRK10865 741 VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHISDEALKLLSENGYDPVYGARPLKRA 820
|
890 900
....*....|....*....|....
gi 118411220 827 ITKLLEDRLAMACLDNPIQPGTHI 850
Cdd:PRK10865 821 IQQQIENPLAQQILSGELVPGKVI 844
|
|
| VI_ClpV1 |
TIGR03345 |
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, ... |
22-841 |
0e+00 |
|
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274528 [Multi-domain] Cd Length: 852 Bit Score: 611.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 22 RMGHNFVGTEQVLLGILGQRHGIAGRALAQLNVTLKKTRKEVEKYIGRG-TGfvASEIP-FTPRAKRVLEMSIHEAQ-DL 98
Cdd:TIGR03345 18 ARGHPEVELEHWLLALLDQPDSDLAAILRHFGVDLGRLKADLARALDKLpRG--NTRTPvFSPHLVELLQEAWLLASlEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 99 GVNYVGTEHILLSLLNEADgiaLRTLDR------LRVNIPKLRHLIFTYIEEQQEDILKPPLSDQekwLLSREKGNKwtT 172
Cdd:TIGR03345 96 GDGRIRSGHLLLALLTDPE---LRRLLGsispelAKIDREALREALPALVEGSAEASAAAADAAP---AGAAAGAAG--T 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 173 STLENYSENITQEALDKRLDPVIGRNEEINALVKVLGRRRKNNPVLVGEAGVGKTACAEGLALLMVSGECPEFLDNHAVL 252
Cdd:TIGR03345 168 SALDQYTTDLTAQAREGKIDPVLGRDDEIRQMIDILLRRRQNNPILTGEAGVGKTAVVEGLALRIAAGDVPPALRNVRLL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 253 CLDLGSVLAGTKYRGEFEERMKTIIEDVQKNGK-IILVIDEIHTIVGAGAAEGAVDAANLLKPALARGTLRLIGATTLDE 331
Cdd:TIGR03345 248 SLDLGLLQAGASVKGEFENRLKSVIDEVKASPQpIILFIDEAHTLIGAGGQAGQGDAANLLKPALARGELRTIAATTWAE 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 332 YRKYIEKDPALERRFHSIVVEEPTVEVTIDILNGLRPEFQRHHALTYSSDSLTAAAQLASRFITDRNLPDKAIDVIDEAG 411
Cdd:TIGR03345 328 YKKYFEKDPALTRRFQVVKVEEPDEETAIRMLRGLAPVLEKHHGVLILDEAVVAAVELSHRYIPGRQLPDKAVSLLDTAC 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 412 SRVRLRNRLLPIGIQKLLIELHDTLKDIDEAVRTHDFN----------TAKLLLDHE---------------VEVRTHLR 466
Cdd:TIGR03345 408 ARVALSQNATPAALEDLRRRIAALELELDALEREAALGadhderlaelRAELAALEAelaalearwqqekelVEAILALR 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 467 IMKYALASKDE-----YRKKMVT---------------FDRVLEQDVTEVVSAWTGVPVTKINESENERLKKMEDILHER 526
Cdd:TIGR03345 488 AELEADADAPAddddaLRAQLAEleaalasaqgeeplvFPEVDAQAVAEVVADWTGIPVGRMVRDEIEAVLSLPDRLAER 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 527 LIGQHHAIVAVSKAVRRARVGIQDPKRPIASFIFAGPTGVGKTELTKALAEYIFDTEKNMIRFDMSEFMERHTVAKLIGS 606
Cdd:TIGR03345 568 VIGQDHALEAIAERIRTARAGLEDPRKPLGVFLLVGPSGVGKTETALALAELLYGGEQNLITINMSEFQEAHTVSRLKGS 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 607 PPGYVGHEDGGQLTDAVRRKPYSIVLFDEVEKAHPDVFNLFLQILDDGHLSDSKGRLISFKNCIIVMTTNLGARVIERES 686
Cdd:TIGR03345 648 PPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFYQVFDKGVMEDGEGREIDFKNTVILLTSNAGSDLIMALC 727
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 687 pilpkskmgfnrryeetkeqresrkievmvnTDGTFLLKPpvkkevnaddekkfATISALVQEELKKFFRPEFLNRIdDI 766
Cdd:TIGR03345 728 -------------------------------ADPETAPDP--------------EALLEALRPELLKVFKPAFLGRM-TV 761
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118411220 767 IVFNHLSKHDIWEICGILLKGLGKRLGEQ-GATLSVDNAVQYYLTEEGYDPVYGARPLRRAITKLLEDRLAMACLD 841
Cdd:TIGR03345 762 IPYLPLDDDVLAAIVRLKLDRIARRLKENhGAELVYSEALVEHIVARCTEVESGARNIDAILNQTLLPELSRQILE 837
|
|
| clpA |
PRK11034 |
ATP-dependent Clp protease ATP-binding subunit; Provisional |
14-836 |
0e+00 |
|
ATP-dependent Clp protease ATP-binding subunit; Provisional
Pssm-ID: 236828 [Multi-domain] Cd Length: 758 Bit Score: 557.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 14 MLAQE----------ESRRMGHNFVGTEQVLLGILGqrHGIAGRALAQLNVTLKKTRKEVEKYIGRGTGFV-----ASEI 78
Cdd:PRK11034 1 MLNQElelslnmafaRAREHRHEFMTVEHLLLALLS--NPSAREALEACSVDLVALRQELEAFIEQTTPVLpaseeERDT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 79 PFTPRAKRVLEMSIHEAQDLGVNYVGTEHILLSLLNEADGIA---LRTLDRLRVNIPK-LRHLIFTYIEEQQEDILKPPL 154
Cdd:PRK11034 79 QPTLSFQRVLQRAVFHVQSSGRSEVTGANVLVAIFSEQESQAaylLRKHEVSRLDVVNfISHGTRKDEPSQSSDPGSQPN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 155 SDQEkwLLSREKgnkwttstLENYSENITQEALDKRLDPVIGRNEEINALVKVLGRRRKNNPVLVGEAGVGKTACAEGLA 234
Cdd:PRK11034 159 SEEQ--AGGEER--------MENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLA 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 235 LLMVSGECPEFLDNHAVLCLDLGSVLAGTKYRGEFEERMKTIIEDVQKNGKIILVIDEIHTIVGAGAAEGA-VDAANLLK 313
Cdd:PRK11034 229 WRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGqVDAANLIK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 314 PALARGTLRLIGATTLDEYRKYIEKDPALERRFHSIVVEEPTVEVTIDILNGLRPEFQRHHALTYSSDSLTAAAQLASRF 393
Cdd:PRK11034 309 PLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKY 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 394 ITDRNLPDKAIDVIDEAGSrvrlRNRLLPigiqkllielhdtlkdideavrthdfntakllldhevevrthlrimkyalA 473
Cdd:PRK11034 389 INDRHLPDKAIDVIDEAGA----RARLMP--------------------------------------------------V 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 474 SKdeyRKKMVTFdrvleQDVTEVVSAWTGVPVTKINESENERLKKMEDILHERLIGQHHAIVAVSKAVRRARVGIQDPKR 553
Cdd:PRK11034 415 SK---RKKTVNV-----ADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMSRAGLGHEHK 486
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 554 PIASFIFAGPTGVGKTELTKALAEyIFDTEknMIRFDMSEFMERHTVAKLIGSPPGYVGHEDGGQLTDAVRRKPYSIVLF 633
Cdd:PRK11034 487 PVGSFLFAGPTGVGKTEVTVQLSK-ALGIE--LLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLL 563
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 634 DEVEKAHPDVFNLFLQILDDGHLSDSKGRLISFKNCIIVMTTNLGARVIERESpilpkskMGFnrryeetKEQRESrkie 713
Cdd:PRK11034 564 DEIEKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKS-------IGL-------IHQDNS---- 625
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 714 vmvnTDGtfllkppvkkevnaddekkfatisalvQEELKKFFRPEFLNRIDDIIVFNHLSKHDIWEICGILLKGLGKRLG 793
Cdd:PRK11034 626 ----TDA---------------------------MEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQAQLD 674
|
810 820 830 840
....*....|....*....|....*....|....*....|...
gi 118411220 794 EQGATLSVDNAVQYYLTEEGYDPVYGARPLRRAITKLLEDRLA 836
Cdd:PRK11034 675 QKGVSLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLA 717
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
515-769 |
1.11e-96 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 300.63 E-value: 1.11e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 515 RLKKMEDILHERLIGQHHAIVAVSKAVRRARVGIQDPKRPIASFIFAGPTGVGKTELTKALAEYIFDTEKNMIRFDMSEF 594
Cdd:cd19499 1 KLLNLEERLHERVVGQDEAVKAVSDAIRRARAGLSDPNRPIGSFLFLGPTGVGKTELAKALAELLFGDEDNLIRIDMSEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 595 MERHTVAKLIGSPPGYVGHEDGGQLTDAVRRKPYSIVLFDEVEKAHPDVFNLFLQILDDGHLSDSKGRLISFKNCIIVMT 674
Cdd:cd19499 81 MEKHSVSRLIGAPPGYVGYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGRLTDSHGRTVDFKNTIIIMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 675 TNlgarvierespilpkskmgfnrryeetkeqresrkievmvntdgtfllkppvkkevnaddekkfatisalvqeelkkF 754
Cdd:cd19499 161 SN-----------------------------------------------------------------------------H 163
|
250
....*....|....*
gi 118411220 755 FRPEFLNRIDDIIVF 769
Cdd:cd19499 164 FRPEFLNRIDEIVVF 178
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
553-766 |
7.21e-82 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 260.98 E-value: 7.21e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 553 RPIASFIFAGPTGVGKTELTKALAEYIFDTEKNMIRFDMSEFMERHTVAKLIGSPPGYVGHEDGGQLTDAVRRKPYSIVL 632
Cdd:pfam07724 1 RPIGSFLFLGPTGVGKTELAKALAELLFGDERALIRIDMSEYMEEHSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 633 FDEVEKAHPDVFNLFLQILDDGHLSDSKGRLISFKNCIIVMTTNLGARVIERESPIlpkskmGFNRRYEETKEQresrki 712
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLTDKQGRTVDFKNTLFIMTGNFGSEKISDASRL------GDSPDYELLKEE------ 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 118411220 713 evmvntdgtfllkppvkkevnaddekkfatisalVQEELKKFFRPEFLNRIDDI 766
Cdd:pfam07724 149 ----------------------------------VMDLLKKGFIPEFLGRLPII 168
|
|
| AAA_lid_9 |
pfam17871 |
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ... |
355-458 |
6.54e-32 |
|
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.
Pssm-ID: 465544 [Multi-domain] Cd Length: 104 Bit Score: 119.90 E-value: 6.54e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 355 TVEVTIDILNGLRPEFQRHHALTYSSDSLTAAAQLASRFITDRNLPDKAIDVIDEAGSRVRLRNRLLPIGIQKLLIELHD 434
Cdd:pfam17871 1 SVEEAIEILRGLKPKYEKHHGVRISDEALEAAVKLSKRYITDRFLPDKAIDLLDEACARVRLSQESKPEELEDLERELAK 80
|
90 100
....*....|....*....|....
gi 118411220 435 TLKDIDEAVRTHDFNTAKLLLDHE 458
Cdd:pfam17871 81 LEIEKEALEREQDFEKAERLAKLE 104
|
|
| ClpB_D2-small |
pfam10431 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
772-852 |
7.00e-24 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA, pfam00004) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerization, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilize the functional assembly. The domain is associated with two Clp_N, pfam02861, at the N-terminus as well as AAA, pfam00004 and AAA_2, pfam07724.
Pssm-ID: 463090 [Multi-domain] Cd Length: 81 Bit Score: 95.94 E-value: 7.00e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 772 LSKHDIWEICGILLKGLGKRLGEQGATLSVDNAVQYYLTEEGYDPVYGARPLRRAITKLLEDRLAMACLDNPIQPGTHIN 851
Cdd:pfam10431 1 LSKEELRKIVDLQLKELQKRLAERGITLELTDAAKDWLAEKGYDPEYGARPLRRAIQREIEDPLAEEILSGELKEGDTVR 80
|
.
gi 118411220 852 I 852
Cdd:pfam10431 81 V 81
|
|
| ClpB_D2-small |
smart01086 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
772-853 |
4.02e-18 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerisation, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilise the functional assembly. The domain is associated with two Clp_N at the N-terminus as well as AAA and AAA_2.
Pssm-ID: 198154 [Multi-domain] Cd Length: 90 Bit Score: 79.80 E-value: 4.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 772 LSKHDIWEICGILLKGLGKRLGEQGATLSVDNAVQYYLTEEGYDPVYGARPLRRAITKLLEDRLAMACLDNPIQPGTHIN 851
Cdd:smart01086 1 LDKEDLVRIVDLPLNALQKRLAEKGITLEFTDEALDWLAEKGYDPKYGARPLRRIIQRELEDPLAELILSGELKDGDTVV 80
|
..
gi 118411220 852 IT 853
Cdd:smart01086 81 VD 82
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
528-685 |
6.41e-18 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 81.42 E-value: 6.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 528 IGQHHAIVAVSKAVRRarvgiqdpkRPIASFIFAGPTGVGKTELTKALAEYIFDTEKNMIRFDMSEFMERHTVAKLIgsp 607
Cdd:cd00009 1 VGQEEAIEALREALEL---------PPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELF--- 68
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 118411220 608 pgyvGHEDGGQLTDAVRRKPYSIVLFDEVEKAHPDVFNLFLQILDDGHLSdskgrLISFKNCIIVMTTNLGARVIERE 685
Cdd:cd00009 69 ----GHFLVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDL-----RIDRENVRVIGATNRPLLGDLDR 137
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
195-354 |
1.21e-16 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 77.96 E-value: 1.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 195 IGRNEEINALVKVLGRRRKNNPVLVGEAGVGKTACAEGLALLMvsgecpeFLDNHAVLCLDLGSVLAGTKYRGEFEERMK 274
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANEL-------FRPGAPFLYLNASDLLEGLVVAELFGHFLV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 275 TI-IEDVQKNGKIILVIDEIHTIvGAGAAEGAVDAANLLKPALA-RGTLRLIGATTLDEYRKyieKDPALERRFHSIVVE 352
Cdd:cd00009 74 RLlFELAEKAKPGVLFIDEIDSL-SRGAQNALLRVLETLNDLRIdRENVRVIGATNRPLLGD---LDRALYDRLDIRIVI 149
|
..
gi 118411220 353 EP 354
Cdd:cd00009 150 PL 151
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
559-685 |
3.48e-13 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 67.78 E-value: 3.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 559 IFAGPTGVGKTELTKALAEYIFDTEKNMIRFDMSEFMERHTVAKLIGSPPGYVGHEDGGQ----LTDAVRRKPYSIVLFD 634
Cdd:smart00382 6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELrlrlALALARKLKPDVLILD 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 118411220 635 EVEKAHPDVFNLFLQILDDGHLsdsKGRLISFKNCIIVMTTNLGARVIERE 685
Cdd:smart00382 86 EITSLLDAEQEALLLLLEELRL---LLLLKSEKNLTVILTTNDEKDLGPAL 133
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
16-68 |
1.66e-12 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 62.54 E-value: 1.66e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 118411220 16 AQEESRRMGHNFVGTEQVLLGILGQRHGIAGRALAQLNVTLKKTRKEVEKYIG 68
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAIEKLLG 53
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
557-689 |
1.70e-12 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 65.39 E-value: 1.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 557 SFIFAGPTGVGKTELTKALAEYIFDTEKNMIRfdMSEFMERHTVAKLIGSPPGYVGHEDGGqLTDAVRRKpySIVLFDEV 636
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQ--LTRDTTEEDLFGRRNIDPGGASWVDGP-LVRAAREG--EIAVLDEI 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 118411220 637 EKAHPDVFNLFLQILDDGHLS-DSKGRLISFKNC--IIVMTTNLGARVIERESPIL 689
Cdd:pfam07728 76 NRANPDVLNSLLSLLDERRLLlPDGGELVKAAPDgfRLIATMNPLDRGLNELSPAL 131
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
537-683 |
1.74e-11 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 63.07 E-value: 1.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 537 VSKAVRRARVGIQDPKRPIASFIFAGPTGVGKTELTKALAEyifDTEKNMIRFDMSEFMERHtvakligsppGYVGHEDG 616
Cdd:cd19481 8 AVEAPRRGSRLRRYGLGLPKGILLYGPPGTGKTLLAKALAG---ELGLPLIVVKLSSLLSKY----------VGESEKNL 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 118411220 617 GQLTDAVRRKPYSIVLFDEVEKAHPD------------VFNLFLQILDDghlsdskgrLISFKNCIIVMTTNLGARVIE 683
Cdd:cd19481 75 RKIFERARRLAPCILFIDEIDAIGRKrdssgesgelrrVLNQLLTELDG---------VNSRSKVLVIAATNRPDLLDP 144
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
218-346 |
1.92e-11 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 62.23 E-value: 1.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 218 LVGEAGVGKTACAEGLA------LLMVSGecPEFLDnhavlcldlgsvlagtKYRGEFEERMKTIIEDVQKNGKIILVID 291
Cdd:pfam00004 3 LYGPPGTGKTTLAKAVAkelgapFIEISG--SELVS----------------KYVGESEKRLRELFEAAKKLAPCVIFID 64
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118411220 292 EIHTIVGAGAAEG---AVDAANLLKPALARGTLR-----LIGATTldeyrkYIEK-DPALERRF 346
Cdd:pfam00004 65 EIDALAGSRGSGGdseSRRVVNQLLTELDGFTSSnskviVIAATN------RPDKlDPALLGRF 122
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
94-138 |
3.27e-08 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 50.60 E-value: 3.27e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 118411220 94 EAQDLGVNYVGTEHILLSLLNEADGIALRTLDRLRVNIPKLRHLI 138
Cdd:pfam02861 4 LARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAI 48
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
212-354 |
7.97e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 52.38 E-value: 7.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 212 RKNNPVLVGEAGVGKTACAEGLALLMVSGECPEFLDN-----HAVLCLDLGSVLAGTKYRGEFEERMKTIIEDVQKNGKI 286
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDgedilEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 287 ILVIDEIHTIVGAG--AAEGAVDAANLLKPALARGTLRLIGATTLDEyrkyIEKDPALERRFHSIVVEEP 354
Cdd:smart00382 81 VLILDEITSLLDAEqeALLLLLEELRLLLLLKSEKNLTVILTTNDEK----DLGPALLRRRFDRRIVLLL 146
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
74-363 |
3.61e-06 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 50.29 E-value: 3.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 74 VASEIPFTPRAKRVLEMSIHEAQDLGVNYVGTEHILLSLLNEADGIALRTLDRLRVNIPKLRHLIFTYIEEQQEDILKPP 153
Cdd:COG0464 45 LLLLLALLLVELLLLLLSGALAALLLLALLLLALLALLAALLSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRE 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 154 LSDQEKWLLSRekgnkwTTSTLENYSENITQEALDKRLDPVIGRNE------EINALVKVLGRRRKNNPV-------LVG 220
Cdd:COG0464 125 SAEALALAAPL------VTYEDIGGLEEELLELREAILDDLGGLEEvkeelrELVALPLKRPELREEYGLppprgllLYG 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 221 EAGVGKTACAEGLAllmvsGECpefldNHAVLCLDLGSVLAgtKYRGEFEERMKTIIEDVQKNGKIILVIDEIHTIVGAG 300
Cdd:COG0464 199 PPGTGKTLLARALA-----GEL-----GLPLIEVDLSDLVS--KYVGETEKNLREVFDKARGLAPCVLFIDEADALAGKR 266
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118411220 301 AAEGAVDA----ANLLK--PALARGTLrLIGATtldeYRkyIEK-DPALERRFHSIV-VEEPTVEVTIDIL 363
Cdd:COG0464 267 GEVGDGVGrrvvNTLLTemEELRSDVV-VIAAT----NR--PDLlDPALLRRFDEIIfFPLPDAEERLEIF 330
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
374-677 |
2.31e-05 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 47.60 E-value: 2.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 374 HALTYSSDSLTAAAQLASRFITDRNLPDKAIDVIDEAGSRVRLRNRLLPIGIQKLLIELHDTLKDIDEAVRTHDFNTAKL 453
Cdd:COG0464 6 ALAVALALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLALLAAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 454 LLDHEVEVRTHLRIMKYALASKDEYRKKMVTFDRVLEQDVTEVVSAWTGVPVTKINESENERLKKMEDILHERLIGQHHA 533
Cdd:COG0464 86 LSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLEEELLELREAILDDLGGLEEV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 534 IVAVSKAVRRARVGIQDPKR----PIASFIFAGPTGVGKTELTKALAEYIfdtEKNMIRFDMSEFmerhtVAKLIGSPPG 609
Cdd:COG0464 166 KEELRELVALPLKRPELREEyglpPPRGLLLYGPPGTGKTLLARALAGEL---GLPLIEVDLSDL-----VSKYVGETEK 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 118411220 610 YVghedgGQLTDAVRRKPYSIVLFDEVEKAHPD-----------VFNLFLQILDDGHlsdskgrlisfKNCIIVMTTNL 677
Cdd:COG0464 238 NL-----REVFDKARGLAPCVLFIDEADALAGKrgevgdgvgrrVVNTLLTEMEELR-----------SDVVVIAATNR 300
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
559-676 |
2.45e-05 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 44.89 E-value: 2.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 559 IFAGPTGVGKTELTKALAEYIFdteKNMIRFDMSEFMErhtvaKLIGSPPGYVghedgGQLTDAVRRKPYSIVLFDEVEK 638
Cdd:pfam00004 2 LLYGPPGTGKTTLAKAVAKELG---APFIEISGSELVS-----KYVGESEKRL-----RELFEAAKKLAPCVIFIDEIDA 68
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 118411220 639 AHP-----------DVFNLFLQILDdghlsdskGRLISFKNCIIVMTTN 676
Cdd:pfam00004 69 LAGsrgsggdsesrRVVNQLLTELD--------GFTSSNSKVIVIAATN 109
|
|
| Zeta_toxin |
pfam06414 |
Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is ... |
550-651 |
2.86e-05 |
|
Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid.
Pssm-ID: 428926 Cd Length: 192 Bit Score: 45.82 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 550 DPKRPIASFIfAGPTGVGKTELTKALAEYiFDTEKNMIRFDMSEFMERH-TVAKLIGSPP---GYVGHEDGGQLT----D 621
Cdd:pfam06414 7 SQERPKAILL-GGQPGAGKTELARALLDE-LGRQGNVVRIDPDDFRELHpHYRELQAADPktaSEYTQPDASRWVekllQ 84
|
90 100 110
....*....|....*....|....*....|
gi 118411220 622 AVRRKPYSIVLfdEVEKAHPDVFNLFLQIL 651
Cdd:pfam06414 85 HAIENGYNIIL--EGTLRSPDVAKKIARAL 112
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
218-350 |
3.78e-05 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 44.97 E-value: 3.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 218 LVGEAGVGKTACAEGLAllmvsgecpefldNHAVLCL---DLGSVLagTKYRGEFEERMKTIIEDVQKNGKIILVIDEIH 294
Cdd:cd19481 31 LYGPPGTGKTLLAKALA-------------GELGLPLivvKLSSLL--SKYVGESEKNLRKIFERARRLAPCILFIDEID 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118411220 295 TIVGAGAAEGAVDAANLLKPAL--------ARGTLRLIGATTLDEyrkyiEKDPALER--RFHSIV 350
Cdd:cd19481 96 AIGRKRDSSGESGELRRVLNQLlteldgvnSRSKVLVIAATNRPD-----LLDPALLRpgRFDEVI 156
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
187-322 |
1.94e-04 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 42.93 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 187 LDKRL-DPVIGRNEEINALVKVL-----GRRRKNNP----VLVGEAGVGKTACAEGLALLMvsgecpeFLDNHAVLCLDL 256
Cdd:cd19499 5 LEERLhERVVGQDEAVKAVSDAIrraraGLSDPNRPigsfLFLGPTGVGKTELAKALAELL-------FGDEDNLIRIDM 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 118411220 257 G--------SVLAGT--KYRGeFEERmKTIIEDVQKNGKIILVIDEIhtivgagaaEGA-VDAANLLKPALARGTLR 322
Cdd:cd19499 78 SeymekhsvSRLIGAppGYVG-YTEG-GQLTEAVRRKPYSVVLLDEI---------EKAhPDVQNLLLQVLDDGRLT 143
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
204-363 |
2.21e-04 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 44.90 E-value: 2.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 204 LVKVLGRRRKNNPVLVGEAGVGKTACAEGLA------LLMVSGecPEFLdnhavlcldlgsvlagTKYRGEFEERMKTII 277
Cdd:TIGR01243 203 LFEHLGIEPPKGVLLYGPPGTGKTLLAKAVAneagayFISING--PEIM----------------SKYYGESEERLREIF 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 278 EDVQKNGKIILVIDEIHTIV-----GAGAAEGAVDAA--NLLKPALARGTLRLIGATTLDEyrkyiEKDPALER--RF-H 347
Cdd:TIGR01243 265 KEAEENAPSIIFIDEIDAIApkreeVTGEVEKRVVAQllTLMDGLKGRGRVIVIGATNRPD-----ALDPALRRpgRFdR 339
|
170
....*....|....*.
gi 118411220 348 SIVVEEPTVEVTIDIL 363
Cdd:TIGR01243 340 EIVIRVPDKRARKEIL 355
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
562-655 |
2.25e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 41.94 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 562 GPTGVGKTELTKALAEYIFDTEKNMIRFDMSEFME----RHTVAKLIGSPPGYVG--HEDGGQLTDAV-RRKPYSIVLFD 634
Cdd:pfam13401 12 GESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSpkdlLRALLRALGLPLSGRLskEELLAALQQLLlALAVAVVLIID 91
|
90 100
....*....|....*....|.
gi 118411220 635 EVEKAHPDVFNLFLQILDDGH 655
Cdd:pfam13401 92 EAQHLSLEALEELRDLLNLSS 112
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
215-345 |
1.10e-03 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 42.73 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 215 NPVLVGEAGVGKTACAEGLALLMVSgecpEFLDnhavlcldLGSVLAGTKyrgEFEERMKTIIEDVQKNGK-IILVIDEI 293
Cdd:PRK13341 54 SLILYGPPGVGKTTLARIIANHTRA----HFSS--------LNAVLAGVK---DLRAEVDRAKERLERHGKrTILFIDEV 118
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 118411220 294 HTIVGAGAaegavDAanlLKPALARGTLRLIGATTLDeyrKYIEKDPALERR 345
Cdd:PRK13341 119 HRFNKAQQ-----DA---LLPWVENGTITLIGATTEN---PYFEVNKALVSR 159
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
514-589 |
1.97e-03 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 41.61 E-value: 1.97e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 118411220 514 ERL--KKMEDIlherlIGQHHaIVAVSKAVRRArvgIQdpKRPIASFIFAGPTGVGKTELTKALAEYifdTEKNMIRF 589
Cdd:PRK13342 4 ERMrpKTLDEV-----VGQEH-LLGPGKPLRRM---IE--AGRLSSMILWGPPGTGKTTLARIIAGA---TDAPFEAL 67
|
|
| RecA-like_HslU |
cd19498 |
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease ... |
523-638 |
2.79e-03 |
|
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease HslVU. In HslVU, HslU ATPase serves to unfold and translocate protein substrate, and the HslV protease degrades the unfolded proteins. This RecA-like_HslU subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410906 [Multi-domain] Cd Length: 183 Bit Score: 39.67 E-value: 2.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 523 LHERLIGQHHAIVAVSKAVR----RARV--GIQDPKRPiASFIFAGPTGVGKTELTKALAEYIfdtEKNMIRFDMSEFME 596
Cdd:cd19498 9 LDKYIIGQDEAKRAVAIALRnrwrRMQLpeELRDEVTP-KNILMIGPTGVGKTEIARRLAKLA---GAPFIKVEATKFTE 84
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 118411220 597 rhtvakligspPGYVGHEDGGQLTDAVRrkpySIVLFDEVEK 638
Cdd:cd19498 85 -----------VGYVGRDVESIIRDLVE----GIVFIDEIDK 111
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
525-580 |
2.90e-03 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 40.95 E-value: 2.90e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 118411220 525 ERLIGQHHAIVAVSKAVRRARVGiqdpkrpiASFIFAGPTGVGKTELTKALAEYIF 580
Cdd:COG2812 10 DDVVGQEHVVRTLKNALASGRLA--------HAYLFTGPRGVGKTTLARILAKALN 57
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
544-637 |
4.05e-03 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 40.37 E-value: 4.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 544 ARVGIQDPKRpiasFIFAGPTGVGKTELTKALAEYifdTEKNMIRFDMSEFMERhtvakligsppgYVGheDGGQLTDAV 623
Cdd:COG1222 105 RKYGIEPPKG----VLLYGPPGTGKTLLAKAVAGE---LGAPFIRVRGSELVSK------------YIG--EGARNVREV 163
|
90
....*....|....*...
gi 118411220 624 ----RRKPYSIVLFDEVE 637
Cdd:COG1222 164 felaREKAPSIIFIDEID 181
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
218-346 |
4.78e-03 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 38.81 E-value: 4.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 218 LVGEAGVGKTACAEGLA------LLMVSGecPEFLdnhavlcldlgsvlagTKYRGEFEERMKTIIEDVQKNGKIILVID 291
Cdd:cd19503 39 LHGPPGTGKTLLARAVAneaganFLSISG--PSIV----------------SKYLGESEKNLREIFEEARSHAPSIIFID 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118411220 292 EIHTIVGA-GAAEGAVDAA------NLLKPALARGTLRLIGATTLDEyrkyiEKDPALER--RF 346
Cdd:cd19503 101 EIDALAPKrEEDQREVERRvvaqllTLMDGMSSRGKVVVIAATNRPD-----AIDPALRRpgRF 159
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
557-653 |
5.69e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 39.86 E-value: 5.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 557 SFIFAGPTGVGKTELTKALAEYI----FDTEKNMIRFDMSEFmerhtvakligSPPGYVGHEDGGQLTDAVRRKP----Y 628
Cdd:PRK14970 41 ALLFCGPRGVGKTTCARILARKInqpgYDDPNEDFSFNIFEL-----------DAASNNSVDDIRNLIDQVRIPPqtgkY 109
|
90 100
....*....|....*....|....*
gi 118411220 629 SIVLFDEVEKAHPDVFNLFLQILDD 653
Cdd:PRK14970 110 KIYIIDEVHMLSSAAFNAFLKTLEE 134
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
193-312 |
6.88e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 38.25 E-value: 6.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118411220 193 PVIGRNEEINALVKVLGRRRKNNP---VLVGEAGVGKTACAEGLALLmVSGECPEFLDNHAVLCLDLGSVLAGTKYRGEF 269
Cdd:pfam13191 1 RLVGREEELEQLLDALDRVRSGRPpsvLLTGEAGTGKTTLLRELLRA-LERDGGYFLRGKCDENLPYSPLLEALTREGLL 79
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 118411220 270 EErmktiIEDVQKNGKIILVIDEIHTIVGAGAAEGAVDAANLL 312
Cdd:pfam13191 80 RQ-----LLDELESSLLEAWRAALLEALAPVPELPGDLAERLL 117
|
|
| |
