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Conserved domains on  [gi|1181491227|ref|YP_009353131|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Campephilus imperialis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 7.75e-53

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 165.69  E-value: 7.75e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227   1 MTYFMLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  81 TWGDWRVLGYGVGLIGVLVVGVVVGGVEQG-LKLGVWTVDGGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGLLLTLFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGmEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1181491227 160 ELVRGLSCGAIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 7.75e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 165.69  E-value: 7.75e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227   1 MTYFMLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  81 TWGDWRVLGYGVGLIGVLVVGVVVGGVEQG-LKLGVWTVDGGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGLLLTLFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGmEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1181491227 160 ELVRGLSCGAIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 1.51e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.97  E-value: 1.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  17 LAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVAL-AADPFPETWGDWRVLGYGVGLI 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1181491227  96 GVLVVGVVVGgveqGLKLGVWTVDGGGAVSVRLDFSGVAMFYSWGVgVFLVAGWGLLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVL----LSASLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 7.75e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 165.69  E-value: 7.75e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227   1 MTYFMLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  81 TWGDWRVLGYGVGLIGVLVVGVVVGGVEQG-LKLGVWTVDGGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGLLLTLFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGmEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1181491227 160 ELVRGLSCGAIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 7.71e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 160.69  E-value: 7.71e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227   1 MTYFMLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  81 TWGDWRVLGYGVGLIGVLVVGVVVGGVEQGLKLGVWTVDGGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGLLLTLFVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1181491227 161 LVRGLSCGAIRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 2.55e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 151.92  E-value: 2.55e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227   1 MTYFMLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  81 TWGDWRVLGYGVGLIGVLVVGVVVGGVEQGLKlGVWTVDGGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGLLLTLFVVLE 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLE-FLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                         170
                  ....*....|...
gi 1181491227 161 LVRGLSCGAIRAV 173
Cdd:MTH00065  160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 1.18e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 104.11  E-value: 1.18e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227   1 MTYFMLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  81 TWGD-WRVLGYGVGLIGVLVVGVVVGGVEQGLKLGV-------WTV-DGGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGL 151
Cdd:MTH00109   82 TWVSnKVVLGALLLGLLMELLLVLYVLKDDEVEVVFnfnglgdWVIyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 1181491227 152 LLTLFVVLELVRG 164
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 7.82e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 91.59  E-value: 7.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227   1 MTYFMLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  81 TWGDWRVLGYGVGLIGVLVVGVVVGGVEQGLKLGVwtvdgGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGLLLTLFVVLE 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWM-----GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 1181491227 161 LVRGLSCGAIRAV 173
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 10-172 1.40e-15

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 69.93  E-value: 1.40e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  10 VCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPETWGDWRVLG 89
Cdd:MTH00045    8 ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVLV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  90 YGVGLIGVLVVGvvvggveqgLKLGVWTVDGGGAVSVRLDFSGVAMFYSWGVGVFLVAGWGLLLTLFVVLELVRGLSCGA 169
Cdd:MTH00045   88 LSLLLSLWVFIS---------FDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSS 158


                  ...
gi 1181491227 170 IRA 172
Cdd:MTH00045  159 LRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 1.51e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.97  E-value: 1.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181491227  17 LAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVAL-AADPFPETWGDWRVLGYGVGLI 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1181491227  96 GVLVVGVVVGgveqGLKLGVWTVDGGGAVSVRLDFSGVAMFYSWGVgVFLVAGWGLLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVL----LSASLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 2.39e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 39.71  E-value: 2.39e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1181491227   7 FLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVALVLFMVYLGGMLVVFVYSVAL 73
Cdd:MTH00021    1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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