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Conserved domains on  [gi|1178431667|ref|NP_001337248|]
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outer dynein arm-docking complex subunit 4 isoform 2 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
292-471 7.83e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 7.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 292 GSLQKAEKVLKKVLEWNKEEVpnkdelvgNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRVFA 371
Cdd:COG0457    56 GRYEEALADYEQALELDPDDA--------EALNNLGLALQALGRYEEALEDYDKALELDPDD------AEALYNLGLALL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 372 RVGKFQQAIDTWEEKIPLAKTTLEktwLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQGLGR 451
Cdd:COG0457   122 ELGRYDEAIEAYERALELDPDDAD---ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLA 198

                         170       180
                  ....*....|....*....|
gi 1178431667 452 CQQGYHQRTEENQLRGESQR 471
Cdd:COG0457   199 LLLALEQALRKKLAILTLAA 218
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-113 6.49e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.39  E-value: 6.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  15 SYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTM 94
Cdd:COG0457    44 ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123

                          90
                  ....*....|....*....
gi 1178431667  95 GDFEFALVFYHRGYKLRPD 113
Cdd:COG0457   124 GRYDEAIEAYERALELDPD 142
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
292-471 7.83e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 7.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 292 GSLQKAEKVLKKVLEWNKEEVpnkdelvgNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRVFA 371
Cdd:COG0457    56 GRYEEALADYEQALELDPDDA--------EALNNLGLALQALGRYEEALEDYDKALELDPDD------AEALYNLGLALL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 372 RVGKFQQAIDTWEEKIPLAKTTLEktwLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQGLGR 451
Cdd:COG0457   122 ELGRYDEAIEAYERALELDPDDAD---ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLA 198

                         170       180
                  ....*....|....*....|
gi 1178431667 452 CQQGYHQRTEENQLRGESQR 471
Cdd:COG0457   199 LLLALEQALRKKLAILTLAA 218
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-113 6.49e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.39  E-value: 6.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  15 SYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTM 94
Cdd:COG0457    44 ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123

                          90
                  ....*....|....*....
gi 1178431667  95 GDFEFALVFYHRGYKLRPD 113
Cdd:COG0457   124 GRYDEAIEAYERALELDPD 142
TPR_12 pfam13424
Tetratricopeptide repeat;
318-391 5.24e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 5.24e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1178431667 318 LVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPD--AKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAK 391
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDhpLTATTLLNLGRLYLELGRYEEALELLERALALAE 76
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
292-471 7.83e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 7.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 292 GSLQKAEKVLKKVLEWNKEEVpnkdelvgNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRVFA 371
Cdd:COG0457    56 GRYEEALADYEQALELDPDDA--------EALNNLGLALQALGRYEEALEDYDKALELDPDD------AEALYNLGLALL 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 372 RVGKFQQAIDTWEEKIPLAKTTLEktwLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQGLGR 451
Cdd:COG0457   122 ELGRYDEAIEAYERALELDPDDAD---ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLA 198

                         170       180
                  ....*....|....*....|
gi 1178431667 452 CQQGYHQRTEENQLRGESQR 471
Cdd:COG0457   199 LLLALEQALRKKLAILTLAA 218
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 290-449 5.18e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 5.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 290 AEGSLQKAEKVLKKVLEWNKEEVPNKDELvgnlysciGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRV 369
Cdd:COG2956   122 QEGDWEKAIEVLERLLKLGPENAHAYCEL--------AELYLEQGDYDEAIEALEKALKLDPDC------ARALLLLAEL 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 370 FARVGKFQQAIDTWEEKIPLAKTTLEktwLFHEIGRCYLELDQAWQAQNYgekSQQCAEEEGDIEWQLNASVLVAQAQGL 449
Cdd:COG2956   188 YLEQGDYEEAIAALERALEQDPDYLP---ALPRLAELYEKLGDPEEALEL---LRKALELDPSDDLLLALADLLERKEGL 261
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-113 6.49e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.39  E-value: 6.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  15 SYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTM 94
Cdd:COG0457    44 ALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL 123

                          90
                  ....*....|....*....
gi 1178431667  95 GDFEFALVFYHRGYKLRPD 113
Cdd:COG0457   124 GRYDEAIEAYERALELDPD 142
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 230-423 4.91e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.22  E-value: 4.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 230 NYLDTHSNFWRQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVLEWNk 309
Cdd:COG3914    30 AELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALN- 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 310 eevPNKDELVGNLysciGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRVFARVGKFQQAIDTWEEKIPL 389
Cdd:COG3914   109 ---PDNAEALFNL----GNLLLALGRLEEALAALRRALALNPDF------AEAYLNLGEALRRLGRLEEAIAALRRALEL 175

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1178431667 390 AKTTLEktwLFHEIGRCYLELDQAWQAQNYGEKS 423
Cdd:COG3914   176 DPDNAE---ALNNLGNALQDLGRLEEAIAAYRRA 206
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 18-114 6.64e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.84  E-value: 6.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  18 AEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDF 97
Cdd:COG3914    83 LAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRL 162

                          90
                  ....*....|....*..
gi 1178431667  98 EFALVFYHRGYKLRPDR 114
Cdd:COG3914   163 EEAIAALRRALELDPDN 179
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-113 1.91e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.15  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  15 SYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTM 94
Cdd:COG0457    10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                          90
                  ....*....|....*....
gi 1178431667  95 GDFEFALVFYHRGYKLRPD 113
Cdd:COG0457    90 GRYEEALEDYDKALELDPD 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-126 2.19e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.77  E-value: 2.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  15 SYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTM 94
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1178431667  95 GDFEFALVFYHRGYKLRPDREFRVGIQKAQEA 126
Cdd:COG0457   158 GRYEEALELLEKLEAAALAALLAAALGEAALA 189
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 290-422 2.74e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 2.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 290 AEGSLQKAEKVLKKVLEWNKEEVPnkdelvgnLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRV 369
Cdd:COG4783    16 LAGDYDEAEALLEKALELDPDNPE--------AFALLGEILLQLGDLDEAIVLLHEALELDPDE------PEARLNLGLA 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1178431667 370 FARVGKFQQAIDTWEEKIPLAKTTLEktwLFHEIGRCYLELDQAWQAQNYGEK 422
Cdd:COG4783    82 LLKAGDYDEALALLEKALKLDPEHPE---AYLRLARAYRALGRPDEAIAALEK 131
TPR_12 pfam13424
Tetratricopeptide repeat;
318-391 5.24e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 5.24e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1178431667 318 LVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPD--AKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAK 391
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDhpLTATTLLNLGRLYLELGRYEEALELLERALALAE 76
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
289-423 6.41e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 6.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 289 SAEGSLQKAEKVLKKVLEwnkeevpnKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGR 368
Cdd:COG0457    19 RRLGRYEEAIEDYEKALE--------LDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEALNNLGL 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1178431667 369 VFARVGKFQQAIDTWEEKIPLAKttlEKTWLFHEIGRCYLELDQAWQAQNYGEKS 423
Cdd:COG0457    85 ALQALGRYEEALEDYDKALELDP---DDAEALYNLGLALLELGRYDEAIEAYERA 136
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
27-113 1.01e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  27 GEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKdAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHR 106
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                  ....*..
gi 1178431667 107 GYKLRPD 113
Cdd:COG3063    85 ALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 23-112 1.15e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  23 LYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALV 102
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                          90
                  ....*....|
gi 1178431667 103 FYHRGYKLRP 112
Cdd:COG5010   144 ALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 240-391 4.76e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.71  E-value: 4.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 240 RQQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLtsgSAEGSLQKAEKVLKKVLEWNkeevPNKDELV 319
Cdd:COG5010    19 KLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLY---NKLGDFEESLALLEQALQLD----PNNPELY 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1178431667 320 GNLysciGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRVFARVGKFQQAIDTWEEKIPLAK 391
Cdd:COG5010    92 YNL----ALLYSRSGDKDEAKEYYEKALALSPDN------PNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 290-422 5.02e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.02  E-value: 5.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 290 AEGSLQKAEKVLKKVLEWNKEEVPnkdelvgnLYSCIGNAQIELGQMEAALQSHRKDL-----------EIAKEY----- 353
Cdd:COG2956    20 LNGQPDKAIDLLEEALELDPETVE--------AHLALGNLYRRRGEYDRAIRIHQKLLerdpdraeallELAQDYlkagl 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 354 ------------DLPDAKSRALDNIGRVFARVGKFQQAIDTWEEkipLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYGE 421
Cdd:COG2956    92 ldraeellekllELDPDDAEALRLLAEIYEQEGDWEKAIEVLER---LLKLGPENAHAYCELAELYLEQGDYDEAIEALE 168


                  .
gi 1178431667 422 K 422
Cdd:COG2956   169 K 169
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
16-118 6.04e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.44  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  16 YMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTMG 95
Cdd:COG4785    76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                          90       100
                  ....*....|....*....|...
gi 1178431667  96 DFEFALVFYHRGYKLRPDREFRV 118
Cdd:COG4785   156 RYELAIADLEKALELDPNDPERA 178
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
289-449 7.81e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 7.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 289 SAEGSLQKAEKVLKKVLEWNkeevPNKDELVGNLysciGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGR 368
Cdd:COG0457    87 QALGRYEEALEDYDKALELD----PDDAEALYNL----GLALLELGRYDEAIEAYERALELDPDD------ADALYNLGI 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 369 VFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQG 448
Cdd:COG0457   153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232


                  .
gi 1178431667 449 L 449
Cdd:COG0457   233 L 233
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 16-129 1.11e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.40  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  16 YMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTMG 95
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1178431667  96 DFEFALVFYHRGYKLRPDR-EFRVGIQKAQEAINN 129
Cdd:COG4783    87 DYDEALALLEKALKLDPEHpEAYLRLARAYRALGR 121
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
323-422 1.15e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.76  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 323 YSCIGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRVFARVGKFQQAIDTWEEKIPLAkttLEKTWLFHE 402
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDD------AEALYNLGLAYLRLGRYEEALADYEQALELD---PDDAEALNN 81

                          90       100
                  ....*....|....*....|
gi 1178431667 403 IGRCYLELDQAWQAQNYGEK 422
Cdd:COG0457    82 LGLALQALGRYEEALEDYDK 101
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 27-123 1.45e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.83  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667  27 GEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHR 106
Cdd:COG4235    31 GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQK 110

                          90
                  ....*....|....*..
gi 1178431667 107 GYKLRPDREFRVGIQKA 123
Cdd:COG4235   111 LLALLPADAPARLLEAS 127
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 323-448 2.14e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.99  E-value: 2.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 323 YSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT----- 397
Cdd:pfam17874  43 TFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTLWALLQQGEILRAQGRLHQALETYQQALQLARDHGLQHlplhg 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1178431667 398 WLFHEIGRCYLELDQAWQAQNYGEKSQQCAeEEGDIEWQLNASVL---VAQAQG 448
Cdd:pfam17874 123 FLLVGLADLLYEWNDLEEAEQHAQQGIQLG-RQWEPDAAVDAYVLlarIALAQG 175
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 292-390 2.55e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.25  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431667 292 GSLQKAEKVLKKVLEWNKEEVpnkdelvgNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYdlpdakSRALDNIGRVFA 371
Cdd:COG4783    52 GDLDEAIVLLHEALELDPDEP--------EARLNLGLALLKAGDYDEALALLEKALKLDPEH------PEAYLRLARAYR 117

                          90
                  ....*....|....*....
gi 1178431667 372 RVGKFQQAIDTWEEKIPLA 390
Cdd:COG4783   118 ALGRPDEAIAALEKALELD 136
TPR_12 pfam13424
Tetratricopeptide repeat;
361-429 3.13e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.60  E-value: 3.13e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1178431667 361 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT-----WLFHEIGRCYLELDQAWQAQNYGEKSQQCAEE 429
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDhpltaTTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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