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Conserved domains on  [gi|1176771986|gb|OQY89862|]
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MAG: hypothetical protein B6D38_05560 [Anaerolineae bacterium UTCFX1]

Protein Classification

LamG domain-containing protein( domain architecture ID 366259)

LamG (Laminin G) domain-containing protein may serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LamG super family cl22861
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 37-204 3.33e-07

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


The actual alignment was detected with superfamily member pfam06439:

Pssm-ID: 473984  Cd Length: 182  Bit Score: 48.91  E-value: 3.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176771986  37 FNSSFNGSS-AGWSAVTGAWKltgSGYYRSNGIKDRMTSTKRVG------SYSNFAYSVRMKRVGAFANGVIIRGNPNsl 109
Cdd:pfam06439   2 WISLFNGKDlDGWKGAGGGGV---GGWKVEDGVLVDGSSGKGGGflitkkKFGDFELHLEFKITPGGNSGVFFRSQPE-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176771986 110 sFIKFWKSSYWFAYTNNGTFSIWKYPSkGAEVALKDWTASSAIVKNGWNTLKVTANGSNFKFYINGKLVAKVTDSSFRTG 189
Cdd:pfam06439  77 -EGQDFVKGYEVQILDSGGDLGLNRGT-GSLYGEIAPSANATFPPGEWNTYEIIVKGNRITVWLNGVLVVDFTDPDPETG 154

                         170
                  ....*....|....*
gi 1176771986 190 QVGigfyRDTPSGYL 204
Cdd:pfam06439 155 GGG----EPLKSGPI 165
 
Name Accession Description Interval E-value
3keto-disac_hyd pfam06439
3-keto-disaccharide hydrolase; This family has structural similarity to an endo-1,3-1,4-beta ...
 37-204 3.33e-07

3-keto-disaccharide hydrolase; This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. A member containing this domain, BT2157 from B. thetaiotaomicron, hydrolyses 3-ketotrehalose during trehalose degradation that proceeds through a 3-keto-glycoside intermediate. Other members containing this domain are involved in disaccharide catabolism with 3-ketoglycoside intermediates.


Pssm-ID: 399445  Cd Length: 182  Bit Score: 48.91  E-value: 3.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176771986  37 FNSSFNGSS-AGWSAVTGAWKltgSGYYRSNGIKDRMTSTKRVG------SYSNFAYSVRMKRVGAFANGVIIRGNPNsl 109
Cdd:pfam06439   2 WISLFNGKDlDGWKGAGGGGV---GGWKVEDGVLVDGSSGKGGGflitkkKFGDFELHLEFKITPGGNSGVFFRSQPE-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176771986 110 sFIKFWKSSYWFAYTNNGTFSIWKYPSkGAEVALKDWTASSAIVKNGWNTLKVTANGSNFKFYINGKLVAKVTDSSFRTG 189
Cdd:pfam06439  77 -EGQDFVKGYEVQILDSGGDLGLNRGT-GSLYGEIAPSANATFPPGEWNTYEIIVKGNRITVWLNGVLVVDFTDPDPETG 154

                         170
                  ....*....|....*
gi 1176771986 190 QVGigfyRDTPSGYL 204
Cdd:pfam06439 155 GGG----EPLKSGPI 165
 
Name Accession Description Interval E-value
3keto-disac_hyd pfam06439
3-keto-disaccharide hydrolase; This family has structural similarity to an endo-1,3-1,4-beta ...
 37-204 3.33e-07

3-keto-disaccharide hydrolase; This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. A member containing this domain, BT2157 from B. thetaiotaomicron, hydrolyses 3-ketotrehalose during trehalose degradation that proceeds through a 3-keto-glycoside intermediate. Other members containing this domain are involved in disaccharide catabolism with 3-ketoglycoside intermediates.


Pssm-ID: 399445  Cd Length: 182  Bit Score: 48.91  E-value: 3.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176771986  37 FNSSFNGSS-AGWSAVTGAWKltgSGYYRSNGIKDRMTSTKRVG------SYSNFAYSVRMKRVGAFANGVIIRGNPNsl 109
Cdd:pfam06439   2 WISLFNGKDlDGWKGAGGGGV---GGWKVEDGVLVDGSSGKGGGflitkkKFGDFELHLEFKITPGGNSGVFFRSQPE-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176771986 110 sFIKFWKSSYWFAYTNNGTFSIWKYPSkGAEVALKDWTASSAIVKNGWNTLKVTANGSNFKFYINGKLVAKVTDSSFRTG 189
Cdd:pfam06439  77 -EGQDFVKGYEVQILDSGGDLGLNRGT-GSLYGEIAPSANATFPPGEWNTYEIIVKGNRITVWLNGVLVVDFTDPDPETG 154

                         170
                  ....*....|....*
gi 1176771986 190 QVGigfyRDTPSGYL 204
Cdd:pfam06439 155 GGG----EPLKSGPI 165
Laminin_G_3 pfam13385
Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin ...
 82-185 9.00e-05

Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.


Pssm-ID: 463865 [Multi-domain]  Cd Length: 151  Bit Score: 41.60  E-value: 9.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176771986  82 SNFAYS--VRMKRVGAFANGVIIRGNPNSlsfikfwkssYWFAYTNNGTFSIWkypSKGAEVALKDWTASSAIVKNGWNT 159
Cdd:pfam13385  17 SDFTVSawVKPDSLPGWARAIISSSGGGG----------YSLGLDGDGRLRFA---VNGGNGGWDTVTSGASVPLGQWTH 83

                          90       100
                  ....*....|....*....|....*.
gi 1176771986 160 LKVTANGSNFKFYINGKLVAKVTDSS 185
Cdd:pfam13385  84 VAVTYDGGTLRLYVNGVLVGSSTLTG 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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