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Conserved domains on  [gi|1176253242|gb|OQY60698|]
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hypothetical protein B6245_00150 [Desulfobacteraceae bacterium 4572_88]

Protein Classification

class I SAM-dependent DNA methyltransferase( domain architecture ID 11471966)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:1904047
PubMed:  23180741|12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
14-138 1.55e-17

Predicted methyltransferase, contains TPR repeat [General function prediction only];


:

Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 77.35  E-value: 1.55e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  14 ADIYDD------WYQTCEPGLIRTLDDLA--QGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAKPGGDRip 85
Cdd:COG4976    15 ADSYDAalvedlGYEAPALLAEELLARLPpgPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYDR-- 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1176253242  86 VKIGNFADVDVQ-GSFSLIfIVFNTFYGLlsqDEQVLCFQNVANHLSENGVFLI 138
Cdd:COG4976    93 LLVADLADLAEPdGRFDLI-VAADVLTYL---GDLAAVFAGVARALKPGGLFIF 142
 
Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
14-138 1.55e-17

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 77.35  E-value: 1.55e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  14 ADIYDD------WYQTCEPGLIRTLDDLA--QGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAKPGGDRip 85
Cdd:COG4976    15 ADSYDAalvedlGYEAPALLAEELLARLPpgPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYDR-- 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1176253242  86 VKIGNFADVDVQ-GSFSLIfIVFNTFYGLlsqDEQVLCFQNVANHLSENGVFLI 138
Cdd:COG4976    93 LLVADLADLAEPdGRFDLI-VAADVLTYL---GDLAAVFAGVARALKPGGLFIF 142
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 42-134 1.99e-11

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 58.73  E-value: 1.99e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  42 LELGIGTGRIALPLVAS-GIEVHGIDSSPSMAEKLR--AKPGGDRIPVKIGNFADVDVQ-GSFSLIFIVFntFYGLLSQD 117
Cdd:pfam13649   2 LDLGCGTGRLTLALARRgGARVTGVDLSPEMLERARerAAEAGLNVEFVQGDAEDLPFPdGSFDLVVSSG--VLHHLPDP 79

                          90
                  ....*....|....*..
gi 1176253242 118 EQVLCFQNVANHLSENG 134
Cdd:pfam13649  80 DLEAALREIARVLKPGG 96
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 40-142 1.16e-08

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 51.66  E-value: 1.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  40 RALELGIGTGRIALPLV-ASGIEVHGIDSSPSMAEKLR---AKPGGDRIPVKIGNFADVDVQ--GSFSLIFIVFNTFYGL 113
Cdd:cd02440     1 RVLDLGCGTGALALALAsGPGARVTGVDISPVALELARkaaAALLADNVEVLKGDAEELPPEadESFDVIISDPPLHHLV 80

                          90       100
                  ....*....|....*....|....*....
gi 1176253242 114 LSQDEQvlcFQNVANHLSENGVFLIEAFV 142
Cdd:cd02440    81 EDLARF---LEEARRLLKPGGVLVLTLVL 106
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 32-100 2.36e-04

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 40.98  E-value: 2.36e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1176253242  32 LDDLAqGGRALELGIGTGRIALPLVASGIEVHGIDSSPSM----AEKLRAKPGGDRIpvkigNFA--DVD-VQGSF 100
Cdd:PRK07580   59 DGDLT-GLRILDAGCGVGSLSIPLARRGAKVVASDISPQMveeaRERAPEAGLAGNI-----TFEvgDLEsLLGRF 128
rADc smart00650
Ribosomal RNA adenine dimethylases;
29-113 8.66e-03

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 35.95  E-value: 8.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242   29 IRTLDDLAQGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAK-PGGDRIPVKIGNFADVDVqGSFSLIFIVF 107
Cdd:smart00650   5 IVRAANLRPGDTVLEIGPGKGALTEELLERAKRVTAIEIDPRLAPRLREKfAAADNLTVIHGDALKFDL-PKLQPYKVVG 83


                   ....*.
gi 1176253242  108 NTFYGL 113
Cdd:smart00650  84 NLPYNI 89
 
Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
14-138 1.55e-17

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 77.35  E-value: 1.55e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  14 ADIYDD------WYQTCEPGLIRTLDDLA--QGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAKPGGDRip 85
Cdd:COG4976    15 ADSYDAalvedlGYEAPALLAEELLARLPpgPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYDR-- 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1176253242  86 VKIGNFADVDVQ-GSFSLIfIVFNTFYGLlsqDEQVLCFQNVANHLSENGVFLI 138
Cdd:COG4976    93 LLVADLADLAEPdGRFDLI-VAADVLTYL---GDLAAVFAGVARALKPGGLFIF 142
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 14-144 3.75e-16

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 72.36  E-value: 3.75e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  14 ADIYDDWyqtcEPGLIRTLDDLA-QGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAKPGGDRIPVKIGNFA 92
Cdd:COG2227     4 PDARDFW----DRRLAALLARLLpAGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAELNVDFVQGDLE 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1176253242  93 DVDVQ-GSFSLIfIVFNTFYgLLSQDEQVLcfQNVANHLSENGVFLIEafVPN 144
Cdd:COG2227    80 DLPLEdGSFDLV-ICSEVLE-HLPDPAALL--RELARLLKPGGLLLLS--TPN 126
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 17-149 4.44e-16

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 73.80  E-value: 4.44e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  17 YDDWYQT----CEPGLIRTLDDLAQGGRALELGIGTGRIALPLVAS-GIEVHGIDSSPSM---AEKLRAKPGGDRIPVKI 88
Cdd:COG0500     2 WDSYYSDellpGLAALLALLERLPKGGRVLDLGCGTGRNLLALAARfGGRVIGIDLSPEAialARARAAKAGLGNVEFLV 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1176253242  89 GNFADVD--VQGSFSLIfIVFNTFYgLLSQDEQVLCFQNVANHLSENGVFLIEAFVPNPQYFD 149
Cdd:COG0500    82 ADLAELDplPAESFDLV-VAFGVLH-HLPPEEREALLRELARALKPGGVLLLSASDAAAALSL 142
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
37-139 2.26e-15

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 69.47  E-value: 2.26e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  37 QGGRALELGIGTGRIALPLVA--SGIEVHGIDSSPSMAEKLRAKpgGDRIPVKIGNFADVDVQGSFSLIFiVFNTFYGLl 114
Cdd:COG4106     1 PPRRVLDLGCGTGRLTALLAErfPGARVTGVDLSPEMLARARAR--LPNVRFVVADLRDLDPPEPFDLVV-SNAALHWL- 76

                          90       100
                  ....*....|....*....|....*
gi 1176253242 115 sqDEQVLCFQNVANHLSENGVFLIE 139
Cdd:COG4106    77 --PDHAALLARLAAALAPGGVLAVQ 99
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 11-157 3.48e-13

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 64.63  E-value: 3.48e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  11 EKCADIYDDWYQtcepgLIRTLDdLAQGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAK--PGGDRIPVKI 88
Cdd:COG2226     2 DRVAARYDGREA-----LLAALG-LRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERaaEAGLNVEFVV 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  89 GNFADVDVQ-GSFSLIFIVFntfyGLLSQDEQVLCFQNVANHLSENGVFLIEAFVPnPQYFDRGQFVRTA 157
Cdd:COG2226    76 GDAEDLPFPdGSFDLVISSF----VLHHLPDPERALAEIARVLKPGGRLVVVDFSP-PDLAELEELLAEA 140
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 42-134 1.99e-11

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 58.73  E-value: 1.99e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  42 LELGIGTGRIALPLVAS-GIEVHGIDSSPSMAEKLR--AKPGGDRIPVKIGNFADVDVQ-GSFSLIFIVFntFYGLLSQD 117
Cdd:pfam13649   2 LDLGCGTGRLTLALARRgGARVTGVDLSPEMLERARerAAEAGLNVEFVQGDAEDLPFPdGSFDLVVSSG--VLHHLPDP 79

                          90
                  ....*....|....*..
gi 1176253242 118 EQVLCFQNVANHLSENG 134
Cdd:pfam13649  80 DLEAALREIARVLKPGG 96
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 13-140 2.45e-10

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 57.25  E-value: 2.45e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  13 CAdIYDDWYQTCEPGLIRTLDDLAQ------GGRALELGIGTGRIALPLVAS-GIEVHGIDSSPSMAEKLRAK----PGG 81
Cdd:COG2230    22 CA-YFEDPDDTLEEAQEAKLDLILRklglkpGMRVLDIGCGWGGLALYLARRyGVRVTGVTLSPEQLEYARERaaeaGLA 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1176253242  82 DRIPVKIGNFADVDVQGSFSLIFIVFNTFYglLSQDEQVLCFQNVANHLSENGVFLIEA 140
Cdd:COG2230   101 DRVEVRLADYRDLPADGQFDAIVSIGMFEH--VGPENYPAYFAKVARLLKPGGRLLLHT 157
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 40-142 1.16e-08

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 51.66  E-value: 1.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  40 RALELGIGTGRIALPLV-ASGIEVHGIDSSPSMAEKLR---AKPGGDRIPVKIGNFADVDVQ--GSFSLIFIVFNTFYGL 113
Cdd:cd02440     1 RVLDLGCGTGALALALAsGPGARVTGVDISPVALELARkaaAALLADNVEVLKGDAEELPPEadESFDVIISDPPLHHLV 80

                          90       100
                  ....*....|....*....|....*....
gi 1176253242 114 LSQDEQvlcFQNVANHLSENGVFLIEAFV 142
Cdd:cd02440    81 EDLARF---LEEARRLLKPGGVLVLTLVL 106
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 42-138 1.61e-08

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 50.74  E-value: 1.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  42 LELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAKPGGDRIPVKIGNFADVDVQ-GSFSLIFIvfntFYGLLSQDEQV 120
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLTFVVGDAEDLPFPdNSFDLVLS----SEVLHHVEDPE 76

                          90
                  ....*....|....*...
gi 1176253242 121 LCFQNVANHLSENGVFLI 138
Cdd:pfam08241  77 RALREIARVLKPGGILII 94
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 38-149 3.89e-07

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 48.18  E-value: 3.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  38 GGRALELGIGTGRIAL---PLVASGIEVHGIDSSPSM---AEKLRAKPGGDRIPVKIGNFADVDVQ---GSFSLIFivfn 108
Cdd:pfam13847   4 GMRVLDLGCGTGHLSFelaEELGPNAEVVGIDISEEAiekARENAQKLGFDNVEFEQGDIEELPELledDKFDVVI---- 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1176253242 109 TFYGLLSQDEQVLCFQNVANHLSENGVFLIEAFVPNPQYFD 149
Cdd:pfam13847  80 SNCVLNHIPDPDKVLQEILRVLKPGGRLIISDPDSLAELPA 120
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 42-136 9.44e-07

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 45.82  E-value: 9.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  42 LELGIGTGRIALPLVAS--GIEVHGIDSSPSM----AEKLRAKPGGDRIPVKIGNFADVDVQG-SFSLIFIvFNTFYGLl 114
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAlpGLEYTGLDISPAAleaaRERLAALGLLNAVRVELFQLDLGELDPgSFDVVVA-SNVLHHL- 78

                          90       100
                  ....*....|....*....|..
gi 1176253242 115 sqDEQVLCFQNVANHLSENGVF 136
Cdd:pfam08242  79 --ADPRAVLRNIRRLLKPGGVL 98
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 24-166 5.61e-06

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 45.11  E-value: 5.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  24 CEPGLIRTLDDLAQGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAKpggdripVKIGNFADVDV---QGSF 100
Cdd:pfam13489   9 LADLLLRLLPKLPSPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSPIAIERALLN-------VRFDQFDEQEAavpAGKF 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1176253242 101 SLIfIVFNTFYGLLSQDEQvlcFQNVANHLSENGVFLIEAFVPNPQYFDRGQFVRTAKLEDDHVRL 166
Cdd:pfam13489  82 DVI-VAREVLEHVPDPPAL---LRQIAALLKPGGLLLLSTPLASDEADRLLLEWPYLRPRNGHISL 143
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 32-100 2.36e-04

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 40.98  E-value: 2.36e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1176253242  32 LDDLAqGGRALELGIGTGRIALPLVASGIEVHGIDSSPSM----AEKLRAKPGGDRIpvkigNFA--DVD-VQGSF 100
Cdd:PRK07580   59 DGDLT-GLRILDAGCGVGSLSIPLARRGAKVVASDISPQMveeaRERAPEAGLAGNI-----TFEvgDLEsLLGRF 128
PRK11207 PRK11207
tellurite resistance methyltransferase TehB;
18-103 2.43e-04

tellurite resistance methyltransferase TehB;


Pssm-ID: 183040  Cd Length: 197  Bit Score: 40.87  E-value: 2.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  18 DDWYQTCEPGLIRTLDDLAQ------GGRALELGIGTGRIALPLVASGIEVHGIDSSP---SMAEKLRAKPGGDRIPVKI 88
Cdd:PRK11207    5 DENYFTDKYGLTRTHSEVLEavkvvkPGKTLDLGCGNGRNSLYLAANGFDVTAWDKNPmsiANLERIKAAENLDNLHTAV 84

                          90
                  ....*....|....*
gi 1176253242  89 GNFADVDVQGSFSLI 103
Cdd:PRK11207   85 VDLNNLTFDGEYDFI 99
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 34-77 6.51e-04

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 40.16  E-value: 6.51e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1176253242  34 DLAQGGRALEL--GIGTgrIALPLVASGIEVHGIDSSPSMAEKLRA 77
Cdd:COG2265   230 DLTGGERVLDLycGVGT--FALPLARRAKKVIGVEIVPEAVEDARE 273
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 34-119 8.78e-04

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 39.36  E-value: 8.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  34 DLAQGGRALELGIGTGRIALpLVA---SGIEVHGIDSSPSMAEKLR----AKPGGDRIPVK---IGNFADVDVQGSFSLI 103
Cdd:COG4123    34 PVKKGGRVLDLGTGTGVIAL-MLAqrsPGARITGVEIQPEAAELARrnvaLNGLEDRITVIhgdLKEFAAELPPGSFDLV 112

                          90       100
                  ....*....|....*....|
gi 1176253242 104 fIV----FNTFYGLLSQDEQ 119
Cdd:COG4123   113 -VSnppyFKAGSGRKSPDEA 131
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
37-104 1.20e-03

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 38.73  E-value: 1.20e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1176253242  37 QGGRALELGIGTGRIAL-PLVASGIEVHGIDSSPSMAEKLR--AKPGGDRIPVKIGNFADVDVQGSFSLIF 104
Cdd:COG2263    45 EGKTVLDLGCGTGMLAIgAALLGAKKVVGVDIDPEALEIARenAERLGVRVDFIRADVTRIPLGGSVDTVV 115
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 28-138 2.39e-03

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 37.47  E-value: 2.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  28 LIRTLDDLAQGGRALELGIGTG----RIALPLVASGiEVHGIDSSPSMAEKLR---AKPG-GDRIPVKIGNFADVD---V 96
Cdd:COG4122     7 LLYLLARLLGAKRILEIGTGTGystlWLARALPDDG-RLTTIEIDPERAAIARenfARAGlADRIRLILGDALEVLprlA 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1176253242  97 QGSFSLIFIvfntfygllsqD---EQVL-CFQNVANHLSENGVFLI 138
Cdd:COG4122    86 DGPFDLVFI-----------DadkSNYPdYLELALPLLRPGGLIVA 120
PRK14968 PRK14968
putative methyltransferase; Provisional
 28-138 4.45e-03

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 36.80  E-value: 4.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242  28 LIRTLDDLAqGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAE--KLRAKPGGDR---IPVKIGN-FADVDvQGSFS 101
Cdd:PRK14968   15 LAENAVDKK-GDRVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVEcaKCNAKLNNIRnngVEVIRSDlFEPFR-GDKFD 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1176253242 102 LifIVFNTFYGLLSQDEQVLCFQNVA-------------------NHLSENGVFLI 138
Cdd:PRK14968   93 V--ILFNPPYLPTEEEEEWDDWLNYAlsggkdgrevidrfldevgRYLKPGGRILL 146
rADc smart00650
Ribosomal RNA adenine dimethylases;
29-113 8.66e-03

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 35.95  E-value: 8.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176253242   29 IRTLDDLAQGGRALELGIGTGRIALPLVASGIEVHGIDSSPSMAEKLRAK-PGGDRIPVKIGNFADVDVqGSFSLIFIVF 107
Cdd:smart00650   5 IVRAANLRPGDTVLEIGPGKGALTEELLERAKRVTAIEIDPRLAPRLREKfAAADNLTVIHGDALKFDL-PKLQPYKVVG 83


                   ....*.
gi 1176253242  108 NTFYGL 113
Cdd:smart00650  84 NLPYNI 89
PRK08317 PRK08317
hypothetical protein; Provisional
 29-87 9.05e-03

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 36.45  E-value: 9.05e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1176253242  29 IRTLDDLAQGGRALELGIGTGRIALPL---VASGIEVHGIDSSPSMAEKLRAKPGGDRIPVK 87
Cdd:PRK08317   11 TFELLAVQPGDRVLDVGCGPGNDARELarrVGPEGRVVGIDRSEAMLALAKERAAGLGPNVE 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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