|
Name |
Accession |
Description |
Interval |
E-value |
| URH1 |
COG1957 |
Inosine-uridine nucleoside N-ribohydrolase [Nucleotide transport and metabolism]; ... |
2-333 |
9.14e-53 |
|
Inosine-uridine nucleoside N-ribohydrolase [Nucleotide transport and metabolism]; Inosine-uridine nucleoside N-ribohydrolase is part of the Pathway/BioSystem: Pyrimidine salvage
Pssm-ID: 441560 [Multi-domain] Cd Length: 310 Bit Score: 176.11 E-value: 9.14e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 2 APRRIIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVL 81
Cdd:COG1957 1 MMRKVIIDTDPG-------IDDALALLLALASPEIDLLGITTVAGNVPLEQTTRNALKLLELAGRTDV---------PVA 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 82 RcgpfqptsGDPqRWLRQRREFASSPAGLAAWGRRLERAPVREEADRDvtgevppArLDDLVDDLR-SPERSTVVGIGPL 160
Cdd:COG1957 65 A--------GAA-RPLVRPLVTAEHVHGEDGLGGVDLPEPTRPPEPEH-------A-VDFIIETLRaAPGEVTLVALGPL 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 161 TNIARVLTEWDGASGRIDRIVVMGGALAFG---TMV-DTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWRAIv 236
Cdd:COG1957 128 TNLALALRKDPELAERIKRIVIMGGAFFVPgnvTPVaEFNIYVDPEAAKIVFASGIPITMVGLDVTHQALLTPEDLARL- 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 237 rrAAMKGPTAIATASAFDAwvspWLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKL-----VECPDG 311
Cdd:COG1957 207 --AALGTPLGRFLADLLDF----YLDFYRERYGLDGCPLHDPLAVAYLLDPELFTTRPAPVDVETDGELtrgqtVVDWRG 280
|
330 340
....*....|....*....|....*..
gi 1174556942 312 VP-----VDIVEAVDNEAMISLWERTV 333
Cdd:COG1957 281 VTgrppnARVALDVDAERFLDLLLERL 307
|
|
| IU_nuc_hydro |
pfam01156 |
Inosine-uridine preferring nucleoside hydrolase; |
6-324 |
2.41e-37 |
|
Inosine-uridine preferring nucleoside hydrolase;
Pssm-ID: 460086 [Multi-domain] Cd Length: 253 Bit Score: 134.26 E-value: 2.41e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 6 IIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVirvvggegsragggpsaspvlrcgp 85
Cdd:pfam01156 1 VIIDTDPG-------IDDALALLLALASPEIELLGITTVAGNVSLEQTTRNALRL------------------------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 86 fqptsgdpqrwlrqrrefasspagLAAWGRrlERAPVreeadrdVTGEVpparlddlvddLRSPERSTVVGIGPLTNIAR 165
Cdd:pfam01156 49 ------------------------LELGGR--DDIPV-------YAGEA-----------IREPGEVTLVATGPLTNLAL 84
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 166 VLTEWDGASGRIDRIVVMGGALAFG---TMV-DTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWRAIvrrAAM 241
Cdd:pfam01156 85 ALRLDPELAKKIKELVIMGGAFGVRgnvTPAaEFNIFVDPEAAKIVFTSGLPITMVPLDVTHQALLTPEDLERL---AAL 161
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 242 KGPTAIATASAFDAwvspWLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKL----------VECPDG 311
Cdd:pfam01156 162 GTPLGRFLADLLRF----YAEFYRERFGIDGPPLHDPLAVAVALDPELFTTRRLNVDVETTGGLtrgqtvvddrGGWGKP 237
|
330
....*....|...
gi 1174556942 312 VPVDIVEAVDNEA 324
Cdd:pfam01156 238 PNVRVATDVDVDR 250
|
|
| nuc_hydro_IU_UC_XIUA |
cd02651 |
nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, ... |
5-305 |
1.56e-36 |
|
nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. This group contains proteins similar to nucleoside hydrolases which hydrolyze both pyrimidine and purine ribonucleosides: the inosine-uridine preferring nucleoside hydrolase from Crithidia fasciculata, the inosine-uridine-xanthosine preferring nucleoside hydrolase RihC from Escherichia coli and the xanthosine-inosine-uridine-adenosine-preferring nucleoside hydrolase RihC from Salmonella enterica serovar Typhimurium. This group also contains proteins similar to the pyrimidine-specific uridine-cytidine preferring nucleoside hydrolases URH1 from Saccharomyces cerevisiae, E. coli RihA and E. coli RihB. E. coli RihA is equally efficient with uridine and cytidine, E. coli RihB prefers cytidine over uridine. S. cerevisiae URH1 prefers uridine over cytidine.
Pssm-ID: 239117 [Multi-domain] Cd Length: 302 Bit Score: 133.44 E-value: 1.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 5 RIIVDCDPGNgvpganvDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVLRcg 84
Cdd:cd02651 1 PIIIDCDPGH-------DDAVAILLALFHPELDLLGITTVAGNVPLEKTTRNALKLLTLLGRTDV---------PVAA-- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 85 pfqptsGDPQRWLRQRrEFASS---PAGLAawGRRLERAPVREEAdrdvtgevPPArLDDLVDDLR-SPERSTVVGIGPL 160
Cdd:cd02651 63 ------GAARPLVRPL-ITASDihgESGLD--GADLPPPPRRPED--------IHA-VDAIIDTLRaSPEPITLVATGPL 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 161 TNIARVLTEWDGASGRIDRIVVMGGALAFGTMVDT---NFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWRAIvr 237
Cdd:cd02651 125 TNIALLLRKYPELAERIKEIVLMGGALGRGNITPAaefNIFVDPEAAKIVFNSGIPITMVPLDVTHKALATPEVIERI-- 202
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1174556942 238 rAAMKGPTAIATASAFDAWVSPWlsyseATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKL 305
Cdd:cd02651 203 -RALGNPVGKMLAELLDFFAETY-----GSAFTEGPPLHDPCAVAYLLDPELFTTKRANVDVETEGEL 264
|
|
| PRK10768 |
PRK10768 |
ribonucleoside hydrolase RihC; Provisional |
4-305 |
1.92e-25 |
|
ribonucleoside hydrolase RihC; Provisional
Pssm-ID: 182713 [Multi-domain] Cd Length: 304 Bit Score: 103.84 E-value: 1.92e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 4 RRIIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCA--------SEVirvvggegsragggp 75
Cdd:PRK10768 3 LPIILDTDPG-------IDDAVAIAAALFAPELDLKLITTVAGNVSVEKTTRNAlkllhffnSDV--------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 76 sasPVLRcGPFQPTsgdpqrwLRQRREFAS--SPAGLAAW------GRRLERAPVreEADRDVTgevpparlddlvddLR 147
Cdd:PRK10768 61 ---PVAQ-GAAKPL-------VRPLRDAASvhGESGMEGYdfpehtRKPLSIPAV--EAMRDAL--------------MN 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 148 SPERSTVVGIGPLTNIARVLTEWDGASGRIDRIVVMGGALA---FGTMVDTNFAVDPRAARVVVRFGIPITIVPLDTTRT 224
Cdd:PRK10768 114 APEPVTLVAIGPLTNIALLLSTYPEVKPYIKRIVLMGGSAGrgnVTPNAEFNIAVDPEAAAIVFRSGIPIVMCGLDVTNQ 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 225 TCLTRDRWRAIvrraamkgPTAIATASAFDAWVSPWLSYSEATrpvdGMWVHDLVALVALAHPELVDSSQHRVDVRDDGK 304
Cdd:PRK10768 194 ALLTPDYLATL--------PELNRTGKMLHALFSHYRSGSMQT----GLRMHDVCAIAYLLRPELFTLKPCFVDVETQGE 261
|
.
gi 1174556942 305 L 305
Cdd:PRK10768 262 F 262
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| URH1 |
COG1957 |
Inosine-uridine nucleoside N-ribohydrolase [Nucleotide transport and metabolism]; ... |
2-333 |
9.14e-53 |
|
Inosine-uridine nucleoside N-ribohydrolase [Nucleotide transport and metabolism]; Inosine-uridine nucleoside N-ribohydrolase is part of the Pathway/BioSystem: Pyrimidine salvage
Pssm-ID: 441560 [Multi-domain] Cd Length: 310 Bit Score: 176.11 E-value: 9.14e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 2 APRRIIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVL 81
Cdd:COG1957 1 MMRKVIIDTDPG-------IDDALALLLALASPEIDLLGITTVAGNVPLEQTTRNALKLLELAGRTDV---------PVA 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 82 RcgpfqptsGDPqRWLRQRREFASSPAGLAAWGRRLERAPVREEADRDvtgevppArLDDLVDDLR-SPERSTVVGIGPL 160
Cdd:COG1957 65 A--------GAA-RPLVRPLVTAEHVHGEDGLGGVDLPEPTRPPEPEH-------A-VDFIIETLRaAPGEVTLVALGPL 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 161 TNIARVLTEWDGASGRIDRIVVMGGALAFG---TMV-DTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWRAIv 236
Cdd:COG1957 128 TNLALALRKDPELAERIKRIVIMGGAFFVPgnvTPVaEFNIYVDPEAAKIVFASGIPITMVGLDVTHQALLTPEDLARL- 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 237 rrAAMKGPTAIATASAFDAwvspWLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKL-----VECPDG 311
Cdd:COG1957 207 --AALGTPLGRFLADLLDF----YLDFYRERYGLDGCPLHDPLAVAYLLDPELFTTRPAPVDVETDGELtrgqtVVDWRG 280
|
330 340
....*....|....*....|....*..
gi 1174556942 312 VP-----VDIVEAVDNEAMISLWERTV 333
Cdd:COG1957 281 VTgrppnARVALDVDAERFLDLLLERL 307
|
|
| IU_nuc_hydro |
pfam01156 |
Inosine-uridine preferring nucleoside hydrolase; |
6-324 |
2.41e-37 |
|
Inosine-uridine preferring nucleoside hydrolase;
Pssm-ID: 460086 [Multi-domain] Cd Length: 253 Bit Score: 134.26 E-value: 2.41e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 6 IIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVirvvggegsragggpsaspvlrcgp 85
Cdd:pfam01156 1 VIIDTDPG-------IDDALALLLALASPEIELLGITTVAGNVSLEQTTRNALRL------------------------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 86 fqptsgdpqrwlrqrrefasspagLAAWGRrlERAPVreeadrdVTGEVpparlddlvddLRSPERSTVVGIGPLTNIAR 165
Cdd:pfam01156 49 ------------------------LELGGR--DDIPV-------YAGEA-----------IREPGEVTLVATGPLTNLAL 84
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 166 VLTEWDGASGRIDRIVVMGGALAFG---TMV-DTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWRAIvrrAAM 241
Cdd:pfam01156 85 ALRLDPELAKKIKELVIMGGAFGVRgnvTPAaEFNIFVDPEAAKIVFTSGLPITMVPLDVTHQALLTPEDLERL---AAL 161
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 242 KGPTAIATASAFDAwvspWLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKL----------VECPDG 311
Cdd:pfam01156 162 GTPLGRFLADLLRF----YAEFYRERFGIDGPPLHDPLAVAVALDPELFTTRRLNVDVETTGGLtrgqtvvddrGGWGKP 237
|
330
....*....|...
gi 1174556942 312 VPVDIVEAVDNEA 324
Cdd:pfam01156 238 PNVRVATDVDVDR 250
|
|
| nuc_hydro_IU_UC_XIUA |
cd02651 |
nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, ... |
5-305 |
1.56e-36 |
|
nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. This group contains proteins similar to nucleoside hydrolases which hydrolyze both pyrimidine and purine ribonucleosides: the inosine-uridine preferring nucleoside hydrolase from Crithidia fasciculata, the inosine-uridine-xanthosine preferring nucleoside hydrolase RihC from Escherichia coli and the xanthosine-inosine-uridine-adenosine-preferring nucleoside hydrolase RihC from Salmonella enterica serovar Typhimurium. This group also contains proteins similar to the pyrimidine-specific uridine-cytidine preferring nucleoside hydrolases URH1 from Saccharomyces cerevisiae, E. coli RihA and E. coli RihB. E. coli RihA is equally efficient with uridine and cytidine, E. coli RihB prefers cytidine over uridine. S. cerevisiae URH1 prefers uridine over cytidine.
Pssm-ID: 239117 [Multi-domain] Cd Length: 302 Bit Score: 133.44 E-value: 1.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 5 RIIVDCDPGNgvpganvDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVLRcg 84
Cdd:cd02651 1 PIIIDCDPGH-------DDAVAILLALFHPELDLLGITTVAGNVPLEKTTRNALKLLTLLGRTDV---------PVAA-- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 85 pfqptsGDPQRWLRQRrEFASS---PAGLAawGRRLERAPVREEAdrdvtgevPPArLDDLVDDLR-SPERSTVVGIGPL 160
Cdd:cd02651 63 ------GAARPLVRPL-ITASDihgESGLD--GADLPPPPRRPED--------IHA-VDAIIDTLRaSPEPITLVATGPL 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 161 TNIARVLTEWDGASGRIDRIVVMGGALAFGTMVDT---NFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWRAIvr 237
Cdd:cd02651 125 TNIALLLRKYPELAERIKEIVLMGGALGRGNITPAaefNIFVDPEAAKIVFNSGIPITMVPLDVTHKALATPEVIERI-- 202
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1174556942 238 rAAMKGPTAIATASAFDAWVSPWlsyseATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKL 305
Cdd:cd02651 203 -RALGNPVGKMLAELLDFFAETY-----GSAFTEGPPLHDPCAVAYLLDPELFTTKRANVDVETEGEL 264
|
|
| nuc_hydro_CaPnhB |
cd02650 |
NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes ... |
5-304 |
3.46e-28 |
|
NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.
Pssm-ID: 239116 [Multi-domain] Cd Length: 304 Bit Score: 111.21 E-value: 3.46e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 5 RIIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVLRcG 84
Cdd:cd02650 1 KLILDTDPG-------IDDAMALAYALAHPDVDLIGVTTVYGNVTIETATRNALALLELFGRPDV---------PVAE-G 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 85 PFQPTSGDPQRWLrqrrEFASSPAGLAawgrrlerapvreeadrDVTGEVPPARLDD------LVDDLRS-PERSTVVGI 157
Cdd:cd02650 64 AAKPLTRPPFRIA----TFVHGDNGLG-----------------DVELPAPPRQPEDesaadfLIELANEyPGELTLVAV 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 158 GPLTNIARVLTEWDGASGRIDRIVVMGGALAFG----TMVDTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDrWR 233
Cdd:cd02650 123 GPLTNLALALARDPDFAKLVKQVVVMGGAFTVPgnvtPAAEANIHGDPEAADIVFTAGADLTMVGLDVTTQTLLTRE-DL 201
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1174556942 234 AIVRRAAMKGPTAIATASAF--DAWVSPWLsyseatrpVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGK 304
Cdd:cd02650 202 DELRDSGGKAGQFLADMLDYyiDFYQESPG--------LRGCALHDPLAVAAAVDPSLFTTREGVVRVETEGP 266
|
|
| nuc_hydro |
cd00455 |
nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in ... |
6-303 |
1.37e-25 |
|
nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. This group contains eukaryotic, bacterial and archeal proteins similar to the inosine-uridine preferring nucleoside hydrolase from Crithidia fasciculata, the xanthosine-inosine-uridine-adenosine-preferring nucleoside hydrolase RihC from Salmonella enterica serovar Typhimurium, the purine-specific inosine-adenosine-guanosine-preferring nucleoside hydrolase from Trypanosoma vivax and, pyrimidine-specific uridine-cytidine preferring nucleoside hydrolases such as URH1 from Saccharomyces cerevisiae, RihA and RihB from Escherichia coli. Nucleoside hydrolases are of interest as a target for antiprotozoan drugs as, no nucleoside hydrolase activity or genes encoding these enzymes have been detected in humans and, parasitic protozoans lack de novo purine synthesis relying on nucleoside hydrolase to scavenge purine and/or pyrimidines from the environment.
Pssm-ID: 238257 [Multi-domain] Cd Length: 295 Bit Score: 103.95 E-value: 1.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 6 IIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVLRcGP 85
Cdd:cd00455 1 VILDTDPG-------IDDAFALMYALLHPEIELVGIVATYGNVTLEQATQNAAYLLELLGRLDI---------PVYA-GA 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 86 FQPTSGDPQRWLRQRREfasspaglaaWGRRLERAPVREEADrdvtgevPPARLDDLVDDLRS-PERSTVVGIGPLTNIA 164
Cdd:cd00455 64 TRPLTGEIPAAYPEIHG----------EGGLGLPIPPIIEAD-------DPEAVQLLIDLIRKyPDEITIVALGPLTNLA 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 165 RVL-TEWDGASgRIDRIVVMGGALAFGTMV----DTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWRAIVRRA 239
Cdd:cd00455 127 MAFiLDPDIKD-RVKEIVIMGGAFLVPGNVtpvaEANFYGDPEAANIVFNSAKNLTIVPLDVTNQAVLTPPMVERIFEQG 205
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1174556942 240 AMKGPTaIATASAFdawvspwlsYSEA--TRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDG 303
Cdd:cd00455 206 TSIGLL-IKPMIDY---------YYKAyqKPGIEGSPIHDPLAVAYLLNPSMFDYSKVPVDVDTDG 261
|
|
| PRK10768 |
PRK10768 |
ribonucleoside hydrolase RihC; Provisional |
4-305 |
1.92e-25 |
|
ribonucleoside hydrolase RihC; Provisional
Pssm-ID: 182713 [Multi-domain] Cd Length: 304 Bit Score: 103.84 E-value: 1.92e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 4 RRIIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCA--------SEVirvvggegsragggp 75
Cdd:PRK10768 3 LPIILDTDPG-------IDDAVAIAAALFAPELDLKLITTVAGNVSVEKTTRNAlkllhffnSDV--------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 76 sasPVLRcGPFQPTsgdpqrwLRQRREFAS--SPAGLAAW------GRRLERAPVreEADRDVTgevpparlddlvddLR 147
Cdd:PRK10768 61 ---PVAQ-GAAKPL-------VRPLRDAASvhGESGMEGYdfpehtRKPLSIPAV--EAMRDAL--------------MN 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 148 SPERSTVVGIGPLTNIARVLTEWDGASGRIDRIVVMGGALA---FGTMVDTNFAVDPRAARVVVRFGIPITIVPLDTTRT 224
Cdd:PRK10768 114 APEPVTLVAIGPLTNIALLLSTYPEVKPYIKRIVLMGGSAGrgnVTPNAEFNIAVDPEAAAIVFRSGIPIVMCGLDVTNQ 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 225 TCLTRDRWRAIvrraamkgPTAIATASAFDAWVSPWLSYSEATrpvdGMWVHDLVALVALAHPELVDSSQHRVDVRDDGK 304
Cdd:PRK10768 194 ALLTPDYLATL--------PELNRTGKMLHALFSHYRSGSMQT----GLRMHDVCAIAYLLRPELFTLKPCFVDVETQGE 261
|
.
gi 1174556942 305 L 305
Cdd:PRK10768 262 F 262
|
|
| rihA |
PRK10443 |
ribonucleoside hydrolase 1; Provisional |
3-305 |
2.05e-22 |
|
ribonucleoside hydrolase 1; Provisional
Pssm-ID: 182465 [Multi-domain] Cd Length: 311 Bit Score: 95.50 E-value: 2.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 3 PRRIIVDCDPGNgvpganvDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsaspvlr 82
Cdd:PRK10443 2 ALPIILDCDPGH-------DDAIALVLALASPELDVKAVTTSAGNQTPEKTLRNALRMLTLLNRTDI------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 83 cgpfqPTSGDPQRWLRQRREFASSPAGLAAWGrrlerAPVREEADRDVtgeVPPARLDDLVDDLR-SPERSTVVGIGPLT 161
Cdd:PRK10443 62 -----PVAGGAVKPLMRELIIADNVHGESGLD-----GPALPEPTFAP---QNCTAVELMAKTLReSAEPVTLVSTGPQT 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 162 NIARVLTEWDGASGRIDRIVVMGGALAFGT---MVDTNFAVDPRAARVVVRFGIPITIVPLDTT-RTTCLTRDrwraIVR 237
Cdd:PRK10443 129 NVALLLASHPELHSKIARIVIMGGAMGLGNwtpAAEFNIYVDPEAAEIVFQSGIPIVMAGLDVThKAQIMDED----IER 204
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1174556942 238 RAAMKGPTAIATASAFDAWVspwLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKL 305
Cdd:PRK10443 205 IRAIGNPVATIVAELLDFFM---EYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGEY 269
|
|
| nuc_hydro_CjNH |
cd02654 |
nuc_hydro_CjNH. Nucleoside hydrolases similar to Campylobacter jejuni nucleoside hydrolase. ... |
5-293 |
1.26e-20 |
|
nuc_hydro_CjNH. Nucleoside hydrolases similar to Campylobacter jejuni nucleoside hydrolase. This group contains eukaryotic and bacterial proteins similar to C. jejuni nucleoside hydrolase. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. C. jejuni nucleoside hydrolase is inactive against natural nucleosides or against common nucleoside analogues.
Pssm-ID: 239120 [Multi-domain] Cd Length: 318 Bit Score: 90.69 E-value: 1.26e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 5 RIIVDCDPGNGvpgANVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGyrcASEVIRVVGGEGSRagggpsaspvlrCG 84
Cdd:cd02654 1 KVILDNDIAMG---RDTDDGLALALLLWSPEVELLGLSAVSGNCWLSAV---TYNVLRMLELAGAD------------AI 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 85 PFQPTSGDP---QRWLRQRREfasSPAGLAAWGRRLERAPVREEADRDVTGEVPPARLDDLVDDLRS-PERSTVVGIGPL 160
Cdd:cd02654 63 PVYAGANTPlgrTNRAFHAWE---SLYGAYLWQGAWSPEYSDMYTNASIIRNASIPAALFMIEMVRKhPHEVSIVAAGPL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 161 TNIARVLTEWDGASGRIDRIVVMGGALAFGTMV-------DTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWR 233
Cdd:cd02654 140 TNLALALRIDPDFAPLAKELVIMGGYLDDIGEFvnrhyasDFNLIMDPEAASIVLTAPWKSITIPGNVTNRTCLTPEQIK 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1174556942 234 AIVRRAAMkgptaiatasaFDAWVSPWLSY-SEATRPVDGMWVHDLVALVALAHPELVDSS 293
Cdd:cd02654 220 ADDPLRDF-----------IRETLDLPIDYaKEFVGTGDGLPMWDELASAVALDPELATSS 269
|
|
| nuc_hydro_CeIAG |
cd02649 |
nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring ... |
4-305 |
6.21e-20 |
|
nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. This group contains eukaryotic, bacterial and archeal proteins similar to the purine-preferring nucleoside hydrolase (IAG-NH) from C. elegans and the salivary purine nucleosidase from Aedes aegypti. C. elegans IAG-NH exhibits a high affinity for the substrate analogue p-nitrophenylriboside (p-NPR).
Pssm-ID: 239115 [Multi-domain] Cd Length: 306 Bit Score: 88.47 E-value: 6.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 4 RRIIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVLRc 83
Cdd:cd02649 1 RKLIIDTDCG-------GDDAWALLMALASPNVEVLAITCVHGNTNVEQVVKNALRVLEACGRRDI---------PVYR- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 84 gpfqptsGDPQRWLRQRRE----FASSpaGLAAWGrrLERAPVREEADRdvTGEVpparlDDLVDDLRSPERS-TVVGIG 158
Cdd:cd02649 64 -------GASKPLLGPGPTaayfHGKD--GFGDVG--FPEPKDELELQK--EHAV-----DAIIRLVREYPGEiTLVALG 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 159 PLTNIARVLTEWDGASGRIDRIVVMGGAlAFG----TMV-DTNFAVDPRAARVVV-RFGIPITIVPLDTTRTTCLTRDRW 232
Cdd:cd02649 126 PLTNLALAYRLDPSLPQKIKRLYIMGGN-REGvgntTPAaEFNFHVDPEAAHIVLnSFGCPITIVPWETTLLAFPLDWEF 204
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1174556942 233 raivrraAMKGPTAIATASAFDAwVSPwLSYSEA-TRPVDGMWVH-DLVALVALAHPELVDSSQ-HRVDVRDDGKL 305
Cdd:cd02649 205 -------EDKWANRLEKALFAES-LNR-REYAFAsEGLGGDGWVPcDALAVAAALDPSIITRRLtYAVDVELHGEL 271
|
|
| nuc_hydro_3 |
cd02653 |
NH_3: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial ... |
6-306 |
7.98e-20 |
|
NH_3: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial proteins similar to nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.
Pssm-ID: 239119 [Multi-domain] Cd Length: 320 Bit Score: 88.59 E-value: 7.98e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 6 IIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGegsragggpSASPVLRcGP 85
Cdd:cd02653 2 VIIDCDPG-------IDDALALLYLLASPDLDVVGITTTAGNVPVEQVAANALGVLELLGR---------TDIPVYL-GA 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 86 FQPTsgdpQRWLRQRREFaSSPAGLaawGRRLERAPVREEADRDVTGEvpparlddLVDDLRSPERSTVVGIGPLTNIAR 165
Cdd:cd02653 65 DKPL----AGPLTTAQDT-HGPDGL---GYAELPASTRTLSDESAAQA--------WVDLARAHPDLIGLATGPLTNLAL 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 166 VLTEwDGASGR-IDRIVVMGGALAF--GTMVDT--NFAVDPRAARVVV----RFGIPITIVPLDTTRTTCLTRDrWRAIV 236
Cdd:cd02653 129 ALRE-EPELPRlLRRLVIMGGAFNSrgNTSPVAewNYWVDPEAAKEVLaafgGHPVRPTICGLDVTRAVVLTPN-LLERL 206
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 237 RRAAMKGPTAIATASAFdawvspWLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDGKLV 306
Cdd:cd02653 207 ARAKDSVGAFIEDALRF------YFEFHWAYGHGYGAVIHDPLAAAVALNPNLARGRPAYVDVECTGVLT 270
|
|
| nuc_hydro_TvIAG |
cd02647 |
nuc_hydro_ TvIAG: Nucleoside hydrolases similar to the Inosine-adenosine-guanosine-preferring ... |
4-322 |
4.37e-19 |
|
nuc_hydro_ TvIAG: Nucleoside hydrolases similar to the Inosine-adenosine-guanosine-preferring nucleoside hydrolase from Trypanosoma vivax. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. Nucleoside hydrolases vary in their substrate specificity. This group contains eukaryotic and bacterial proteins similar to the purine specific inosine-adenosine-guanosine-preferring nucleoside hydrolase (IAG-NH) from T. vivax. T. vivax IAG-NH is of the order of a thousand to ten thousand fold more specific towards the naturally occurring purine nucleosides, than towards the pyrimidine nucleosides.
Pssm-ID: 239113 [Multi-domain] Cd Length: 312 Bit Score: 86.32 E-value: 4.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 4 RRIIVDCDpgngvpgANVDDALALAYALRSPLVDVGAVwtVFGNTPPDLGYRCASEVIRvvggEGSRAGGGPSASPVLRC 83
Cdd:cd02647 1 KNVIFDHD-------GNVDDLVALLLLLKNEKVDLKGI--GVSGIDADCYVEPAVSVTR----KLIDRLGQRDAIPVGKG 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 84 GpfqptsgdpqrwLRQRREFASSPAGLAAWgrRLERAPVREEADRDVTGEVPPARLDDLVD-DLRSPERSTVVGIGPLTN 162
Cdd:cd02647 68 G------------SRAVNPFPRSWRRDAAF--SVDHLPILNERYTVETPLAEETAQLVLIEkIKASLEPVTLLVTGPLTN 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 163 IARVLTEWDGASGRIDRIVVMGGAL-----AFGTMVDT----NFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDRWR 233
Cdd:cd02647 134 LARALDSDPDISSNIEEVYIMGGGVdapgnVFTPPSNGtaefNIFWDPLAAKTVFDSGLKITLVPLDATNTVPLTREFLE 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 234 AIVRRAAMKGPTAIATASAFDAWVSPWLSYSEATrpvdgMWvhDLVALVALAHPELVDSSQHR-----VDVRDDGKLVEC 308
Cdd:cd02647 214 TDRQRFAAQRLPASDLAGQGYALVKPLEFNSTYY-----MW--DVLTTLVLGAKEVDNTKESLilevdTDGLSAGQTVTS 286
|
330
....*....|....
gi 1174556942 309 PDGVPVDIVEAVDN 322
Cdd:cd02647 287 PNGRPLTLVTSNNS 300
|
|
| PLN02717 |
PLN02717 |
uridine nucleosidase |
4-303 |
7.58e-19 |
|
uridine nucleosidase
Pssm-ID: 178319 [Multi-domain] Cd Length: 316 Bit Score: 85.81 E-value: 7.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 4 RRIIVDCDPGngvpganVDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGSragggpsasPVLRc 83
Cdd:PLN02717 1 KKLIIDTDPG-------IDDAMAILMALRSPEVEVIGLTTIFGNVTTKLATRNALHLLEMAGRPDV---------PVAE- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 84 GPFQPTSGDPQRWLRqrrEFASSPAGLaawGRRLERAPVREEADRDVTgevpparlDDLVDDLR-SPERSTVVGIGPLTN 162
Cdd:PLN02717 64 GSHEPLKGGTKPRIA---DFVHGSDGL---GNTNLPPPKGKKIEKSAA--------EFLVEKVSeYPGEVTVVALGPLTN 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 163 IARVLTEWDGASGRIDRIVVMGGALAFGTMV----DTNFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTrDRWRAIVRR 238
Cdd:PLN02717 130 LALAIKLDPSFAKKVGQIVVLGGAFFVNGNVnpaaEANIFGDPEAADIVFTSGADITVVGINVTTQVVLT-DADLEELRD 208
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1174556942 239 AAMKGPTAIATASAFdawvspWLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDVRDDG 303
Cdd:PLN02717 209 SKGKYAQFLCDICKF------YRDWHRKSYGIDGIYLHDPTALLAAVRPSLFTYKEGVVRVETEG 267
|
|
| rihB |
PRK09955 |
ribosylpyrimidine nucleosidase; |
1-299 |
1.98e-17 |
|
ribosylpyrimidine nucleosidase;
Pssm-ID: 182166 [Multi-domain] Cd Length: 313 Bit Score: 81.53 E-value: 1.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 1 MAPRRIIVDCDPGNgvpganvDDALALAYALRSPLVDVGAVWTVFGNTPPDLGYRCASEVIRVVGGEGsragggpsasPV 80
Cdd:PRK09955 1 MEKRKIILDCDPGH-------DDAIAMMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINV----------PV 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 81 LrcgpfqptSGDPQRWLRQR--REFASSPAGLaawgrrleRAPVREEADRDVTGEVPPARLDDLVddLRSPERSTVVGIG 158
Cdd:PRK09955 64 Y--------AGMPQPIMRQQivADNIHGETGL--------DGPVFEPLTRQAESTHAVKYIIDTL--MASDGDITLVPVG 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 159 PLTNIARVLTEWDGASGRIDRIVVMGGALAFGTMVDT---NFAVDPRAARVVVRFGIPITIVPLDTTRTTCLTRDrwrAI 235
Cdd:PRK09955 126 PLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSaefNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPD---VI 202
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1174556942 236 VRRAAMKGPtaiaTASAFDAWVSPWLSYSEATRPVDGMWVHDLVALVALAHPELVDSSQHRVDV 299
Cdd:PRK09955 203 ARMERAGGP----AGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEV 262
|
|
| nuc_hydro_1 |
cd02648 |
NH_1: A subgroup of nucleoside hydrolases. This group contains fungal proteins similar to ... |
3-286 |
3.70e-15 |
|
NH_1: A subgroup of nucleoside hydrolases. This group contains fungal proteins similar to nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.
Pssm-ID: 239114 [Multi-domain] Cd Length: 367 Bit Score: 75.69 E-value: 3.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 3 PRRIIVDCDPGngvpganVDDALALAYALRSP-LVDVGAVWTVFGNTPPDLGYRCASEVIRV----VGGEGSRAGGGPSA 77
Cdd:cd02648 1 PHPIIIDTDPG-------VDDVLAILLALSSPeEVDVALISLTFGNTTLDHALRNVLRLFHVlereRAWRATPGVRYRAF 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 78 S-----PVLRCGPFQPTSGDpqrwlRQRREFASSPAGLAAWGRRL-ERAPVREEADRDVTGEVPPARL--DDLVDDLR-S 148
Cdd:cd02648 74 SadaekPIVASGSDQPLEGE-----RLTASYFHGRDGLSGVHWLHpDFTPVETWIPEIVAPLTPSDKPayDVILDILReE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 149 PERS-TVVGIGPLTNIARVLTEWDGASGRIDRIVVMGGALAF----GTMVDTNFAVDPRAARVVVRFG----------IP 213
Cdd:cd02648 149 PDHTvTIAALGPLTNLAAAARKDPETFAKVGEVVVMGGAIDVpgntSPVAEFNCFADPYAAAVVIDEPpstapearrkLP 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 214 ITIVPLDTTRTTCLTRDRWR--AIVRRAAMKgptaiaTASAFDAWVSPWLSYSEATRP---------VDGMWVHDLVALV 282
Cdd:cd02648 229 LQVFPLDITTGHTLPYSSLFatYVTPRDAPE------RGSPLARWLEHVFISTFLTHPraftpeeflPDRSELFEMHDPL 302
|
....
gi 1174556942 283 ALAH 286
Cdd:cd02648 303 AVWY 306
|
|
| nuc_hydro_2 |
cd02652 |
NH_2: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial ... |
153-218 |
1.28e-04 |
|
NH_2: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial proteins similar to nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.
Pssm-ID: 239118 [Multi-domain] Cd Length: 293 Bit Score: 43.26 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1174556942 153 TVVGIGPLTNIARVL-TEWDGASG------RIDRIVVMGGALAF----GTMVDTNFAVDPRAARVVVR----FGIPITIV 217
Cdd:cd02652 112 TIVSIGPLTNLAALLdADADPLTGpelvrqKVKRLVVMGGAFYDpdgnVQHREYNFVTDPKAAQRVAGraqhLGIPVRIV 191
|
.
gi 1174556942 218 P 218
Cdd:cd02652 192 W 192
|
|
| |
