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Conserved domains on  [gi|1172943054|ref|WP_081007020|]
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IS1 family transposase [Piscirickettsia salmonis]

Protein Classification

IS1-like element transposase( domain architecture ID 1750064)

IS1-like element transposase acting on a specific type of insertion sequences (IS), the simplest class of procaryotic transposable elements which are capable of integrating into numerous sites within genomes via a transposition pathway independent of homologous re combination.

Gene Ontology:  GO:0006313

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS1 super family cl41321
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 6-95 1.39e-35

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


The actual alignment was detected with superfamily member NF033558:

Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 119.68  E-value: 1.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172943054   6 IELDEMWSFVGHKKNQRWLWHAIDHSTRKILAYHFGRRKDEALIALKSKLSSFNIRYYYTDDWGSYQRIVPEDSHFIGKK 85
Cdd:NF033558   98 CELDELWTFVGNKKNKRWLWYAYDRKTKRILAYVFGDRSAETFRKLWALLKPFKIGFYCTDHWKVYAEFLPDEKHLVSKG 177

                          90
                  ....*....|
gi 1172943054  86 NTQAIERKHL 95
Cdd:NF033558  178 ETQRIERENL 187
 
Name Accession Description Interval E-value
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 6-95 1.39e-35

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 119.68  E-value: 1.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172943054   6 IELDEMWSFVGHKKNQRWLWHAIDHSTRKILAYHFGRRKDEALIALKSKLSSFNIRYYYTDDWGSYQRIVPEDSHFIGKK 85
Cdd:NF033558   98 CELDELWTFVGNKKNKRWLWYAYDRKTKRILAYVFGDRSAETFRKLWALLKPFKIGFYCTDHWKVYAEFLPDEKHLVSKG 177

                          90
                  ....*....|
gi 1172943054  86 NTQAIERKHL 95
Cdd:NF033558  178 ETQRIERENL 187
InsB COG1662
Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];
6-95 3.49e-34

Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];


Pssm-ID: 441268 [Multi-domain]  Cd Length: 193  Bit Score: 115.95  E-value: 3.49e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172943054   6 IELDEMWSFVGHKKNQRWLWHAIDHSTRKILAYHFGRRKDEALIALKSKLSSFNIRYYYTDDWGSYQRIVPEDSHFIGKK 85
Cdd:COG1662    64 VEVDELWTFVGSKKNKVWIWYAVDRDTGRIVAFVVGDRDKKTARKLWEKLKPFEIAVIYTDGWKAYASLIPEKRHVVSKG 143

                          90
                  ....*....|
gi 1172943054  86 NTQAIERKHL 95
Cdd:COG1662   144 YTNHIERNNL 153
DDE_Tnp_IS1 pfam03400
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
 7-95 4.46e-28

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


Pssm-ID: 281403  Cd Length: 131  Bit Score: 98.50  E-value: 4.46e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172943054   7 ELDEMWSFVGHKKNQRWLWHAIDHSTRKILAYHFGRRKDEALIALKSKLSSFNIRYYYTDDWGSYQRIVPEDSHFIGKKN 86
Cdd:pfam03400   6 ELDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPFDIGILMSDDWGLYERELKGDKHLIGKIF 85


                  ....*....
gi 1172943054  87 TQAIERKHL 95
Cdd:pfam03400  86 TQRIERHNL 94
 
Name Accession Description Interval E-value
transpos_IS1 NF033558
IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family ...
 6-95 1.39e-35

IS1 family transposase; Proteins of this family are DDE transposases encoded by the IS1 family elements usually through a translational frameshift mechanism.


Pssm-ID: 468085 [Multi-domain]  Cd Length: 199  Bit Score: 119.68  E-value: 1.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172943054   6 IELDEMWSFVGHKKNQRWLWHAIDHSTRKILAYHFGRRKDEALIALKSKLSSFNIRYYYTDDWGSYQRIVPEDSHFIGKK 85
Cdd:NF033558   98 CELDELWTFVGNKKNKRWLWYAYDRKTKRILAYVFGDRSAETFRKLWALLKPFKIGFYCTDHWKVYAEFLPDEKHLVSKG 177

                          90
                  ....*....|
gi 1172943054  86 NTQAIERKHL 95
Cdd:NF033558  178 ETQRIERENL 187
InsB COG1662
Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];
6-95 3.49e-34

Transposase and inactivated derivatives, IS1 family [Mobilome: prophages, transposons];


Pssm-ID: 441268 [Multi-domain]  Cd Length: 193  Bit Score: 115.95  E-value: 3.49e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172943054   6 IELDEMWSFVGHKKNQRWLWHAIDHSTRKILAYHFGRRKDEALIALKSKLSSFNIRYYYTDDWGSYQRIVPEDSHFIGKK 85
Cdd:COG1662    64 VEVDELWTFVGSKKNKVWIWYAVDRDTGRIVAFVVGDRDKKTARKLWEKLKPFEIAVIYTDGWKAYASLIPEKRHVVSKG 143

                          90
                  ....*....|
gi 1172943054  86 NTQAIERKHL 95
Cdd:COG1662   144 YTNHIERNNL 153
DDE_Tnp_IS1 pfam03400
IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This ...
 7-95 4.46e-28

IS1 transposase; Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.


Pssm-ID: 281403  Cd Length: 131  Bit Score: 98.50  E-value: 4.46e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172943054   7 ELDEMWSFVGHKKNQRWLWHAIDHSTRKILAYHFGRRKDEALIALKSKLSSFNIRYYYTDDWGSYQRIVPEDSHFIGKKN 86
Cdd:pfam03400   6 ELDEQWGFVGAKARQHWLFYAYDRKRGGVLAHTFGERTDATCGELLALLSPFDIGILMSDDWGLYERELKGDKHLIGKIF 85


                  ....*....
gi 1172943054  87 TQAIERKHL 95
Cdd:pfam03400  86 TQRIERHNL 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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