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Conserved domains on  [gi|1167234569|gb|OQA64665|]
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Ascorbate-specific phosphotransferase enzyme IIA component [Spirochaetes bacterium ADurb.Bin269]

Protein Classification

PTS sugar transporter subunit IIA( domain architecture ID 76)

PTS sugar transporter subunit IIA is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system that catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane

CATH:  3.40.930.10
Gene Ontology:  GO:1902495|GO:0009401|GO:0016310|GO:0016301|GO:0008643
PubMed:  11532441|10393270
SCOP:  4001876

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTS_IIA_fru super family cl00163
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ...
 1-150 2.98e-49

PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.


The actual alignment was detected with superfamily member PRK10372:

Pssm-ID: 469635 [Multi-domain]  Cd Length: 154  Bit Score: 155.52  E-value: 2.98e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   1 MGFFEFLKSNGTIALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDGCVRNGPYFVIGPGLAMPHARPENGVIKTGY 80
Cdd:PRK10372    1 MKLRDSLAENKSIRLQAEAETWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  81 ALVTLKKGVEFGDGENDPVDVLVFMAAKDSASHTEEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLSRA 150
Cdd:PRK10372   81 ALVTLKKPLEFNHEDNDPVDILITMAAVDANTHQEVGIMQIVNLFEDEANFDRLRACRTEQEVLDLIDRT 150
 
Name Accession Description Interval E-value
PRK10372 PRK10372
PTS ascorbate transporter subunit IIA;
1-150 2.98e-49

PTS ascorbate transporter subunit IIA;


Pssm-ID: 182417 [Multi-domain]  Cd Length: 154  Bit Score: 155.52  E-value: 2.98e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   1 MGFFEFLKSNGTIALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDGCVRNGPYFVIGPGLAMPHARPENGVIKTGY 80
Cdd:PRK10372    1 MKLRDSLAENKSIRLQAEAETWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  81 ALVTLKKGVEFGDGENDPVDVLVFMAAKDSASHTEEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLSRA 150
Cdd:PRK10372   81 ALVTLKKPLEFNHEDNDPVDILITMAAVDANTHQEVGIMQIVNLFEDEANFDRLRACRTEQEVLDLIDRT 150
PTS_IIA_fru cd00211
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ...
 9-147 1.35e-34

PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.


Pssm-ID: 238129 [Multi-domain]  Cd Length: 136  Bit Score: 117.66  E-value: 1.35e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   9 SNGTIALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDgCVRNGPYFvIGPGLAMPHARPEnGVIKTGYALVTLKKG 88
Cdd:cd00211     2 TKENIRLNLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLE-REKEGSTG-IGNGIAIPHAKSE-AVKKPGIAVLRLKEP 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1167234569  89 VEFGDGENDPVDVLVFMAAKDSASHtEEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLL 147
Cdd:cd00211    79 VDFGSLDGQPVHLIFLLAAPDSNEH-LKALSQLARLLSDEEFVEQLLNAQSKEEILALL 136
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
 1-151 1.65e-33

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 115.33  E-value: 1.65e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   1 MGFFEFLKSNgTIALDMEAADWKDAIRKGGSLLLQAGCCDGK--YVEAMIDGCVRNGPYfvIGPGLAMPHARPEnGVIKT 78
Cdd:COG1762     1 MMLSDLLTPE-LILLDLEASSKEEAIEELAELLAEKGYVLDKeeYLEALLEREELGSTG--IGPGIAIPHARPE-GVKKP 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1167234569  79 GYALVTLKKGVEFGDGENDPVDVLVFMAAKDSASHTE-EAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLSRAE 151
Cdd:COG1762    77 GIAVARLKEPVDFGAMDGEPVDLVFLLAAPEDDSEEHlKLLAELARLLSDEEFREKLLNAKSPEEILELLKEAE 150
PTS_EIIA_2 pfam00359
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
13-148 1.95e-30

Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;


Pssm-ID: 459780 [Multi-domain]  Cd Length: 139  Bit Score: 107.29  E-value: 1.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  13 IALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDgcvR---NGPYfvIGPGLAMPHARPEnGVIKTGYALVTLKKGV 89
Cdd:pfam00359   7 IFLNLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILE---RekeGSTG--IGNGIAIPHARSE-AVKKPGIAVLTLKEPV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1167234569  90 EFGDGENDPVDVLVFMAAKDSASHTEEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLS 148
Cdd:pfam00359  81 DFGSEDGKPVKLIFLLAAPDNEASHLKILSQLARLLQDEEFVEKLLKAKDPEEILEILK 139
fruA TIGR00848
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family ...
 60-124 2.31e-05

PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273298 [Multi-domain]  Cd Length: 129  Bit Score: 41.49  E-value: 2.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1167234569  60 IGPGLAMPHARpENGVIKTGYALVTLKKGVEFGDGENDPVDvLVFMAA--KDSASHTE-EAMSQIAGF 124
Cdd:TIGR00848  54 IGDGVAIPHAK-SAAVKQPFVAIARLVKGVDWQSLDGKPVK-LIFLIAvpKDEAGNTHlKALSQLARL 119
 
Name Accession Description Interval E-value
PRK10372 PRK10372
PTS ascorbate transporter subunit IIA;
1-150 2.98e-49

PTS ascorbate transporter subunit IIA;


Pssm-ID: 182417 [Multi-domain]  Cd Length: 154  Bit Score: 155.52  E-value: 2.98e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   1 MGFFEFLKSNGTIALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDGCVRNGPYFVIGPGLAMPHARPENGVIKTGY 80
Cdd:PRK10372    1 MKLRDSLAENKSIRLQAEAETWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  81 ALVTLKKGVEFGDGENDPVDVLVFMAAKDSASHTEEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLSRA 150
Cdd:PRK10372   81 ALVTLKKPLEFNHEDNDPVDILITMAAVDANTHQEVGIMQIVNLFEDEANFDRLRACRTEQEVLDLIDRT 150
PTS_IIA_fru cd00211
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ...
 9-147 1.35e-34

PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.


Pssm-ID: 238129 [Multi-domain]  Cd Length: 136  Bit Score: 117.66  E-value: 1.35e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   9 SNGTIALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDgCVRNGPYFvIGPGLAMPHARPEnGVIKTGYALVTLKKG 88
Cdd:cd00211     2 TKENIRLNLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLE-REKEGSTG-IGNGIAIPHAKSE-AVKKPGIAVLRLKEP 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1167234569  89 VEFGDGENDPVDVLVFMAAKDSASHtEEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLL 147
Cdd:cd00211    79 VDFGSLDGQPVHLIFLLAAPDSNEH-LKALSQLARLLSDEEFVEQLLNAQSKEEILALL 136
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
 1-151 1.65e-33

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 115.33  E-value: 1.65e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   1 MGFFEFLKSNgTIALDMEAADWKDAIRKGGSLLLQAGCCDGK--YVEAMIDGCVRNGPYfvIGPGLAMPHARPEnGVIKT 78
Cdd:COG1762     1 MMLSDLLTPE-LILLDLEASSKEEAIEELAELLAEKGYVLDKeeYLEALLEREELGSTG--IGPGIAIPHARPE-GVKKP 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1167234569  79 GYALVTLKKGVEFGDGENDPVDVLVFMAAKDSASHTE-EAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLSRAE 151
Cdd:COG1762    77 GIAVARLKEPVDFGAMDGEPVDLVFLLAAPEDDSEEHlKLLAELARLLSDEEFREKLLNAKSPEEILELLKEAE 150
cmtB PRK09854
PTS mannitol transporter subunit IIA;
12-150 1.83e-31

PTS mannitol transporter subunit IIA;


Pssm-ID: 182114 [Multi-domain]  Cd Length: 147  Bit Score: 110.08  E-value: 1.83e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  12 TIALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDGCVRNGPYFVIGPGLAMPHARPENGVIKTGYALVTLKKGVEF 91
Cdd:PRK09854   11 SISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQAIKDSTINNGPYYILAPGVAMPHARPECGALKTGMSLTLLEQGVYF 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1167234569  92 gDGENDPVDVLVFMAAKDSASHTE--EAMSQIagFCDNlDWLMELRVAKDVKSVVDLLSRA 150
Cdd:PRK09854   91 -PGNDEPIKLLIGLSAADADSHIGaiQALSEL--LCEE-EILEQLLTASSEKQLADIISRG 147
PTS_EIIA_2 pfam00359
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
13-148 1.95e-30

Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;


Pssm-ID: 459780 [Multi-domain]  Cd Length: 139  Bit Score: 107.29  E-value: 1.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  13 IALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDgcvR---NGPYfvIGPGLAMPHARPEnGVIKTGYALVTLKKGV 89
Cdd:pfam00359   7 IFLNLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILE---RekeGSTG--IGNGIAIPHARSE-AVKKPGIAVLTLKEPV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1167234569  90 EFGDGENDPVDVLVFMAAKDSASHTEEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLS 148
Cdd:pfam00359  81 DFGSEDGKPVKLIFLLAAPDNEASHLKILSQLARLLQDEEFVEKLLKAKDPEEILEILK 139
MtlA2 COG4668
Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and ...
 13-151 3.88e-23

Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism];


Pssm-ID: 443705 [Multi-domain]  Cd Length: 143  Bit Score: 88.68  E-value: 3.88e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  13 IALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDgcvR---NGPYfvIGPGLAMPHARPE--NGVIKTGYALVTLKK 87
Cdd:COG4668     9 IRLNASAANKEEAIRLAGQLLVEAGYVEPEYIDAMLE---ReaqVSTY--LGNGIAIPHGTNEakDLVLKTGISVLQFPD 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1167234569  88 GVEFGDGEndPVDVLVFMAAKDSAsHTeEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLSRAE 151
Cdd:COG4668    84 GVDWGDGN--TVYLVIGIAAKSDE-HL-EILRQLARVLSDEENVEKLAKATDAEEILALLTGEN 143
PRK15083 PRK15083
PTS system mannitol-specific transporter subunit IICBA; Provisional
 13-148 1.41e-10

PTS system mannitol-specific transporter subunit IICBA; Provisional


Pssm-ID: 237905 [Multi-domain]  Cd Length: 639  Bit Score: 58.14  E-value: 1.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  13 IALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDGCVRNGPYfvIGPGLAMPHARPE--NGVIKTGYALVTLKKGVE 90
Cdd:PRK15083  502 IFLGLKAATKEEAIRFAGEQLVKGGYVEPEYVDAMLDREKLTSTY--LGESIAVPHGTVEakDRVLKTGVVFCQYPEGVR 579

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1167234569  91 FGDGENDPVDVLVFMAAKDSaSHTeEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLS 148
Cdd:PRK15083  580 FGEEEDDIARLVIGIAARNN-EHI-QVITSLTNALDDESVIERLAHTTSVDEVLELLA 635
PRK11109 PRK11109
fused PTS fructose transporter subunit IIA/HPr protein;
13-94 4.33e-06

fused PTS fructose transporter subunit IIA/HPr protein;


Pssm-ID: 236849 [Multi-domain]  Cd Length: 375  Bit Score: 44.94  E-value: 4.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569  13 IALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDGCVRNGPYfvIGPGLAMPHARPE--NGVIKTGYALVTLKKGVE 90
Cdd:PRK11109    9 IHLGQQAGNKEEAIRQVAAALTQAGNVAEGYVDGMLAREQQTSTF--LGNGIAIPHGTTDtrDLVLKTGVQVFQFPQGVT 86


                  ....
gi 1167234569  91 FGDG 94
Cdd:PRK11109   87 WGDG 90
fruA TIGR00848
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family ...
 60-124 2.31e-05

PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273298 [Multi-domain]  Cd Length: 129  Bit Score: 41.49  E-value: 2.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1167234569  60 IGPGLAMPHARpENGVIKTGYALVTLKKGVEFGDGENDPVDvLVFMAA--KDSASHTE-EAMSQIAGF 124
Cdd:TIGR00848  54 IGDGVAIPHAK-SAAVKQPFVAIARLVKGVDWQSLDGKPVK-LIFLIAvpKDEAGNTHlKALSQLARL 119
nitro_reg_IIA TIGR01419
PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of ...
 60-123 2.38e-04

PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of about 160 residues closely related to the fructose-specific phosphotransferase (PTS) system IIA component. It is a regulatory protein found only in species with a phosphoenolpyruvate-protein phosphotransferase (enzyme I of PTS systems) and an HPr-like phosphocarrier protein, but not all species have a IIC-like permease. Members of this family are found in Proteobacteria, Chlamydia, and the spirochete Treponema pallidum. [Signal transduction, PTS]


Pssm-ID: 162350 [Multi-domain]  Cd Length: 145  Bit Score: 38.93  E-value: 2.38e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1167234569  60 IGPGLAMPHARPENGVIKTGyALVTLKKGVEFGDGENDPVDVLVFMAAKDSASHTE-EAMSQIAG 123
Cdd:TIGR01419  57 VGNGIAIPHGRLSGLKQPVG-VFIRLDAPVDFDALDGKPVDLLFALLVPENATAEHlEALSRIAR 120
PRK13779 PRK13779
bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional
 4-148 3.01e-04

bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional


Pssm-ID: 237502 [Multi-domain]  Cd Length: 503  Bit Score: 39.86  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1167234569   4 FEFLKSNgtIALDMEAADWKDAIRKGGSLLLQAGCCDGKYVEAMIDGCVRNGPYfvIGPGLAMPHARPE--NGVIKTGYA 81
Cdd:PRK13779    2 LNLSESN--IHLNAQAINKQQAIEMAAAALEQAGNVENGYLQGMLARELQTSTF--LGNGIAIPHGTLDtrHMVKNTGVQ 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1167234569  82 LVTLKKGVEFGDGenDPVDVLVFMAAKdSASHTeEAMSQIAGFCDNLDWLMELRVAKDVKSVVDLLS 148
Cdd:PRK13779   78 IFQFPQGIEWGEG--NIAYVVIGIAAR-SDEHL-SLLRQLTHVLSDEDTAAKLATLTDVKEFRAILM 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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